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R. John Collier

Affiliations: 
1966-1984 Bacteriology University of California, Los Angeles, Los Angeles, CA 
 1984- Microbiology and Immunobiology Harvard University, Cambridge, MA, United States 
Area:
diphtheria toxin
Website:
http://micro.med.harvard.edu/faculty/collier.html
Google:
"R. John Collier"
Bio:

http://www.nasonline.org/member-directory/members/59399.html
http://news.harvard.edu/gazette/story/2005/07/critical-step-traced-in-anthrax-infection/
https://de.wikipedia.org/wiki/R._John_Collier

Cross-listing: Chemistry Tree

Parents

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Alwin M. Pappenheimer, Jr grad student 1964 Harvard
 (Studies on the mode of action of diphtheria toxin)

Children

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Carleen M. Collins grad student (Chemistry Tree)
Jolinda A. Traugh grad student 1970 UCLA (Chemistry Tree)
John J. Mekalanos grad student 1978 UCLA (Microtree)
Bruce L. Kagan grad student 1982-1985 UCLA (Neurotree)
Bryan A. Krantz post-doc 2004-2006 Harvard Medical School (Chemistry Tree)

Collaborators

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Alan Finkelstein collaborator Albert Einstein (Neurotree)
BETA: Related publications

Publications

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Yang N, Liu SM, Marlin S, et al. (2018) Chimeras of anthrax toxin and botulinum neurotoxin as novel analgesic proteins Toxicon. 156: S118
Jiang J, Pentelute BL, Collier RJ, et al. (2016) 2.9-Å Resolution Structure of Anthrax Protective Antigen Pore Determined by Cryo Electron Microscopy Biophysical Journal. 110: 158a
Jiang J, Pentelute BL, Collier RJ, et al. (2015) Atomic structure of anthrax protective antigen pore elucidates toxin translocation. Nature. 521: 545-9
Sharma O, Collier RJ. (2014) Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore. Biochemistry. 53: 6934-40
Naik S, Brock S, Akkaladevi N, et al. (2013) Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance. Biochemistry. 52: 6335-47
Slater LH, Hett EC, Mark K, et al. (2013) Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. Acs Chemical Biology. 8: 812-22
Mechaly A, McCluskey AJ, Collier RJ. (2012) Changing the receptor specificity of anthrax toxin. Mbio. 3
Rodnin MV, Kyrychenko A, Kienker PK, et al. (2012) Comparison of Various Methods for Determining Functional Activity of the Diphtheria Toxin T-Domain Biophysical Journal. 102: 244a-245a
Rodnin MV, Kyrychenko A, Kienker P, et al. (2011) Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain. Biophysical Journal. 101: L41-3
Fischer A, Holden MA, Pentelute BL, et al. (2011) Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers. Proceedings of the National Academy of Sciences of the United States of America. 108: 16577-81
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