Manoj M. Lalu, M.D., Ph.D. - Publications

Affiliations: 
1999-2004 PhD - Pharmacology University of Alberta, Edmonton, Alberta, Canada 
 2003-2006 Post-doctoral fellow - Obstetrics and Gynecology University of Alberta, Edmonton, Alberta, Canada 
 2003-2008 MD University of Alberta, Edmonton, Alberta, Canada 
 2008-2014 FRCPC - Anesthesiology University of Ottawa, Ottawa, ON, Canada 
 2014-2016 Post-doctoral fellow - Regenerative Medicine University of Ottawa, Ottawa, ON, Canada 
 2016- Professor - Anesthesiology and Pain Medicine Ottawa Hospital Research Institute/University of Ottawa 
Area:
Mesenchymal stromal cells, extracellular vesicles
Website:
https://www.ohri.ca/profile/mlalu

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Verret M, Le JBP, Lalu MM, McIsaac DI, Nicholls S, Turgeon AF, Hutton B, Zivkovic F, Graham M, Le M, Geist A, Berube M, Gilron I, Poulin P, Daudt H, et al. Effectiveness of dexmedetomidine during surgery under general anaesthesia on patient-centred outcomes: a systematic review and Bayesian meta-analysis protocol. Bmj Open. 14: e080012. PMID 38307526 DOI: 10.1136/bmjopen-2023-080012  0.775
2024 Nguyen F, Liao G, McIsaac DI, Lalu MM, Pysyk CL, Hamilton GM. Perioperative quality indicators specific to the practice of anesthesia in noncardiac surgery: an umbrella review. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 38182828 DOI: 10.1007/s12630-023-02671-4  0.298
2023 Lenet T, McIsaac DI, Hallet JH, Jerath A, Lalu MM, Nicholls SG, Presseau J, Tinmouth A, Verret M, Wherrett CG, Fergusson DA, Martel G. Intraoperative Blood Management Strategies for Patients Undergoing Noncardiac Surgery: The Ottawa Intraoperative Transfusion Consensus. Jama Network Open. 6: e2349559. PMID 38153742 DOI: 10.1001/jamanetworkopen.2023.49559  0.76
2023 Sobh M, Lagali PS, Ghiasi M, Montroy J, Dollin M, Hurley B, Leonard BC, Dimopoulos I, Lafreniere M, Fergusson DA, Lalu MM, Tsilfidis C. Safety and Efficacy of Adeno-Associated Viral Gene Therapy in Patients With Retinal Degeneration: A Systematic Review and Meta-Analysis. Translational Vision Science & Technology. 12: 24. PMID 37982768 DOI: 10.1167/tvst.12.11.24  0.57
2023 Jeffers MS, MacLellan A, Avey MT, Menon JM, Sunohara-Neilson J, Fergusson DA, Lalu MM. A call to implement preclinical study registration in animal ethics review. Plos Biology. 21: e3002293. PMID 37796782 DOI: 10.1371/journal.pbio.3002293  0.783
2023 Tieu A, Stewart DJ, Chwastek D, Lansdell C, Burger D, Lalu MM. Biodistribution of mesenchymal stromal cell-derived extracellular vesicles administered during acute lung injury. Stem Cell Research & Therapy. 14: 250. PMID 37705086 DOI: 10.1186/s13287-023-03472-8  0.774
2023 Fox G, Lalu MM, Sabloff T, Nicholls SG, Smith M, Stacey D, Almoli F, Fergusson DA. Recognizing patient partner contributions to health research: a systematic review of reported practices. Research Involvement and Engagement. 9: 80. PMID 37689741 DOI: 10.1186/s40900-023-00488-5  0.8
2023 Engel JS, Beckerleg W, Wijeysundera DN, Aucoin S, Leblanc J, Gagne S, Bryson GL, Lalu MM, Wyand A, McIsaac DI. Association of preoperative anaesthesia consultation prior to elective noncardiac surgery with patient and health system outcomes: a population-based study. British Journal of Anaesthesia. 131: 937-946. PMID 37666742 DOI: 10.1016/j.bja.2023.07.025  0.276
2023 Sharma N, Chwastek D, Dwivedi DJ, Schlechte J, Yu IL, McDonald B, Arora J, Cani E, Eng M, Engelberts D, Kuhar E, Medeiros SK, Bourque SL, Cepinskas G, Gill SE, ... ... Lalu MM, et al. Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions. Intensive Care Medicine Experimental. 11: 45. PMID 37460911 DOI: 10.1186/s40635-023-00533-3  0.765
2023 Cobey KD, Fehlmann CA, Christ Franco M, Ayala AP, Sikora L, Rice DB, Xu C, Ioannidis JPA, Lalu MM, Ménard A, Neitzel A, Nguyen B, Tsertsvadze N, Moher D. Epidemiological characteristics and prevalence rates of research reproducibility across disciplines: a scoping review of articles published in 2018-2019. Elife. 12. PMID 37341380 DOI: 10.7554/eLife.78518  0.405
2023 Barnes K, Hladkowicz E, Dorrance K, Bryson GL, Forster AJ, Gagné S, Huang A, Lalu MM, Lavallée LT, Saunders C, Moloo H, Nantel J, Power B, Scheede-Bergdahl C, Taljaard M, et al. Barriers and facilitators to participation in exercise prehabilitation before cancer surgery for older adults with frailty: a qualitative study. Bmc Geriatrics. 23: 356. PMID 37280523 DOI: 10.1186/s12877-023-03990-3  0.252
2023 Yu M, Montroy J, Fergusson D, Lalu MM, Kimmelman J. Matured Forecast Analyses for "Systematic and narrative review lead experts to different cancer trial predictions". Journal of Clinical Epidemiology. PMID 37211326 DOI: 10.1016/j.jclinepi.2023.05.009  0.573
2023 Viswanathan S, Blanc KL, Ciccocioppo R, Dagher G, Filiano AJ, Galipeau J, Krampera M, Krieger L, Lalu MM, Nolta J, Rodriguez Pardo VM, Shi Y, Tarte K, Weiss DJ, Martin I. An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes. Cytotherapy. PMID 37149800 DOI: 10.1016/j.jcyt.2023.04.005  0.355
2023 Verret M, Fergusson DA, Nicholls SG, Graham M, Zivkovic F, Lê M, Geist A, Lam NH, Graham ID, Turgeon AF, McIsaac DI, Lalu MM. Engaging patients in anesthesiology research: a rewarding frontier. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 36959493 DOI: 10.1007/s12630-023-02432-3  0.769
2023 Zhang M, Fergusson DA, Sharma R, Khoo C, Mendelson AA, McDonald B, Macala KF, Sharma N, Gill SE, Fiest KM, Lehmann C, Shorr R, Jahandideh F, Bourque SL, Liaw PC, ... ... Lalu MM, et al. Sex-based analysis of treatment responses in animal models of sepsis: a preclinical systematic review protocol. Systematic Reviews. 12: 50. PMID 36945012 DOI: 10.1186/s13643-023-02189-2  0.608
2023 Hunniford VT, Grudniewicz A, Fergusson DA, Montroy J, Grigor E, Lansdell C, Lalu MM. A systematic assessment of preclinical multilaboratory studies and a comparison to single laboratory studies. Elife. 12. PMID 36892457 DOI: 10.7554/eLife.76300  0.811
2023 Verret M, Lam NH, Fergusson DA, G Nicholls S, Turgeon AF, McIsaac DI, Gilron I, Hamtiaux M, Srichandramohan S, Al-Mazidi A, A Fergusson N, Hutton B, Zivkovic F, Graham M, Geist A, ... ... Lalu MM, et al. Intraoperative pharmacologic opioid minimisation strategies and patient-centred outcomes after surgery: a scoping review protocol. Bmj Open. 13: e070748. PMID 36858477 DOI: 10.1136/bmjopen-2022-070748  0.771
2023 Bastin DJ, Montroy J, Kennedy MA, Martel AB, Shorr R, Ghiasi M, Boucher DM, Wong B, Gresham L, Diallo JS, Fergusson DA, Lalu MM, Kekre N, Auer RC. Safety and efficacy of autologous cell vaccines in solid tumors: a systematic review and meta-analysis of randomized control trials. Scientific Reports. 13: 3347. PMID 36849805 DOI: 10.1038/s41598-023-29630-9  0.588
2023 Engel JS, Tran J, Khalil N, Hladkowicz E, Lalu MM, Huang A, Wong CL, Hutton B, Dhesi JK, McIsaac DI. A systematic review of perioperative clinical practice guidelines for care of older adults living with frailty. British Journal of Anaesthesia. PMID 36707368 DOI: 10.1016/j.bja.2022.12.010  0.326
2023 Lalu MM, Kekre N, Montroy J, Ghiasi M, Hay K, McComb S, Weeratna R, Atkins H, Hutton B, Yahya A, Masurekar A, Sobh M, Fergusson DA. Identifying effect modifiers of CAR-T cell therapeutic efficacy: a systematic review and individual patient data meta-analysis protocol. Systematic Reviews. 12: 9. PMID 36653879 DOI: 10.1186/s13643-022-02158-1  0.6
2023 Lalu MM, Presseau J, Foster MK, Hunniford VT, Cobey KD, Brehaut JC, Ilkow C, Montroy J, Cardenas A, Sharif A, Jeffers MS, Fergusson DA. Identifying barriers and enablers to rigorous conduct and reporting of preclinical laboratory studies. Plos Biology. 21: e3001932. PMID 36603053 DOI: 10.1371/journal.pbio.3001932  0.771
2022 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. [The PRISMA 2020 statement: an updated guideline for reporting systematic reviewsDeclaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas]. Revista Panamericana De Salud Publica = Pan American Journal of Public Health. 46: e112. PMID 36601438 DOI: 10.26633/RPSP.2022.112  0.382
2022 Kekre N, Hay KA, Webb JR, Mallick R, Balasundaram M, Sigrist MK, Clement AM, Nielsen JS, Quizi J, Yung E, Brown SD, Dreolini L, Waller DD, Smazynski J, Gierc NS, ... ... Lalu MM, et al. CLIC-01: Manufacture and distribution of non-cryopreserved CAR-T cells for patients with CD19 positive hematologic malignancies. Frontiers in Immunology. 13: 1074740. PMID 36601119 DOI: 10.3389/fimmu.2022.1074740  0.545
2022 Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS. Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? Cytotherapy. PMID 36333234 DOI: 10.1016/j.jcyt.2022.10.003  0.622
2022 Roberts DJ, Mor R, Rosen MN, Talarico R, Lalu MM, Jerath A, Wijeysundera DN, McIsaac DI. Hospital-, Anesthesiologist-, Surgeon-, and Patient-Level Variations in Neuraxial Anesthesia Use for Lower Limb Revascularization Surgery: A Population-Based Cross-Sectional Study. Anesthesia and Analgesia. PMID 36219577 DOI: 10.1213/ANE.0000000000006232  0.281
2022 Grudzinski AL, Aucoin S, Talarico R, Moloo H, Lalu MM, McIsaac DI. Measuring the Predictive Accuracy of Preoperative Clinical Frailty Instruments Applied to Electronic Health Data in Older Patients Having Emergency General Surgery: A Retrospective Cohort Study. Annals of Surgery. 278: e341-e348. PMID 36134577 DOI: 10.1097/SLA.0000000000005718  0.258
2022 Lalu MM, Albert MA, Cobey KD. Peering into the dark corners of knowledge synthesis to understand the influence of predatory journals on systematic reviews. Journal of Clinical Epidemiology. PMID 36115546 DOI: 10.1016/j.jclinepi.2022.09.005  0.717
2022 Wilson M, Thavorn K, Hawrysh T, Graham ID, Atkins H, Kekre N, Coyle D, Lalu MM, Fergusson DA, Chan KKW, Ollendorf DA, Presseau J. Engaging Patients and Caregivers in an Early Health Economic Evaluation: Discerning Treatment Value Based on Lived Experience. Pharmacoeconomics. PMID 36071263 DOI: 10.1007/s40273-022-01180-4  0.535
2022 Grudzinski AL, Aucoin S, Talarico R, Moloo H, Lalu MM, McIsaac DI. Comparing the predictive accuracy of frailty instruments applied to preoperative electronic health data for adults undergoing noncardiac surgery. British Journal of Anaesthesia. 129: 506-514. PMID 36031416 DOI: 10.1016/j.bja.2022.07.019  0.261
2022 Evans JM, Peever A, Grudniewicz A, McDonald B, Mendelson AA, Lalu MM. On the same page? A qualitative study protocol on collaboration in a multi-laboratory preclinical study. Plos One. 17: e0273077. PMID 36006928 DOI: 10.1371/journal.pone.0273077  0.344
2022 Hladkowicz E, Dorrance K, Bryson GL, Forster A, Gagne S, Huang A, Lalu MM, Lavallée LT, Moloo H, Squires J, McIsaac DI. Identifying barriers and facilitators to routine preoperative frailty assessment: a qualitative interview study. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 35978162 DOI: 10.1007/s12630-022-02298-x  0.296
2022 Kirkham AM, Bailey AJM, Monaghan M, Shorr R, Lalu MM, Fergusson DA, Allan DS. Updated Living Systematic Review and Meta-analysis of Controlled Trials of Mesenchymal Stromal Cells to Treat COVID-19: A Framework for Accelerated Synthesis of Trial Evidence for Rapid Approval-FASTER Approval. Stem Cells Translational Medicine. PMID 35758400 DOI: 10.1093/stcltm/szac038  0.636
2022 Fox G, Fergusson DA, Nicholls SG, Smith M, Stacey D, Lalu MM. Recognizing patient partner contributions to health research: a mixed methods research protocol. Research Involvement and Engagement. 8: 24. PMID 35668479 DOI: 10.1186/s40900-022-00354-w  0.794
2022 Renesme L, Pierro M, Cobey KD, Mital R, Nangle K, Shorr R, Lalu MM, Thébaud B. Definition and Characteristics of Mesenchymal Stromal Cells in Preclinical and Clinical Studies: A Scoping Review. Stem Cells Translational Medicine. 11: 44-54. PMID 35641170 DOI: 10.1093/stcltm/szab009  0.444
2022 Feng S, van Walraven C, Lalu MM, Moloo H, Musselman R, McIsaac DI. Derivation and external validation of a 30-day mortality risk prediction model for older patients having emergency general surgery. British Journal of Anaesthesia. 129: 33-40. PMID 35597622 DOI: 10.1016/j.bja.2022.04.007  0.28
2022 Fox G, Fergusson DA, Foster M, Hawrysh T, Dupont S, Walling DJ, Irwin M, Kekre N, Presseau J, Castillo G, Montroy J, Lalu MM. Building a Platform for Meaningful Patient Partnership to Accelerate "Bench-to-Bedside" Translation of Promising New Therapies. Healthcare Quarterly (Toronto, Ont.). 24: 74-79. PMID 35467515 DOI: 10.12927/hcq.2022.26770  0.795
2022 Foster M, Fergusson DA, Hunniford V, Cardenas A, Castillo G, Yaworsky J, Mazer CD, Devereaux PJ, McIsaac DI, Stewart DJ, Presseau J, Lalu MM. Understanding potential barriers and enablers to a perioperative early phase cell therapy trial. Cytotherapy. PMID 35396169 DOI: 10.1016/j.jcyt.2021.08.008  0.783
2022 Brandts-Longtin O, Lalu MM, Adie EA, Albert MA, Almoli E, Almoli F, Bryson GL, Dony C, Dunleavy D, Grudniewicz A, Lehmann C, Lhoest R, Moher D, Montroy J, Pitts M, et al. Assessing the impact of predatory journals on policy and guidance documents: a cross-sectional study protocol. Bmj Open. 12: e059445. PMID 35379645 DOI: 10.1136/bmjopen-2021-059445  0.713
2022 McIsaac DI, Montroy J, Gagne S, Johnson C, Ernst J, Halman S, Oake J, Chan J, Madden S, Feng S, Moody M, Simard CG, Taljaard M, Foster M, Fergusson DA, ... Lalu MM, et al. Correction: Implementation of the Canadian Cardiovascular Society guidelines for perioperative risk assessment and management: an interrupted time series study. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 35318611 DOI: 10.1007/s12630-022-02246-9  0.533
2022 Grudzinski AL, Sun B, Zhang M, Crnic A, Djokhdem AH, Hanna M, Montroy J, Duggan LV, Hamilton GM, Fergusson DA, Boet S, McIsaac DI, Lalu MM. Correction to: Airway recommendations for perioperative patients during the COVID-19 pandemic: a scoping review. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 35318610 DOI: 10.1007/s12630-022-02244-x  0.587
2022 Kirkham AM, Monaghan M, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS. Mesenchymal stem/stromal cell-based therapies for COVID-19: First iteration of a living systematic review and meta-analysis: MSCs and COVID-19. Cytotherapy. PMID 35219584 DOI: 10.1016/j.jcyt.2021.12.001  0.584
2022 Renesme L, Cobey KD, Lalu MM, Thébaud B. A systematic approach to enhance transparency in mesenchymal stromal cell research. Cytotherapy. 24: 674-675. PMID 35177339 DOI: 10.1016/j.jcyt.2021.12.011  0.342
2022 Haddad T, Mulpuru S, Salter I, Hladkowicz E, Des Autels K, Gagne S, Bryson GL, McCartney CJL, Huang A, Huang S, Forster A, van Walraven C, Kyeremanteng K, Fernando SM, Nagpal S, ... ... Lalu MM, et al. Development and evaluation of an evidence-based, theory-grounded online Clinical Frailty Scale tutorial. Age and Ageing. 51. PMID 35136898 DOI: 10.1093/ageing/afab258  0.32
2022 Grudzinski AL, Sun B, Zhang M, Crnic A, Djokhdem AH, Hanna M, Montroy J, Duggan LV, Hamilton GM, Fergusson DA, Boet S, McIsaac DI, Lalu MM. Airway recommendations for perioperative patients during the COVID-19 pandemic: a scoping review. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 35112304 DOI: 10.1007/s12630-022-02199-z  0.582
2022 Abdellatif S, Hladkowicz E, Lalu MM, Boet S, Gagne S, McIsaac DI. Patient prioritization of routine and patient-reported postoperative outcome measures: a prospective, nested cross-sectional study. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 35099774 DOI: 10.1007/s12630-022-02191-7  0.291
2022 Shaw JF, Mulpuru S, Kendzerska T, Moloo H, Martel G, Eskander A, Lalu MM, McIsaac DI. Association between frailty and patient outcomes after cancer surgery: a population-based cohort study. British Journal of Anaesthesia. PMID 35034792 DOI: 10.1016/j.bja.2021.11.035  0.245
2021 Patel A, Zhang M, Liao G, Karkache W, Montroy J, Fergusson DA, Khadaroo RG, Tran DTT, McIsaac DI, Lalu MM. A Systematic Review and Meta-Analysis Examining the Impact of Age on Perioperative Inflammatory Biomarkers. Anesthesia and Analgesia. PMID 34962902 DOI: 10.1213/ANE.0000000000005832  0.567
2021 Renesme L, Cobey KD, Le M, Lalu MM, Thebaud B. Establishment of a consensus definition for mesenchymal stromal cells (MSC) and reporting guidelines for clinical trials of MSC therapy: a modified Delphi study protocol. Bmj Open. 11: e054740. PMID 34620674 DOI: 10.1136/bmjopen-2021-054740  0.416
2021 Tieu A, Hu K, Gnyra C, Montroy J, Fergusson DA, Allan DS, Stewart DJ, Thébaud B, Lalu MM. Mesenchymal stromal cell extracellular vesicles as therapy for acute and chronic respiratory diseases: A meta-analysis. Journal of Extracellular Vesicles. 10: e12141. PMID 34596349 DOI: 10.1002/jev2.12141  0.792
2021 McGillion MH, Parlow J, Borges FK, Marcucci M, Jacka M, Adili A, Lalu MM, Ouellette C, Bird M, Ofori S, Roshanov PS, Patel A, Yang H, O'Leary S, Tandon V, et al. Post-discharge after surgery Virtual Care with Remote Automated Monitoring-1 (PVC-RAM-1) technology versus standard care: randomised controlled trial. Bmj (Clinical Research Ed.). 374: n2209. PMID 34593374 DOI: 10.1136/bmj.n2209  0.228
2021 Kirkham AM, Monaghan M, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS. Mesenchymal stromal cells as a therapeutic intervention for COVID-19: a living systematic review and meta-analysis protocol. Systematic Reviews. 10: 249. PMID 34526123 DOI: 10.1186/s13643-021-01803-5  0.615
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Revista Espanola De Cardiologia (English Ed.). 74: 790-799. PMID 34446261 DOI: 10.1016/j.rec.2021.07.010  0.382
2021 Wilson M, Thavorn K, Hawrysh T, Graham ID, Atkins H, Kekre N, Coyle D, Lalu MM, Fergusson DA, Chan KK, Ollendorf DA, Presseau J. Stakeholder engagement in economic evaluation: Protocol for using the nominal group technique to elicit patient, healthcare provider, and health system stakeholder input in the development of an early economic evaluation model of chimeric antigen receptor T-cell therapy. Bmj Open. 11: e046707. PMID 34385243 DOI: 10.1136/bmjopen-2020-046707  0.575
2021 Kirkham AM, Bailey AJM, Tieu A, Maganti HB, Montroy J, Shorr R, Campbell TM, Fergusson DA, Lalu MM, Elmoazzen H, Allan DS. MSC-Derived Extracellular Vesicles in Preclinical Animal Models of Bone Injury: A Systematic Review and Meta-Analysis. Stem Cell Reviews and Reports. PMID 34313927 DOI: 10.1007/s12015-021-10208-9  0.784
2021 Fox G, Fergusson DA, Daham Z, Youssef M, Foster M, Poole E, Sharif A, Richards DP, Hendrick K, Mendelson AA, Macala KF, Monfaredi Z, Montroy J, Fiest KM, Presseau J, ... Lalu MM, et al. Patient engagement in preclinical laboratory research: A scoping review. Ebiomedicine. 70: 103484. PMID 34280783 DOI: 10.1016/j.ebiom.2021.103484  0.79
2021 Zhang M, Montroy J, Sharma R, Fergusson DA, Mendelson AA, Macala KF, Bourque SL, Schlechte JM, Eng MK, McDonald B, Gill SE, Fiest KM, Liaw PC, Fox-Robichaud A, Lalu MM. The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis. Critical Care Explorations. 3: e0433. PMID 34151276 DOI: 10.1097/CCE.0000000000000433  0.582
2021 Laflamme M, Haghbayan H, Lalu MM, Zarychanski R, Lauzier F, Boutin A, Macleod MR, Fergusson DA, Moore L, Costerousse O, Lacroix J, Wellington C, Hutchison J, Turgeon AF. Red blood cell transfusion in animal models of acute brain injuries: a systematic review protocol. Systematic Reviews. 10: 177. PMID 34127055 DOI: 10.1186/s13643-021-01703-8  0.603
2021 McIsaac DI, Montroy J, Gagne S, Johnson C, Ernst J, Halman S, Oake J, Chan J, Madden S, Feng S, Moody M, Simard CG, Taljaard M, Foster M, Fergusson DA, ... Lalu MM, et al. Implementation of the Canadian Cardiovascular Society guidelines for perioperative risk assessment and management: an interrupted time series study. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 34031808 DOI: 10.1007/s12630-021-02026-x  0.555
2021 Douvris A, Burger D, Rodriguez RA, Clark EG, Viñas J, Lalu MM, Shorr R, Burns KD. MicroRNA in Human Acute Kidney Injury: A Systematic Review Protocol. Canadian Journal of Kidney Health and Disease. 8: 20543581211009999. PMID 33996109 DOI: 10.1177/20543581211009999  0.252
2021 Bastin DJ, Khan ST, Montroy J, Kennedy MA, Forbes N, Martel AB, Baker L, Gresham L, Boucher DM, Wong B, Shorr R, Diallo JS, Fergusson DA, Lalu MM, Auer RC, et al. Safety and efficacy of autologous whole cell vaccines in hematologic malignancies: A systematic review and meta-analysis. Hematological Oncology. PMID 33963789 DOI: 10.1002/hon.2875  0.576
2021 Hunniford VT, Montroy J, Fergusson DA, Avey MT, Wever KE, McCann SK, Foster M, Fox G, Lafreniere M, Ghaly M, Mannell S, Godwinska K, Gentles A, Selim S, MacNeil J, ... ... Lalu MM, et al. Epidemiology and reporting characteristics of preclinical systematic reviews. Plos Biology. 19: e3001177. PMID 33951050 DOI: 10.1371/journal.pbio.3001177  0.785
2021 Bailey AJM, Li H, Kirkham AM, Tieu A, Maganti HB, Shorr R, Fergusson DA, Lalu MM, Elomazzen H, Allan DS. MSC-Derived Extracellular Vesicles to Heal Diabetic Wounds: a Systematic Review and Meta-Analysis of Preclinical Animal Studies. Stem Cell Reviews and Reports. PMID 33893619 DOI: 10.1007/s12015-021-10164-4  0.791
2021 Bailey AJM, Tieu A, Gupta M, Slobodian M, Shorr R, Ramsay T, Rodriguez RA, Fergusson DA, Lalu MM, Allan DS. Mesenchymal Stromal Cell-derived Extracellular Vesicles in Preclinical Animal Models of Tumor Growth: Systematic Review and Meta-analysis. Stem Cell Reviews and Reports. PMID 33860455 DOI: 10.1007/s12015-021-10163-5  0.784
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. International Journal of Surgery (London, England). 105906. PMID 33789826 DOI: 10.1016/j.ijsu.2021.105906  0.381
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Journal of Clinical Epidemiology. PMID 33789819 DOI: 10.1016/j.jclinepi.2021.03.001  0.381
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Bmj (Clinical Research Ed.). 372: n71. PMID 33782057 DOI: 10.1136/bmj.n71  0.367
2021 Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. Bmj (Clinical Research Ed.). 372: n160. PMID 33781993 DOI: 10.1136/bmj.n160  0.353
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Systematic Reviews. 10: 89. PMID 33781348 DOI: 10.1186/s13643-021-01626-4  0.367
2021 Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Plos Medicine. 18: e1003583. PMID 33780438 DOI: 10.1371/journal.pmed.1003583  0.37
2021 Castillo G, Lalu MM, Asad S, Foster M, Kekre N, Fergusson DA, Hawrysh T, Atkins H, Thavorn K, Montroy J, Schwartz S, Holt RA, Broady R, Presseau J. Navigating choice in the face of uncertainty: using a theory informed qualitative approach to identifying potential patient barriers and enablers to participating in an early phase chimeric antigen receptor T (CAR-T) cell therapy trial. Bmj Open. 11: e043929. PMID 33741670 DOI: 10.1136/bmjopen-2020-043929  0.573
2021 Castillo G, Mack DR, Lalu MM, Singleton R, Fergusson DA, Stintzi A, Harrison M, Presseau J. Factors contributing to fidelity in a pilot trial of individualized resistant starches for pediatric inflammatory bowel disease: a fidelity study protocol. Pilot and Feasibility Studies. 7: 75. PMID 33741062 DOI: 10.1186/s40814-021-00815-1  0.584
2021 Mendelson AA, Lansdell C, Fox-Robichaud AE, Liaw P, Arora J, Cailhier JF, Cepinskas G, Charbonney E, Dos Santos C, Dwivedi D, Ellis CG, Fergusson D, Fiest K, Gill SE, Hendrick K, ... ... Lalu MM, et al. National Preclinical Sepsis Platform: developing a framework for accelerating innovation in Canadian sepsis research. Intensive Care Medicine Experimental. 9: 14. PMID 33738642 DOI: 10.1186/s40635-020-00366-4  0.808
2021 McGillion MH, Parlow J, Borges FK, Marcucci M, Jacka M, Adili A, Lalu MM, Yang H, Patel A, O'Leary S, Tandon V, Hamilton GM, Mrkobrada M, Ouellette C, Bird M, et al. Post Discharge after Surgery Virtual Care with Remote Automated Monitoring Technology (PVC-RAM): protocol for a randomized controlled trial. Cmaj Open. 9: E142-E148. PMID 33653769 DOI: 10.9778/cmajo.20200176  0.267
2021 McIsaac DI, Aucoin SD, Bryson GL, Hamilton GM, Lalu MM. Complications as a Mediator of the Perioperative Frailty-Mortality Association. Anesthesiology. 134: 577-587. PMID 33529334 DOI: 10.1097/ALN.0000000000003699  0.226
2021 Ripley AJ, Jeffers MS, McDonald MW, Montroy J, Dykes A, Fergusson DA, Silasi G, Lalu MM, Corbett D. Neuroprotection by Remote Ischemic Conditioning in Rodent Models of Focal Ischemia: a Systematic Review and Meta-Analysis. Translational Stroke Research. PMID 33405011 DOI: 10.1007/s12975-020-00882-1  0.791
2021 Zhang MQ, Macala KF, Fox-Robichaud A, Mendelson AA, Lalu MM. Sex- and Gender-Dependent Differences in Clinical and Preclinical Sepsis. Shock (Augusta, Ga.). 56: 178-187. PMID 33399356 DOI: 10.1097/SHK.0000000000001717  0.359
2020 Fergusson DA, Lalu MM. Mind the evidence gap: The need for trials in the prevention and management of perioperative anemia in noncardiac surgery. Transfusion. 60: 2168-2170. PMID 33615497 DOI: 10.1111/trf.16103  0.556
2020 Yu M, Montroy J, Fergusson D, Lalu M, Kimmelman J. Systematic and narrative review lead experts to different cancer trial predictions: a randomized trial. Journal of Clinical Epidemiology. PMID 33346013 DOI: 10.1016/j.jclinepi.2020.12.006  0.609
2020 McGinn R, Fergusson DA, Stewart DJ, Kristof AS, Barron CC, Thebaud B, McIntyre L, Stacey D, Liepmann M, Dodelet-Devillers A, Zhang H, Renlund R, Lilley E, Downey GP, Brown EG, ... ... Lalu MM, et al. Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. Critical Care Medicine. PMID 33332817 DOI: 10.1097/CCM.0000000000004734  0.688
2020 Roberts DJ, Nagpal SK, Kubelik D, Brandys T, Stelfox HT, Lalu MM, Forster AJ, McCartney CJ, McIsaac DI. Association between neuraxial anaesthesia or general anaesthesia for lower limb revascularisation surgery in adults and clinical outcomes: population based comparative effectiveness study. Bmj (Clinical Research Ed.). 371: m4104. PMID 33239330 DOI: 10.1136/bmj.m4104  0.28
2020 Montroy J, Berjawi R, Lalu MM, Podolsky E, Peixoto C, Sahin L, Stintzi A, Mack D, Fergusson DA. The effects of resistant starches on inflammatory bowel disease in preclinical and clinical settings: a systematic review and meta-analysis. Bmc Gastroenterology. 20: 372. PMID 33167889 DOI: 10.1186/s12876-020-01516-4  0.569
2020 Gupta M, Tieu A, Slobodian M, Shorr R, Burger D, Lalu MM, Allan DS. Preclinical Studies of MSC-Derived Extracellular Vesicles to Treat or Prevent Graft Versus Host Disease: a Systematic Review of the Literature. Stem Cell Reviews and Reports. PMID 33159616 DOI: 10.1007/s12015-020-10058-x  0.766
2020 Lalu MM, Montroy J, Begley CG, Bubela T, Hunniford V, Ripsman D, Wesch N, Kimmelman J, Macleod M, Moher D, Tieu A, Sikora L, Fergusson DA. Identifying and understanding factors that affect the translation of therapies from the laboratory to patients: a study protocol. F1000research. 9: 485. PMID 33123348 DOI: 10.12688/F1000Research.23663.1  0.81
2020 Foster M, Fergusson DA, Hawrysh T, Presseau J, Kekre N, Schwartz S, Castillo G, Asad S, Fox G, Atkins H, Thavorn K, Montroy J, Holt RA, Monfaredi Z, Lalu MM. Partnering with patients to get better outcomes with chimeric antigen receptor T-cell therapy: towards engagement of patients in early phase trials. Research Involvement and Engagement. 6: 61. PMID 33072399 DOI: 10.1186/s40900-020-00230-5  0.803
2020 Zheng K, Liao G, Lalu MM, Tinmouth A, Fergusson DA, Allan DS. A Scoping Review of Registered Clinical Trials of Convalescent Plasma for COVID-19 and a Framework for Accelerated Synthesis of Trial Evidence (FAST Evidence). Transfusion Medicine Reviews. PMID 32771272 DOI: 10.1016/j.tmrv.2020.06.005  0.613
2020 Tieu A, Lalu MM, Slobodian M, Gnyra C, Fergusson DA, Montroy J, Burger D, Stewart DJ, Allan DS. An Analysis of Mesenchymal Stem Cell-Derived Extracellular Vesicles for Preclinical Use. Acs Nano. PMID 32697573 DOI: 10.1021/Acsnano.0C01363  0.813
2020 Khalife R, Montroy J, Grigor EJM, Fergusson DA, Atkins H, Seftel M, Presseau J, Thavorn K, Holt RA, Hay K, Lalu MM, Kekre N. Building Canadian capacity for CAR-T cells in relapsed/refractory acute lymphoblastic leukaemia: a retrospective cohort study. British Journal of Haematology. PMID 32688454 DOI: 10.1111/Bjh.16940  0.531
2020 Liao G, Zheng K, Lalu MM, Fergusson DA, Allan DS. A Scoping Review of Registered Clinical Trials of Cellular Therapy for COVID-19 and a Framework for Accelerated Synthesis of Trial Evidence-FAST Evidence. Transfusion Medicine Reviews. PMID 32684483 DOI: 10.1016/J.Tmrv.2020.06.001  0.637
2020 Ripsman D, Fergusson DA, Montroy J, Auer RC, Huang JW, Dobriyal A, Wesch N, Carrier M, Lalu MM. A systematic review on the efficacy and safety of low molecular weight heparin as an anticancer therapeutic in preclinical animal models. Thrombosis Research. 195: 103-113. PMID 32683148 DOI: 10.1016/J.Thromres.2020.07.008  0.594
2020 Tieu A, Stewart DJ, Lalu MM. Mesenchymal Stem Cell-Derived Extracellular Vesicles: Good Things Come in Small Packages. Critical Care Medicine. 48: 1095-1097. PMID 32568911 DOI: 10.1097/CCM.0000000000004368  0.765
2020 Poulton A, Shaw JF, Nguyen F, Wong C, Lampron J, Tran A, Lalu MM, McIsaac DI. The Association of Frailty With Adverse Outcomes After Multisystem Trauma: A Systematic Review and Meta-analysis. Anesthesia and Analgesia. 130: 1482-1492. PMID 32384338 DOI: 10.1213/ANE.0000000000004687  0.347
2020 Cukier S, Helal L, Rice DB, Pupkaite J, Ahmadzai N, Wilson M, Skidmore B, Lalu MM, Moher D. Checklists to detect potential predatory biomedical journals: a systematic review. Bmc Medicine. 18: 104. PMID 32375818 DOI: 10.1186/s12916-020-01566-1  0.33
2020 Montroy J, Lalu MM, Auer RC, Grigor E, Mazzarello S, Carrier M, Kimmelman J, Fergusson DA. The Efficacy and Safety of Low Molecular Weight Heparin Administration to Improve Survival of Cancer Patients: A Systematic Review and Meta-Analysis. Thrombosis and Haemostasis. 120: 832-846. PMID 32369854 DOI: 10.1055/S-0040-1709712  0.592
2020 Mazzarello S, McIsaac DI, Beattie WS, Fergusson DA, Lalu MM. Risk Factors for Failure to Rescue in Myocardial Infarction after Noncardiac Surgery: A Cohort Study. Anesthesiology. PMID 32349069 DOI: 10.1097/Aln.0000000000003330  0.534
2020 Cobey KD, Rice DB, Lalu MM, Abramowitz D, Ahmadzai N, Cunningham H, Ayala AP, Raffoul H, Khan F, Shamseer L, Moher D. Stress testing journals: a quasi-experimental study of rejection rates of a previously published paper. Bmc Medicine. 18: 88. PMID 32312313 DOI: 10.1186/s12916-020-01550-9  0.329
2020 Lalu MM, Foster M, Presseau J, Dowlatshahi D, Castillo G, Cardenas A, Tam W, Zlepnig J, Timpson D, Dong YY, Juneau P, Fergusson DA. What are potential barriers and enablers to patient and physician participation in Canadian cell therapy trials for stroke? A stakeholder interview study. Bmj Open. 10: e034354. PMID 32198301 DOI: 10.1136/Bmjopen-2019-034354  0.592
2019 Tieu A, Slobodian M, Fergusson DA, Montroy J, Burger D, Stewart DJ, Shorr R, Allan DS, Lalu MM. Methods and efficacy of extracellular vesicles derived from mesenchymal stromal cells in animal models of disease: a preclinical systematic review protocol. Systematic Reviews. 8: 322. PMID 31831057 DOI: 10.1186/S13643-019-1242-Y  0.796
2019 Grudniewicz A, Moher D, Cobey KD, Bryson GL, Cukier S, Allen K, Ardern C, Balcom L, Barros T, Berger M, Ciro JB, Cugusi L, Donaldson MR, Egger M, Graham ID, ... ... Lalu MM, et al. Predatory journals: no definition, no defence. Nature. 576: 210-212. PMID 31827288 DOI: 10.1038/D41586-019-03759-Y  0.291
2019 Lalu MM, Montroy J, Dowlatshahi D, Hutton B, Juneau P, Wesch N, Y Zhang S, McGinn R, Corbett D, Stewart DJ, A Fergusson D. From the Lab to Patients: a Systematic Review and Meta-Analysis of Mesenchymal Stem Cell Therapy for Stroke. Translational Stroke Research. PMID 31654281 DOI: 10.1007/S12975-019-00736-5  0.69
2019 Hamilton GM, Lalu MM, Ramlogan R, Bryson GL, Abdallah FW, McCartney CJL, McIsaac DI. A Population-based Comparative Effectiveness Study of Peripheral Nerve Blocks for Hip Fracture Surgery. Anesthesiology. 131: 1025-1035. PMID 31634246 DOI: 10.1097/ALN.0000000000002947  0.26
2019 McIsaac DI, Harris EP, Hladkowicz E, Moloo H, Lalu MM, Bryson GL, Huang A, Joanisse J, Hamilton GM, Forster AJ, van Walraven C. Prospective Comparison of Preoperative Predictive Performance Between 3 Leading Frailty Instruments. Anesthesia and Analgesia. PMID 31569165 DOI: 10.1213/ANE.0000000000004475  0.27
2019 Mazzarello S, McIsaac DI, Montroy J, Fergusson DA, Yateem D, Devereaux PJ, Lalu MM. Postoperative shared-care for patients undergoing non-cardiac surgery: a systematic review and meta-analysis. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 31290119 DOI: 10.1007/S12630-019-01433-5  0.583
2019 Fergusson DA, Wesch NL, Leung GJ, MacNeil JL, Conic I, Presseau J, Cobey KD, Diallo JS, Auer R, Kimmelman J, Kekre N, El-Sayes N, Krishnan R, Keller BA, Ilkow C, ... Lalu MM, et al. Assessing the Completeness of Reporting in Preclinical Oncolytic Virus Therapy Studies. Molecular Therapy Oncolytics. 14: 179-187. PMID 31276026 DOI: 10.1016/J.Omto.2019.05.004  0.632
2019 Harris EP, MacDonald DB, Boland L, Boet S, Lalu MM, McIsaac DI. Personalized perioperative medicine: a scoping review of personalized assessment and communication of risk before surgery. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 31240608 DOI: 10.1007/S12630-019-01432-6  0.286
2019 Fergusson DA, Avey MT, Barron CC, Bocock M, Biefer KE, Boet S, Bourque SL, Conic I, Chen K, Dong YY, Fox GM, George RB, Goldenberg NM, Gragasin FS, Harsha P, ... ... Lalu MM, et al. Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature. Plos One. 14: e0215221. PMID 31120888 DOI: 10.1371/Journal.Pone.0215221  0.8
2019 Lalu MM, Shamseer L, Cobey KD, Moher D. How stakeholders can respond to the rise of predatory journals. Nature Human Behaviour. 1: 852-855. PMID 31024187 DOI: 10.1038/s41562-017-0257-4  0.272
2019 Guillot M, Asad S, Lalu MM, Lemyre B, Castillo G, Thébaud B, Presseau J. So You Want to Give Stem Cells to Babies? Neonatologists and Parents' Views to Optimize Clinical Trials. The Journal of Pediatrics. 210: 41-47.e1. PMID 31005276 DOI: 10.1016/j.jpeds.2019.03.005  0.314
2019 Grigor EJM, Fergusson D, Kekre N, Montroy J, Atkins H, Seftel MD, Daugaard M, Presseau J, Thavorn K, Hutton B, Holt RA, Lalu MM. Risks and Benefits of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Cancer: A Systematic Review and Meta-Analysis. Transfusion Medicine Reviews. PMID 30948292 DOI: 10.1016/J.Tmrv.2019.01.005  0.588
2019 Lalu MM, Fergusson DA, Cheng W, Avey MT, Corbett D, Dowlatshahi D, Macleod MR, Sena ES, Moher D, Shorr R, McCann SK, Gray LJ, Hill MD, O'Connor A, Thayer K, et al. Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis. F1000research. 8: 11. PMID 30906535 DOI: 10.12688/F1000Research.15869.1  0.796
2019 Cobey KD, Grudniewicz A, Lalu MM, Rice DB, Raffoul H, Moher D. Knowledge and motivations of researchers publishing in presumed predatory journals: a survey. Bmj Open. 9: e026516. PMID 30904874 DOI: 10.1136/bmjopen-2018-026516  0.354
2019 Suen CM, Stewart DJ, Montroy J, Welsh C, Levac B, Wesch N, Zhai A, Fergusson D, McIntyre L, Lalu MM. Regenerative cell therapy for pulmonary arterial hypertension in animal models: a systematic review. Stem Cell Research & Therapy. 10: 75. PMID 30841915 DOI: 10.1186/S13287-019-1172-6  0.664
2019 Mendis N, Hamilton GM, McIsaac DI, Fergusson DA, Wunsch H, Dubois D, Montroy J, Chassé M, Turgeon AF, McIntyre L, McDonald H, Yang H, Sampson SD, McCartney CJL, Shorr R, ... ... Lalu MM, et al. A Systematic Review of the Impact of Surgical Special Care Units on Patient Outcomes and Health Care Resource Utilization. Anesthesia and Analgesia. PMID 30676348 DOI: 10.1213/Ane.0000000000003942  0.551
2019 Millington SJ, Lalu MM, Boivin M, Koenig S. Better with Ultrasound: Subclavian Central Venous Catheter Insertion. Chest. PMID 30610849 DOI: 10.1016/j.chest.2018.12.007  0.285
2018 Boet S, Etherington N, Nicola D, Beck A, Bragg S, Carrigan ID, Larrigan S, Mendonca CT, Miao I, Postonogova T, Walker B, De Wit J, Mohamed K, Balaa N, Lalu MM, et al. Anesthesia interventions that alter perioperative mortality: a scoping review. Systematic Reviews. 7: 218. PMID 30497505 DOI: 10.1186/S13643-018-0863-X  0.387
2018 Lalu MM, Mazzarello S, Zlepnig J, Dong YYR, Montroy J, McIntyre L, Devereaux PJ, Stewart DJ, David Mazer C, Barron CC, McIsaac DI, Fergusson DA. Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis. Stem Cells Translational Medicine. PMID 30255989 DOI: 10.1002/Sctm.18-0120  0.714
2018 Cobey KD, Lalu MM, Skidmore B, Ahmadzai N, Grudniewicz A, Moher D. What is a predatory journal? A scoping review. F1000research. 7: 1001. PMID 30135732 DOI: 10.12688/f1000research.15256.1  0.348
2018 Abbott TEF, Fowler AJ, Pelosi P, Gama de Abreu M, Møller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM. A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia. 120: 1066-1079. PMID 29661384 DOI: 10.1016/J.Bja.2018.02.007  0.37
2017 Grigor EJM, Fergusson DA, Haggar F, Kekre N, Atkins H, Shorr R, Holt RA, Hutton B, Ramsay T, Seftel M, Jonker D, Daugaard M, Thavorn K, Presseau J, Lalu MM. Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in patients with haematological and solid malignancies: protocol for a systematic review and meta-analysis. Bmj Open. 7: e019321. PMID 29288188 DOI: 10.1136/Bmjopen-2017-019321  0.574
2017 McIsaac DI, Jen T, Mookerji N, Patel A, Lalu MM. Interventions to improve the outcomes of frail people having surgery: A systematic review. Plos One. 12: e0190071. PMID 29287123 DOI: 10.1371/journal.pone.0190071  0.303
2017 Lavallée C, Ayoub C, Mansour A, Lambert J, Lebon JS, Lalu MM, Denault A. Subclavian and axillary vessel anatomy: a prospective observational ultrasound study. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 29209928 DOI: 10.1007/s12630-017-1032-8  0.242
2017 Barron CC, Lalu MM, Stewart DJ, Fergusson D, Yang H, Moher D, Liu P, Mazer D, Devereaux PJ, McIntyre L. Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol. Systematic Reviews. 6: 226. PMID 29116020 DOI: 10.1186/S13643-017-0601-9  0.709
2017 Moher D, Shamseer L, Cobey KD, Lalu MM, Galipeau J, Avey MT, Ahmadzai N, Alabousi M, Barbeau P, Beck A, Daniel R, Frank R, Ghannad M, Hamel C, Hersi M, et al. Stop this waste of people, animals and money. Nature. 549: 23-25. PMID 28880300 DOI: 10.1038/549023A  0.628
2017 Hoffmann S, de Vries RBM, Stephens ML, Beck NB, Dirven HAAM, Fowle JR, Goodman JE, Hartung T, Kimber I, Lalu MM, Thayer K, Whaley P, Wikoff D, Tsaioun K. A primer on systematic reviews in toxicology. Archives of Toxicology. PMID 28501917 DOI: 10.1007/s00204-017-1980-3  0.407
2017 Hamilton GM, Wheeler K, Di Michele J, Lalu MM, McIsaac DI. A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality. Anesthesiology. PMID 28459734 DOI: 10.1097/ALN.0000000000001660  0.297
2016 Lalu MM, Sullivan KJ, Mei SH, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L. Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial. Elife. 5. PMID 27870924 DOI: 10.7554/Elife.17850  0.735
2016 Avey MT, Moher D, Sullivan KJ, Fergusson D, Griffin G, Grimshaw JM, Hutton B, Lalu MM, Macleod M, Marshall J, Mei SH, Rudnicki M, Stewart DJ, Turgeon AF, McIntyre L, et al. The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research. Plos One. 11: e0166733. PMID 27855228 DOI: 10.1371/Journal.Pone.0166733  0.81
2016 Hall R, Beattie S, Grocott HP, Mazer CD, Turgeon AF, Denault A, Yang H, Lalu MM, George RB, Sampson S, McDonald H. Erratum to: Can we create a Canadian Perioperative Anesthesia Clinical Trials Group? We review the first five years and glimpse into the future. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 27796836 DOI: 10.1007/s12630-016-0765-0  0.354
2016 Hall R, Beattie S, Grocott HP, Mazer CD, Turgeon AF, Denault A, Yang H, Lalu MM, George RB, Sampson S, McDonald H. Can we create a Canadian Perioperative Anesthesia Clinical Trials Group? We review the first five years and glimpse into the future. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie. PMID 27557908 DOI: 10.1007/s12630-016-0719-6  0.354
2016 Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ. Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol. Systematic Reviews. 5: 89. PMID 27225668 DOI: 10.1186/S13643-016-0265-X  0.698
2016 Tone KJ, James TE, Fergusson DA, Tinmouth A, Tay J, Avey MT, Kilty S, Lalu MM. Acquired Factor XIII Inhibitor in Hospitalized and Perioperative Patients: A Systematic Review of Case Reports and Case Series. Transfusion Medicine Reviews. PMID 27167905 DOI: 10.1016/J.Tmrv.2016.04.001  0.761
2016 Samuel GO, Hoffmann S, Wright RA, Lalu MM, Patlewicz G, Becker RA, DeGeorge GL, Fergusson D, Hartung T, Lewis RJ, Stephens ML. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review. Environment International. PMID 27039952 DOI: 10.1016/J.Envint.2016.03.010  0.618
2015 Lalu MM, Barron CC, Fergusson DA. The authors reply. Critical Care Medicine. 43: e475-6. PMID 26376280 DOI: 10.1097/CCM.0000000000001224  0.504
2015 Lalu MM, Fayad A, Ahmed O, Bryson GL, Fergusson DA, Barron CC, Sullivan P, Thompson C. Ultrasound-Guided Subclavian Vein Catheterization: A Systematic Review and Meta-Analysis. Critical Care Medicine. 43: 1498-507. PMID 25803646 DOI: 10.1097/Sa.0000000000000214  0.568
2014 Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, et al. Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol. Systematic Reviews. 3: 48. PMID 24887266 DOI: 10.1186/2046-4053-3-48  0.798
2014 Lalu MM, Barron CC, Stewart DJ, McIntyre LL. Adult stem cells: potential implications for perioperative medicine. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 61: 299-305. PMID 24510734 DOI: 10.1007/s12630-014-0121-1  0.525
2013 Bautista-López NL, Morillo CA, López-Jaramillo P, Quiroz R, Luengas C, Silva SY, Galipeau J, Lalu MM, Schulz R. Matrix metalloproteinases 2 and 9 as diagnostic markers in the progression to Chagas cardiomyopathy. American Heart Journal. 165: 558-66. PMID 23537973 DOI: 10.1016/j.ahj.2013.01.001  0.213
2012 Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ. Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. Plos One. 7: e47559. PMID 23133515 DOI: 10.1371/Journal.Pone.0047559  0.713
2012 Ahmed O, Fayad A, Bryson G, Fergusson D, Lalu MM. Practice guidelines for ultrasound-guided subclavian vein catheterization: analyzing the evidence. Anesthesia & Analgesia. 115: 1251-1252. PMID 23093584 DOI: 10.1213/Ane.0B013E318267Cf46  0.549
2012 Lalu MM, Xu H, Sankaralingam S, Davidge ST. Proteasome inhibition decreases inflammation in human endothelial cells exposed to lipopolysaccharide. Journal of Cardiovascular Pharmacology. 60: 381-9. PMID 22820895 DOI: 10.1097/FJC.0b013e3182657eec  0.484
2012 Lalu MM, McIntyre LL, Stewart DJ. Mesenchymal stromal cells: cautious optimism for their potential role in the treatment of acute lung injury. Critical Care Medicine. 40: 1373-5. PMID 22425851 DOI: 10.1097/CCM.0b013e31824317f7  0.517
2011 Lalu MM. Matrix metalloproteinases: from tadpole tails to critical illness. Critical Care Medicine. 39: 413-4. PMID 21248528 DOI: 10.1097/CCM.0b013e318205c327  0.194
2011 Sankaralingam S, Lalu MM, Xu Y, Davidge ST. Effect of peroxynitrite scavenging on endothelial cells stimulated by plasma from women with preeclampsia: a proteomic approach. Hypertension in Pregnancy. 29: 419-28. PMID 20504167 DOI: 10.3109/10641950903452360  0.471
2010 Cena JJ, Lalu MM, Cho WJ, Chow AK, Bagdan ML, Daniel EE, Castro MM, Schulz R. Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia. American Journal of Physiology. Heart and Circulatory Physiology. 298: H45-51. PMID 19837953 DOI: 10.1152/ajpheart.00273.2009  0.21
2008 Gutierrez FR, Lalu MM, Mariano FS, Milanezi CM, Cena J, Gerlach RF, Santos JE, Torres-Dueñas D, Cunha FQ, Schulz R, Silva JS. Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection. The Journal of Infectious Diseases. 197: 1468-76. PMID 18444803 DOI: 10.1086/587487  0.22
2008 Cena J, Lalu MM, Rosenfelt C, Schulz R. Endothelial dependence of matrix metalloproteinase-mediated vascular hyporeactivity caused by lipopolysaccharide. European Journal of Pharmacology. 582: 116-22. PMID 18242597 DOI: 10.1016/j.ejphar.2007.12.019  0.205
2007 Lalu MM, Xu H, Davidge ST. Matrix metalloproteinases: control of vascular function and their potential role in preeclampsia. Frontiers in Bioscience : a Journal and Virtual Library. 12: 2484-93. PMID 17127257 DOI: 10.2741/2249  0.491
2006 Lalu MM, Cena J, Chowdhury R, Lam A, Schulz R. Matrix metalloproteinases contribute to endotoxin and interleukin-1beta induced vascular dysfunction. British Journal of Pharmacology. 149: 31-42. PMID 16880766 DOI: 10.1038/sj.bjp.0706823  0.203
2006 Sankaralingam S, Arenas IA, Lalu MM, Davidge ST. Preeclampsia: current understanding of the molecular basis of vascular dysfunction. Expert Reviews in Molecular Medicine. 8: 1-20. PMID 16438753 DOI: 10.1017/S1462399406010465  0.477
2006 Giricz Z, Lalu MM, Csonka C, Bencsik P, Schulz R, Ferdinandy P. Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition. The Journal of Pharmacology and Experimental Therapeutics. 316: 154-61. PMID 16166272 DOI: 10.1124/jpet.105.091140  0.218
2005 Lalu MM, Pasini E, Schulze CJ, Ferrari-Vivaldi M, Ferrari-Vivaldi G, Bachetti T, Schulz R. Ischaemia-reperfusion injury activates matrix metalloproteinases in the human heart. European Heart Journal. 26: 27-35. PMID 15615796 DOI: 10.1093/eurheartj/ehi007  0.223
2004 Lalu MM, Csont T, Schulz R. Matrix metalloproteinase activities are altered in the heart and plasma during endotoxemia. Critical Care Medicine. 32: 1332-7. PMID 15187516 DOI: 10.1097/01.ccm.0000127778.16609.ec  0.194
2004 Lalu MM, Gao CQ, Schulz R. Matrix metalloproteinase inhibitors attenuate endotoxemia induced cardiac dysfunction: a potential role for MMP-9. Molecular and Cellular Biochemistry. 251: 61-6. PMID 14575305  0.207
2003 Lalu MM, Wang W, Schulz R. Peroxynitrite in myocardial ischemia-reperfusion injury. Heart Failure Reviews. 7: 359-69. PMID 12379821 DOI: 10.1023/a:1020766502316  0.262
2002 Lalu MM, Csonka C, Giricz Z, Csont T, Schulz R, Ferdinandy P. Preconditioning decreases ischemia/reperfusion-induced release and activation of matrix metalloproteinase-2. Biochemical and Biophysical Research Communications. 296: 937-41. PMID 12200138 DOI: 10.1016/s0006-291x(02)02019-3  0.213
2002 Khadour FH, Panas D, Ferdinandy P, Schulze C, Csont T, Lalu MM, Wildhirt SM, Schulz R. Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1108-15. PMID 12181141 DOI: 10.1152/ajpheart.00549.2001  0.206
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