Andrew Flyak

Affiliations: 
2012-2016 Microbiology and Immunology Vanderbilt University School of Medicine, Nashville, TN, United States 
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"Andrew Flyak"
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Ogega CO, Skinner NE, Schoenle MV, et al. (2024) Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance. Immunity
Frumento N, Sinnis-Bourozikas A, Paul HT, et al. (2023) Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection. Immunity
Bozhanova NG, Flyak AI, Brown BP, et al. (2022) Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nature Communications. 13: 3178
Frumento N, Figueroa A, Wang T, et al. (2022) Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency. The Journal of Clinical Investigation
Ogega CO, Skinner NE, Flyak AI, et al. (2022) B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. Plos Pathogens. 18: e1010179
Weber T, Potthoff J, Bizu S, et al. (2021) Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity
Muecksch F, Weisblum Y, Barnes CO, et al. (2021) Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations. Immunity
Murin CD, Gilchuk P, Ilinykh PA, et al. (2021) Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Reports. 35: 108984
Muecksch F, Weisblum Y, Barnes CO, et al. (2021) Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies. Biorxiv : the Preprint Server For Biology
Flyak AI, Ruiz SE, Salas J, et al. (2020) Author response: An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein Elife
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