John N. Alumasa, Ph.D.

Affiliations: 
2010 Chemistry Georgetown University, Washington, DC 
Area:
Parasitology, Biochemistry, Molecular Biology
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"John Alumasa"

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Paul D. Roepe grad student 2010 Georgetown
 (New insights on the structure-function principles & design of quinoline antimalarial drugs.)
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Publications

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Alumasa JN, Keiler KC. (2015) Clicking on trans-translation drug targets. Frontiers in Microbiology. 6: 498
El-Mowafi SA, Sineva E, Alumasa JN, et al. (2015) Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay. Antimicrobial Agents and Chemotherapy. 59: 193-205
El-Mowafi SA, Alumasa JN, Ades SE, et al. (2014) Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway. Antimicrobial Agents and Chemotherapy. 58: 5500-9
Keiler KC, Alumasa JN. (2013) The potential of trans-translation inhibitors as antibiotics. Future Microbiology. 8: 1235-7
Gorka AP, Alumasa JN, Sherlach KS, et al. (2013) Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth. Antimicrobial Agents and Chemotherapy. 57: 356-64
McGillivray SM, Tran DN, Ramadoss NS, et al. (2012) Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics. Antimicrobial Agents and Chemotherapy. 56: 1854-61
Pan E, Gorka AP, Alumasa JN, et al. (2011) Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. Journal of Natural Products. 74: 2174-80
Alumasa JN, Gorka AP, Casabianca LB, et al. (2011) The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. Journal of Inorganic Biochemistry. 105: 467-75
Iwaniuk DP, Whetmore ED, Rosa N, et al. (2009) Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain. Bioorganic & Medicinal Chemistry. 17: 6560-6
Hou Y, Cao S, Brodie PJ, et al. (2009) Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest. Bioorganic & Medicinal Chemistry. 17: 2871-6
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