| Year |
Citation |
Score |
| 2024 |
S Mesquita F, Abrami L, Linder ME, Bamji SX, Dickinson BC, van der Goot FG. Mechanisms and functions of protein S-acylation. Nature Reviews. Molecular Cell Biology. PMID 38355760 DOI: 10.1038/s41580-024-00700-8 |
0.371 |
|
| 2023 |
Nguyen PL, Greentree WK, Kawate T, Linder ME. GCP16 stabilizes the DHHC9 subfamily of protein acyltransferases through a conserved C-terminal cysteine motif. Frontiers in Physiology. 14: 1167094. PMID 37035671 DOI: 10.3389/fphys.2023.1167094 |
0.48 |
|
| 2021 |
Malgapo MIP, Linder ME. Substrate recruitment by zDHHC protein acyltransferases. Open Biology. 11: 210026. PMID 33878949 DOI: 10.1098/rsob.210026 |
0.485 |
|
| 2019 |
Malgapo MIP, Linder ME. Purification of Recombinant DHHC Proteins Using an Insect Cell Expression System. Methods in Molecular Biology (Clifton, N.J.). 2009: 179-189. PMID 31152404 DOI: 10.1007/978-1-4939-9532-5_14 |
0.438 |
|
| 2017 |
Gottlieb CD, Linder ME. Structure and function of DHHC protein S-acyltransferases. Biochemical Society Transactions. PMID 28630137 DOI: 10.1042/BST20160304 |
0.474 |
|
| 2016 |
Singh RR, Malgapo MI, Linder M, Daniel S. Single Particle Tracking in Double Cushioned, Blebbed Supported Lipid Bilayers Enables Studies of Transmembrane Protein Diffusion Biophysical Journal. 110: 568a. DOI: 10.1016/J.Bpj.2015.11.3042 |
0.477 |
|
| 2015 |
Gottlieb CD, Zhang S, Linder ME. The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc. The Journal of Biological Chemistry. 290: 29259-69. PMID 26487721 DOI: 10.1074/jbc.M115.691147 |
0.413 |
|
| 2014 |
Liu P, Jiao B, Linder M, Ren R. Abstract B49: Role of RAS palmitoyl-acyltransferase DHHC9 in hematopoiesis and NRAS leukemogenesis Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B49 |
0.365 |
|
| 2013 |
Hilgemann DW, Fine M, Linder ME, Jennings BC, Lin MJ. Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts. Elife. 2: e01293. PMID 24282236 DOI: 10.7554/Elife.01293 |
0.728 |
|
| 2013 |
Lai J, Linder ME. Oligomerization of DHHC protein S-acyltransferases. The Journal of Biological Chemistry. 288: 22862-70. PMID 23793055 DOI: 10.1074/jbc.M113.458794 |
0.405 |
|
| 2013 |
Nishimura A, Linder ME. Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding. Molecular and Cellular Biology. 33: 1417-29. PMID 23358418 DOI: 10.1128/MCB.01398-12 |
0.35 |
|
| 2013 |
Linder ME, Jennings BC. Mechanism and function of DHHC S-acyltransferases. Biochemical Society Transactions. 41: 29-34. PMID 23356254 DOI: 10.1042/Bst20120328 |
0.814 |
|
| 2012 |
Jennings BC, Linder ME. DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificities. The Journal of Biological Chemistry. 287: 7236-45. PMID 22247542 DOI: 10.1074/Jbc.M111.337246 |
0.801 |
|
| 2011 |
Hang HC, Linder ME. Exploring protein lipidation with chemical biology. Chemical Reviews. 111: 6341-58. PMID 21919527 DOI: 10.1021/Cr2001977 |
0.546 |
|
| 2011 |
Aittaleb M, Nishimura A, Linder ME, Tesmer JJ. Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells. The Journal of Biological Chemistry. 286: 34448-56. PMID 21832057 DOI: 10.1074/jbc.M111.273342 |
0.326 |
|
| 2011 |
Jia L, Linder ME, Blumer KJ. Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. The Journal of Biological Chemistry. 286: 13695-703. PMID 21343290 DOI: 10.1074/Jbc.M110.193763 |
0.337 |
|
| 2011 |
Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. FKBP12 binds to acylated H-ras and promotes depalmitoylation. Molecular Cell. 41: 173-85. PMID 21255728 DOI: 10.1016/J.Molcel.2011.01.001 |
0.714 |
|
| 2010 |
Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37. PMID 20460648 DOI: 10.1126/Scisignal.2000647 |
0.719 |
|
| 2010 |
Jennings BC, Linder ME. Regulation of g proteins by covalent modification Handbook of Cell Signaling, 2/E. 2: 1629-1633. DOI: 10.1016/B978-0-12-374145-5.00200-X |
0.786 |
|
| 2010 |
Linder ME. Lipid-mediated localization of signaling proteins Handbook of Cell Signaling, 2/E. 1: 365-371. DOI: 10.1016/B978-0-12-374145-5.00053-X |
0.496 |
|
| 2009 |
Nadolski MJ, Linder ME. Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3. The Journal of Biological Chemistry. 284: 17720-30. PMID 19416974 DOI: 10.1074/Jbc.M109.005447 |
0.807 |
|
| 2009 |
Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME. 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. Journal of Lipid Research. 50: 233-42. PMID 18827284 DOI: 10.1194/Jlr.M800270-Jlr200 |
0.739 |
|
| 2007 |
Nadolski MJ, Linder ME. Protein lipidation. The Febs Journal. 274: 5202-10. PMID 17892486 DOI: 10.1111/J.1742-4658.2007.06056.X |
0.818 |
|
| 2007 |
Linder ME, Deschenes RJ. Palmitoylation: policing protein stability and traffic. Nature Reviews. Molecular Cell Biology. 8: 74-84. PMID 17183362 DOI: 10.1038/Nrm2084 |
0.482 |
|
| 2006 |
Budde C, Schoenfish MJ, Linder ME, Deschenes RJ. Purification and characterization of recombinant protein acyltransferases. Methods (San Diego, Calif.). 40: 143-50. PMID 17012026 DOI: 10.1016/J.Ymeth.2006.07.017 |
0.49 |
|
| 2006 |
Linder M, Deschenes R. Protein palmitoylation. Methods (San Diego, Calif.). 40: 125-6. PMID 17012023 DOI: 10.1016/j.ymeth.2006.08.014 |
0.467 |
|
| 2006 |
Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/Jbc.M604428200 |
0.349 |
|
| 2006 |
Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ. Protein palmitoylation by a family of DHHC protein S-acyltransferases. Journal of Lipid Research. 47: 1118-27. PMID 16582420 DOI: 10.1194/Jlr.R600007-Jlr200 |
0.503 |
|
| 2006 |
Mittal V, Linder ME. Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A. The Biochemical Journal. 394: 309-15. PMID 16246175 DOI: 10.1042/Bj20051086 |
0.58 |
|
| 2005 |
Smotrys JE, Schoenfish MJ, Stutz MA, Linder ME. The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. The Journal of Cell Biology. 170: 1091-9. PMID 16186255 DOI: 10.1083/Jcb.200507048 |
0.784 |
|
| 2005 |
Swarthout JT, Lobo S, Farh L, Croke MR, Greentree WK, Deschenes RJ, Linder ME. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. The Journal of Biological Chemistry. 280: 31141-8. PMID 16000296 DOI: 10.1074/Jbc.M504113200 |
0.373 |
|
| 2005 |
Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/Jcb.200502007 |
0.356 |
|
| 2004 |
Mittal V, Linder ME. The RGS14 GoLoco domain discriminates among Galphai isoforms. The Journal of Biological Chemistry. 279: 46772-8. PMID 15337739 DOI: 10.1074/Jbc.M407409200 |
0.636 |
|
| 2004 |
Embry AC, Glick JL, Linder ME, Casey PJ. Reciprocal signaling between the transcriptional co-factor Eya2 and specific members of the Galphai family. Molecular Pharmacology. 66: 1325-31. PMID 15308761 DOI: 10.1124/Mol.104.004093 |
0.633 |
|
| 2004 |
Smotrys JE, Linder ME. Palmitoylation of intracellular signaling proteins: regulation and function. Annual Review of Biochemistry. 73: 559-87. PMID 15189153 DOI: 10.1146/Annurev.Biochem.73.011303.073954 |
0.784 |
|
| 2004 |
Linder ME, Deschenes RJ. Model organisms lead the way to protein palmitoyltransferases. Journal of Cell Science. 117: 521-6. PMID 14730009 DOI: 10.1242/Jcs.00989 |
0.489 |
|
| 2004 |
Bernstein LS, Linder ME, Hepler JR. Analysis of RGS protein palmitoylation. Methods in Molecular Biology (Clifton, N.J.). 237: 195-204. PMID 14501051 DOI: 10.1385/1-59259-430-1:195 |
0.8 |
|
| 2004 |
Greentree WK, Linder ME. Purification of recombinant G protein alpha subunits from Escherichia coli. Methods in Molecular Biology (Clifton, N.J.). 237: 3-20. PMID 14501035 DOI: 10.1385/1-59259-430-1:3 |
0.372 |
|
| 2004 |
Linder M, Rudnick D. Protein N-myristoyltransferase 1 Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A000095.01 |
0.46 |
|
| 2003 |
Linder ME, Deschenes RJ. New insights into the mechanisms of protein palmitoylation. Biochemistry. 42: 4311-20. PMID 12693927 DOI: 10.1021/Bi034159A |
0.515 |
|
| 2002 |
Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE. Distinct sites on G protein beta gamma subunits regulate different effector functions. The Journal of Biological Chemistry. 277: 36345-50. PMID 12124391 DOI: 10.1074/Jbc.M205359200 |
0.516 |
|
| 2002 |
Loranger SS, Linder ME. SNAP-25 traffics to the plasma membrane by a syntaxin-independent mechanism. The Journal of Biological Chemistry. 277: 34303-9. PMID 12114505 DOI: 10.1074/Jbc.M202125200 |
0.781 |
|
| 2001 |
Dunphy JT, Greentree WK, Linder ME. Enrichment of G-protein palmitoyltransferase activity in low density membranes: in vitro reconstitution of Galphai to these domains requires palmitoyltransferase activity. The Journal of Biological Chemistry. 276: 43300-4. PMID 11557754 DOI: 10.1074/jbc.M104275200 |
0.436 |
|
| 2001 |
Fogg VC, Azpiazu I, Linder ME, Smrcka A, Scarlata S, Gautam N. Role of the gamma subunit prenyl moiety in G protein beta gamma complex interaction with phospholipase Cbeta. The Journal of Biological Chemistry. 276: 41797-802. PMID 11546822 DOI: 10.1074/Jbc.M107661200 |
0.305 |
|
| 2001 |
Linder ME. 8 Reversible modification of proteins with thioester-linked fatty acids Enzymes. 21: 215-240. DOI: 10.1016/S1874-6047(01)80021-4 |
0.329 |
|
| 2000 |
Dunphy JT, Schroeder H, Leventis R, Greentree WK, Knudsen JK, Silvius JR, Linder ME. Differential effects of acyl-CoA binding protein on enzymatic and non- enzymatic thioacylation of protein and peptide substrates Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1485: 185-198. PMID 10832099 DOI: 10.1016/S1388-1981(00)00060-3 |
0.455 |
|
| 2000 |
Bernstein LS, Grillo AA, Loranger SS, Linder ME. RGS4 binds to membranes through an amphipathic alpha -helix. The Journal of Biological Chemistry. 275: 18520-6. PMID 10764749 DOI: 10.1074/Jbc.M000618200 |
0.779 |
|
| 2000 |
Manahan CL, Patnana M, Blumer KJ, Linder ME. Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 11: 957-68. PMID 10712512 DOI: 10.1091/Mbc.11.3.957 |
0.414 |
|
| 2000 |
Moffett S, Brown DA, Linder ME. Lipid-dependent targeting of G proteins into rafts. The Journal of Biological Chemistry. 275: 2191-8. PMID 10636925 DOI: 10.1074/jbc.275.3.2191 |
0.409 |
|
| 1999 |
Azpiazu I, Cruzblanca H, Li P, Linder M, Zhuo M, Gautam N. A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling. The Journal of Biological Chemistry. 274: 35305-8. PMID 10585394 DOI: 10.1074/Jbc.274.50.35305 |
0.4 |
|
| 1999 |
Heximer SP, Srinivasa SP, Bernstein LS, Bernard JL, Linder ME, Hepler JR, Blumer KJ. G protein selectivity is a determinant of RGS2 function. The Journal of Biological Chemistry. 274: 34253-9. PMID 10567399 DOI: 10.1074/Jbc.274.48.34253 |
0.762 |
|
| 1999 |
Gonzalo S, Greentree WK, Linder ME. SNAP-25 is targeted to the plasma membrane through a novel membrane- binding domain Journal of Biological Chemistry. 274: 21313-21318. PMID 10409690 DOI: 10.1074/Jbc.274.30.21313 |
0.36 |
|
| 1998 |
Dunphy JT, Linder ME. Signalling functions of protein palmitoylation Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1436: 245-261. PMID 9838145 DOI: 10.1016/S0005-2760(98)00130-1 |
0.51 |
|
| 1998 |
Srinivasa SP, Bernstein LS, Blumer KJ, Linder ME. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 95: 5584-9. PMID 9576926 DOI: 10.1073/Pnas.95.10.5584 |
0.676 |
|
| 1998 |
Gonzalo S, Linder ME. SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway Molecular Biology of the Cell. 9: 585-597. PMID 9487128 DOI: 10.1091/Mbc.9.3.585 |
0.383 |
|
| 1997 |
Heximer SP, Watson N, Linder ME, Blumer KJ, Hepler JR. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proceedings of the National Academy of Sciences of the United States of America. 94: 14389-93. PMID 9405622 DOI: 10.1073/Pnas.94.26.14389 |
0.705 |
|
| 1997 |
Linder ME, Gonzalo S. Palmitoylation of SNAP-25 is required for membrane targeting but not stable membrane association Faseb Journal. 11. |
0.406 |
|
| 1996 |
Cohen NA, Sha Q, Makhina EN, Lopatin AN, Linder ME, Snyder SH, Nichols CG. Inhibition of an inward rectifier potassium channel (Kir2.3) by G-protein betagamma subunits. The Journal of Biological Chemistry. 271: 32301-5. PMID 8943291 DOI: 10.1074/Jbc.271.50.32301 |
0.404 |
|
| 1996 |
Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature. 383: 172-5. PMID 8774882 DOI: 10.1038/383172A0 |
0.38 |
|
| 1996 |
Dunphy JT, Greentree WK, Manahan CL, Linder ME. G-protein palmitoyltransferase activity is enriched in plasma membranes. The Journal of Biological Chemistry. 271: 7154-9. PMID 8636152 DOI: 10.1074/jbc.271.12.7154 |
0.458 |
|
| 1995 |
Linder ME, Kleuss C, Mumby SM. Palmitoylation of G-protein alpha subunits. Methods in Enzymology. 250: 314-30. PMID 7651161 DOI: 10.1016/0076-6879(95)50081-2 |
0.341 |
|
| 1994 |
Fields TA, Linder ME, Casey PJ. Subtype-specific binding of azidoanilido-GTP by purified G protein α subunits Biochemistry. 33: 6877-6883. PMID 8204622 DOI: 10.1021/Bi00188A017 |
0.586 |
|
| 1994 |
Coleman DE, Lee E, Mixon MB, Linder ME, Berghuis AM, Gilman AG, Sprang SR. Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states. Journal of Molecular Biology. 238: 630-4. PMID 8176751 DOI: 10.1006/Jmbi.1994.1320 |
0.681 |
|
| 1994 |
Wickman KD, Iñiguez-Lluhl JA, Davenport PA, Taussig R, Krapivinsky GB, Linder ME, Gilman AG, Clapham DE. Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel. Nature. 368: 255-7. PMID 8145826 DOI: 10.1038/368255A0 |
0.557 |
|
| 1994 |
Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science (New York, N.Y.). 265: 1405-12. PMID 8073283 DOI: 10.1126/Science.8073283 |
0.706 |
|
| 1994 |
Mumby SM, Linder ME. [20] Myristoylation of G-protein α subunits Methods in Enzymology. 237: 254-268. PMID 7935001 DOI: 10.1016/S0076-6879(94)37067-2 |
0.309 |
|
| 1994 |
Lee E, Linder ME, Gilman AG. [12] Expression of G-protein α subunits in Escherichia coli Methods in Enzymology. 237: 146-154. PMID 7934993 DOI: 10.1016/S0076-6879(94)37059-1 |
0.759 |
|
| 1993 |
Linder ME, Middleton P, Hepler JR, Taussig R, Gilman AG, Mumby SM. Lipid modifications of G proteins: alpha subunits are palmitoylated. Proceedings of the National Academy of Sciences of the United States of America. 90: 3675-9. PMID 8475115 DOI: 10.1073/Pnas.90.8.3675 |
0.703 |
|
| 1992 |
Linder ME, Gilman AG. G proteins. Scientific American. 267: 56-61, 64-5. PMID 1502510 |
0.617 |
|
| 1992 |
Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Tyrosine phosphorylation of G protein α subunits by pp60c-src Proceedings of the National Academy of Sciences of the United States of America. 89: 5720-5724. PMID 1378615 DOI: 10.1073/Pnas.89.13.5720 |
0.397 |
|
| 1991 |
Linder ME, Gilman AG. Purification of recombinant Gi alpha and Go alpha proteins from Escherichia coli. Methods in Enzymology. 195: 202-15. PMID 1903487 DOI: 10.1016/0076-6879(91)95167-I |
0.548 |
|
| 1991 |
Rubenstein RC, Linder ME, Ross EM. Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles. Biochemistry. 30: 10769-77. PMID 1657154 DOI: 10.1021/Bi00108A023 |
0.549 |
|
| 1990 |
Duronio RJ, Rudnick DA, Johnson RL, Linder ME, Gordon JI. Reconstitution of protein N-myristoylation in Escherichia coli Methods. 1: 253-263. DOI: 10.1016/S1046-2023(05)80325-1 |
0.355 |
|
| 1988 |
Linder ME, Burr JG. Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 85: 2608-2612. PMID 2451829 DOI: 10.1073/pnas.85.8.2608 |
0.383 |
|
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