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Ralph M. Steinman, M.D.

Rockefeller University, New York, NY, United States 
"Ralph Steinman"

(1943 - 2011)
The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity.

Cross-listing: ImmunoTree


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Elizabeth D. Hay grad student 1968 Harvard Medical School (Cell Biology Tree)
Zanvil A. Cohn post-doc 1970-1972 Rockefeller (Cell Biology Tree)
René Dubos post-doc 1970-1972 Rockefeller
James G. Hirsch post-doc 1970-1972 Rockefeller


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Jeremy Luban research assistant Rockefeller (Microtree)
Gwendalyn Randolph grad student (Cell Biology Tree)
Wesley C. Van Voorhis grad student Rockerfeller University (Microtree)
Davorka Messmer grad student 2000 Rockefeller
Dennis J. Sawchuk grad student 2002 Rockefeller
Ira Mellman post-doc Rockefeller (Cell Biology Tree)
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Zaidi N, Quezada SA, Kuroiwa JMY, et al. (2019) Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4 effector T cell infiltration into murine pancreatic tumors. Annals of the New York Academy of Sciences
Randolph GJ, Beaulieu S, Lebecque S, et al. (2017) Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483. Journal of Immunology (Baltimore, Md. : 1950). 198: 4191-4194
Ngu LN, Nji NN, Ambada GE, et al. (2017) In vivo targeting of protein antigens to dendritic cells using anti-DEC-205 single chain antibody improves HIV Gag specific CD4(+) T cell responses protecting from airway challenge with recombinant vaccinia-gag virus. Immunity, Inflammation and Disease
Sela U, Park CG, Park A, et al. (2016) Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses. Plos One. 11: e0146412
Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, et al. (2015) ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis. Plos One. 10: e0124828
Anandasabapathy N, Feder R, Mollah S, et al. (2014) Classical Flt3L-dependent dendritic cells control immunity to protein vaccine. The Journal of Experimental Medicine. 211: 1875-91
Flacher V, Tripp CH, Mairhofer DG, et al. (2014) Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. Embo Molecular Medicine. 6: 1191-204
Pantel A, Teixeira A, Haddad E, et al. (2014) Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation. Plos Biology. 12: e1001759
Mollah SA, Dobrin JS, Feder RE, et al. (2014) Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. The Journal of Investigative Dermatology. 134: 1265-75
Mollah SA, Dobrin JS, Feder RE, et al. (2014) Correction to: “Flt3L Dependence Helps Define an Uncharacterized Subset of Murine Cutaneous Dendritic Cells” Journal of Investigative Dermatology. 134: 2850-2851
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