Andrew Flyak
Affiliations: | 2012-2016 | Microbiology and Immunology | Vanderbilt University School of Medicine, Nashville, TN, United States |
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"Andrew Flyak"Parents
Sign in to add mentorJames Earl Crowe, Jr. | grad student | 2012-2016 | Vanderbilt Medical School |
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Publications
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Ogega CO, Skinner NE, Schoenle MV, et al. (2024) Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance. Immunity |
Frumento N, Sinnis-Bourozikas A, Paul HT, et al. (2023) Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection. Immunity |
Bozhanova NG, Flyak AI, Brown BP, et al. (2022) Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nature Communications. 13: 3178 |
Frumento N, Figueroa A, Wang T, et al. (2022) Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency. The Journal of Clinical Investigation |
Ogega CO, Skinner NE, Flyak AI, et al. (2022) B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. Plos Pathogens. 18: e1010179 |
Weber T, Potthoff J, Bizu S, et al. (2021) Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity |
Muecksch F, Weisblum Y, Barnes CO, et al. (2021) Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations. Immunity |
Murin CD, Gilchuk P, Ilinykh PA, et al. (2021) Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Reports. 35: 108984 |
Muecksch F, Weisblum Y, Barnes CO, et al. (2021) Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies. Biorxiv : the Preprint Server For Biology |
Flyak AI, Ruiz SE, Salas J, et al. (2020) Author response: An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein Elife |