Ralph M. Steinman, M.D.

Rockefeller University, New York, NY, United States 
"Ralph Steinman"

(1943 - 2011)
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity.


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Elizabeth D. Hay grad student 1968 Harvard Medical School (Cell Biology Tree)
Zanvil A. Cohn post-doc 1970-1972 Rockefeller (Cell Biology Tree)
René Dubos post-doc 1970-1972 Rockefeller
James G. Hirsch post-doc 1970-1972 Rockefeller


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Jeremy Luban research assistant Rockefeller (Microtree)
Gwendalyn Randolph grad student (Cell Biology Tree)
Wesley C. Van Voorhis grad student Rockerfeller University (Microtree)
Davorka Messmer grad student 2000 Rockefeller
Dennis J. Sawchuk grad student 2002 Rockefeller
Ira Mellman post-doc Rockefeller (Cell Biology Tree)
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Randolph GJ, Beaulieu S, Lebecque S, et al. (2017) Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483. Journal of Immunology (Baltimore, Md. : 1950). 198: 4191-4194
Anandasabapathy N, Feder R, Mollah S, et al. (2014) Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of Experimental Medicine. 211: 1875-91
Flacher V, Tripp CH, Mairhofer DG, et al. (2014) Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. Embo Molecular Medicine. 6: 1191-204
Pantel A, Teixeira A, Haddad E, et al. (2014) Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. Plos Biology. 12: e1001759
Mollah SA, Dobrin JS, Feder RE, et al. (2014) Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. The Journal of Investigative Dermatology. 134: 1265-75
Ruane D, Brane L, Reis BS, et al. (2013) Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. The Journal of Experimental Medicine. 210: 1871-88
Matos I, Mizenina O, Lubkin A, et al. (2013) Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity. Plos One. 8: e67453
Coconi-Linares N, Ortega-Dávila E, López-González M, et al. (2013) Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice. Vaccine. 31: 2366-71
Barbuto S, Idoyaga J, Vila-Perelló M, et al. (2013) Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells. Nature Chemical Biology. 9: 250-6
Idoyaga J, Fiorese C, Zbytnuik L, et al. (2013) Specialized role of migratory dendritic cells in peripheral tolerance induction. The Journal of Clinical Investigation. 123: 844-54
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