Mylisa R. Pilione, Ph.D.

Affiliations: 
2005 Pennsylvania State University, State College, PA, United States 
Area:
Immunology, Virology, Microbiology
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"Mylisa Pilione"

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Eric T. Harvill grad student 2005 Penn State
 (Interactions of Bordetella bronchiseptica virulence determinants and host immune factors that mediate persistent infection of the lower respiratory tract.)
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Publications

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Thakar J, Pilione M, Kirimanjeswara G, et al. (2007) Modeling systems-level regulation of host immune responses. Plos Computational Biology. 3: e109
Mann P, Goebel E, Barbarich J, et al. (2007) Use of a genetically defined double mutant strain of Bordetella bronchiseptica lacking adenylate cyclase and type III secretion as a live vaccine. Infection and Immunity. 75: 3665-72
Pilione MR, Agosto LM, Kennett MJ, et al. (2006) CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection. Cellular Microbiology. 8: 758-68
Pilione MR, Harvill ET. (2006) The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance. Infection and Immunity. 74: 1043-9
Kirimanjeswara GS, Mann PB, Pilione M, et al. (2005) The complex mechanism of antibody-mediated clearance of Bordetella from the lungs requires TLR4. Journal of Immunology (Baltimore, Md. : 1950). 175: 7504-11
Skinner JA, Pilione MR, Shen H, et al. (2005) Bordetella type III secretion modulates dendritic cell migration resulting in immunosuppression and bacterial persistence. Journal of Immunology (Baltimore, Md. : 1950). 175: 4647-52
Pilione MR, Pishko EJ, Preston A, et al. (2004) pagP is required for resistance to antibody-mediated complement lysis during Bordetella bronchiseptica respiratory infection. Infection and Immunity. 72: 2837-42
Pishko EJ, Kirimanjeswara GS, Pilione MR, et al. (2004) Antibody-mediated bacterial clearance from the lower respiratory tract of mice requires complement component C3. European Journal of Immunology. 34: 184-93
Melkun E, Pilione M, Paulson RF. (2002) A naturally occurring point substitution in Cdc25A, and not Fv2/Stk, is associated with altered cell-cycle status of early erythroid progenitor cells. Blood. 100: 3804-11
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