Susan Gottesman

Laboratory of Molecular Biology National Institutes of Health, Bethesda, MD 
Bacteriophage, Proteolysis, small RNAs
"Susan Gottesman"

Radcliffe College undergraduate, then Ph.D. from Harvard in Microbiology and Molecular Genetics, followed by a post-doc at NIH. She is known for the discovery of the 2-component ATP-dependent protease known as CIpAP.


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Boris Magasanik research assistant MIT (Cell Biology Tree)
 (kinetics of induction of lac operon)
James D. Watson research assistant Harvard (Chemistry Tree)
Jonathan R. Beckwith grad student Harvard Medical School (Chemistry Tree)
 (arac operon)
Max E. Gottesman post-doc NIH


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Julie A Brill research assistant 1985-1986 Lab of Molecular Biology (FlyTree)
C. Brandon Ogbunu research assistant 2000-2002 (Evolution Tree)
Laurence van Melderen post-doc NIH - NIDDK (Microtree)
Valerie A. de Crecy-Lagard post-doc 1991-1992 NIH
Kumari Kavita post-doc 2014-2020 National Institutes of Health, Bethesda (Microtree)
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Majdalani N, Chattopadhyay M, Keller C, et al. (2023) Lack of polyamines leads to cotranslational degradation of the general stress factor RpoS in Escherichia coli. The Journal of Biological Chemistry. 299: 104943
Morita T, Majdalani N, Miura MC, et al. (2022) Identification of Attenuators of Transcriptional Termination: Implications for RNA Regulation in Escherichia coli. Mbio. e0237122
Kavita K, Zhang A, Tai CH, et al. (2022) Multiple in vivo roles for the C-terminal domain of the RNA chaperone Hfq. Nucleic Acids Research. 50: 1718-1733
Chen J, To L, de Mets F, et al. (2021) A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in . Proceedings of the National Academy of Sciences of the United States of America. 118
Wall EA, Majdalani N, Gottesman S. (2020) IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein. Plos Genetics. 16: e1008610
Hör J, Matera G, Vogel J, et al. (2020) Trans-Acting Small RNAs and Their Effects on Gene Expression in and . Ecosal Plus. 9
Thomason MK, Voichek M, Dar D, et al. (2019) A 5' UTR-Derived sRNA Regulates RhlR-Dependent Quorum Sensing in Pseudomonas aeruginosa. Mbio. 10
Chen J, Morita T, Gottesman S. (2019) Regulation of Transcription Termination of Small RNAs and by Small RNAs: Molecular Mechanisms and Biological Functions. Frontiers in Cellular and Infection Microbiology. 9: 201
Gottesman S. (2019) Trouble is coming: Signaling pathways that regulate general stress responses in bacteria. The Journal of Biological Chemistry
Dorich V, Brugger C, Tripathi A, et al. (2019) Structural basis for inhibition of a response regulator of σ stability by a ClpXP antiadaptor. Genes & Development
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