Edward J. Roy, PhD - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
glioma immunotherapy

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ranoa DRE, Sharma P, Schane CP, Lewis AN, Valdez E, Marada VVVR, Hager MV, Montgomery W, Wolf SP, Schreiber K, Schreiber H, Bailey K, Fan TM, Hergenrother PJ, Roy EJ, et al. Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. Journal For Immunotherapy of Cancer. 11. PMID 37258040 DOI: 10.1136/jitc-2022-006509  0.558
2021 Boudreau MW, Duraki D, Wang L, Mao C, Kim JE, Henn MA, Tang B, Fanning SW, Kiefer J, Tarasow TM, Bruckheimer EM, Moreno R, Mousses S, Greene GL, Roy EJ, et al. A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice. Science Translational Medicine. 13. PMID 34290053 DOI: 10.1126/scitranslmed.abf1383  0.535
2020 Tang B, Guo ZS, Bartlett DL, Yan DZ, Schane CP, Liu J, McFadden G, Thomas DL, Shisler JL, Roy EJ. Synergistic Combination of Oncolytic Virotherapy and Immunotherapy for Glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32019860 DOI: 10.1158/1078-0432.Ccr-18-3626  0.602
2020 Duraki D, Boudreau MW, Wang L, Mao C, Tang B, Ma L, Roy EJ, Fan TM, Park BH, Nelson ER, Hergenrother PJ, Shapiro DJ. OR05-05 Lethal ERα-Dependent Hyperactivation of the Unfolded Protein Response Induces Complete Regression Without Recurrence of Primary and Metastatic Breast Cancer Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.653  0.584
2020 Sharma P, Marada VV, Kizerwetter M, Schane CP, He Y, Wolf SP, Schreiber K, Roy EJ, Clausen H, Schreiber H, Kranz DM. Abstract 3238: Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen Immunology. DOI: 10.1158/1538-7445.Am2020-3238  0.33
2019 Tang B, Schane C, Shisler J, Roy E. Abstract A219: Using poxvirus to improve immunotherapy for brain glioma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A219  0.397
2019 Tang B, Guo ZS, Bartlett DL, Yan D, Schane CP, Liu J, McFadden G, Shisler JL, Roy EJ. Abstract 2264: Synergistic combination of oncolytic virotherapy and immunotherapy for glioma Cancer Research. 79: 2264-2264. DOI: 10.1158/1538-7445.Am2019-2264  0.418
2018 Kowalsky SJ, Liu Z, Feist M, Berkey SE, Ma C, Ravindranathan R, Dai E, Roy EJ, Guo ZS, Bartlett DL. Superagonist IL-15-Armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30064894 DOI: 10.1016/j.ymthe.2018.07.013  0.339
2014 Tosic V, Thomas DL, Kranz DM, Liu J, McFadden G, Shisler JL, MacNeill AL, Roy EJ. Myxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor activity. Plos One. 9: e109801. PMID 25329832 DOI: 10.1371/Journal.Pone.0109801  0.588
2014 Stone JD, Harris DT, Soto CM, Chervin AS, Aggen DH, Roy EJ, Kranz DM. A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control. Cancer Immunology, Immunotherapy : Cii. 63: 1163-76. PMID 25082071 DOI: 10.1007/S00262-014-1586-Z  0.406
2013 Chervin AS, Stone JD, Soto CM, Engels B, Schreiber H, Roy EJ, Kranz DM. Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses. Gene Therapy. 20: 634-44. PMID 23052828 DOI: 10.1038/Gt.2012.80  0.41
2013 Soto CM, Stone JD, Chervin AS, Engels B, Schreiber H, Roy EJ, Kranz DM. MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR. Cancer Immunology, Immunotherapy : Cii. 62: 359-69. PMID 22926060 DOI: 10.1007/S00262-012-1336-Z  0.387
2013 Tosic V, Thomas DL, Kranz DM, Liu J, McFadden G, MacNeill AL, Roy EJ. Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P137  0.58
2011 Thomas DL, Doty R, Tosic V, Liu J, Kranz DM, McFadden G, Macneill AL, Roy EJ. Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors. Cancer Immunology, Immunotherapy : Cii. 60: 1461-72. PMID 21656158 DOI: 10.1007/S00262-011-1045-Z  0.614
2011 France MR, Thomas DL, Liu J, McFadden G, MacNeill AL, Roy EJ. Intraventricular injection of myxoma virus results in transient expression of viral protein in mouse brain ependymal and subventricular cells. The Journal of General Virology. 92: 195-9. PMID 20861319 DOI: 10.1099/Vir.0.026690-0  0.547
2009 Meng LJ, Fu G, Roy EJ, Suppe B, Chen CT. An Ultrahigh Resolution SPECT System for I-125 Mouse Brain Imaging Studies. Nuclear Instruments & Methods in Physics Research. Section a, Accelerators, Spectrometers, Detectors and Associated Equipment. 600: 498-505. PMID 20161174 DOI: 10.1016/j.nima.2008.11.149  0.326
2009 Thomas DL, Kim M, Bowerman NA, Narayanan S, Kranz DM, Schreiber H, Roy EJ. Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 1828-37. PMID 19592642 DOI: 10.4049/Jimmunol.0802322  0.616
2009 Roy EJ, Sivaguru M, Fried G, Gray BD, Kranz DM. Imaging membrane intercalating near infrared dyes to track multiple cell populations. Journal of Immunological Methods. 348: 18-29. PMID 19559026 DOI: 10.1016/J.Jim.2009.06.006  0.325
2008 Fan TM, Kranz DM, Flavell RA, Roy EJ. Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8+ regulatory T cells. Molecular Immunology. 45: 2937-50. PMID 18321576 DOI: 10.1016/J.Molimm.2008.01.019  0.575
2008 Thomas DL, Kranz DM, Roy EJ. Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors. Cancer Immunology, Immunotherapy : Cii. 57: 1323-33. PMID 18278494 DOI: 10.1007/S00262-008-0467-8  0.602
2007 Fan TM, Kranz DM, Roy EJ. Enhancing antitumor immunity: combining IL-12 with TGFbeta1 antagonism. Journal of Immunotherapy (Hagerstown, Md. : 1997). 30: 479-89. PMID 17589288 DOI: 10.1097/Cji.0B013E318031A2B2  0.57
2005 Roy EJ, Takikawa O, Kranz DM, Brown AR, Thomas DL. Neuronal localization of indoleamine 2,3-dioxygenase in mice. Neuroscience Letters. 387: 95-9. PMID 16076525 DOI: 10.1016/J.Neulet.2005.07.010  0.51
2004 Gawlick U, Kranz DM, Schepkin VD, Roy EJ. A conjugate of a tumor-targeting ligand and a T cell costimulatory antibody to treat brain tumors. Bioconjugate Chemistry. 15: 1137-45. PMID 15366970 DOI: 10.1021/Bc049911E  0.784
2004 Roy EJ, Gawlick U, Orr BA, Kranz DM. Folate-mediated targeting of T cells to tumors. Advanced Drug Delivery Reviews. 56: 1219-31. PMID 15094217 DOI: 10.1016/J.Addr.2004.01.006  0.765
2003 Orr BA, Carr LM, Wittrup KD, Roy EJ, Kranz DM. Rapid method for measuring ScFv thermal stability by yeast surface display. Biotechnology Progress. 19: 631-8. PMID 12675608 DOI: 10.1021/Bp0200797  0.493
2000 Roy EJ, Gawlick U, Orr BA, Rund LA, Webb AG, Kranz DM. IL-12 treatment of endogenously arising murine brain tumors. Journal of Immunology (Baltimore, Md. : 1950). 165: 7293-9. PMID 11120864 DOI: 10.4049/Jimmunol.165.12.7293  0.768
1999 Rund LA, Cho BK, Manning TC, Holler PD, Roy EJ, Kranz DM. Bispecific agents target endogenous murine T cells against human tumor xenografts. International Journal of Cancer. Journal International Du Cancer. 83: 141-9. PMID 10449621 DOI: 10.1002/(Sici)1097-0215(19990924)83:1<141::Aid-Ijc24>3.0.Co;2-0  0.405
1998 Patrick TA, Kranz DM, Zachary JF, Roy EJ. Intracerebral bispecific ligand-antibody conjugate increases survival of animals bearing endogenously arising brain tumors. International Journal of Cancer. Journal International Du Cancer. 78: 470-9. PMID 9797136 DOI: 10.1002/(Sici)1097-0215(19981109)78:4<470::Aid-Ijc13>3.0.Co;2-A  0.404
1998 Kranz DM, Manning TC, Rund LA, Cho BK, Gruber MM, Roy EJ. Targeting tumor cells with bispecific antibodies and T cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 53: 77-84. PMID 9741915 DOI: 10.1016/S0168-3659(97)00239-3  0.425
1998 Roy EJ, Cho BK, Rund LA, Patrick TA, Kranz DM. Targeting T cells against brain tumors with a bispecific ligand-antibody conjugate. International Journal of Cancer. Journal International Du Cancer. 76: 761-6. PMID 9610737 DOI: 10.1002/(Sici)1097-0215(19980529)76:5<761::Aid-Ijc23>3.0.Co;2-5  0.424
1997 Conrad CD, Leone D, Nemivant RR, Roy EJ. Long-term adrenalectomy can decrease or increase hippocampal dentate gyrus volumes. Journal of Neuroendocrinology. 9: 355-61. PMID 9181489 DOI: 10.1046/J.1365-2826.1997.00584.X  0.734
1997 Cho BK, Roy EJ, Patrick TA, Kranz DM. Single-chain Fv/folate conjugates mediate efficient lysis of folate-receptor-positive tumor cells. Bioconjugate Chemistry. 8: 338-46. PMID 9177839 DOI: 10.1021/Bc9700244  0.402
1997 Patrick TA, Kranz DM, van Dyke TA, Roy EJ. Folate receptors as potential therapeutic targets in choroid plexus tumors of SV40 transgenic mice. Journal of Neuro-Oncology. 32: 111-23. PMID 9120540 DOI: 10.1023/A:1005713115147  0.382
1995 Conrad CD, Roy EJ. Dentate gyrus destruction and spatial learning impairment after corticosteroid removal in young and middle-aged rats. Hippocampus. 5: 1-15. PMID 7787942 DOI: 10.1002/hipo.450050103  0.728
1995 Kranz DM, Patrick TA, Brigle KE, Spinella MJ, Roy EJ. Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate-receptor-positive tumor cells for lysis. Proceedings of the National Academy of Sciences of the United States of America. 92: 9057-61. PMID 7568072 DOI: 10.1073/Pnas.92.20.9057  0.386
1993 Dwyer KD, Roy EJ. Juvenile desipramine reduces adult sensitivity to imipramine in two behavioral tests. Pharmacology, Biochemistry, and Behavior. 45: 201-7. PMID 8516359 DOI: 10.1016/0091-3057(93)90105-3  0.303
1993 Conrad CD, Roy EJ. Selective loss of hippocampal granule cells following adrenalectomy: implications for spatial memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2582-90. PMID 8501524 DOI: 10.1523/Jneurosci.13-06-02582.1993  0.715
1991 Montemayor ME, Giometti CS, Taylor J, Roy EJ. Progesterone-dependent sexual behavior and protein patterns in the ventromedial hypothalamus of the adult female rat. Molecular and Cellular Neurosciences. 2: 491-500. PMID 19912834 DOI: 10.1016/1044-7431(91)90016-H  0.322
1990 Roy EJ, Buyer DR, Licari VA. Estradiol in the striatum: effects on behavior and dopamine receptors but no evidence for membrane steroid receptors. Brain Research Bulletin. 25: 221-7. PMID 2224537 DOI: 10.1016/0361-9230(90)90064-7  0.328
1990 Montemayor ME, Clark AS, Lynn DM, Roy EJ. Modulation by norepinephrine of neural responses to estradiol. Neuroendocrinology. 52: 473-80. PMID 2177855 DOI: 10.1159/000125631  0.609
1990 Roy EJ, Lynn DM, Bemm CW. Individual variations in hippocampal dentate degeneration following adrenalectomy. Behavioral and Neural Biology. 54: 330-6. PMID 2078164 DOI: 10.1016/0163-1047(90)90672-S  0.349
1989 Wilson MA, Dwyer KD, Roy EJ. Direct effects of ovarian hormones on antidepressant binding sites. Brain Research Bulletin. 22: 181-5. PMID 2706532 DOI: 10.1016/0361-9230(89)90040-3  0.487
1989 Cohen-Parsons M, Roy EJ. Social stimuli augment estrogen receptor binding in preoptic area of female prairie voles. Brain Research. 476: 363-6. PMID 2649206 DOI: 10.1016/0006-8993(89)91260-2  0.34
1988 Clemens LG, Wee BE, Weaver DR, Roy EJ, Goldman BD, Rakerd B. Retention of masculine sexual behavior following castration in male B6D2F1 mice. Physiology & Behavior. 42: 69-76. PMID 3387479 DOI: 10.1016/0031-9384(88)90262-4  0.306
1987 Yongue BG, Roy EJ. Endogenous aldosterone and corticosterone in brain cell nuclei of adrenal-intact rats: regional distribution and effects of physiological variations in serum steroids. Brain Research. 436: 49-61. PMID 3690353 DOI: 10.1016/0006-8993(87)91555-1  0.392
1987 Roy EJ, Lynn DM. Asymmetry in responsiveness of the hypothalamus of the female rat to estradiol. Physiology & Behavior. 40: 267-9. PMID 3628537 DOI: 10.1016/0031-9384(87)90219-8  0.333
1987 Clark AS, Roy EJ. Effective intervals for the administration of estradiol pulses and the induction of sexual behavior in female rats. Physiology & Behavior. 39: 665-7. PMID 3588717 DOI: 10.1016/0031-9384(87)90171-5  0.561
1986 Wilson MA, Roy EJ. Pharmacokinetics of imipramine are affected by age and sex in rats. Life Sciences. 38: 711-8. PMID 3951327 DOI: 10.1016/0024-3205(86)90585-0  0.521
1986 Roy EJ, Wilson MA, Kelley DB. Estrogen-induced progestin receptors in the brain and pituitary of the South African clawed frog, Xenopus laevis. Neuroendocrinology. 42: 51-6. PMID 3941759 DOI: 10.1159/000124248  0.544
1986 MacLusky NJ, Roy EJ, Shanabrough M, Eisenfeld AJ. Preservation of steroid receptors in frozen brain and pituitary tissue: use of the cryoprotective agent, dimethylsulfoxide. Journal of Neuroscience Methods. 16: 131-40. PMID 3724229 DOI: 10.1016/0165-0270(86)90045-2  0.361
1985 Clark AS, Roy EJ. Behavioral insensitivity to progesterone during lactation in female rats. Physiology & Behavior. 34: 677-82. PMID 4041053 DOI: 10.1016/0031-9384(85)90363-4  0.6
1985 Clark AS, Davis LA, Roy EJ. A possible physiological basis for the dud-stud phenomenon. Hormones and Behavior. 19: 227-30. PMID 4007800 DOI: 10.1016/0018-506X(85)90022-4  0.574
1985 Roy EJ, Lynn DM, Clark AS. Inhibition of sexual receptivity by anesthesia during estrogen priming. Brain Research. 337: 163-6. PMID 4005605 DOI: 10.1016/0006-8993(85)91624-5  0.573
1985 Yongue BG, Roy EJ. Adrenalectomy fails to alter radial maze performance of rats at retention intervals of 24 hours or less. Physiology & Behavior. 35: 651-4. PMID 2999847 DOI: 10.1016/0031-9384(85)90157-X  0.341
1985 Clark AS, Nock B, Feder HH, Roy EJ. Alpha 1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area. Brain Research. 330: 197-9. PMID 2985191 DOI: 10.1016/0006-8993(85)90028-9  0.654
1984 Wilson MA, Roy EJ. Age alters the observed response of imipramine binding sites to chronic antidepressant treatment in female rats. European Journal of Pharmacology. 106: 381-91. PMID 6099275 DOI: 10.1016/0014-2999(84)90726-X  0.495
1983 Clark AS, Roy EJ. Behavioral and cellular responses to pulses of low doses of estradiol-17 beta. Physiology & Behavior. 30: 561-5. PMID 6878455 DOI: 10.1016/0031-9384(83)90221-4  0.564
1983 Wilson MA, Clark AS, Clyde V, Roy EJ. Characterization of a pineal-independent diurnal rhythm in neural estrogen receptors and its possible behavioral consequences. Neuroendocrinology. 37: 14-22. PMID 6684216 DOI: 10.1159/000123510  0.666
1982 Roy EJ, Sheinkop S, Wilson MA. Age alters dopaminergic responses to estradiol. European Journal of Pharmacology. 82: 73-5. PMID 6889971 DOI: 10.1016/0014-2999(82)90554-4  0.494
1981 Jellinck PH, Krey L, Davis PG, Kamel F, Luine V, Parsons B, Roy EJ, McEwen BS. Central and peripheral action of estradiol and catecholestrogens administered at low concentration by constant infusion. Endocrinology. 108: 1848-54. PMID 7215303 DOI: 10.1210/endo-108-5-1848  0.646
1981 Roy EJ, Wilson MA. Diurnal rhythm of cytoplasmic estrogen receptors in the rat brain in the absence of circulating estrogens. Science (New York, N.Y.). 213: 1525-7. PMID 7197053 DOI: 10.1126/Science.7197053  0.54
1980 McEwen BS, Davis PG, Jellinck PH, Krey LC, Lieberburg I, Luine VN, MacLusky NJ, Parsons B, Roy EJ. Steroid hormone receptors, brain cell function, and the neuroendocrine system. Advances in Biochemical Psychopharmacology. 21: 383-90. PMID 7376972  0.554
1979 McEwen BS, Lieberburg I, Chaptal C, Davis PG, Krey LC, MacLusky NJ, Roy EJ. Attenuating the defeminization of the neonatal rat brain: mechanisms of action of cyproterone acetate, 1,4,6-androstatriene-3,17,-dione and a synthetic progestin, R5020. Hormones and Behavior. 13: 269-81. PMID 575953 DOI: 10.1016/0018-506X(79)90044-8  0.535
1979 Krey LC, Lieberburg I, Roy E, McEwen BS. Oestradiol plus receptor complexes in the brain and anterior pituitary gland: quantitation and neuroendocrine significance. Journal of Steroid Biochemistry. 11: 279-84. PMID 491597 DOI: 10.1016/0022-4731(79)90309-1  0.515
1979 Blaustein JD, Dudley SD, Gray JM, Roy EJ, Wade GN. Long-term retention of estradiol by brain cell nuclei and female rat sexual behavior. Brain Research. 173: 355-9. PMID 487097 DOI: 10.1016/0006-8993(79)90637-1  0.637
1979 Roy EJ, McEwen BS. Oestrogen receptors in cell nuclei of the hypothalamus-preoptic area-amygdala following an injection of oestradiol or the antioestrogen CI-628. The Journal of Endocrinology. 83: 285-93. PMID 395264 DOI: 10.1677/joe.0.0830285  0.5
1979 Roy EJ, MacLusky NJ, McEwen BS. Antiestrogen inhibits the induction of progestin receptors by estradiol in the hypothalamus-preoptic area and pituitary. Endocrinology. 104: 1333-6. PMID 220031 DOI: 10.1210/endo-104-5-1333  0.519
1978 Lieberburg I, Maclusky NJ, Roy EJ, Mcewen BS. Sex steroid receptors in the perinatal rat brain Integrative and Comparative Biology. 18: 539-544. DOI: 10.1093/icb/18.3.539  0.582
1977 Roy EJ, Maass CA, Wade GN. Central action and a species comparison of the estrogenic effects of an antiestrogen on eating and body weight. Physiology & Behavior. 18: 137-40. PMID 905369 DOI: 10.1016/0031-9384(77)90105-6  0.403
1977 Roy EJ, Wade GN. Role of food intake in estradiol-induced body weight changes in female rats. Hormones and Behavior. 8: 265-74. PMID 881167 DOI: 10.1016/0018-506X(77)90001-0  0.435
1977 Roy EJ, Wade GN. Binding of [3-H]estradiol by brain cell nuclei and female rat sexual behavior: inhibition by antiestrogens. Brain Research. 126: 73-87. PMID 856418 DOI: 10.1016/0006-8993(77)90216-5  0.471
1977 Roy EJ, McEwen BS. An exchange assay for estrogen receptors in cell nuclei of the adult rat brain. Steroids. 30: 657-69. PMID 611633 DOI: 10.1016/0039-128X(77)90055-1  0.503
1976 Blaustein JD, Gentry RT, Roy EJ, Wade GN. Effects of ovariectomy and estradiol on body weight and food intake in gold thioglucose-treated mice. Physiology & Behavior. 17: 1027-30. PMID 14677602 DOI: 10.1016/0031-9384(76)90028-7  0.58
1976 Gentry RT, Wade GN, Roy EJ. Individual differences in estradiol-induced behaviors and in neural 3H-estradiol uptake in rats. Physiology & Behavior. 17: 195-200. PMID 996156 DOI: 10.1016/0031-9384(76)90063-9  0.455
1975 Marrone BL, Roy EJ, Wade GN. Progesterone stimulates running wheel activity in adrenalectomized-ovariectomized rats. Hormones and Behavior. 6: 231-6. PMID 1221012 DOI: 10.1016/0018-506X(75)90010-0  0.459
1975 Roy EJ, Wade GN. Role of estrogens in androgen-induced spontaneous activity in male rats. Journal of Comparative and Physiological Psychology. 89: 573-9. PMID 1194459 DOI: 10.1037/h0077436  0.556
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