Christian Schindler - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Immunology, Microbiology Biology
Website:
https://microbiology.columbia.edu/faculty-christian-schindler

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ojcius DM, Jafari A, Yeruva L, Schindler CW, Abdul-Sater AA. Dicer regulates activation of the NLRP3 inflammasome. Plos One. 14: e0215689. PMID 31013297 DOI: 10.1371/Journal.Pone.0215689  0.682
2016 Majoros A, Platanitis E, Szappanos D, Cheon H, Vogl C, Shukla P, Stark GR, Sexl V, Schreiber R, Schindler C, Müller M, Decker T. Response to interferons and antibacterial innate immunity in the absence of tyrosine-phosphorylated STAT1. Embo Reports. PMID 26882544 DOI: 10.15252/Embr.201540726  0.372
2015 Abdul-Sater AA, Majoros A, Plumlee CR, Perry S, Gu AD, Lee C, Shresta S, Decker T, Schindler C. Different STAT Transcription Complexes Drive Early and Delayed Responses to Type I IFNs. Journal of Immunology (Baltimore, Md. : 1950). 195: 210-6. PMID 26019270 DOI: 10.4049/Jimmunol.1401139  0.79
2015 Rizzuti D, Ang M, Sokollik C, Wu T, Abdullah M, Greenfield L, Fattouh R, Reardon C, Tang M, Diao J, Schindler C, Cattral M, Jones NL. Helicobacter pylori inhibits dendritic cell maturation via interleukin-10-mediated activation of the signal transducer and activator of transcription 3 pathway. Journal of Innate Immunity. 7: 199-211. PMID 25412627 DOI: 10.1159/000368232  0.301
2013 Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. Embo Reports. 14: 900-6. PMID 24008845 DOI: 10.1038/Embor.2013.132  0.708
2013 Rizzuti D, Wu T, Fattouh R, Reardon C, Ang M, Haight J, Schindler C, Jones NL. Tu1713 Helicobacter pylori Activates Signal Transducer and Activator of Transcription 3 to Blunt Dendritic Cell Maturation Gastroenterology. 144: S-828. DOI: 10.1016/S0016-5085(13)63077-2  0.319
2012 Abdul-Sater AA, Grajkowski A, Erdjument-Bromage H, Plumlee C, Levi A, Schreiber MT, Lee C, Shuman H, Beaucage SL, Schindler C. The overlapping host responses to bacterial cyclic dinucleotides. Microbes and Infection / Institut Pasteur. 14: 188-97. PMID 21933720 DOI: 10.1016/J.Micinf.2011.09.002  0.769
2011 Schindler C, Shuai K, Prezioso VR, Darnell JE. Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science. 1992. 257: 809-813. Journal of Immunology (Baltimore, Md. : 1950). 187: 5489-94. PMID 22102732  0.689
2011 Parker D, Martin FJ, Soong G, Harfenist BS, Aguilar JL, Ratner AJ, Fitzgerald KA, Schindler C, Prince A. Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract. Mbio. 2: e00016-11. PMID 21586648 DOI: 10.1128/Mbio.00016-11  0.333
2011 Perry ST, Buck MD, Lada SM, Schindler C, Shresta S. STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor. Plos Pathogens. 7: e1001297. PMID 21379341 DOI: 10.1371/Journal.Ppat.1001297  0.351
2010 Ashour J, Morrison J, Laurent-Rolle M, Belicha-Villanueva A, Plumlee CR, Bernal-Rubio D, Williams KL, Harris E, Fernandez-Sesma A, Schindler C, García-Sastre A. Mouse STAT2 restricts early dengue virus replication. Cell Host & Microbe. 8: 410-21. PMID 21075352 DOI: 10.1016/J.Chom.2010.10.007  0.686
2010 Jewell NA, Cline T, Mertz SE, Smirnov SV, Flaño E, Schindler C, Grieves JL, Durbin RK, Kotenko SV, Durbin JE. Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo. Journal of Virology. 84: 11515-22. PMID 20739515 DOI: 10.1128/Jvi.01703-09  0.309
2010 Farlik M, Reutterer B, Schindler C, Greten F, Vogl C, Müller M, Decker T. Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression. Immunity. 33: 25-34. PMID 20637660 DOI: 10.1016/J.Immuni.2010.07.001  0.318
2010 Melillo JA, Song L, Bhagat G, Blazquez AB, Plumlee CR, Lee C, Berin C, Reizis B, Schindler C. Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function. Journal of Immunology (Baltimore, Md. : 1950). 184: 2638-45. PMID 20124100 DOI: 10.4049/Jimmunol.0902960  0.762
2009 Plumlee CR, Lee C, Beg AA, Decker T, Shuman HA, Schindler C. Interferons direct an effective innate response to Legionella pneumophila infection. The Journal of Biological Chemistry. 284: 30058-66. PMID 19720834 DOI: 10.1074/Jbc.M109.018283  0.693
2009 Martin FJ, Gomez MI, Wetzel DM, Memmi G, O'Seaghdha M, Soong G, Schindler C, Prince A. Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A. The Journal of Clinical Investigation. 119: 1931-9. PMID 19603548 DOI: 10.1172/Jci35879  0.351
2009 Ashour J, Laurent-Rolle M, Plumlee CR, Bernal D, Fernandez-Sesma A, Schindler C, García-Sastre A. Mouse STAT2 is a dengue virus host restriction factor Cytokine. 48: 62-63. DOI: 10.1016/J.Cyto.2009.07.198  0.658
2008 Schindler C, Plumlee C. Inteferons pen the JAK-STAT pathway. Seminars in Cell & Developmental Biology. 19: 311-8. PMID 18765289 DOI: 10.1016/J.Semcdb.2008.08.010  0.716
2008 Zhao W, Lee C, Piganis R, Plumlee C, de Weerd N, Hertzog PJ, Schindler C. A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs. Journal of Immunology (Baltimore, Md. : 1950). 180: 5483-9. PMID 18390731 DOI: 10.4049/Jimmunol.180.8.5483  0.708
2008 Song L, Plumlee C, Lee C, Seeley J, Bhagat G, Blazquez AB, Berin C, Reizis B, Schindler C. SY-21 Cytokine signals regulate the interface of innate and adaptive immunity Cytokine. 43: 304. DOI: 10.1016/J.Cyto.2008.07.473  0.675
2008 Plumlee CR, Schindler C. 256 The role of Type I interferon in legionella infection of murine and human macrophages Cytokine. 43: 300. DOI: 10.1016/J.Cyto.2008.07.321  0.656
2008 de Weerd NA, Piganis R, Zaker-Tabrizi L, Reid H, Fenner J, Noppert S, Gould J, Scott B, Rossjohn J, Zhao W, Lee C, Plumlee C, Schindler C, Hertzog PJ. 221 Structure-function characterization of type I interferon receptor signaling regulation Cytokine. 43: 292. DOI: 10.1016/J.Cyto.2008.07.285  0.672
2007 Zhao W, Cha EN, Lee C, Park CY, Schindler C. Stat2-dependent regulation of MHC class II expression. Journal of Immunology (Baltimore, Md. : 1950). 179: 463-71. PMID 17579067 DOI: 10.4049/Jimmunol.179.1.463  0.741
2006 Schindler C. Teaching resources. Cytokine receptors and Jak-STAT signaling. Science's Stke : Signal Transduction Knowledge Environment. 2006: tr7. PMID 16757735 DOI: 10.1126/Stke.3382006Tr7  0.314
2006 Schindler C, Melillo J. Signaling Through JAKs and STATs: Interferons Lead the Way Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200500070  0.786
2005 Gimeno R, Lee CK, Schindler C, Levy DE. Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes Molecular and Cellular Biology. 25: 5456-5465. PMID 15964802 DOI: 10.1128/Mcb.25.13.5456-5465.2005  0.341
2003 Wang J, Pham-Mitchell N, Schindler C, Campbell IL. Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain. The Journal of Clinical Investigation. 112: 535-43. PMID 12925694 DOI: 10.1172/Jci18637  0.352
2003 Braunstein J, Brutsaert S, Olson R, Schindler C. STATs dimerize in the absence of phosphorylation. The Journal of Biological Chemistry. 278: 34133-40. PMID 12832402 DOI: 10.1074/Jbc.M304531200  0.777
2003 Bhattacharya S, Schindler C. Regulation of Stat3 nuclear export. The Journal of Clinical Investigation. 111: 553-9. PMID 12588893 DOI: 10.1172/Jci15372  0.361
2000 Park C, Li S, Cha E, Schindler C. Immune response in Stat2 knockout mice Immunity. 13: 795-804. PMID 11163195 DOI: 10.1016/S1074-7613(00)00077-7  0.753
2000 Collum RG, Brutsaert S, Lee G, Schindler C. A Stat3-interacting protein (StIP1) regulates cytokine signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 97: 10120-5. PMID 10954736 DOI: 10.1073/Pnas.170192197  0.784
2000 Piazza F, Valens J, Lagasse E, Schindler C. Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing Blood. 96: 1358-1365. DOI: 10.1182/Blood.V96.4.1358  0.341
1999 Schindler C, Strehlow I. Cytokines and STAT signaling. Advances in Pharmacology. 47: 113-174. PMID 10582086 DOI: 10.1016/S1054-3589(08)60111-8  0.374
1999 Schindler C. Cytokines and JAK-STAT signaling. Experimental Cell Research. 253: 7-14. PMID 10579906 DOI: 10.1006/Excr.1999.4670  0.353
1999 Schindler C, Brutsaert S. Interferons as a paradigm for cytokine signal transduction. Cellular and Molecular Life Sciences : Cmls. 55: 1509-22. PMID 10526569 DOI: 10.1007/S000180050391  0.779
1999 Park C, Lecomte M, Schindler C. Murine Stat2 is uncharacteristically divergent Nucleic Acids Research. 27: 4191-4199. PMID 10518610 DOI: 10.1093/Nar/27.21.4191  0.612
1999 Lee C, Piazza F, Brutsaert S, Valens J, Strehlow I, Jarosinski M, Saris C, Schindler C. Characterization of the Stat5 protease. The Journal of Biological Chemistry. 274: 26767-75. PMID 10480881 DOI: 10.1074/Jbc.274.38.26767  0.776
1998 Strehlow I, Schindler C. Amino-Terminal Signal Transducer And Activator Of Transcription (Stat) Domains Regulate Nuclear Translocation And Stat Deactivation Journal of Biological Chemistry. 273: 28049-28056. PMID 9774421 DOI: 10.1074/Jbc.273.43.28049  0.358
1998 Park C, Schindler C. Protein-DNA interactions in interferon-gamma signaling. Methods. 15: 175-188. PMID 9735303 DOI: 10.1006/Meth.1998.0622  0.597
1998 schindler C. STATs as activators of apoptosis Trends in Cell Biology. 8: 97-98. PMID 9695817 DOI: 10.1016/S0962-8924(98)01233-1  0.342
1997 Azam M, Lee C, Strehlow I, Schindler C. Functionally Distinct Isoforms of STAT5 Are Generated by Protein Processing Immunity. 6: 691-701. PMID 9208842 DOI: 10.1016/S1074-7613(00)80445-8  0.369
1996 Gupta S, Yan H, Wong LH, Ralph S, Krolewski J, Schindler C. The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals. The Embo Journal. 15: 1075-1084. DOI: 10.1002/J.1460-2075.1996.Tb00445.X  0.344
1995 Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell JE, Mui AL, Miyajima A, Quelle FW, Ihle JN. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics. 29: 225-8. PMID 8530075 DOI: 10.1006/Geno.1995.1235  0.451
1995 Streuli CH, Edwards GM, Delcommenne M, Whitelaw CBA, Burdon TG, Schindler C, Watson CJ. Stat5 as a Target for Regulation by Extracellular Matrix Journal of Biological Chemistry. 270: 21639-21644. PMID 7665578 DOI: 10.1074/Jbc.270.37.21639  0.318
1995 Schindler C, Darnell JE. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annual Review of Biochemistry. 64: 621-51. PMID 7574495 DOI: 10.1146/annurev.bi.64.070195.003201  0.498
1995 Azam M, Erdjument-Bromage H, Kreider BL, Xia M, Quelle F, Basu R, Saris C, Tempst P, Ihle JN, Schindler C. Interleukin‐3 signals through multiple isoforms of Stat5. The Embo Journal. 14: 1402-1411. DOI: 10.1002/J.1460-2075.1995.Tb07126.X  0.332
1994 Improta T, Schindler C, Horvath CM, Kerr IM, Stark GR, Darnell JE. Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 4776-80. PMID 8197134 DOI: 10.1073/Pnas.91.11.4776  0.462
1993 Silvennoinen O, Schindler C, Schlessinger J, Levy DE. Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation. Science (New York, N.Y.). 261: 1736-9. PMID 8378775 DOI: 10.1126/Science.8378775  0.301
1993 Kanno Y, Kozak CA, Schindler C, Driggers PH, Ennist DL, Gleason SL, Darnell JE, Ozato K. The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds. Molecular and Cellular Biology. 13: 3951-63. PMID 8321202 DOI: 10.1128/Mcb.13.7.3951  0.467
1993 Müller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell JE, Stark GR, Kerr IM. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. The Embo Journal. 12: 4221-8. PMID 7693454 DOI: 10.1002/j.1460-2075.1993.tb06106.x  0.453
1992 Veals SA, Schindler C, Leonard D, Fu XY, Aebersold R, Darnell JE, Levy DE. Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Molecular and Cellular Biology. 12: 3315-24. PMID 1630447  0.461
1992 Fu XY, Schindler C, Improta T, Aebersold R, Darnell JE. The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 89: 7840-3. PMID 1502204  0.46
1992 Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE. Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proceedings of the National Academy of Sciences of the United States of America. 89: 7836-9. PMID 1502203  0.43
1992 Schindler C, Shuai K, Prezioso VR, Darnell JE. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (New York, N.Y.). 257: 809-13. PMID 1496401 DOI: 10.1126/Science.1496401  0.707
1992 Shuai K, Schindler C, Prezioso VR, Darnell JE. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science (New York, N.Y.). 258: 1808-12. PMID 1281555 DOI: 10.1126/Science.1281555  0.715
1985 Schindler CW, Rush MG. Discrete size classes of monkey extrachromosomal circular DNA containing the L1 family of long interspersed nucleotide sequences are produced by a general non-sequence specific mechanism. Nucleic Acids Research. 13: 8247-58. PMID 2999716 DOI: 10.1093/Nar/13.22.8247  0.586
1985 Schindler CW, Rush MG. The KpnI family of long interspersed nucleotide sequences is present on discrete sizes of circular DNA in monkey (BSC-1) cells. Journal of Molecular Biology. 181: 161-73. PMID 2984431 DOI: 10.1016/0022-2836(85)90082-8  0.583
1985 Paulson KE, Deka N, Schmid CW, Misra R, Schindler CW, Rush MG, Kadyk L, Leinwand L. A transposon-like element in human DNA. Nature. 316: 359-61. PMID 2862587 DOI: 10.1038/316359A0  0.581
1984 Krolewski JJ, Schindler CW, Rush MG. Structure of extrachromosomal circular DNAs containing both the Alu family of dispersed repetitive sequences and other regions of chromosomal DNA. Journal of Molecular Biology. 174: 41-54. PMID 6325708 DOI: 10.1016/0022-2836(84)90364-4  0.571
1982 Schindler CW, Krolewski JJ, Rush MG. Selective trapping of circular double-stranded DNA molecules in solidifying agarose. Plasmid. 7: 263-70. PMID 6285399 DOI: 10.1016/0147-619X(82)90007-5  0.57
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