Lijun Sun
Affiliations: | University of Texas Southwestern Medical Center, Dallas, TX, United States |
Area:
Innate ImmunityGoogle:
"Lijun Sun"
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Publications
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| Tan X, Sun L, Chen J, et al. (2018) Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids. Annual Review of Microbiology. 72: 447-478 |
| Wang H, Hu S, Chen X, et al. (2017) cGAS is essential for the antitumor effect of immune checkpoint blockade. Proceedings of the National Academy of Sciences of the United States of America |
| Chen Q, Sun L, Chen ZJ. (2016) Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing. Nature Immunology. 17: 1142-1149 |
| Li XD, Wu J, Gao D, et al. (2013) Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science (New York, N.Y.). 341: 1390-4 |
| Liu S, Chen J, Cai X, et al. (2013) MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades. Elife. 2: e00785 |
| Zhang X, Shi H, Wu J, et al. (2013) Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Molecular Cell. 51: 226-35 |
| Sun L, Wu J, Du F, et al. (2013) Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway Science. 339: 786-791 |
| Wu J, Sun L, Chen X, et al. (2013) Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science (New York, N.Y.). 339: 826-30 |
| Hou F, Sun L, Zheng H, et al. (2011) MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell. 146: 448-61 |
| Zeng W, Sun L, Jiang X, et al. (2010) Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell. 141: 315-30 |