☰

John P. Perkins - Publications

Affiliations: 
1968-1977 Pharmacology University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
 1977-1980 Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
 1980-1989 Pharmacology Yale University, New Haven, CT 
 1989- Pharmacology The University of Texas Southwestern Medical Center, USA 
Website:
https://www.aspet.org/aspet/donate/travel-award-funds/memorial-travel-award-fund#:~:text=John%20P.%20Perkins%20(1937%E2%80%932002
Tree Info Similar researchers PubMed Report error

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Perkins J, Bertino JR. STIMULATION OF DIHYDROFOLATE REDUCTASE ACTIVITY BY p-CHLOROMERCURIBENZOATE. Biochemical and Biophysical Research Communications. 15: 121-6. PMID 26410903 DOI: 10.1016/0006-291X(64)90310-9  0.49
1996 Perkins JP. Pharmacology education in the USA: II. The role of graduate programmes. Trends in Pharmacological Sciences. 17: 42-5. PMID 8929837  0.183
1995 Parker EM, Swigart P, Nunnally MH, Perkins JP, Ross EM. Carboxyl-terminal domains in the avian beta 1-adrenergic receptor that regulate agonist-promoted endocytosis. The Journal of Biological Chemistry. 270: 6482-7. PMID 7896782 DOI: 10.1074/Jbc.270.12.6482  0.348
1993 Liao JF, Perkins JP. Differential effects of antimycin A on endocytosis and exocytosis of transferrin also are observed for internalization and externalization of beta-adrenergic receptors. Molecular Pharmacology. 44: 364-70. PMID 8394993  0.385
1993 Fields KK, Perkins JP, Hiemenz JW, Zorsky PE, Janssen WE, Kronish LE, Machak MC, Elfenbein GJ. Intensive dose ifosfamide, carboplatin, and etoposide followed by autologous stem cell rescue: results of a phase I/II study in breast cancer patients. Surgical Oncology. 2: 87-95. PMID 7902764  0.187
1992 Kurz JB, Perkins JP. Isoproterenol-initiated beta-adrenergic receptor diacytosis in cultured cells. Molecular Pharmacology. 41: 375-81. PMID 1347147  0.362
1990 Hertel C, Nunnally MH, Wong SK, Murphy EA, Ross EM, Perkins JP. A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors. The Journal of Biological Chemistry. 265: 17988-94. PMID 1976632  0.386
1987 Toews ML, Liang M, Perkins JP. Agonists and phorbol esters desensitize beta-adrenergic receptors by different mechanisms Molecular Pharmacology. 32: 737-742. PMID 2892124  0.406
1986 Hertel C, Coulter SJ, Perkins JP. The involvement of cellular ATP receptor-mediated internalization of epidermal growth factor and hormone-induced internalization of β-adrenergic receptors Journal of Biological Chemistry. 261: 5974-5980. PMID 3009438  0.37
1985 Wakshull E, Hertel C, O'Keefe EJ, Perkins JP. Cellular redistribution of β-adrenergic receptors in a human astrocytoma cell line: A comparison with the epidermal growth factor receptor in murine fibroblasts Journal of Cellular Biochemistry. 29: 127-141. PMID 2999168  0.338
1985 Hertel C, Coulter SJ, Perkins JP. A comparison of catecholamine-induced internalization of β-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide Journal of Biological Chemistry. 260: 12547-12553. PMID 2995380  0.365
1985 Doss RC, Kramarcy NR, Harden TK, Perkins JP. Effects of tunicamycin on the expression of beta-adrenergic receptors in human astrocytoma cells during growth and recovery from agonist-induced down-regulation. Molecular Pharmacology. 27: 507-16. PMID 2985949  0.339
1985 Kierszenbaum AL, Spruill WA, White MG, Tres LL, Perkins JP. Rat Sertoli cells acquire a beta-adrenergic response during primary culture. Proceedings of the National Academy of Sciences of the United States of America. 82: 2049-53. PMID 2984678  0.362
1984 Perkins JP. Mechanisms of receptor regulation. European Journal of Respiratory Diseases. Supplement. 135: 174-86. PMID 6329804  0.331
1984 Perkins JP, Toews ML, Harden TK. Regulation of beta-adrenergic receptors during exposure of astrocytoma cells to catecholamines Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 37-46. PMID 6145327  0.322
1984 Toews ML, Perkins JP. Agonist-induced changes in β-adrenergic receptors on intact cells Journal of Biological Chemistry. 259: 2227-2235. PMID 6142040  0.372
1984 Hertel C, Perkins JP. Receptor-specific mechanisms of desensitization of β-adrenergic receptor function Molecular and Cellular Endocrinology. 37: 245-256. PMID 6094283 DOI: 10.1016/0303-7207(84)90094-7  0.379
1984 Waldo GL, Doss RC, Perkins JP, Harden TK. Use of a density shift method to assess beta-adrenergic receptor synthesis during recovery from catecholamine-induced down-regulation in human astrocytoma cells. Molecular Pharmacology. 26: 424-9. PMID 6092895  0.366
1984 Toews ML, Waldo GL, Harden TK, Perkins JP. Relationship between an altered membrane form and a low affinity form of the β-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization Journal of Biological Chemistry. 259: 11844-11850. PMID 6090447  0.372
1983 Hertel C, Staehelin M, Perkins JP. Evidence for intravesicular β-adrenergic receptors in membrane fractions from desensitized cells: Binding of the hydrophilic ligand CGP-12177 only in the presence of alamethicin Journal of Cyclic Nucleotide and Protein Phosphorylation Research. 9: 119-128. PMID 6315796  0.33
1983 Frederich RC, Waldo GL, Harden TK, Perkins JP. Characterization of agonist-induced beta-adrenergic receptor-specific desensitization in C62B glioma cells. Journal of Cyclic Nucleotide and Protein Phosphorylation Research. 9: 103-18. PMID 6315795  0.367
1983 Waldo GL, Northup JK, Perkins JP, Harden TK. Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization. The Journal of Biological Chemistry. 258: 13900-8. PMID 6315711  0.386
1983 Toews ML, Harden TK, Perkins JP. High-affinity binding of agonists to β-adrenergic receptors on intact cells Proceedings of the National Academy of Sciences of the United States of America. 80: 3553-3557. PMID 6134286  0.331
1981 Doss RC, Perkins JP, Harden TK. Recovery of beta-adrenergic receptors following long term exposure of astrocytoma cells to catecholamine. Role of protein synthesis. The Journal of Biological Chemistry. 256: 12281-6. PMID 6271779  0.391
1981 Kurz JB, Perkins JP. Cystic fibrosis fibroblasts respond normally to isoproterenol. Pediatric Research. 15: 1328-33. PMID 6170925 DOI: 10.1203/00006450-198110000-00004  0.228
1980 Harden TK, Cotton CU, Waldo GL, Lutton JK, Perkins JP. Catecholamine-induced alteration in sedimentation behavior of membrane bound beta-adrenergic receptors. Science (New York, N.Y.). 210: 441-3. PMID 6254143 DOI: 10.1126/science.6254143  0.387
1980 Su YF, Harden TK, Perkins JP. Catecholamine-specific desensitization of adenylate cyclase. Evidence for a multistep process. The Journal of Biological Chemistry. 255: 7410-9. PMID 6248556  0.24
1979 Kurz JB, Perkins JP, Buchwald M. Killing of fibroblasts by dexamethasone or dibutyryl adenosine 3',5'-monophosphate is not a valid test for cystic fibrosis. Science (New York, N.Y.). 206: 1317-9. PMID 229552 DOI: 10.1126/Science.229552  0.296
1979 Harden TK, Su YF, Perkins JP. Catecholamine-induced desensitization involves an uncoupling of beta-adrenergic receptors and adenylate cyclase. Journal of Cyclic Nucleotide Research. 5: 99-106. PMID 221555  0.387
1979 Harden TK, Foster SJ, Perkins JP. Differential expression of components of the adenylate cyclase system during growth of astrocytoma cells in culture. The Journal of Biological Chemistry. 254: 4416-22. PMID 220244  0.231
1979 Su YF, Harden TK, Perkins JP. Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors. The Journal of Biological Chemistry. 254: 38-41. PMID 214444  0.366
1979 Perkins JP, Su YF, Harden TK. Adaptive changes in the responsiveness of adenylate cyclase to catecholamines. Drug and Alcohol Dependence. 4: 279-94. PMID 43242 DOI: 10.1016/0376-8716(79)90011-5  0.38
1978 Johnson GL, Wolfe BB, Harden TK, Molinoff PB, Perkins JP. Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells. The Journal of Biological Chemistry. 253: 1472-80. PMID 203594  0.367
1978 Johnson GL, Harden TK, Perkins JP. Regulation of adenosine 3':5'-monophosphate content of rous sarcoma virus-transformed human astrocytoma cells. Effects of cholera toxin on the responsiveness to catecholamines and prostaglandins. The Journal of Biological Chemistry. 253: 1465-71. PMID 203593  0.374
1978 Leichtling BH, Drotar A, Howell S, Su JL, Perkins JP, Wicks WD. Expression of the regulation of cAMP metabolism in somatic cell hybrids. Experimental Cell Research. 113: 391-402. PMID 95676  0.343
1978 Perkins JP, Johnson GL, Harden TK. Drug-induced modification of the responsiveness of adenylate cyclase to hormones. Advances in Cyclic Nucleotide Research. 9: 19-32. PMID 27078  0.218
1977 Foster SJ, Perkins JP. Glucocorticoids increase the responsiveness of cells in culture to prostaglandin E1. Proceedings of the National Academy of Sciences of the United States of America. 74: 4816-20. PMID 200933  0.32
1977 Ortmann R, Perkins JP. Stimulation of adenosine 3':5'-monophosphate formation by prostaglandins in human astrocytoma cells. Inhibition by nonsteroidal anti-inflammatory agents. The Journal of Biological Chemistry. 252: 6018-25. PMID 197079  0.314
1977 Harden TK, Wolfe BB, Sporn JR, Perkins JP, Molinoff PB. Ontogeny of beta-adrenergic receptors in rat cerebral cortex. Brain Research. 125: 99-108. PMID 192417 DOI: 10.1016/0006-8993(77)90362-6  0.34
1976 Su YF, Johnson GL, Cubeddu L, Leichtling BH, Ortmann R, Perkins JP. Regulation of adenosine 3':5'-monophosphate content of human astrocytoma cells: mechanism of agonist-specific desensitization. Journal of Cyclic Nucleotide Research. 2: 271-85. PMID 184126  0.316
1976 Su YF, Cubeddu L, Perkins JP. Regulation of adenosine 3':5'-monophosphate content of human astrocytoma cells: desensitization to catecholamines and prostaglandins. Journal of Cyclic Nucleotide Research. 2: 257-70. PMID 184125  0.407
1976 Leichtling BH, Drotar AM, Ortmann R, Perkins JP. Growth of astrocytoma cells in the presence of prostaglandin E1: effect on the regulation of cyclic AMP metabolism. Journal of Cyclic Nucleotide Research. 2: 89-97. PMID 177468  0.316
1975 Perkins JP, Moore MM, Kalisker A, Su YF. Regulation of cyclic AMP content in normal and malignant brain cells Advances in Cyclic Nucleotide Research. 5: 641-658. PMID 165690  0.353
1975 Clark RB, Su YF, Ortmann R, Cubeddu L, Johnson GL, Perkins JP. Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells. Metabolism: Clinical and Experimental. 24: 343-58. PMID 165356 DOI: 10.1016/0026-0495(75)90115-8  0.588
1974 Clark RB, Gross R, Su YF, Perkins JP. Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides. The Journal of Biological Chemistry. 249: 5296-303. PMID 4369127  0.317
1973 Hayakawa T, Perkins JP, Krebs EG. Studies of the subunit structure of rabbit skeletal muscle phosphorylase kinase. Biochemistry. 12: 574-80. PMID 4734894 DOI: 10.1021/Bi00728A002  0.612
1973 Hayakawa T, Perkins JP, Walsh DA, Krebs EG. Physiochemical properties of rabbit skeletal muscle phosphorylase kinase. Biochemistry. 12: 567-73. PMID 4734893 DOI: 10.1021/Bi00728A001  0.682
1973 Kalisker A, Rutledge CO, Perkins JP. Effect of nerve degeneration by 6-hydroxydopamine on catecholamine-stimulated adenosine 3',5'-monophosphate formation in rat cerebral cortex. Molecular Pharmacology. 9: 619-29. PMID 4363016  0.229
1973 Perkins JP. Adenyl cyclase. Advances in Cyclic Nucleotide Research. 3: 1-64. PMID 4357643  0.309
1973 Perkins JP, Moore MM. Characterization of the adrenergic receptors mediating a rise in cyclic 3',5' adenosine monophosphate in rat cerebral cortex Journal of Pharmacology and Experimental Therapeutics. 185: 371-378. PMID 4350039  0.326
1973 Perkins JP, Moore MM. Regulation of the adenosine cyclic 3',5' monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine Molecular Pharmacology. 9: 774-782. PMID 4148655  0.292
1972 Macintyre EH, Wintersgill CJ, Perkins JP, Vatter AE. The responses in culture of human tumour astrocytes and neuroblasts to N 6 , O 2' -dibutyryl adenosine 3',5'-monophosphoric acid. Journal of Cell Science. 11: 639-67. PMID 4346215  0.213
1971 Perkins JP, Moore MM. Adenyl cyclase of rat cerebral cortex. Activation of sodium fluoride and detergents Journal of Biological Chemistry. 246: 62-68. PMID 5541774  0.219
1971 Clark RB, Perkins JP. Regulation of adenosine 3':5'-cyclic monophosphate concentration in cultured human astrocytoma cells by catecholamines and histamine. Proceedings of the National Academy of Sciences of the United States of America. 68: 2757-60. PMID 4330940  0.357
1970 Walsh DA, Krebs EG, Reimann EM, Brostrom MA, Corbin JD, Hickenbottom JP, Soderling TR, Perkins JP. The receptor protein for cyclic AMP in the control of glycogenolysis. Advances in Biochemical Psychopharmacology. 3: 265-85. PMID 4331459  0.696
1970 Fox BW, Perkins JP, Prusoff WH. Inhibitory action of thymine ribonucleoside and other pyrimidine derivatives on the cleavage of 5-iodo-deoxy-uridine by mouse-liver extract Chemico-Biological Interactions. 1: 331-340. PMID 4258869 DOI: 10.1016/0009-2797(70)90002-5  0.267
1969 Perkins JP, Hillman G, Fischer D, Bertino JR. Antibody to dihydrofolate reductase from a methotrexate-resistant subline of the L1210 lymphoma. Molecular Pharmacology. 5: 213-8. PMID 4389029  0.528
1968 Walsh DA, Perkins JP, Krebs EG. An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle. The Journal of Biological Chemistry. 243: 3763-5. PMID 4298072  0.695
1967 Perkins JP, Hillcoat BL, Bertino JR. Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification and properties. The Journal of Biological Chemistry. 242: 4771-6. PMID 4964810  0.536
1967 Hillcoat BL, Perkins JP, Bertino JR. Dihydrofolate reductase from the L1210 R murine lymphoma. Further studies on the binding of substrates and inhibitors to the enzyme. The Journal of Biological Chemistry. 242: 4777-81. PMID 4383525  0.55
1966 Bertino JR, Iannotti AT, Perkins JP, Johns DG. Dihydrofolate reductase from guinea pig liver and small intestine. Biochemical Pharmacology. 15: 563-71. PMID 5227348 DOI: 10.1016/0006-2952(66)90023-2  0.524
1966 Perkins JP, Bertino JR. Dihydrofolate reductase from the L1210R murine lymphoma. Fluorometric measurements of the interaction of the enzyme with coenzymes, substrates, and inhibitors. Biochemistry. 5: 1005-12. PMID 4380350 DOI: 10.1021/bi00867a028  0.543
1965 PERKINS JP, BERTINO JR. INTERACTION OF ORGANIC MERCURIAL COMPOUNDS WITH DIHYDROFOLATE REDUCTASE FROM EHRLICH ASCITES CARCINOMA CELLS. Biochemistry. 4: 847-53. PMID 14337700 DOI: 10.1021/bi00881a008  0.534
1965 BERTINO JR, PERKINS JP, JOHNS DG. PURIFICATION AND PROPERTIES OF DIHYDROFOLATE REDUCTASE FROM EHRLICH ASCITES CARCINOMA CELLS. Biochemistry. 4: 839-46. PMID 14337699 DOI: 10.1021/bi00881a007  0.548
Show low-probability matches.