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Jorge E. Galan - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Microbiology Biology
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204 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Guo E, Chou SZ, Lara-Tejero M, Galán JE. Cryo-EM structure of the bacterial effector protein SipA bound to F-actin reveals a unique mechanism for filament stabilization. Biorxiv : the Preprint Server For Biology. PMID 38187563 DOI: 10.1101/2023.12.21.572903  0.808
2023 Lian H, Park D, Chen M, Schueder F, Lara-Tejero M, Liu J, Galán JE. Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella. Nature Microbiology. PMID 37640963 DOI: 10.1038/s41564-023-01459-y  0.829
2022 Soto JE, Galán JE, Lara-Tejero M. Assembly and architecture of the type III secretion sorting platform. Proceedings of the National Academy of Sciences of the United States of America. 119: e2218010119. PMID 36512499 DOI: 10.1073/pnas.2218010119  0.735
2022 Chang SJ, Hsu YT, Chen Y, Lin YY, Lara-Tejero M, Galan JE. Typhoid toxin sorting and exocytic transport from Typhi infected cells. Elife. 11. PMID 35579416 DOI: 10.7554/eLife.78561  0.728
2021 Guo EZ, Galán JE. Cryo-EM structure of the needle filament tip complex of the type III secretion injectisome. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34706941 DOI: 10.1073/pnas.2114552118  0.79
2021 Galán JE. Salmonella Typhimurium and inflammation: a pathogen-centric affair. Nature Reviews. Microbiology. PMID 34012042 DOI: 10.1038/s41579-021-00561-4  0.361
2021 Lian H, Jiang K, Tong M, Chen Z, Liu X, Galán JE, Gao X. The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response. Nature Microbiology. PMID 33603205 DOI: 10.1038/s41564-021-00866-3  0.376
2020 Chen M, Sun H, Boot M, Shao L, Chang SJ, Wang W, Lam TT, Lara-Tejero M, Rego EH, Galán JE. Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against . Science (New York, N.Y.). 369: 450-455. PMID 32703879 DOI: 10.1126/Science.Aaz1333  0.77
2020 Geiger T, Lara-Tejero M, Xiong Y, Galán JE. Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase. Elife. 9. PMID 31958059 DOI: 10.7554/Elife.53473  0.734
2020 Geiger T, Lara-Tejero M, Xiong Y, Galán JE. Author response: Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase Elife. DOI: 10.7554/Elife.53473.Sa2  0.669
2019 Bleves S, Galán JE, Llosa M. Bacterial injection machines: Evolutionary diverse but functionally convergent. Cellular Microbiology. e13157. PMID 31891220 DOI: 10.1111/Cmi.13157  0.511
2019 Butan C, Lara-Tejero M, Li W, Liu J, Galán JE. High-resolution view of the type III secretion export apparatus in situ reveals membrane remodeling and a secretion pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 31744874 DOI: 10.1073/Pnas.1916331116  0.757
2019 Fowler CC, Stack G, Jiao X, Lara-Tejero M, Galán JE. Alternate subunit assembly diversifies the function of a bacterial toxin. Nature Communications. 10: 3684. PMID 31417089 DOI: 10.1038/S41467-019-11592-0  0.744
2019 Gibani MM, Jones E, Barton A, Jin C, Meek J, Camara S, Galal U, Heinz E, Rosenberg-Hasson Y, Obermoser G, Jones C, Campbell D, Black C, Thomaides-Brears H, Darlow C, et al. Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. Nature Medicine. PMID 31270506 DOI: 10.1038/S41591-019-0505-4  0.724
2019 Guo EZ, Desrosiers DC, Zalesak J, Tolchard J, Berbon M, Habenstein B, Marlovits T, Loquet A, Galán JE. A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion. Plos Biology. 17: e3000351. PMID 31260457 DOI: 10.1371/journal.pbio.3000351  0.805
2019 Galán JE. Reconfiguration of a bacterial transport system generates a reverse gear. Nature. 569: 44-45. PMID 31036968 DOI: 10.1038/D41586-019-01320-5  0.482
2019 Zhu S, Schniederberend M, Zhitnitsky D, Jain R, Galán JE, Kazmierczak BI, Liu J. In situ structures of polar and lateral flagella revealed by cryo-electron tomography. Journal of Bacteriology. PMID 31010901 DOI: 10.1128/Jb.00117-19  0.408
2019 Chang SJ, Jin SC, Jiao X, Galán JE. Unique features in the intracellular transport of typhoid toxin revealed by a genome-wide screen. Plos Pathogens. 15: e1007704. PMID 30951565 DOI: 10.1371/Journal.Ppat.1007704  0.392
2019 Lara-Tejero M, Galán JE. The Injectisome, a Complex Nanomachine for Protein Injection into Mammalian Cells. Ecosal Plus. 8. PMID 30942149 DOI: 10.1128/ecosalplus.ESP-0039-2018  0.765
2019 Lara-Tejero M, Qin Z, Hu B, Butan C, Liu J, Galán JE. Role of SpaO in the assembly of the sorting platform of a Salmonella type III secretion system. Plos Pathogens. 15: e1007565. PMID 30668610 DOI: 10.1371/Journal.Ppat.1007565  0.752
2019 Guo EZ, Desrosiers DC, Zalesak J, Tolchard J, Berbon M, Habenstein B, Marlovits T, Loquet A, Galán JE. A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion Plos Biology. 17. DOI: 10.2210/Pdb6Off/Pdb  0.519
2018 Park D, Lara-Tejero M, Waxham MN, Li W, Hu B, Galán JE, Liu J. Visualization of the type III secretion mediated -host cell interface using cryo-electron tomography. Elife. 7. PMID 30281019 DOI: 10.7554/Elife.39514  0.782
2018 Geiger T, Pazos M, Lara-Tejero M, Vollmer W, Galán JE. Peptidoglycan editing by a specific LD-transpeptidase controls the muramidase-dependent secretion of typhoid toxin. Nature Microbiology. PMID 30250245 DOI: 10.1038/S41564-018-0248-X  0.779
2018 Sun H, Kamanova J, Lara-Tejero M, Galán JE. Salmonella stimulates pro-inflammatory signalling through p21-activated kinases bypassing innate immune receptors. Nature Microbiology. PMID 30224799 DOI: 10.1038/S41564-018-0246-Z  0.744
2018 Kato J, Dey S, Soto JE, Butan C, Wilkinson MC, De Guzman RN, Galan JE. A protein secreted by the type III secretion system controls needle filament assembly. Elife. 7. PMID 30015613 DOI: 10.7554/Elife.35886  0.464
2018 Galán JE, Waksman G. Protein-Injection Machines in Bacteria. Cell. 172: 1306-1318. PMID 29522749 DOI: 10.1016/J.Cell.2018.01.034  0.484
2018 Fowler CC, Galán JE. Decoding a Salmonella Typhi Regulatory Network that Controls Typhoid Toxin Expression within Human Cells. Cell Host & Microbe. 23: 65-76.e6. PMID 29324231 DOI: 10.1016/J.Chom.2017.12.001  0.446
2018 Park D, Lara-Tejero M, Waxham MN, Li W, Hu B, Galán JE, Liu J. Author response: Visualization of the type III secretion mediated Salmonella–host cell interface using cryo-electron tomography Elife. DOI: 10.7554/Elife.39514.018  0.673
2018 Kato J, Dey S, Soto JE, Butan C, Wilkinson MC, Guzman RND, Galan JE. Author response: A protein secreted by the Salmonella type III secretion system controls needle filament assembly Elife. DOI: 10.7554/Elife.35886.029  0.394
2017 Gao X, Deng L, Stack G, Yu H, Chen X, Naito-Matsui Y, Varki A, Galán JE. Author Correction: Evolution of host adaptation in the Salmonella typhoid toxin. Nature Microbiology. PMID 29093550 DOI: 10.1038/S41564-017-0070-X  0.329
2017 Gao X, Deng L, Stack G, Yu H, Chen X, Naito-Matsui Y, Varki A, Galán JE. Evolution of host adaptation in the Salmonella typhoid toxin. Nature Microbiology. PMID 28993610 DOI: 10.1038/S41564-017-0033-2  0.469
2017 Hannemann S, Galán JE. Salmonella enterica serovar-specific transcriptional reprogramming of infected cells. Plos Pathogens. 13: e1006532. PMID 28742135 DOI: 10.1371/Journal.Ppat.1006532  0.47
2017 Spanò S, Galán JE. Taking control: hijacking of Rab GTPases by intracellular bacterial pathogens. Small Gtpases. 0. PMID 28632996 DOI: 10.1080/21541248.2017.1336192  0.806
2017 Gao B, Vorwerk H, Huber C, Lara-Tejero M, Mohr J, Goodman AL, Eisenreich W, Galán JE, Hofreuter D. Metabolic and fitness determinants for in vitro growth and intestinal colonization of the bacterial pathogen Campylobacter jejuni. Plos Biology. 15: e2001390. PMID 28542173 DOI: 10.1371/Journal.Pbio.2001390  0.713
2017 Zhang Y, Lara-Tejero M, Bewersdorf J, Galán JE. Visualization and characterization of individual type III protein secretion machines in live bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533372 DOI: 10.1073/Pnas.1705823114  0.71
2017 Hu B, Lara-Tejero M, Kong Q, Galán JE, Liu J. In Situ Molecular Architecture of the Salmonella Type III Secretion Machine. Cell. 168: 1065-1074.e10. PMID 28283062 DOI: 10.1016/J.Cell.2017.02.022  0.731
2017 Fowler CC, Chang SJ, Gao X, Geiger T, Stack G, Galán JE. Emerging insights into the biology of typhoid toxin. Current Opinion in Microbiology. 35: 70-77. PMID 28213043 DOI: 10.1016/J.Mib.2017.01.012  0.343
2016 Dietsche T, Tesfazgi Mebrhatu M, Brunner MJ, Abrusci P, Yan J, Franz-Wachtel M, Schärfe C, Zilkenat S, Grin I, Galán JE, Kohlbacher O, Lea S, Macek B, Marlovits TC, Robinson CV, et al. Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus. Plos Pathogens. 12: e1006071. PMID 27977800 DOI: 10.1371/Journal.Ppat.1006071  0.54
2016 Chang SJ, Song J, Galán JE. Receptor-Mediated Sorting of Typhoid Toxin during Its Export from Salmonella Typhi-Infected Cells. Cell Host & Microbe. 20: 682-689. PMID 27832592 DOI: 10.1016/J.Chom.2016.10.005  0.463
2016 Galán JE. Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi. Proceedings of the National Academy of Sciences of the United States of America. PMID 27222578 DOI: 10.1073/Pnas.1606335113  0.417
2016 Kamanova J, Sun H, Lara-Tejero M, Galán JE. The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members. Plos Pathogens. 12: e1005552. PMID 27058235 DOI: 10.1371/Journal.Ppat.1005552  0.731
2016 Sun H, Kamanova J, Lara-Tejero M, Galán JE. A Family of Salmonella Type III Secretion Effector Proteins Selectively Targets the NF-κB Signaling Pathway to Preserve Host Homeostasis. Plos Pathogens. 12: e1005484. PMID 26933955 DOI: 10.1371/Journal.Ppat.1005484  0.756
2016 Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, et al. Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi. Cell. 164: 827-828. PMID 26919416 DOI: 10.1016/J.Cell.2016.02.015  0.321
2016 Zilkenat S, Franz-Wachtel M, Stierhof YD, Galan JE, Macek B, Wagner S. Determination of the stoichiometry of the complete bacterial type III secretion needle complex using a combined quantitative proteomic approach. Molecular & Cellular Proteomics : McP. PMID 26900162 DOI: 10.1074/Mcp.M115.056598  0.45
2016 Spanò S, Gao X, Hannemann S, Lara-Tejero M, Galán JE. A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP. Cell Host & Microbe. 19: 216-26. PMID 26867180 DOI: 10.1016/J.Chom.2016.01.004  0.842
2016 Tsou LK, Lara-Tejero M, RoseFigura J, Zhang ZJ, Wang YC, Yount JS, Lefebre M, Dossa PD, Kato J, Guan F, Lam W, Cheng YC, Galan JE, Hang HC. Anti-bacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates. Journal of the American Chemical Society. PMID 26847396 DOI: 10.1021/Jacs.5B11575  0.756
2015 Monjarás Feria JV, Lefebre MD, Stierhof YD, Galán JE, Wagner S. Role of Autocleavage in the Function of a Type III Secretion Specificity Switch Protein in Salmonella enterica Serovar Typhimurium. Mbio. 6. PMID 26463164 DOI: 10.1128/Mbio.01459-15  0.529
2015 Kato J, Lefebre M, Galán JE. Structural Features Reminiscent of ATP-Driven Protein Translocases Are Essential for the Function of a Type III Secretion-Associated ATPase. Journal of Bacteriology. 197: 3007-14. PMID 26170413 DOI: 10.1128/Jb.00434-15  0.515
2014 Deng L, Song J, Gao X, Wang J, Yu H, Chen X, Varki N, Naito-Matsui Y, Galán JE, Varki A. Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. Cell. 159: 1290-9. PMID 25480294 DOI: 10.1016/J.Cell.2014.10.057  0.411
2014 Galán JE, Lara-Tejero M, Marlovits TC, Wagner S. Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells. Annual Review of Microbiology. 68: 415-38. PMID 25002086 DOI: 10.1146/Annurev-Micro-092412-155725  0.784
2014 Gao B, Lara-Tejero M, Lefebre M, Goodman AL, Galán JE. Novel components of the flagellar system in epsilonproteobacteria Mbio. 5. PMID 24961693 DOI: 10.1128/Mbio.01349-14  0.736
2014 Rathinavelan T, Lara-Tejero M, Lefebre M, Chatterjee S, McShan AC, Guo DC, Tang C, Galan JE, De Guzman RN. NMR model of PrgI-SipD interaction and its implications in the needle-tip assembly of the Salmonella type III secretion system. Journal of Molecular Biology. 426: 2958-69. PMID 24951833 DOI: 10.1016/J.Jmb.2014.06.009  0.72
2014 Kohler AC, Spanò S, Galán JE, Stebbins CE. Structural and enzymatic characterization of a host-specificity determinant from Salmonella. Acta Crystallographica. Section D, Biological Crystallography. 70: 384-91. PMID 24531472 DOI: 10.1107/S1399004713028393  0.444
2014 Lefebre MD, Galán JE. The inner rod protein controls substrate switching and needle length in a Salmonella type III secretion system. Proceedings of the National Academy of Sciences of the United States of America. 111: 817-22. PMID 24379359 DOI: 10.1073/Pnas.1319698111  0.498
2013 Spanò S, Galán JE. A novel anti-microbial function for a familiar Rab GTPase. Small Gtpases. 4: 252-4. PMID 24321888 DOI: 10.4161/Sgtp.27282  0.799
2013 Hannemann S, Gao B, Galán JE. Salmonella modulation of host cell gene expression promotes its intracellular growth. Plos Pathogens. 9: e1003668. PMID 24098123 DOI: 10.1371/Journal.Ppat.1003668  0.542
2013 Song J, Gao X, Galán JE. Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature. 499: 350-4. PMID 23842500 DOI: 10.1038/Nature12377  0.384
2013 Hicks SW, Galán JE. Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors. Nature Reviews. Microbiology. 11: 316-26. PMID 23588250 DOI: 10.1038/Nrmicro3009  0.531
2013 Carleton HA, Lara-Tejero M, Liu X, Galán JE. Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery. Nature Communications. 4: 1590. PMID 23481398 DOI: 10.1038/Ncomms2594  0.698
2013 Hodak H, Galán JE. A Salmonella Typhi homologue of bacteriophage muramidases controls typhoid toxin secretion. Embo Reports. 14: 95-102. PMID 23174673 DOI: 10.1038/Embor.2012.186  0.511
2012 Hofreuter D, Mohr J, Wensel O, Rademacher S, Schreiber K, Schomburg D, Gao B, Galán JE. Contribution of amino acid catabolism to the tissue specific persistence of Campylobacter jejuni in a murine colonization model. Plos One. 7: e50699. PMID 23226358 DOI: 10.1371/Journal.Pone.0050699  0.311
2012 Spanò S, Galán JE. A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science (New York, N.Y.). 338: 960-3. PMID 23162001 DOI: 10.1126/Science.1229224  0.794
2012 Zhong D, Lefebre M, Kaur K, McDowell MA, Gdowski C, Jo S, Wang Y, Benedict SH, Lea SM, Galan JE, De Guzman RN. The Salmonella type III secretion system inner rod protein PrgJ is partially folded. The Journal of Biological Chemistry. 287: 25303-11. PMID 22654099 DOI: 10.1074/Jbc.M112.381574  0.405
2012 Liu X, Gao B, Novik V, Galán JE. Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. Plos Pathogens. 8: e1002562. PMID 22412372 DOI: 10.1371/Journal.Ppat.1002562  0.666
2011 Spanò S, Liu X, Galán JE. Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella. Proceedings of the National Academy of Sciences of the United States of America. 108: 18418-23. PMID 22042847 DOI: 10.1073/Pnas.1111959108  0.807
2011 Mukherjee S, Liu X, Arasaki K, McDonough J, Galán JE, Roy CR. Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature. 477: 103-6. PMID 21822290 DOI: 10.1038/Nature10335  0.493
2011 Button JE, Galán JE. Regulation of chaperone/effector complex synthesis in a bacterial type III secretion system. Molecular Microbiology. 81: 1474-83. PMID 21801239 DOI: 10.1111/J.1365-2958.2011.07784.X  0.821
2011 Hicks SW, Charron G, Hang HC, Galán JE. Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation. Cell Host & Microbe. 10: 9-20. PMID 21767808 DOI: 10.1016/J.Chom.2011.06.003  0.553
2011 Lara-Tejero M, Kato J, Wagner S, Liu X, Galán JE. A sorting platform determines the order of protein secretion in bacterial type III systems. Science (New York, N.Y.). 331: 1188-91. PMID 21292939 DOI: 10.1126/Science.1201476  0.76
2010 Song J, Willinger T, Rongvaux A, Eynon EE, Stevens S, Manz MG, Flavell RA, Galán JE. A mouse model for the human pathogen Salmonella typhi. Cell Host & Microbe. 8: 369-76. PMID 20951970 DOI: 10.1016/J.Chom.2010.09.003  0.406
2010 Wagner S, Königsmaier L, Lara-Tejero M, Lefebre M, Marlovits TC, Galán JE. Organization and coordinated assembly of the type III secretion export apparatus. Proceedings of the National Academy of Sciences of the United States of America. 107: 17745-50. PMID 20876096 DOI: 10.1073/Pnas.1008053107  0.749
2010 Novik V, Hofreuter D, Galán JE. Identification of Campylobacter jejuni genes involved in its interaction with epithelial cells. Infection and Immunity. 78: 3540-53. PMID 20515930 DOI: 10.1128/Iai.00109-10  0.647
2010 Schraidt O, Lefebre MD, Brunner MJ, Schmied WH, Schmidt A, Radics J, Mechtler K, Galán JE, Marlovits TC. Topology and organization of the Salmonella typhimurium type III secretion needle complex components. Plos Pathogens. 6: e1000824. PMID 20368966 DOI: 10.1371/Journal.Ppat.1000824  0.488
2010 Hicks SW, Galán JE. Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases. Current Opinion in Microbiology. 13: 41-6. PMID 20036613 DOI: 10.1016/J.Mib.2009.11.008  0.507
2009 Novik V, Hofreuter D, Galán JE. Characterization of a Campylobacter jejuni VirK protein homolog as a novel virulence determinant. Infection and Immunity. 77: 5428-36. PMID 19797067 DOI: 10.1128/Iai.00528-09  0.652
2009 Du F, Galán JE. Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. Plos Pathogens. 5: e1000595. PMID 19779561 DOI: 10.1371/Journal.Ppat.1000595  0.484
2009 Bruno VM, Hannemann S, Lara-Tejero M, Flavell RA, Kleinstein SH, Galán JE. Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. Plos Pathogens. 5: e1000538. PMID 19662166 DOI: 10.1371/Journal.Ppat.1000538  0.747
2009 Galán JE. Common themes in the design and function of bacterial effectors. Cell Host & Microbe. 5: 571-9. PMID 19527884 DOI: 10.1016/J.Chom.2009.04.008  0.511
2009 Patel JC, Hueffer K, Lam TT, Galán JE. Diversification of a Salmonella virulence protein function by ubiquitin-dependent differential localization. Cell. 137: 283-94. PMID 19379694 DOI: 10.1016/J.Cell.2009.01.056  0.537
2009 Lara-Tejero M, Galán JE. Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cells. Infection and Immunity. 77: 2635-42. PMID 19364837 DOI: 10.1128/Iai.00077-09  0.785
2009 Quezada CM, Hicks SW, Galán JE, Stebbins CE. A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases. Proceedings of the National Academy of Sciences of the United States of America. 106: 4864-9. PMID 19273841 DOI: 10.1073/Pnas.0811058106  0.409
2008 Hofreuter D, Novik V, Galán JE. Metabolic diversity in Campylobacter jejuni enhances specific tissue colonization. Cell Host & Microbe. 4: 425-33. PMID 18996343 DOI: 10.1016/J.Chom.2008.10.002  0.639
2008 Patel JC, Galán JE. Investigating the function of Rho family GTPases during Salmonella/host cell interactions. Methods in Enzymology. 439: 145-58. PMID 18374162 DOI: 10.1016/S0076-6879(07)00411-9  0.441
2008 Galán JE. Energizing type III secretion machines: what is the fuel? Nature Structural & Molecular Biology. 15: 127-8. PMID 18250631 DOI: 10.1038/Nsmb0208-127  0.384
2008 Spanò S, Galán JE. A novel pathway for exotoxin delivery by an intracellular pathogen. Current Opinion in Microbiology. 11: 15-20. PMID 18243772 DOI: 10.1016/J.Mib.2007.12.002  0.8
2008 Watson RO, Galán JE. Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. Plos Pathogens. 4: e14. PMID 18225954 DOI: 10.1371/Journal.Ppat.0040014  0.684
2008 Spanò S, Ugalde JE, Galán JE. Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment. Cell Host & Microbe. 3: 30-8. PMID 18191792 DOI: 10.1016/J.Chom.2007.11.001  0.801
2008 Strachan NJ, Watson RO, Novik V, Hofreuter D, Ogden ID, Galán JE. Sexual dimorphism in campylobacteriosis. Epidemiology and Infection. 136: 1492-5. PMID 18062834 DOI: 10.1017/S0950268807009934  0.689
2007 Galán JE. SnapShot: effector proteins of type III secretion systems. Cell. 130: 192. PMID 17632065 DOI: 10.1016/J.Cell.2007.06.042  0.401
2007 Haghjoo E, Galán JE. Identification of a transcriptional regulator that controls intracellular gene expression in Salmonella Typhi. Molecular Microbiology. 64: 1549-61. PMID 17555437 DOI: 10.1111/J.1365-2958.2007.05754.X  0.81
2007 Watson RO, Novik V, Hofreuter D, Lara-Tejero M, Galán JE. A MyD88-deficient mouse model reveals a role for Nramp1 in Campylobacter jejuni infection. Infection and Immunity. 75: 1994-2003. PMID 17194808 DOI: 10.1128/Iai.01216-06  0.79
2006 Kamanaka M, Kim ST, Wan YY, Sutterwala FS, Lara-Tejero M, Galán JE, Harhaj E, Flavell RA. Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity. 25: 941-52. PMID 17137799 DOI: 10.1016/J.Immuni.2006.09.013  0.686
2006 Galán JE, Wolf-Watz H. Protein delivery into eukaryotic cells by type III secretion machines. Nature. 444: 567-73. PMID 17136086 DOI: 10.1038/Nature05272  0.559
2006 Patel JC, Galán JE. Differential activation and function of Rho GTPases during Salmonella-host cell interactions. The Journal of Cell Biology. 175: 453-63. PMID 17074883 DOI: 10.1083/Jcb.200605144  0.459
2006 Chen LM, Briones G, Donis RO, Galán JE. Optimization of the delivery of heterologous proteins by the Salmonella enterica serovar Typhimurium type III secretion system for vaccine development. Infection and Immunity. 74: 5826-33. PMID 16988261 DOI: 10.1128/Iai.00375-06  0.45
2006 Feuillet V, Medjane S, Mondor I, Demaria O, Pagni PP, Galán JE, Flavell RA, Alexopoulou L. Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria. Proceedings of the National Academy of Sciences of the United States of America. 103: 12487-92. PMID 16891416 DOI: 10.1073/Pnas.0605200103  0.421
2006 Hofreuter D, Tsai J, Watson RO, Novik V, Altman B, Benitez M, Clark C, Perbost C, Jarvie T, Du L, Galán JE. Unique features of a highly pathogenic Campylobacter jejuni strain. Infection and Immunity. 74: 4694-707. PMID 16861657 DOI: 10.1128/IAI.00210-06  0.726
2006 Marlovits TC, Kubori T, Lara-Tejero M, Thomas D, Unger VM, Galán JE. Assembly of the inner rod determines needle length in the type III secretion injectisome. Nature. 441: 637-40. PMID 16738660 DOI: 10.1038/Nature04822  0.746
2006 Lara-Tejero M, Sutterwala FS, Ogura Y, Grant EP, Bertin J, Coyle AJ, Flavell RA, Galán JE. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. The Journal of Experimental Medicine. 203: 1407-12. PMID 16717117 DOI: 10.1084/Jem.20060206  0.701
2006 Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, Bertin J, Coyle AJ, Galán JE, Askenase PW, Flavell RA. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity. 24: 317-27. PMID 16546100 DOI: 10.1016/J.Immuni.2006.02.004  0.681
2006 Briones G, Hofreuter D, Galán JE. Cre reporter system to monitor the translocation of type III secreted proteins into host cells. Infection and Immunity. 74: 1084-90. PMID 16428755 DOI: 10.1128/Iai.74.2.1084-1090.2006  0.498
2005 Akeda Y, Galán JE. Chaperone release and unfolding of substrates in type III secretion. Nature. 437: 911-5. PMID 16208377 DOI: 10.1038/Nature03992  0.494
2005 Patel JC, Rossanese OW, Galán JE. The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends in Pharmacological Sciences. 26: 564-70. PMID 16182381 DOI: 10.1016/J.Tips.2005.09.005  0.501
2005 Watson RO, Galán JE. Signal transduction in Campylobacter jejuni-induced cytokine production. Cellular Microbiology. 7: 655-65. PMID 15839895 DOI: 10.1111/J.1462-5822.2004.00498.X  0.637
2005 Galán JE. Bacterial toxins and the immune system: show me the in vivo targets. The Journal of Experimental Medicine. 201: 321-3. PMID 15699067 DOI: 10.1084/Jem.20050080  0.418
2005 Patel JC, Galán JE. Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry. Current Opinion in Microbiology. 8: 10-5. PMID 15694851 DOI: 10.1016/J.Mib.2004.09.001  0.515
2005 Galán JE, Cossart P. Host-pathogen interactions: a diversity of themes, a variety of molecular machines. Current Opinion in Microbiology. 8: 1-3. PMID 15694849 DOI: 10.1016/J.Mib.2004.12.015  0.4
2004 Jiang X, Rossanese OW, Brown NF, Kujat-Choy S, Galán JE, Finlay BB, Brumell JH. The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Molecular Microbiology. 54: 1186-98. PMID 15554961 DOI: 10.1111/J.1365-2958.2004.04344.X  0.491
2004 Marlovits TC, Kubori T, Sukhan A, Thomas DR, Galán JE, Unger VM. Structural insights into the assembly of the type III secretion needle complex. Science (New York, N.Y.). 306: 1040-2. PMID 15528446 DOI: 10.1126/Science.1102610  0.429
2004 Hueffer K, Galán JE. Salmonella-induced macrophage death: multiple mechanisms, different outcomes. Cellular Microbiology. 6: 1019-25. PMID 15469431 DOI: 10.1111/J.1462-5822.2004.00451.X  0.425
2004 Lara-Tejero M, Galán JE. A new twist in the hijacking of the actin-nucleating machinery. Molecular Cell. 15: 495-7. PMID 15327766 DOI: 10.1016/J.Molcel.2004.08.013  0.737
2004 Hernandez LD, Hueffer K, Wenk MR, Galán JE. Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (New York, N.Y.). 304: 1805-7. PMID 15205533 DOI: 10.1126/Science.1098188  0.491
2004 Haghjoo E, Galán JE. Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proceedings of the National Academy of Sciences of the United States of America. 101: 4614-9. PMID 15070766 DOI: 10.1073/Pnas.0400932101  0.839
2004 Akeda Y, Galán JE. Genetic analysis of the Salmonella enterica type III secretion-associated ATPase InvC defines discrete functional domains. Journal of Bacteriology. 186: 2402-12. PMID 15060043 DOI: 10.1128/Jb.186.8.2402-2412.2004  0.378
2004 McKinney JS, Zhang H, Kubori T, Galán JE, Altman S. Disruption of type III secretion in Salmonella enterica serovar Typhimurium by external guide sequences. Nucleic Acids Research. 32: 848-54. PMID 14762212 DOI: 10.1093/Nar/Gkh219  0.402
2004 Lee SH, Galán JE. Salmonella type III secretion-associated chaperones confer secretion-pathway specificity. Molecular Microbiology. 51: 483-95. PMID 14756788 DOI: 10.1046/J.1365-2958.2003.03840.X  0.428
2003 Hernandez LD, Pypaert M, Flavell RA, Galán JE. A Salmonella protein causes macrophage cell death by inducing autophagy. The Journal of Cell Biology. 163: 1123-31. PMID 14662750 DOI: 10.1083/Jcb.200309161  0.426
2003 Lee SH, Galán JE. InvB is a type III secretion-associated chaperone for the Salmonella enterica effector protein SopE. Journal of Bacteriology. 185: 7279-84. PMID 14645290 DOI: 10.1128/Jb.185.24.7279-7284.2003  0.379
2003 Kubori T, Galán JE. Temporal regulation of salmonella virulence effector function by proteasome-dependent protein degradation. Cell. 115: 333-42. PMID 14636560 DOI: 10.1016/S0092-8674(03)00849-3  0.538
2003 Stebbins CE, Galán JE. Priming virulence factors for delivery into the host. Nature Reviews. Molecular Cell Biology. 4: 738-43. PMID 14506477 DOI: 10.1038/Nrm1201  0.48
2003 Sukhan A, Kubori T, Galán JE. Synthesis and localization of the Salmonella SPI-1 type III secretion needle complex proteins PrgI and PrgJ. Journal of Bacteriology. 185: 3480-3. PMID 12754250 DOI: 10.1128/Jb.185.11.3480-3483.2003  0.415
2003 Evans DT, Chen LM, Gillis J, Lin KC, Harty B, Mazzara GP, Donis RO, Mansfield KG, Lifson JD, Desrosiers RC, Galán JE, Johnson RP. Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system. Journal of Virology. 77: 2400-9. PMID 12551977 DOI: 10.1128/Jvi.77.4.2400-2409.2003  0.344
2002 Carlyon JA, Chan WT, Galán J, Roos D, Fikrig E. Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation. Journal of Immunology (Baltimore, Md. : 1950). 169: 7009-18. PMID 12471136 DOI: 10.4049/Jimmunol.169.12.7009  0.396
2002 Rüssmann H, Kubori T, Sauer J, Galán JE. Molecular and functional analysis of the type III secretion signal of the Salmonella enterica InvJ protein. Molecular Microbiology. 46: 769-79. PMID 12410834 DOI: 10.1046/J.1365-2958.2002.03196.X  0.474
2002 Kubori T, Galán JE. Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cells. Journal of Bacteriology. 184: 4699-708. PMID 12169593 DOI: 10.1128/Jb.184.17.4699-4708.2002  0.514
2002 Galán JE. The cell biology of microbial infections: coming of age. The Journal of Cell Biology. 158: 387-8. PMID 12163462 DOI: 10.1083/Jcb.200206053  0.357
2002 Buchwald G, Friebel A, Galán JE, Hardt WD, Wittinghofer A, Scheffzek K. Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. The Embo Journal. 21: 3286-95. PMID 12093730 DOI: 10.1093/Emboj/Cdf329  0.462
2002 Galkin VE, Orlova A, VanLoock MS, Zhou D, Galán JE, Egelman EH. The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin. Nature Structural Biology. 9: 518-21. PMID 12055622 DOI: 10.1038/Nsb811  0.366
2002 Hughes EA, Galán JE. Immune response to Salmonella: location, location, location? Immunity. 16: 325-8. PMID 11911817 DOI: 10.1016/S1074-7613(02)00293-5  0.369
2002 Kobayashi K, Inohara N, Hernandez LD, Galán JE, Núñez G, Janeway CA, Medzhitov R, Flavell RA. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature. 416: 194-9. PMID 11894098 DOI: 10.1038/416194A  0.353
2002 Lara-Tejero M, Galán JE. Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends in Microbiology. 10: 147-52. PMID 11864825 DOI: 10.1016/S0966-842X(02)02316-8  0.765
2002 Zhou D, Galán J. Salmonella entry into host cells: the work in concert of type III secreted effector proteins. Microbes and Infection. 3: 1293-8. PMID 11755417 DOI: 10.1016/S1286-4579(01)01489-7  0.505
2002 Shams H, Poblete F, Rüssmann H, Galán JE, Donis RO. Induction of specific CD8+ memory T cells and long lasting protection following immunization with Salmonella typhimurium expressing a lymphocytic choriomeningitis MHC class I-restricted epitope. Vaccine. 20: 577-85. PMID 11672924 DOI: 10.1016/S0264-410X(01)00363-2  0.362
2001 Murli S, Watson RO, Galán JE. Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells. Cellular Microbiology. 3: 795-810. PMID 11736992 DOI: 10.1046/J.1462-5822.2001.00158.X  0.707
2001 Stebbins CE, Galán JE. Maintenance of an unfolded polypeptide by a cognate chaperone in bacterial type III secretion Nature. 414: 77-81. PMID 11689946 DOI: 10.1038/35102073  0.466
2001 Galán JE. Salmonella interactions with host cells: type III secretion at work. Annual Review of Cell and Developmental Biology. 17: 53-86. PMID 11687484 DOI: 10.1146/Annurev.Cellbio.17.1.53  0.56
2001 Stebbins CE, Galan JE. Structural mimicry in bacterial virulence Nature. 412: 701-705. PMID 11507631 DOI: 10.1038/35089000  0.472
2001 Staskawicz BJ, Mudgett MB, Dangl JL, Galan JE. Common and contrasting themes of plant and animal diseases. Science (New York, N.Y.). 292: 2285-9. PMID 11423652 DOI: 10.1126/Science.1062013  0.425
2001 Lara-Tejero M, Galán JE. CdtA, CdtB, and CdtC Form a Tripartite Complex That Is Required for Cytolethal Distending Toxin Activity Infection and Immunity. 69: 4358-4365. PMID 11401974 DOI: 10.1128/Iai.69.7.4358-4365.2001  0.721
2001 Pancetti A, Galán JE. Characterization of the mutS‐proximal region of the Salmonella typhimurium SPI‐1 identifies a group of pathogenicity island‐associated genes Fems Microbiology Letters. 197: 203-208. PMID 11313135 DOI: 10.1111/J.1574-6968.2001.Tb10604.X  0.785
2001 Colegio OR, Griffin TJ, Grindley ND, Galán JE. In vitro transposition system for efficient generation of random mutants of Campylobacter jejuni. Journal of Bacteriology. 183: 2384-8. PMID 11244083 DOI: 10.1128/Jb.183.7.2384-2388.2001  0.397
2001 Sukhan A, Kubori T, Wilson J, Galán JE. Genetic analysis of assembly of the Salmonella enterica serovar Typhimurium type III secretion-associated needle complex. Journal of Bacteriology. 183: 1159-1167. PMID 11157927 DOI: 10.1128/Jb.183.4.1159-1167.2001  0.537
2001 Zhou D, Chen LM, Hernandez L, Shears SB, Galán JE. A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalization. Molecular Microbiology. 39: 248-59. PMID 11136447 DOI: 10.1046/J.1365-2958.2001.02230.X  0.569
2000 Stebbins CE, Galán JE. Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1. Molecular Cell. 6: 1449-1460. PMID 11163217 DOI: 10.1016/S1097-2765(00)00141-6  0.488
2000 Galán JE. Alternative strategies for becoming an insider: lessons from the bacterial world. Cell. 103: 363-366. PMID 11081622 DOI: 10.1016/S0092-8674(00)00127-6  0.37
2000 Galan JE, Fu Y. Modulation of actin cytoskeleton by Salmonella GTPase activating protein SptP Methods in Enzymology. 325: 496-505. PMID 11036630 DOI: 10.1016/S0076-6879(00)25469-4  0.425
2000 Lara-Tejero M, Galan JE. A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein Science. 290: 354-357. PMID 11030657 DOI: 10.1126/Science.290.5490.354  0.74
2000 Mitra K, Zhou D, Galán JE. Biophysical characterization of SipA, an actin-binding protein from Salmonella enterica Febs Letters. 482: 81-84. PMID 11018527 DOI: 10.1016/S0014-5793(00)02040-8  0.423
2000 Kubori T, Sukhan A, Aizawa SI, Galán JE. Molecular characterization and assembly of the needle complex of the Salmonella typhimurium type III protein secretion system. Proceedings of the National Academy of Sciences of the United States of America. 97: 10225-30. PMID 10944190 DOI: 10.1073/Pnas.170128997  0.534
2000 Galan JE, Zhou D. Striking a balance: modulation of the actin cytoskeleton by Salmonella. Proceedings of the National Academy of Sciences of the United States of America. 97: 8754-61. PMID 10922031 DOI: 10.1073/Pnas.97.16.8754  0.543
2000 Eichelberg K, Galán JE. The Flagellar Sigma Factor FliA (ς28) Regulates the Expression of Salmonella Genes Associated with the Centisome 63 Type III Secretion System Infection and Immunity. 68: 2735-2743. PMID 10768967 DOI: 10.1128/Iai.68.5.2735-2743.2000  0.461
2000 Tucker SC, Galán JE. Complex function for SicA, a Salmonella enterica serovar typhimurium type III secretion-associated chaperone Journal of Bacteriology. 182: 2262-2268. PMID 10735870 DOI: 10.1128/Jb.182.8.2262-2268.2000  0.449
1999 Fu Y, Galán JE. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion Nature. 401: 293-297. PMID 10499590 DOI: 10.1038/45829  0.559
1999 Zhou D, Mooseker MS, Galán JE. An invasion-associated Salmonella protein modulates the actin-bundling activity of plastin. Proceedings of the National Academy of Sciences of the United States of America. 96: 10176-81. PMID 10468582 DOI: 10.1073/Pnas.96.18.10176  0.492
1999 Eichelberg K, Galán JE. Differential Regulation of Salmonella typhimurium Type III Secreted Proteins by Pathogenicity Island 1 (SPI-1)-Encoded Transcriptional Activators InvF and HilA Infection and Immunity. 67: 4099-4105. PMID 10417179 DOI: 10.1128/Iai.67.8.4099-4105.1999  0.505
1999 Eichelberg K, Hardt W, Galán JE. Characterization of SprA, an AraC-like transcriptional regulator encoded within the Salmonella typhimurium pathogenicity island 1. Molecular Microbiology. 33: 139-152. PMID 10411731 DOI: 10.1046/J.1365-2958.1999.01458.X  0.517
1999 Galán JE, Collmer A. Type III secretion machines: bacterial devices for protein delivery into host cells. Science (New York, N.Y.). 284: 1322-8. PMID 10334981 DOI: 10.1126/Science.284.5418.1322  0.52
1999 Chen LM, Bagrodia S, Cerione RA, Galán JE. Requirement of p21-activated kinase (PAK) for Salmonella typhimurium-induced nuclear responses. The Journal of Experimental Medicine. 189: 1479-88. PMID 10224288 DOI: 10.1084/Jem.189.9.1479  0.463
1999 Zhou D, Mooseker MS, Galán JE. Role of the S. typhimurium actin-binding protein SipA in bacterial internalization. Science (New York, N.Y.). 283: 2092-5. PMID 10092234 DOI: 10.1126/Science.283.5410.2092  0.43
1999 Galán JE. Interaction of Salmonella with host cells through the centisome 63 type III secretion system. Current Opinion in Microbiology. 2: 46-50. PMID 10047557 DOI: 10.1016/S1369-5274(99)80008-3  0.51
1999 Zhou D, Hardt W, Galán JE. Salmonella typhimurium Encodes a Putative Iron Transport System within the Centisome 63 Pathogenicity Island Infection and Immunity. 67: 1974-1981. DOI: 10.1128/Iai.67.4.1974-1981.1999  0.375
1999 Murli S, Galán JE. Interaction of Salmonella spp. with host cells Advances in Cellular and Molecular Biology of Membranes and Organelles. 6: 173-180. DOI: 10.1016/S1874-5172(99)80011-X  0.536
1998 Galan JE. Interactions of Salmonella with host cells: Encounters of the closest kind Proceedings of the National Academy of Sciences of the United States of America. 95: 14006-14008. PMID 9826642 DOI: 10.1073/Pnas.95.24.14006  0.47
1998 Rüssmann H, Shams H, Poblete F, Fu Y, Galán JE, Donis RO. Delivery of epitopes by the Salmonella type III secretion system for vaccine development. Science (New York, N.Y.). 281: 565-8. PMID 9677200 DOI: 10.1126/Science.281.5376.565  0.434
1998 Fu Y, Galán JE. Identification of a Specific Chaperone for SptP, a Substrate of the Centisome 63 Type III Secretion System of Salmonella typhimurium Journal of Bacteriology. 180: 3393-3399. PMID 9642193 DOI: 10.1128/Jb.180.13.3393-3399.1998  0.515
1998 Hardt W, Chen L, Schuebel KE, Bustelo XR, Galán JE. S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells Cell. 93: 815-826. PMID 9630225 DOI: 10.1016/S0092-8674(00)81442-7  0.478
1998 Kubori T, Matsushima Y, Nakamura D, Uralil J, Lara-Tejero M, Sukhan A, Galán JE, Aizawa SI. Supramolecular structure of the Salmonella typhimurium type III protein secretion system. Science (New York, N.Y.). 280: 602-5. PMID 9554854 DOI: 10.1126/Science.280.5363.602  0.759
1998 Palmer LE, Hobble S, Galán JE, Bliska JB. YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-α production and downregulation of the MAP kinases p38 and JNK Molecular Microbiology. 27: 953-965. PMID 9535085 DOI: 10.1046/J.1365-2958.1998.00740.X  0.31
1998 Fu Y, Galán JE. The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton Molecular Microbiology. 27: 359-368. PMID 9484891 DOI: 10.1046/J.1365-2958.1998.00684.X  0.49
1998 Hardt W, Urlaub H, Galán JE. A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage. Proceedings of the National Academy of Sciences of the United States of America. 95: 2574-2579. PMID 9482928 DOI: 10.1073/Pnas.95.5.2574  0.534
1998 Galán JE. 'Avirulence genes' in animal pathogens? Trends in Microbiology. 6: 3-6. PMID 9481815 DOI: 10.1016/S0966-842X(97)01183-9  0.35
1997 Hardt W, Galán JE. A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria Proceedings of the National Academy of Sciences of the United States of America. 94: 9887-9892. PMID 9275221 DOI: 10.1073/Pnas.94.18.9887  0.522
1997 Collazo CM, Galán JE. The invasion-associated type-III protein secretion system in Salmonella--a review. Gene. 192: 51-59. PMID 9224874 DOI: 10.1016/S0378-1119(96)00825-6  0.522
1997 Collazo CM, Galán JE. The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell. Molecular Microbiology. 24: 747-756. PMID 9194702 DOI: 10.1046/J.1365-2958.1997.3781740.X  0.52
1997 Ginocchio CC, Rahn K, Clarke RC, Galán JE. Naturally occurring deletions in the centisome 63 pathogenicity island of environmental isolates of Salmonella spp. Infection and Immunity. 65: 1267-1272. PMID 9119461 DOI: 10.1128/Iai.65.4.1267-1272.1997  0.364
1996 Galán JE, Bliska JB. Cross-talk between bacterial pathogens and their host cells Annual Review of Cell and Developmental Biology. 12: 221-255. PMID 8970727 DOI: 10.1146/Annurev.Cellbio.12.1.221  0.521
1996 Chen LM, Hobbie S, Galán JE. Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses Science. 274: 2115-2118. PMID 8953049 DOI: 10.1126/Science.274.5295.2115  0.495
1996 Chen LM, Kaniga K, Galán JE. Salmonella spp. are cytotoxic for cultured macrophages Molecular Microbiology. 21: 1101-1115. PMID 8885278 DOI: 10.1046/J.1365-2958.1996.471410.X  0.507
1996 Kaniga K, Uralil J, Bliska JB, Galán JE. A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium Molecular Microbiology. 21: 633-641. PMID 8866485 DOI: 10.1111/J.1365-2958.1996.Tb02571.X  0.506
1996 Collazo CM, Galán JE. Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium. Infection and Immunity. 64: 3524-3531. PMID 8751894 DOI: 10.1128/Iai.64.9.3524-3531.1996  0.478
1996 Galán JE. Molecular and cellular bases of Salmonella entry into host cells. Current Topics in Microbiology and Immunology. 209: 43-60. PMID 8742245 DOI: 10.1007/978-3-642-85216-9_3  0.321
1996 Galán JE. Molecular genetic bases of Salmonella entry into host cells Molecular Microbiology. 20: 263-271. PMID 8733226 DOI: 10.1111/J.1365-2958.1996.Tb02615.X  0.503
1995 Kaniga K, Trollinger D, Galan JE. Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins Journal of Bacteriology. 177: 7078-7085. PMID 8522512 DOI: 10.1128/Jb.177.24.7078-7085.1995  0.477
1995 Ginocchio CC, Galan JE. Functional conservation among members of the Salmonella typhimurium InvA family of proteins Infection and Immunity. 63: 729-732. PMID 7822051  0.326
1995 Kaniga K, Tucker S, Trollinger D, Galan JE. Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells Journal of Bacteriology. 177: 3965-3971. PMID 7608068 DOI: 10.1128/Jb.177.14.3965-3971.1995  0.508
1995 Zierler MK, Galan JE. Contact with cultured epithelial cells stimulates secretion of Salmonella typhimurium invasion protein InvJ Infection and Immunity. 63: 4024-4028. PMID 7558314  0.364
1994 Galán JE. Salmonella entry into mammalian cells: different yet converging signal transduction pathways? Trends in Cell Biology. 4: 196-199. PMID 14731677 DOI: 10.1016/0962-8924(94)90136-8  0.37
1994 Ginocchio CC, Olmsted SB, Wells CL, Galán JE. Contact with epithelial cells induces the formation of surface appendages on Salmonella typhimurium Cell. 76: 717-724. PMID 8124710 DOI: 10.1016/0092-8674(94)90510-X  0.462
1994 Eichelberg K, Ginocchio CC, Galan JE. Molecular and functional characterization of the Salmonella typhimurium invasion genes invB and invC: Homology of InvC to the F0F1 ATPase family of proteins Journal of Bacteriology. 176: 4501-4510. PMID 8045880 DOI: 10.1128/Jb.176.15.4501-4510.1994  0.439
1994 Kaniga K, Bossio JC, Galán JE. The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins Molecular Microbiology. 13: 555-568. PMID 7997169 DOI: 10.1111/J.1365-2958.1994.Tb00450.X  0.376
1994 Pace JL, Galan JE. Measurement of free intracellular calcium levels in epithelial cells as consequence of bacterial invasion Methods in Enzymology. 236: 482-490. PMID 7968633 DOI: 10.1016/0076-6879(94)36037-5  0.331
1994 Galan JE. Interactions of bacteria with non-phagocytic cells Current Opinion in Immunology. 6: 590-595. PMID 7946047 DOI: 10.1016/0952-7915(94)90146-5  0.456
1993 Bliska JB, Galán JE, Falkow S. Signal transduction in the mammalian cell during bacterial attachment and entry. Cell. 73: 903-20. PMID 8500180 DOI: 10.1016/0092-8674(93)90270-Z  0.376
1993 Pace J, Hayman MJ, Galán JE. Signal transduction and invasion of epithelial cells by S. typhimurium Cell. 72: 505-514. PMID 8382566 DOI: 10.1016/0092-8674(93)90070-7  0.428
1993 Altmeyer RM, McNern JK, Bossio JC, Rosenshine I, Finlay BB, Galán JE. Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells. Molecular Microbiology. 7: 89-98. PMID 8382333 DOI: 10.1111/J.1365-2958.1993.Tb01100.X  0.375
1992 Ginocchio C, Pace J, Galan JE. Identification and molecular characterization of a Salmonella typhimurium gene involved in triggering the internalization of salmonellae into cultured epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 89: 5976-5980. PMID 1631083 DOI: 10.1073/Pnas.89.13.5976  0.448
1992 Galan JE, Ginocchio C, Costeas P. Molecular and functional characterization of the Salmonella invasion gene invA: Homology of InvA to members of a new protein family Journal of Bacteriology. 174: 4338-4349. PMID 1624429 DOI: 10.1128/Jb.174.13.4338-4349.1992  0.493
1992 Galán JE, Pace J, Hayman MJ. Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium Nature. 357: 588-589. PMID 1608468 DOI: 10.1038/357588A0  0.413
1992 Rahn K, De Grandis SA, Clarke RC, McEwen SA, Galán JE, Ginocchio C, Curtiss R, Gyles CL. Amplification of an invA gene sequence of Salmonella typhimurium by polymerase chain reaction as a specific method of detection of Salmonella Molecular and Cellular Probes. 6: 271-279. PMID 1528198 DOI: 10.1016/0890-8508(92)90002-F  0.315
1991 Galan JE, Curtiss R. Distribution of the invA, -B, -C, and -D genes of Salmonella typhimurium among other Salmonella serovars: invA mutants of Salmonella typhi are deficient for entry into mammalian cells Infection and Immunity. 59: 2901-2908. PMID 1879916 DOI: 10.1128/Iai.59.9.2901-2908.1991  0.388
1990 Galán JE, Nakayama K, Curtiss R. Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains. Gene. 94: 29-35. PMID 2227450 DOI: 10.1016/0378-1119(90)90464-3  0.324
1990 Galan JE, Curtiss R. Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling Infection and Immunity. 58: 1879-1885. PMID 2160435 DOI: 10.1128/Iai.58.6.1879-1885.1990  0.339
1989 Galán JE, Curtiss R. Virulence and vaccine potential of phoP mutants of Salmonella typhimurium Microbial Pathogenesis. 6: 433-443. PMID 2671582 DOI: 10.1016/0882-4010(89)90085-5  0.376
1989 Galan JE, Curtiss R. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells Proceedings of the National Academy of Sciences of the United States of America. 86: 6383-6387. PMID 2548211 DOI: 10.1073/Pnas.86.16.6383  0.38
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