F Markus Leweke, MD, MA - Publications

Affiliations: 
1999-2009 Psychiatry and Psychotherapy University of Cologne, Köln, Nordrhein-Westfalen, Germany 
 2009- Central Institute of Mental Health Ruprecht-Karls-University Heidelberg, Heidelberg, Baden-Württemberg, Germany 

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kroll SL, Hulka LM, Kexel AK, Vonmoos M, Preller KH, Treyer V, Ametamey SM, Baumgartner MR, Boost C, Pahlisch F, Rohleder C, Leweke FM, Quednow BB. Plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density. Translational Psychiatry. 13: 325. PMID 37857616 DOI: 10.1038/s41398-023-02628-7  0.62
2023 Hickie IB, Iorfino F, Rohleder C, Song YJC, Nichles A, Zmicerevska N, Capon W, Guastella AJ, Leweke FM, Scott J, McGorry P, Mihalopoulos C, Killackey E, Chong MK, McKenna S, et al. EMPOWERED trial: protocol for a randomised control trial of digitally supported, highly personalised and measurement-based care to improve functional outcomes in young people with mood disorders. Bmj Open. 13: e072082. PMID 37821139 DOI: 10.1136/bmjopen-2023-072082  0.739
2023 Koethe D, Rohleder C, Kracht L, Leweke FM. Cannabidiol enhances cerebral glucose utilization and ameliorates psychopathology and cognition: A case report in a clinically high-risk mental state. Frontiers in Psychiatry. 14: 1088459. PMID 36937734 DOI: 10.3389/fpsyt.2023.1088459  0.768
2022 Carpenter JS, Zmicerevska N, Crouse JJ, Nichles A, Garland A, Song YJC, Wilson C, Rohleder C, McHugh C, Leweke FM, Koethe D, Scott EM, Hickie IB. Effects of adjunctive brexpiprazole on sleep-wake and circadian parameters in youth with depressive disorders: study protocol for a clinical trial. Bmj Open. 12: e056298. PMID 36691133 DOI: 10.1136/bmjopen-2021-056298  0.745
2022 Heres S, Cordes J, Feyerabend S, Schmidt-Kraepelin C, Musil R, Riedel M, Spellmann I, Langguth B, Landgrebe M, Fran E, Petcu C C, Hahn E, Ta TMT, Matei V, Dehelean L, ... ... Leweke FM, et al. Changing the Antipsychotic in Early Nonimprovers to Amisulpride or Olanzapine: Randomized, Double-Blind Trial in Patients With Schizophrenia. Schizophrenia Bulletin. PMID 35857811 DOI: 10.1093/schbul/sbac068  0.381
2022 Couttas TA, Jieu B, Rohleder C, Leweke FM. Current State of Fluid Lipid Biomarkers for Personalized Diagnostics and Therapeutics in Schizophrenia Spectrum Disorders and Related Psychoses: A Narrative Review. Frontiers in Psychiatry. 13: 885904. PMID 35711577 DOI: 10.3389/fpsyt.2022.885904  0.701
2022 Couttas TA, Boost C, Pahlisch F, Sykorova EB, Leweke JE, Koethe D, Endepols H, Rohleder C, Leweke FM. Simultaneous Assessment of Serum Levels and Pharmacologic Effects of Cannabinoids on Endocannabinoids and -Acylethanolamines by Liquid Chromatography-Tandem Mass Spectrometry. Cannabis and Cannabinoid Research. PMID 35580134 DOI: 10.1089/can.2021.0181  0.731
2022 Banati RB, Rohleder C, Leweke FM, Mueller N, Sawa A, Yolken RH, Hickie IB. Editorial: Immune Associated Mental Illnesses in Adolescents and Young Adults: Pathophysiological Role and Therapeutic Perspectives. Frontiers in Psychiatry. 13: 871719. PMID 35360122 DOI: 10.3389/fpsyt.2022.871719  0.621
2021 Xiao MF, Roh SE, Zhou J, Chien CC, Lucey BP, Craig MT, Hayes LN, Coughlin JM, Leweke FM, Jia M, Xu D, Zhou W, Conover Talbot C, Arnold DB, Staley M, et al. A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function. Science Advances. 7: eabf6935. PMID 34818031 DOI: 10.1126/sciadv.abf6935  0.329
2021 Nichles A, Zmicerevska N, Song YJC, Wilson C, McHugh C, Hamilton B, Crouse J, Rohleder C, Carpenter JS, Ho N, Hermens DF, Wray N, Scott J, Merikangas KR, Leweke FM, et al. Neurobiology Youth Follow-up Study: protocol to establish a longitudinal and prospective research database using multimodal assessments for current and past mental health treatment-seeking young people within an early intervention service. Bmj Open. 11: e044731. PMID 34145010 DOI: 10.1136/bmjopen-2020-044731  0.752
2021 Moldavski A, Wenz H, Lange BE, Rohleder C, Leweke FM. Case Report: Severe Adolescent Major Depressive Syndrome Turns Out to Be an Unusual Case of Anti-NMDA Receptor Encephalitis. Frontiers in Psychiatry. 12: 679996. PMID 34113272 DOI: 10.3389/fpsyt.2021.679996  0.669
2021 Leweke FM, Rohleder C, Gerth CW, Hellmich M, Pukrop R, Koethe D. Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial. Frontiers in Pharmacology. 12: 614811. PMID 33995015 DOI: 10.3389/fphar.2021.614811  0.787
2021 Bien CG, Rohleder C, Mueller JK, Bien CI, Koethe D, Leweke FM. Neural Autoantibodies in Cerebrospinal Fluid and Serum in Clinical High Risk for Psychosis, First-Episode Psychosis, and Healthy Volunteers. Frontiers in Psychiatry. 12: 654602. PMID 33841216 DOI: 10.3389/fpsyt.2021.654602  0.784
2020 Woelfl T, Rohleder C, Mueller JK, Lange B, Reuter A, Schmidt AM, Koethe D, Hellmich M, Leweke FM. Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy Volunteers. Frontiers in Psychiatry. 11: 576877. PMID 33304282 DOI: 10.3389/fpsyt.2020.576877  0.769
2020 Rohleder C, Song YJC, Crouse JJ, Davenport TA, Iorfino F, Hamilton B, Zmicerevska N, Nichles A, Carpenter JS, Tickell AM, Wilson C, Cross SP, Guastella AJ, Koethe D, Leweke FM, et al. Youth Mental Health Tracker: protocol to establish a longitudinal cohort and research database for young people attending Australian mental health services. Bmj Open. 10: e035379. PMID 32513883 DOI: 10.1136/Bmjopen-2019-035379  0.749
2020 Bouter Y, Brzózka MM, Rygula R, Pahlisch F, Leweke FM, Havemann-Reinecke U, Rohleder C. Chronic Psychosocial Stress Causes Increased Anxiety-Like Behavior and Alters Endocannabinoid Levels in the Brain of C57Bl/6J Mice. Cannabis and Cannabinoid Research. 5: 51-61. PMID 32322676 DOI: 10.1089/can.2019.0041  0.622
2020 Schoevers J, Leweke JE, Leweke FM. Cannabidiol as a treatment option for schizophrenia: recent evidence and current studies. Current Opinion in Psychiatry. 33: 185-191. PMID 32073423 DOI: 10.1097/Yco.0000000000000596  0.495
2019 Chadwick VL, Rohleder C, Koethe D, Leweke FM. Cannabinoids and the endocannabinoid system in anxiety, depression, and dysregulation of emotion in humans. Current Opinion in Psychiatry. PMID 31714262 DOI: 10.1097/Yco.0000000000000562  0.74
2019 Hasan A, von Keller R, Friemel CM, Hall W, Schneider M, Koethe D, Leweke FM, Strube W, Hoch E. Cannabis use and psychosis: a review of reviews. European Archives of Psychiatry and Clinical Neuroscience. PMID 31563981 DOI: 10.1007/S00406-019-01068-Z  0.634
2019 Hirjak D, Gass P, Deuschle M, Leweke FM, Böhringer A, Schenkel N, Borgwedel D, Heser M, Breisacher A, Meyer-Lindenberg A. [The CIMH track concept in the treatment of psychotic disorders]. Der Nervenarzt. PMID 30976829 DOI: 10.1007/S00115-019-0711-9  0.494
2019 Rohleder C, Pahlisch F, Graf R, Endepols H, Leweke FM. Different pharmaceutical preparations of Δ -tetrahydrocannabinol differentially affect its behavioral effects in rats. Addiction Biology. PMID 30938471 DOI: 10.1111/Adb.12745  0.692
2019 Leweke FM, Hirjak D, Staudter C, Borgwedel D, Coenen-Daniel M, Heser M, Erk K, Juckel G, Beivers A, Meyer-Lindenberg A. [The CIMH Track Concept in Psychiatry: Syndrome-specific Treatment across Modalities - Part 1 - Theoretical background]. Fortschritte Der Neurologie-Psychiatrie. PMID 30763961 DOI: 10.1055/A-0759-1859  0.464
2019 Cooper JD, Han SYS, Tomasik J, Ozcan S, Rustogi N, van Beveren NJM, Leweke FM, Bahn S. Multimodel inference for biomarker development: an application to schizophrenia. Translational Psychiatry. 9: 83. PMID 30745560 DOI: 10.1038/S41398-019-0419-4  0.429
2019 Hirjak D, Leweke FM, Deuschle M, Staudter C, Borgwedel D, Coenen-Daniel M, Heser M, Erk K, Beivers A, Meyer-Lindenberg A. [The CIMH Track Concept in Psychiatry: Syndrome-specific Treatment across Modalities - Part 2 - Practical implementation]. Fortschritte Der Neurologie-Psychiatrie. PMID 30731483 DOI: 10.1055/A-0759-1957  0.461
2018 Grent-'t-Jong T, Gross J, Goense J, Wibral M, Gajwani R, Gumley AI, Lawrie SM, Schwannauer M, Schultze-Lutter F, Navarro Schröder T, Koethe D, Leweke FM, Singer W, Uhlhaas PJ. Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages. Elife. 7. PMID 30260771 DOI: 10.7554/Elife.37799  0.663
2018 Leweke FM, Mueller JK, Lange B, Fritze S, Topor CE, Koethe D, Rohleder C. Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia: Implications for Pharmacological Intervention. Cns Drugs. PMID 30022465 DOI: 10.1007/S40263-018-0539-Z  0.831
2018 Rohleder C, Koethe D, Fritze S, Topor CE, Leweke FM, Hirjak D. Neural correlates of binocular depth inversion illusion in antipsychotic-naïve first-episode schizophrenia patients. European Archives of Psychiatry and Clinical Neuroscience. PMID 29556734 DOI: 10.1007/S00406-018-0886-2  0.819
2018 Koethe D, Pahlisch F, Hellmich M, Rohleder C, Mueller JK, Meyer-Lindenberg A, Torrey EF, Piomelli D, Leweke FM. Familial Abnormalities of Endocannabinoid Signaling in Schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-26. PMID 29521179 DOI: 10.1080/15622975.2018.1449966  0.815
2018 Tomasik J, Smits SL, Leweke FM, Eljasz P, Pas S, Kahn RS, Osterhaus ADME, Bahn S, de Witte LD. Virus discovery analyses on post-mortem brain tissue and cerebrospinal fluid of schizophrenia patients. Schizophrenia Research. PMID 29478863 DOI: 10.1016/J.Schres.2018.02.012  0.399
2018 Grent-'t-Jong T, Gross J, Goense J, Wibral M, Gajwani R, Gumley AI, Lawrie SM, Schwannauer M, Schultze-Lutter F, Schröder TN, Koethe D, Leweke FM, Singer W, Uhlhaas PJ. Author response: Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages Elife. DOI: 10.7554/Elife.37799.017  0.392
2017 Cooper JD, Ozcan S, Gardner RM, Rustogi N, Wicks S, van Rees GF, Leweke FM, Dalman C, Karlsson H, Bahn S. Schizophrenia-risk and urban birth are associated with proteomic changes in neonatal dried blood spots. Translational Psychiatry. 7: 1290. PMID 29249827 DOI: 10.1038/S41398-017-0027-0  0.478
2017 Kannan G, Gressitt KL, Yang S, Stallings CR, Katsafanas E, Schweinfurth LA, Savage CLG, Adamos MB, Sweeney KM, Origoni AE, Khushalani S, Bahn S, Leweke FM, Dickerson FB, Yolken RH, et al. Pathogen-mediated NMDA receptor autoimmunity and cellular barrier dysfunction in schizophrenia. Translational Psychiatry. 7: e1186. PMID 28763062 DOI: 10.1038/Tp.2017.162  0.355
2017 Kranaster L, Hoyer C, Aksay SS, Bumb JM, Leweke FM, Janke C, Thiel M, Lutz B, Bindila L, Sartorius A. Electroconvulsive therapy enhances endocannabinoids in the cerebrospinal fluid of patients with major depression: a preliminary prospective study European Archives of Psychiatry and Clinical Neuroscience. 267: 781-786. PMID 28342110 DOI: 10.1007/S00406-017-0789-7  0.302
2017 Lange B, Mueller JK, Leweke FM, Bumb JM. How gender affects the pharmacotherapeutic approach to treating psychosis - A systematic review. Expert Opinion On Pharmacotherapy. PMID 28129701 DOI: 10.1080/14656566.2017.1288722  0.682
2017 Reuter AR, Mueller JK, Bumb JM, Rohleder C, Pahlisch F, Hanke F, Lange B, Koethe D, Schwarz E, Leweke FM. 570. Differential Association of Anandamide Levels with Binocular Depth Inversion Illusion Scores in Schizophrenia Biological Psychiatry. 81: S230-S231. DOI: 10.1016/J.Biopsych.2017.02.440  0.813
2016 Leucht S, Rossum IW, Heres S, Arango C, Fleischhacker WW, Glenthøj B, Leboyer M, Leweke FM, Lewis S, McGuire P, Meyer-Lindenberg A, Rujescu D, Kapur S, Kahn RS, Sommer IE. The Optimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) Trial: Rationale for Its Methodology and a Review of the Effectiveness of Switching Antipsychotics. Focus (American Psychiatric Publishing). 14: 378-386. PMID 31997959 DOI: 10.1176/appi.focus.140302  0.496
2016 Coughlin JM, Hayes LN, Tanaka T, Xiao M, Yolken RH, Worley P, Leweke FM, Sawa A. Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features. Schizophrenia Research. PMID 27889384 DOI: 10.1016/J.Schres.2016.10.040  0.426
2016 Rohleder C, Müller JK, Lange B, Leweke FM. Cannabidiol as a Potential New Type of an Antipsychotic. A Critical Review of the Evidence. Frontiers in Pharmacology. 7: 422. PMID 27877130 DOI: 10.3389/Fphar.2016.00422  0.727
2016 Mueller JK, Rohleder C, Leweke FM. What is the promise of nicotinergic compounds in schizophrenia treatment? Future Medicinal Chemistry. PMID 27739330 DOI: 10.4155/Fmc-2016-0154  0.813
2016 Reuter AR, Bumb JM, Mueller JK, Rohleder C, Pahlisch F, Hanke F, Arens E, Leweke FM, Koethe D, Schwarz E. Association of Anandamide with altered Binocular Depth Inversion Illusion in Schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-17. PMID 27734750 DOI: 10.1080/15622975.2016.1246750  0.827
2016 Rohleder C, Wiedermann D, Neumaier B, Drzezga A, Timmermann L, Graf R, Leweke FM, Endepols H. The Functional Networks of Prepulse Inhibition: Neuronal Connectivity Analysis Based on FDG-PET in Awake and Unrestrained Rats. Frontiers in Behavioral Neuroscience. 10: 148. PMID 27493627 DOI: 10.3389/Fnbeh.2016.00148  0.688
2016 Severance EG, Gressitt KL, Stallings CR, Katsafanas E, Schweinfurth LA, Savage CL, Adamos MB, Sweeney KM, Origoni AE, Khushalani S, Leweke FM, Dickerson FB, Yolken RH. Candida albicans exposures, sex specificity and cognitive deficits in schizophrenia and bipolar disorder. Npj Schizophrenia. 2: 16018. PMID 27336058 DOI: 10.1038/npjschz.2016.18  0.352
2016 Bumb JM, Enning F, Mueller JK, van der List T, Rohleder C, Findeisen P, Noelte I, Schwarz E, Leweke FM. Differential melatonin alterations in cerebrospinal fluid and serum of patients with major depressive disorder and bipolar disorder. Comprehensive Psychiatry. 68: 34-9. PMID 27234180 DOI: 10.1016/J.Comppsych.2016.03.005  0.77
2015 Leweke FM, Mueller JK, Lange B, Rohleder C. Therapeutic Potential of Cannabinoids in Psychosis. Biological Psychiatry. PMID 26852073 DOI: 10.1016/J.Biopsych.2015.11.018  0.827
2015 Tomasik J, Schwarz E, Lago SG, Rothermundt M, Leweke FM, van Beveren NJ, Guest PC, Rahmoune H, Steiner J, Bahn S. Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients. Brain, Behavior, and Immunity. PMID 26541453 DOI: 10.1016/J.Bbi.2015.10.019  0.402
2015 Chan MK, Krebs MO, Cox D, Guest PC, Yolken RH, Rahmoune H, Rothermundt M, Steiner J, Leweke FM, van Beveren NJ, Niebuhr DW, Weber NS, Cowan DN, Suarez-Pinilla P, Crespo-Facorro B, et al. Development of a blood-based molecular biomarker test for identification of schizophrenia before disease onset. Translational Psychiatry. 5: e601. PMID 26171982 DOI: 10.1038/Tp.2015.91  0.368
2015 Bumb JM, Enning F, Leweke FM. Drug repurposing and emerging adjunctive treatments for schizophrenia. Expert Opinion On Pharmacotherapy. 16: 1049-67. PMID 25866122 DOI: 10.1517/14656566.2015.1032248  0.476
2015 Jaros JA, Rahmoune H, Wesseling H, Leweke FM, Ozcan S, Guest PC, Bahn S. Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia. Proteomics. Clinical Applications. 9: 907-16. PMID 25821032 DOI: 10.1002/Prca.201400148  0.484
2015 Leucht S, Winter-van Rossum I, Heres S, Arango C, Fleischhacker WW, Glenthøj B, Leboyer M, Leweke FM, Lewis S, McGuire P, Meyer-Lindenberg A, Rujescu D, Kapur S, Kahn RS, Sommer IE. The optimization of treatment and management of schizophrenia in Europe (OPTiMiSE) trial: rationale for its methodology and a review of the effectiveness of switching antipsychotics. Schizophrenia Bulletin. 41: 549-58. PMID 25786408 DOI: 10.1093/Schbul/Sbv019  0.589
2015 Severance EG, Gressitt KL, Alaedini A, Rohleder C, Enning F, Bumb JM, Müller JK, Schwarz E, Yolken RH, Leweke FM. IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia. Brain, Behavior, and Immunity. 44: 148-58. PMID 25241021 DOI: 10.1016/J.Bbi.2014.09.009  0.748
2014 Grosshans M, Schwarz E, Bumb JM, Schaefer C, Rohleder C, Vollmert C, Vollstädt-Klein S, Tost H, Meyer-Lindenberg A, Kiefer F, Leweke FM. Oleoylethanolamide and human neural responses to food stimuli in obesity. Jama Psychiatry. 71: 1254-61. PMID 25229205 DOI: 10.1001/Jamapsychiatry.2014.1215  0.676
2014 Rohleder C, Jung F, Mertgens H, Wiedermann D, Sué M, Neumaier B, Graf R, Leweke FM, Endepols H. Neural correlates of sensorimotor gating: a metabolic positron emission tomography study in awake rats. Frontiers in Behavioral Neuroscience. 8: 178. PMID 24904330 DOI: 10.3389/Fnbeh.2014.00178  0.694
2014 van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, ... ... Leweke FM, et al. Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophrenia Bulletin. 40: 729-36. PMID 24860087 DOI: 10.1093/Schbul/Sbu069  0.728
2014 Rivolta D, Castellanos NP, Stawowsky C, Helbling S, Wibral M, Grützner C, Koethe D, Birkner K, Kranaster L, Enning F, Singer W, Leweke FM, Uhlhaas PJ. Source-reconstruction of event-related fields reveals hyperfunction and hypofunction of cortical circuits in antipsychotic-naive, first-episode schizophrenia patients during Mooney face processing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5909-17. PMID 24760850 DOI: 10.1523/Jneurosci.3752-13.2014  0.617
2014 Hayes LN, Severance EG, Leek JT, Gressitt KL, Rohleder C, Coughlin JM, Leweke FM, Yolken RH, Sawa A. Inflammatory molecular signature associated with infectious agents in psychosis. Schizophrenia Bulletin. 40: 963-72. PMID 24743863 DOI: 10.1093/Schbul/Sbu052  0.69
2014 Schaefer C, Enning F, Mueller JK, Bumb JM, Rohleder C, Odorfer TM, Klosterkötter J, Hellmich M, Koethe D, Schmahl C, Bohus M, Leweke FM. Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. European Archives of Psychiatry and Clinical Neuroscience. 264: 459-63. PMID 24253425 DOI: 10.1007/S00406-013-0470-8  0.763
2014 Schwarz E, van Beveren NJ, Ramsey J, Leweke FM, Rothermundt M, Bogerts B, Steiner J, Guest PC, Bahn S. Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways. Schizophrenia Bulletin. 40: 787-95. PMID 23934781 DOI: 10.1093/Schbul/Sbt105  0.483
2014 Bumb JM, Schwarz E, Enning F, Rohleder C, Findeisen P, Leweke FM, Noelte I. Sleep deprivation in humans: Effects on melatonin in cerebrospinal fluid and serum Sleep and Biological Rhythms. 12: 69-72. DOI: 10.1111/Sbr.12039  0.645
2014 Leweke FM, Hellmich M, Pahlisch F, Kranaster L, Koethe D. MODULATION OF THE ENDOCANNABINOID SYSTEM AS A POTENTIAL NEW TARGET IN THE TREATMENT OF SCHIZOPHRENIA Schizophrenia Research. 153: S47. DOI: 10.1016/S0920-9964(14)70153-7  0.7
2014 Leweke FM, Kranaster L, Hoyer C, Neatby M, Haensel A, Gross S, Nolden B, Klosterkötter J, Emrich H, Koethe D. THE BINOCULAR DEPTH INVERSION ILLUSION TEST – A BASIC MEASURE OF PERCEPTUAL INTEGRATION Schizophrenia Research. 153: S39. DOI: 10.1016/S0920-9964(14)70128-8  0.665
2013 Ramsey JM, Schwarz E, Guest PC, van Beveren NJ, Leweke FM, Rothermundt M, Bogerts B, Steiner J, Bahn S. Distinct molecular phenotypes in male and female schizophrenia patients. Plos One. 8: e78729. PMID 24244349 DOI: 10.1371/Journal.Pone.0078729  0.48
2013 Bumb JM, Enning F, Leweke FM. Repurposed drugs for the treatment of schizophrenia and bipolar disorders. Current Topics in Medicinal Chemistry. 13: 2364-85. PMID 24059460  0.338
2013 Severance EG, Gressitt KL, Stallings CR, Origoni AE, Khushalani S, Leweke FM, Dickerson FB, Yolken RH. Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia. Schizophrenia Research. 148: 130-7. PMID 23746484 DOI: 10.1016/J.Schres.2013.05.018  0.474
2013 Ceccarini J, De Hert M, Van Winkel R, Peuskens J, Bormans G, Kranaster L, Enning F, Koethe D, Leweke FM, Van Laere K. Increased ventral striatal CB1 receptor binding is related to negative symptoms in drug-free patients with schizophrenia. Neuroimage. 79: 304-12. PMID 23624489 DOI: 10.1016/J.Neuroimage.2013.04.052  0.66
2013 Morgan CJ, Page E, Schaefer C, Chatten K, Manocha A, Gulati S, Curran HV, Brandner B, Leweke FM. Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. The British Journal of Psychiatry : the Journal of Mental Science. 202: 381-2. PMID 23580381 DOI: 10.1192/Bjp.Bp.112.121178  0.331
2013 Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Molecular Psychiatry. 18: 10-1. PMID 22349781 DOI: 10.1038/Mp.2012.6  0.409
2013 Krishnamurthy D, Harris LW, Levin Y, Koutroukides TA, Rahmoune H, Pietsch S, Vanattou-Saifoudine N, Leweke FM, Guest PC, Bahn S. Metabolic, hormonal and stress-related molecular changes in post-mortem pituitary glands from schizophrenia subjects. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 14: 478-89. PMID 22248022 DOI: 10.3109/15622975.2011.601759  0.474
2012 Leweke FM, Odorfer TM, Bumb JM. Medical needs in the treatment of psychotic disorders. Handbook of Experimental Pharmacology. 165-85. PMID 23129332 DOI: 10.1007/978-3-642-25761-2_7  0.468
2012 Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, Klosterkötter J, Hellmich M, Koethe D. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational Psychiatry. 2: e94. PMID 22832859 DOI: 10.1038/Tp.2012.15  0.749
2012 Leweke FM. Anandamide dysfunction in prodromal and established psychosis. Current Pharmaceutical Design. 18: 5188-93. PMID 22716147 DOI: 10.2174/138161212802884843  0.511
2012 Jaros JA, Martins-de-Souza D, Rahmoune H, Rothermundt M, Leweke FM, Guest PC, Bahn S. Protein phosphorylation patterns in serum from schizophrenia patients and healthy controls. Journal of Proteomics. 76: 43-55. PMID 22641159 DOI: 10.1016/J.Jprot.2012.05.027  0.447
2012 Telford JE, Bones J, McManus C, Saldova R, Manning G, Doherty M, Leweke FM, Rothermundt M, Guest PC, Rahmoune H, Bahn S, Rudd PM. Antipsychotic treatment of acute paranoid schizophrenia patients with olanzapine results in altered glycosylation of serum glycoproteins. Journal of Proteome Research. 11: 3743-52. PMID 22594947 DOI: 10.1021/Pr300218H  0.472
2012 Severance EG, Alaedini A, Yang S, Halling M, Gressitt KL, Stallings CR, Origoni AE, Vaughan C, Khushalani S, Leweke FM, Dickerson FB, Yolken RH. Gastrointestinal inflammation and associated immune activation in schizophrenia. Schizophrenia Research. 138: 48-53. PMID 22446142 DOI: 10.1016/J.Schres.2012.02.025  0.462
2012 Jaros JA, Martins-de-Souza D, Rahmoune H, Schwarz E, Leweke FM, Guest PC, Bahn S. Differential phosphorylation of serum proteins reflecting inflammatory changes in schizophrenia patients. European Archives of Psychiatry and Clinical Neuroscience. 262: 453-5. PMID 22169887 DOI: 10.1007/S00406-011-0283-6  0.35
2012 Schwarz E, Guest PC, Rahmoune H, Harris LW, Wang L, Leweke FM, Rothermundt M, Bogerts B, Koethe D, Kranaster L, Ohrmann P, Suslow T, McAllister G, Spain M, Barnes A, et al. Identification of a biological signature for schizophrenia in serum. Molecular Psychiatry. 17: 494-502. PMID 21483431 DOI: 10.1038/Mp.2011.42  0.676
2012 Leweke FM, Koethe D, Pahlisch F, Hellmich M, Rohleder C, Meyer-Lindenberg A, Piomelli D. A TWIN STUDY ON ABNORMALITIES OF ENDOCANNABINOID FUNCTIONING IN SCHIZOPHRENIA AND BIPOLAR DISORDER Schizophrenia Research. 136: S26-S27. DOI: 10.1016/S0920-9964(12)70093-2  0.82
2011 Kranaster L, Koethe D, Hoyer C, Meyer-Lindenberg A, Leweke FM. Cerebrospinal fluid diagnostics in first-episode schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 261: 529-30. PMID 21298501 DOI: 10.1007/S00406-011-0193-7  0.745
2011 Guest PC, Schwarz E, Krishnamurthy D, Harris LW, Leweke FM, Rothermundt M, van Beveren NJ, Spain M, Barnes A, Steiner J, Rahmoune H, Bahn S. Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia. Psychoneuroendocrinology. 36: 1092-6. PMID 21251762 DOI: 10.1016/J.Psyneuen.2010.12.018  0.467
2011 Schwarz E, Whitfield P, Nahnsen S, Wang L, Major H, Leweke FM, Koethe D, Lio P, Bahn S. Alterations of primary fatty acid amides in serum of patients with severe mental illness. Frontiers in Bioscience (Elite Edition). 3: 308-14. PMID 21196311  0.709
2011 Leweke FM, Schneider M. Chronic pubertal cannabinoid treatment as a behavioural model for aspects of schizophrenia: effects of the atypical antipsychotic quetiapine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 43-51. PMID 20678304 DOI: 10.1017/S1461145710000842  0.379
2011 Herberth M, Koethe D, Cheng TM, Krzyszton ND, Schoeffmann S, Guest PC, Rahmoune H, Harris LW, Kranaster L, Leweke FM, Bahn S. Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patients. Molecular Psychiatry. 16: 848-59. PMID 20585325 DOI: 10.1038/Mp.2010.71  0.683
2010 Bray NJ, Leweke FM, Kapur S, Meyer-Lindenberg A. The neurobiology of schizophrenia: new leads and avenues for treatment. Current Opinion in Neurobiology. 20: 810-5. PMID 20934321 DOI: 10.1016/J.Conb.2010.09.008  0.613
2010 Stanta JL, Saldova R, Struwe WB, Byrne JC, Leweke FM, Rothermund M, Rahmoune H, Levin Y, Guest PC, Bahn S, Rudd PM. Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia. Journal of Proteome Research. 9: 4476-89. PMID 20578731 DOI: 10.1021/Pr1002356  0.485
2010 Schwarz E, Izmailov R, Spain M, Barnes A, Mapes JP, Guest PC, Rahmoune H, Pietsch S, Leweke FM, Rothermundt M, Steiner J, Koethe D, Kranaster L, Ohrmann P, Suslow T, et al. Validation of a blood-based laboratory test to aid in the confirmation of a diagnosis of schizophrenia. Biomarker Insights. 5: 39-47. PMID 20520744 DOI: 10.4137/Bmi.S4877  0.713
2010 Hoyer C, Kranaster L, Leweke FM, Klosterkötter J, Meyer-Lindenberg A, Koethe D. Familial differential treatment response in schizophrenia--lessons from a case of three affected siblings. Pharmacopsychiatry. 43: 196-7. PMID 20191444 DOI: 10.1055/s-0030-1248315  0.708
2010 Guest PC, Wang L, Harris LW, Burling K, Levin Y, Ernst A, Wayland MT, Umrania Y, Herberth M, Koethe D, van Beveren JM, Rothermundt M, McAllister G, Leweke FM, Steiner J, et al. Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naïve schizophrenia patients. Molecular Psychiatry. 15: 118-9. PMID 20098438 DOI: 10.1038/Mp.2009.81  0.661
2010 Levin Y, Wang L, Schwarz E, Koethe D, Leweke FM, Bahn S. Global proteomic profiling reveals altered proteomic signature in schizophrenia serum. Molecular Psychiatry. 15: 1088-100. PMID 19546861 DOI: 10.1038/Mp.2009.54  0.679
2010 Herberth M, Krzyszton DN, Koethe D, Craddock MR, Bulger E, Schwarz E, Guest P, Leweke FM, Bahn S. Differential effects on T-cell function following exposure to serum from schizophrenia smokers. Molecular Psychiatry. 15: 364-71. PMID 19002140 DOI: 10.1038/Mp.2008.120  0.64
2009 Leweke FM. Schizophrenia. Current Topics in Behavioral Neurosciences. 1: 387-96. PMID 21104393 DOI: 10.1007/978-3-540-88955-7_16  0.371
2009 Schwarz E, Leweke FM, Bahn S, Liò P. Clinical bioinformatics for complex disorders: a schizophrenia case study. Bmc Bioinformatics. 10: S6. PMID 19828082 DOI: 10.1186/1471-2105-10-S12-S6  0.386
2009 Koethe D, Hoyer C, Leweke FM. The endocannabinoid system as a target for modelling psychosis. Psychopharmacology. 206: 551-61. PMID 19529920 DOI: 10.1007/S00213-009-1591-7  0.706
2009 Koethe D, Giuffrida A, Schreiber D, Hellmich M, Schultze-Lutter F, Ruhrmann S, Klosterkötter J, Piomelli D, Leweke FM. Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. The British Journal of Psychiatry : the Journal of Mental Science. 194: 371-2. PMID 19336792 DOI: 10.1192/Bjp.Bp.108.053843  0.752
2009 Koethe D, Kranaster L, Hoyer C, Gross S, Neatby MA, Schultze-Lutter F, Ruhrmann S, Klosterkötter J, Hellmich M, Leweke FM. Binocular depth inversion as a paradigm of reduced visual information processing in prodromal state, antipsychotic-naïve and treated schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 259: 195-202. PMID 19165523 DOI: 10.1007/S00406-008-0851-6  0.732
2009 Koethe D, Schreiber D, Giuffrida A, Mauss C, Faulhaber J, Heydenreich B, Hellmich M, Graf R, Klosterkötter J, Piomelli D, Leweke FM. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 301-5. PMID 19137236 DOI: 10.1007/S00702-008-0169-6  0.662
2008 Schwarz E, Prabakaran S, Whitfield P, Major H, Leweke FM, Koethe D, McKenna P, Bahn S. High throughput lipidomic profiling of schizophrenia and bipolar disorder brain tissue reveals alterations of free fatty acids, phosphatidylcholines, and ceramides. Journal of Proteome Research. 7: 4266-77. PMID 18778095 DOI: 10.1021/Pr800188Y  0.68
2008 Koethe D, Bortolato M, Piomelli D, Leweke FM. Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. Pharmacopsychiatry. 41: 115-6. PMID 18484553 DOI: 10.1055/S-2008-1058110  0.661
2008 Leweke FM, Koethe D. Cannabis and psychiatric disorders: it is not only addiction. Addiction Biology. 13: 264-75. PMID 18482435 DOI: 10.1111/J.1369-1600.2008.00106.X  0.692
2008 Huang JT, Wang L, Prabakaran S, Wengenroth M, Lockstone HE, Koethe D, Gerth CW, Gross S, Schreiber D, Lilley K, Wayland M, Oxley D, Leweke FM, Bahn S. Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues. Molecular Psychiatry. 13: 1118-28. PMID 17938634 DOI: 10.1038/Sj.Mp.4002108  0.69
2007 Huang JT, Leweke FM, Tsang TM, Koethe D, Kranaster L, Gerth CW, Gross S, Schreiber D, Ruhrmann S, Schultze-Lutter F, Klosterkötter J, Holmes E, Bahn S. CSF metabolic and proteomic profiles in patients prodromal for psychosis. Plos One. 2: e756. PMID 17712404 DOI: 10.1371/Journal.Pone.0000756  0.723
2007 Schultze-Lutter F, Ruhrmann S, Hoyer C, Klosterkötter J, Leweke FM. The initial prodrome of schizophrenia: different duration, different underlying deficits? Comprehensive Psychiatry. 48: 479-88. PMID 17707258 DOI: 10.1016/J.Comppsych.2007.04.001  0.466
2007 Leweke FM, Giuffrida A, Koethe D, Schreiber D, Nolden BM, Kranaster L, Neatby MA, Schneider M, Gerth CW, Hellmich M, Klosterkötter J, Piomelli D. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. Schizophrenia Research. 94: 29-36. PMID 17566707 DOI: 10.1016/J.Schres.2007.04.025  0.705
2007 Koethe D, Dietl T, Leweke FM, Friess E. Cessation of complex visual hallucinations during treatment with mirtazapine. Pharmacopsychiatry. 40: 82-3. PMID 17447179 DOI: 10.1055/s-2007-961818  0.555
2007 Huang JT, McKenna T, Hughes C, Leweke FM, Schwarz E, Bahn S. CSF biomarker discovery using label-free nano-LC-MS based proteomic profiling: technical aspects. Journal of Separation Science. 30: 214-25. PMID 17390615 DOI: 10.1002/Jssc.200600350  0.396
2007 Koethe D, Llenos IC, Dulay JR, Hoyer C, Torrey EF, Leweke FM, Weis S. Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 1055-63. PMID 17370106 DOI: 10.1007/S00702-007-0660-5  0.672
2007 Leweke FM, Gerth CW, Koethe D, Nolden BM, Klosterkötter J. [Efficacy and tolerability of quetiapine in hospitalised schizophrenic patients during the acute treatment phase: a PMS study]. Fortschritte Der Neurologie-Psychiatrie. 75: 211-9. PMID 17230308 DOI: 10.1055/s-2006-954962  0.61
2007 Prabakaran S, Wengenroth M, Lockstone HE, Lilley K, Leweke FM, Bahn S. 2-D DIGE analysis of liver and red blood cells provides further evidence for oxidative stress in schizophrenia. Journal of Proteome Research. 6: 141-9. PMID 17203958 DOI: 10.1021/Pr060308A  0.477
2006 Huang JT, Leweke FM, Oxley D, Wang L, Harris N, Koethe D, Gerth CW, Nolden BM, Gross S, Schreiber D, Reed B, Bahn S. Disease biomarkers in cerebrospinal fluid of patients with first-onset psychosis. Plos Medicine. 3: e428. PMID 17090210 DOI: 10.1371/Journal.Pmed.0030428  0.719
2006 Koethe D, Gerth CW, Neatby MA, Haensel A, Thies M, Schneider U, Emrich HM, Klosterkötter J, Schultze-Lutter F, Leweke FM. Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness. Schizophrenia Research. 88: 142-50. PMID 17005373 DOI: 10.1016/J.Schres.2006.07.023  0.749
2006 Holmes E, Tsang TM, Huang JT, Leweke FM, Koethe D, Gerth CW, Nolden BM, Gross S, Schreiber D, Nicholson JK, Bahn S. Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. Plos Medicine. 3: e327. PMID 16933966 DOI: 10.1371/Journal.Pmed.0030327  0.732
2006 Grass G, Hellmich M, Leweke FM. Clozapine alone versus clozapine and risperidone for refractory schizophrenia. The New England Journal of Medicine. 354: 1846-8; author reply. PMID 16641404 DOI: 10.1056/NEJMc060588  0.375
2006 Emrich HM, Leweke FM, Schneider U. Systems-theory of psychosis--the relevance of "internal censorship". Pharmacopsychiatry. 39: S52-3. PMID 16508897 DOI: 10.1055/s-2006-931495  0.437
2006 Bahn S, Leweke FM, Huang JT. Profiling of CSF: Author's Reply Plos Medicine. 3: e468. DOI: 10.1371/Journal.Pmed.0030468  0.498
2004 Leweke FM, Gerth CW, Klosterkötter J. Cannabis-associated psychosis: current status of research. Cns Drugs. 18: 895-910. PMID 15521792 DOI: 10.2165/00023210-200418130-00005  0.512
2004 Giuffrida A, Leweke FM, Gerth CW, Schreiber D, Koethe D, Faulhaber J, Klosterkötter J, Piomelli D. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2108-14. PMID 15354183 DOI: 10.1038/Sj.Npp.1300558  0.752
2004 Leweke FM, Gerth CW, Koethe D, Faulhaber J, Klosterkotter J. Oxcarbazepine as an adjunct for schizophrenia. The American Journal of Psychiatry. 161: 1130-1. PMID 15169712 DOI: 10.1176/Appi.Ajp.161.6.1130-A  0.721
2004 Leweke FM, Gerth CW, Koethe D, Klosterkötter J, Ruslanova I, Krivogorsky B, Torrey EF, Yolken RH. Antibodies to infectious agents in individuals with recent onset schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 254: 4-8. PMID 14991372 DOI: 10.1007/S00406-004-0481-6  0.678
2002 Schneider U, Borsutzky M, Seifert J, Leweke FM, Huber TJ, Rollnik JD, Emrich HM. Reduced binocular depth inversion in schizophrenic patients. Schizophrenia Research. 53: 101-8. PMID 11728843 DOI: 10.1016/S0920-9964(00)00172-9  0.526
2000 Leweke FM, Schneider U, Radwan M, Schmidt E, Emrich HM. Different effects of nabilone and cannabidiol on binocular depth inversion in Man. Pharmacology, Biochemistry, and Behavior. 66: 175-81. PMID 10837858 DOI: 10.1016/S0091-3057(00)00201-X  0.523
1999 Leweke FM, Bauer J, Elger CE. Manic episode due to gabapentin treatment. The British Journal of Psychiatry : the Journal of Mental Science. 175: 291. PMID 10645343 DOI: 10.1192/bjp.175.3.291a  0.339
1999 Leweke FM, Giuffrida A, Wurster U, Emrich HM, Piomelli D. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. 10: 1665-9. PMID 10501554 DOI: 10.1097/00001756-199906030-00008  0.693
1999 Leweke FM, Emrich HM. Carbamazepine as an adjunct in the treatment of schizophrenia-like psychosis related to cannabis abuse. International Clinical Psychopharmacology. 14: 37-9. PMID 10221641  0.611
1999 Leweke FM, Schneider U, Thies M, Münte TF, Emrich HM. Effects of synthetic delta9-tetrahydrocannabinol on binocular depth inversion of natural and artificial objects in man. Psychopharmacology. 142: 230-5. PMID 10208314 DOI: 10.1007/S002130050884  0.434
1998 Schneider U, Leweke FM, Mueller-Vahl KR, Emrich HM. Cannabinoid/anandamide system and schizophrenia: is there evidence for association? Pharmacopsychiatry. 31: 110-3. PMID 9754842 DOI: 10.1055/S-2007-979355  0.55
1997 Sternemann U, Schneider U, Leweke FM, Bevilacqua CM, Dietrich DE, Emrich HM. [Pro-psychotic change of binocular depth inversion by sleep deprivation]. Der Nervenarzt. 68: 593-6. PMID 9333723 DOI: 10.1007/S001150050167  0.436
1997 Emrich HM, Leweke FM, Schneider U. Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system. Pharmacology, Biochemistry, and Behavior. 56: 803-7. PMID 9130308 DOI: 10.1016/S0091-3057(96)00426-1  0.53
1996 Schneider U, Leweke FM, Niemcyzk W, Sternemann U, Bevilacqua M, Emrich HM. Impaired binocular depth inversion in patients with alcohol withdrawal. Journal of Psychiatric Research. 30: 469-74. PMID 9023790  0.435
1996 Schneider U, Leweke FM, Sternemann U, Weber MM, Emrich HM. Visual 3D illusion: a systems-theoretical approach to psychosis. European Archives of Psychiatry and Clinical Neuroscience. 246: 256-60. PMID 8863004  0.48
1990 Leweke FM, Louvel J, Rausche G, Heinemann U. Effects of pentetrazol on neuronal activity and on extracellular calcium concentration in rat hippocampal slices. Epilepsy Research. 6: 187-98. PMID 2272342  0.327
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