Ralph M. Steinman, M.D.
|Rockefeller University, New York, NY, United States|
(1943 - 2011)
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann
for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman
for his discovery of the dendritic cell and its role in adaptive immunity.
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|Randolph GJ, Beaulieu S, Lebecque S, et al. (2017) Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483. Journal of Immunology (Baltimore, Md. : 1950). 198: 4191-4194|
|Anandasabapathy N, Feder R, Mollah S, et al. (2014) Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of Experimental Medicine. 211: 1875-91|
|Flacher V, Tripp CH, Mairhofer DG, et al. (2014) Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. Embo Molecular Medicine. 6: 1191-204|
|Pantel A, Teixeira A, Haddad E, et al. (2014) Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. Plos Biology. 12: e1001759|
|Mollah SA, Dobrin JS, Feder RE, et al. (2014) Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. The Journal of Investigative Dermatology. 134: 1265-75|
|Ruane D, Brane L, Reis BS, et al. (2013) Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. The Journal of Experimental Medicine. 210: 1871-88|
|Matos I, Mizenina O, Lubkin A, et al. (2013) Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity. Plos One. 8: e67453|
|Coconi-Linares N, Ortega-DÃ¡vila E, LÃ³pez-GonzÃ¡lez M, et al. (2013) Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice. Vaccine. 31: 2366-71|
|Barbuto S, Idoyaga J, Vila-PerellÃ³ M, et al. (2013) Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells. Nature Chemical Biology. 9: 250-6|
|Idoyaga J, Fiorese C, Zbytnuik L, et al. (2013) Specialized role of migratory dendritic cells in peripheral tolerance induction. The Journal of Clinical Investigation. 123: 844-54|