Igor E. Brodsky, Ph.D.

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Bacterial pathogenicity
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"Igor Brodsky"

Parents

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Stanley Falkow grad student 2004 Stanford
 (Role of Salmonella virulence genes in bacterial resistance to antimicrobial peptides and systemic disease.)
Ruslan Medzhitov post-doc (Chemistry Tree)
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Publications

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Monack DM, Brodsky IE. (2020) Editorial overview: The fortunate students, a tribute to the fortunate professor. Current Opinion in Microbiology
Rosadini CV, Zanoni I, Odendall C, et al. (2015) A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4. Cell Host & Microbe. 18: 682-93
Fonseca DM, Hand TW, Han SJ, et al. (2015) Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity. Cell. 163: 354-66
Zwack EE, Snyder AG, Wynosky-Dolfi MA, et al. (2015) Inflammasome activation in response to the yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD Mbio. 6
Chung LK, Philip NH, Schmidt VA, et al. (2014) IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM. Mbio. 5: e01402-14
Nish SA, Schenten D, Wunderlich FT, et al. (2014) T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 3: e01949
Philip NH, Dillon CP, Snyder AG, et al. (2014) Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 7385-90
Wynosky-Dolfi MA, Snyder AG, Philip NH, et al. (2014) Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome. The Journal of Experimental Medicine. 211: 653-68
Bezbradica JS, Rosenstein RK, DeMarco RA, et al. (2014) A role for the ITAM signaling module in specifying cytokine-receptor functions. Nature Immunology. 15: 333-42
Beiting DP, Peixoto L, Akopyants NS, et al. (2014) Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. Plos One. 9: e88398
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