Sangeeta N. Bhatia - Publications

Affiliations: 
Biomedical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 March S, Nerurkar N, Jain A, Andrus L, Kim D, Whittaker CA, Tan EKW, Thiberge S, Fleming HE, Mancio-Silva L, Rice CM, Bhatia SN. Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses. Science Advances. 10: eadm9281. PMID 38657074 DOI: 10.1126/sciadv.adm9281  0.749
2022 Mancio-Silva L, Gural N, Real E, Wadsworth MH, Butty VL, March S, Nerurkar N, Hughes TK, Roobsoong W, Fleming HE, Whittaker CA, Levine SS, Sattabongkot J, Shalek AK, Bhatia SN. A single-cell liver atlas of Plasmodium vivax infection. Cell Host & Microbe. PMID 35443155 DOI: 10.1016/j.chom.2022.03.034  0.744
2020 Chen AX, Chhabra A, Song HG, Fleming HE, Chen CS, Bhatia SN. Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. Advanced Functional Materials. 30. PMID 33776613 DOI: 10.1002/Adfm.201910442  0.657
2020 Song HG, Lammers A, Sundaram S, Rubio L, Chen AX, Li L, Eyckmans J, Bhatia SN, Chen CS. Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. Advanced Functional Materials. 30. PMID 33613149 DOI: 10.1002/Adfm.202003777  0.63
2020 Tian C, Öhlund D, Rickelt S, Lidström T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Research. PMID 32029550 DOI: 10.1158/0008-5472.Can-19-2578  0.318
2020 Michailidis E, Vercauteren K, Mancio-Silva L, Andrus L, Jahan C, Ricardo-Lax I, Zou C, Kabbani M, Park P, Quirk C, Pyrgaki C, Razooky B, Verhoye L, Zoluthkin I, Lu WY, ... ... Bhatia SN, et al. Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31915293 DOI: 10.1073/Pnas.1919035117  0.366
2020 Vo TN, Chen AX, Smith QB, Chhabra A, Bhatia SN. Integrated Technologies for Liver Tissue Engineering Liver. 1028-1035. DOI: 10.1002/9781119436812.Ch79  0.609
2019 Vera IM, Grilo Ruivo MT, Lemos Rocha LF, Marques S, Bhatia SN, Mota MM, Mancio-Silva L. Targeting liver stage malaria with metformin. Jci Insight. 4. PMID 31852843 DOI: 10.1172/Jci.Insight.127441  0.326
2019 Jain PK, Lo JH, Rananaware S, Downing M, Panda A, Tai M, Raghavan S, Fleming HE, Bhatia SN. Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes. Nanoscale. PMID 31670340 DOI: 10.1039/C9Nr01786K  0.503
2019 Camarda G, Jirawatcharadech P, Priestley RS, Saif A, March S, Wong MHL, Leung S, Miller AB, Baker DA, Alano P, Paine MJI, Bhatia SN, O'Neill PM, Ward SA, Biagini GA. Antimalarial activity of primaquine operates via a two-step biochemical relay. Nature Communications. 10: 3226. PMID 31324806 DOI: 10.1038/S41467-019-11239-0  0.324
2019 Mancio-Silva L, Fleming HE, Miller AB, Milstein S, Liebow A, Haslett P, Sepp-Lorenzino L, Bhatia SN. Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers. Cell Metabolism. 29: 727-735.e3. PMID 30840913 DOI: 10.1016/J.Cmet.2019.02.003  0.38
2019 Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Aravena M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, et al. Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. PMID 30641053 DOI: 10.1053/J.Gastro.2019.01.010  0.323
2018 Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, et al. Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. Hepatology Communications. 2: 786-797. PMID 30202815 DOI: 10.1002/hep4.1179  0.699
2018 Lo JH, Hao L, Muzumdar MD, Raghavan S, Kwon EJ, Pulver EM, Hsu F, Aguirre AJ, Wolpin BM, Fuchs CS, Hahn WC, Jacks T, Bhatia SN. iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer. Molecular Cancer Therapeutics. PMID 30097486 DOI: 10.1158/1535-7163.Mct-17-1090  0.304
2018 Gural N, Mancio-Silva L, Miller AB, Galstian A, Butty VL, Levine SS, Patrapuvich R, Desai SP, Mikolajczak SA, Kappe SHI, Fleming HE, March S, Sattabongkot J, Bhatia SN. In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites. Cell Host & Microbe. PMID 29478773 DOI: 10.1016/J.Chom.2018.01.002  0.348
2018 Gural N, Mancio-Silva L, He J, Bhatia SN. Engineered Livers for Infectious Diseases. Cellular and Molecular Gastroenterology and Hepatology. 5: 131-144. PMID 29322086 DOI: 10.1016/J.Jcmgh.2017.11.005  0.394
2017 Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE. Depolarization signatures map gold nanorods within biological tissue. Nature Photonics. 11: 583-588. PMID 29201136 DOI: 10.1038/Nphoton.2017.128  0.306
2017 Michailidis E, Pabon J, Xiang K, Park P, Ramanan V, Hoffmann HH, Schneider WM, Bhatia SN, de Jong YP, Shlomai A, Rice CM. A robust cell culture system supporting the complete life cycle of hepatitis B virus. Scientific Reports. 7: 16616. PMID 29192196 DOI: 10.1038/S41598-017-16882-5  0.316
2017 Ren Y, Sagers JE, Landegger LD, Bhatia SN, Stankovic KM. Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas. Scientific Reports. 7: 12922. PMID 29018206 DOI: 10.1038/S41598-017-13032-9  0.315
2017 Kwon EJ, Dudani JS, Bhatia SN. Ultrasensitive tumour-penetrating nanosensors of protease activity. Nature Biomedical Engineering. 1. PMID 28970963 DOI: 10.1038/S41551-017-0054  0.309
2017 Stevens KR, Scull MA, Ramanan V, Fortin CL, Chaturvedi RR, Knouse KA, Xiao JW, Fung C, Mirabella T, Chen AX, McCue MG, Yang MT, Fleming HE, Chung K, de Jong YP, ... ... Bhatia SN, et al. In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease. Science Translational Medicine. 9. PMID 28724577 DOI: 10.1126/Scitranslmed.Aah5505  0.653
2017 Ng S, March S, Galstian A, Gural N, Stevens KR, Mota MM, Bhatia SN. Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers. Scientific Reports. 7: 45424. PMID 28361899 DOI: 10.1038/Srep45424  0.368
2017 Hao L, Lo J, Bhatia S. Abstract 5088: Tumor penetrating RNA delivery for therapeutic benefit of pancreatic cancer Cancer Research. 77: 5088-5088. DOI: 10.1158/1538-7445.Am2017-5088  0.305
2016 Shan J, Logan DJ, Root DE, Carpenter AE, Bhatia SN. High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro. Journal of Biomolecular Screening. 21: 897-911. PMID 27650791 DOI: 10.1177/1087057116660277  0.404
2016 Schuerle S, Dudani JS, Christiansen MG, Anikeeva P, Bhatia SN. Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling. Nano Letters. PMID 27622711 DOI: 10.1021/Acs.Nanolett.6B02670  0.307
2016 Ruivo MT, Vera IM, Sales-Dias J, Meireles P, Gural N, Bhatia SN, Mota MM, Mancio-Silva L. Host AMPK Is a Modulator of Plasmodium Liver Infection. Cell Reports. PMID 27568570 DOI: 10.1016/J.Celrep.2016.08.001  0.316
2016 Jain PK, Ramanan V, Schepers AG, Dalvie NS, Panda A, Fleming HE, Bhatia SN. Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors. Angewandte Chemie (International Ed. in English). PMID 27554600 DOI: 10.1002/Anie.201606123  0.471
2016 Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, ... ... Bhatia S, et al. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. Plos Pathogens. 12: e1005763. PMID 27467575 DOI: 10.1371/Journal.Ppat.1005763  0.31
2016 Din MO, Danino T, Prindle A, Skalak M, Selimkhanov J, Allen K, Julio E, Atolia E, Tsimring LS, Bhatia SN, Hasty J. Synchronized cycles of bacterial lysis for in vivo delivery. Nature. PMID 27437587 DOI: 10.1038/Nature18930  0.32
2016 Schepers A, Li C, Chhabra A, Seney BT, Bhatia S. Engineering a perfusable 3D human liver platform from iPS cells. Lab On a Chip. PMID 27296616 DOI: 10.1039/C6Lc00598E  0.446
2016 Braga Malta DF, Reticker-Flynn NE, da Silva CL, Cabral JM, Fleming HE, Zaret KS, Bhatia SN, Underhill GH. Extracellular matrix microarrays to study inductive signaling for endoderm specification. Acta Biomaterialia. 34: 30-40. PMID 26883775 DOI: 10.1016/J.Actbio.2016.02.014  0.71
2015 Logan DJ, Shan J, Bhatia SN, Carpenter AE. Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification. Methods (San Diego, Calif.). PMID 26687239 DOI: 10.1016/J.Ymeth.2015.12.002  0.354
2015 March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, Scull MA, Shlomai A, Mota MM, Fleming HE, Khetani SR, Rice CM, Bhatia SN. Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. Nature Protocols. 10: 2027-2053. PMID 26584444 DOI: 10.1038/Nprot.2015.128  0.388
2015 Dudani JS, Jain PK, Kwong GA, Stevens KR, Bhatia SN. Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity. Acs Nano. PMID 26565752 DOI: 10.1021/Acsnano.5B05946  0.5
2015 Phillips MA, Lotharius J, Marsh K, White J, Dayan A, White KL, Njoroge JW, El Mazouni F, Lao Y, Kokkonda S, Tomchick DR, Deng X, Laird T, Bhatia SN, March S, et al. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Science Translational Medicine. 7: 296ra111. PMID 26180101 DOI: 10.1126/Scitranslmed.Aaa6645  0.303
2015 Danino T, Prindle A, Kwong GA, Skalak M, Li H, Allen K, Hasty J, Bhatia SN. Programmable probiotics for detection of cancer in urine. Science Translational Medicine. 7: 289ra84. PMID 26019220 DOI: 10.1126/Scitranslmed.Aaa3519  0.395
2015 Stevens KR, Miller JS, Blakely BL, Chen CS, Bhatia SN. Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering. Journal of Biomedical Materials Research. Part A. PMID 25851120 DOI: 10.1002/Jbm.A.35478  0.374
2015 Ng S, Schwartz RE, March S, Galstian A, Gural N, Shan J, Prabhu M, Mota MM, Bhatia SN. Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro. Stem Cell Reports. 4: 348-59. PMID 25660406 DOI: 10.1016/J.Stemcr.2015.01.002  0.348
2015 Reticker-Flynn NE, Bhatia SN. Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche. Cancer Discovery. 5: 168-81. PMID 25421439 DOI: 10.1158/2159-8290.Cd-13-0760  0.312
2015 Hanson KK, March S, Ng S, Bhatia SN, Mota MM. In vitro alterations do not reflect a requirement for host cell cycle progression during Plasmodium liver stage infection. Eukaryotic Cell. 14: 96-103. PMID 25416236 DOI: 10.1128/Ec.00166-14  0.391
2015 Chaturvedi RR, Stevens KR, Solorzano RD, Schwartz RE, Eyckmans J, Baranski JD, Stapleton SC, Bhatia SN, Chen CS. Patterning vascular networks in vivo for tissue engineering applications. Tissue Engineering. Part C, Methods. 21: 509-17. PMID 25390971 DOI: 10.1089/Ten.Tec.2014.0258  0.353
2014 Hui EE, Li C, Agrawal A, Bhatia SN. A Macro-to-Micro Interface for the Control of Cellular Organization. Journal of Microelectromechanical Systems : a Joint Ieee and Asme Publication On Microstructures, Microactuators, Microsensors, and Microsystems. 23: 391-397. PMID 26167106 DOI: 10.1109/Jmems.2013.2278813  0.662
2014 Ramanan V, Scull MA, Sheahan TP, Rice CM, Bhatia SN. New Methods in Tissue Engineering: Improved Models for Viral Infection. Annual Review of Virology. 1: 475-499. PMID 25893203 DOI: 10.1146/Annurev-Virology-031413-085437  0.343
2014 Bhatia SN, Ingber DE. Microfluidic organs-on-chips. Nature Biotechnology. 32: 760-72. PMID 25093883 DOI: 10.1038/Nbt.2989  0.369
2014 Shlomai A, Schwartz RE, Ramanan V, Bhatta A, de Jong YP, Bhatia SN, Rice CM. Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Proceedings of the National Academy of Sciences of the United States of America. 111: 12193-8. PMID 25092305 DOI: 10.1073/Pnas.1412631111  0.349
2014 Bhatia SN, Underhill GH, Zaret KS, Fox IJ. Cell and tissue engineering for liver disease. Science Translational Medicine. 6: 245sr2. PMID 25031271 DOI: 10.1126/Scitranslmed.3005975  0.716
2014 Li CY, Stevens KR, Schwartz RE, Alejandro BS, Huang JH, Bhatia SN. Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. Tissue Engineering. Part A. 20: 2200-12. PMID 24498910 DOI: 10.1089/Ten.Tea.2013.0667  0.414
2014 Schwartz RE, Fleming HE, Khetani SR, Bhatia SN. Pluripotent stem cell-derived hepatocyte-like cells. Biotechnology Advances. 32: 504-13. PMID 24440487 DOI: 10.1016/J.Biotechadv.2014.01.003  0.423
2014 Ng S, March S, Galstian A, Hanson K, Carvalho T, Mota MM, Bhatia SN. Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro. Disease Models & Mechanisms. 7: 215-24. PMID 24291761 DOI: 10.1242/Dmm.013490  0.391
2014 Schwartz RE, Shan J, Duncan SA, Goessling W, Bhatia S. 762 Control of Microenvironmental Cues Enables the Differentiation of Pluripotent Stem Cell Derived Hepatocyte-Like Cells to an Adult Phenotype Gastroenterology. 146: S-926. DOI: 10.1016/S0016-5085(14)63363-1  0.338
2013 Hauert S, Berman S, Nagpal R, Bhatia SN. A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors. Nano Today. 8: 566-576. PMID 25009578 DOI: 10.1016/J.Nantod.2013.11.001  0.305
2013 Vunjak-Novakovic G, Bhatia S, Chen C, Hirschi K. HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. Stem Cell Research & Therapy. 4: S8. PMID 24565063 DOI: 10.1186/Scrt369  0.372
2013 Wong IY, Bhatia SN, Toner M. Nanotechnology: emerging tools for biology and medicine. Genes & Development. 27: 2397-408. PMID 24240230 DOI: 10.1101/Gad.226837.113  0.472
2013 March S, Ng S, Velmurugan S, Galstian A, Shan J, Logan DJ, Carpenter AE, Thomas D, Sim BK, Mota MM, Hoffman SL, Bhatia SN. A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host & Microbe. 14: 104-15. PMID 23870318 DOI: 10.1016/J.Chom.2013.06.005  0.353
2013 Shan J, Schwartz RE, Ross NT, Logan DJ, Thomas D, Duncan SA, North TE, Goessling W, Carpenter AE, Bhatia SN. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nature Chemical Biology. 9: 514-20. PMID 23728495 DOI: 10.1038/Nchembio.1270  0.379
2013 Stevens KR, Ungrin MD, Schwartz RE, Ng S, Carvalho B, Christine KS, Chaturvedi RR, Li CY, Zandstra PW, Chen CS, Bhatia SN. InVERT molding for scalable control of tissue microarchitecture. Nature Communications. 4: 1847. PMID 23673632 DOI: 10.1038/Ncomms2853  0.402
2013 Desai SP, Bhatia SN, Toner M, Irimia D. Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophysical Journal. 104: 2077-88. PMID 23663851 DOI: 10.1016/J.Bpj.2013.03.025  0.487
2013 Baranski JD, Chaturvedi RR, Stevens KR, Eyckmans J, Carvalho B, Solorzano RD, Yang MT, Miller JS, Bhatia SN, Chen CS. Geometric control of vascular networks to enhance engineered tissue integration and function. Proceedings of the National Academy of Sciences of the United States of America. 110: 7586-91. PMID 23610423 DOI: 10.1073/Pnas.1217796110  0.342
2013 Li CY, Wood DK, Huang JH, Bhatia SN. Flow-based pipeline for systematic modulation and analysis of 3D tumor microenvironments. Lab On a Chip. 13: 1969-78. PMID 23563587 DOI: 10.1039/C3Lc41300D  0.362
2013 Kwong GA, von Maltzahn G, Murugappan G, Abudayyeh O, Mo S, Papayannopoulos IA, Sverdlov DY, Liu SB, Warren AD, Popov Y, Schuppan D, Bhatia SN. Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease. Nature Biotechnology. 31: 63-70. PMID 23242163 DOI: 10.1038/Nbt.2464  0.322
2013 Schwartz RE, Shan J, Duncan SA, Goessling W, Bhatia S. Mo1784 Engineering the Microenvironment of Differentiating IPS Derived Hepatocyte-Like Cells Enables Acquisition of an Adult Phenotype Gastroenterology. 144: S-1025. DOI: 10.1016/S0016-5085(13)63811-1  0.329
2012 Underhill GH, Galie P, Chen CS, Bhatia SN. Bioengineering methods for analysis of cells in vitro. Annual Review of Cell and Developmental Biology. 28: 385-410. PMID 23057744 DOI: 10.1146/Annurev-Cellbio-101011-155709  0.701
2012 Reticker-Flynn NE, Malta DF, Winslow MM, Lamar JM, Xu MJ, Underhill GH, Hynes RO, Jacks TE, Bhatia SN. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nature Communications. 3: 1122. PMID 23047680 DOI: 10.1038/Ncomms2128  0.677
2012 El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proceedings of the National Academy of Sciences of the United States of America. 109: 17460-5. PMID 23033492 DOI: 10.1073/Pnas.1206653109  0.495
2012 Ren Y, Hauert S, Lo JH, Bhatia SN. Identification and characterization of receptor-specific peptides for siRNA delivery. Acs Nano. 6: 8620-31. PMID 22909216 DOI: 10.1021/Nn301975S  0.323
2012 Miller JS, Stevens KR, Yang MT, Baker BM, Nguyen DH, Cohen DM, Toro E, Chen AA, Galie PA, Yu X, Chaturvedi R, Bhatia SN, Chen CS. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nature Materials. 11: 768-74. PMID 22751181 DOI: 10.1038/Nmat3357  0.338
2012 Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN. A biophysical indicator of vaso-occlusive risk in sickle cell disease. Science Translational Medicine. 4: 123ra26. PMID 22378926 DOI: 10.1126/Scitranslmed.3002738  0.312
2012 Schwartz RE, Trehan K, Andrus L, Sheahan TP, Ploss A, Duncan SA, Rice CM, Bhatia SN. Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2544-8. PMID 22308485 DOI: 10.1073/Pnas.1121400109  0.351
2012 Bhatia SN, Yarmush ML, Toner M. Micropatterning cells in tissue engineering. Methods in Molecular Medicine. 18: 349-63. PMID 21370189 DOI: 10.1385/0-89603-516-6:349  0.651
2012 Rotem A, Toner M, Bhatia S, Foy BD, Tompkins RG, Yarmush ML. Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes. Biotechnology and Bioengineering. 43: 654-60. PMID 18615765 DOI: 10.1002/Bit.260430715  0.607
2012 Reticker-Flynn NE, Malta DFB, Winslow MM, Xu MJ, Lamar JM, Hynes RO, Jacks TE, Bhatia SN. Abstract 2973: Adhesion of tumor cells to ECM microarrays identifies novel ECM interactions in metastasis Cancer Research. 72: 2973-2973. DOI: 10.1158/1538-7445.Am2012-2973  0.347
2012 Schwartz R, Trehan K, Andrus L, Sheahan T, Ploss A, Duncan SA, Rice C, Bhatia S. Su1581 Modeling Hepatitis C Virus Infection Using Human Induced Pluripotent Stem Cells Gastroenterology. 142: S-971. DOI: 10.1016/S0016-5085(12)63761-5  0.306
2012 Bhatia S. Engineering Cooperative Nanosytems Biophysical Journal. 102: 598a-599a. DOI: 10.1016/J.Bpj.2011.11.3259  0.305
2011 Li CY, Wood DK, Hsu CM, Bhatia SN. DNA-templated assembly of droplet-derived PEG microtissues. Lab On a Chip. 11: 2967-75. PMID 21776518 DOI: 10.1039/C1Lc20318E  0.344
2011 Chen AA, Thomas DK, Ong LL, Schwartz RE, Golub TR, Bhatia SN. Humanized mice with ectopic artificial liver tissues. Proceedings of the National Academy of Sciences of the United States of America. 108: 11842-7. PMID 21746904 DOI: 10.1073/Pnas.1101791108  0.372
2011 Danino T, Volfson D, Bhatia SN, Tsimring L, Hasty J. In-silico patterning of vascular mesenchymal cells in three dimensions. Plos One. 6: e20182. PMID 21633504 DOI: 10.1371/Journal.Pone.0020182  0.342
2011 Goldberg MS, Xing D, Ren Y, Orsulic S, Bhatia SN, Sharp PA. Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 745-50. PMID 21187397 DOI: 10.1073/Pnas.1016538108  0.314
2011 Schwartz R, Bhatia S. Human IPS Cells Differentiate Into Hepatocyte-Like Cells With the Phenotypic and Functional Characteristics of Hepatocytes Gastroenterology. 140: S-978. DOI: 10.1016/S0016-5085(11)64052-3  0.377
2010 Chen AA, Underhill GH, Bhatia SN. Multiplexed, high-throughput analysis of 3D microtissue suspensions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2: 517-27. PMID 20820630 DOI: 10.1039/C0Ib00054J  0.696
2010 Poon Z, Chen S, Engler AC, Lee HI, Atas E, von Maltzahn G, Bhatia SN, Hammond PT. Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting. Angewandte Chemie (International Ed. in English). 49: 7266-70. PMID 20740515 DOI: 10.1002/Anie.201003445  0.305
2010 Albrecht DR, Underhill GH, Resnikoff J, Mendelson A, Bhatia SN, Shah JV. Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics Integrative Biology. 2: 278-287. PMID 20532320 DOI: 10.1039/B923699F  0.685
2010 Ruoslahti E, Bhatia SN, Sailor MJ. Targeting of drugs and nanoparticles to tumors. The Journal of Cell Biology. 188: 759-68. PMID 20231381 DOI: 10.1083/Jcb.200910104  0.305
2010 Jones CT, Catanese MT, Law LM, Khetani SR, Syder AJ, Ploss A, Oh TS, Schoggins JW, MacDonald MR, Bhatia SN, Rice CM. Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system. Nature Biotechnology. 28: 167-71. PMID 20118917 DOI: 10.1038/Nbt.1604  0.318
2010 Harris TJ, Green JJ, Fung PW, Langer R, Anderson DG, Bhatia SN. Tissue-specific gene delivery via nanoparticle coating. Biomaterials. 31: 998-1006. PMID 19850333 DOI: 10.1016/J.Biomaterials.2009.10.012  0.401
2009 Agrawal A, Min DH, Singh N, Zhu H, Birjiniuk A, von Maltzahn G, Harris TJ, Xing D, Woolfenden SD, Sharp PA, Charest A, Bhatia S. Functional delivery of siRNA in mice using dendriworms. Acs Nano. 3: 2495-504. PMID 19673534 DOI: 10.1021/Nn900201E  0.31
2009 March S, Hui EE, Underhill GH, Khetani S, Bhatia SN. Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro. Hepatology (Baltimore, Md.). 50: 920-8. PMID 19585615 DOI: 10.1002/Hep.23085  0.794
2009 Park JH, Gu L, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nature Materials. 8: 331-6. PMID 19234444 DOI: 10.1038/Nmat2398  0.308
2009 Chen AA, Khetani SR, Lee S, Bhatia SN, Van Vliet KJ. Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers. Biomaterials. 30: 1113-20. PMID 19046762 DOI: 10.1016/J.Biomaterials.2008.10.055  0.425
2009 Underhill GH, Khetani SR, Chen AA, Bhatia SN. Tissue Engineering of the Liver The Liver: Biology and Pathobiology: Fifth Edition. 933-953. DOI: 10.1002/9780470747919.ch56  0.664
2008 Harris TJ, von Maltzahn G, Lord ME, Park JH, Agrawal A, Min DH, Sailor MJ, Bhatia SN. Protease-triggered unveiling of bioactive nanoparticles. Small (Weinheim An Der Bergstrasse, Germany). 4: 1307-12. PMID 18690639 DOI: 10.1002/Smll.200701319  0.303
2008 Khetani SR, Chen AA, Ranscht B, Bhatia SN. T-cadherin modulates hepatocyte functions in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3768-75. PMID 18635739 DOI: 10.1096/Fj.07-105155  0.376
2008 von Maltzahn G, Ren Y, Park JH, Min DH, Kotamraju VR, Jayakumar J, Fogal V, Sailor MJ, Ruoslahti E, Bhatia SN. In vivo tumor cell targeting with "click" nanoparticles. Bioconjugate Chemistry. 19: 1570-8. PMID 18611045 DOI: 10.1021/Bc800077Y  0.322
2008 Higgins JM, Eddington DT, Bhatia SN, Mahadevan L. Review of an in vitro microfluidic model of sickle cell vaso-occlusion. Transfusion Clinique Et Biologique : Journal De La SociéTé FrançAise De Transfusion Sanguine. 15: 12-3. PMID 18495515 DOI: 10.1016/J.Tracli.2008.04.010  0.339
2008 Flaim CJ, Teng D, Chien S, Bhatia SN. Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells and Development. 17: 29-39. PMID 18271698 DOI: 10.1089/Scd.2007.0085  0.316
2008 Khetani SR, Bhatia SN. Microscale culture of human liver cells for drug development. Nature Biotechnology. 26: 120-6. PMID 18026090 DOI: 10.1038/Nbt1361  0.45
2008 Liu WF, Hui EE, Bhatia SN, Chen CS. Engineering Cellular Microenvironments Principles of Regenerative Medicine. 536-553. DOI: 10.1016/B978-012369410-2.50032-2  0.585
2007 Hui EE, Bhatia SN. Silicon microchips for manipulating cell-cell interaction. Journal of Visualized Experiments : Jove. 268. PMID 18989439 DOI: 10.3791/268  0.682
2007 Higgins JM, Eddington DT, Bhatia SN, Mahadevan L. Sickle cell vasoocclusion and rescue in a microfluidic device. Proceedings of the National Academy of Sciences of the United States of America. 104: 20496-500. PMID 18077341 DOI: 10.1073/Pnas.0707122105  0.353
2007 Underhill GH, Bhatia SN. High-throughput analysis of signals regulating stem cell fate and function. Current Opinion in Chemical Biology. 11: 357-66. PMID 17656147 DOI: 10.1016/J.Cbpa.2007.05.036  0.681
2007 Derfus AM, Chen AA, Min DH, Ruoslahti E, Bhatia SN. Targeted quantum dot conjugates for siRNA delivery. Bioconjugate Chemistry. 18: 1391-6. PMID 17630789 DOI: 10.1021/Bc060367E  0.31
2007 Evans AR, Euteneuer S, Chavez E, Mullen LM, Hui EE, Bhatia SN, Ryan AF. Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in an in vitro alternate choice assay. Developmental Neurobiology. 67: 1721-30. PMID 17600813 DOI: 10.1002/Dneu.20540  0.627
2007 Albrecht DR, Underhill GH, Mendelson A, Bhatia SN. Multiphase electropatterning of cells and biomaterials. Lab On a Chip. 7: 702-9. PMID 17538711 DOI: 10.1039/B701306J  0.713
2007 Hui EE, Bhatia SN. Micromechanical control of cell-cell interactions. Proceedings of the National Academy of Sciences of the United States of America. 104: 5722-6. PMID 17389399 DOI: 10.1073/Pnas.0608660104  0.681
2007 Hui EE, Bhatia SN. Microscale control of cell contact and spacing via three-component surface patterning. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 4103-7. PMID 17243746 DOI: 10.1021/La0630559  0.653
2007 Liu Tsang V, Chen AA, Cho LM, Jadin KD, Sah RL, DeLong S, West JL, Bhatia SN. Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 790-801. PMID 17197384 DOI: 10.1096/Fj.06-7117Com  0.418
2007 Tsang VL, Bhatia SN. Fabrication of three-dimensional tissues. Advances in Biochemical Engineering/Biotechnology. 103: 189-205. PMID 17195464 DOI: 10.1007/10_010  0.344
2007 Underhill GH, Chen AA, Albrecht DR, Bhatia SN. Assessment of hepatocellular function within PEG hydrogels. Biomaterials. 28: 256-70. PMID 16979755 DOI: 10.1016/J.Biomaterials.2006.08.043  0.738
2007 Bhatia SN, Chen C, Bashir R, Beebe DJ, Cooper's J, Desai T, Gottwald E, Khademhosseini A, Langer RS, Piel M, Takayama S, Thorsen T, Tien J, Voldman J, Vunjak-Novakovic G, et al. Contributors to the Lab on a Chip cell and tissue engineering in microsystems special issue Lab On a Chip - Miniaturisation For Chemistry and Biology. 7: 667-671. DOI: 10.1039/B707012H  0.458
2007 Underhill GH, Khetani SR, Chen AA, Bhatia SN. Liver Principles of Tissue Engineering. 707-731. DOI: 10.1016/B978-012370615-7/50052-4  0.645
2006 Allen JW, Khetani SR, Johnson RS, Bhatia SN. In vitro liver tissue model established from transgenic mice: role of HIF-1alpha on hypoxic gene expression. Tissue Engineering. 12: 3135-47. PMID 17518628 DOI: 10.1089/Ten.2006.12.3135  0.354
2006 Khetani SR, Bhatia SN. Engineering tissues for in vitro applications. Current Opinion in Biotechnology. 17: 524-31. PMID 16978857 DOI: 10.1016/J.Copbio.2006.08.009  0.368
2006 Albrecht DR, Underhill GH, Wassermann TB, Sah RL, Bhatia SN. Probing the role of multicellular organization in three-dimensional microenvironments. Nature Methods. 3: 369-75. PMID 16628207 DOI: 10.1038/Nmeth873  0.702
2005 Chen AA, Derfus AM, Khetani SR, Bhatia SN. Quantum dots to monitor RNAi delivery and improve gene silencing. Nucleic Acids Research. 33: e190. PMID 16352864 DOI: 10.1093/Nar/Gni188  0.321
2005 Flaim CJ, Chien S, Bhatia SN. An extracellular matrix microarray for probing cellular differentiation. Nature Methods. 2: 119-25. PMID 15782209 DOI: 10.1038/Nmeth736  0.394
2005 Albrecht DR, Tsang VL, Sah RL, Bhatia SN. Photo- and electropatterning of hydrogel-encapsulated living cell arrays. Lab On a Chip. 5: 111-8. PMID 15616749 DOI: 10.1039/B406953F  0.392
2005 Allen JW, Khetani SR, Bhatia SN. In vitro zonation and toxicity in a hepatocyte bioreactor Toxicological Sciences. 84: 110-119. PMID 15590888 DOI: 10.1093/Toxsci/Kfi052  0.371
2004 Chin VI, Taupin P, Sanga S, Scheel J, Gage FH, Bhatia SN. Microfabricated platform for studying stem cell fates. Biotechnology and Bioengineering. 88: 399-415. PMID 15486946 DOI: 10.1002/Bit.20254  0.391
2004 Lin P, Chan WC, Badylak SF, Bhatia SN. Assessing porcine liver-derived biomatrix for hepatic tissue engineering. Tissue Engineering. 10: 1046-53. PMID 15363162 DOI: 10.1089/Ten.2004.10.1046  0.594
2004 Liu Tsang V, Bhatia SN. Three-dimensional tissue fabrication Advanced Drug Delivery Reviews. 56: 1635-1647. PMID 15350293 DOI: 10.1016/J.Addr.2004.05.001  0.348
2004 Khetani SR, Szulgit G, Del Rio JA, Barlow C, Bhatia SN. Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling. Hepatology (Baltimore, Md.). 40: 545-54. PMID 15349892 DOI: 10.1002/Hep.20351  0.429
2003 Allen JW, Bhatia SN. Formation of steady-state oxygen gradients in vitro: Application to liver zonation Biotechnology and Bioengineering. 82: 253-262. PMID 12599251 DOI: 10.1002/Bit.10569  0.324
2003 Gopalan SM, Flaim C, Bhatia SN, Hoshijima M, Knoell R, Chien KR, Omens JH, McCulloch AD. Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers. Biotechnology and Bioengineering. 81: 578-87. PMID 12514807 DOI: 10.1002/Bit.10506  0.329
2003 Ozkan M, Pisanic T, Scheel J, Barlow C, Esener S, Bhatia SN. Electro-optical platform for the manipulation of live cells Langmuir. 19: 1532-1538. DOI: 10.1021/La0261848  0.329
2002 Allen JW, Bhatia SN. Improving the next generation of bioartificial liver devices Seminars in Cell and Developmental Biology. 13: 447-454. PMID 12468246 DOI: 10.1016/S1084952102001337  0.34
2002 Allen JW, Bhatia SN. Engineering liver therapies for the future Tissue Engineering. 8: 725-737. PMID 12459052 DOI: 10.1089/10763270260424097  0.393
2002 Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E. Nanocrystal targeting in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 12617-21. PMID 12235356 DOI: 10.1073/Pnas.152463399  0.539
2002 Liu VA, Jastromb WE, Bhatia SN. Engineering protein and cell adhesivity using PEO-terminated triblock polymers Journal of Biomedical Materials Research. 60: 126-134. PMID 11835168 DOI: 10.1002/Jbm.10005  0.363
2002 Liu VA, Bhatia SN. Three-dimensional photopatterning of hydrogels containing living cells Biomedical Microdevices. 4: 257-266. DOI: 10.1023/A:1020932105236  0.41
2002 Vozzi G, Flaim CJ, Bianchi F, Ahluwalia A, Bhatia S. Microfabricated PLGA scaffolds: a comparative study for application to tissue engineering Materials Science and Engineering: C. 20: 43-47. DOI: 10.1016/S0928-4931(02)00011-5  0.309
2001 Allen JW, Hassanein T, Bhatia SN. Advances in bioartificial liver devices Hepatology. 34: 447-455. PMID 11526528 DOI: 10.1053/Jhep.2001.26753  0.35
2000 Behnia K, Bhatia S, Jastromb N, Balis U, Sullivan S, Yarmush M, Toner M. Xenobiotic metabolism by cultured primary porcine hepatocytes. Tissue Engineering. 6: 467-79. PMID 11074934 DOI: 10.1089/107632700750022125  0.581
1999 Balis UJ, Behnia K, Dwarakanath B, Bhatia SN, Sullivan SJ, Yarmush ML, Toner M. Oxygen consumption characteristics of porcine hepatocytes. Metabolic Engineering. 1: 49-62. PMID 10935754 DOI: 10.1006/Mben.1998.0105  0.577
1999 Bhatia SN, Balis UJ, Yarmush ML, Toner M. Effect of cell-cell interactions in preservation of cellular phenotype: Cocultivation of hepatocytes and nonparenchymal cells Faseb Journal. 13: 1883-1900. PMID 10544172 DOI: 10.1096/Fasebj.13.14.1883  0.645
1999 Ledezma GA, Folch A, Bhatia SN, Balis UJ, Yarmush ML, Toner M. Numerical model of fluid flow and oxygen transport in a radial-flow microchannel containing hepatocytes. Journal of Biomechanical Engineering. 121: 58-64. PMID 10080090 DOI: 10.1115/1.2798043  0.546
1999 Bhatia SN, Chen CS. Tissue Engineering at the Micro-Scale Biomedical Microdevices. 2: 131-144. DOI: 10.1023/A:1009949704750  0.357
1998 Bhatia SN, Balis UJ, Yarmush ML, Toner M. Probing heterotypic cell interactions: Hepatocyte function in microfabricated co-cultures Journal of Biomaterials Science, Polymer Edition. 9: 1137-1160. PMID 9860177 DOI: 10.1163/156856298X00695  0.645
1998 Bhatia SN, Balis UJ, Yarmush ML, Toner M. Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions Biotechnology Progress. 14: 378-387. PMID 9622518 DOI: 10.1021/Bp980036J  0.651
1997 Bhatia SN, Yarmush ML, Toner M. Controlling cell interactions by micropatterning in co-cultures: Hepatocytes and 3T3 fibroblasts Journal of Biomedical Materials Research. 34: 189-199. PMID 9029299 DOI: 10.1002/(Sici)1097-4636(199702)34:2<189::Aid-Jbm8>3.0.Co;2-M  0.634
1997 Bhatia SN, Yarmush ML, Toner M. Engineered substrates for controlling cell-cell interactions American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 37: 99-103.  0.436
1994 Bhatia SN, Toner M, Tompkins RG, Yarmush ML. Selective adhesion of hepatocytes on patterned surfaces Annals of the New York Academy of Sciences. 745: 187-209. PMID 7832508 DOI: 10.1111/J.1749-6632.1994.Tb44373.X  0.605
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