Javier E. Irazoqui
Affiliations: | 2008-2017 | Massachusetts General Hospital | Harvard Medical School, Boston, MA, United States |
| 2017- | Microbiology and Physiological Systems | University of Massachussetts Medical School, Worcester, MA, United States |
Area:
Host-microbe interactions, caenorhabditis elegans, staphylococcus aureus, bacterial pathogenesisGoogle:
"Javier Elbio Irazoqui"Parents
Sign in to add mentor| Daniel Lew | grad student | 2003 | Duke (Cell Biology Tree) | |
| (Scaffold-mediated symmetry breaking by Cdc42p.) | ||||
| Fred M. Ausubel | post-doc | 2003-2009 | Harvard (Chemistry Tree) | |
Children
Sign in to add trainee| Ana-Maria Alves | research assistant | Harvard Medical School | |
| Joseph Moreau | research assistant | UMass Med School | |
| Michael S Moubarek | research assistant | 2015-2017 | Massachuestts General Hospital / UMass Med School (Chemistry Tree) |
| Debanjan Goswamy | grad student | University of Massachusetts Medical School | |
| Lucy Eunjun Lee | grad student | Harvard College | |
| Suleiman Hamarneh | post-doc | Harvard Medical School | |
| Sid Ahmed Labed | post-doc | Harvard Medical School | |
| Mehran Najibi | post-doc | Harvard Medical School | |
| Khursheed Wani | post-doc | University of Massachusetts Medical School | |
| Amanda C. Wollenberg | post-doc | Harvard Medical School (Plant Biology Tree) | |
| Orane Visvikis | post-doc | 2010-2014 | Harvard Medical School |
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Publications
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| Honwad HH, Najibi M, Koscso B, et al. (2024) TFEB-Mediated Pro-inflammatory Response in Murine Macrophages Induced by Acute Alpha7 Nicotinic Receptor Activation. Biorxiv : the Preprint Server For Biology |
| Colino-Lage H, Guerrero-Gómez D, Gómez-Orte E, et al. (2024) Regulation of Caenorhabditis elegans HLH-30 subcellular localization dynamics: Evidence for a redox-dependent mechanism. Free Radical Biology & Medicine |
| Kingsley SF, Seo Y, Wood A, et al. (2024) Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens. Scientific Reports. 14: 13177 |
| Gonzalez X, Irazoqui JE. (2024) Distinct members of the Caenorhabditis elegans CeMbio reference microbiota exert cryptic virulence that is masked by host defense. Molecular Microbiology |
| Gonzalez X, Irazoqui JE. (2023) Distinct members of the CeMbio reference microbiota exert cryptic virulence and infection protection. Biorxiv : the Preprint Server For Biology |
| Goswamy D, Gonzalez X, Labed SA, et al. (2023) orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB. Frontiers in Immunology. 14: 1094145 |
| Wani KA, Goswamy D, Taubert S, et al. (2021) NHR-49/PPAR-α and HLH-30/TFEB cooperate for host defense via a flavin-containing monooxygenase. Elife. 10 |
| Najibi M, Honwad HH, Moreau JA, et al. (2021) A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS. Autophagy. 1-18 |
| Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382 |
| Goswamy D, Irazoqui JE. (2020) A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans. Current Opinion in Immunology. 68: 9-20 |