| Year |
Citation |
Score |
| 2023 |
Xia Y, Cheng X, Nilsson T, Zhang M, Zhao G, Inuzuka T, Teng Y, Li Y, Anderson DE, Holdorf M, Liang TJ. Nucleolin binds to and regulates transcription of hepatitis B virus covalently closed circular DNA minichromosome. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306390120. PMID 38015841 DOI: 10.1073/pnas.2306390120 |
0.318 |
|
| 2023 |
Liang TJ, Law JLM, Pietschmann T, Ray SC, Bukh J, Bull R, Chung RT, Tyrrell DL, Houghton M, Rice CM. Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 77: S257-S261. PMID 37579208 DOI: 10.1093/cid/ciad336 |
0.381 |
|
| 2023 |
Rid A, Feld JJ, Liang TJ, Weijer C. Ethics of Controlled Human Infection Studies With Hepatitis C Virus. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 77: S216-S223. PMID 37579202 DOI: 10.1093/cid/ciad382 |
0.428 |
|
| 2023 |
Chida T, Ishida Y, Morioka S, Sugahara G, Han C, Lam B, Yamasaki C, Sugahara R, Li M, Tanaka Y, Liang TJ, Tateno C, Saito T. Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response. Jci Insight. 8. PMID 37154158 DOI: 10.1172/jci.insight.162404 |
0.409 |
|
| 2022 |
Park SB, Irvin P, Hu Z, Khan M, Hu X, Zeng Q, Chen C, Xu M, Leek M, Zang R, Case JB, Zheng W, Ding S, Liang TJ. Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors. Mbio. e0323821. PMID 35012356 DOI: 10.1128/mbio.03238-21 |
0.332 |
|
| 2021 |
Uchida T, Park SB, Inuzuka T, Zhang M, Allen JN, Chayama K, Liang TJ. Genetically edited hepatic cells expressing the NTCP-S267F variant are resistant to hepatitis B virus infection. Molecular Therapy. Methods & Clinical Development. 23: 597-605. PMID 34853804 DOI: 10.1016/j.omtm.2021.11.002 |
0.34 |
|
| 2021 |
Gara N, Tana MM, Kattapuram M, Auh S, Sullivan L, Fryzek N, Walter M, Umarova R, Zhao X, Cloherty G, Doo E, Heller T, Liang TJ, Ghany MG. Prospective Study of Withdrawal of Antiviral therapy in Patients with Chronic Hepatitis B after Prolonged Virological Response. Hepatology Communications. PMID 34558806 DOI: 10.1002/hep4.1761 |
0.301 |
|
| 2021 |
Liang TJ, Feld JJ, Cox AL, Rice CM. Controlled Human Infection Model - Fast Track to HCV Vaccine? The New England Journal of Medicine. 385: 1235-1240. PMID 34551234 DOI: 10.1056/NEJMsb2109093 |
0.306 |
|
| 2021 |
Zhang M, Zhang Z, Imamura M, Osawa M, Teraoka Y, Piotrowski J, Ishida Y, Sozzi V, Revill PA, Saito T, Chayama K, Liang TJ. Infection courses, virological features and IFN-α responses of HBV genotypes in cell culture and animal models. Journal of Hepatology. PMID 34363922 DOI: 10.1016/j.jhep.2021.07.030 |
0.364 |
|
| 2021 |
Rolt A, Talley DC, Park SB, Hu Z, Dulcey A, Ma C, Irvin P, Leek M, Wang AQ, Stachulski AV, Xu X, Southall N, Ferrer M, Liang TJ, Marugan JJ. Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly. Journal of Medicinal Chemistry. PMID 34184537 DOI: 10.1021/acs.jmedchem.1c00696 |
0.801 |
|
| 2021 |
Page K, Melia MT, Veenhuis RT, Winter M, Rousseau KE, Massaccesi G, Osburn WO, Forman M, Thomas E, Thornton K, Wagner K, Vassilev V, Lin L, Lum PJ, Giudice LC, ... ... Liang TJ, et al. Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection. The New England Journal of Medicine. 384: 541-549. PMID 33567193 DOI: 10.1056/NEJMoa2023345 |
0.4 |
|
| 2020 |
Ma CD, Imamura M, Talley DC, Rolt A, Xu X, Wang AQ, Le D, Uchida T, Osawa M, Teraoka Y, Li K, Hu X, Park SB, Chalasani N, Irvin PH, ... ... Liang TJ, et al. Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion. Nature Microbiology. PMID 32868923 DOI: 10.1038/S41564-020-0781-2 |
0.815 |
|
| 2020 |
Mouzannar K, Liang TJ. Hepatitis B virus - recent therapeutic advances and challenges to cure. Journal of Hepatology. PMID 32682539 DOI: 10.1016/J.Jhep.2020.04.015 |
0.456 |
|
| 2020 |
Murayama A, Yamada N, Osaki Y, Shiina M, Aly HH, Iwamoto M, Tsukuda S, Watashi K, Matsuda M, Suzuki R, Tanaka T, Moriishi K, Suzuki T, Nishitsuji H, Sugiyama M, ... ... Liang TJ, et al. N-terminal PreS1 Sequence Regulates Efficient Infection of Cell Culture-generated Hepatitis B Virus. Hepatology (Baltimore, Md.). PMID 32446278 DOI: 10.1002/Hep.31308 |
0.442 |
|
| 2020 |
Hu Z, Rolt A, Hu X, Ma CD, Le DJ, Park SB, Houghton M, Southall N, Anderson DE, Talley DC, Lloyd JR, Marugan JC, Liang TJ. Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1. Cell Chemical Biology. PMID 32386595 DOI: 10.1016/J.Chembiol.2020.04.006 |
0.803 |
|
| 2020 |
Ding S, Liang TJ. Is SARS-CoV-2 Also an Enteric Pathogen with Potential Fecal-Oral Transmission: A COVID-19 Virological and Clinical Review. Gastroenterology. PMID 32353371 DOI: 10.1053/J.Gastro.2020.04.052 |
0.32 |
|
| 2020 |
de Jong YP, Liang TJ. Stem cell-derived HCV infection systems illustrate the bright future of human hepatocyte research. Gut. PMID 32350090 DOI: 10.1136/Gutjnl-2020-321216 |
0.565 |
|
| 2020 |
Hsu CS, Liu WL, Li Q, Lowey B, Hertz L, Chao YC, Liang TJ, Chen DS, Kao JH. Hepatitis C virus genotypes 1-3 infections regulate lipogenic signaling and suppress cholesterol biosynthesis in hepatocytes. Journal of the Formosan Medical Association = Taiwan Yi Zhi. PMID 32284164 DOI: 10.1016/J.Jfma.2020.03.018 |
0.537 |
|
| 2020 |
Cheng X, Uchida T, Xia Y, Umarova R, Liu CJ, Chen PJ, Gaggar A, Suri V, Mücke MM, Vermehren J, Zeuzem S, Teraoka Y, Osawa M, Aikata H, Tsuji K, ... ... Liang TJ, et al. Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection. The Journal of Clinical Investigation. PMID 32163375 DOI: 10.1172/Jci135616 |
0.586 |
|
| 2019 |
Rolt A, O'Neill PM, Liang TJ, Stachulski AV. Synthesis of MeBmt and related derivatives syn-selective ATH-DKR. Rsc Advances. 9: 40336-40339. PMID 32864110 DOI: 10.1039/C9Ra08256E |
0.731 |
|
| 2019 |
Lowey B, Hertz L, Chiu S, Valdez K, Li Q, Liang TJ. Erratum for Lowey et al., "Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122". Mbio. 10. PMID 31796541 DOI: 10.1128/Mbio.02771-19 |
0.392 |
|
| 2019 |
Lowey B, Hertz L, Chiu S, Valdez K, Li Q, Liang TJ. Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122. Mbio. 10. PMID 31363036 DOI: 10.1128/Mbio.01617-19 |
0.523 |
|
| 2019 |
Surana P, Kapuria D, Broadwell C, Wright EC, Takyar V, Kleiner DE, Ghany MG, Ben-Yakov G, Heller T, Liang TJ, Koh C. Longitudinal effects of Nucleos(t)ide analogue therapy in chronic hepatitis B patients and the utility of non-invasive fibrosis markers during treatment: A single-center experience for up to 17 years. Antiviral Research. PMID 31125632 DOI: 10.1016/J.Antiviral.2019.05.007 |
0.404 |
|
| 2019 |
Li Y, Xia Y, Cheng X, Kleiner DE, Hewitt SM, Sproch J, Li T, Zhuang H, Liang TJ. Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B. Viruses. 11. PMID 31027244 DOI: 10.3390/V11040386 |
0.46 |
|
| 2019 |
Revill PA, Chisari FV, Block JM, Dandri M, Gehring AJ, Guo H, Hu J, Kramvis A, Lampertico P, Janssen HLA, Levrero M, Li W, Liang TJ, Lim SG, Lu F, et al. A global scientific strategy to cure hepatitis B. The Lancet. Gastroenterology & Hepatology. PMID 30981686 DOI: 10.1016/S2468-1253(19)30119-0 |
0.456 |
|
| 2019 |
Park SB, Boyer A, Hu Z, Le D, Liang TJ. Discovery and characterization of a novel HCV inhibitor targeting the late stage of HCV life cycle. Antiviral Therapy. PMID 30880685 DOI: 10.3851/Imp3303 |
0.492 |
|
| 2019 |
Koh C, Dubey P, Han MAT, Walter PJ, Garraffo HM, Surana P, Southall NT, Borochov N, Uprichard SL, Cotler SJ, Etzion O, Heller T, Dahari H, Liang TJ. A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C. Antiviral Research. PMID 30711416 DOI: 10.1016/J.Antiviral.2019.01.017 |
0.559 |
|
| 2019 |
Cox AL, Page K, Melia M, Veenhuis R, Massaccesi G, Osburn W, Wagner K, Giudice L, Stein E, Asher AK, Vassilev V, Lin L, Nicosia A, Capone S, Scarselli E, ... ... Liang TJ, et al. LB10. A Randomized, Double-Blind, Placebo-Controlled Efficacy Trial of a Vaccine to Prevent Chronic Hepatitis C Virus Infection in an at-Risk Population Open Forum Infectious Diseases. 6: S997-S997. DOI: 10.1093/Ofid/Ofz415.2493 |
0.414 |
|
| 2019 |
Rolt A, O'Neill PM, Liang TJ, Stachulski AV. Synthesis of MeBmt and related derivatives via syn-selective ATH-DKR Rsc Advances. 9: 40336-40339. DOI: 10.1039/c9ra08256e |
0.537 |
|
| 2018 |
Liang TJ, Terrault N. Viral Hepatitis and Hepatocellular Carcinoma. Gastroenterology. 156: 293. PMID 30593765 DOI: 10.1053/J.Gastro.2018.12.016 |
0.399 |
|
| 2018 |
Ma Y, Belyaeva OV, Brown PM, Fujita K, Valles K, Karki S, de Boer YS, Koh C, Chen Y, Du X, Handelman SK, Chen V, Speliotes EK, Nestlerode C, Thomas E, ... ... Liang TJ, et al. HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non-Alcoholic Fatty Liver Disease. Hepatology (Baltimore, Md.). PMID 30415504 DOI: 10.1002/Hep.30350 |
0.586 |
|
| 2018 |
Xia Y, Liang TJ. Development of Direct-acting Antiviral and Host-targeting Agents for Treatment of HBV Infection. Gastroenterology. PMID 30243618 DOI: 10.1053/J.Gastro.2018.07.057 |
0.438 |
|
| 2018 |
Boyer A, Park SB, de Boer Y, Li Q, Liang TJ. TM6SF2 Promotes Lipidation and Secretion of Hepatitis C Virus in Infected Hepatocytes. Gastroenterology. PMID 30144428 DOI: 10.1053/J.Gastro.2018.08.027 |
0.544 |
|
| 2018 |
Xia Y, Cheng X, Li Y, Valdez K, Chen W, Liang TJ. Hepatitis B virus deregulates cell cycle to promote viral replication and a premalignant phenotype. Journal of Virology. PMID 30021897 DOI: 10.1128/Jvi.00722-18 |
0.423 |
|
| 2018 |
Alao H, Cam M, Keembiyehetty C, Zhang F, Serti E, Suarez D, Park H, Fourie NH, Wright EC, Henderson WA, Li Q, Liang TJ, Rehermann B, Ghany MG. Baseline Intrahepatic and Peripheral Innate Immunity are Associated with Hepatitis C Virus Clearance During DAA Therapy. Hepatology (Baltimore, Md.). PMID 29704252 DOI: 10.1002/Hep.29921 |
0.541 |
|
| 2018 |
Rolt A, Le D, Hu Z, Wang AQ, Shah P, Singleton M, Hughes E, Dulcey AE, He S, Imamura M, Uchida T, Chayama K, Xu X, Marugan JJ, Liang TJ. Preclinical Pharmacological Development of Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. The Journal of Infectious Diseases. PMID 29373739 DOI: 10.1093/Infdis/Jiy039 |
0.822 |
|
| 2017 |
Li Q, Lowey B, Sodroski C, Krishnamurthy S, Alao H, Cha H, Chiu S, El-Diwany R, Ghany MG, Liang TJ. Cellular microRNA networks regulate host dependency of hepatitis C virus infection. Nature Communications. 8: 1789. PMID 29176620 DOI: 10.1038/s41467-017-01954-x |
0.351 |
|
| 2017 |
Schweitzer CJ, Zhang F, Boyer A, Valdez K, Cam M, Liang TJ. N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly. Journal of Virology. PMID 29118118 DOI: 10.1128/Jvi.01166-17 |
0.571 |
|
| 2017 |
Bolte FJ, O'Keefe AC, Webb LM, Serti E, Rivera E, Liang TJ, Ghany M, Rehermann B. Intra-hepatic Depletion of Mucosal Associated Invariant T cells in Hepatitis C Virus-induced Liver Inflammation. Gastroenterology. PMID 28780074 DOI: 10.1053/J.Gastro.2017.07.043 |
0.524 |
|
| 2017 |
Cheng X, Xia Y, Serti E, Block PD, Chung M, Chayama K, Rehermann B, Liang TJ. Hepatitis B virus evades innate immunity of hepatocytes but activates macrophages during infection. Hepatology (Baltimore, Md.). PMID 28665004 DOI: 10.1002/Hep.29348 |
0.464 |
|
| 2017 |
He S, Li K, Lin B, Hu Z, Xiao J, Hu X, Wang AQ, Xu X, Ferrer M, Southall N, Zheng W, Aubé J, Schoenen FJ, Marugan JJ, Liang TJ, et al. The Development of an Aryloxazole Class of Hepatitis C Virus Inhibitors Targeting the Entry Stage of the Viral Replication Cycle. Journal of Medicinal Chemistry. PMID 28636348 DOI: 10.1021/Acs.Jmedchem.7B00561 |
0.555 |
|
| 2017 |
Loomba R, Liang TJ. Hepatitis B reactivation associated with immune suppressive and biological modifier therapies: current concepts, management strategies and future directions. Gastroenterology. PMID 28219691 DOI: 10.1053/J.Gastro.2017.02.009 |
0.426 |
|
| 2017 |
Takyar V, Etzion O, Heller T, Kleiner DE, Rotman Y, Ghany MG, Fryzek N, Williams VH, Rivera E, Auh S, Liang TJ, Hoofnagle JH, Koh C. Complications of percutaneous liver biopsy with Klatskin needles: a 36-year single-centre experience. Alimentary Pharmacology & Therapeutics. PMID 28074540 DOI: 10.1111/Apt.13939 |
0.566 |
|
| 2016 |
Takyar V, Surana P, Kleiner DE, Wilkins K, Hoofnagle JH, Liang TJ, Heller T, Koh C. Noninvasive markers for staging fibrosis in chronic delta hepatitis. Alimentary Pharmacology & Therapeutics. PMID 27813124 DOI: 10.1111/apt.13834 |
0.435 |
|
| 2016 |
Liang TJ. Hepatitis C Virus: from Obscurity to the Lasker. Gastroenterology. PMID 27765691 DOI: 10.1053/J.Gastro.2016.10.011 |
0.502 |
|
| 2016 |
Zhang F, Sodroski C, Cha H, Li Q, Liang TJ. Infection of Hepatocytes with HCV Increases Cell Surface Levels of Heparan Sulfate Proteoglycans, Uptake of Cholesterol and Lipoprotein, and Virus Entry by Upregulating SMAD6 and SMAD7. Gastroenterology. PMID 27693511 DOI: 10.1053/j.gastro.2016.09.033 |
0.428 |
|
| 2016 |
Li Q, Sodroski C, Lowey B, Schweitzer CJ, Cha H, Zhang F, Liang TJ. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298373 DOI: 10.1073/Pnas.1602701113 |
0.435 |
|
| 2016 |
Thomas E, Liang TJ. Experimental models of hepatitis B and C - new insights and progress. Nature Reviews. Gastroenterology & Hepatology. PMID 27075261 DOI: 10.1038/Nrgastro.2016.37 |
0.505 |
|
| 2016 |
Carpentier A, Nimgaonkar I, Chu V, Xia Y, Hu Z, Liang TJ. Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen. Stem Cell Research. 16: 640-650. PMID 27062358 DOI: 10.1016/J.Scr.2016.03.009 |
0.353 |
|
| 2016 |
Lin B, He S, Yim HJ, Liang TJ, Hu Z. Evaluation of antiviral drug synergy in an infectious HCV system. Antiviral Therapy. PMID 27035622 DOI: 10.3851/Imp3044 |
0.54 |
|
| 2016 |
Serti E, Park H, Keane M, O'Keefe AC, Rivera E, Liang TJ, Ghany M, Rehermann B. Rapid decrease in hepatitis C viremia by direct acting antivirals improves the natural killer cell response to IFNα. Gut. PMID 26733671 DOI: 10.1136/Gutjnl-2015-310033 |
0.52 |
|
| 2016 |
Schweitzer CJ, Liang TJ. Border Control in Hepatitis C Virus Infection: Inhibiting Viral Entry Acs Infectious Diseases. 1: 416-419. DOI: 10.1021/acsinfecdis.5b00060 |
0.478 |
|
| 2016 |
Ghany MG, Liang TJ. Natural History of Chronic Hepatitis C Revista Portuguesa De Pneumologia. 3-55. DOI: 10.1007/978-4-431-56101-9_1 |
0.472 |
|
| 2015 |
Schweitzer CJ, Liang TJ. Border Control in Hepatitis C Virus Infection: Inhibiting Viral Entry. Acs Infectious Diseases. 1: 416-419. PMID 27617924 DOI: 10.1021/Acsinfecdis.5B00060 |
0.566 |
|
| 2015 |
He S, Xiao J, Dulcey AE, Lin B, Rolt A, Hu Z, Hu X, Wang AQ, Xu X, Southall N, Ferrer M, Zheng W, Liang TJ, Marugan JJ. Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. Journal of Medicinal Chemistry. PMID 26599718 DOI: 10.1021/Acs.Jmedchem.5B00752 |
0.816 |
|
| 2015 |
Hu Z, Hu X, He S, Yim HJ, Xiao J, Swaroop M, Tanega C, Zhang YQ, Yi G, Kao CC, Marugan J, Ferrer M, Zheng W, Southall N, Liang TJ. Identification of Novel Anti-Hepatitis C Virus Agents by a Quantitative High Throughput Screen in a Cell-Based Infection Assay. Antiviral Research. PMID 26515788 DOI: 10.1016/J.Antiviral.2015.10.018 |
0.53 |
|
| 2015 |
Zoulim F, Liang TJ, Gerbes AL, Aghemo A, Deuffic-Burban S, Dusheiko G, Fried MW, Pol S, Rockstroh JK, Terrault NA, Wiktor S. Hepatitis C virus treatment in the real world: optimising treatment and access to therapies. Gut. 64: 1824-33. PMID 26449729 DOI: 10.1136/Gutjnl-2015-310421 |
0.517 |
|
| 2015 |
Sarkar S, Rivera EM, Engle RE, Nguyen HT, Schechterly CA, Alter HJ, Liang TJ, Purcell RH, Hoofnagle JH, Ghany MG. An Epidemiologic Investigation Of A Case Of Acute Hepatitis E. Journal of Clinical Microbiology. PMID 26338861 DOI: 10.1128/Jcm.01189-15 |
0.335 |
|
| 2015 |
He S, Jain P, Lin B, Ferrer M, Hu Z, Southall N, Hu X, Zheng W, Neuenswander B, Cho CH, Chen Y, Worlikar SA, Aubé J, Larock RC, Schoenen FJ, ... ... Liang TJ, et al. High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors. Acs Combinatorial Science. PMID 26332742 DOI: 10.1021/Acscombsci.5B00101 |
0.448 |
|
| 2015 |
Liang TJ, Block TM, McMahon BJ, Ghany MG, Urban S, Guo JT, Locarnini S, Zoulim F, Chang KM, Lok AS. Present and future therapies of hepatitis B: From discovery to cure. Hepatology (Baltimore, Md.). PMID 26239691 DOI: 10.1002/Hep.28025 |
0.409 |
|
| 2015 |
Noureddin M, Rotman Y, Zhang F, Park H, Rehermann B, Thomas E, Liang TJ. Hepatic expression levels of interferons and interferon-stimulated genes in patients with chronic hepatitis C: A phenotype-genotype correlation study. Genes and Immunity. 16: 321-9. PMID 26020282 DOI: 10.1038/Gene.2015.11 |
0.685 |
|
| 2015 |
He S, Lin B, Chu V, Hu Z, Hu X, Xiao J, Wang AQ, Schweitzer CJ, Li Q, Imamura M, Hiraga N, Southall N, Ferrer M, Zheng W, Chayama K, ... ... Liang TJ, et al. Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection. Science Translational Medicine. 7: 282ra49. PMID 25855495 DOI: 10.1126/Scitranslmed.3010286 |
0.56 |
|
| 2015 |
Lepiller Q, Soulier E, Li Q, Lambotin M, Barths J, Fuchs D, Stoll-Keller F, Liang TJ, Barth H. Antiviral and Immunoregulatory Effects of Indoleamine-2,3-Dioxygenase in Hepatitis C Virus Infection. Journal of Innate Immunity. PMID 25792183 DOI: 10.1159/000375161 |
0.559 |
|
| 2015 |
Serti E, Chepa-Lotrea X, Kim YJ, Keane M, Fryzek N, Liang TJ, Ghany M, Rehermann B. Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function. Gastroenterology. 149: 190-200.e2. PMID 25754160 DOI: 10.1053/J.Gastro.2015.03.004 |
0.484 |
|
| 2015 |
Pène V, Li Q, Sodroski C, Hsu CS, Liang TJ. Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection. Journal of Virology. 89: 5462-77. PMID 25740981 DOI: 10.1128/Jvi.03197-14 |
0.522 |
|
| 2015 |
Gara N, Abdalla A, Rivera E, Zhao X, Werner JM, Liang TJ, Hoofnagle JH, Rehermann B, Ghany MG. Durability of antibody response against hepatitis B virus in healthcare workers vaccinated as adults. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 505-13. PMID 25389254 DOI: 10.1093/Cid/Ciu867 |
0.321 |
|
| 2014 |
Ghany MG, Liang TJ. Building bridges and providing transparency to the hepatitis C virus drug approval process. Gastroenterology. 147: 1201-3. PMID 25449025 DOI: 10.1053/J.Gastro.2014.10.028 |
0.425 |
|
| 2014 |
Carpentier A, Tesfaye A, Chu V, Nimgaonkar I, Zhang F, Lee SB, Thorgeirsson SS, Feinstone SM, Liang TJ. Engrafted human stem cell-derived hepatocytes establish an infectious HCV murine model. The Journal of Clinical Investigation. 124: 4953-64. PMID 25295540 DOI: 10.1172/Jci75456 |
0.52 |
|
| 2014 |
Guedj J, Rotman Y, Cotler SJ, Koh C, Schmid P, Albrecht J, Haynes-Williams V, Liang TJ, Hoofnagle JH, Heller T, Dahari H. Understanding early serum hepatitis D virus and hepatitis B surface antigen kinetics during pegylated interferon-alpha therapy via mathematical modeling. Hepatology (Baltimore, Md.). 60: 1902-10. PMID 25098971 DOI: 10.1002/Hep.27357 |
0.68 |
|
| 2014 |
Li Q, Zhang YY, Chiu S, Hu Z, Lan KH, Cha H, Sodroski C, Zhang F, Hsu CS, Thomas E, Liang TJ. Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle. Plos Pathogens. 10: e1004163. PMID 24852294 DOI: 10.1371/Journal.Ppat.1004163 |
0.419 |
|
| 2014 |
Sugiyama N, Murayama A, Suzuki R, Watanabe N, Shiina M, Liang TJ, Wakita T, Kato T. Single strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection. Plos One. 9: e98168. PMID 24848954 DOI: 10.1371/Journal.Pone.0098168 |
0.407 |
|
| 2014 |
Heller T, Rotman Y, Koh C, Clark S, Haynes-Williams V, Chang R, McBurney R, Schmid P, Albrecht J, Kleiner DE, Ghany MG, Liang TJ, Hoofnagle JH. Long-term therapy of chronic delta hepatitis with peginterferon alfa. Alimentary Pharmacology & Therapeutics. 40: 93-104. PMID 24815494 DOI: 10.1111/Apt.12788 |
0.663 |
|
| 2014 |
Liang TJ, Ghany MG. Therapy of hepatitis C--back to the future. The New England Journal of Medicine. 370: 2043-7. PMID 24795199 DOI: 10.1056/Nejme1403619 |
0.539 |
|
| 2014 |
Werner JM, Serti E, Chepa-Lotrea X, Stoltzfus J, Ahlenstiel G, Noureddin M, Feld JJ, Liang TJ, Rotman Y, Rehermann B. Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection. Hepatology (Baltimore, Md.). 60: 1160-9. PMID 24700342 DOI: 10.1002/Hep.27092 |
0.68 |
|
| 2014 |
Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, Sprinzl MF, Koppensteiner H, Makowska Z, Volz T, Remouchamps C, Chou WM, Thasler WE, Hüser N, Durantel D, ... Liang TJ, et al. Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA. Science (New York, N.Y.). 343: 1221-8. PMID 24557838 DOI: 10.1126/Science.1243462 |
0.43 |
|
| 2014 |
Koh C, Liang TJ. What is the future of ribavirin therapy for hepatitis C? Antiviral Research. 104: 34-9. PMID 24468277 DOI: 10.1016/J.Antiviral.2014.01.005 |
0.531 |
|
| 2014 |
Alao H, Liang TJ. Alternative interferons and immunomodulators in the treatment of hepatitis C. Liver International. 34: 133-138. PMID 24373090 DOI: 10.1111/Liv.12402 |
0.438 |
|
| 2014 |
Hu Z, Lan KH, He S, Swaroop M, Hu X, Southall N, Zheng W, Liang TJ. Novel cell-based hepatitis C virus infection assay for quantitative high-throughput screening of anti-hepatitis C virus compounds. Antimicrobial Agents and Chemotherapy. 58: 995-1004. PMID 24277038 DOI: 10.1128/Aac.02094-13 |
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| 2014 |
Brownell J, Bruckner J, Wagoner J, Thomas E, Loo YM, Gale M, Liang TJ, Polyak SJ. Direct, interferon-independent activation of the CXCL10 promoter by NF-κB and interferon regulatory factor 3 during hepatitis C virus infection. Journal of Virology. 88: 1582-90. PMID 24257594 DOI: 10.1128/Jvi.02007-13 |
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| 2014 |
Hara K, Rivera MM, Koh C, Demino M, Page S, Nagabhyru PR, Rehermann B, Liang TJ, Hoofnagle JH, Heller T. Sequence analysis of hepatitis C virus from patients with relapse after a sustained virological response: relapse or reinfection? The Journal of Infectious Diseases. 209: 38-45. PMID 24127561 DOI: 10.1093/Infdis/Jit541 |
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| 2014 |
Rotman Y, Noureddin M, Feld JJ, Guedj J, Witthaus M, Han H, Park YJ, Park SH, Heller T, Ghany MG, Doo E, Koh C, Abdalla A, Gara N, Sarkar S, ... ... Liang TJ, et al. Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C. Gut. 63: 161-9. PMID 23396509 DOI: 10.1136/Gutjnl-2012-303852 |
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| 2014 |
Hu Z, Lan K, He S, Swaroop M, Hu X, Southall N, Zheng W, Liang TJ. Novel Cell-Based Hepatitis C Virus Infection Assay for Quantitative High-Throughput Screening of Anti-Hepatitis C Virus Compounds Antimicrobial Agents and Chemotherapy. 58: 2995-2995. DOI: 10.1128/Aac.02529-14 |
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| 2014 |
Han H, Noureddin M, Witthaus M, Park YJ, Hoofnagle JH, Liang TJ, Rotman Y. Corrigendum to “Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype” [J Hepatol 2013; 59:957–963] Journal of Hepatology. 60: 1334-1335. DOI: 10.1016/J.Jhep.2014.02.005 |
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| 2013 |
Ghany MG, Liang TJ. Current and future therapies for hepatitis C virus infection. The New England Journal of Medicine. 369: 679-80. PMID 23944318 DOI: 10.1056/NEJMc1307589 |
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| 2013 |
Han H, Noureddin M, Witthaus M, Park YJ, Hoofnagle JH, Liang TJ, Rotman Y. Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype. Journal of Hepatology. 59: 957-63. PMID 23850879 DOI: 10.1016/J.Jhep.2013.07.004 |
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| 2013 |
Liang TJ. Current progress in development of hepatitis C virus vaccines. Nature Medicine. 19: 869-78. PMID 23836237 DOI: 10.1038/Nm.3183 |
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| 2013 |
Schweitzer CJ, Liang TJ. Impact of host and virus genome variability on HCV replication and response to interferon. Current Opinion in Virology. 3: 501-7. PMID 23835049 DOI: 10.1016/J.Coviro.2013.06.005 |
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| 2013 |
Koh C, Zhao X, Samala N, Sakiani S, Liang TJ, Talwalkar JA. AASLD clinical practice guidelines: a critical review of scientific evidence and evolving recommendations. Hepatology (Baltimore, Md.). 58: 2142-52. PMID 23775835 DOI: 10.1002/Hep.26578 |
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Li Q, Pène V, Krishnamurthy S, Cha H, Liang TJ. Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly. Nature Medicine. 19: 722-9. PMID 23708292 DOI: 10.1038/Nm.3190 |
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| 2013 |
Noureddin M, Wright EC, Alter HJ, Clark S, Thomas E, Chen R, Zhao X, Conry-Cantilena C, Kleiner DE, Liang TJ, Ghany MG. Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis. Hepatology (Baltimore, Md.). 58: 1548-57. PMID 23703931 DOI: 10.1002/Hep.26506 |
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Liang TJ, Ghany MG. Current and future therapies for hepatitis C virus infection. The New England Journal of Medicine. 368: 1907-17. PMID 23675659 DOI: 10.1056/Nejmra1213651 |
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Koh C, Heller T, Haynes-Williams V, Hara K, Zhao X, Feld JJ, Kleiner DE, Rotman Y, Ghany MG, Liang TJ, Hoofnagle JH. Long-term outcome of chronic hepatitis C after sustained virological response to interferon-based therapy. Alimentary Pharmacology & Therapeutics. 37: 887-94. PMID 23461575 DOI: 10.1111/Apt.12273 |
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Gara N, Zhao X, Kleiner DE, Liang TJ, Hoofnagle JH, Ghany MG. Discordance among transient elastography, aspartate aminotransferase to platelet ratio index, and histologic assessments of liver fibrosis in patients with chronic hepatitis C. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 11: 303-8.e1. PMID 23142332 DOI: 10.1016/J.Cgh.2012.10.044 |
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| 2013 |
Thomas E, Ghany MG, Liang TJ. The application and mechanism of action of ribavirin in therapy of hepatitis C. Antiviral Chemistry & Chemotherapy. 23: 1-12. PMID 22592135 DOI: 10.3851/Imp2125 |
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Lepiller Q, Soulier E, Lambotin M, Barths J, Bachellier P, Stoll-Keller F, Baumert T, Liang T, Barth H. 343 HUMAN HEPATOCYTE INDOLEAMINE-2,3-DIOXYGENASE CONTRIBUTES TO ANTIVIRAL DEFENSE AND IMMUNE REGULATION IN HEPATITIS C VIRUS INFECTION Journal of Hepatology. 58: S143. DOI: 10.1016/S0168-8278(13)60345-1 |
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| 2012 |
Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, ... ... Liang TJ, et al. Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity. Nature Medicine. 18: 1060-8. PMID 22706385 DOI: 10.1038/Nm.2811 |
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Ghany MG, Feld JJ, Zhao X, Heller T, Doo E, Rotman Y, Nagabhyru P, Koh C, Kleiner DE, Wright EC, Liang TJ, Hoofnagle JH. Randomised clinical trial: the benefit of combination therapy with adefovir and lamivudine for chronic hepatitis B. Alimentary Pharmacology & Therapeutics. 35: 1027-35. PMID 22449251 DOI: 10.1111/J.1365-2036.2012.05059.X |
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Alter HJ, Liang TJ. Hepatitis C: the end of the beginning and possibly the beginning of the end. Annals of Internal Medicine. 156: 317-8. PMID 22351718 DOI: 10.7326/0003-4819-156-4-201202210-00014 |
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Thomas E, Gonzalez VD, Li Q, Modi AA, Chen W, Noureddin M, Rotman Y, Liang TJ. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology. 142: 978-88. PMID 22248663 DOI: 10.1053/J.Gastro.2011.12.055 |
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Kandiah E, Watts NR, Cheng N, Cardone G, Stahl SJ, Heller T, Liang TJ, Wingfield PT, Steven AC. Cryo-EM study of Hepatitis B virus core antigen capsids decorated with antibodies from a human patient. Journal of Structural Biology. 177: 145-51. PMID 22056468 DOI: 10.1016/J.Jsb.2011.10.003 |
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Edlich B, Ahlenstiel G, Zabaleta Azpiroz A, Stoltzfus J, Noureddin M, Serti E, Feld JJ, Liang TJ, Rotman Y, Rehermann B. Early changes in interferon signaling define natural killer cell response and refractoriness to interferon-based therapy of hepatitis C patients. Hepatology (Baltimore, Md.). 55: 39-48. PMID 21898483 DOI: 10.1002/Hep.24628 |
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Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Arlt A, Günther R, Hampe J, Schreiber S, Baron J, Moody DB, Liang TJ, Blumberg RS. 742 Hepatitis B Virus Infection Leads to Alterations in the Repertoire of Self Lipid Antigens Presented by Hepatocytes and is Associated With Direct and Indirect Activation of Natural Killer T Cells Gastroenterology. 142: S-927. DOI: 10.1016/S0016-5085(12)63596-3 |
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Ahlenstiel G, Edlich B, Hogdal LJ, Rotman Y, Noureddin M, Feld JJ, Holz LE, Titerence RH, Liang TJ, Rehermann B. Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C. Gastroenterology. 141: 1231-9, 1239.e1-2. PMID 21741920 DOI: 10.1053/J.Gastro.2011.06.069 |
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Sandler NG, Koh C, Roque A, Eccleston JL, Siegel RB, Demino M, Kleiner DE, Deeks SG, Liang TJ, Heller T, Douek DC. Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection. Gastroenterology. 141: 1220-30, 1230.e1-3. PMID 21726511 DOI: 10.1053/J.Gastro.2011.06.063 |
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Barth H, Rybczynska J, Patient R, Choi Y, Sapp RK, Baumert TF, Krawczynski K, Liang TJ. Both innate and adaptive immunity mediate protective immunity against hepatitis C virus infection in chimpanzees. Hepatology (Baltimore, Md.). 54: 1135-48. PMID 21674561 DOI: 10.1002/Hep.24489 |
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Saeed M, Shiina M, Date T, Akazawa D, Watanabe N, Murayama A, Suzuki T, Watanabe H, Hiraga N, Imamura M, Chayama K, Choi Y, Krawczynski K, Liang TJ, Wakita T, et al. In vivo adaptation of hepatitis C virus in chimpanzees for efficient virus production and evasion of apoptosis. Hepatology (Baltimore, Md.). 54: 425-33. PMID 21538444 DOI: 10.1002/Hep.24399 |
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Thomas E, Feld JJ, Li Q, Hu Z, Fried MW, Liang TJ. Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models. Hepatology (Baltimore, Md.). 53: 32-41. PMID 21254160 DOI: 10.1002/Hep.23985 |
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Loomba R, Rivera MM, McBurney R, Park Y, Haynes-Williams V, Rehermann B, Alter HJ, Herrine SK, Liang TJ, Hoofnagle JH, Heller T. The natural history of acute hepatitis C: clinical presentation, laboratory findings and treatment outcomes. Alimentary Pharmacology & Therapeutics. 33: 559-65. PMID 21198704 DOI: 10.1111/J.1365-2036.2010.04549.X |
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Veerapu NS, Raghuraman S, Liang TJ, Heller T, Rehermann B. Sporadic reappearance of minute amounts of hepatitis C virus RNA after successful therapy stimulates cellular immune responses. Gastroenterology. 140: 676-685.e1. PMID 21040725 DOI: 10.1053/J.Gastro.2010.10.048 |
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Feld JJ, Modi AA, El-Diwany R, Rotman Y, Thomas E, Ahlenstiel G, Titerence R, Koh C, Cherepanov V, Heller T, Ghany MG, Park Y, Hoofnagle JH, Liang TJ. S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders. Gastroenterology. 140: 830-9. PMID 20854821 DOI: 10.1053/J.Gastro.2010.09.010 |
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Koh C, Sandler NG, Roque A, Eccleston J, Kleiner DE, Hoofnagle J, Liang TJ, Douek D, Heller T. Markers of Microbial Translocation Are Elevated in Hepatitis B (HBV) and Hepatitis C (HCV) Infection; A Window Into Biology and Surrogate Markers for Detecting Disease Progression Gastroenterology. 140: S-897. DOI: 10.1016/S0016-5085(11)63724-4 |
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Zeissig S, Murata K, Hu Z, Kaser A, Dougan SK, Bosse E, Scapa EF, Cohen DE, Arlt A, Franke A, Schreiber S, Liang TJ, Blumberg RS. Early Alterations in Endogenous Hepatocyte Lipid Antigens in Hepatitis B Virus Infection Are Associated With CD1D-Restricted Natural Killer T Cell Activation and Viral Clearance Gastroenterology. 140: S-886. DOI: 10.1016/S0016-5085(11)63685-8 |
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Thomas E, Gonzalez VD, Li Q, Modi AA, Uccellini L, Thomas JM, Chen W, Noureddin M, Rotman Y, Liang TJ. PS1-125 A robust induction of type III interferons and chemokines defines a unique pattern of hepatic innate immunity in response to hepatitis C virus infection Cytokine. 56: 49. DOI: 10.1016/J.Cyto.2011.07.158 |
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Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). 52: 894-903. PMID 20684021 DOI: 10.1002/Hep.23759 |
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Zhang Z, Sun E, Ou JH, Liang TJ. Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo. Journal of Virology. 84: 9326-31. PMID 20592087 DOI: 10.1128/Jvi.00579-10 |
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de Mochel NS, Seronello S, Wang SH, Ito C, Zheng JX, Liang TJ, Lambeth JD, Choi J. Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection. Hepatology (Baltimore, Md.). 52: 47-59. PMID 20578128 DOI: 10.1002/Hep.23671 |
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Peters MG, Weinbaum C, Tan L, Baine WB, Dienstag JL, Liang TJ, So S. Recommendations for prevention, screening, and diagnosis of HBV and HCV infections. The Journal of Family Practice. 59: S29-35. PMID 20398588 |
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Feld JJ, Lutchman GA, Heller T, Hara K, Pfeiffer JK, Leff RD, Meek C, Rivera M, Ko M, Koh C, Rotman Y, Ghany MG, Haynes-Williams V, Neumann AU, Liang TJ, et al. Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 139: 154-62.e4. PMID 20303352 DOI: 10.1053/J.Gastro.2010.03.037 |
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Rotman Y, Borg BB, Soza A, Feld JJ, Modi AA, Loomba R, Lutchman G, Rivera E, Doo E, Ghany MG, Heller T, Neumann AU, Liang TJ, Hoofnagle JH. Low- and standard-dose peginterferon alfa-2a for chronic hepatitis C, genotype 2 or 3: efficacy, tolerability, viral kinetics and cytokine response. Alimentary Pharmacology & Therapeutics. 31: 1018-27. PMID 20163377 DOI: 10.1111/J.1365-2036.2010.04263.X |
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Zhang YY, Zhang BH, Ishii K, Liang TJ. Novel function of CD81 in controlling hepatitis C virus replication. Journal of Virology. 84: 3396-407. PMID 20089661 DOI: 10.1128/Jvi.02391-09 |
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He XS, Nanda S, Ji X, Calderon-Rodriguez GM, Greenberg HB, Liang TJ. Differential transcriptional responses to interferon-alpha and interferon-gamma in primary human hepatocytes. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 311-20. PMID 20038212 DOI: 10.1089/Jir.2009.0082 |
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Modi AA, Feld JJ, Park Y, Kleiner DE, Everhart JE, Liang TJ, Hoofnagle JH. Increased caffeine consumption is associated with reduced hepatic fibrosis. Hepatology (Baltimore, Md.). 51: 201-9. PMID 20034049 DOI: 10.1002/Hep.23279 |
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Ahlenstiel G, Titerence RH, Koh C, Edlich B, Feld JJ, Rotman Y, Ghany MG, Hoofnagle JH, Liang TJ, Heller T, Rehermann B. Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner. Gastroenterology. 138: 325-35.e1-2. PMID 19747917 DOI: 10.1053/J.Gastro.2009.08.066 |
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Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, Elledge SJ. A genome-wide genetic screen for host factors required for hepatitis C virus propagation Proceedings of the National Academy of Sciences of the United States of America. 106: 16410-16415. PMID 19717417 DOI: 10.1073/Pnas.0907439106 |
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Palmore TN, Shah NL, Loomba R, Borg BB, Lopatin U, Feld JJ, Khokhar F, Lutchman G, Kleiner DE, Young NS, Childs R, Barrett AJ, Liang TJ, Hoofnagle JH, Heller T. Reactivation of hepatitis B with reappearance of hepatitis B surface antigen after chemotherapy and immunosuppression. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: 1130-7. PMID 19577007 DOI: 10.1016/J.Cgh.2009.06.027 |
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Rotman Y, Liang TJ. Coinfection with hepatitis C virus and human immunodeficiency virus: virological, immunological, and clinical outcomes. Journal of Virology. 83: 7366-74. PMID 19420073 DOI: 10.1128/Jvi.00191-09 |
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Heller T, Hoofnagle J, Liang TJ, Rehermann B. Acute hepatitis C. Gastroenterology. 136: 2411. PMID 19409987 DOI: 10.1053/J.Gastro.2009.04.042 |
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Liang TJ. Hepatitis B: the virus and disease. Hepatology (Baltimore, Md.). 49: S13-21. PMID 19399811 DOI: 10.1002/Hep.22881 |
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Matsumura T, Hu Z, Kato T, Dreux M, Zhang YY, Imamura M, Hiraga N, Juteau JM, Cosset FL, Chayama K, Vaillant A, Liang TJ. Amphipathic DNA polymers inhibit hepatitis C virus infection by blocking viral entry. Gastroenterology. 137: 673-81. PMID 19394333 DOI: 10.1053/J.Gastro.2009.04.048 |
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Yee LJ, Im K, Borg B, Yang H, Liang TJ. Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection. Genes and Immunity. 10: 365-72. PMID 19387461 DOI: 10.1038/gene.2009.26 |
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Koh C, Liang TJ. Settling the "score" with liver cancer. Journal of Hepatology. 50: 7-9. PMID 19014877 DOI: 10.1016/J.Jhep.2008.10.008 |
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Yee LJ, Im K, Wahed AS, Bugawan T, Li J, Rhodes SL, Erlich H, Rosen HR, Liang TJ, Yang H. Polymorphism in the human major histocompatibility complex and early viral decline during treatment of chronic hepatitis C. Antimicrobial Agents and Chemotherapy. 53: 615-21. PMID 18852273 DOI: 10.1128/Aac.00947-08 |
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Thomas E, Li Q, Clark SA, Feld JJ, Liang TJ. Characterization of gene induction and antiviral effects on HCVcc following ribavirin, interferon and polyIC stimulation Cytokine. 48: 85. DOI: 10.1016/J.Cyto.2009.07.305 |
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Nanda S, Havert MB, Calderón GM, Thomson M, Jacobson C, Kastner D, Liang TJ. Hepatic transcriptome analysis of hepatitis C virus infection in chimpanzees defines unique gene expression patterns associated with viral clearance. Plos One. 3: e3442. PMID 18927617 DOI: 10.1371/Journal.Pone.0003442 |
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Kato T, Choi Y, Elmowalid G, Sapp RK, Barth H, Furusaka A, Mishiro S, Wakita T, Krawczynski K, Liang TJ. Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation. Hepatology (Baltimore, Md.). 48: 732-40. PMID 18712792 DOI: 10.1002/Hep.22422 |
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Su X, Yee LJ, Im K, Rhodes SL, Tang Y, Tong X, Howell C, Ramcharran D, Rosen HR, Taylor MW, Liang TJ, Yang H. Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C. Journal of Hepatology. 49: 184-91. PMID 18571276 DOI: 10.1016/J.Jhep.2008.04.011 |
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Barth H, Robinet E, Liang TJ, Baumert TF. Mouse models for the study of HCV infection and virus-host interactions. Journal of Hepatology. 49: 134-42. PMID 18457898 DOI: 10.1016/J.Jhep.2008.03.012 |
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Loomba R, Rowley AK, Wesley R, Smith KG, Liang TJ, Pucino F, Csako G. Hepatitis B immunoglobulin and Lamivudine improve hepatitis B-related outcomes after liver transplantation: meta-analysis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 696-700. PMID 18456569 DOI: 10.1016/J.Cgh.2008.02.055 |
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Feld JJ, Hussain N, Wright EC, Kleiner DE, Hoofnagle JH, Ahlawat S, Anderson V, Hilligoss D, Gallin JI, Liang TJ, Malech HL, Holland SM, Heller T. Hepatic involvement and portal hypertension predict mortality in chronic granulomatous disease. Gastroenterology. 134: 1917-26. PMID 18439425 DOI: 10.1053/J.Gastro.2008.02.081 |
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Rhodes SL, Erlich H, Im KA, Wang J, Li J, Bugawan T, Jeffers L, Tong X, Su X, Rosen HR, Yee LJ, Liang TJ, Yang H. Associations between the human MHC and sustained virologic response in the treatment of chronic hepatitis C virus infection. Genes and Immunity. 9: 328-33. PMID 18418397 DOI: 10.1038/gene.2008.21 |
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Loomba R, Rowley A, Wesley R, Liang TJ, Hoofnagle JH, Pucino F, Csako G. Systematic review: the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy. Annals of Internal Medicine. 148: 519-28. PMID 18378948 DOI: 10.7326/0003-4819-148-7-200804010-00008 |
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Loomba R, Liang TJ. Treatment of chronic hepatitis B. Antiviral Therapy. H33-41. PMID 18284181 |
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Pawlotsky JM, Dusheiko G, Hatzakis A, Lau D, Lau G, Liang TJ, Locarnini S, Martin P, Richman DD, Zoulim F. Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology. 134: 405-15. PMID 18242209 DOI: 10.1053/J.Gastro.2007.11.036 |
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Barth H, Schnober EK, Neumann-Haefelin C, Thumann C, Zeisel MB, Diepolder HM, Hu Z, Liang TJ, Blum HE, Thimme R, Lambotin M, Baumert TF. Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells. Journal of Virology. 82: 3466-79. PMID 18216094 DOI: 10.1128/Jvi.02478-07 |
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Modi AA, Liang TJ. Hepatitis C: a clinical review. Oral Diseases. 14: 10-4. PMID 18173443 DOI: 10.1111/j.1601-0825.2007.01419.x |
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Chung RT, Gale M, Polyak SJ, Lemon SM, Liang TJ, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology (Baltimore, Md.). 47: 306-20. PMID 18161743 DOI: 10.1002/Hep.22070 |
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Loomba R, Rowley AK, Wesley R, Liang TJ, Pucino F, Csako G. M1874 Hepatitis B Immunoglobulin and Lamivudine Reduce Hepatitis B Virus-Related Morbidity and Mortality in Chronic Hepatitis B Patients Undergoing Liver Transplantation: Meta-Analysis Gastroenterology. 134: A-801. DOI: 10.1016/S0016-5085(08)63742-7 |
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Yee LJ, Im K, Wahed AS, Bugawan T, Li J, Rhodes SL, Erlich H, Rosen HR, Liang TJ, Yang H. 165 Polymorphism in the Human MHC and the Early Viral Decline During Treatment of HCV Gastroenterology. 134: A-756. DOI: 10.1016/S0016-5085(08)63530-1 |
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Thomas E, Hu Z, Dong S, Feld JJ, Liang TJ. 2 A novel innate immune antiviral mechanism of action of ribavirin in mammalian cells contributes to efficacy of combination therapy for hepatitis C Cytokine. 43: 237. DOI: 10.1016/J.Cyto.2008.07.042 |
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Feld JJ, Nanda S, Huang Y, Chen W, Cam M, Pusek SN, Schweigler LM, Theodore D, Zacks SL, Liang TJ, Fried MW. Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response Hepatology. 46: 1548-1563. PMID 17929300 DOI: 10.1002/Hep.21853 |
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Liang TJ. Shortened therapy for hepatitis C virus genotype 2 or 3 - Is less more? New England Journal of Medicine. 357: 176-178. PMID 17625131 DOI: 10.1056/Nejme078092 |
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Yu X, Qiao M, Atanasov I, Hu Z, Kato T, Liang TJ, Zhou ZH. Cryo-electron microscopy and three-dimensional reconstructions of hepatitis C virus particles. Virology. 367: 126-34. PMID 17618667 DOI: 10.1016/J.Virol.2007.05.038 |
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Lutchman G, Modi A, Kleiner DE, Promrat K, Heller T, Ghany M, Borg B, Loomba R, Liang TJ, Premkumar A, Hoofnagle JH. The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.). 46: 424-9. PMID 17559148 DOI: 10.1002/Hep.21661 |
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| 2007 |
Yee LJ, Tang YM, Kleiner DE, Wang D, Im K, Wahed A, Tong X, Rhodes S, Su X, Whelan RM, Fontana RJ, Ghany MG, Borg B, Liang TJ, Yang H, et al. Myxovirus-1 and protein kinase haplotypes and fibrosis in chronic hepatitis C virus. Hepatology (Baltimore, Md.). 46: 74-83. PMID 17526009 DOI: 10.1002/Hep.21636 |
0.453 |
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| 2007 |
Elmowalid GA, Qiao M, Jeong SH, Borg BB, Baumert TF, Sapp RK, Hu Z, Murthy K, Liang TJ. Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 104: 8427-32. PMID 17485666 DOI: 10.1073/Pnas.0702162104 |
0.535 |
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| 2007 |
Lutchman G, Danehower S, Song BC, Liang TJ, Hoofnagle JH, Thomson M, Ghany MG. Mutation Rate of the Hepatitis C Virus NS5B in Patients Undergoing Treatment With Ribavirin Monotherapy Gastroenterology. 132: 1757-1766. PMID 17484873 DOI: 10.1053/J.Gastro.2007.03.035 |
0.423 |
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| 2007 |
Ghany M, Liang TJ. Drug targets and molecular mechanisms of drug resistance in chronic hepatitis B. Gastroenterology. 132: 1574-85. PMID 17408658 DOI: 10.1053/J.Gastro.2007.02.039 |
0.335 |
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| 2007 |
Hoofnagle JH, Doo E, Liang TJ, Fleischer R, Lok AS. Management of hepatitis B: summary of a clinical research workshop. Hepatology (Baltimore, Md.). 45: 1056-75. PMID 17393513 DOI: 10.1002/Hep.21627 |
0.476 |
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| 2007 |
Hussain N, Feld JJ, Kleiner DE, Hoofnagle JH, Garcia-Eulate R, Ahlawat S, Koziel DE, Anderson V, Hilligoss D, Choyke P, Gallin JI, Liang TJ, Malech HL, Holland SM, Heller T. Hepatic abnormalities in patients with chronic granulomatous disease. Hepatology. 45: 675-683. PMID 17326162 DOI: 10.1002/Hep.21524 |
0.371 |
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| 2007 |
Kato T, Matsumura T, Heller T, Saito S, Sapp RK, Murthy K, Wakita T, Liang TJ. Production of infectious hepatitis C virus of various genotypes in cell cultures. Journal of Virology. 81: 4405-11. PMID 17301131 DOI: 10.1128/Jvi.02334-06 |
0.521 |
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| 2007 |
Huang Y, Feld JJ, Sapp RK, Nanda S, Lin JH, Blatt LM, Fried MW, Murthy K, Liang TJ. Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C. Gastroenterology. 132: 733-44. PMID 17258724 DOI: 10.1053/J.Gastro.2006.11.045 |
0.49 |
|
| 2007 |
Huang Y, Yang H, Borg BB, Su X, Rhodes SL, Yang K, Tong X, Tang G, Howell CD, Rosen HR, Thio CL, Thomas DL, Alter HJ, Sapp RK, Liang TJ. A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 104: 985-90. PMID 17215375 DOI: 10.1073/Pnas.0609954104 |
0.537 |
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| 2007 |
Huang Y, Yang H, Borg BB, Su X, Rhodes SL, Yang K, Tong X, Tang G, Howell CD, Rosen HR, Thio CL, Thomas DL, Alter HJ, Sapp RK, Liang TJ. Erratum: A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, (985-990) DOI: 10.1073/pnas.0609954104) Proceedings of the National Academy of Sciences of the United States of America. 104. DOI: 10.1073/Pnas.0701153104 |
0.447 |
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| 2006 |
Barth H, Liang TJ, Baumert TF. Hepatitis C virus entry: molecular biology and clinical implications. Hepatology (Baltimore, Md.). 44: 527-35. PMID 16941688 DOI: 10.1002/Hep.21321 |
0.561 |
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| 2006 |
Lutchman G, Promrat K, Kleiner DE, Heller T, Ghany MG, Yanovski JA, Liang TJ, Hoofnagle JH. Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 4: 1048-52. PMID 16814613 DOI: 10.1016/J.Cgh.2006.05.005 |
0.302 |
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| 2006 |
Perumalswami P, Kleiner DE, Lutchman G, Heller T, Borg B, Park Y, Liang TJ, Hoofnagle JH, Ghany MG. Steatosis and progression of fibrosis in untreated patients with chronic hepatitis C infection. Hepatology (Baltimore, Md.). 43: 780-7. PMID 16557550 DOI: 10.1002/Hep.21078 |
0.411 |
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| 2006 |
Nanda SK, Herion D, Liang TJ. The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity. Gastroenterology. 130: 794-809. PMID 16530520 DOI: 10.1053/J.Gastro.2005.12.030 |
0.467 |
|
| 2006 |
Loomba R, Liang TJ. Novel approaches to new therapies for hepatitis B virus infection. Antiviral Therapy. 11: 1-15. PMID 16518955 |
0.349 |
|
| 2006 |
Feld JJ, Liang TJ. Hepatitis C -- identifying patients with progressive liver injury. Hepatology (Baltimore, Md.). 43: S194-206. PMID 16447261 DOI: 10.1002/Hep.21065 |
0.434 |
|
| 2006 |
Hu Z, Zhang Z, Kim JW, Huang Y, Liang TJ. Altered proteolysis and global gene expression in hepatitis B virus X transgenic mouse liver. Journal of Virology. 80: 1405-13. PMID 16415018 DOI: 10.1128/Jvi.80.3.1405-1413.2006 |
0.449 |
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| 2006 |
Cai Z, Zhang C, Chang KS, Jiang J, Ahn BC, Wakita T, Liang TJ, Luo G. Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells. Journal of Virology. 79: 13963-73. PMID 16254332 DOI: 10.1128/Jvi.79.22.13963-13973.2005 |
0.542 |
|
| 2006 |
Ghany MG, Liang TJ. Natural history of hbeag-negative chronic Hepatitis b Current Hepatitis Reports. 5: 27-32. DOI: 10.1007/S11901-006-0020-1 |
0.482 |
|
| 2005 |
Balasubramanian A, Munshi N, Koziel MJ, Hu Z, Liang TJ, Groopman JE, Ganju RK. Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. The Journal of General Virology. 86: 3291-301. PMID 16298974 DOI: 10.1099/Vir.0.81056-0 |
0.486 |
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| 2005 |
Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, Murthy K, Habermann A, Kräusslich HG, Mizokami M, Bartenschlager R, Liang TJ. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nature Medicine. 11: 791-6. PMID 15951748 DOI: 10.1038/Nm1268 |
0.539 |
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| 2005 |
Heller T, Saito S, Auerbach J, Williams T, Moreen TR, Jazwinski A, Cruz B, Jeurkar N, Sapp R, Luo G, Liang TJ. An in vitro model of hepatitis C virion production. Proceedings of the National Academy of Sciences of the United States of America. 102: 2579-83. PMID 15701697 DOI: 10.1073/pnas.0409666102 |
0.313 |
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| 2005 |
Feld JJ, Liang TJ. HCV persistence: cure is still a four letter word. Hepatology (Baltimore, Md.). 41: 23-5. PMID 15690477 DOI: 10.1002/Hep.20561 |
0.462 |
|
| 2005 |
Baumert TF, Yang C, Schürmann P, Köck J, Ziegler C, Grüllich C, Nassal M, Liang TJ, Blum HE, von Weizsäcker F. Hepatitis B virus mutations associated with fulminant hepatitis induce apoptosis in primary Tupaia hepatocytes. Hepatology (Baltimore, Md.). 41: 247-56. PMID 15660384 DOI: 10.1002/Hep.20553 |
0.446 |
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| 2005 |
Barth H, Ulsenheimer A, Pape GR, Diepolder HM, Hoffmann M, Neumann-Haefelin C, Thimme R, Henneke P, Klein R, Paranhos-Baccalà G, Depla E, Liang TJ, Blum HE, Baumert TF. Uptake and presentation of hepatitis C virus-like particles by human dendritic cells. Blood. 105: 3605-14. PMID 15657184 DOI: 10.1182/Blood-2004-05-1952 |
0.499 |
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| 2005 |
Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, Murthy K, Habermann A, Kräusslich H, Mizokami M, Bartenschlager R, Liang TJ. Erratum: Corrigendum: Production of infectious hepatitis C virus in tissue culture from a cloned viral genome Nature Medicine. 11: 905-905. DOI: 10.1038/Nm0805-905B |
0.377 |
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| 2004 |
Liang TJ, Heller T. Pathogenesis of hepatitis C-associated hepatocellular carcinoma Gastroenterology. 127. PMID 15508105 DOI: 10.1053/J.Gastro.2004.09.017 |
0.533 |
|
| 2004 |
Steinmann D, Barth H, Gissler B, Schürmann P, Adah MI, Gerlach JT, Pape GR, Depla E, Jacobs D, Maertens G, Patel AH, Inchauspé G, Liang TJ, Blum HE, Baumert TF. Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C. Journal of Virology. 78: 9030-40. PMID 15308699 DOI: 10.1128/Jvi.78.17.9030-9040.2004 |
0.544 |
|
| 2004 |
Rahman F, Heller T, Sobao Y, Mizukoshi E, Nascimbeni M, Alter H, Herrine S, Hoofnagle J, Liang TJ, Rehermann B. Effects of antiviral therapy on the cellular immune response in acute hepatitis C. Hepatology (Baltimore, Md.). 40: 87-97. PMID 15239090 DOI: 10.1002/Hep.20253 |
0.534 |
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| 2004 |
Keck ZY, Sung VM, Perkins S, Rowe J, Paul S, Liang TJ, Lai MM, Foung SK. Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity. Journal of Virology. 78: 7257-63. PMID 15194801 DOI: 10.1128/Jvi.78.13.7257-7263.2004 |
0.494 |
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| 2004 |
Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ. Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates. Journal of Virology. 78: 6995-7003. PMID 15194776 DOI: 10.1128/Jvi.78.13.6995-7003.2004 |
0.505 |
|
| 2004 |
Zhang Z, Protzer U, Hu Z, Jacob J, Liang TJ. Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner. Journal of Virology. 78: 4566-72. PMID 15078938 DOI: 10.1128/Jvi.78.9.4566-4572.2004 |
0.43 |
|
| 2004 |
Cai Z, Liang TJ, Luo G. Effects of mutations of the initiation nucleotides on hepatitis C virus RNA replication in the cell. Journal of Virology. 78: 3633-43. PMID 15016884 DOI: 10.1128/Jvi.78.7.3633-3643.2004 |
0.423 |
|
| 2004 |
Promrat K, Lutchman G, Uwaifo GI, Freedman RJ, Soza A, Heller T, Doo E, Ghany M, Premkumar A, Park Y, Liang TJ, Yanovski JA, Kleiner DE, Hoofnagle JH. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.). 39: 188-96. PMID 14752837 DOI: 10.1002/Hep.20012 |
0.304 |
|
| 2004 |
Radaeva S, Jaruga B, Kim WH, Heller T, Liang TJ, Gao B. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C. The Biochemical Journal. 379: 199-208. PMID 14690454 DOI: 10.1042/Bj20031495 |
0.354 |
|
| 2003 |
Promrat K, Liang TJ. Chemokine systems and hepatitis C virus infection: is truth in the genes of the beholders? Hepatology (Baltimore, Md.). 38: 1359-62. PMID 14647045 DOI: 10.1016/J.Hep.2003.10.008 |
0.465 |
|
| 2003 |
Milich D, Liang TJ. Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection. Hepatology (Baltimore, Md.). 38: 1075-86. PMID 14578844 DOI: 10.1053/Jhep.2003.50453 |
0.443 |
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| 2003 |
Hoofnagle JH, Ghany MG, Kleiner DE, Doo E, Heller T, Promrat K, Ong J, Khokhar F, Soza A, Herion D, Park Y, Everhart JE, Liang TJ. Maintenance therapy with ribavirin in patients with chronic hepatitis C who fail to respond to combination therapy with interferon alfa and ribavirin. Hepatology (Baltimore, Md.). 38: 66-74. PMID 12829988 DOI: 10.1053/Jhep.2003.50258 |
0.513 |
|
| 2003 |
Murata K, Lechmann M, Qiao M, Gunji T, Alter HJ, Liang TJ. Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection. Proceedings of the National Academy of Sciences of the United States of America. 100: 6753-8. PMID 12748380 DOI: 10.1073/Pnas.1131929100 |
0.467 |
|
| 2003 |
Promrat K, McDermott DH, Gonzalez CM, Kleiner DE, Koziol DE, Lessie M, Merrell M, Soza A, Heller T, Ghany M, Park Y, Alter HJ, Hoofnagle JH, Murphy PM, Liang TJ. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C. Gastroenterology. 124: 352-60. PMID 12557141 DOI: 10.1053/Gast.2003.50061 |
0.492 |
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| 2003 |
Ghany MG, Kleiner DE, Alter H, Doo E, Khokar F, Promrat K, Herion D, Park Y, Liang TJ, Hoofnagle JH. Progression of fibrosis in chronic hepatitis C. Gastroenterology. 124: 97-104. PMID 12512034 DOI: 10.1053/Gast.2003.50018 |
0.44 |
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| 2003 |
Thomson M, Nascimbeni M, Havert MB, Major M, Gonzales S, Alter H, Feinstone SM, Murthy KK, Rehermann B, Liang TJ. The clearance of hepatitis C virus infection in chimpanzees may not necessarily correlate with the appearance of acquired immunity Journal of Virology. 77: 862-870. PMID 12502802 DOI: 10.1128/Jvi.77.2.862-870.2003 |
0.541 |
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| 2003 |
Qiao M, Murata K, Davis AR, Jeong SH, Liang TJ. Hepatitis C virus-like particles combined with novel adjuvant systems enhance virus-specific immune responses. Hepatology (Baltimore, Md.). 37: 52-9. PMID 12500188 DOI: 10.1053/Jhep.2003.50000 |
0.498 |
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| 2002 |
Soza A, Everhart JE, Ghany MG, Doo E, Heller T, Promrat K, Park Y, Liang TJ, Hoofnagle JH. Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C. Hepatology (Baltimore, Md.). 36: 1273-9. PMID 12395340 DOI: 10.1053/Jhep.2002.36502 |
0.485 |
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| 2002 |
Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, Liang TJ, Alter H, Rehermann B. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. Journal of Immunology (Baltimore, Md. : 1950). 169: 3447-58. PMID 12218168 DOI: 10.4049/Jimmunol.169.6.3447 |
0.526 |
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| 2002 |
Triyatni M, Saunier B, Maruvada P, Davis AR, Ulianich L, Heller T, Patel A, Kohn LD, Liang TJ. Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry. Journal of Virology. 76: 9335-44. PMID 12186916 DOI: 10.1128/Jvi.76.18.9335-9344.2002 |
0.484 |
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| 2002 |
Liang TJ, Ghany M. Hepatitis B e Antigen--the dangerous endgame of hepatitis B. The New England Journal of Medicine. 347: 208-10. PMID 12124411 DOI: 10.1056/Nejme020060 |
0.362 |
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| 2002 |
Triyatni M, Vergalla J, Davis AR, Hadlock KG, Foung SK, Liang TJ. Structural features of envelope proteins on hepatitis C virus-like particles as determined by anti-envelope monoclonal antibodies and CD81 binding. Virology. 298: 124-32. PMID 12093180 DOI: 10.1006/Viro.2002.1463 |
0.486 |
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| 2002 |
Mizukoshi E, Nascimbeni M, Blaustein JB, Mihalik K, Rice CM, Liang TJ, Feinstone SM, Rehermann B. Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune response and vaccination studies. Journal of Virology. 76: 6093-103. PMID 12021342 DOI: 10.1128/Jvi.76.12.6093-6103.2002 |
0.513 |
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| 2002 |
Zampino R, Marrone A, Cirillo G, del Giudice EM, Utili R, Karayiannis P, Liang TJ, Ruggiero G. Sequential analysis of hepatitis B virus core promoter and precore regions in cancer survivor patients with chronic hepatitis B before, during and after interferon treatment. Journal of Viral Hepatitis. 9: 183-8. PMID 12010505 DOI: 10.1046/j.1365-2893.2002.00347.x |
0.315 |
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| 2002 |
Lau JYN, Tam RC, Liang TJ, Hong Z. Mechanism of action of ribavirin in the combination treatment of chronic HCV infection Hepatology. 35: 1002-1009. PMID 11981750 DOI: 10.1053/Jhep.2002.32672 |
0.495 |
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| 2001 |
Zhang Z, Torii N, Hu Z, Jacob J, Liang TJ. X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo. The Journal of Clinical Investigation. 108: 1523-31. PMID 11714744 DOI: 10.1172/Jci13787 |
0.381 |
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| 2001 |
Satoi J, Murata K, Lechmann M, Manickan E, Zhang Z, Wedemeyer H, Rehermann B, Liang TJ. Genetic Immunization of Wild-Type and Hepatitis C Virus Transgenic Mice Reveals a Hierarchy of Cellular Immune Response and Tolerance Induction against Hepatitis C Virus Structural Proteins Journal of Virology. 75: 12121-12127. PMID 11711603 DOI: 10.1128/Jvi.75.24.12121-12127.2001 |
0.451 |
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| 2001 |
Thomson M, Nascimbeni M, Gonzales S, Murthy KK, Rehermann B, Liang TJ. Emergence of a distinct pattern of viral mutations in chimpanzees infected with a homogeneous inoculum of hepatitis C virus Gastroenterology. 121: 1226-1233. PMID 11677216 DOI: 10.1053/Gast.2001.28669 |
0.509 |
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| 2001 |
Kim WH, Hong F, Jaruga B, Hu Z, Fan S, Liang TJ, Gao B. Additive activation of hepatic NF-kappaB by ethanol and hepatitis B protein X (HBX) or HCV core protein: involvement of TNF-alpha receptor 1-independent and -dependent mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2551-3. PMID 11641261 DOI: 10.1096/Fj.01-0217 |
0.49 |
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| 2001 |
Cerino A, Meola A, Segagni L, Furione M, Marciano S, Triyatni M, Liang TJ, Nicosia A, Mondelli MU. Monoclonal antibodies with broad specificity for hepatitis C virus hypervariable region 1 variants can recognize viral particles. Journal of Immunology (Baltimore, Md. : 1950). 167: 3878-86. PMID 11564805 DOI: 10.4049/Jimmunol.167.7.3878 |
0.54 |
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| 2001 |
Lechmann M, Murata K, Satoi J, Vergalla J, Baumert TF, Liang TJ. Hepatitis C virus-like particles induce virus-specific humoral and cellular immune responses in mice. Hepatology. 34: 417-423. PMID 11481628 DOI: 10.1053/Jhep.2001.26523 |
0.459 |
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| 2001 |
Doo E, Liang TJ. Molecular anatomy and pathophysiologic implications of drug resistance in hepatitis B virus infection Gastroenterology. 120: 1000-1008. PMID 11231955 DOI: 10.1053/Gast.2001.22454 |
0.428 |
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| 2001 |
Ghany MG, Alter H, Boone MH, Doo E, Khokar F, Heller T, Park Y, Liang TJ, Hoofnagle JH. False pasitive results using commercial RT-PCR for hepatitis C virus (HCV) RNA: frequency and impact on clinical management Gastroenterology. 120: A368. DOI: 10.1016/S0016-5085(08)81831-8 |
0.502 |
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| 2000 |
Nemchinov LG, Liang TJ, Rifaat MM, Mazyad HM, Hadidi A, Keith JM. Development of a plant-derived subunit vaccine candidate against hepatitis C virus. Archives of Virology. 145: 2557-73. PMID 11205105 DOI: 10.1007/s007050070008 |
0.387 |
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| 2000 |
Lau DT, Khokhar MF, Doo E, Ghany MG, Herion D, Park Y, Kleiner DE, Schmid P, Condreay LD, Gauthier J, Kuhns MC, Liang TJ, Hoofnagle JH. Long-term therapy of chronic hepatitis B with lamivudine. Hepatology (Baltimore, Md.). 32: 828-34. PMID 11003630 DOI: 10.1053/Jhep.2000.17912 |
0.425 |
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| 2000 |
Baumert TF, Wellnitz S, Aono S, Satoi J, Herion D, Tilman Gerlach J, Pape GR, Lau JY, Hoofnagle JH, Blum HE, Liang TJ. Antibodies against hepatitis C virus-like particles and viral clearance in acute and chronic hepatitis C. Hepatology (Baltimore, Md.). 32: 610-7. PMID 10960457 DOI: 10.1053/Jhep.2000.9876 |
0.547 |
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| 2000 |
Lechmann M, Liang TJ. Vaccine development for hepatitis C. Seminars in Liver Disease. 20: 211-226. PMID 10946425 DOI: 10.1055/S-2000-9947 |
0.442 |
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| 2000 |
Zhang Z, Torii N, Furusaka A, Malayaman N, Hu Z, Liang TJ. Structural and Functional Characterization of Interaction between Hepatitis B Virus X Protein and the Proteasome Complex Journal of Biological Chemistry. 275: 15157-15165. PMID 10748218 DOI: 10.1074/Jbc.M910378199 |
0.386 |
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| 2000 |
Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH. Pathogenesis, natural history, treatment, and prevention of hepatitis C. Annals of Internal Medicine. 132: 296-305. PMID 10681285 DOI: 10.7326/0003-4819-132-4-200002150-00008 |
0.498 |
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| 2000 |
Thomson M, Liang TJ. I Molecular biology of hepatitis C virus Biomedical Research Reports. 2: 1-23. DOI: 10.1016/S1874-5326(00)80005-8 |
0.522 |
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| 1999 |
Baumert TF, Vergalla J, Satoi J, Thomson M, Lechmann M, Herion D, Greenberg HB, Ito S, Liang TJ. Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate Gastroenterology. 117: 1397-1407. PMID 10579981 DOI: 10.1016/S0016-5085(99)70290-8 |
0.509 |
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| 1999 |
Hu Z, Zhang Z, Doo E, Coux O, Goldberg AL, Liang TJ. Hepatitis B Virus X Protein Is both a Substrate and a Potential Inhibitor of the Proteasome Complex Journal of Virology. 73: 7231-7240. PMID 10438810 DOI: 10.1128/Jvi.73.9.7231-7240.1999 |
0.417 |
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| 1999 |
Reid AE, Koziel MJ, Aiza I, Jeffers L, Reddy R, Schiff E, Lau JY, Dienstag JL, Liang TJ. Hepatitis C virus genotypes and viremia and hepatocellular carcinoma in the United States. The American Journal of Gastroenterology. 94: 1619-26. PMID 10364034 DOI: 10.1111/J.1572-0241.1999.01153.X |
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| 1999 |
Muñoz SJ, Alter HJ, Nakatsuji Y, Shih JW, Reddy RK, Jeffers L, Schiff ER, Reid AE, Marrone A, Rothstein K, Manzarbeitia C, Liang TJ. The Significance of Hepatitis G Virus in Serum of Patients With Sporadic Fulminant and Subfulminant Hepatitis of Unknown Etiology Blood. 94: 1460-1464. DOI: 10.1182/Blood.V94.4.1460 |
0.41 |
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| 1999 |
Reid AE, Koziel MJ, Aiza I, Jeffers L, Reddy R, Schiff E, Lau JYN, Dienstag JL, Liang TJ. Original ContributionsHepatitis c virus genotypes and viremia and hepatocellular carcinoma in the united states The American Journal of Gastroenterology. 94. DOI: 10.1016/S0002-9270(99)00209-9 |
0.472 |
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| 1998 |
Liang TJ. Combination therapy for hepatitis C infection New England Journal of Medicine. 339: 1549-1550. PMID 9819457 DOI: 10.1056/NEJM199811193392112 |
0.35 |
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| 1998 |
Baumert TF, Marrone A, Vergalla J, Liang TJ. Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression Journal of Virology. 72: 6785-6795. PMID 9658127 DOI: 10.1128/Jvi.72.8.6785-6795.1998 |
0.366 |
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| 1998 |
Baumert TF, Ito S, Wong DT, Liang TJ. Hepatitis C Virus Structural Proteins Assemble into Viruslike Particles in Insect Cells Journal of Virology. 72: 3827-3836. PMID 9557666 DOI: 10.1128/Jvi.72.5.3827-3836.1998 |
0.514 |
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| 1997 |
Agnello V, Liang TJ. Is hepatitis C virus a sialodacryoadenitis virus? Hepatology (Baltimore, Md.). 26: 509-10. PMID 9252169 DOI: 10.1002/hep.510260240 |
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| 1997 |
Kawamura T, Furusaka A, Koziel MJ, Chung RT, Wang TC, Schmidt EV, Liang TJ. Transgenic expression of hepatitis C virus structural proteins in the mouse. Hepatology (Baltimore, Md.). 25: 1014-21. PMID 9096613 DOI: 10.1002/hep.510250437 |
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| 1995 |
Reid AE, Liang TJ. Association of hepatitis C virus and hepatocellular carcinoma in the United States. Princess Takamatsu Symposia. 25: 41-9. PMID 8875608 |
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| 1995 |
Bonkovsky HL, Liang TJ, Hasegawa K, Banner B. Chronic leukocytoclastic vasculitis complicating HBV infection. Possible role of mutant forms of HBV in pathogenesis and persistence of disease. Journal of Clinical Gastroenterology. 21: 42-7. PMID 7560833 DOI: 10.1097/00004836-199507000-00011 |
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| 1994 |
Liang TJ, Bodenheimer HC, Yankee R, Brown NV, Chang K, Huang J, Wands JR. Presence of hepatitis B and C viral genomes in US blood donors as detected by polymerase chain reaction amplification. Journal of Medical Virology. 42: 151-7. PMID 8158110 DOI: 10.1002/Jmv.1890420210 |
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| 1994 |
Liang TJ, Anwer MS. Vaccination against hepatitis C virus infection: miles to go before we sleep. Hepatology. 20: 758-760. PMID 8076932 DOI: 10.1002/Hep.1840200329 |
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|
| 1993 |
Liang TJ, Rustgi V, Galun E, Blum HE. HCV RNA in patients with chronic hepatitis C treated with interferon-alpha. Journal of Medical Virology. 40: 69-75. PMID 8390560 DOI: 10.1002/jmv.1890400114 |
0.436 |
|
| 1993 |
Liang TJ, Jeffers LJ, Reddy RK, Silva MO, Cheinquer H, Findor A, Medina MD, Yarbough PO, Reyes GR, Schiff ER. Fulminant or subfulminant non-A, non-B viral hepatitis: The role of hepatitis C and E viruses Gastroenterology. 104: 556-562. PMID 8381099 DOI: 10.1016/0016-5085(93)90426-D |
0.557 |
|
| 1993 |
Liang TJ, Jeffers LJ, Reddy KR, De Medina M, Parker IT, Cheinquer H, Idrovo V, Rabassa A, Schiff ER. Viral pathogenesis of hepatocellular carcinoma in the United States. Hepatology (Baltimore, Md.). 18: 1326-33. PMID 8244256 |
0.39 |
|
| 1993 |
Liang TJ, Jeffers LJ, Reddy KR, Medina MD, Parker IT, Cheinquer H, Idrovo V, Rabassa A, Schiff ER. Viral pathogenesis of hepatocellular carcinoma in the United States. Hepatology. 18: 1326-1333. DOI: 10.1002/Hep.1840180607 |
0.518 |
|
| 1992 |
Wands JR, Liang TJ, Blum HE, Shafritz DA. Molecular pathogenesis of liver disease during persistent hepatitis B virus infection. Seminars in Liver Disease. 12: 252-264. PMID 1439878 DOI: 10.1055/S-2007-1007397 |
0.457 |
|
| 1991 |
Blum HE, Liang TJ, Galun E, Wands JR. Persistence of hepatitis B viral DNA after serological recovery from hepatitis B virus infection Hepatology. 14: 56-63. PMID 2066074 DOI: 10.1002/Hep.1840140110 |
0.481 |
|
| 1991 |
Liang TJ, Hasegawa K, Rimon N, Wands JR, Ben-Porath E. A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis The New England Journal of Medicine. 324: 1705-1709. PMID 2034247 DOI: 10.1056/Nejm199106133242405 |
0.458 |
|
| 1991 |
Hasegawa K, Huang JK, Wands JR, Obata H, Liang TJ. Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan. Virology. 185: 460-3. PMID 1926786 DOI: 10.1016/0042-6822(91)90799-H |
0.419 |
|
| 1991 |
Liang TJ, Baruch Y, Ben-Porath E, Enat R, Bassan L, Brown NV, Rimon N, Blum HE, Wands JR. Hepatitis B virus infection in patients with idiopathic liver disease Hepatology. 13: 1044-1051. DOI: 10.1002/Hep.1840130607 |
0.461 |
|
| 1990 |
Liang TJ, Blum HE, Wands JR. Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serologic markers Hepatology. 12: 204-212. PMID 2167867 DOI: 10.1002/Hep.1840120205 |
0.478 |
|
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