| Year |
Citation |
Score |
| 2023 |
Schlueter DJ, Sulieman L, Mo H, Keaton JM, Ferrara TM, Williams A, Qian J, Stubblefield O, Zeng C, Tran TC, Bastarache L, Dai J, Babbar A, Ramirez A, Goleva SB, et al. Systematic replication of smoking disease associations using survey responses and EHR data in the All of Us Research Program. Journal of the American Medical Informatics Association : Jamia. PMID 37885303 DOI: 10.1093/jamia/ocad205 |
0.424 |
|
| 2023 |
Schuler BA, Bastarache L, Wang J, He J, Van Driest SL, Denny JC. Population genetic testing and SERPINA1 sequencing identifies unidentified alpha-1 antitrypsin deficiency alleles and gene-environment interaction with hepatitis C infection. Plos One. 18: e0286469. PMID 37651384 DOI: 10.1371/journal.pone.0286469 |
0.427 |
|
| 2023 |
Cassini T, Bastarache L, Zeng C, Han ST, Wang J, He J, Denny JC. A Test of Automated Use of Electronic Health Records to Aid in Diagnosis of Genetic Disease. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 100966. PMID 37622442 DOI: 10.1016/j.gim.2023.100966 |
0.476 |
|
| 2023 |
Bastarache L, Delozier S, Pandit A, He J, Lewis A, Annis AC, LeFaive J, Denny JC, Carroll RJ, Altman RB, Hughey JJ, Zawistowski M, Peterson JF. The phenotype-genotype reference map: Improving biobank data science through replication. American Journal of Human Genetics. PMID 37607538 DOI: 10.1016/j.ajhg.2023.07.012 |
0.527 |
|
| 2023 |
Allaire P, He J, Mayer J, Moat L, Gerstenberger P, Wilhorn R, Strutz S, Kim DSL, Zeng C, Cox N, Shay JW, Denny J, Bastarache L, Hebbring S. Genetic and clinical determinants of telomere length. Hgg Advances. 4: 100201. PMID 37216007 DOI: 10.1016/j.xhgg.2023.100201 |
0.542 |
|
| 2022 |
Robinson JR, Carroll RJ, Bastarache L, Chen Q, Pirruccello J, Mou Z, Wei WQ, Connolly J, Mentch F, Crane PK, Hebbring SJ, Crosslin DR, Gordon AS, Rosenthal EA, Stanaway IB, et al. Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics. Obesity (Silver Spring, Md.). PMID 36372681 DOI: 10.1002/oby.23561 |
0.469 |
|
| 2022 |
Aref L, Bastarache L, Hughey JJ. The phers R package: using phenotype risk scores based on electronic health records to study Mendelian disease and rare genetic variants. Bioinformatics (Oxford, England). PMID 36083022 DOI: 10.1093/bioinformatics/btac619 |
0.317 |
|
| 2022 |
Zeng C, Bastarache LA, Tao R, Venner E, Hebbring S, Andujar JD, Bland ST, Crosslin DR, Pratap S, Cooley A, Pacheco JA, Christensen KD, Perez E, Zawatsky CLB, Witkowski L, et al. Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases. Jama Oncology. PMID 35446370 DOI: 10.1001/jamaoncol.2022.0373 |
0.477 |
|
| 2022 |
Irlmeier R, Hughey JJ, Bastarache L, Denny JC, Chen Q. Cox Regression is Robust to Inaccurate EHR-extracted Event Time-an Application to EHR-based GWAS. Bioinformatics (Oxford, England). PMID 35157022 DOI: 10.1093/bioinformatics/btac086 |
0.457 |
|
| 2022 |
Bastarache L, Denny JC, Roden DM. Phenome-Wide Association Studies. Jama. 327: 75-76. PMID 34982132 DOI: 10.1001/jama.2021.20356 |
0.498 |
|
| 2021 |
Bastarache L. Using Phecodes for Research with the Electronic Health Record: From PheWAS to PheRS. Annual Review of Biomedical Data Science. 4: 1-19. PMID 34465180 DOI: 10.1146/annurev-biodatasci-122320-112352 |
0.312 |
|
| 2020 |
Goldstein JA, Weinstock JS, Bastarache LA, Larach DB, Fritsche LG, Schmidt EM, Brummett CM, Kheterpal S, Abecasis GR, Denny JC, Zawistowski M. LabWAS: Novel findings and study design recommendations from a meta-analysis of clinical labs in two independent biobanks. Plos Genetics. 16: e1009077. PMID 33175840 DOI: 10.1371/journal.pgen.1009077 |
0.541 |
|
| 2020 |
Pividori M, Rajagopal PS, Barbeira A, Liang Y, Melia O, Bastarache L, Park Y, Consortium G, Wen X, Im HK. PhenomeXcan: Mapping the genome to the phenome through the transcriptome. Science Advances. 6. PMID 32917697 DOI: 10.1126/Sciadv.Aba2083 |
0.395 |
|
| 2020 |
Zhong X, Yin Z, Jia G, Zhou D, Wei Q, Faucon A, Evans P, Gamazon ER, Li B, Tao R, Rzhetsky A, Bastarache L, Cox NJ. Electronic health record phenotypes associated with genetically regulated expression of CFTR and application to cystic fibrosis. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32296164 DOI: 10.1038/S41436-020-0786-5 |
0.367 |
|
| 2020 |
Bajaj A, Ihegword A, Qiu C, Small AM, Wei WQ, Bastarache L, Feng Q, Kember RL, Risman M, Bloom RD, Birtwell DL, Williams H, Shaffer CM, Chen J, Center RG, et al. Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways. Kidney International. PMID 32247630 DOI: 10.1016/J.Kint.2020.01.027 |
0.557 |
|
| 2020 |
Sulieman L, He J, Carroll R, Bastarache L, Ramirez A. SAT-LB111 Improving Classification of Diabetes Etiology in Electronic Resources Using Phenotype Algorithms and Polygenic Risk Scores Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2239 |
0.362 |
|
| 2019 |
Hughey JJ, Rhoades SD, Fu DY, Bastarache L, Denny JC, Chen Q. Cox regression increases power to detect genotype-phenotype associations in genomic studies using the electronic health record. Bmc Genomics. 20: 805. PMID 31684865 DOI: 10.1186/S12864-019-6192-1 |
0.578 |
|
| 2019 |
Bastarache L, Hughey JJ, Goldstein JA, Bastraache JA, Das S, Zaki NC, Zeng C, Tang LA, Roden DM, Denny JC. Improving the phenotype risk score as a scalable approach to identifying patients with Mendelian disease. Journal of the American Medical Informatics Association : Jamia. PMID 31609419 DOI: 10.1093/Jamia/Ocz179 |
0.538 |
|
| 2019 |
Robinson JR, Carroll RJ, Bastarache L, Chen Q, Mou Z, Wei WQ, Connolly JJ, Mentch F, Sleiman P, Crane PK, Hebbring SJ, Stanaway IB, Crosslin DR, Gordon AS, Rosenthal EA, et al. Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization. World Journal of Surgery. PMID 31605180 DOI: 10.1007/S00268-019-05202-9 |
0.497 |
|
| 2019 |
Wu P, Gifford A, Meng X, Li X, Campbell H, Varley T, Zhao J, Carroll R, Bastarache L, Denny JC, Theodoratou E, Wei WQ. Developing and Evaluating Mappings of ICD-10 and ICD-10-CM Codes to PheCodes. Jmir Medical Informatics. PMID 31553307 DOI: 10.2196/14325 |
0.517 |
|
| 2019 |
Donovan BM, Bastarache L, Turi KN, Zutter MM, Hartert TV. The Current State of Omics Technologies in the Clinical Management of Asthma and Allergic Diseases. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. PMID 31494234 DOI: 10.1016/J.Anai.2019.08.460 |
0.307 |
|
| 2019 |
Newman JH, Shaver A, Sheehan JH, Mallal S, Stone JH, Pillai S, Bastarache L, Riebau D, Allard-Chamard H, Stone WM, Perugino C, Pilkinton M, Smith SA, McDonnell WJ, Capra JA, et al. IgG4-related disease: Association with a rare gene variant expressed in cytotoxic T cells. Molecular Genetics & Genomic Medicine. e686. PMID 30993913 DOI: 10.1002/Mgg3.686 |
0.305 |
|
| 2019 |
Bastarache L, Bastarache JA, Denny JC. Case 40-2018: A Woman with Recurrent Sinusitis, Cough, and Bronchiectasis. The New England Journal of Medicine. 380: 1382-1383. PMID 30943357 DOI: 10.1056/Nejmc1901268 |
0.426 |
|
| 2019 |
Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. American Journal of Human Genetics. PMID 30827500 DOI: 10.1016/J.Ajhg.2019.01.017 |
0.533 |
|
| 2019 |
Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL, Fine RS, Guo X, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, ... ... Bastarache L, et al. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics. PMID 30778226 DOI: 10.1038/S41588-018-0334-2 |
0.339 |
|
| 2019 |
Safarova MS, Satterfield BA, Fan X, Austin EE, Ye Z, Bastarache L, Zheng N, Ritchie MD, Borthwick KM, Williams MS, Larson EB, Scrol A, Jarvik GP, Crosslin DR, Leppig K, et al. A phenome-wide association study to discover pleiotropic effects of , , and . Npj Genomic Medicine. 4: 3. PMID 30774981 DOI: 10.1038/S41525-019-0078-7 |
0.605 |
|
| 2019 |
Salem JE, Shoemaker MB, Bastarache L, Shaffer CM, Glazer AM, Kroncke B, Wells QS, Shi M, Straub P, Jarvik GP, Larson EB, Velez Edwards DR, Edwards TL, Davis LK, Hakonarson H, et al. Association of Thyroid Function Genetic Predictors With Atrial Fibrillation: A Phenome-Wide Association Study and Inverse-Variance Weighted Average Meta-analysis. Jama Cardiology. PMID 30673079 DOI: 10.1001/Jamacardio.2018.4615 |
0.488 |
|
| 2019 |
Morley T, Bastarache L, Cox N, Ruderfer D. 11 Leveraging Phenotype Data To Identify Potential Carriers Of Deleterious Genetic Variants European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.152 |
0.373 |
|
| 2018 |
Salem JE, Manouchehri A, Moey M, Lebrun-Vignes B, Bastarache L, Pariente A, Gobert A, Spano JP, Balko JM, Bonaca MP, Roden DM, Johnson DB, Moslehi JJ. Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study. The Lancet. Oncology. PMID 30442497 DOI: 10.1016/S1470-2045(18)30608-9 |
0.304 |
|
| 2018 |
Rhoades SD, Bastarache L, Denny JC, Hughey JJ. Pulling the covers in electronic health records for an association study with self-reported sleep behaviors. Chronobiology International. 1-11. PMID 30183400 DOI: 10.1080/07420528.2018.1508152 |
0.476 |
|
| 2018 |
Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, et al. A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nature Communications. 9: 3522. PMID 30166544 DOI: 10.1038/S41467-018-05624-4 |
0.415 |
|
| 2018 |
Feng Q, Wei WQ, Chung CP, Levinson RT, Sundermann AC, Mosley JD, Bastarache L, Ferguson JF, Cox NJ, Roden DM, Denny JC, Linton MF, Edwards DRV, Stein CM. Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. Plos Medicine. 15: e1002642. PMID 30153257 DOI: 10.1371/Journal.Pmed.1002642 |
0.488 |
|
| 2018 |
Zhou W, Nielsen JB, Fritsche LG, Dey R, Gabrielsen ME, Wolford BN, LeFaive J, VandeHaar P, Gagliano SA, Gifford A, Bastarache LA, Wei WQ, Denny JC, Lin M, Hveem K, et al. Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Nature Genetics. PMID 30104761 DOI: 10.1038/S41588-018-0184-Y |
0.466 |
|
| 2018 |
Jerome RN, Pulley JM, Roden DM, Shirey-Rice JK, Bastarache LA, Bernard G, Ekstrom L, Lancaster WJ, Denny JC. Reply to Ward and Colleagues' Comment on "Using Human Experiments of Nature to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors". Drug Safety. PMID 30066313 DOI: 10.1007/S40264-018-0701-Z |
0.368 |
|
| 2018 |
Bloodworth MH, Rusznak M, Bastarache L, Wang J, Denny JC, Peebles RS. Association of ST2 polymorphisms with atopy, asthma and leukemia. The Journal of Allergy and Clinical Immunology. PMID 29787780 DOI: 10.1016/J.Jaci.2018.03.020 |
0.498 |
|
| 2018 |
Goldstein JA, Bastarache LA, Denny JC, Pulley JM, Aronoff DM. PregOMICS-Leveraging systems biology and bioinformatics for drug repurposing in maternal-child health. American Journal of Reproductive Immunology (New York, N.Y. : 1989). e12971. PMID 29726581 DOI: 10.1111/Aji.12971 |
0.43 |
|
| 2018 |
Emdin CA, Khera AV, Chaffin M, Klarin D, Natarajan P, Aragam K, Haas M, Bick A, Zekavat SM, Nomura A, Ardissino D, Wilson JG, Schunkert H, McPherson R, Watkins H, ... ... Bastarache L, et al. Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease. Nature Communications. 9: 1613. PMID 29691411 DOI: 10.1038/S41467-018-03911-8 |
0.575 |
|
| 2018 |
Dahir KM, Tilden DR, Warner JL, Bastarache L, Smith DK, Gifford A, Ramirez AH, Simmons J, Black MM, Newman JH, Denny JC. Rare variants in the gene ALPL that cause hypophosphatasia are strongly associated with ovarian and uterine disorders. The Journal of Clinical Endocrinology and Metabolism. PMID 29659871 DOI: 10.1210/Jc.2017-02676 |
0.347 |
|
| 2018 |
Bastarache L, Hughey JJ, Hebbring S, Marlo J, Zhao W, Ho WT, Van Driest SL, McGregor TL, Mosley JD, Wells QS, Temple M, Ramirez AH, Carroll R, Osterman T, Edwards T, et al. Phenotype risk scores identify patients with unrecognized Mendelian disease patterns. Science (New York, N.Y.). 359: 1233-1239. PMID 29590070 DOI: 10.1126/Science.Aal4043 |
0.599 |
|
| 2018 |
Goldstein JA, Bastarache LA, Denny JC, Roden DM, Pulley JM, Aronoff DM. Calcium Channel Blockers as Drug Repurposing Candidates for Gestational Diabetes: Mining large scale genomic and electronic health records data to repurpose medications. Pharmacological Research. PMID 29448118 DOI: 10.1016/J.Phrs.2018.02.013 |
0.465 |
|
| 2018 |
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Bastarache L, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. 50: 26-41. PMID 29273807 DOI: 10.1038/S41588-017-0011-X |
0.383 |
|
| 2018 |
Robinson JR, Carroll RJ, Bastarache L, Mou Z, Jackson GP, Roden DM, Denny JC. Association of Obesity with Postoperative Complications Using Phenome-Wide Association Studies and Mendelian Randomization Journal of the American College of Surgeons. 227. DOI: 10.1016/J.Jamcollsurg.2018.07.192 |
0.503 |
|
| 2017 |
Jerome RN, Pulley JM, Roden DM, Shirey-Rice JK, Bastarache LA, R Bernard G, B Ekstrom L, Lancaster WJ, Denny JC. Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors. Drug Safety. PMID 29185237 DOI: 10.1007/S40264-017-0616-0 |
0.386 |
|
| 2017 |
Dohn MR, Kooker CG, Bastarache L, Jessen T, Rinaldi C, Varney S, Mazalouskas MD, Pan H, Oliver KH, Velez Edwards DR, Sutcliffe JS, Denny JC, Carneiro AMD. The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29038237 DOI: 10.1523/Jneurosci.1482-17.2017 |
0.464 |
|
| 2017 |
Karnes JH, Shaffer CM, Cronin R, Bastarache L, Gaudieri S, James I, Pavlos R, Steiner H, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Influence of human leukocyte antigen (HLA) alleles and killer cell immunoglobulin-like receptors (KIR) types on heparin-induced thrombocytopenia (HIT). Pharmacotherapy. PMID 28688202 DOI: 10.1002/Phar.1983 |
0.498 |
|
| 2017 |
Wei WQ, Bastarache LA, Carroll RJ, Marlo JE, Osterman TJ, Gamazon ER, Cox NJ, Roden DM, Denny JC. Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record. Plos One. 12: e0175508. PMID 28686612 DOI: 10.1371/Journal.Pone.0175508 |
0.471 |
|
| 2017 |
Zheng NS, Bastarache LA, Bastarache JA, Lu Y, Ware LB, Shu XO, Denny JC, Long J. A common deletion in the haptoglobin gene associated with blood cholesterol levels among Chinese women. Journal of Human Genetics. PMID 28659611 DOI: 10.1038/Jhg.2017.66 |
0.449 |
|
| 2017 |
Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM, Mosley JD, Zhao S, Raychaudhuri S, Mallal S, Ye Z, Mayer JG, Brilliant MH, Hebbring SJ, Roden DM, et al. Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Science Translational Medicine. 9. PMID 28490672 DOI: 10.1126/Scitranslmed.Aai8708 |
0.588 |
|
| 2017 |
Robinson JR, Kennedy VE, Doss Y, Bastarache L, Denny J, Warner JL. Defining the complex phenotype of severe systemic loxoscelism using a large electronic health record cohort. Plos One. 12: e0174941. PMID 28422977 DOI: 10.1371/Journal.Pone.0174941 |
0.494 |
|
| 2017 |
Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, et al. Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes. Circulation. Cardiovascular Genetics. 10. PMID 28416512 DOI: 10.1161/Circgenetics.116.001482 |
0.39 |
|
| 2017 |
Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, et al. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Assay and Drug Development Technologies. PMID 28379727 DOI: 10.1089/Adt.2016.772 |
0.508 |
|
| 2017 |
Karnes JH, Shaffer CM, Bastarache L, Gaudieri S, Glazer AM, Steiner HE, Mosley JD, Mallal S, Denny JC, Phillips EJ, Roden DM. Comparison of HLA allelic imputation programs. Plos One. 12: e0172444. PMID 28207879 DOI: 10.1371/Journal.Pone.0172444 |
0.513 |
|
| 2017 |
Boortz KA, Syring KE, Pound LD, Mo H, Bastarache L, Oeser JK, McGuinness OP, Denny JC, O'Brien R. Effects of G6pc2 deletion on body weight and cholesterol in mice. Journal of Molecular Endocrinology. PMID 28122818 DOI: 10.1530/Jme-16-0202 |
0.489 |
|
| 2016 |
Mosley JD, Van Driest SL, Wells QS, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, et al. Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile using Historical Data. Circulation. Cardiovascular Genetics. PMID 27780847 DOI: 10.1161/Circgenetics.116.001530 |
0.537 |
|
| 2016 |
Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS. Transcription factor ETV1 is essential for rapid conduction in the heart. The Journal of Clinical Investigation. PMID 27775552 DOI: 10.1172/Jci87968 |
0.477 |
|
| 2016 |
Teixeira PL, Wei WQ, Cronin RM, Mo H, VanHouten JP, Carroll RJ, LaRose E, Bastarache LA, Rosenbloom ST, Edwards TL, Roden DM, Lasko TA, Dart RA, Nikolai AM, Peissig PL, et al. Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals. Journal of the American Medical Informatics Association : Jamia. PMID 27497800 DOI: 10.1093/Jamia/Ocw071 |
0.443 |
|
| 2016 |
Li H, Achour I, Bastarache L, Berghout J, Gardeux V, Li J, Lee Y, Pesce L, Yang X, Ramos KS, Foster I, Denny JC, Moore JH, Lussier YA. Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. Npj Genomic Medicine. 1. PMID 27482468 DOI: 10.1038/Npjgenmed.2016.6 |
0.578 |
|
| 2016 |
Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, ... ... Bastarache L, et al. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. American Journal of Human Genetics. PMID 27346689 DOI: 10.1016/J.Ajhg.2016.05.003 |
0.561 |
|
| 2016 |
Denny JC, Bastarache L, Roden DM. Phenome-Wide Association Studies as a Tool to Advance Precision Medicine. Annual Review of Genomics and Human Genetics. PMID 27147087 DOI: 10.1146/Annurev-Genom-090314-024956 |
0.594 |
|
| 2016 |
Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Identifying genetically driven clinical phenotypes using linear mixed models. Nature Communications. 7: 11433. PMID 27109359 DOI: 10.1038/Ncomms11433 |
0.591 |
|
| 2016 |
Simonti CN, Vernot B, Bastarache L, Bottinger E, Carrell DS, Chisholm RL, Crosslin DR, Hebbring SJ, Jarvik GP, Kullo IJ, Li R, Pathak J, Ritchie MD, Roden DM, Verma SS, et al. The phenotypic legacy of admixture between modern humans and Neandertals. Science (New York, N.Y.). 351: 737-41. PMID 26912863 DOI: 10.1126/Science.Aad2149 |
0.572 |
|
| 2016 |
Feng Q, Wei WQ, Chung CP, Levinson RT, Bastarache L, Denny JC, Stein CM. The effect of genetic variation in PCSK9 on the LDL-cholesterol response to statin therapy. The Pharmacogenomics Journal. PMID 26902539 DOI: 10.1038/Tpj.2016.3 |
0.52 |
|
| 2016 |
Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, et al. Joint mouse-human phenome-wide association to test gene function and disease risk. Nature Communications. 7: 10464. PMID 26833085 DOI: 10.1038/Ncomms10464 |
0.575 |
|
| 2016 |
Claar DD, Larkin EK, Bastarache L, Blackwell TS, Loyd JE, Hartert TV, Denny JC, Kropski JA. A Phenome-Wide Association Study Identifies a Novel Asthma Risk Locus Near TERC. American Journal of Respiratory and Critical Care Medicine. 193: 98-100. PMID 26720789 DOI: 10.1164/Rccm.201507-1267Le |
0.517 |
|
| 2016 |
Osterman TJ, Bastarache L, Wei W, Mosley JD, Denny JC. Using a gene-environment interaction study to evaluate risk for lung cancer. Journal of Clinical Oncology. 34: 1524-1524. DOI: 10.1200/Jco.2016.34.15_Suppl.1524 |
0.34 |
|
| 2015 |
Karol SE, Yang W, Van Driest SL, Chang TY, Kaste S, Bowton E, Basford M, Bastarache L, Roden DM, Denny JC, Larsen E, Winick N, Carroll WL, Cheng C, Pei D, et al. Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Blood. PMID 26265699 DOI: 10.1182/Blood-2015-05-643601 |
0.553 |
|
| 2015 |
Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei WQ, Teixeira PL, Bastarache L, Crawford DC, Li R, Manolio TA, Bottinger EP, McCarty CA, et al. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. The Pharmacogenomics Journal. PMID 26169577 DOI: 10.1038/Tpj.2015.51 |
0.571 |
|
| 2015 |
Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, et al. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. Plos One. 10: e0122271. PMID 25849893 DOI: 10.1371/Journal.Pone.0122271 |
0.556 |
|
| 2014 |
Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, ... ... Bastarache LA, et al. Inactivating mutations in NPC1L1 and protection from coronary heart disease. The New England Journal of Medicine. 371: 2072-82. PMID 25390462 DOI: 10.1056/Nejmoa1405386 |
0.417 |
|
| 2014 |
Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, et al. Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Frontiers in Genetics. 5: 250. PMID 25177340 DOI: 10.3389/Fgene.2014.00250 |
0.593 |
|
| 2014 |
Mosley JD, Van Driest SL, Weeke PE, Delaney JT, Wells QS, Bastarache L, Roden DM, Denny JC. Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations Plos One. 9. PMID 24949630 DOI: 10.1371/Journal.Pone.0100322 |
0.456 |
|
| 2014 |
Carroll RJ, Bastarache L, Denny JC. R PheWAS: Data analysis and plotting tools for phenome-wide association studies in the R environment Bioinformatics. 30: 2375-2376. PMID 24733291 DOI: 10.1093/Bioinformatics/Btu197 |
0.589 |
|
| 2014 |
Shameer K, Denny JC, Ding K, Jouni H, Crosslin DR, de Andrade M, Chute CG, Peissig P, Pacheco JA, Li R, Bastarache L, Kho AN, Ritchie MD, Masys DR, Chisholm RL, et al. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Human Genetics. 133: 95-109. PMID 24026423 DOI: 10.1007/S00439-013-1355-7 |
0.588 |
|
| 2014 |
Chang T, Yang W, Sara VDL, Kaste SC, Bowten EA, Basford M, Bastarache L, Roden DM, Denny JC, Mattano LA, Larsen EC, Winick NJ, Carroll WL, Cheng C, Pei D, et al. Glutamate Receptor Polymorphisms Contribute to Glucocorticoid-Associated Osteonecrosis Blood. 124: 367-367. DOI: 10.1182/Blood.V124.21.367.367 |
0.556 |
|
| 2013 |
Wei WQ, Mosley JD, Bastarache L, Denny JC. Validation and enhancement of a computable medication indication resource (MEDI) using a large practice-based dataset Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 2013: 1448-1456. PMID 24551419 |
0.415 |
|
| 2013 |
McPeek Hinz ER, Bastarache L, Denny JC. A natural language processing algorithm to define a venous thromboembolism phenotype. Amia ... Annual Symposium Proceedings. Amia Symposium. 2013: 975-83. PMID 24551388 |
0.454 |
|
| 2013 |
Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, et al. Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. Plos One. 8: e81503. PMID 24349080 DOI: 10.1371/Journal.Pone.0081503 |
0.44 |
|
| 2013 |
Wei WQ, Cronin RM, Xu H, Lasko TA, Bastarache L, Denny JC. Development of an ensemble resource linking MEDications to their Indications (MEDI). Amia Joint Summits On Translational Science Proceedings Amia Summit On Translational Science. 2013: 172. PMID 24303333 |
0.42 |
|
| 2013 |
Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nature Biotechnology. 31: 1102-10. PMID 24270849 DOI: 10.1038/Nbt.2749 |
0.626 |
|
| 2013 |
Wei WQ, Cronin RM, Xu H, Lasko TA, Bastarache L, Denny JC. Development and evaluation of an ensemble resource linking medications to their indications. Journal of the American Medical Informatics Association : Jamia. 20: 954-61. PMID 23576672 DOI: 10.1136/Amiajnl-2012-001431 |
0.472 |
|
| 2013 |
Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, et al. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation. 127: 1377-85. PMID 23463857 DOI: 10.1161/Circulationaha.112.000604 |
0.484 |
|
| 2012 |
Denny JC, Choma NN, Peterson JF, Miller RA, Bastarache L, Li M, Peterson NB. Natural language processing improves identification of colorectal cancer testing in the electronic medical record. Medical Decision Making : An International Journal of the Society For Medical Decision Making. 32: 188-97. PMID 21393557 DOI: 10.1177/0272989X11400418 |
0.463 |
|
| 2011 |
Denny JC, Crawford DC, Ritchie MD, Bielinski SJ, Basford MA, Bradford Y, Chai HS, Bastarache L, Zuvich R, Peissig P, Carrell D, Ramirez AH, Pathak J, Wilke RA, Rasmussen L, et al. Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. American Journal of Human Genetics. 89: 529-42. PMID 21981779 DOI: 10.1016/J.Ajhg.2011.09.008 |
0.586 |
|
| 2010 |
Doan S, Bastarache L, Klimkowski S, Denny JC, Xu H. Integrating existing natural language processing tools for medication extraction from discharge summaries. Journal of the American Medical Informatics Association : Jamia. 17: 528-31. PMID 20819857 DOI: 10.1136/Jamia.2010.003855 |
0.461 |
|
| 2010 |
Denny JC, Peterson JF, Choma NN, Xu H, Miller RA, Bastarache L, Peterson NB. Extracting timing and status descriptors for colonoscopy testing from electronic medical records. Journal of the American Medical Informatics Association : Jamia. 17: 383-8. PMID 20595304 DOI: 10.1136/Jamia.2010.004804 |
0.491 |
|
| 2010 |
Denny JC, Ritchie MD, Basford MA, Pulley JM, Bastarache L, Brown-Gentry K, Wang D, Masys DR, Roden DM, Crawford DC. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics (Oxford, England). 26: 1205-10. PMID 20335276 DOI: 10.1093/Bioinformatics/Btq126 |
0.584 |
|
| 2009 |
Denny JC, Peterson JF, Choma NN, Xu H, Miller RA, Bastarache L, Peterson NB. Development of a natural language processing system to identify timing and status of colonoscopy testing in electronic medical records. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 2009: 141. PMID 20351837 |
0.428 |
|
| 2009 |
Denny JC, Bastarache L, Sastre EA, Spickard A. Tracking medical students' clinical experiences using natural language processing. Journal of Biomedical Informatics. 42: 781-9. PMID 19236956 DOI: 10.1016/J.Jbi.2009.02.004 |
0.48 |
|
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