John R. Murphy, PhD
Affiliations: | 1984 | Microbiology and Molecular Genetics | Harvard Medical School, Boston, MA, United States |
| 1984- | Microbiology | Boston University School of Medicine, Boston, MA |
Area:
molecular biology and molecular genetics of bacterial protein toxinsWebsite:
http://www.bu.edu/neidl/research/researchers/john-r-murphy-ph-d/Google:
"John Richard Murphy"Bio:
http://aem.asm.org/content/24/2/283.short
DOI: 10.1099/00221287-73-2-339
http://www.pnas.org/content/71/1/11.short
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Richard C. Tilton | grad student | 1972 | University of Connecticut Health Center | |
| (Purification and characterization of thiosulfate : cyanide sulfur transferase from Thiobacillus sp. strain IV-85) | ||||
| Alwin M. Pappenheimer, Jr | post-doc | 1972-1974 | Harvard | |
Children
Sign in to add trainee| James Laurence Michel | grad student | 1982 | Harvard Medical School (Chemistry Tree) |
| William R. Bishai | grad student | 1989 | Harvard Medical School |
| Pankaj Kumar | post-doc | 2017- | Johns Hopkins University School of Medicine; NYU Langone Medical center (Chemistry Tree) |
BETA: Related publications
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Publications
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| Parveen S, Shen J, Lun S, et al. (2023) Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nature Communications. 14: 7427 |
| Parveen S, Shen J, Lun S, et al. (2023) Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against . Biorxiv : the Preprint Server For Biology |
| Parveen S, Lun S, Urbanowski ME, et al. (2021) Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells and related cells using a diphtheria toxin-based fusion protein. The Journal of Infectious Diseases |
| Parveen S, Siddharth S, Cheung LS, et al. (2021) Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model. Molecular Oncology |
| Kumar P, Kumar A, Parveen S, et al. (2019) Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy |
| Parveen S, Bishai WR, Murphy JR. (2019) : Diphtheria Toxin, the Operon, and Its Regulation by Fe2 Activation of apo-DtxR. Microbiology Spectrum. 7 |
| Cheung LS, Fu J, Kumar P, et al. (2019) Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America |
| Gupta S, Cheung L, Pokkali S, et al. (2017) Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. The Journal of Infectious Diseases. 215: 1883-1887 |
| Ando M, Manabe YC, Converse PJ, et al. (2003) Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infection and Immunity. 71: 2584-90 |
| Brennan PJ, Terwilliger T, Barry CE, et al. (2002) The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135 |