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Susanne Koch, Ph.D. - Publications

Affiliations: 
Columbia University Columbia University, New York, NY 
Area:
Retinal degeneration, Gene therapy, iPS cells
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jentzsch MC, Tsang SH, Koch SF. A New Preclinical Model of Retinitis Pigmentosa Due to Deficiency. Ophthalmology Science. 3: 100332. PMID 37363133 DOI: 10.1016/j.xops.2023.100332  0.458
2023 Díaz-Lezama N, Kajtna J, Wu J, Ayten M, Koch SF. Microglial and macroglial dynamics in a model of retinitis pigmentosa. Vision Research. 210: 108268. PMID 37295269 DOI: 10.1016/j.visres.2023.108268  0.303
2022 Kajtna J, Tsang SH, Koch SF. Late-stage rescue of visually guided behavior in the context of a significantly remodeled retinitis pigmentosa mouse model. Cellular and Molecular Life Sciences : Cmls. 79: 148. PMID 35195763 DOI: 10.1007/s00018-022-04161-0  0.467
2019 Wert KJ, Koch SF, Velez G, Hsu CW, Mahajan M, Bassuk AG, Tsang SH, Mahajan VB. CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials. Human Mutation. PMID 31403230 DOI: 10.1002/Humu.23894  0.615
2019 Sancho-Pelluz J, Cui X, Lee W, Tsai YT, Wu WH, Justus S, Washington I, Hsu CW, Park KS, Koch S, Velez G, Bassuk AG, Mahajan VB, Lin CS, Tsang SH. Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a Rho mutation. Cellular and Molecular Life Sciences : Cmls. PMID 30976840 DOI: 10.1007/S00018-019-03090-9  0.481
2018 Koch SF, Tsang SH. Success of Gene Therapy in Late-Stage Treatment. Advances in Experimental Medicine and Biology. 1074: 101-107. PMID 29721933 DOI: 10.1007/978-3-319-75402-4_13  0.445
2017 Koch SF, Duong JK, Hsu CW, Tsai YT, Lin CS, Wahl-Schott CA, Tsang SH. Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. PMID 28468800 DOI: 10.1073/Pnas.1615394114  0.45
2017 Michalakis S, Shaltiel L, Sothilingam V, Koch S, Schludi V, Krause S, Zeitz C, Audo I, Lancelot ME, Hamel C, Meunier I, Preising MN, Friedburg C, Lorenz B, Zabouri N, et al. Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2. Human Molecular Genetics. 26: 466. PMID 28365780 DOI: 10.1093/Hmg/Ddw424  0.329
2016 Schön C, Asteriti S, Koch S, Sothilingam V, Garcia Garrido M, Tanimoto N, Herms J, Seeliger MW, Cangiano L, Biel M, Michalakis S. Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia. Human Molecular Genetics. PMID 26740549 DOI: 10.1093/Hmg/Ddv639  0.433
2015 Koch SF, Tsai YT, Duong JK, Wu WH, Hsu CW, Wu WP, Bonet-Ponce L, Lin CS, Tsang SH. Halting progressive neurodegeneration in advanced retinitis pigmentosa. The Journal of Clinical Investigation. 125: 3704-13. PMID 26301813 DOI: 10.1172/Jci82462  0.47
2014 Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, et al. Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. Plos One. 9: e112142. PMID 25392995 DOI: 10.1371/Journal.Pone.0112142  0.364
2014 Michalakis S, Koch S, Sothilingam V, Garrido MG, Tanimoto N, Schulze E, Becirovic E, Koch F, Seide C, Beck SC, Seeliger MW, Mühlfriedel R, Biel M. Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. Advances in Experimental Medicine and Biology. 801: 733-9. PMID 24664765 DOI: 10.1007/978-1-4614-3209-8_92  0.334
2014 Michalakis S, Shaltiel L, Sothilingam V, Koch S, Schludi V, Krause S, Zeitz C, Audo I, Lancelot ME, Hamel C, Meunier I, Preising MN, Friedburg C, Lorenz B, Zabouri N, et al. Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2. Human Molecular Genetics. 23: 1538-50. PMID 24163243 DOI: 10.1093/Hmg/Ddt541  0.398
2013 Michalakis S, Schäferhoff K, Spiwoks-Becker I, Zabouri N, Koch S, Koch F, Bonin M, Biel M, Haverkamp S. Characterization of neurite outgrowth and ectopic synaptogenesis in response to photoreceptor dysfunction. Cellular and Molecular Life Sciences : Cmls. 70: 1831-47. PMID 23269435 DOI: 10.1007/S00018-012-1230-Z  0.348
2012 Koch S, Sothilingam V, Garcia Garrido M, Tanimoto N, Becirovic E, Koch F, Seide C, Beck SC, Seeliger MW, Biel M, Mühlfriedel R, Michalakis S. Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. Human Molecular Genetics. 21: 4486-96. PMID 22802073 DOI: 10.1093/Hmg/Dds290  0.43
2012 Michalakis S, Mühlfriedel R, Tanimoto N, Krishnamoorthy V, Koch S, Fischer MD, Becirovic E, Bai L, Huber G, Beck SC, Fahl E, Büning H, Schmidt J, Zong X, Gollisch T, et al. Gene therapy restores missing cone-mediated vision in the CNGA3-/- mouse model of achromatopsia. Advances in Experimental Medicine and Biology. 723: 183-9. PMID 22183332 DOI: 10.1007/978-1-4614-0631-0_25  0.432
2012 Shaltiel L, Michalakis S, Sothilingam V, Garrido MG, Koch S, Tanimoto N, Seeliger MW, Biel M, Wahl-Schott CA. Visual Function in CaV1.4-Deficient Mice Biophysical Journal. 102: 1-7. DOI: 10.1016/J.Bpj.2011.11.706  0.402
2010 Michalakis S, Mühlfriedel R, Tanimoto N, Krishnamoorthy V, Koch S, Fischer MD, Becirovic E, Bai L, Huber G, Beck SC, Fahl E, Büning H, Paquet-Durand F, Zong X, Gollisch T, et al. Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2057-63. PMID 20628362 DOI: 10.1038/Mt.2010.149  0.425
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