Jakob Helmuth von Moltke

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
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"Jakob von Moltke"

Parents

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Russell E. Vance grad student 2012 UC Berkeley
 (Suicidal Cells and Lipid Storms Mechanisms and Consequences of Cytokine-independent Inflammasome Activation.)
Richard M. Locksley post-doc UCSF (Microtree)
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Publications

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Kasal DN, Warner L, Bryant A, et al. (2024) Systemic Immune Modulation by Gastrointestinal Nematodes. Annual Review of Immunology
Nadjsombati MS, Niepoth N, Webeck LM, et al. (2023) Genetic mapping reveals OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science Immunology. 8: eade5019
Billipp TE, Fung C, Webeck LM, et al. (2023) Tuft cell-derived acetylcholine regulates epithelial fluid secretion. Biorxiv : the Preprint Server For Biology
McDaniel MM, Lara HI, von Moltke J. (2023) Initiation of type 2 immunity at barrier surfaces. Mucosal Immunology
Barr J, Gentile ME, Lee S, et al. (2022) Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair. Elife. 11
Karo-Atar D, Ouladan S, Javkar T, et al. (2022) Helminth-induced reprogramming of the stem cell compartment inhibits type 2 immunity. The Journal of Experimental Medicine. 219
Zhao M, Ren K, Xiong X, et al. (2022) Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. Immunity. 55: 623-638.e5
O'Leary CE, Sbierski-Kind J, Kotas ME, et al. (2022) Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Science Immunology. 7: eabj1080
Oyesola OO, Shanahan MT, Kanke M, et al. (2021) PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection. The Journal of Experimental Medicine. 218
Billipp TE, Nadjsombati MS, von Moltke J. (2020) Tuning tuft cells: new ligands and effector functions reveal tissue-specific function. Current Opinion in Immunology. 68: 98-106
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