Jay P. Farrell, Ph.D.

Affiliations: 
Pathobiology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Leishmania, Immunology
Website:
http://www.med.upenn.edu/apps/faculty/index.php/g20000320/p4382004
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"Jay Farrell"
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Publications

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Padigel UM, Farrell JP. (2005) Control of infection with Leishmania major in susceptible BALB/c mice lacking the common gamma-chain for FcR is associated with reduced production of IL-10 and TGF-beta by parasitized cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 6340-5
Padigel UM, Kim N, Choi Y, et al. (2003) TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 5437-41
Padigel UM, Alexander J, Farrell JP. (2003) The role of interleukin-10 in susceptibility of BALB/c mice to infection with Leishmania mexicana and Leishmania amazonensis. Journal of Immunology (Baltimore, Md. : 1950). 171: 3705-10
Padigel UM, Farrell JP. (2003) CD40-CD40 ligand costimulation is not required for initiation and maintenance of a Th1-type response to Leishmania major infection. Infection and Immunity. 71: 1389-95
Li J, Padigel UM, Scott P, et al. (2002) Combined treatment with interleukin-12 and indomethacin promotes increased resistance in BALB/c mice with established Leishmania major infections. Infection and Immunity. 70: 5715-20
Compton HL, Farrell JP. (2002) CD28 costimulation and parasite dose combine to influence the susceptibility of BALB/c mice to infection with Leishmania major. Journal of Immunology (Baltimore, Md. : 1950). 168: 1302-8
Padigel UM, Perrin PJ, Farrell JP. (2001) The development of a Th1-type response and resistance to Leishmania major infection in the absence of CD40-CD40L costimulation. Journal of Immunology (Baltimore, Md. : 1950). 167: 5874-9
Murphy ML, Wille U, Villegas EN, et al. (2001) IL-10 mediates susceptibility to Leishmania donovani infection. European Journal of Immunology. 31: 2848-56
Li J, Hunter CA, Farrell JP. (1999) Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production. Journal of Immunology (Baltimore, Md. : 1950). 162: 974-9
Scott P, Farrell JP. (1998) Experimental cutaneous leishmaniasis: induction and regulation of T cells following infection of mice with Leishmania major. Chemical Immunology. 70: 60-80
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