Simon Mitchell - Publications

Affiliations: 
Brighton and Sussex Medical School, Falmer, England, United Kingdom 
Area:
Systems Biology, Lymphoma, DLBCL

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jayawant E, Pack A, Clark H, Kennedy E, Ghodke A, Jones J, Pepper C, Pepper A, Mitchell S. NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma. Frontiers in Oncology. 13: 1181660. PMID 37333821 DOI: 10.3389/fonc.2023.1181660  0.326
2023 O'Donnell A, Pepper C, Mitchell S, Pepper A. NF-kB and the CLL microenvironment. Frontiers in Oncology. 13: 1169397. PMID 37064123 DOI: 10.3389/fonc.2023.1169397  0.377
2023 Mitchell S, Tsui R, Tan ZC, Pack A, Hoffmann A. The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts. Science Signaling. 16: eabo2838. PMID 36917644 DOI: 10.1126/scisignal.abo2838  0.651
2022 Burley TA, Hesketh A, Bucca G, Kennedy E, Ladikou EE, Towler BP, Mitchell S, Smith CP, Fegan C, Johnston R, Pepper A, Pepper C. Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia. Cancers. 14. PMID 35406371 DOI: 10.3390/cancers14071600  0.304
2022 Burley TA, Kennedy E, Broad G, Boyd M, Li D, Woo T, West C, Ladikou EE, Ashworth I, Fegan C, Johnston R, Mitchell S, Mackay SP, Pepper AGS, Pepper C. Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma. Cancers. 14. PMID 35326640 DOI: 10.3390/cancers14061489  0.343
2020 Oliver Metzig M, Tang Y, Mitchell S, Taylor B, Foreman R, Wollman R, Hoffmann A. An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions. Molecular Systems Biology. 16: e9677. PMID 33314666 DOI: 10.15252/msb.20209677  0.609
2020 Ngo KA, Kishimoto K, Davis-Turak J, Pimplaskar A, Cheng Z, Spreafico R, Chen EY, Tam A, Ghosh G, Mitchell S, Hoffmann A. Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics. Cell Reports. 30: 2758-2775.e6. PMID 32101750 DOI: 10.1016/J.Celrep.2020.01.108  0.478
2019 Mitchell S, Mercado EL, Adelaja A, Ho JQ, Cheng QJ, Ghosh G, Hoffmann A. An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms. Frontiers in Immunology. 10: 1425. PMID 31293585 DOI: 10.3389/Fimmu.2019.01425  0.492
2019 Mitchell S, Hoffmann A. Substrate complex competition is a regulatory motif that allows NFκB RelA to license but not amplify NFκB RelB. Proceedings of the National Academy of Sciences of the United States of America. PMID 31048505 DOI: 10.1073/Pnas.1816000116  0.468
2019 Roy K, Mitchell S, Liu Y, Ohta S, Lin YS, Metzig MO, Nutt SL, Hoffmann A. A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation. Immunity. PMID 30850343 DOI: 10.1016/J.Immuni.2019.02.004  0.485
2018 Yeom KH, Mitchell S, Linares AJ, Zheng S, Lin CH, Wang XJ, Hoffmann A, Black DL. Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse. Proceedings of the National Academy of Sciences of the United States of America. PMID 30401736 DOI: 10.1073/Pnas.1809609115  0.348
2018 Mitchell S, Hoffmann A. Identifying Noise Sources governing cell-to-cell variability. Current Opinion in Systems Biology. 8: 39-45. PMID 29623300 DOI: 10.1016/J.Coisb.2017.11.013  0.438
2018 Mitchell S, Roy K, Zangle TA, Hoffmann A. Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29514960 DOI: 10.1073/Pnas.1715639115  0.46
2018 Roy K, Shokhirev MN, Mitchell S, Hoffmann A. Deriving Quantitative Cell Biological Information from Dye-Dilution Lymphocyte Proliferation Experiments. Methods in Molecular Biology (Clifton, N.J.). 1707: 81-94. PMID 29388101 DOI: 10.1007/978-1-4939-7474-0_6  0.609
2016 Mitchell S, Vargas J, Hoffmann A. Signaling via the NFκB system. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 26990581 DOI: 10.1002/Wsbm.1331  0.552
2015 Spreafico R, Mitchell S, Hoffmann A. Training the 21st Century Immunologist. Trends in Immunology. 36: 283-5. PMID 25911462 DOI: 10.1016/J.It.2015.04.001  0.389
2015 Mitchell S, Tsui R, Hoffmann A. Studying NF-κB signaling with mathematical models. Methods in Molecular Biology (Clifton, N.J.). 1280: 647-61. PMID 25736777 DOI: 10.1007/978-1-4939-2422-6_38  0.637
2013 Mitchell S, Mendes P. A computational model of liver iron metabolism. Plos Computational Biology. 9: e1003299. PMID 24244122 DOI: 10.1371/Journal.Pcbi.1003299  0.436
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