Wai-keung Leung, Ph.D. - Publications

Affiliations: 
2001 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Medicine and Surgery, Epidemiology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ooi CJ, Hilmi I, Banerjee R, Chuah SW, Ng SC, Wei SC, Makharia GK, Pisespongsa P, Chen MH, Ran ZH, Ye BD, Park DI, Ling KL, Ong D, Ahuja V, ... ... Leung WK, et al. Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia. Intestinal Research. PMID 31146509 DOI: 10.5217/ir.2019.00026  0.44
2018 Mak WY, Mak OS, Lee CK, Tang W, Leung WK, Wong MTL, Sze ASF, Li M, Leung CM, Lo FH, Lam BCY, Chan KH, Shan EHS, Tsang SWC, Hui AJ, et al. Significant medical and surgical morbidity in perianal Crohn's disease: Results from a territory-wide study. Journal of Crohn's & Colitis. PMID 30165543 DOI: 10.1093/ecco-jcc/jjy120  0.32
2017 So J, Tang W, Leung WK, Li M, Lo FH, Wong MTL, Sze ASF, Leung CM, Tsang SWC, Shan EHS, Chan KH, Lam BCY, Hui AJ, Chow WH, Lam TY, et al. Cancer Risk in 2621 Chinese Patients with Inflammatory Bowel Disease: A Population-based Cohort Study. Inflammatory Bowel Diseases. PMID 28991855 DOI: 10.1097/MIB.0000000000001240  0.32
2016 Ng SC, Leung WK, Shi HY, Li MK, Leung CM, Ng CK, Lo FH, Hui YT, Tsang SW, Chan YK, Loo CK, Chan KH, Hui AJ, Chow WH, Harbord M, et al. Epidemiology of Inflammatory Bowel Disease from 1981 to 2014: Results from a Territory-Wide Population-Based Registry in Hong Kong. Inflammatory Bowel Diseases. PMID 27416041 DOI: 10.1097/MIB.0000000000000846  0.32
2016 Shi HY, Chan FK, Leung WK, Li MK, Leung CM, Sze SF, Ching JY, Lo FH, Tsang SW, Shan EH, Mak LY, Lam BC, Hui AJ, Chow WH, Wong MT, et al. Low-dose azathioprine is effective in maintaining remission in steroid-dependent ulcerative colitis: results from a territory-wide Chinese population-based IBD registry. Therapeutic Advances in Gastroenterology. 9: 449-56. PMID 27366213 DOI: 10.1177/1756283X16643509  0.32
2016 Liu KS, Wong IO, Leung WK. Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance. World Journal of Gastroenterology. 22: 1311-20. PMID 26811668 DOI: 10.3748/wjg.v22.i3.1311  0.32
2016 Lam YF, Leung WK. The Importance of Increased Serrated Polyp Detection Rate Current Colorectal Cancer Reports. 1-7. DOI: 10.1007/s11888-016-0313-x  0.32
2015 Hon SS, Ng SS, Wong TC, Chiu PW, Mak TW, Leung WW, Lee JF. Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia. World Journal of Gastrointestinal Endoscopy. 7: 1243-1249. PMID 26634040 DOI: 10.4253/wjge.v7.i17.1243  0.44
2015 Shi HY, Chan FK, Leung WK, Li MK, Leung CM, Sze SF, Ching JY, Lo FH, Tsang SW, Shan EH, Mak LY, Lam BC, Hui AJ, Wong SH, Wong MT, et al. Natural History of Elderly-onset Ulcerative Colitis: Results from a Territory-wide Inflammatory Bowel Disease Registry. Journal of Crohn's & Colitis. PMID 26512132 DOI: 10.1093/ecco-jcc/jjv194  0.68
2015 Leung WK, Chen WQ, Gu L, Long D, Law WL. Distributions of colorectal cancer in two chinese cities with contrasting colorectal cancer epidemiology. Journal of Gastroenterology and Hepatology. PMID 26095432 DOI: 10.1111/jgh.13018  0.32
2015 Ooi CJ, Hilmi I, Makharia GK, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, et al. The Asia Pacific Consensus Statements on Crohn's Disease Part 2: Management. Journal of Gastroenterology and Hepatology. PMID 25819311 DOI: 10.1111/jgh.12958  0.32
2015 Ooi CJ, Hilmi I, Makharia GK, Gibson PR, Fock KM, Ahuja V, Ling KL, Lim WC, Thia KT, Wei SC, Leung WK, Koh PK, Gearry RB, Goh KL, Ouyang Q, et al. The Asia Pacific Consensus Statements on Crohn's Disease Part 1: definition, diagnosis and epidemiology. Journal of Gastroenterology and Hepatology. PMID 25819140 DOI: 10.1111/jgh.12956  0.32
2014 Wu CW, Ng SC, Dong Y, Tian L, Ng SS, Leung WW, Law WT, Yau TO, Chan FK, Sung JJ, Yu J. Identification of microRNA-135b in stool as a potential noninvasive biomarker for colorectal cancer and adenoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2994-3002. PMID 24691020 DOI: 10.1158/1078-0432.CCR-13-1750  0.32
2013 Dong Y, Zhao J, Wu CW, Zhang L, Liu X, Kang W, Leung WW, Zhang N, Chan FK, Sung JJ, Ng SS, Yu J. Tumor suppressor functions of miR-133a in colorectal cancer. Molecular Cancer Research : McR. 11: 1051-60. PMID 23723074 DOI: 10.1158/1541-7786.MCR-13-0061  0.32
2013 Ng SC, Lau JY, Chan FK, Suen BY, Leung WK, Tse YK, Ng SS, Lee JF, To KF, Wu JC, Sung JJ. Increased risk of advanced neoplasms among asymptomatic siblings of patients with colorectal cancer. Gastroenterology. 144: 544-50. PMID 23159367 DOI: 10.1053/j.gastro.2012.11.011  0.68
2012 Leung WK, Ho SS, Suen BY, Lai LH, Yu S, Ng EK, Ng SS, Chiu PW, Sung JJ, Chan FK, Lau JY. Capsule endoscopy or angiography in patients with acute overt obscure gastrointestinal bleeding: a prospective randomized study with long-term follow-up. The American Journal of Gastroenterology. 107: 1370-6. PMID 22825363 DOI: 10.1038/ajg.2012.212  0.68
2012 Wu CW, Ng SS, Dong YJ, Ng SC, Leung WW, Lee CW, Wong YN, Chan FK, Yu J, Sung JJ. Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps. Gut. 61: 739-45. PMID 21930727 DOI: 10.1136/gut.2011.239236  0.32
2011 Shin VY, Jin HC, Ng EK, Cho CH, Leung WK, Sung JJ, Chu KM. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro. Cancer Science. 102: 926-33. PMID 21261791 DOI: 10.1111/j.1349-7006.2011.01885.x  0.68
2011 Shin VY, Jin H, Ng EK, Cheng AS, Chong WW, Wong CY, Leung WK, Sung JJ, Chu KM. NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. Carcinogenesis. 32: 240-5. PMID 21081469 DOI: 10.1093/carcin/bgq240  0.68
2010 Leung WK, Chan PK, Lee NL, Sung JJ. Development of an in vitro cell culture model for human noroviruses and its clinical application. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 16: 18-21. PMID 20864742  0.68
2010 Leung WK, Chan HL, Lai RW, Sung JJ. Establishment of public norovirus genome database in Hong Kong. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 16: 4-7. PMID 20864738  0.68
2010 Ooi CJ, Fock KM, Makharia GK, Goh KL, Ling KL, Hilmi I, Lim WC, Kelvin T, Gibson PR, Gearry RB, Ouyang Q, Sollano J, Manatsathit S, Rerknimitr R, Wei SC, ... Leung WK, et al. The Asia-Pacific consensus on ulcerative colitis. Journal of Gastroenterology and Hepatology. 25: 453-68. PMID 20370724 DOI: 10.1111/j.1440-1746.2010.06241.x  0.32
2009 Li J, Ng EK, Ng YP, Wong CY, Yu J, Jin H, Cheng VY, Go MY, Cheung PK, Ebert MP, Tong J, To KF, Chan FK, Sung JJ, Ip NY, ... Leung WK, et al. Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer. British Journal of Cancer. 101: 691-8. PMID 19672268 DOI: 10.1038/sj.bjc.6605202  0.32
2009 Leung WK, Lau JY, Suen BY, Wong GL, Chow DK, Lai LH, To KF, Yim CK, Lee ES, Tsoi KK, Ng SS, Sung JJ. Repeat-screening colonoscopy 5 years after normal baseline-screening colonoscopy in average-risk Chinese: a prospective study. The American Journal of Gastroenterology. 104: 2028-34. PMID 19455125 DOI: 10.1038/ajg.2009.202  0.32
2009 Chow DK, Leong RW, Tsoi KK, Ng SS, Leung WK, Wu JC, Wong VW, Chan FK, Sung JJ. Long-term follow-up of ulcerative colitis in the Chinese population. The American Journal of Gastroenterology. 104: 647-54. PMID 19262521 DOI: 10.1038/ajg.2008.74  0.68
2009 Lee YT, Lai LH, Hui AJ, Wong VW, Ching JY, Wong GL, Wu JC, Chan HL, Leung WK, Lau JY, Sung JJ, Chan FK. Efficacy of cap-assisted colonoscopy in comparison with regular colonoscopy: a randomized controlled trial. The American Journal of Gastroenterology. 104: 41-6. PMID 19098847 DOI: 10.1038/ajg.2008.56  0.68
2009 Chiu PW, Ng EK, Cheung FK, Chan FK, Leung WK, Wu JC, Wong VW, Yung MY, Tsoi K, Lau JY, Sung JJ, Chung SS. Predicting mortality in patients with bleeding peptic ulcers after therapeutic endoscopy. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: 311-6; quiz 253. PMID 18955161 DOI: 10.1016/j.cgh.2008.08.044  0.68
2008 Cheng YY, Jin H, Liu X, Siu JM, Wong YP, Ng EK, Yu J, Leung WK, Sung JJ, Chan FK. Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer. British Journal of Cancer. 99: 2083-7. PMID 18985039 DOI: 10.1038/sj.bjc.6604760  0.68
2008 Chen BL, Yu J, Zeng ZR, Chu WK, Wong CY, Cheng YY, Sung JJ, Hu PJ, Leung WK. Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression. Oncology Reports. 20: 1093-7. PMID 18949406  0.68
2008 Shin VY, Jin HC, Ng EK, Yu J, Leung WK, Cho CH, Sung JJ. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. Toxicology and Applied Pharmacology. 233: 254-61. PMID 18805435 DOI: 10.1016/j.taap.2008.08.012  0.68
2008 Chan MC, Wong YP, Sung JJ, Leung WK. Histo-blood group antigens and susceptibility to infection with norovirus genogroup II genotype 4. The Journal of Infectious Diseases. 198: 940; author reply 94. PMID 18721065 DOI: 10.1086/588707  0.68
2008 Leung WK, Wu KC, Wong CY, Cheng AS, Ching AK, Chan AW, Chong WW, Go MY, Yu J, To KF, Wang X, Chui YL, Fan DM, Sung JJ. Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice. Carcinogenesis. 29: 1648-54. PMID 18611916 DOI: 10.1093/carcin/bgn156  0.32
2008 Leung WK, Wu MS, Kakugawa Y, Kim JJ, Yeoh KG, Goh KL, Wu KC, Wu DC, Sollano J, Kachintorn U, Gotoda T, Lin JT, You WC, Ng EK, Sung JJ, et al. Screening for gastric cancer in Asia: current evidence and practice. The Lancet. Oncology. 9: 279-87. PMID 18308253 DOI: 10.1016/S1470-2045(08)70072-X  0.32
2008 Lee YT, Chan FK, Leung WK, Chan HL, Wu JC, Yung MY, Ng EK, Lau JY, Sung JJ. Comparison of EUS and ERCP in the investigation with suspected biliary obstruction caused by choledocholithiasis: a randomized study. Gastrointestinal Endoscopy. 67: 660-8. PMID 18155205 DOI: 10.1016/j.gie.2007.07.025  0.68
2008 Chow DK, Leong RW, Lai LH, Wong GL, Leung WK, Chan FK, Sung JJ. Changes in Crohn's disease phenotype over time in the Chinese population: validation of the Montreal classification system. Inflammatory Bowel Diseases. 14: 536-41. PMID 18058793 DOI: 10.1002/ibd.20335  0.68
2007 Lee N, Chan MC, Wong B, Choi KW, Sin W, Lui G, Chan PK, Lai RW, Cockram CS, Sung JJ, Leung WK. Fecal viral concentration and diarrhea in norovirus gastroenteritis. Emerging Infectious Diseases. 13: 1399-401. PMID 18252121 DOI: 10.3201/eid1309.061535  0.68
2007 Chan MW, Wong CY, Cheng AS, Chan VY, Chan KK, To KF, Chan FK, Sung JJ, Leung WK. Targeted inhibition of COX-2 expression by RNA interference suppresses tumor growth and potentiates chemosensitivity to cisplatin in human gastric cancer cells. Oncology Reports. 18: 1557-62. PMID 17982644  0.68
2007 Lai LH, Wong GL, Lau JY, Sung JJ, Leung WK. Initial experience of real-time capsule endoscopy in monitoring progress of the videocapsule through the upper GI tract. Gastrointestinal Endoscopy. 66: 1211-4. PMID 17945224 DOI: 10.1016/j.gie.2007.04.011  0.68
2007 Cheng YY, Yu J, Wong YP, Man EP, To KF, Jin VX, Li J, Tao Q, Sung JJ, Chan FK, Leung WK. Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. British Journal of Cancer. 97: 895-901. PMID 17848950 DOI: 10.1038/sj.bjc.6603968  0.68
2007 Leung WK, Wu JC, Chan FK, Fung SS, Wong VW, Hui AJ, Hung LC, Sung JJ. Initial treatment with lansoprazole in young dyspeptic patients with negative urea breath test result: a randomized controlled trial with 12-month follow-up. The American Journal of Gastroenterology. 102: 1483-8. PMID 17593161 DOI: 10.1111/j.1572-0241.2007.01229.x  0.68
2007 Byeon JS, Yang SK, Kim TI, Kim WH, Lau JY, Leung WK, Fujita R, Makharia GK, Abdullah M, Hilmi I, Sollano J, Yeoh KG, Wu DC, Chen MH, Kongkam P, et al. Colorectal neoplasm in asymptomatic Asians: a prospective multinational multicenter colonoscopy survey. Gastrointestinal Endoscopy. 65: 1015-22. PMID 17531636 DOI: 10.1016/j.gie.2006.12.065  0.68
2007 Chan FK, Wong VW, Suen BY, Wu JC, Ching JY, Hung LC, Hui AJ, Leung VK, Lee VW, Lai LH, Wong GL, Chow DK, To KF, Leung WK, Chiu PW, et al. Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. Lancet (London, England). 369: 1621-6. PMID 17499604 DOI: 10.1016/S0140-6736(07)60749-1  0.68
2007 Ren TH, Wu J, Yew D, Ziea E, Lao L, Leung WK, Berman B, Hu PJ, Sung JJ. Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G849-56. PMID 17110521 DOI: 10.1152/ajpgi.00400.2006  0.32
2006 Hui AY, Leung WK, Chan HL, Chan FK, Go MY, Chan KK, Tang BD, Chu ES, Sung JJ. Effect of celecoxib on experimental liver fibrosis in rat. Liver International : Official Journal of the International Association For the Study of the Liver. 26: 125-36. PMID 16420518 DOI: 10.1111/j.1478-3231.2005.01202.x  0.32
2005 Jin Y, Leung WK, Sung JJ, Wu JR. p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells. Cell Research. 15: 695-703. PMID 16212876 DOI: 10.1038/sj.cr.7290339  0.68
2005 Li Y, Jiang ZZ, Chen HX, Leung WK, Sung JJ, Ma WJ. The existence of a putative regulatory element in 3'-untranslated region of proto-oncogene HOX11's mRNA. Journal of Biochemistry and Molecular Biology. 38: 500-6. PMID 16053719  0.68
2005 Hung LC, Ching JY, Sung JJ, To KF, Hui AJ, Wong VW, Leong RW, Chan HL, Wu JC, Leung WK, Lee YT, Chung SC, Chan FK. Long-term outcome of Helicobacter pylori-negative idiopathic bleeding ulcers: a prospective cohort study. Gastroenterology. 128: 1845-50. PMID 15940620  0.68
2005 Chan WS, Wu C, Chow SC, Cheung T, To KF, Leung WK, Chan PK, Lee KC, Ng HK, Au DM, Lo AW. Coronaviral hypothetical and structural proteins were found in the intestinal surface enterocytes and pneumocytes of severe acute respiratory syndrome (SARS). Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 1432-9. PMID 15920543 DOI: 10.1038/modpathol.3800439  0.44
2005 Hui AY, Hung LC, Tse PC, Leung WK, Chan PK, Chan HL. Transmission of hepatitis B by human bite--confirmation by detection of virus in saliva and full genome sequencing. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 33: 254-6. PMID 15911449 DOI: 10.1016/j.jcv.2005.02.006  0.32
2005 Chan HL, Kwan AC, To KF, Lai ST, Chan PK, Leung WK, Lee N, Wu A, Sung JJ. Clinical significance of hepatic derangement in severe acute respiratory syndrome. World Journal of Gastroenterology : Wjg. 11: 2148-53. PMID 15810082  0.68
2005 Chan AW, Chan MW, Lee TL, Ng EK, Leung WK, Lau JY, Tong JH, Chan FK, To KF. Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer. Oncology Reports. 13: 937-41. PMID 15809761  0.68
2005 Chan VY, Chan MW, Leung WK, Leung PS, Sung JJ, Chan FK. Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell. Regulatory Peptides. 127: 87-94. PMID 15680474 DOI: 10.1016/j.regpep.2004.10.016  0.68
2004 Chan HL, Leung WK, To KF, Chan PK, Lee N, Wu A, Tam JS, Sung JJ. Retrospective analysis of liver function derangement in severe acute respiratory syndrome. The American Journal of Medicine. 116: 566-7. PMID 15063822 DOI: 10.1016/j.amjmed.2003.11.024  0.68
2004 Liu ZM, Chen GG, Ng EK, Leung WK, Sung JJ, Chung SC. Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene. 23: 503-13. PMID 14647439 DOI: 10.1038/sj.onc.1207173  0.68
2003 Song W, Leung WK, Chan HL. Icteric flare of chronic hepatitis B in a 95-year old patient. World Journal of Gastroenterology. 9: 2876-7. PMID 14669358  0.52
2003 Sung JJ, Chan FK, Lau JY, Yung MY, Leung WK, Wu JC, Ng EK, Chung SC. The effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots: a randomized comparison. Annals of Internal Medicine. 139: 237-43. PMID 12965978  0.68
2002 Leung WK, Hung LC, Kwok CK, Leong RW, Ng DK, Sung JJ. Follow up of serial urea breath test results in patients after consumption of antibiotics for non-gastric infections. World Journal of Gastroenterology : Wjg. 8: 703-6. PMID 12174382  0.68
2002 Wu JC, Chan FK, Ching JY, Leung WK, Lee YT, Sung JJ. Empirical treatment based on "typical" reflux symptoms is inappropriate in a population with a high prevalence of Helicobacter pylori infection. Gastrointestinal Endoscopy. 55: 461-5. PMID 11923754 DOI: 10.1067/mge.2002.122617  0.68
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