Jacqueline K. Lekostaj, Ph.D.

2008 Tumor Biology Georgetown University, Washington, DC 
Parasitology, Biochemistry, Molecular Biology
"Jacqueline Lekostaj"


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Paul D. Roepe grad student 2008 Georgetown
 (Molecular analysis of membrane transporters implicated in drug resistance.)
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Pleeter P, Lekostaj JK, Roepe PD. (2010) Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue. Molecular and Biochemical Parasitology. 173: 158-61
Lekostaj JK, Natarajan JK, Paguio MF, et al. (2008) Photoaffinity labeling of the Plasmodium falciparum chloroquine resistance transporter with a novel perfluorophenylazido chloroquine. Biochemistry. 47: 10394-406
Lekostaj JK, Amoah LE, Roepe PD. (2008) A single S1034C mutation confers altered drug sensitivity to PfMDR1 ATPase activity that is characteristic of the 7G8 isoform. Molecular and Biochemical Parasitology. 157: 107-11
Amoah LE, Lekostaj JK, Roepe PD. (2007) Heterologous expression and ATPase activity of mutant versus wild type PfMDR1 protein. Biochemistry. 46: 6060-73
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