Niklas Mejhert - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Klingelhuber F, Frendo-Cumbo S, Omar-Hmeadi M, Massier L, Kakimoto P, Taylor AJ, Couchet M, Ribicic S, Wabitsch M, Messias AC, Iuso A, Müller TD, Rydén M, Mejhert N, Krahmer N. A spatiotemporal proteomic map of human adipogenesis. Nature Metabolism. PMID 38565923 DOI: 10.1038/s42255-024-01025-8  0.712
2024 Ludzki AC, Hansen M, Zareifi D, Jalkanen J, Huang Z, Omar-Hmeadi M, Renzi G, Klingelhuber F, Boland S, Ambaw YA, Wang N, Damdimopoulos A, Liu J, Jernberg T, Petrus P, ... ... Mejhert N, et al. Transcriptional determinants of lipid mobilization in human adipocytes. Science Advances. 10: eadi2689. PMID 38170777 DOI: 10.1126/sciadv.adi2689  0.725
2023 Couchet M, Gao H, Klingelhuber F, Jalkanen J, De Castro Barbosa T, Omar-Hmeadi M, Massier L, Krahmer N, Mejhert N, Rydén M. Adipogenic characterization of immortalized CD55 progenitor cells from human white adipose tissue. Adipocyte. 2283213. PMID 37982546 DOI: 10.1080/21623945.2023.2283213  0.683
2022 Mejhert N, Rydén M. Insights from Studies of White Adipose Tissue Using Single-Cell Approaches. Handbook of Experimental Pharmacology. PMID 35318510 DOI: 10.1007/164_2021_578  0.307
2022 Maqdasy S, Lecoutre S, Renzi G, Frendo-Cumbo S, Rizo-Roca D, Moritz T, Juvany M, Hodek O, Gao H, Couchet M, Witting M, Kerr A, Bergo MO, Choudhury RP, Aouadi M, ... ... Mejhert N, et al. Impaired phosphocreatine metabolism in white adipocytes promotes inflammation. Nature Metabolism. 4: 190-202. PMID 35165448 DOI: 10.1038/s42255-022-00525-9  0.338
2022 Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer N, Song J, Kuruvilla L, Chitraju C, Boland S, Jang DK, von Grotthuss M, Costanzo MC, Rydén M, Olzmann JA, Flannick J, Burtt NP, et al. The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology. Developmental Cell. 57: 387-397.e4. PMID 35134345 DOI: 10.1016/j.devcel.2022.01.003  0.738
2021 Shen JX, Couchet M, Dufau J, de Castro Barbosa T, Ulbrich MH, Helmstädter M, Kemas AM, Zandi Shafagh R, Marques MA, Hansen JB, Mejhert N, Langin D, Rydén M, Lauschke VM. 3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100106. PMID 34165908 DOI: 10.1002/advs.202100106  0.304
2021 Mileti E, Kwok KH, Andersson DP, Mathelier A, Raman A, Bäckdahl J, Jalkanen J, Massier L, Thorell A, Gao H, Arner P, Mejhert N, Daub CO, Rydén M. Human white adipose tissue displays selective insulin resistance in the obese state. Diabetes. PMID 33863803 DOI: 10.2337/db21-0001  0.521
2021 Dufau J, Shen JX, Couchet M, De Castro Barbosa T, Mejhert N, Massier L, Griseti E, Mouisel E, Amri EZ, Lauschke VM, Rydén M, Langin D. In vitro and ex vivo models of adipocytes. American Journal of Physiology. Cell Physiology. 320: C822-C841. PMID 33439778 DOI: 10.1152/ajpcell.00519.2020  0.34
2020 Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai ZW, Farese RV, Walther TC. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Reports. 33: 108378. PMID 33176155 DOI: 10.1016/j.celrep.2020.108378  0.509
2020 Lecoutre S, Maqdasy S, Petrus P, Ludzki A, Couchet M, Mejhert N, Rydén M. Glutamine metabolism in adipocytes: a epigenetic modulator of inflammation. Adipocyte. 9: 620-625. PMID 33043853 DOI: 10.1080/21623945.2020.1831825  0.338
2020 Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. The Journal of Cell Biology. 219. PMID 32915949 DOI: 10.1083/Jcb.202006111  0.575
2020 Gao H, Arner P, Beauchef G, Guéré C, Vie K, Dahlman I, Mejhert N, Rydén M. Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation. Cell Metabolism. PMID 32589948 DOI: 10.1016/J.Cmet.2020.06.007  0.482
2020 Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant mice, a model of motor neuron degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 32345721 DOI: 10.1073/Pnas.1913956117  0.514
2020 Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Molecular Cell. PMID 32023484 DOI: 10.1016/J.Molcel.2020.01.014  0.618
2019 Gluchowski NL, Gabriel KR, Chitraju C, Bronson RT, Mejhert N, Boland S, Wang K, Lai ZW, Farese RV, Walther TC. Hepatocyte Deletion of Triglyceride-Synthesis Enzyme DGAT2 Reduces Steatosis without Increasing Inflammation or Fibrosis. Hepatology (Baltimore, Md.). PMID 31081165 DOI: 10.1002/Hep.30765  0.558
2018 Petrus P, Mejhert N, Corrales P, Lecoutre S, Li Q, Maldonado E, Kulyté A, Lopez Y, Campbell M, Acosta JR, Laurencikiene J, Douagi I, Gao H, Martínez-Álvarez C, Hedén P, et al. Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue. Cell Reports. 25: 551-560.e5. PMID 30332637 DOI: 10.1016/J.Celrep.2018.09.069  0.562
2017 Belarbi Y, Mejhert N, Gao H, Arner P, Rydén M, Kulyté A. MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue. Molecular and Cellular Endocrinology. PMID 29191698 DOI: 10.1016/J.Mce.2017.11.018  0.497
2017 Petrus P, Bialesova L, Checa A, Kerr A, Naz S, Bäckdahl J, Gracia A, Toft S, Dahlman-Wright K, Hedén P, Dahlman I, Wheelock CE, Arner P, Mejhert N, Gao H, et al. Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance. The Journal of Clinical Endocrinology and Metabolism. PMID 29121255 DOI: 10.1210/Jc.2017-01382  0.525
2017 Bombrun M, Gao H, Ranefall P, Mejhert N, Arner P, Wählby C. Quantitative high-content/high-throughput microscopy analysis of lipid droplets in subject-specific adipogenesis models. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 29031005 DOI: 10.1002/Cyto.A.23265  0.555
2017 Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, ... ... Mejhert N, et al. FANTOM5 CAGE profiles of human and mouse samples. Scientific Data. 4: 170112. PMID 28850106 DOI: 10.1038/Sdata.2017.112  0.503
2017 de Rie D, Abugessaisa I, Alam T, Arner E, Arner P, Ashoor H, Åström G, Babina M, Bertin N, Burroughs AM, Carlisle AJ, Daub CO, Detmar M, Deviatiiarov R, Fort A, ... ... Mejhert N, et al. An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology. PMID 28829439 DOI: 10.1038/Nbt.3947  0.465
2017 Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV. Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis. Cell Metabolism. 26: 407-418.e3. PMID 28768178 DOI: 10.1016/J.Cmet.2017.07.012  0.6
2017 Hesselbarth N, Kunath A, Kern M, Gericke M, Mejhert N, Rydén M, Stumvoll M, Blüher M, Klöting N. Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism. International Journal of Obesity. 41: 1815-1823. PMID 28736440 DOI: 10.1038/Ijo.2017.172  0.441
2017 Gao H, Volat F, Sandhow L, Galitzky J, Nguyen T, Esteve D, Åström G, Mejhert N, Ledoux S, Thalamas C, Arner P, Guillemot JC, Qian H, Rydén M, Bouloumié A. CD36 is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential. Stem Cells (Dayton, Ohio). PMID 28470788 DOI: 10.1002/Stem.2635  0.495
2017 Gluchowski NL, Chitraju C, Picoraro JA, Mejhert N, Pinto S, Xin W, Kamin DS, Winter HS, Chung WK, Walther TC, Farese RV. Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea. Journal of Lipid Research. PMID 28373485 DOI: 10.1194/Jlr.P075119  0.52
2016 Ehrlund A, Mejhert N, Björk C, Andersson R, Kulyté A, Åström G, Itoh M, Kawaji H, Lassmann T, Daub CO, Carninci P, Forrest AR, Hayashizaki Y, Sandelin A, Ingelsson E, et al. Transcriptional Dynamics During Human Adipogenesis and its Link to Adipose Morphology and Distribution. Diabetes. PMID 27803022 DOI: 10.2337/Db16-0631  0.578
2016 Eriksson Hogling D, Petrus P, Gao H, Bäckdahl J, Dahlman I, Laurencikiene J, Acosta J, Ehrlund A, Näslund E, Kulyte A, Mejhert N, Andersson DP, Arner P, Rydén M. Adipose and circulating CCL18 levels associate with metabolic risk factors in women. The Journal of Clinical Endocrinology and Metabolism. jc20162390. PMID 27459538 DOI: 10.1210/Jc.2016-2390  0.579
2015 Rydén M, Uzunel M, Hård JL, Borgström E, Mold JE, Arner E, Mejhert N, Andersson DP, Widlund Y, Hassan M, Jones CV, Spalding KL, Svahn BM, Ahmadian A, Frisén J, et al. Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis. Cell Metabolism. PMID 26190649 DOI: 10.1016/J.Cmet.2015.06.011  0.51
2015 Belarbi Y, Mejhert N, Lorente-Cebrián S, Dahlman I, Arner P, Rydén M, Kulyté A. MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue. The Journal of Clinical Endocrinology and Metabolism. 100: E1084-8. PMID 26020766 DOI: 10.1210/Jc.2015-1530  0.558
2015 Petrus P, Rosqvist F, Edholm D, Mejhert N, Arner P, Dahlman I, Rydén M, Sundbom M, Risérus U. Saturated fatty acids in human visceral adipose tissue are associated with increased 11- β-hydroxysteroid-dehydrogenase type 1 expression. Lipids in Health and Disease. 14: 42. PMID 25934644 DOI: 10.1186/S12944-015-0042-1  0.566
2015 Minchin JE, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J, Rawls JF. Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. Proceedings of the National Academy of Sciences of the United States of America. 112: 4363-8. PMID 25831505 DOI: 10.1073/Pnas.1416412112  0.573
2015 Petrus P, Mejhert N, Gao H, Bäckdahl J, Arner E, Arner P, Rydén M. Low early B-cell factor 1 (EBF1) activity in human subcutaneous adipose tissue is linked to a pernicious metabolic profile. Diabetes & Metabolism. PMID 25791133 DOI: 10.1016/J.Diabet.2015.02.004  0.574
2015 Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B, Drabløs F, Lennartsson A, Rönnerblad M, Hrydziuszko O, Vitezic M, Freeman TC, Alhendi AM, Arner P, Axton R, Baillie JK, ... ... Mejhert N, et al. Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (New York, N.Y.). 347: 1010-4. PMID 25678556 DOI: 10.1126/Science.1259418  0.497
2014 Gao H, Mejhert N, Fretz JA, Arner E, Lorente-Cebrián S, Ehrlund A, Dahlman-Wright K, Gong X, Strömblad S, Douagi I, Laurencikiene J, Dahlman I, Daub CO, Rydén M, Horowitz MC, et al. Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue. Cell Metabolism. 19: 981-92. PMID 24856929 DOI: 10.1016/J.Cmet.2014.03.032  0.624
2014 Andersson DP, Eriksson Hogling D, Thorell A, Toft E, Qvisth V, Näslund E, Thörne A, Wirén M, Löfgren P, Hoffstedt J, Dahlman I, Mejhert N, Rydén M, Arner E, Arner P. Changes in subcutaneous fat cell volume and insulin sensitivity after weight loss. Diabetes Care. 37: 1831-6. PMID 24760260 DOI: 10.2337/Dc13-2395  0.545
2014 Arner E, Forrest AR, Ehrlund A, Mejhert N, Itoh M, Kawaji H, Lassmann T, Laurencikiene J, Rydén M, Arner P. Ceruloplasmin is a novel adipokine which is overexpressed in adipose tissue of obese subjects and in obesity-associated cancer cells. Plos One. 9: e80274. PMID 24676332 DOI: 10.1371/Journal.Pone.0080274  0.561
2014 Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, ... ... Mejhert N, et al. A promoter-level mammalian expression atlas. Nature. 507: 462-70. PMID 24670764 DOI: 10.1038/Nature13182  0.536
2014 Lorente-Cebrián S, Mejhert N, Kulyté A, Laurencikiene J, Åström G, Hedén P, Rydén M, Arner P. MicroRNAs regulate human adipocyte lipolysis: effects of miR-145 are linked to TNF-α. Plos One. 9: e86800. PMID 24475180 DOI: 10.1371/Journal.Pone.0086800  0.494
2014 Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, ... ... Mejhert N, et al. Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 156: 343-58. PMID 24439387 DOI: 10.1016/J.Cell.2013.10.058  0.507
2014 Kulyté A, Belarbi Y, Lorente-Cebrián S, Bambace C, Arner E, Daub CO, Hedén P, Rydén M, Mejhert N, Arner P. Additive effects of microRNAs and transcription factors on CCL2 production in human white adipose tissue. Diabetes. 63: 1248-58. PMID 24379347 DOI: 10.2337/Db13-0702  0.53
2014 Kulyté A, Lorente-Cebrián S, Gao H, Mejhert N, Agustsson T, Arner P, Rydén M, Dahlman I. MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia. American Journal of Physiology. Endocrinology and Metabolism. 306: E267-74. PMID 24326420 DOI: 10.1152/Ajpendo.00249.2013  0.52
2013 Pettersson AML, Stenson BM, Lorente-Cebrián S, Andersson DP, Mejhert N, Krätzel J, Åström G, Dahlman I, Chibalin AV, Arner P, Laurencikiene J. LXR is a negative regulator of glucose uptake in human adipocytes Diabetologia. 56: 2044-2054. PMID 23765184 DOI: 10.1007/S00125-013-2954-5  0.555
2013 Mejhert N, Wilfling F, Esteve D, Galitzky J, Pellegrinelli V, Kolditz CI, Viguerie N, Tordjman J, Näslund E, Trayhurn P, Lacasa D, Dahlman I, Stich V, Lång P, Langin D, et al. Semaphorin 3C is a novel adipokine linked to extracellular matrix composition. Diabetologia. 56: 1792-801. PMID 23666167 DOI: 10.1007/S00125-013-2931-Z  0.719
2013 Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B, Waget A, et al. Partial Inhibition of Adipose Tissue Lipolysis Improves Glucose Metabolism and Insulin Sensitivity Without Alteration of Fat Mass Plos Biology. 11. PMID 23431266 DOI: 10.1371/Journal.Pbio.1001485  0.59
2013 Ehrlund A, Mejhert N, Lorente-Cebrián S, Aström G, Dahlman I, Laurencikiene J, Rydén M. Characterization of the Wnt inhibitors secreted frizzled-related proteins (SFRPs) in human adipose tissue. The Journal of Clinical Endocrinology and Metabolism. 98: E503-8. PMID 23393180 DOI: 10.1210/Jc.2012-3416  0.413
2012 Arner E, Mejhert N, Kulyté A, Balwierz PJ, Pachkov M, Cormont M, Lorente-Cebrián S, Ehrlund A, Laurencikiene J, Hedén P, Dahlman-Wright K, Tanti JF, Hayashizaki Y, Rydén M, Dahlman I, et al. Adipose tissue microRNAs as regulators of CCL2 production in human obesity. Diabetes. 61: 1986-93. PMID 22688341 DOI: 10.2337/Db11-1508  0.527
2012 Anveden Ã…, Sjöholm K, Jacobson P, Palsdottir V, Walley AJ, Froguel P, Al-Daghri N, McTernan PG, Mejhert N, Arner P, Sjöström L, Carlsson LM, Svensson PA. ITIH-5 expression in human adipose tissue is increased in obesity. Obesity (Silver Spring, Md.). 20: 708-14. PMID 21852814 DOI: 10.1038/Oby.2011.268  0.596
2012 Lorente-Cebrián S, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Aström G, Sjölin E, WÃ¥hlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M. Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. European Journal of Nutrition. 51: 335-42. PMID 21701898 DOI: 10.1007/S00394-011-0218-Z  0.559
2011 Kulyté A, Rydén M, Mejhert N, Dungner E, Sjölin E, Arner P, Dahlman I. MTCH2 in human white adipose tissue and obesity. The Journal of Clinical Endocrinology and Metabolism. 96: E1661-5. PMID 21795451 DOI: 10.1210/Jc.2010-3050  0.535
2011 Jiao H, Arner P, Dickson SL, Vidal H, Mejhert N, Henegar C, Taube M, Hansson C, Hinney A, Galan P, Simon C, Silveira A, Benrick A, Jansson JO, Bouloumié A, et al. Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity. The Journal of Clinical Endocrinology and Metabolism. 96: E962-6. PMID 21430024 DOI: 10.1210/Jc.2010-2639  0.528
2011 Pettersson AT, Mejhert N, Jernås M, Carlsson LM, Dahlman I, Laurencikiene J, Arner P, Rydén M. Twist1 in human white adipose tissue and obesity. The Journal of Clinical Endocrinology and Metabolism. 96: 133-41. PMID 20943789 DOI: 10.1210/Jc.2010-0929  0.595
2010 Dahlman I, Mejhert N, Linder K, Agustsson T, Mutch DM, Kulyte A, Isaksson B, Permert J, Petrovic N, Nedergaard J, Sjölin E, Brodin D, Clement K, Dahlman-Wright K, Rydén M, et al. Adipose tissue pathways involved in weight loss of cancer cachexia. British Journal of Cancer. 102: 1541-8. PMID 20407445 DOI: 10.1038/Sj.Bjc.6605665  0.583
2010 Mejhert N, Galitzky J, Pettersson AT, Bambace C, Blomqvist L, Bouloumié A, Frayn KN, Dahlman I, Arner P, Rydén M. Mapping of the fibroblast growth factors in human white adipose tissue. The Journal of Clinical Endocrinology and Metabolism. 95: 2451-7. PMID 20228166 DOI: 10.1210/Jc.2009-2049  0.557
2010 Mejhert N, Laurencikiene J, Pettersson AT, Kaaman M, Stenson BM, Rydén M, Dahlman I. Role of Receptor-Interacting Protein 140 in human fat cells. Bmc Endocrine Disorders. 10: 1. PMID 20205832 DOI: 10.1186/1472-6823-10-1  0.47
2010 Pettersson AT, Laurencikiene J, Mejhert N, Näslund E, Bouloumié A, Dahlman I, Arner P, Rydén M. A possible inflammatory role of twist1 in human white adipocytes. Diabetes. 59: 564-71. PMID 20007935 DOI: 10.2337/Db09-0997  0.564
2009 Flanagan JN, Linder K, Mejhert N, Dungner E, Wahlen K, Decaunes P, Rydén M, Björklund P, Arver S, Bhasin S, Bouloumie A, Arner P, Dahlman I. Role of follistatin in promoting adipogenesis in women. The Journal of Clinical Endocrinology and Metabolism. 94: 3003-9. PMID 19470636 DOI: 10.1210/Jc.2008-2005  0.572
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