Eugene Goldwasser, Ph.D.

Affiliations: 
1952-2002 Biochemistry University of Chicago, Chicago, IL 
Area:
Erythropoietin
Website:
https://news.uchicago.edu/article/2010/12/22/eugene-goldwasser-biochemist-behind-blockbuster-anemia-drug-1922-2010
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"Eugene Goldwasser"
Bio:

1922-2010. Undergraduate study and Ph.D. in biochemistry at University of Chicago. Studied anthrax at Fort Detrick briefly and then returned to University of Chicago, where he spent his career. Best known for discovering erythropoietin in 1977 after 15 years of research. Retired in 2002.
http://www.nytimes.com/2010/12/21/health/21goldwasser.html
http://en.wikipedia.org/wiki/Eugene_Goldwasser
http://www.jbc.org/content/190/1/75.long

Parents

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Frank W. Putnam grad student 1950 Chicago (Chemistry Tree)
 (Physico-chemical studies of bacteriophage.)
Herman M. Kalckar post-doc 1950-1952 Københavns Universitet (Chemistry Tree)

Children

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David Schlessinger research assistant Chicago
Robert LeRoy Heinrikson grad student 1963 Chicago (Chemistry Tree)
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Publications

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Gupta M, Mungai PT, Goldwasser E. (2000) A new transacting factor that modulates hypoxia-induced expression of the erythropoietin gene. Blood. 96: 491-7
Kung C, Fan L, Goldwasser E. (2000) The role of tyrosine 15 in erythropoietin action. Archives of Biochemistry and Biophysics. 379: 85-9
Jacobson LO, Goldwasser E, Fried W, et al. (2000) Role of the kidney in erythropoiesis. 1957. Journal of the American Society of Nephrology : Jasn. 11: 589-90; discussion 5
Mujais SK, Beru N, Pullman TN, et al. (1999) Erythropoietin is produced by tubular cells of the rat kidney. Cell Biochemistry and Biophysics. 30: 153-66
Chandel NS, Maltepe E, Goldwasser E, et al. (1998) Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proceedings of the National Academy of Sciences of the United States of America. 95: 11715-20
Stopka T, Zivny JH, Goldwasser E, et al. (1998) Guinea pig serum erythropoietin (EPO) selectively stimulates guinea pig erythroid progenitors: human or mouse erythroid progenitors do not form erythroid burst-forming unit colonies in response to guinea pig serum EPO. Experimental Hematology. 26: 910-4
Ang S, Necas E, Sykora V, et al. (1998) Erythropoietin receptor / erythropoietin recognition in octodon degus, guinea pig, mouse and man Experimental Hematology. 26: 725
Svensson EC, Black HB, Dugger DL, et al. (1997) Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector. Human Gene Therapy. 8: 1797-806
Haidar MA, Loya F, Yang Y, et al. (1997) Electron microscopic localization of lacZ expression in the proximal convoluted tubular cells of the kidney in transgenic mice carrying chimeric erythropoietin/lacZ gene constructs. Journal of Structural Biology. 118: 220-5
Kung CK, Goldwasser E. (1997) A probable conformational difference between recombinant and urinary erythropoietins. Proteins. 28: 94-8
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