Phillip W. Berman

Biomolecular Engineering University of California, Santa Cruz, Santa Cruz, CA, United States 
Drug development, vaccines, AIDS, monoclonal antibody therapeutics, immunology, molecular cell/biology, recombinant protein production
"Phillip Wayne Berman"

Cross-listing: Chemistry Tree


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Henry A. Harbury grad student 1977 Dartmouth Medical School (Chemistry Tree)
 (Immunochemistry of horse cytochrome c̲ : identification of antigenic determinants through studies of reconstituted and hybrid preparations)
Steve F. Heinemann post-doc 1977-1981 Salk Institute (Neurotree)
Herbert W. Boyer post-doc 1981-1982 UCSF


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Javier F. Morales grad student 2014 UC Santa Cruz (Chemistry Tree)
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Li SW, Wright M, Healey JF, et al. (2020) Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens. Plos One. 15: e0233866
Hutchinson JM, Mesa KA, Alexander DL, et al. (2019) Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies. Frontiers in Immunology. 10: 1021
Li S, Yu B, Byrne G, et al. (2019) Identification and CRISPR/Cas9 Knockout of the Endogenous C1s Protease in CHO Cells Eliminates Aberrant Proteolysis of Recombinantly Expressed Proteins. Biotechnology and Bioengineering
Mesa KA, Yu B, Wrin T, et al. (2019) Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens. Plos One. 14: e0213409
O'Rourke SM, Yu B, Morales JF, et al. (2018) Production of a recombinant monoclonal antibody to Herpes Simplex Virus glycoprotein D for immunoaffinity purification of tagged proteins. Journal of Immunological Methods
Doran RC, Yu B, Wright M, et al. (2018) Development of a Stable MGAT1 CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies. Frontiers in Immunology. 9: 2313
Byrne G, O'Rourke SM, Alexander DL, et al. (2018) CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation. Plos Biology. 16: e2005817
O'Rourke SM, Byrne G, Tatsuno G, et al. (2018) Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production. Plos One. 13: e0197656
Doran RC, Tatsuno GP, O'Rourke SM, et al. (2018) Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies. Plos One. 13: e0196370
Yates NL, deCamp AC, Korber BT, et al. (2018) HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees. Journal of Virology
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