Lena G. Gerwick, Ph.D. - Publications

Oregon State University, Corvallis, OR 
Comparative immunology, parasitology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Maloney FP, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573844 DOI: 10.1073/Pnas.1607210113  0.92
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Gerwick L, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597  0.92
2016 Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH. The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide. Chembiochem : a European Journal of Chemical Biology. 17: 164-73. PMID 26769357 DOI: 10.1002/Cbic.201500467  0.92
2016 Kleigrewe K, Gerwick L, Sherman DH, Gerwick WH. Unique marine derived cyanobacterial biosynthetic genes for chemical diversity. Natural Product Reports. PMID 26758451 DOI: 10.1039/C5Np00097A  0.92
2015 Moss NA, Bertin MJ, Kleigrewe K, Leão TF, Gerwick L, Gerwick WH. Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery. Journal of Industrial Microbiology & Biotechnology. PMID 26578313 DOI: 10.1007/S10295-015-1705-7  0.92
2015 Teta R, Della Sala G, Glukhov E, Gerwick L, Gerwick WH, Mangoni A, Costantino V. A combined LC-MS/MS and molecular networking approach reveals new cyanotoxins from the 2014 cyanobacterial bloom in Green Lake, Seattle. Environmental Science & Technology. PMID 26567695 DOI: 10.1021/Acs.Est.5B04415  0.92
2015 Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Gerwick L, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890  0.92
2015 Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH. Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows. Plos One. 10: e0133297. PMID 26222584 DOI: 10.1371/Journal.Pone.0133297  0.92
2015 Shao CL, Linington RG, Balunas MJ, Centeno A, Boudreau P, Zhang C, Engene N, Spadafora C, Mutka TS, Kyle DE, Gerwick L, Wang CY, Gerwick WH. Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. The Journal of Organic Chemistry. PMID 26222145 DOI: 10.1021/Acs.Joc.5B01264  0.92
2015 Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. Journal of Natural Products. PMID 26149623 DOI: 10.1021/Acs.Jnatprod.5B00301  0.92
2015 Mascuch SJ, Moree WJ, Hsu CC, Turner GG, Cheng TL, Blehert DS, Kilpatrick AM, Frick WF, Meehan MJ, Dorrestein PC, Gerwick L. Direct detection of fungal siderophores on bats with white-nose syndrome via fluorescence microscopy-guided ambient ionization mass spectrometry. Plos One. 10: e0119668. PMID 25781976 DOI: 10.1371/Journal.Pone.0119668  0.92
2015 Bertin MJ, Schwartz SL, Lee J, Korobeynikov A, Dorrestein PC, Gerwick L, Gerwick WH. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. Journal of Natural Products. 78: 493-9. PMID 25668560 DOI: 10.1021/Np5009762  0.92
2014 Micallef ML, Sharma D, Bunn BM, Gerwick L, Viswanathan R, Moffitt MC. Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria. Bmc Microbiology. 14: 213. PMID 25198896 DOI: 10.1186/S12866-014-0213-7  0.92
2014 Coates RC, Podell S, Korobeynikov A, Lapidus A, Pevzner P, Sherman DH, Allen EE, Gerwick L, Gerwick WH. Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways. Plos One. 9: e85140. PMID 24475038 DOI: 10.1371/Journal.Pone.0085140  0.92
2013 Della Sala G, Hochmuth T, Costantino V, Teta R, Gerwick W, Gerwick L, Piel J, Mangoni A. Polyketide genes in the marine sponge Plakortis simplex: A new group of mono-modular type I polyketide synthases from sponge symbionts Environmental Microbiology Reports. 5: 809-818. PMID 24249289 DOI: 10.1111/1758-2229.12081  0.92
2013 Hsu CC, ElNaggar MS, Peng Y, Fang J, Sanchez LM, Mascuch SJ, Møller KA, Alazzeh EK, Pikula J, Quinn RA, Zeng Y, Wolfe BE, Dutton RJ, Gerwick L, Zhang L, et al. Real-time metabolomics on living microorganisms using ambient electrospray ionization flow-probe. Analytical Chemistry. 85: 7014-8. PMID 23819546 DOI: 10.1021/Ac401613X  0.92
2013 Sanchez LM, Knudsen GM, Helbig C, De Muylder G, Mascuch SM, Mackey ZB, Gerwick L, Clayton C, McKerrow JH, Linington RG. Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. Journal of Natural Products. 76: 630-41. PMID 23445522 DOI: 10.1021/Np300834Q  0.92
2013 Gerwick L, Boudreau P, Choi H, Mascuch S, Villa FA, Balunas MJ, Malloy KL, Teasdale ME, Rowley DC, Gerwick WH. Interkingdom signaling by structurally related cyanobacterial and algal secondary metabolites Phytochemistry Reviews. 12: 459-465. DOI: 10.1007/S11101-012-9237-5  0.92
2012 McCarthy JG, Eisman EB, Kulkarni S, Gerwick L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. Acs Chemical Biology. 7: 1994-2003. PMID 22991895 DOI: 10.1021/Cb300385M  0.92
2012 Balunas MJ, Grosso MF, Villa FA, Engene N, McPhail KL, Tidgewell K, Pineda LM, Gerwick L, Spadafora C, Kyle DE, Gerwick WH. Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Organic Letters. 14: 3878-81. PMID 22794317 DOI: 10.1021/Ol301607Q  0.92
2012 Choi H, Mascuch SJ, Villa FA, Byrum T, Teasdale ME, Smith JE, Preskitt LB, Rowley DC, Gerwick L, Gerwick WH. Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships. Chemistry & Biology. 19: 589-98. PMID 22633410 DOI: 10.1016/J.Chembiol.2012.03.014  0.92
2012 Kim JW, Gerwick L, Park CI. Molecular identification and expression analysis of two distinct BPI/LBPs (bactericidal permeability-increasing protein/LPS-binding protein) from rock bream, Oplegnathus fasciatus Fish and Shellfish Immunology. 33: 75-84. PMID 22521422 DOI: 10.1016/J.Fsi.2012.04.003  0.92
2012 Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. The Febs Journal. 279: 1243-51. PMID 22314229 DOI: 10.1111/J.1742-4658.2012.08517.X  0.92
2012 Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Structure and activity of DmmA, a marine haloalkane dehalogenase. Protein Science : a Publication of the Protein Society. 21: 239-48. PMID 22124946 DOI: 10.1002/Pro.2009  0.92
2012 Carland TM, Locke JB, Nizet V, Gerwick L. Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Developmental and Comparative Immunology. 36: 31-8. PMID 21683091 DOI: 10.1016/J.Dci.2011.05.013  0.92
2011 Engene N, Choi H, Esquenazi E, Byrum T, Villa FA, Cao Z, Murray TF, Dorrestein PC, Gerwick L, Gerwick WH. Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera. Journal of Natural Products. 74: 1737-43. PMID 21751786 DOI: 10.1021/Np200236C  0.92
2011 Jones AC, Monroe EA, Podell S, Hess WR, Klages S, Esquenazi E, Niessen S, Hoover H, Rothmann M, Lasken RS, Yates JR, Reinhardt R, Kube M, Burkart MD, Allen EE, ... ... Gerwick L, et al. Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proceedings of the National Academy of Sciences of the United States of America. 108: 8815-20. PMID 21555588 DOI: 10.1073/Pnas.1101137108  0.92
2011 Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH. Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage. Plos One. 6: e18565. PMID 21533272 DOI: 10.1371/Journal.Pone.0018565  0.92
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/Aem.00038-11  0.92
2011 Malloy KL, Villa FA, Engene N, Matainaho T, Gerwick L, Gerwick WH. Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium. Journal of Natural Products. 74: 95-8. PMID 21155594 DOI: 10.1021/Np1005407  0.92
2010 Jones AC, Monroe EA, Eisman EB, Gerwick L, Sherman DH, Gerwick WH. The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. Natural Product Reports. 27: 1048-65. PMID 20442916 DOI: 10.1039/C000535E  0.92
2010 Villa FA, Gerwick L. Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders. Immunopharmacology and Immunotoxicology. 32: 228-37. PMID 20441539 DOI: 10.3109/08923970903296136  0.92
2010 Carland TM, Gerwick L. The C1q domain containing proteins: Where do they come from and what do they do? Developmental and Comparative Immunology. 34: 785-790. PMID 20214925 DOI: 10.1016/J.Dci.2010.02.014  0.92
2010 Villa FA, Lieske K, Gerwick L. Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate. European Journal of Pharmacology. 629: 140-6. PMID 20006962 DOI: 10.1016/J.Ejphar.2009.12.002  0.92
2009 Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. Bmc Microbiology. 9: 247. PMID 19951434 DOI: 10.1186/1471-2180-9-247  0.92
2009 Gu L, Wang B, Kulkarni A, Gehret JJ, Lloyd KR, Gerwick L, Gerwick WH, Wipf P, HÃ¥kansson K, Smith JL, Sherman DH. Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. Journal of the American Chemical Society. 131: 16033-5. PMID 19835378 DOI: 10.1021/Ja9071578  0.92
2009 Gu L, Wang B, Kulkarni A, Geders TW, Grindberg RV, Gerwick L, HÃ¥kansson K, Wipf P, Smith JL, Gerwick WH, Sherman DH. Metamorphic enzyme assembly in polyketide diversification. Nature. 459: 731-5. PMID 19494914 DOI: 10.1038/Nature07870  0.92
2008 Simmons TL, Engene N, Ureña LD, Romero LI, Ortega-Barría E, Gerwick L, Gerwick WH. Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis. Journal of Natural Products. 71: 1544-50. PMID 18715036 DOI: 10.1021/Np800110E  0.92
2008 Gerwick WH, Coates RC, Engene N, Gerwick L, Grindberg RV, Jones AC, Sorrels CM. Giant marine cyanobacteria produce exciting potential pharmaceuticals Microbe. 3: 277-284. DOI: 10.1128/Microbe.3.277.1  0.92
2007 Momoda TS, Schwindt AR, Feist GW, Gerwick L, Bayne CJ, Schreck CB. Gene expression in the liver of rainbow trout, Oncorhynchus mykiss, during the stress response. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 2: 303-15. PMID 20483302 DOI: 10.1016/J.Cbd.2007.06.002  0.92
2007 Gerwick L, Corley-Smith G, Bayne CJ. Gene transcript changes in individual rainbow trout livers following an inflammatory stimulus. Fish & Shellfish Immunology. 22: 157-71. PMID 16762566 DOI: 10.1016/J.Fsi.2006.04.003  0.92
2006 Bayne CJ, Gerwick L, Wheeler PA, Thorgaard GH. Transcriptome profiles of livers and kidneys from three rainbow trout (Oncorhynchus mykiss) clonal lines distinguish stocks from three allopatric populations. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 1: 396-403. PMID 20483271 DOI: 10.1016/J.Cbd.2006.10.001  0.92
2005 Tilton SC, Gerwick LG, Hendricks JD, Rosato CS, Corley-Smith G, Givan SA, Bailey GS, Bayne CJ, Williams DE. Use of a rainbow trout oligonucleotide microarray to determine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 319-30. PMID 16141433 DOI: 10.1093/Toxsci/Kfi309  0.92
2005 Gerwick L, Corley-Smith GE, Nakao M, Watson J, Bayne CJ. Intracranial injections induce local transcription of a gene encoding precerebellin-like protein Fish Physiology and Biochemistry. 31: 363-372. DOI: 10.1007/S10695-005-4588-0  0.92
2003 Fujiki K, Gerwick L, Bayne CJ, Mitchell L, Gauley J, Bols N, Dixon B. Molecular cloning and characterization of rainbow trout (Oncorhynchus mykiss) CCAAT/enhancer binding protein beta. Immunogenetics. 55: 253-61. PMID 12774179 DOI: 10.1007/S00251-003-0576-7  0.92
2002 Gerwick L, Steinhauer R, Lapatra S, Sandell T, Ortuno J, Hajiseyedjavadi N, Bayne CJ. The acute phase response of rainbow trout (Oncorhynchus mykiss) plasma proteins to viral, bacterial and fungal inflammatory agents. Fish & Shellfish Immunology. 12: 229-42. PMID 11931018 DOI: 10.1006/Fsim.2001.0367  0.92
2001 Bayne CJ, Gerwick L. The acute phase response and innate immunity of fish. Developmental and Comparative Immunology. 25: 725-43. PMID 11602193 DOI: 10.1016/S0145-305X(01)00033-7  0.92
2001 Bayne CJ, Gerwick L, Fujiki K, Nakao M, Yano T. Immune-relevant (including acute phase) genes identified in the livers of rainbow trout, Oncorhynchus mykiss, by means of suppression subtractive hybridization. Developmental and Comparative Immunology. 25: 205-17. PMID 11164886 DOI: 10.1016/S0145-305X(00)00057-4  0.92
2000 Gerwick L, Reynolds WS, Bayne CJ. A precerebellin-like protein is part of the acute phase response in rainbow trout, Oncorhynchus mykiss. Developmental and Comparative Immunology. 24: 597-607. PMID 10831794 DOI: 10.1016/S0145-305X(00)00016-1  0.92
1999 Gerwick L, Demers NE, Bayne CJ. Modulation of stress hormones in rainbow trout by means of anesthesia, sensory deprivation and receptor blockade. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 124: 329-34. PMID 10665382 DOI: 10.1016/S1095-6433(99)00126-9  0.92
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