Alexander P. Gorka, Ph.D. - Publications

Affiliations: 
2013 Chemistry Georgetown University, Washington, DC 
Area:
Parasitology, Biochemistry, Molecular Biology

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Gorka AP, Schnermann MJ. Harnessing cyanine photooxidation: from slowing photobleaching to near-IR uncaging. Current Opinion in Chemical Biology. 33: 117-125. PMID 27348157 DOI: 10.1016/j.cbpa.2016.05.022  0.76
2016 Medina SH, Miller SE, Keim AI, Gorka AP, Schnermann MJ, Schneider JP. An Intrinsically Disordered Peptide Facilitates Non-Endosomal Cell Entry. Angewandte Chemie (International Ed. in English). PMID 26835878 DOI: 10.1002/anie.201510518  0.76
2015 Sato K, Gorka AP, Nagaya T, Michie MS, Nani RR, Nakamura Y, Coble VL, Vasalatiy OV, Swenson RE, Choyke PL, Schnermann MJ, Kobayashi H. Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates. Bioconjugate Chemistry. PMID 26444497 DOI: 10.1021/acs.bioconjchem.5b00492  0.76
2015 Nani RR, Gorka AP, Nagaya T, Kobayashi H, Schnermann MJ. Near-IR Light-Mediated Cleavage of Antibody-Drug Conjugates Using Cyanine Photocages. Angewandte Chemie (International Ed. in English). 54: 13635-8. PMID 26403799 DOI: 10.1002/anie.201507391  0.76
2015 Sato K, Nagaya T, Nakamura Y, Harada T, Nani RR, Shaum JB, Gorka AP, Kim I, Paik CH, Choyke PL, Schnermann MJ, Kobayashi H. Impact of C4'-O-Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates. Molecular Pharmaceutics. 12: 3303-11. PMID 26261913 DOI: 10.1021/acs.molpharmaceut.5b00472  0.76
2015 Gorka AP, Nani RR, Schnermann MJ. Cyanine polyene reactivity: scope and biomedical applications. Organic & Biomolecular Chemistry. PMID 26052876 DOI: 10.1039/c5ob00788g  0.76
2015 Nani RR, Shaum JB, Gorka AP, Schnermann MJ. Electrophile-integrating Smiles rearrangement provides previously inaccessible C4'-O-alkyl heptamethine cyanine fluorophores. Organic Letters. 17: 302-5. PMID 25562683 DOI: 10.1021/ol503398f  0.76
2014 Gorka AP, Nani RR, Zhu J, Mackem S, Schnermann MJ. A near-IR uncaging strategy based on cyanine photochemistry. Journal of the American Chemical Society. 136: 14153-9. PMID 25211609 DOI: 10.1021/ja5065203  0.76
2013 Suberu JO, Gorka AP, Jacobs L, Roepe PD, Sullivan N, Barker GC, Lapkin AA. Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanisms. Plos One. 8: e80790. PMID 24244716 DOI: 10.1371/journal.pone.0080790  0.76
2013 Gorka AP, Jacobs LM, Roepe PD. Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis. Malaria Journal. 12: 332. PMID 24044530 DOI: 10.1186/1475-2875-12-332  0.76
2013 Gorka AP, de Dios A, Roepe PD. Quinoline drug-heme interactions and implications for antimalarial cytostatic versus cytocidal activities. Journal of Medicinal Chemistry. 56: 5231-46. PMID 23586757 DOI: 10.1021/jm400282d  0.76
2013 Harinantenaina L, Bowman JD, Brodie PJ, Slebodnick C, Callmander MW, Rakotobe E, Randrianaivo R, Rasamison VE, Gorka A, Roepe PD, Cassera MB, Kingston DG. Antiproliferative and antiplasmodial dimeric phloroglucinols from Mallotus oppositifolius from the Madagascar Dry Forest (1). Journal of Natural Products. 76: 388-93. PMID 23286240 DOI: 10.1021/np300750q  0.76
2013 Gorka AP, Alumasa JN, Sherlach KS, Jacobs LM, Nickley KB, Brower JP, de Dios AC, Roepe PD. Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth. Antimicrobial Agents and Chemotherapy. 57: 356-64. PMID 23114783 DOI: 10.1128/AAC.01709-12  0.76
2013 Gorka AP, Sherlach KS, de Dios AC, Roepe PD. Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 57: 365-74. PMID 23114754 DOI: 10.1128/AAC.01234-12  0.76
2012 Dinio T, Gorka AP, McGinniss A, Roepe PD, Morgan JB. Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum. Bioorganic & Medicinal Chemistry. 20: 3292-7. PMID 22512909 DOI: 10.1016/j.bmc.2012.03.042  0.76
2011 Pan E, Gorka AP, Alumasa JN, Slebodnick C, Harinantenaina L, Brodie PJ, Roepe PD, Randrianaivo R, Birkinshaw C, Kingston DG. Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. Journal of Natural Products. 74: 2174-80. PMID 21995542 DOI: 10.1021/np200499d  0.76
2011 Sherlach KS, Gorka AP, Dantzler A, Roepe PD. Quantification of perchloroethylene residues in dry-cleaned fabrics. Environmental Toxicology and Chemistry / Setac. 30: 2481-7. PMID 21898565 DOI: 10.1002/etc.665  0.76
2011 Alumasa JN, Gorka AP, Casabianca LB, Comstock E, de Dios AC, Roepe PD. The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. Journal of Inorganic Biochemistry. 105: 467-75. PMID 20864177 DOI: 10.1016/j.jinorgbio.2010.08.011  0.76
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