James Varani - Publications

Affiliations: 
Pathology University of Michigan School of Medicine 

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Aslam MN, McClintock SD, Rizvi AH, Attili D, Pandya S, Rehman H, Nadeem DM, Turgeon DK, Varani J. Abstract 657: The comparison of calcium-induced differentiation in colonoid cultures derived from the normal human colon tissue and colonic adenomas Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-657  0.303
2016 Cheng T, Yue M, Aslam MN, Wang X, Shekhawat G, Varani J, Schuger L. Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-β1 to -β3 Translation. The American Journal of Pathology. PMID 27939132 DOI: 10.1016/J.Ajpath.2016.10.004  0.609
2015 Dame MK, McClintock SD, Attili D, Simon B, Copley K, Finkbeiner S, Altheim C, Spence J, Appelman H, Turgeon DK, Samuelson LC, Brenner DE, Varani J. Abstract 322: Establishment and genomic characterization of enteroid cultures from human colonic adenomas and adenocarcinomas Cancer Research. 75: 322-322. DOI: 10.1158/1538-7445.Am2015-322  0.328
2014 McClintock SD, Dame MK, Aslam MN, Ali S, Knibbs RN, Warner RL, Varani J. Abstract 2666: Monoclonal antibodies specific for the oncofetal antigen - immature laminin receptor: Tumor selectivity, rapid internalization and in vivo efficacy Cancer Research. 74: 2666-2666. DOI: 10.1158/1538-7445.Am2014-2666  0.303
2013 Dame MK, Jiang Y, Turgeon DK, Appelman H, Aslam MN, Copley K, Attili D, Brenner DE, Varani J. Abstract 3711: Human colon mucosal crypts in culture: a model to assess colon chemoprevention. Cancer Research. 73: 3711-3711. DOI: 10.1158/1538-7445.Am2013-3711  0.369
2012 Varani J. Human skin organ culture for assessment of chemically induced skin damage. Expert Review of Dermatology. 7: 295-303. PMID 26989431 DOI: 10.1586/Edm.12.24  0.335
2012 Attili D, Jenkins B, Aslam MN, Dame MK, Varani J. Growth control in colon epithelial cells: gadolinium enhances calcium-mediated growth regulation. Biological Trace Element Research. 150: 467-76. PMID 23008064 DOI: 10.1007/S12011-012-9503-9  0.334
2012 Riser BL, Bhagavathula N, Perone P, Garchow K, Xu Y, Fisher GJ, Najmabadi F, Attili D, Varani J. Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis. Journal of Cell Communication and Signaling. 6: 97-105. PMID 22648571 DOI: 10.1007/S12079-012-0164-4  0.386
2012 Bleavins K, Perone P, Naik M, Rehman M, Aslam MN, Dame MK, Meshinchi S, Bhagavathula N, Varani J. Stimulation of fibroblast proliferation by insoluble gadolinium salts. Biological Trace Element Research. 145: 257-67. PMID 21882070 DOI: 10.1007/S12011-011-9176-9  0.345
2011 Zeng W, Tahrani A, Shakher J, Varani J, Hughes S, Dubb K, Stevens MJ. Effects of a synthetic retinoid on skin structure, matrix metalloproteinases, and procollagen in healthy and high-risk subjects with diabetes. Journal of Diabetes and Its Complications. 25: 398-404. PMID 22055260 DOI: 10.1016/J.Jdiacomp.2011.10.002  0.311
2011 Jenkins W, Perone P, Walker K, Bhagavathula N, Aslam MN, DaSilva M, Dame MK, Varani J. Fibroblast response to lanthanoid metal ion stimulation: potential contribution to fibrotic tissue injury. Biological Trace Element Research. 144: 621-35. PMID 21484406 DOI: 10.1007/S12011-011-9041-X  0.332
2011 Varani J. Calcium, calcium-sensing receptor and growth control in the colonic mucosa. Histology and Histopathology. 26: 769-79. PMID 21472691 DOI: 10.14670/Hh-26.769  0.335
2011 Dame MK, Veerapaneni I, Bhagavathula N, Naik M, Varani J. Human colon tissue in organ culture: calcium and multi-mineral-induced mucosal differentiation. In Vitro Cellular & Developmental Biology. Animal. 47: 32-8. PMID 21104039 DOI: 10.1007/S11626-010-9358-3  0.36
2010 Bhagavathula N, Dame MK, DaSilva M, Jenkins W, Aslam MN, Perone P, Varani J. Fibroblast response to gadolinium: Role for platelet-derived growth factor receptor Investigative Radiology. 45: 769-777. PMID 20714270 DOI: 10.1097/Rli.0B013E3181E943D2  0.392
2010 DaSilva M, O'Brien Deming M, Fligiel SE, Dame MK, Johnson KJ, Swartz RD, Varani J. Responses of human skin in organ culture and human skin fibroblasts to a gadolinium-based MRI contrast agent: comparison of skin from patients with end-stage renal disease and skin from healthy subjects. Investigative Radiology. 45: 733-9. PMID 20661146 DOI: 10.1097/Rli.0B013E3181E9436B  0.301
2010 Aslam MN, Warner RL, Bhagavathula N, Ginsburg I, Varani J. A multi-component herbal preparation (PADMA 28) improves structure/function of corticosteroid-treated skin, leading to improved wound healing of subsequently induced abrasion wounds in rats. Archives of Dermatological Research. 302: 669-77. PMID 20607545 DOI: 10.1007/S00403-010-1066-Z  0.357
2010 Perone PA, Weber SL, DaSilva M, Paruchuri T, Bhagavathula N, Aslam MN, Dame MK, Johnson KJ, Swartz RD, Varani J. Collagenolytic activity is suppressed in organ-cultured human skin exposed to a gadolinium-based MRI contrast agent. Investigative Radiology. 45: 42-8. PMID 19996758 DOI: 10.1097/Rli.0B013E3181Bf95Eb  0.371
2010 Dame MK, Bhagavathula N, Mankey C, Dasilva M, Paruchuri T, Aslam MN, Varani J. Human colon tissue in organ culture: Preservation of normal and neoplastic characteristics In Vitro Cellular and Developmental Biology - Animal. 46: 114-122. PMID 19915935 DOI: 10.1007/S11626-009-9247-9  0.378
2010 Varani J. Fibroblast aging: intrinsic and extrinsic factors Drug Discovery Today: Therapeutic Strategies. 7: 65-70. DOI: 10.1016/J.Ddstr.2011.06.001  0.348
2009 Bhagavathula N, Warner RL, DaSilva M, McClintock SD, Barron A, Aslam MN, Johnson KJ, Varani J. A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 17: 360-6. PMID 19660044 DOI: 10.1111/J.1524-475X.2009.00483.X  0.306
2009 Bhagavathula N, DaSilva M, Aslam MN, Dame MK, Warner RL, Xu Y, Fisher GJ, Johnson KJ, Swartz R, Varani J. Regulation of collagen turnover in human skin fibroblasts exposed to a gadolinium-based contrast agent. Investigative Radiology. 44: 433-9. PMID 19561517 DOI: 10.1097/Rli.0B013E3181A4D7E9  0.356
2009 Dame MK, Paruchuri T, Dasilva M, Bhagavathula N, Ridder W, Varani J. The Göttingen minipig for assessment of retinoid efficacy in the skin: Comparison of results from topically treated animals with results from organ-cultured skin In Vitro Cellular and Developmental Biology - Animal. 45: 551-557. PMID 19536603 DOI: 10.1007/S11626-009-9221-6  0.374
2009 Aslam MN, Bhagavathula N, Paruchuri T, Hu X, Chakrabarty S, Varani J. Growth-inhibitory effects of a mineralized extract from the red marine algae, Lithothamnion calcareum, on Ca(2+)-sensitive and Ca(2+)-resistant human colon carcinoma cells. Cancer Letters. 283: 186-92. PMID 19394137 DOI: 10.1016/J.Canlet.2009.03.037  0.302
2009 Varani J, Perone P, Deming MO, Warner RL, Aslam MN, Bhagavathula N, Dame MK, Voorhees JJ. Impaired keratinocyte function on matrix metalloproteinase-1 (MMP-1) damaged collagen. Archives of Dermatological Research. 301: 497-506. PMID 19352688 DOI: 10.1007/S00403-009-0948-4  0.399
2009 Fisher GJ, Quan T, Purohit T, Shao Y, Cho MK, He T, Varani J, Kang S, Voorhees JJ. Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. The American Journal of Pathology. 174: 101-14. PMID 19116368 DOI: 10.2353/Ajpath.2009.080599  0.368
2009 Varani J, DaSilva M, Warner RL, Deming MO, Barron AG, Johnson KJ, Swartz RD. Effects of gadolinium-based magnetic resonance imaging contrast agents on human skin in organ culture and human skin fibroblasts. Investigative Radiology. 44: 74-81. PMID 19077912 DOI: 10.1097/Rli.0B013E31818F76B5  0.405
2009 Liu G, Hu X, Varani J, Chakrabarty S. Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: promotion of cytotoxic response to mitomycin C and fluorouracil. Molecular Carcinogenesis. 48: 202-11. PMID 18618519 DOI: 10.1002/Mc.20470  0.346
2008 Dame MK, Varani J. Recombinant collagen for animal product-free dextran microcarriers. In Vitro Cellular & Developmental Biology. Animal. 44: 407-14. PMID 18815845 DOI: 10.1007/S11626-008-9139-4  0.411
2008 Dame MK, Spahlinger DM, DaSilva M, Perone P, Dunstan R, Varani J. Establishment and characteristics of Gottingen minipig skin in organ culture and monolayer cell culture: Relevance to drug safety testing In Vitro Cellular and Developmental Biology - Animal. 44: 245-252. PMID 18568375 DOI: 10.1007/S11626-008-9091-3  0.398
2008 Fisher GJ, Varani J, Voorhees JJ. Looking older: fibroblast collapse and therapeutic implications. Archives of Dermatology. 144: 666-72. PMID 18490597 DOI: 10.1001/Archderm.144.5.666  0.355
2008 Warner RL, Bhagavathula N, Nerusu K, Hanosh A, McClintock SD, Naik MK, Johnson KJ, Ginsburg I, Varani J. MDI 301, a nonirritating retinoid, improves abrasion wound healing in damaged/atrophic skin. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 16: 117-24. PMID 18211583 DOI: 10.1111/J.1524-475X.2007.00338.X  0.378
2008 Bhagavathula N, Nerusu KC, Hanosh A, Aslam MN, Sundberg TB, Opipari AW, Johnson K, Kang S, Glick GD, Varani J. 7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (Bz-423), a benzodiazepine, suppresses keratinocyte proliferation and has antipsoriatic activity in the human skin-severe, combined immunodeficient mouse transplant model. The Journal of Pharmacology and Experimental Therapeutics. 324: 938-47. PMID 18055879 DOI: 10.1124/Jpet.107.130955  0.421
2008 Varani J, Bhagavathula N, Aslam MN, Fay K, Warner RL, Hanosh A, Barron AG, Miller RA. Inhibition of retinoic acid-induced skin irritation in calorie-restricted mice. Archives of Dermatological Research. 300: 27-35. PMID 17968574 DOI: 10.1007/S00403-007-0797-Y  0.356
2008 Ward PA, Varani J. Mechanisms of neutrophil-mediated injury. Clinical and Experimental Immunology. 93: 2-2. PMID 8365020 DOI: 10.1111/J.1365-2249.1993.Tb06211.X  0.335
2007 Varani J, Perone P, Spahlinger DM, Singer LM, Diegel KL, Bobrowski WF, Dunstan R. Human skin in organ culture and human skin cells (keratinocytes and fibroblasts) in monolayer culture for assessment of chemically induced skin damage. Toxicologic Pathology. 35: 693-701. PMID 17763283 DOI: 10.1080/01926230701481907  0.386
2007 Bhagavathula N, Hanosh AW, Nerusu KC, Appelman H, Chakrabarty S, Varani J. Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function. International Journal of Cancer. Journal International Du Cancer. 121: 1455-62. PMID 17557293 DOI: 10.1002/Ijc.22858  0.347
2007 Nerusu KC, Warner RL, Bhagavathula N, McClintock SD, Johnson KJ, Varani J. Matrix metalloproteinase-3 (stromelysin-1) in acute inflammatory tissue injury. Experimental and Molecular Pathology. 83: 169-76. PMID 17540368 DOI: 10.1016/J.Yexmp.2007.04.003  0.305
2007 Kafi R, Kwak HS, Schumacher WE, Cho S, Hanft VN, Hamilton TA, King AL, Neal JD, Varani J, Fisher GJ, Voorhees JJ, Kang S. Improvement of naturally aged skin with vitamin A (retinol). Archives of Dermatology. 143: 606-12. PMID 17515510 DOI: 10.1001/Archderm.143.5.606  0.303
2007 Reichrath J, Lehmann B, Carlberg C, Varani J, Zouboulis CC. Vitamins as hormones. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 39: 71-84. PMID 17326003 DOI: 10.1055/S-2007-958715  0.312
2007 Wang F, Garza LA, Kang S, Varani J, Orringer JS, Fisher GJ, Voorhees JJ. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Archives of Dermatology. 143: 155-63. PMID 17309996 DOI: 10.1001/Archderm.143.2.155  0.32
2007 Varani J, Fay K, Perone P. MDI 301, a non-irritating retinoid, induces changes in human skin that underlie repair Archives of Dermatological Research. 298: 439-448. PMID 17146625 DOI: 10.1007/S00403-006-0720-Y  0.387
2007 Varani J. Control of normal and abnormal proliferation in the epidermis: EGF receptor function and epidermal hyperplasia Expert Review of Dermatology. 2: 629-638. DOI: 10.1586/17469872.2.5.629  0.358
2007 Barron AG, Warner RL, Bhagavathula N, Dasilva M, Johnson KJ, Varani J. Members of the Family Zingiberaceae Promote Tropoelastin and Procollagen Type 1 Synthesis in Cultured Human Fibroblasts The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.6.A760  0.32
2006 Varani J, Bhagavathula N, Ellis CN, Pershadsingh HA. Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease. Expert Opinion On Investigational Drugs. 15: 1453-68. PMID 17040203 DOI: 10.1517/13543784.15.11.1453  0.379
2006 Varani J, Dame MK, Rittie L, Fligiel SE, Kang S, Fisher GJ, Voorhees JJ. Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. The American Journal of Pathology. 168: 1861-8. PMID 16723701 DOI: 10.2353/Ajpath.2006.051302  0.353
2006 Rittié L, Varani J, Kang S, Voorhees JJ, Fisher GJ. Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo. The Journal of Investigative Dermatology. 126: 732-9. PMID 16470170 DOI: 10.1038/Sj.Jid.5700202  0.354
2006 Aslam MN, Lansky EP, Varani J. Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of Ethnopharmacology. 103: 311-8. PMID 16221534 DOI: 10.1016/J.Jep.2005.07.027  0.361
2005 Bhagavathula N, Kelley EA, Reddy M, Nerusu KC, Leonard C, Fay K, Chakrabarty S, Varani J. Upregulation of calcium-sensing receptor and mitogen-activated protein kinase signalling in the regulation of growth and differentiation in colon carcinoma. British Journal of Cancer. 93: 1364-71. PMID 16278666 DOI: 10.1038/Sj.Bjc.6602852  0.342
2005 Bhagavathula N, Nerusu KC, Reddy M, Ellis CN, Chittiboyina A, Avery M, Pershadsingh HA, Kurtz TW, Varani J. BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. The Journal of Pharmacology and Experimental Therapeutics. 315: 996-1004. PMID 16109743 DOI: 10.1124/Jpet.105.091066  0.615
2005 Monhian N, Jewett BS, Baker SR, Varani J. Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients. Archives of Facial Plastic Surgery. 7: 238-43. PMID 16027344 DOI: 10.1001/Archfaci.7.4.238  0.368
2005 Yucel T, Mutnal A, Fay K, Fligiel SE, Wang T, Johnson T, Baker SR, Varani J. Matrix metalloproteinase expression in basal cell carcinoma: relationship between enzyme profile and collagen fragmentation pattern. Experimental and Molecular Pathology. 79: 151-60. PMID 16004981 DOI: 10.1016/J.Yexmp.2005.05.003  0.333
2005 Varani J, Lateef H, Fay K, Elder JT. Antagonism of epidermal growth factor receptor tyrosine kinase ameliorates the psoriatic phenotype in organ-cultured skin Skin Pharmacology and Physiology. 18: 123-131. PMID 15897684 DOI: 10.1159/000084909  0.396
2005 Bhagavathula N, Nerusu KC, Fisher GJ, Liu G, Thakur AB, Gemmell L, Kumar S, Xu ZH, Hinton P, Tsurushita N, Landolfi NF, Voorhees JJ, Varani J. Amphiregulin and epidermal hyperplasia: amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice. The American Journal of Pathology. 166: 1009-16. PMID 15793282 DOI: 10.1016/S0002-9440(10)62322-X  0.366
2005 Aslam MN, Fligiel H, Lateef H, Fisher GJ, Ginsburg I, Varani J. PADMA 28: a multi-component herbal preparation with retinoid-like dermal activity but without epidermal effects. The Journal of Investigative Dermatology. 124: 524-9. PMID 15737192 DOI: 10.1111/J.0022-202X.2004.23596.X  0.423
2005 Varani J, Bhagavathula N, Nerusu KC, Sherzer H, Fay K, Boitano AE, Glick GD, Johnson K, Kang S, Opipari AW. A novel benzodiazepine selectively inhibits keratinocyte proliferation and reduces retinoid-induced epidermal hyperplasia in organ-cultured human skin. The Journal of Pharmacology and Experimental Therapeutics. 313: 56-63. PMID 15576471 DOI: 10.1124/Jpet.104.075929  0.404
2005 Murphy HS, Varani J, Ward PA. Chapter 12 Endothelial cell injury and defense Advances in Molecular and Cell Biology. 35: 335-364. DOI: 10.1016/S1569-2558(05)35012-0  0.355
2004 Warner RL, Lukacs NW, Shapiro SD, Bhagarvathula N, Nerusu KC, Varani J, Johnson KJ. Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen. The American Journal of Pathology. 165: 1921-30. PMID 15579436 DOI: 10.1016/S0002-9440(10)63244-0  0.322
2004 Appleyard VC, O'Neill MA, Murray KE, Bray SE, Thomson G, Kernohan NM, Varani J, Zhang J, Thompson AM. Activity of MDI-301, a novel synthetic retinoid, in xenografts. Anti-Cancer Drugs. 15: 991-6. PMID 15514569 DOI: 10.1097/00001813-200411000-00009  0.302
2004 Varani J, Kelley EA, Perone P, Lateef H. Retinoid-induced epidermal hyperplasia in human skin organ culture: inhibition with soy extract and soy isoflavones. Experimental and Molecular Pathology. 77: 176-83. PMID 15507233 DOI: 10.1016/J.Yexmp.2004.08.003  0.361
2004 Varani J. Epithelial cell invasion of the stroma in human skin organ culture. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2989-95. PMID 15353331 DOI: 10.2741/1453  0.438
2004 Warner RL, Winter HC, Speyer CL, Varani J, Oldstein IJ, Murphy HS, Johnson KJ. Marasmius oreades lectin induces renal thrombotic microangiopathic lesions. Experimental and Molecular Pathology. 77: 77-84. PMID 15351229 DOI: 10.1016/J.Yexmp.2004.04.003  0.31
2004 Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz TW, Benson SC. Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Archives of Dermatological Research. 296: 97-104. PMID 15221328 DOI: 10.1007/S00403-004-0480-5  0.601
2004 Lateef H, Stevens MJ, Varani J. All-trans-retinoic acid suppresses matrix metalloproteinase activity and increases collagen synthesis in diabetic human skin in organ culture. The American Journal of Pathology. 165: 167-74. PMID 15215172 DOI: 10.1016/S0002-9440(10)63285-3  0.358
2004 Varani J, Schuger L, Dame MK, Leonard C, Fligiel SE, Kang S, Fisher GJ, Voorhees JJ. Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin. The Journal of Investigative Dermatology. 122: 1471-9. PMID 15175039 DOI: 10.1111/J.0022-202X.2004.22614.X  0.686
2004 Warner RL, Bhagavathula N, Nerusu KC, Lateef H, Younkin E, Johnson KJ, Varani J. Matrix metalloproteinases in acute inflammation: induction of MMP-3 and MMP-9 in fibroblasts and epithelial cells following exposure to pro-inflammatory mediators in vitro. Experimental and Molecular Pathology. 76: 189-95. PMID 15126100 DOI: 10.1016/J.Yexmp.2004.01.003  0.386
2004 Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, Ho CI, Benson SC, Pershadsingh HA, Kurtz TW, Varani J. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. The Journal of Investigative Dermatology. 122: 130-9. PMID 14962101 DOI: 10.1046/J.0022-202X.2003.22111.X  0.635
2003 Brennan M, Bhatti H, Nerusu KC, Bhagavathula N, Kang S, Fisher GJ, Varani J, Voorhees JJ. Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochemistry and Photobiology. 78: 43-8. PMID 12929747 DOI: 10.1562/0031-8655(2003)078<0043:Mmitmc>2.0.Co;2  0.367
2003 Hattori Y, Nerusu KC, Bhagavathula N, Brennan M, Hattori N, Murphy HS, Su LD, Wang TS, Johnson TM, Varani J. Vascular expression of matrix metalloproteinase-13 (collagenase-3) in basal cell carcinoma. Experimental and Molecular Pathology. 74: 230-7. PMID 12782009 DOI: 10.1016/S0014-4800(03)00014-5  0.417
2003 Fligiel SE, Varani J, Datta SC, Kang S, Fisher GJ, Voorhees JJ. Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro. The Journal of Investigative Dermatology. 120: 842-8. PMID 12713591 DOI: 10.1046/J.1523-1747.2003.12148.X  0.36
2003 Knibbs RN, Dame M, Allen MR, Ding Y, Hillegas WJ, Varani J, Stoolman LM. Sustained high-yield production of recombinant proteins in transiently transfected COS-7 cells grown on trimethylamine-coated (hillex) microcarrier beads. Biotechnology Progress. 19: 9-13. PMID 12573000 DOI: 10.1021/Bp020092R  0.369
2002 Varani J, Perone P, Merfert MG, Moon SE, Larkin D, Stevens MJ. All-trans retinoic acid improves structure and function of diabetic rat skin in organ culture. Diabetes. 51: 3510-6. PMID 12453908 DOI: 10.2337/Diabetes.51.12.3510  0.374
2002 Moon SE, Bhagavathula N, Varani J. Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events. British Journal of Cancer. 87: 457-464. PMID 12177784 DOI: 10.1038/Sj.Bjc.6600478  0.346
2002 Varani J, Perone P, Fligiel SE, Fisher GJ, Voorhees JJ. Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis. The Journal of Investigative Dermatology. 119: 122-9. PMID 12164934 DOI: 10.1046/J.1523-1747.2002.01810.X  0.352
2002 Varani J, Petryniak J, Takagaki M, Dame MK, Petryniak B, Goldstein IJ. Differential expression of an alpha-galactosyl-containing trisaccharide on high- and low-malignant murine sarcoma cells: identification and regulation. Clinical & Experimental Metastasis. 19: 1-8. PMID 11918078 DOI: 10.1023/A:1013865411941  0.341
2001 Varani J, Zeigler M, Dame MK, Kang S, Fisher GJ, Voorhees JJ, Stoll SW, Elder JT. Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors Mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy. Journal of Investigative Dermatology. 117: 1335-1341. PMID 11886492 DOI: 10.1046/J.0022-202X.2001.01564.X  0.373
2001 Moon SE, Dame MK, Remick DR, Elder JT, Varani J. Induction of matrix metalloproteinase-1 (MMP-1) during epidermal invasion of the stroma in human skin organ culture: keratinocyte stimulation of fibroblast MMP-1 production. British Journal of Cancer. 85: 1600-1605. PMID 11720451 DOI: 10.1054/Bjoc.2001.2122  0.355
2001 Zeigler M, Chi Y, Tumas DB, Bodary S, Tang H, Varani J. Anti-CD11a ameliorates disease in the human psoriatic skin-SCID mouse transplant model : Comparison of antibody to CD11a with cyclosporin A and clobetasol propionate Laboratory Investigation. 81: 1253-1261. PMID 11555673 DOI: 10.1038/Labinvest.3780339  0.333
2001 Varani J, Hattori Y, Dame MK, Schmidt T, Murphy HS, Johnson KJ, Wojno KJ. Matrix metalloproteinases (MMPs) in fresh human prostate tumour tissue and organ-cultured prostate tissue: levels of collagenolytic and gelatinolytic MMPs are low, variable and different in fresh tissue versus organ-cultured tissue. British Journal of Cancer. 84: 1076-1083. PMID 11308257 DOI: 10.1054/Bjoc.2000.1712  0.357
2001 Varani J, Spearman D, Perone P, Fligiel SEG, Datta SC, Wang ZQ, Shao Y, Kang S, Fisher GJ, Voorhees JJ. Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro American Journal of Pathology. 158: 931-942. PMID 11238041 DOI: 10.1016/S0002-9440(10)64040-0  0.377
2001 Riser BL, Varani J, Cortes P, Yee J, Dame M, Sharba AK. Cyclic stretching of mesangial cells up-regulates intercellular adhesion molecule-1 and leukocyte adherence: a possible new mechanism for glomerulosclerosis. American Journal of Pathology. 158: 11-17. PMID 11141473 DOI: 10.1016/S0002-9440(10)63938-7  0.326
2000 Warner RL, Bless NM, Lewis CS, Younkin E, Beltran L, Guo R, Johnson KJ, Varani J. Time-dependent inhibition of immune complex-induced lung injury by catalase: relationship to alterations in macrophage and neutrophil matrix metalloproteinase elaboration. Free Radical Biology & Medicine. 29: 8-16. PMID 10962200 DOI: 10.1016/S0891-5849(00)00282-3  0.323
2000 Chung JH, Kang S, Varani J, Lin J, Fisher GJ, Voorhees JJ. Decreased Extracellular-Signal-Regulated Kinase and Increased Stress-Activated MAP Kinase Activities in Aged Human Skin In Vivo Journal of Investigative Dermatology. 115: 177-182. PMID 10951233 DOI: 10.1046/J.1523-1747.2000.00009.X  0.33
2000 Ellis CN, Varani J, Fisher GJ, Zeigler ME, Pershadsingh HA, Benson SC, Chi Y, Kurtz TW. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Archives of Dermatology. 136: 609-16. PMID 10815854 DOI: 10.1001/Archderm.136.5.609  0.331
2000 Varani J, Warner RL, Gharaee-Kermani M, Phan SH, Kang S, Chung JH, Wang ZQ, Datta SC, Fisher GJ, Voorhees JJ. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. The Journal of Investigative Dermatology. 114: 480-6. PMID 10692106 DOI: 10.1046/J.1523-1747.2000.00902.X  0.362
2000 Varani J, Hattori Y, Chi Y, Schmidt T, Perone P, Zeigler ME, Fader DJ, Johnson TM. Collagenolytic and gelatinolytic matrix metalloproteinases and their inhibitors in basal cell carcinoma of skin: comparison with normal skin British Journal of Cancer. 82: 657-665. PMID 10682680 DOI: 10.1054/Bjoc.1999.0978  0.358
1999 Ginsburg I, Sadovnik M, Sallon S, Milo-Goldzweig I, Mechoulam R, Breuer A, Gibbs D, Varani J, Roberts S, Cleator E, Singh N. PADMA-28, a traditional tibetan herbal preparation inhibits the respiratory burst in human neutrophils, the killing of epithelial cells by mixtures of oxidants and pro-inflammatory agonists and peroxidation of lipids. Inflammopharmacology. 7: 47-62. PMID 17657446 DOI: 10.1007/S10787-999-0025-9  0.376
1999 Tavakkol A, Varani J, Elder JT, Zouboulis CC. Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor. Archives of Dermatological Research. 291: 643-51. PMID 10651165 DOI: 10.1007/S004030050469  0.358
1999 Ginsburg I, Ward PA, Varani J. Can we learn from the pathogenetic strategies of group A hemolytic streptococci how tissues are injured and organs fail in post-infectious and inflammatory sequelae? Fems Immunology and Medical Microbiology. 25: 325-38. PMID 10497863 DOI: 10.1111/J.1574-695X.1999.Tb01357.X  0.331
1999 Murphy HS, Warner RL, Bakopoulos N, Dame MK, Varani J, Ward PA. Endothelial cell determinants of susceptibility to neutrophil-mediated killing. Shock (Augusta, Ga.). 12: 111-7. PMID 10446891 DOI: 10.1097/00024382-199908000-00004  0.371
1999 Zeigler ME, Chi Y, Schmidt T, Varani J. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor‐stimulated human epidermal keratinocytes Journal of Cellular Physiology. 180: 271-284. PMID 10395297 DOI: 10.1002/(Sici)1097-4652(199908)180:2<271::Aid-Jcp15>3.0.Co;2-D  0.38
1999 Gibbs DF, Shanley TP, Warner RL, Murphy HS, Varani J, Johnson KJ. Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury. Evidence for alveolar macrophage as source of proteinases. American Journal of Respiratory Cell and Molecular Biology. 20: 1145-54. PMID 10340933 DOI: 10.1165/Ajrcmb.20.6.3482  0.33
1999 Gibbs DF, Warner RL, Weiss SJ, Johnson KJ, Varani J. Characterization of matrix metalloproteinases produced by rat alveolar macrophages. American Journal of Respiratory Cell and Molecular Biology. 20: 1136-44. PMID 10340932 DOI: 10.1165/Ajrcmb.20.6.3483  0.328
1998 Varani J, Piel F, Josephs S, Beals TF, Hillegas WJ. Attachment and growth of anchorage-dependent cells on a novel, charged-surface microcarrier under serum-free conditions. Cytotechnology. 28: 101-9. PMID 19003412 DOI: 10.1023/A:1008029715765  0.317
1998 Chi Y, Zeigler ME, Walker J, Perone P, Datta SC, Varani J. Elaboration of matrix metalloproteinase inhibitors by human skin in organ culture and by skin cells in monolayer culture: relationship to invasion. Invasion & Metastasis. 18: 27-34. PMID 10207248 DOI: 10.1159/000024496  0.375
1998 Murphy HS, Bakopoulos N, Dame MK, Varani J, Ward PA. Heterogeneity of Vascular Endothelial Cells: Differences in Susceptibility to Neutrophil-mediated Injury Microvascular Research. 56: 203-211. PMID 9828158 DOI: 10.1006/Mvre.1998.2110  0.366
1998 Varani J, Kang S, Stoll S, Elder JT. Human Psoriatic Skin in Organ Culture: Comparison with Normal Skin Exposed to Exogenous Growth Factors and Effects of an Antibody to the EGF Receptor Pathobiology. 66: 253-259. PMID 9769471 DOI: 10.1159/000028031  0.357
1998 Varani J. Preservation of human skin structure and function in organ culture Histology and Histopathology. 13: 775-783. PMID 9690135 DOI: 10.14670/Hh-13.775  0.383
1998 Varani J, Fisher GJ, Kang S, Voorhees JJ. Molecular Mechanisms of Intrinsic Skin Aging and Retinoid-Induced Repair and Reversal Journal of Investigative Dermatology. 3: 57-60. DOI: 10.1038/Jidsymp.1998.14  0.378
1998 Varani J, Warner R, Kang S, Fisher GJ, Voorhees JJ. Collagen I and collagen III expression in young and old skin: Effects of topical retinol treatment of 80+ year old individuals Journal of Dermatological Science. 16. DOI: 10.1016/S0923-1811(98)83762-6  0.311
1998 Chung J, Lin J, Varani J, Kang S, Fisher G, Voorhees J. Increased stress-activated and decreased growth factor-activated map kinase activities lead to collagen deficiency and reduced cell growth in skin of elderly persons Journal of Dermatological Science. 16. DOI: 10.1016/S0923-1811(98)83717-1  0.328
1997 Fisher GJ, Wang ZQ, Datta SC, Varani J, Kang S, Voorhees JJ. Pathophysiology of premature skin aging induced by ultraviolet light The New England Journal of Medicine. 337: 1419-1428. PMID 9358139 DOI: 10.1056/Nejm199711133372003  0.322
1997 Ginsburg I, Yedgar S, Varani J. Diethyldithiocarbamate and nitric oxide synergize with oxidants and with membrane-damaging agents to injure mammalian cells. Free Radical Research. 27: 143-64. PMID 9350419 DOI: 10.3109/10715769709097847  0.31
1997 Varani J, Zeigler ME, Perone P, Carey TE, Datta SC. Human squamous carcinoma cell invasion in organ-cultured skin. Cancer Letters. 111: 51-7. PMID 9022127 DOI: 10.1016/S0304-3835(96)04492-8  0.414
1996 Varani J, Josephs S, Hillegas WJ. Human diploid fibroblast growth on polystyrene microcarriers in aggregates Cytotechnology. 22: 111-117. PMID 22358921 DOI: 10.1007/Bf00353930  0.374
1996 Varani J, Hirschl RB, Dame M, Johnson K. Perfluorocarbon protects lung epithelial cells from neutrophil-mediated injury in an in vitro model of liquid ventilation therapy Shock. 6: 339-344. PMID 8946649 DOI: 10.1097/00024382-199611000-00007  0.378
1996 Varani J, Dame MK, Diaz M, Stoolman L. Deferoxamine interferes with adhesive functions of activated human neutrophils. Shock. 5: 395-401. PMID 8799950 DOI: 10.1097/00024382-199606000-00002  0.405
1996 Fisher GJ, Datta SC, Talwar HS, Wang ZQ, Varani J, Kang S, Voorhees JJ. Molecular basis of sun-induced premature skin ageing and retinoid antagonism Nature. 379: 335-339. PMID 8552187 DOI: 10.1038/379335A0  0.333
1995 Varani J, Dame MK. Injury to adult human dermal microvascular endothelial cells in vitro. Shock. 3: 179-183. PMID 7773796 DOI: 10.1097/00024382-199503000-00004  0.343
1995 McKeever PE, Varani J, Papadopoulos SM, Wang M, McCoy JP. Products of cells from gliomas: IX. Evidence that two fundamentally different mechanisms change extracellular matrix expression by gliomas. Journal of Neuro-Oncology. 24: 267-80. PMID 7595757 DOI: 10.1007/Bf01052843  0.395
1995 Varani J, Fligiel SE, Inman DR, Beals TF, Hillegas WJ. Modulation of adhesive properties of DEAE-dextran with laminin. Journal of Biomedical Materials Research. 29: 993-7. PMID 7593043 DOI: 10.1002/Jbm.820290811  0.417
1995 Song Z, Varani J, Goldstein IJ. Expression and Function of β1 Integrins on Adherent and Nonadherent Ehrlich Ascites Tumor Cells Experimental Cell Research. 218: 96-104. PMID 7537699 DOI: 10.1006/Excr.1995.1135  0.383
1994 Varani J, Perone P, Griffiths CE, Inman DR, Fligiel SE, Voorhees JJ. All-trans retinoic acid (RA) stimulates events in organ-cultured human skin that underlie repair. Adult skin from sun-protected and sun-exposed sites responds in an identical manner to RA while neonatal foreskin responds differently. The Journal of Clinical Investigation. 94: 1747-56. PMID 7962521 DOI: 10.1172/Jci117522  0.377
1994 Huang S, Varani J, Chakrabarty S. Control of AKR fibroblast phenotype by fibronectin: regulation of cell-surface fibronectin binding receptor by fibronectin. Journal of Cellular Physiology. 161: 470-82. PMID 7962129 DOI: 10.1002/Jcp.1041610310  0.355
1994 Shumaker DK, Sklar MD, Prochownik EV, Varani J. Increased cell-substrate adhesion accompanies conditional reversion to the normal phenotype in ras-oncogene-transformed NIH-3T3 cells Experimental Cell Research. 214: 440-446. PMID 7925639 DOI: 10.1006/Excr.1994.1280  0.348
1994 Varani J, Perone P, Fligiel SE, Inman DR, Voorhees JJ. all-trans-retinoic acid preserves viability of fibroblasts and keratinocytes in full-thickness human skin and fibroblasts in isolated dermis in organ culture. Archives of Dermatological Research. 286: 443-7. PMID 7864657 DOI: 10.1007/Bf00371569  0.361
1994 Varani J, Ward PA. Mechanisms Of Endothelial Cell Injury In Acute Inflammation Shock. 2: 311-312. PMID 7743355 DOI: 10.1097/00024382-199411000-00001  0.306
1993 Stoolman LM, Wang T, Situ R, Varani J. Regulation of fibronectin and laminin binding activity in cultured human lymphoblastic cell lines. Journal of Cellular Physiology. 154: 593-600. PMID 8436606 DOI: 10.1002/Jcp.1041540318  0.323
1993 Situ R, Inman DR, Fligiel SE, Varani J. Effects of all-trans-retinoic acid on melanocyte adhesion and motility. Dermatology (Basel, Switzerland). 186: 38-44. PMID 8435515 DOI: 10.1159/000247300  0.346
1993 Schuger L, Varani J, Mitra R, Gilbride K. Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor receptors. Developmental Biology. 159: 462-73. PMID 8405671 DOI: 10.1006/Dbio.1993.1256  0.67
1993 Ginsburg I, Varani J. Interaction of viable group A streptococci and hydrogen peroxide in killing of vascular endothelial cells. Free Radical Biology & Medicine. 14: 495-500. PMID 8349139 DOI: 10.1016/0891-5849(93)90106-5  0.336
1993 Ginsburg I, Mitra RS, Gibbs DF, Varani J, Kohen R. Killing of endothelial cells and release of arachidonic acid. Synergistic effects among hydrogen peroxide, membrane-damaging agents, cationic substances, and proteinases and their modulation by inhibitors. Inflammation. 17: 295-319. PMID 8330929 DOI: 10.1007/Bf00918992  0.359
1993 Varani J, Fligiel SE, Perone P, Inman DR, Voorhees JJ. Effects of sodium lauryl sulfate on human skin in organ culture: comparison with all-trans-retinoic acid and epidermal growth factor. Dermatology (Basel, Switzerland). 187: 19-25. PMID 8324272 DOI: 10.1159/000247191  0.356
1993 Song Z, Varani J, Goldstein IJ. Differences in cell surface carbohydrates, and in laminin and fibronectin synthesis, between adherent and non-adherent Ehrlich ascites tumor cells International Journal of Cancer. 55: 1029-1035. PMID 8253521 DOI: 10.1002/Ijc.2910550625  0.388
1993 Varani J, Inman DR, Perone P, Fligiel SE, Voorhees JJ. Retinoid toxicity for fibroblasts and epithelial cells is separable from growth promoting activity. The Journal of Investigative Dermatology. 101: 839-42. PMID 8245512 DOI: 10.1111/1523-1747.Ep12371704  0.387
1993 Mulligan MS, Desrochers PE, Chinnaiyan AM, Gibbs DF, Varani J, Johnson KJ, Weiss SJ. In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2 Proceedings of the National Academy of Sciences of the United States of America. 90: 11523-11527. PMID 7903451 DOI: 10.1073/Pnas.90.24.11523  0.341
1993 Varani J, Inman DR, Fligiel SE, Hillegas WJ. Use of recombinant and synthetic peptides as attachment factors for cells on microcarriers. Cytotechnology. 13: 89-98. PMID 7764582 DOI: 10.1007/Bf00749935  0.302
1993 Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K. Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 195: 43-54. PMID 1292752 DOI: 10.1002/Aja.1001950105  0.661
1992 Varani J, Inman DR, Gibbs DF, Fligiel SE, Voorhees JJ. Modulation of Ca2+ levels in keratinocytes by all-trans retinoic acid. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 60: 93-9. PMID 1571097 DOI: 10.1159/000163705  0.32
1992 Fligiel SE, Inman DR, Talwar HS, Fisher GJ, Voorhees JJ, Varani J. Modulation of growth in normal and malignant melanocytic cells by all-trans retinoic acid. Journal of Cutaneous Pathology. 19: 27-33. PMID 1556264 DOI: 10.1111/J.1600-0560.1992.Tb01555.X  0.35
1992 Huber AR, Ellis S, Johnson KJ, Dixit VM, Varani J. Monocyte diapedesis through an in vitro vessel wall construct: inhibition with monoclonal antibodies to thrombospondin. Journal of Leukocyte Biology. 52: 524-8. PMID 1431563 DOI: 10.1002/Jlb.52.5.524  0.355
1992 Ginsburg I, Misgav R, Pinson A, Varani J, Ward PA, Kohen R. Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines. Inflammation. 16: 519-38. PMID 1428126 DOI: 10.1007/Bf00918977  0.402
1992 Varani J, Sitrin RG, Hillegas W. Expression of plasminogen activator and plasminogen activator inhibitor mRNA in human fibroblasts grown on different substrates. Cytotechnology. 9: 157-162. PMID 1369169 DOI: 10.1007/Bf02521743  0.351
1992 Varani J, Taylor CG, Riser B, Shumaker DK, Yeh KY, Dame M, Gibbs DF, Todd RF, Dumler F, Bromberg J, Killen PD. Mesangial cell killing by leukocytes: role of leukocyte oxidants and proteolytic enzymes. Kidney International. 42: 1169-1177. PMID 1360554 DOI: 10.1038/Ki.1992.401  0.361
1992 Ginsburg I, Misgav R, Samuni A, Gibbs DF, Varani J, Kohen R. Human neutrophils stimulated by cetyltrimethyl ammonium bromide generate luminol-amplified and non-amplified chemiluminescence but no superoxide production: A paradox Inflammopharmacology. 1: 337-351. DOI: 10.1007/Bf02755884  0.304
1991 Ward PA, Warren JS, Varani J, Johnson KJ. PAF, cytokines, toxic oxygen products and cell injury. Molecular Aspects of Medicine. 12: 169-174. PMID 2072825 DOI: 10.1016/0098-2997(91)90012-B  0.376
1991 Varani J, Stoolman L, Wang T, Schuger L, Flippen C, Dame M, Johnson KJ, Todd RF, Ryan US, Ward PA. Thrombospondin production and thrombospondin-mediated adhesion in U937 cells. Experimental Cell Research. 195: 177-82. PMID 2055266 DOI: 10.1016/0014-4827(91)90514-U  0.66
1991 Shayevitz JR, Varani J, Ward PA, Knight PR. Halothane and isoflurane increase pulmonary artery endothelial cell sensitivity to oxidant-mediated injury Anesthesiology. 74: 1067-1077. PMID 2042760 DOI: 10.1097/00000542-199106000-00015  0.358
1991 Castle V, Varani J, Fligiel S, Prochownik EV, Dixit V. Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma. Journal of Clinical Investigation. 87: 1883-1888. PMID 2040684 DOI: 10.1172/Jci115212  0.358
1991 Varani J, Schuger L, Fligiel SE, Inman DR, Chakrabarty S. Production of fibronectin by human tumor cells and interaction with exogenous fibronectin: comparison of cell lines obtained from colon adenocarcinomas and squamous carcinomas of the upper aerodigestive tract. International Journal of Cancer. Journal International Du Cancer. 47: 421-5. PMID 1993550 DOI: 10.1002/Ijc.2910470319  0.684
1991 Varani J, Astrom A, Griffiths CEM, Voorhees JJ. Induction of proliferation of growth-inhibited keratinocytes and fibroblasts in monolayer culture by sodium lauryl sulfate: Comparison with all-trans retinoic acid Journal of Investigative Dermatology. 97: 917-921. PMID 1919055 DOI: 10.1111/1523-1747.Ep12491682  0.37
1991 Petryniak J, Varani J, Ervin PR, Goldstein IJ. Differential expression of glycoproteins containing α-d-galactosyl groups on normal human breast epithelial cells and MCF-7 human breast carcinoma cells Cancer Letters. 60: 59-65. PMID 1913627 DOI: 10.1016/0304-3835(91)90049-N  0.35
1991 Schuger L, Skubitz AP, O'Shea KS, Chang JF, Varani J. Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development. Developmental Biology. 146: 531-41. PMID 1907584 DOI: 10.1016/0012-1606(91)90254-Z  0.653
1991 Varani J, Gendimenico GJ, Shah B, Gibbs D, Capetola RJ, Mezick JA, Voorhees JJ. A direct comparison of pharmacologic effects of retinoids on skin cells in vitro and in vivo. Skin Pharmacology and Physiology. 4: 254-261. PMID 1724165 DOI: 10.1159/000210959  0.391
1991 Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, Ward PA. Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats Journal of Clinical Investigation. 88: 1396-1406. PMID 1717513 DOI: 10.1172/Jci115446  0.335
1990 Schuger L, O'Shea S, Rheinheimer J, Varani J. Laminin in lung development: effects of anti-laminin antibody in murine lung morphogenesis. Developmental Biology. 137: 26-32. PMID 2403947 DOI: 10.1016/0012-1606(90)90004-3  0.655
1990 Varani J, Mitra RS, Gibbs D, Phan SH, Dixit VM, Mitra R, Wang T, Siebert KJ, Nickoloff BJ, Voorhees JJ. All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts Journal of Investigative Dermatology. 94: 717-723. PMID 2324527 DOI: 10.1111/1523-1747.Ep12876294  0.405
1990 Varani J, Chakrabarty S. Modulation of fibronectin synthesis and fibronectin binding during transformation and differentiation of mouse AKR fibroblasts. Journal of Cellular Physiology. 143: 445-54. PMID 2141611 DOI: 10.1002/Jcp.1041430307  0.375
1990 Schuger L, Dixit VM, Carey TE, Varani J. Modulation of squamous carcinoma cell growth, morphology, adhesiveness and extracellular matrix production by interferon-gamma and tumor necrosis factor-alpha. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 58: 279-86. PMID 2127530 DOI: 10.1159/000163597  0.677
1990 Markey BA, Phan SH, Varani J, Ryan US, Ward PA. Inhibition of cytotoxicity by intracellular superoxide dismutase supplementation. Free Radical Biology and Medicine. 9: 307-314. PMID 2126522 DOI: 10.1016/0891-5849(90)90005-4  0.337
1990 Yamamoto T, Varani J, Soong HK, Lighter PR. Effects of 5-fluorouracil and Mitomycin C on Cultured Rabbit Subconjunctival Fibroblasts Ophthalmology. 97: 1204-1210. PMID 2122349 DOI: 10.1016/S0161-6420(90)32456-9  0.325
1990 Riser BL, Varani J, Nickoloff BJ, Mitra RS, Dixit VM. Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis. Dermatologica. 180: 60-5. PMID 2107104 DOI: 10.1159/000247991  0.307
1989 Varani J, Fligiel SE, Inman DR, Helmreich DL, Bendelow MJ, Hillegas W. Substrate-dependent differences in production of extracellular matrix molecules by squamous carcinoma cells and diploid fibroblasts. Biotechnology and Bioengineering. 33: 1235-41. PMID 18587855 DOI: 10.1002/Bit.260331003  0.406
1989 Ginsburg I, Gibbs DF, Varani J. Interaction of mammalian cells with polymorphonuclear leukocytes: relative sensitivity to monolayer disruption and killing. Inflammation. 13: 529-42. PMID 2807519 DOI: 10.1007/Bf00916759  0.406
1989 Soong HK, Hassan T, Varani J, Huang SCM, Brennan M. Fibronectin does not enhance epidermal growth factor-mediated acceleration of corneal epithelial wound closure. Archives of Ophthalmology. 107: 1052-1054. PMID 2787627 DOI: 10.1001/Archopht.1989.01070020114042  0.342
1989 Varani J, Riser BL, Hughes LA, Carey TE, Fligiel SE, Dixit VM. Characterization of thrombospondin synthesis, secretion and cell surface expression by human tumor cells. Clinical & Experimental Metastasis. 7: 265-76. PMID 2647330 DOI: 10.1007/Bf01753679  0.417
1989 Ginsburg I, Gibbs DF, Schuger L, Johnson KJ, Ryan US, Ward PA, Varani J. Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide. Free Radical Biology & Medicine. 7: 369-76. PMID 2558061 DOI: 10.1016/0891-5849(89)90123-8  0.654
1989 Chakrabarty S, Jan Y, Levine A, McClenic B, Varani J. Fibronectin/laminin and their receptors in aberrant growth control in FR3T3 cells transformed by Ha-ras oncogene and epidermal growth factor gene. International Journal of Cancer. Journal International Du Cancer. 44: 325-31. PMID 2527209 DOI: 10.1002/Ijc.2910440223  0.337
1989 Laybourn KA, Hiserodt JC, Varani J. Laminin receptor expression on murine tumor cells: correlation with sensitivity to natural cell-mediated cytotoxicity. International Journal of Cancer. 43: 737-742. PMID 2522914 DOI: 10.1002/Ijc.2910430433  0.338
1989 Varani J, Nickoloff BJ, Dixit VM, Mitra RS, Voorhees JJ. All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion. The Journal of Investigative Dermatology. 93: 449-54. PMID 2476509 DOI: 10.1111/1523-1747.Ep12284020  0.412
1989 Shaycvilz JR, Varani J, Knight PR, Ward PA. Halothane And Isoflurane Enhance Peroxide-Induced Endothelial Cell Injury Anesthesiology. 71. DOI: 10.1097/00000542-198909001-00213  0.306
1989 Shayevitz JR, Varani J, Knight PR, Ward PA. Halothane Increases Neutrophil-Induced Endothelial Cell Cytotoxicity Anesthesiology. 71. DOI: 10.1097/00000542-198909001-00212  0.34
1989 McClenic BK, Mitra RS, Riser BL, Nickoloff BJ, Dixit VM, Varani J. Production and utilization of extracellular matrix components by human melanocytes Experimental Cell Research. 180: 314-325. DOI: 10.1016/0014-4827(89)90060-8  0.396
1988 Grimstad IA, Thorsrud AK, Varani J, Ward PA, Jellum E. Marker polypeptide differences between spontaneous strongly and weakly metastatic cancer cells identified by 2-dimensional gel electrophoresis. International Journal of Cancer. 41: 568-572. PMID 3356490 DOI: 10.1002/Ijc.2910410416  0.333
1988 Riser BL, Varani J, O'Rourke K, Dixit VM. Thrombospondin binding by human squamous carcinoma and melanoma cells: relationship to biological activity. Experimental Cell Research. 174: 319-29. PMID 3338492 DOI: 10.1016/0014-4827(88)90303-5  0.37
1988 Varani J, Bendelow MJ, Hillegas WJ. The effect of substrate on the production of infectious virus by cells in culture Journal of Biological Standardization. 16: 333-338. PMID 2848844 DOI: 10.1016/0092-1157(88)90021-2  0.327
1988 Varani J, Nickoloff BJ, Riser BL, Mitra RS, O'Rourke K, Dixit VM. Thrombospondin-induced adhesion of human keratinocytes. The Journal of Clinical Investigation. 81: 1537-44. PMID 2452837 DOI: 10.1172/Jci113486  0.4
1987 Varani J, Carey TE, Fligiel SE, McKeever PE, Dixit V. Tumor type-specific differences in cell-substrate adhesion among human tumor cell lines. International Journal of Cancer. Journal International Du Cancer. 39: 397-403. PMID 3818128 DOI: 10.1002/Ijc.2910390321  0.378
1987 Varani J, McKeever PE, Fligiel SE, Sitrin RG. Plasminogen activator production by human tumor cells: effect on tumor cell-extracellular matrix interactions. International Journal of Cancer. Journal International Du Cancer. 40: 772-7. PMID 3692623 DOI: 10.1002/Ijc.2910400611  0.398
1987 Chakrabarty S, Brattain MG, Ochs RL, Varani J. Modulation of fibronectin, laminin, and cellular adhesion in the transformation and differentiation of murine AKR fibroblasts. Journal of Cellular Physiology. 133: 415-25. PMID 3320063 DOI: 10.1002/Jcp.1041330302  0.379
1987 McKeever PE, Hood TW, Varani J, Taren JA, Beierwaltes WH, Wahl R, Liebert M, Nguyen PK. Products of cells cultured from gliomas. V. Cytology and morphometry of two cell types cultured from glioma. Journal of the National Cancer Institute. 78: 75-84. PMID 3025505 DOI: 10.1093/Jnci/78.1.75  0.373
1986 Varani J, Dixit VM, Fligiel SE, McKeever PE, Carey TE. Thrombospondin-induced attachment and spreading of human squamous carcinoma cells. Experimental Cell Research. 167: 376-90. PMID 3770094 DOI: 10.1016/0014-4827(86)90178-3  0.418
1986 Varani J, Bendelow MJ, Chun JH, Hillegas WA. Cell growth on microcarriers: comparison of proliferation on and recovery from various substrates. Journal of Biological Standardization. 14: 331-336. PMID 3558416 DOI: 10.1016/0092-1157(86)90020-X  0.372
1986 Fligiel SEG, Laybourn KA, Peters BP, Ruddon RW, Hiserodt JC, Varani J. Laminin production by murine melanoma cells: possible involvement in cell motility Clinical & Experimental Metastasis. 4: 259-272. PMID 3539434 DOI: 10.1007/Bf00133591  0.362
1986 McKeever PE, Fligiel SE, Varani J, Hudson JL, Smith D, Castle RL, McCoy JP. Products of cells cultured from gliomas. IV. Extracellular matrix proteins of gliomas. International Journal of Cancer. Journal International Du Cancer. 37: 867-74. PMID 3519474 DOI: 10.1002/Ijc.2910370612  0.396
1986 He X, Fligiel SEG, Varani J. Modulation of tumor cell motility by prostaglandins and inhibitors of prostaglandin synthesis. Pathobiology. 54: 128-137. PMID 3462058 DOI: 10.1159/000163450  0.303
1986 Varani J, Hasday JD, Sitrin RG, Brubaker PG, hillegas WA. Proteolytic enzymes and arachidonic acid metabolites produced by MRC-5 cells on various microcarrier substrates In Vitro Cellular & Developmental Biology – Plant. 22: 575-582. PMID 3095307 DOI: 10.1007/Bf02623516  0.38
1986 Batchev AC, Riser BL, Hellner EG, Fligiel SEG, Varani J. Phorbol ester binding and phorol ester-induced arachidonic acid metabolism in a highly responsive murine fibrosarcoma cell line and in a less-responsive variant Clinical & Experimental Metastasis. 4: 51-61. PMID 3084151 DOI: 10.1007/Bf00053473  0.326
1985 Varani J, Grimstad IA, Knibbs RN, Hovig T, McCoy JP. Attachment, spreading and growth in vitro of highly malignant and low malignant murine fibrosarcoma cells Clinical & Experimental Metastasis. 3: 45-59. PMID 4042456 DOI: 10.1007/Bf01758953  0.385
1985 Varani J, Fligeil SEG, Perone P. Directional motility in strongly malignant murine tumor cells International Journal of Cancer. 35: 559-564. PMID 3988372 DOI: 10.1002/Ijc.2910350422  0.404
1985 Varani J, Dame M, Rediske J, Beals TF, Hillegas W. Substrate-dependent differences in growth and biological properties of fibroblasts and epithelial cells grown in microcarrier culture. Journal of Biological Standardization. 13: 67-76. PMID 2985616 DOI: 10.1016/S0092-1157(85)80035-4  0.413
1985 Varani J, Perone P. Response of Walker 256 Carcinosarcoma Cells to 12-O-Tetradecanoylphorbol 13-Acetate: Possible Regulation by Endogenous Cyclooxygenase Metabolites Journal of the National Cancer Institute. 74: 165-172. DOI: 10.1093/Jnci/74.1.165  0.367
1985 Fligiel SEG, Perone P, Varani J. Arachidonic acid metabolism in murine fibrosarcoma cells with differing in vivo and in vitro characteristics. International Journal of Cancer. 36: 383-388. DOI: 10.1002/Ijc.1985.36.3.383  0.393
1984 Grimstad IA, Varani J, McCoy JP. Contribution of α-d-galactopyranosyl end groups to attachment of highly and low metastatic murine fibrosarcoma cells to various substrates☆ Experimental Cell Research. 155: 345-358. PMID 6094221 DOI: 10.1016/0014-4827(84)90195-2  0.371
1983 Varani J, Lovett EJ, Wicha M, Malinoff H, McCoy JP. Cell Surface α-D-Galactopyranosyl End Groups: Use as Markers in the Isolation of Murine Tumor Cell Lines With Different Cancer-Causing Potentials Journal of the National Cancer Institute. 71: 1281-1287. DOI: 10.1093/Jnci/71.6.1281  0.316
1982 Varani J. Themotaxis of metastatic tumor cells Cancer and Metastasis Reviews. 1: 17-28. PMID 7185418 DOI: 10.1007/Bf00049478  0.37
1982 Varani J, Lovett EJ. Phenotypic Stability of Murine Tumor Cells In Vitro and In Vivo Journal of the National Cancer Institute. 68: 957-962. DOI: 10.1093/Jnci/68.6.957  0.328
1981 Wass JA, Varani J, Piontek GE, Ward PA, Orr FW. Responses Of Normal And Malignant Cells To Collagen, Collagen-Derived Peptides And The C5-Related Tumor Cell Chemotactic Peptide Mechanisms of Development. 10: 329-332. PMID 7317948 DOI: 10.1016/0045-6039(81)90024-5  0.331
1981 Varani J, Wass JA, Piontek GE, Ward PA. Chemotactic factor-induced adherence of tumor cells Cell Biology International Reports. 5: 525-530. PMID 7237582 DOI: 10.1016/0309-1651(81)90180-6  0.319
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