Michelle M. Mielke, Ph.D. - Publications

Affiliations: 
2005 Johns Hopkins University, Baltimore, MD 
Area:
Mental Health, Epidemiology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Miller VM, Garovic VD, Bailey KR, Lahr BD, Mielke MM, White WM, Jayachandran M. Pregnancy history and blood-borne microvesicles in middle aged women with and without coronary artery calcification. Atherosclerosis. 253: 150-155. PMID 27639028 DOI: 10.1016/j.atherosclerosis.2016.09.006  0.56
2016 Knopman DS, Jack CR, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiology of Aging. 46: 32-42. PMID 27460147 DOI: 10.1016/j.neurobiolaging.2016.06.003  0.56
2016 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, Petersen RC. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology. PMID 27421543 DOI: 10.1212/WNL.0000000000002979  0.56
2016 Vassilaki M, Aakre JA, Mielke MM, Geda YE, Kremers WK, Alhurani RE, Machulda MM, Knopman DS, Petersen RC, Lowe VJ, Jack CR, Roberts RO. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology. PMID 27164657 DOI: 10.1212/WNL.0000000000002624  0.56
2016 Kantarci K, Lowe VJ, Lesnick TG, Tosakulwong N, Bailey KR, Fields JA, Shuster LT, Zuk SM, Senjem ML, Mielke MM, Gleason C, Jack CR, Rocca WA, Miller VM. Early Postmenopausal Transdermal 17β-Estradiol Therapy and Amyloid-β Deposition. Journal of Alzheimer's Disease : Jad. PMID 27163830 DOI: 10.3233/JAD-160258  0.56
2016 Savica R, Murray ME, Persson XM, Kantarci K, Parisi JE, Dickson DW, Petersen RC, Ferman TJ, Boeve BF, Mielke MM. Plasma sphingolipid changes with autopsy-confirmed Lewy Body or Alzheimer's pathology. Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 43-50. PMID 27152320 DOI: 10.1016/j.dadm.2016.02.005  0.56
2016 Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Machulda M, Lowe VJ, Mielke MM, Roberts RO, Gunter JL, Senjem ML, Geda YE, Rocca WA, Petersen RC, Jack CR. Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study. Neurology. PMID 26911640 DOI: 10.1212/WNL.0000000000002490  0.56
2016 White WM, Mielke MM, Araoz PA, Lahr BD, Bailey KR, Jayachandran M, Miller VM, Garovic VD. A history of preeclampsia is associated with a risk for coronary artery calcification three decades later. American Journal of Obstetrics and Gynecology. PMID 26874301 DOI: 10.1016/j.ajog.2016.02.003  0.56
2016 Gonzalez CE, Venkatraman VK, An Y, Landman BA, Davatzikos C, Ratnam Bandaru VV, Haughey NJ, Ferrucci L, Mielke MM, Resnick SM. Peripheral sphingolipids are associated with variation in white matter microstructure in older adults Neurobiology of Aging. 43: 156-163. DOI: 10.1016/j.neurobiolaging.2016.04.008  0.56
2015 Mielke MM, Machulda MM, Hagen CE, Christianson TJ, Roberts RO, Knopman DS, Vemuri P, Lowe VJ, Kremers WK, Jack CR, Petersen RC. Influence of amyloid and apolipoprotein E on cognitive performance in a late middle-aged cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26602629 DOI: 10.1016/j.jalz.2015.09.010  0.56
2015 Jack CR, Therneau TM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Mielke MM, Vemuri P, Roberts RO, Machulda MM, Senjem ML, Gunter JL, Rocca WA, Petersen RC. Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study. The Lancet. Neurology. PMID 26597325 DOI: 10.1016/S1474-4422(15)00323-3  0.56
2015 Knopman DS, Beiser A, Machulda MM, Fields J, Roberts RO, Pankratz VS, Aakre J, Cha RH, Rocca WA, Mielke MM, Boeve BF, Devine S, Ivnik RJ, Au R, Auerbach S, et al. Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging. Neurology. 85: 1712-21. PMID 26453643 DOI: 10.1212/WNL.0000000000002100  0.56
2015 Roberts RO, Aakre JA, Cha RH, Kremers WK, Mielke MM, Velgos SN, Geda YE, Knopman DS, Petersen RC. Association of Pancreatic Polypeptide with Mild Cognitive Impairment Varies by APOE ε4 Allele. Frontiers in Aging Neuroscience. 7: 172. PMID 26441635 DOI: 10.3389/fnagi.2015.00172  0.56
2015 Knopman DS, Jack CR, Lundt ES, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Machulda MM, Roberts RO, Boeve BF, Jones DT, et al. Role of β-Amyloidosis and Neurodegeneration in Subsequent Imaging Changes in Mild Cognitive Impairment. Jama Neurology. 1-9. PMID 26437123 DOI: 10.1001/jamaneurol.2015.2323  0.56
2015 Rabin LA, Smart CM, Crane PK, Amariglio RE, Berman LM, Boada M, Buckley RF, Chételat G, Dubois B, Ellis KA, Gifford KA, Jefferson AL, Jessen F, Katz MJ, Lipton RB, ... ... Mielke MM, et al. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures used Across 19 International Research Studies. Journal of Alzheimer's Disease : Jad. PMID 26402085 DOI: 10.3233/JAD-150154  0.56
2015 Peterlin BL, Mielke MM, Dickens AM, Chatterjee S, Dash P, Alexander G, Vieira RV, Bandaru VV, Dorskind JM, Tietjen GE, Haughey NH. Interictal, circulating sphingolipids in women with episodic migraine: A case-control study. Neurology. PMID 26354990 DOI: 10.1212/WNL.0000000000002004  0.56
2015 Vassilaki M, Aakre JA, Cha RH, Kremers WK, St Sauver JL, Mielke MM, Geda YE, Machulda MM, Knopman DS, Petersen RC, Roberts RO. Multimorbidity and Risk of Mild Cognitive Impairment. Journal of the American Geriatrics Society. 63: 1783-90. PMID 26311270 DOI: 10.1111/jgs.13612  0.56
2015 Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ. Demographic and clinical variables affecting mid- to late-life trajectories of plasma ceramide and dihydroceramide species. Aging Cell. PMID 26193443 DOI: 10.1111/acel.12369  0.56
2015 Mielke MM, Machulda MM, Hagen CE, Edwards KK, Roberts RO, Pankratz VS, Knopman DS, Jack CR, Petersen RC. Performance of the CogState computerized battery in the Mayo Clinic Study on Aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25858683 DOI: 10.1016/j.jalz.2015.01.008  0.56
2015 Roberts RO, Cha RH, Mielke MM, Geda YE, Boeve BF, Machulda MM, Knopman DS, Petersen RC. Risk and protective factors for cognitive impairment in persons aged 85 years and older. Neurology. 84: 1854-61. PMID 25854867 DOI: 10.1212/WNL.0000000000001537  0.56
2015 Pankratz VS, Roberts RO, Mielke MM, Knopman DS, Jack CR, Geda YE, Rocca WA, Petersen RC. Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. Neurology. 84: 1433-42. PMID 25788555 DOI: 10.1212/WNL.0000000000001437  0.56
2015 Vassilaki M, Cha RH, Aakre JA, Therneau TM, Geda YE, Mielke MM, Knopman DS, Petersen RC, Roberts RO. Mortality in mild cognitive impairment varies by subtype, sex, and lifestyle factors: the Mayo Clinic Study of Aging. Journal of Alzheimer's Disease : Jad. 45: 1237-45. PMID 25697699 DOI: 10.3233/JAD-143078  0.56
2015 Pink A, Stokin GB, Bartley MM, Roberts RO, Sochor O, Machulda MM, Krell-Roesch J, Knopman DS, Acosta JI, Christianson TJ, Pankratz VS, Mielke MM, Petersen RC, Geda YE. Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. Neurology. 84: 935-43. PMID 25653291 DOI: 10.1212/WNL.0000000000001307  0.56
2015 Dickens AM, Anthony DC, Deutsch R, Mielke MM, Claridge TD, Grant I, Franklin D, Rosario D, Marcotte T, Letendre S, McArthur JC, Haughey NJ. Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients. Aids (London, England). 29: 559-69. PMID 25611149 DOI: 10.1097/QAD.0000000000000580  0.56
2015 Vemuri P, Lesnick TG, Przybelski SA, Knopman DS, Preboske GM, Kantarci K, Raman MR, Machulda MM, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Rocca WA, Roberts RO, Petersen RC, et al. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain : a Journal of Neurology. 138: 761-71. PMID 25595145 DOI: 10.1093/brain/awu393  0.56
2015 Mielke MM, Bandaru VV, Han D, An Y, Resnick SM, Ferrucci L, Haughey NJ. Factors affecting longitudinal trajectories of plasma sphingomyelins: the Baltimore Longitudinal Study of Aging. Aging Cell. 14: 112-21. PMID 25345489 DOI: 10.1111/acel.12275  0.56
2015 Nowrangi MA, Okonkwo O, Lyketsos C, Oishi K, Mori S, Albert M, Mielke MM. Atlas-based diffusion tensor imaging correlates of executive function. Journal of Alzheimer's Disease : Jad. 44: 585-98. PMID 25318544 DOI: 10.3233/JAD-141937  0.56
2014 Mielke MM, Weigand SD, Wiste HJ, Vemuri P, Machulda MM, Knopman DS, Lowe V, Roberts RO, Kantarci K, Rocca WA, Jack CR, Petersen RC. Independent comparison of CogState computerized testing and a standard cognitive battery with neuroimaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 779-89. PMID 25458308 DOI: 10.1016/j.jalz.2014.09.001  0.56
2014 Jack CR, Wiste HJ, Weigand SD, Rocca WA, Knopman DS, Mielke MM, Lowe VJ, Senjem ML, Gunter JL, Preboske GM, Pankratz VS, Vemuri P, Petersen RC. Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study. The Lancet. Neurology. 13: 997-1005. PMID 25201514 DOI: 10.1016/S1474-4422(14)70194-2  0.56
2014 Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR. Association of lifetime intellectual enrichment with cognitive decline in the older population. Jama Neurology. 71: 1017-24. PMID 25054282 DOI: 10.1001/jamaneurol.2014.963  0.56
2014 Rocca WA, Mielke MM, Vemuri P, Miller VM. Sex and gender differences in the causes of dementia: a narrative review. Maturitas. 79: 196-201. PMID 24954700 DOI: 10.1016/j.maturitas.2014.05.008  0.56
2014 Mielke MM, Haughey NJ, Bandaru VV, Zetterberg H, Blennow K, Andreasson U, Johnson SC, Gleason CE, Blazel HM, Puglielli L, Sager MA, Asthana S, Carlsson CM. Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease. Neurobiology of Aging. 35: 2486-94. PMID 24952994 DOI: 10.1016/j.neurobiolaging.2014.05.019  0.56
2014 Knopman DS, Roberts RO, Pankratz VS, Cha RH, Rocca WA, Mielke MM, Boeve BF, Tangalos EG, Ivnik RJ, Geda YE, Petersen RC. Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging. American Journal of Epidemiology. 180: 414-23. PMID 24859276 DOI: 10.1093/aje/kwu103  0.56
2014 Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 844-52. PMID 24798886 DOI: 10.1016/j.jalz.2014.01.001  0.56
2014 Nicholson AM, Finch NA, Thomas CS, Wojtas A, Rutherford NJ, Mielke MM, Roberts RO, Boeve BF, Knopman DS, Petersen RC, Rademakers R. Progranulin protein levels are differently regulated in plasma and CSF. Neurology. 82: 1871-8. PMID 24771538 DOI: 10.1212/WNL.0000000000000445  0.56
2014 Jack CR, Wiste HJ, Knopman DS, Vemuri P, Mielke MM, Weigand SD, Senjem ML, Gunter JL, Lowe V, Gregg BE, Pankratz VS, Petersen RC. Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration. Neurology. 82: 1605-12. PMID 24706010 DOI: 10.1212/WNL.0000000000000386  0.56
2014 Knopman DS, Jack CR, Wiste HJ, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. Neurobiology of Aging. 35: 2096-106. PMID 24702820 DOI: 10.1016/j.neurobiolaging.2014.03.006  0.56
2014 Geda YE, Roberts RO, Mielke MM, Knopman DS, Christianson TJ, Pankratz VS, Boeve BF, Sochor O, Tangalos EG, Petersen RC, Rocca WA. Baseline neuropsychiatric symptoms and the risk of incident mild cognitive impairment: a population-based study. The American Journal of Psychiatry. 171: 572-81. PMID 24700290 DOI: 10.1176/appi.ajp.2014.13060821  0.56
2014 Roberts RO, Knopman DS, Cha RH, Mielke MM, Pankratz VS, Boeve BF, Kantarci K, Geda YE, Jack CR, Petersen RC, Lowe VJ. Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 759-64. PMID 24652830 DOI: 10.2967/jnumed.113.132647  0.56
2014 Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, Senjem ML, Pankratz VS, Geda YE, Boeve BF, Ivnik RJ, Rocca WA, Petersen RC, Jack CR. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology. 82: 1132-41. PMID 24647028 DOI: 10.1212/WNL.0000000000000269  0.56
2014 Singh B, Mielke MM, Parsaik AK, Cha RH, Roberts RO, Scanlon PD, Geda YE, Christianson TJ, Pankratz VS, Petersen RC. A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment. Jama Neurology. 71: 581-8. PMID 24637951 DOI: 10.1001/jamaneurol.2014.94  0.56
2014 Mielke MM, Maetzler W. A 'bird's eye' view on the current status and potential benefits of blood biomarkers for Parkinson's disease. Biomarkers in Medicine. 8: 225-7. PMID 24521018 DOI: 10.2217/bmm.13.139  0.56
2014 Mielke MM, Vemuri P, Rocca WA. Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences. Clinical Epidemiology. 6: 37-48. PMID 24470773 DOI: 10.2147/CLEP.S37929  0.56
2014 Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology. 82: 70-6. PMID 24371306 DOI: 10.1212/01.wnl.0000438229.56094.54  0.56
2014 Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, et al. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 109-14. PMID 24365657 DOI: 10.1016/j.jalz.2013.10.007  0.56
2014 Roberts RO, Knopman DS, Mielke MM, Cha RH, Pankratz VS, Christianson TJ, Geda YE, Boeve BF, Ivnik RJ, Tangalos EG, Rocca WA, Petersen RC. Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal. Neurology. 82: 317-25. PMID 24353333 DOI: 10.1212/WNL.0000000000000055  0.56
2014 Singh B, Parsaik AK, Mielke MM, Erwin PJ, Knopman DS, Petersen RC, Roberts RO. Association of mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis. Journal of Alzheimer's Disease : Jad. 39: 271-82. PMID 24164735 DOI: 10.3233/JAD-130830  0.56
2014 Trushina E, Mielke MM. Recent advances in the application of metabolomics to Alzheimer's Disease. Biochimica Et Biophysica Acta. 1842: 1232-9. PMID 23816564 DOI: 10.1016/j.bbadis.2013.06.014  0.56
2014 Steinberg M, Hess K, Corcoran C, Mielke MM, Norton M, Breitner J, Green R, Leoutsakos J, Welsh-Bohmer K, Lyketsos C, Tschanz J. Vascular risk factors and neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study. International Journal of Geriatric Psychiatry. 29: 153-9. PMID 23681754 DOI: 10.1002/gps.3980  0.56
2014 Roberts RO, Knopman DS, Geda YE, Cha RH, Pankratz VS, Baertlein L, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Association of diabetes with amnestic and nonamnestic mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 18-26. PMID 23562428 DOI: 10.1016/j.jalz.2013.01.001  0.56
2013 Gustafson DR, Mielke MM, Tien PC, Valcour V, Cohen M, Anastos K, Liu C, Pearce L, Golub ET, Minkoff H, Crystal HA. Anthropometric measures and cognition in middle-aged HIV-infected and uninfected women. The Women's Interagency HIV Study. Journal of Neurovirology. 19: 574-85. PMID 24338243 DOI: 10.1007/s13365-013-0219-1  0.56
2013 Saleem M, Ratnam Bandaru VV, Herrmann N, Swardfager W, Mielke MM, Oh PI, Shammi P, Kiss A, Haughey NJ, Rovinski R, Lanctôt KL. Ceramides predict verbal memory performance in coronary artery disease patients undertaking exercise: a prospective cohort pilot study. Bmc Geriatrics. 13: 135. PMID 24330446 DOI: 10.1186/1471-2318-13-135  0.56
2013 Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Rockwood K, Xiao S, Li J, Li X, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carrière I, ... ... Mielke MM, et al. COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups. Bmc Neurology. 13: 165. PMID 24195705 DOI: 10.1186/1471-2377-13-165  0.56
2013 Singh B, Parsaik AK, Mielke MM, Roberts RO, Scanlon PD, Geda YE, Pankratz VS, Christianson T, Yawn BP, Petersen RC. Chronic obstructive pulmonary disease and association with mild cognitive impairment: the Mayo Clinic Study of Aging. Mayo Clinic Proceedings. 88: 1222-30. PMID 24182702 DOI: 10.1016/j.mayocp.2013.08.012  0.56
2013 Jack CR, Wiste HJ, Weigand SD, Knopman DS, Lowe V, Vemuri P, Mielke MM, Jones DT, Senjem ML, Gunter JL, Gregg BE, Pankratz VS, Petersen RC. Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity. Neurology. 81: 1732-40. PMID 24132377 DOI: 10.1212/01.wnl.0000435556.21319.e4  0.56
2013 McDade EM, Boot BP, Christianson TJ, Pankratz VS, Boeve BF, Ferman TJ, Bieniek K, Hollman JH, Roberts RO, Mielke MM, Knopman DS, Petersen RC. Subtle gait changes in patients with REM sleep behavior disorder. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1847-53. PMID 24130124 DOI: 10.1002/mds.25653  0.56
2013 Mielke MM, Maetzler W, Haughey NJ, Bandaru VV, Savica R, Deuschle C, Gasser T, Hauser AK, Gräber-Sultan S, Schleicher E, Berg D, Liepelt-Scarfone I. Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study. Plos One. 8: e73094. PMID 24058461 DOI: 10.1371/journal.pone.0073094  0.56
2013 Machulda MM, Pankratz VS, Christianson TJ, Ivnik RJ, Mielke MM, Roberts RO, Knopman DS, Boeve BF, Petersen RC. Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the Mayo Clinic Study of Aging. The Clinical Neuropsychologist. 27: 1247-64. PMID 24041121 DOI: 10.1080/13854046.2013.836567  0.56
2013 Bandaru VV, Mielke MM, Sacktor N, McArthur JC, Grant I, Letendre S, Chang L, Wojna V, Pardo C, Calabresi P, Munsaka S, Haughey NJ. A lipid storage-like disorder contributes to cognitive decline in HIV-infected subjects. Neurology. 81: 1492-9. PMID 24027056 DOI: 10.1212/WNL.0b013e3182a9565e  0.56
2013 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Selective worsening of brain injury biomarker abnormalities in cognitively normal elderly persons with β-amyloidosis. Jama Neurology. 70: 1030-8. PMID 23797806 DOI: 10.1001/jamaneurol.2013.182  0.56
2013 Trushina E, Dutta T, Persson XM, Mielke MM, Petersen RC. Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics. Plos One. 8: e63644. PMID 23700429 DOI: 10.1371/journal.pone.0063644  0.56
2013 Miller VM, Garovic VD, Kantarci K, Barnes JN, Jayachandran M, Mielke MM, Joyner MJ, Shuster LT, Rocca WA. Sex-specific risk of cardiovascular disease and cognitive decline: pregnancy and menopause. Biology of Sex Differences. 4: 6. PMID 23537114 DOI: 10.1186/2042-6410-4-6  0.56
2013 Jack CR, Wiste HJ, Lesnick TG, Weigand SD, Knopman DS, Vemuri P, Pankratz VS, Senjem ML, Gunter JL, Mielke MM, Lowe VJ, Boeve BF, Petersen RC. Brain β-amyloid load approaches a plateau. Neurology. 80: 890-6. PMID 23446680 DOI: 10.1212/WNL.0b013e3182840bbe  0.56
2013 Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC. Brain injury biomarkers are not dependent on β-amyloid in normal elderly. Annals of Neurology. 73: 472-80. PMID 23424032 DOI: 10.1002/ana.23816  0.56
2013 Roberts RO, Geda YE, Knopman DS, Cha RH, Pankratz VS, Boeve BF, Tangalos EG, Ivnik RJ, Mielke MM, Petersen RC. Cardiac disease associated with increased risk of nonamnestic cognitive impairment: stronger effect on women. Jama Neurology. 70: 374-82. PMID 23358884 DOI: 10.1001/jamaneurol.2013.607  0.56
2013 Mielke MM, Roberts RO, Savica R, Cha R, Drubach DI, Christianson T, Pankratz VS, Geda YE, Machulda MM, Ivnik RJ, Knopman DS, Boeve BF, Rocca WA, Petersen RC. Assessing the temporal relationship between cognition and gait: slow gait predicts cognitive decline in the Mayo Clinic Study of Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 929-37. PMID 23250002 DOI: 10.1093/gerona/gls256  0.56
2013 Geda YE, Ragossnig M, Roberts LA, Roberts RO, Pankratz VS, Christianson TJ, Mielke MM, Levine JA, Boeve BF, Sochor O, Tangalos EG, Knopman DS, Petersen RC. Caloric intake, aging, and mild cognitive impairment: a population-based study. Journal of Alzheimer's Disease : Jad. 34: 501-7. PMID 23234878 DOI: 10.3233/JAD-121270  0.56
2012 Mielke MM, Haughey NJ. Could plasma sphingolipids be diagnostic or prognostic biomarkers for Alzheimer's disease? Clinical Lipidology. 7: 525-536. PMID 23606909 DOI: 10.2217/clp.12.59  0.56
2012 Mielke MM, Montine T, Khachaturian AS. Vascular diseases: one pathway toward new conceptual models of dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: S69-70. PMID 23021623 DOI: 10.1016/j.jalz.2012.09.001  0.56
2012 Mielke MM, Wiste HJ, Weigand SD, Knopman DS, Lowe VJ, Roberts RO, Geda YE, Swenson-Dravis DM, Boeve BF, Senjem ML, Vemuri P, Petersen RC, Jack CR. Indicators of amyloid burden in a population-based study of cognitively normal elderly. Neurology. 79: 1570-7. PMID 22972644 DOI: 10.1212/WNL.0b013e31826e2696  0.56
2012 Mielke MM, Bandaru VV, Haughey NJ, Xia J, Fried LP, Yasar S, Albert M, Varma V, Harris G, Schneider EB, Rabins PV, Bandeen-Roche K, Lyketsos CG, Carlson MC. Serum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II. Neurology. 79: 633-41. PMID 22815558 DOI: 10.1212/WNL.0b013e318264e380  0.56
2012 Khachaturian AS, Mielke MM, Khachaturian ZS. Biomarker development: a population-level perspective. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 247-9. PMID 22748935 DOI: 10.1016/j.jalz.2012.06.002  0.56
2012 Leoutsakos JM, Han D, Mielke MM, Forrester SN, Tschanz JT, Corcoran CD, Green RC, Norton MC, Welsh-Bohmer KA, Lyketsos CG. Effects of general medical health on Alzheimer's progression: the Cache County Dementia Progression Study. International Psychogeriatrics / Ipa. 24: 1561-70. PMID 22687143 DOI: 10.1017/S104161021200049X  0.56
2012 Mielke MM, Okonkwo OC, Oishi K, Mori S, Tighe S, Miller MI, Ceritoglu C, Brown T, Albert M, Lyketsos CG. Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 105-13. PMID 22404852 DOI: 10.1016/j.jalz.2011.05.2416  0.56
2012 Rosenberg PB, Mielke MM, Han D, Leoutsakos JS, Lyketsos CG, Rabins PV, Zandi PP, Breitner JC, Norton MC, Welsh-Bohmer KA, Zuckerman IH, Rattinger GB, Green RC, Corcoran C, Tschanz JT. The association of psychotropic medication use with the cognitive, functional, and neuropsychiatric trajectory of Alzheimer's disease. International Journal of Geriatric Psychiatry. 27: 1248-57. PMID 22374884 DOI: 10.1002/gps.3769  0.56
2012 Mielke MM, Leoutsakos JM, Corcoran CD, Green RC, Norton MC, Welsh-Bohmer KA, Tschanz JT, Lyketsos CG. Effects of Food and Drug Administration-approved medications for Alzheimer's disease on clinical progression. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 180-7. PMID 22301194 DOI: 10.1016/j.jalz.2011.02.011  0.56
2011 Mielke MM, Haughey NJ, Bandaru VV, Weinberg DD, Darby E, Zaidi N, Pavlik V, Doody RS, Lyketsos CG. Plasma sphingomyelins are associated with cognitive progression in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 259-69. PMID 21841258 DOI: 10.3233/JAD-2011-110405  0.56
2011 Gracia-Garcia P, Rao V, Haughey NJ, Ratnam Banduru VV, Smith G, Rosenberg PB, Lobo A, Lyketsos CG, Mielke MM. Elevated plasma ceramides in depression. The Journal of Neuropsychiatry and Clinical Neurosciences. 23: 215-8. PMID 21677254 DOI: 10.1176/appi.neuropsych.23.2.215  0.56
2011 Tschanz JT, Corcoran CD, Schwartz S, Treiber K, Green RC, Norton MC, Mielke MM, Piercy K, Steinberg M, Rabins PV, Leoutsakos JM, Welsh-Bohmer KA, Breitner JC, Lyketsos CG. Progression of cognitive, functional, and neuropsychiatric symptom domains in a population cohort with Alzheimer dementia: the Cache County Dementia Progression study. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 19: 532-42. PMID 21606896 DOI: 10.1097/JGP.0b013e3181faec23  0.56
2011 Mielke MM, Leoutsakos JM, Tschanz JT, Green RC, Tripodis Y, Corcoran CD, Norton MC, Lyketsos CG. Interaction between vascular factors and the APOE ε4 allele in predicting rate of progression in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 26: 127-34. PMID 21593560 DOI: 10.3233/JAD-2011-110086  0.56
2011 Okonkwo OC, Mielke MM, Griffith HR, Moghekar AR, O'Brien RJ, Shaw LM, Trojanowski JQ, Albert MS. Cerebrospinal fluid profiles and prospective course and outcome in patients with amnestic mild cognitive impairment. Archives of Neurology. 68: 113-9. PMID 21220682 DOI: 10.1001/archneurol.2010.334  0.56
2010 Mielke MM, Bandaru VV, McArthur JC, Chu M, Haughey NJ. Disturbance in cerebral spinal fluid sphingolipid content is associated with memory impairment in subjects infected with the human immunodeficiency virus. Journal of Neurovirology. 16: 445-56. PMID 21087113 DOI: 10.3109/13550284.2010.525599  0.56
2010 Mielke MM, Zandi PP, Shao H, Waern M, Östling S, Guo X, Björkelund C, Lissner L, Skoog I, Gustafson DR. The 32-year relationship between cholesterol and dementia from midlife to late life. Neurology. 75: 1888-95. PMID 21068429 DOI: 10.1212/WNL.0b013e3181feb2bf  0.56
2010 Mielke MM, Haughey NJ, Ratnam Bandaru VV, Schech S, Carrick R, Carlson MC, Mori S, Miller MI, Ceritoglu C, Brown T, Albert M, Lyketsos CG. Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 378-85. PMID 20813340 DOI: 10.1016/j.jalz.2010.03.014  0.56
2010 Oh ES, Mielke MM, Rosenberg PB, Jain A, Fedarko NS, Lyketsos CG, Mehta PD. Comparison of conventional ELISA with electrochemiluminescence technology for detection of amyloid-β in plasma. Journal of Alzheimer's Disease : Jad. 21: 769-73. PMID 20634583 DOI: 10.3233/JAD-2010-100456  0.56
2010 Okonkwo OC, Alosco ML, Griffith HR, Mielke MM, Shaw LM, Trojanowski JQ, Tremont G. Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease. Archives of Neurology. 67: 688-96. PMID 20558388 DOI: 10.1001/archneurol.2010.118  0.56
2010 Rao V, Bertrand M, Rosenberg P, Makley M, Schretlen DJ, Brandt J, Mielke MM. Predictors of new-onset depression after mild traumatic brain injury. The Journal of Neuropsychiatry and Clinical Neurosciences. 22: 100-4. PMID 20160216 DOI: 10.1176/appi.neuropsych.22.1.100  0.56
2010 Ewers M, Mielke MM, Hampel H. Blood-based biomarkers of microvascular pathology in Alzheimer's disease. Experimental Gerontology. 45: 75-9. PMID 19782124 DOI: 10.1016/j.exger.2009.09.005  0.56
2010 Mielke MM, Bandaru VV, Haughey NJ, Rabins PV, Lyketsos CG, Carlson MC. Serum sphingomyelins and ceramides are early predictors of memory impairment. Neurobiology of Aging. 31: 17-24. PMID 18455839 DOI: 10.1016/j.neurobiolaging.2008.03.011  0.56
2008 Lyketsos CG, Szekely CA, Mielke MM, Rosenberg PB, Zandi PP. Developing new treatments for Alzheimer's disease: the who, what, when, and how of biomarker-guided therapies. International Psychogeriatrics / Ipa. 20: 871-89. PMID 18498669 DOI: 10.1017/S1041610208007382  0.56
2007 Morgan MD, Mielke MM, O'Brien R, Troncoso JC, Zonderman AB, Lyketsos CG. Rates of depression in individuals with pathologic but not clinical Alzheimer disease are lower than those in individuals without the disease: findings from the Baltimore Longitudinal Study on Aging (BLSA). Alzheimer Disease and Associated Disorders. 21: 199-204. PMID 17804951 DOI: 10.1097/WAD.0b013e3181461932  0.56
2006 Mielke MM, Zandi PP. Hematologic risk factors of vascular disease and their relation to dementia. Dementia and Geriatric Cognitive Disorders. 21: 335-52. PMID 16508297 DOI: 10.1159/000091789  0.56
2006 Mielke MM, Zandi PP, Blennow K, Gustafson D, Sjögren M, Rosengren L, Skoog I. Low serum potassium in mid life associated with decreased cerebrospinal fluid Abeta42 in late life. Alzheimer Disease and Associated Disorders. 20: 30-6. PMID 16493233 DOI: 10.1097/01.wad.0000201848.67954.7d  0.56
2006 Rosenberg PB, Mielke MM, Samus QM, Rosenblatt A, Baker A, Brandt J, Rabins PV, Lyketsos CG. Transition to nursing home from assisted living is not associated with dementia or dementia-related problem behaviors. Journal of the American Medical Directors Association. 7: 73-8. PMID 16461247 DOI: 10.1016/j.jamda.2005.06.003  0.56
2005 Mielke MM, Zandi PP, Sjögren M, Gustafson D, Ostling S, Steen B, Skoog I. High total cholesterol levels in late life associated with a reduced risk of dementia. Neurology. 64: 1689-95. PMID 15911792 DOI: 10.1212/01.WNL.0000161870.78572.A5  0.56
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