Jakob Helmuth von Moltke

Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
"Jakob von Moltke"


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Russell E. Vance grad student 2012 UC Berkeley
 (Suicidal Cells and Lipid Storms Mechanisms and Consequences of Cytokine-independent Inflammasome Activation.)
Richard M. Locksley post-doc UCSF (Microtree)
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Nadjsombati MS, Niepoth N, Webeck LM, et al. (2023) Genetic mapping reveals OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science Immunology. 8: eade5019
Billipp TE, Fung C, Webeck LM, et al. (2023) Tuft cell-derived acetylcholine regulates epithelial fluid secretion. Biorxiv : the Preprint Server For Biology
McDaniel MM, Lara HI, von Moltke J. (2023) Initiation of type 2 immunity at barrier surfaces. Mucosal Immunology
Barr J, Gentile ME, Lee S, et al. (2022) Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair. Elife. 11
Karo-Atar D, Ouladan S, Javkar T, et al. (2022) Helminth-induced reprogramming of the stem cell compartment inhibits type 2 immunity. The Journal of Experimental Medicine. 219
Zhao M, Ren K, Xiong X, et al. (2022) Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. Immunity. 55: 623-638.e5
O'Leary CE, Sbierski-Kind J, Kotas ME, et al. (2022) Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Science Immunology. 7: eabj1080
Oyesola OO, Shanahan MT, Kanke M, et al. (2021) PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection. The Journal of Experimental Medicine. 218
Billipp TE, Nadjsombati MS, von Moltke J. (2020) Tuning tuft cells: new ligands and effector functions reveal tissue-specific function. Current Opinion in Immunology. 68: 98-106
McGinty JW, Ting HA, Billipp TE, et al. (2020) Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity
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