Jules A. Hoffmann

Université de Strasbourg 
"Jules A. Hoffmann"

The Nobel Prize in Physiology or Medicine 2011 was divided, one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity.

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Majzoub K, Hafirassou ML, Meignin C, et al. (2014) RACK1 controls IRES-mediated translation of viruses. Cell. 159: 1086-95
Hoffmann J, Tárnoki A, Tárnoki D. (2014) Q&A: Jules Hoffmann. Fighting fit. Nature. 514: S5
Chtarbanova S, Lamiable O, Lee KZ, et al. (2014) Drosophila C virus systemic infection leads to intestinal obstruction. Journal of Virology. 88: 14057-69
Tartey S, Matsushita K, Vandenbon A, et al. (2014) Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. The Embo Journal. 33: 2332-48
Goto A, Fukuyama H, Imler JL, et al. (2014) The chromatin regulator DMAP1 modulates activity of the nuclear factor κB (NF-κB) transcription factor Relish in the Drosophila innate immune response Journal of Biological Chemistry. 289: 20470-20476
Fukuyama H, Verdier Y, Guan Y, et al. (2013) Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Proceedings of the National Academy of Sciences of the United States of America. 110: 10717-22
Bonnay F, Cohen-Berros E, Hoffmann M, et al. (2013) big bang gene modulates gut immune tolerance in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 2957-62
Kemp C, Mueller S, Goto A, et al. (2013) Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila. Journal of Immunology (Baltimore, Md. : 1950). 190: 650-8
Liu X, Sano T, Guan Y, et al. (2012) Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif Plos One. 7
Lemaitre B, Nicolas E, Michaut L, et al. (2012) Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983. Journal of Immunology (Baltimore, Md. : 1950). 188: 5210-20
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