| Year |
Citation |
Score |
| 2024 |
Wang Y, Liu Y, Xiang G, Jian Y, Yang Z, Chen T, Ma X, Zhao N, Dai Y, Lv Y, Wang H, He L, Shi B, Liu Q, Liu Y, ... Otto M, et al. Post-translational toxin modification by lactate controls Staphylococcus aureus virulence. Nature Communications. 15: 9835. PMID 39537625 DOI: 10.1038/s41467-024-53979-8 |
0.371 |
|
| 2024 |
Yamazaki Y, Ito T, Nakagawa S, Sugihira T, Kurita-Tachibana C, Villaruz AE, Ishiguro K, Salcman B, Li S, Takada S, Inohara N, Kusuya Y, Shibata A, Tamai M, Aoyama R, ... ... Otto M, et al. Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment. Nature Communications. 15: 9619. PMID 39511195 DOI: 10.1038/s41467-024-54033-3 |
0.357 |
|
| 2024 |
Piewngam P, Otto M. Staphylococcus aureus colonisation and strategies for decolonisation. The Lancet. Microbe. PMID 38518792 DOI: 10.1016/S2666-5247(24)00040-5 |
0.417 |
|
| 2024 |
Cheung GYC, Lee JH, Liu R, Lawhon SD, Yang C, Otto M. Methicillin Resistance Elements in the Canine Pathogen and Their Association with the Peptide Toxin PSM-mec. Antibiotics (Basel, Switzerland). 13. PMID 38391516 DOI: 10.3390/antibiotics13020130 |
0.322 |
|
| 2024 |
Le KY, Otto M. Approaches to combating methicillin-resistant (MRSA) biofilm infections. Expert Opinion On Investigational Drugs. 1-3. PMID 38205812 DOI: 10.1080/13543784.2024.2305136 |
0.381 |
|
| 2023 |
Cheung GYC, Otto M. Virulence Mechanisms of Staphylococcal Animal Pathogens. International Journal of Molecular Sciences. 24. PMID 37834035 DOI: 10.3390/ijms241914587 |
0.412 |
|
| 2023 |
Heinzinger LR, Pugh AR, Wagner JA, Otto M. Evaluating the Translational Potential of Bacteriocins as an Alternative Treatment for Infections in Animals and Humans. Antibiotics (Basel, Switzerland). 12. PMID 37627676 DOI: 10.3390/antibiotics12081256 |
0.39 |
|
| 2023 |
Hsieh RC, Liu R, Burgin DJ, Otto M. Understanding mechanisms of virulence in MRSA: implications for anti-virulence treatment strategies. Expert Review of Anti-Infective Therapy. PMID 37501364 DOI: 10.1080/14787210.2023.2242585 |
0.363 |
|
| 2023 |
Otto M, Dickey SW, Wolz C. Editorial: Quorum-sensing in Gram-positive pathogens - mechanisms, role in infection, and potential as a therapeutic target. Frontiers in Cellular and Infection Microbiology. 13: 1236705. PMID 37404725 DOI: 10.3389/fcimb.2023.1236705 |
0.319 |
|
| 2023 |
Douglas EJA, Palk N, Brignoli T, Altwiley D, Boura M, Laabei M, Recker M, Cheung GCY, Liu R, Hseih RC, Otto M, O'Brien E, McLoughlin RM, Massey RC. Extensive remodelling of the cell wall during the development of bacteraemia. Elife. 12. PMID 37401629 DOI: 10.7554/eLife.87026 |
0.342 |
|
| 2023 |
He L, Lv H, Wang Y, Jiang F, Liu Q, Zhang F, Wang H, Shen H, Otto M, Li M. Antibiotic treatment can exacerbate biofilm-associated infection by promoting quorum cheater development. Npj Biofilms and Microbiomes. 9: 26. PMID 37202425 DOI: 10.1038/s41522-023-00394-4 |
0.408 |
|
| 2023 |
Breed MW, Perez HL, Otto M, Villaruz AE, Weese JS, Alvord GW, Donohue DE, Washington F, Kramer JA. Bacterial Genotype, Carrier Risk Factors, and an Antimicrobial Stewardship Approach Relevant to Methicillin-resistant Prevalence in a Population of Macaques Housed in a Research Facility. Comparative Medicine. PMID 36941053 DOI: 10.30802/AALAS-CM-22-000018 |
0.34 |
|
| 2023 |
Douglas EJA, Palk N, Brignoli T, Altwiley D, Boura M, Laabei M, Recker M, Cheung GYC, Liu R, Hsieh RC, Otto M, Oâ Brien E, McLoughlin RM, Massey RC. Extensive re-modelling of the cell wall during the development of bacteraemia. Biorxiv : the Preprint Server For Biology. PMID 36865143 DOI: 10.1101/2023.02.23.529713 |
0.343 |
|
| 2023 |
Otto M. Critical Assessment of the Prospects of Quorum-Quenching Therapy for Infection. International Journal of Molecular Sciences. 24. PMID 36835436 DOI: 10.3390/ijms24044025 |
0.386 |
|
| 2023 |
Piewngam P, Khongthong S, Roekngam N, Theapparat Y, Sunpaweravong S, Faroongsarng D, Otto M. Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand: a phase 2, double-blind, randomised, placebo-controlled trial. The Lancet. Microbe. PMID 36646104 DOI: 10.1016/S2666-5247(22)00322-6 |
0.405 |
|
| 2022 |
Zheng Y, Hunt RL, Villaruz AE, Fisher EL, Liu R, Liu Q, Cheung GYC, Li M, Otto M. Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides. Cell Host & Microbe. PMID 35123653 DOI: 10.1016/j.chom.2022.01.004 |
0.596 |
|
| 2022 |
Joubert IA, Otto M, Strunk T, Currie AJ. Look Who's Talking: Host and Pathogen Drivers of Virulence in Neonatal Sepsis. International Journal of Molecular Sciences. 23. PMID 35055041 DOI: 10.3390/ijms23020860 |
0.325 |
|
| 2021 |
Nguyen TH, Cheung GYC, Rigby KM, Kamenyeva O, Kabat J, Sturdevant DE, Villaruz AE, Liu R, Piewngam P, Porter AR, Firdous S, Chiou J, Park MD, Hunt RL, Almufarriji FMF, ... ... Otto M, et al. Rapid pathogen-specific recruitment of immune effector cells in the skin by secreted toxins. Nature Microbiology. PMID 34873293 DOI: 10.1038/s41564-021-01012-9 |
0.746 |
|
| 2021 |
Rungelrath V, Porter AR, Malachowa N, Freedman BA, Leung JM, Voyich JM, Otto M, Kobayashi SD, DeLeo FR. Further Insight into the Mechanism of Human PMN Lysis following Phagocytosis of Staphylococcus aureus. Microbiology Spectrum. 9: e0088821. PMID 34704790 DOI: 10.1128/Spectrum.00888-21 |
0.646 |
|
| 2021 |
Knott S, Curry D, Zhao N, Metgud P, Dastgheyb SS, Purtill C, Harwood M, Chen AF, Schaer TP, Otto M, Hickok NJ. Floating Biofilm Formation and Phenotype in Synovial Fluid Depends on Albumin, Fibrinogen, and Hyaluronic Acid. Frontiers in Microbiology. 12: 655873. PMID 33995317 DOI: 10.3389/fmicb.2021.655873 |
0.305 |
|
| 2021 |
Matsumoto M, Nakagawa S, Zhang L, Nakamura Y, Villaruz AE, Otto M, Wolz C, Inohara N, Núñez G. Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin. Cell Host & Microbe. PMID 33852876 DOI: 10.1016/j.chom.2021.03.007 |
0.359 |
|
| 2021 |
Cheung GYC, Bae JS, Liu R, Hunt RL, Zheng Y, Otto M. Bacterial virulence plays a crucial role in MRSA sepsis. Plos Pathogens. 17: e1009369. PMID 33630954 DOI: 10.1371/journal.ppat.1009369 |
0.7 |
|
| 2021 |
Cheung GYC, Bae JS, Otto M. Pathogenicity and virulence of . Virulence. 12: 547-569. PMID 33522395 DOI: 10.1080/21505594.2021.1878688 |
0.382 |
|
| 2020 |
Nguyen HTT, Nguyen TH, Otto M. The staphylococcal exopolysaccharide PIA - Biosynthesis and role in biofilm formation, colonization, and infection. Computational and Structural Biotechnology Journal. 18: 3324-3334. PMID 33240473 DOI: 10.1016/j.csbj.2020.10.027 |
0.4 |
|
| 2020 |
Bae JS, Da F, Liu R, He L, Lv H, Fisher EL, Rajagopalan G, Li M, Cheung GYC, Otto M. Staphylococcal enterotoxin B contributes to Staphylococcus aureus systemic infection. The Journal of Infectious Diseases. PMID 32937658 DOI: 10.1093/Infdis/Jiaa584 |
0.551 |
|
| 2020 |
Duggan S, Laabei M, Alnahari A, O'Brien EC, Lacey KA, Bacon L, Heesom K, Fu CL, Otto M, Skaar E, McLoughlin RM, Massey RC. A small membrane stabilising protein critical to the pathogenicity of Infection and Immunity. PMID 32571989 DOI: 10.1128/Iai.00162-20 |
0.468 |
|
| 2020 |
Liu Y, Liu Y, Du Z, Zhang L, Chen J, Shen Z, Liu Q, Qin J, Lv H, Wang H, He L, Liu J, Huang Q, Sun Y, Otto M, et al. Skin microbiota analysis-inspired development of novel anti-infectives. Microbiome. 8: 85. PMID 32503672 DOI: 10.1186/S40168-020-00866-1 |
0.436 |
|
| 2020 |
Otto M. Staphylococci in the human microbiome: the role of host and interbacterial interactions. Current Opinion in Microbiology. 53: 71-77. PMID 32298967 DOI: 10.1016/J.Mib.2020.03.003 |
0.437 |
|
| 2020 |
Piewngam P, Chiou J, Chatterjee P, Otto M. Alternative approaches to treat bacterial infections: targeting quorum-sensing. Expert Review of Anti-Infective Therapy. PMID 32243194 DOI: 10.1080/14787210.2020.1750951 |
0.459 |
|
| 2020 |
Leite EL, Gautron A, Deplanche M, Nicolas A, Ossemond J, Nguyen MT, do Carmo FLR, Gilot D, Azevedo V, Goetz F, Le Loir Y, Otto M, Berkova N. Involvement of caspase-1 in inflammasomes activation and bacterial clearance in S. aureus-infected osteoblasts-like MG-63 cells. Cellular Microbiology. e13204. PMID 32176433 DOI: 10.1111/Cmi.13204 |
0.42 |
|
| 2020 |
Otto M. Staphylococcus colonization of the skin and antimicrobial peptides. Expert Review of Dermatology. 5: 183-195. PMID 20473345 DOI: 10.1586/Edm.10.6 |
0.479 |
|
| 2019 |
Liu Q, Liu Q, Meng H, Lv H, Liu Y, Liu J, Wang H, He L, Qin J, Wang Y, Dai Y, Otto M, Li M. Staphylococcus epidermidis Contributes to Healthy Maturation of the Nasal Microbiome by Stimulating Antimicrobial Peptide Production. Cell Host & Microbe. PMID 31866425 DOI: 10.1016/J.Chom.2019.11.003 |
0.504 |
|
| 2019 |
Deplanche M, Mouhali N, Nguyen MT, Cauty C, Ezan F, Diot A, Raulin L, Dutertre S, Langouet S, Legembre P, Taieb F, Otto M, Laurent F, Götz F, Le Loir Y, et al. Staphylococcus aureus induces DNA damage in host cell. Scientific Reports. 9: 7694. PMID 31118484 DOI: 10.1038/S41598-019-44213-3 |
0.376 |
|
| 2019 |
Le KY, Villaruz AE, Zheng Y, He L, Fisher EL, Nguyen TH, Ho TV, Yeh AJ, Joo HS, Cheung GYC, Otto M. Role of Phenol-Soluble Modulins in Staphylococcus epidermidis Biofilm Formation and Infection of Indwelling Medical Devices. Journal of Molecular Biology. PMID 30954574 DOI: 10.1016/J.Jmb.2019.03.030 |
0.465 |
|
| 2019 |
He L, Le KY, Khan BA, Nguyen TH, Hunt RL, Bae JS, Kabat J, Zheng Y, Cheung GYC, Li M, Otto M. Resistance to leukocytes ties benefits of quorum sensing dysfunctionality to biofilm infection. Nature Microbiology. PMID 30936487 DOI: 10.1038/S41564-019-0413-X |
0.724 |
|
| 2019 |
Piewngam P, Otto M. Probiotics to prevent Staphylococcus aureus disease? Gut Microbes. 1-8. PMID 30913972 DOI: 10.1080/19490976.2019.1591137 |
0.501 |
|
| 2019 |
Raafat D, Otto M, Reppschläger K, Iqbal J, Holtfreter S. Fighting Staphylococcus aureus Biofilms with Monoclonal Antibodies. Trends in Microbiology. PMID 30665698 DOI: 10.1016/J.Tim.2018.12.009 |
0.468 |
|
| 2019 |
Hardy BL, Dickey SW, Plaut RD, Riggins DP, Stibitz S, Otto M, Merrell DS. Corynebacterium pseudodiphtheriticum Exploits Staphylococcus aureus Virulence Components in a Novel Polymicrobial Defense Strategy. Mbio. 10. PMID 30622190 DOI: 10.1128/Mbio.02491-18 |
0.49 |
|
| 2019 |
Chang S, Fowler VG, Sharma-Kuinkel BK, Medie F, Park L, Zheng Y, Otto M, Horswill A. 2594. Biofilm-Dispersed Staphylococcus aureus Exhibits a Distinct agr-Independent Host Interaction Open Forum Infectious Diseases. 6: S901-S902. DOI: 10.1093/Ofid/Ofz360.2272 |
0.416 |
|
| 2018 |
Piewngam P, Quiñones M, Thirakittiwatthana W, Yungyuen T, Otto M, Kiratisin P. Composition of the intestinal microbiota in extended-spectrum β-lactamase-producing Enterobacteriaceae carriers and non-carriers in Thailand. International Journal of Antimicrobial Agents. PMID 30578963 DOI: 10.1016/J.Ijantimicag.2018.12.006 |
0.333 |
|
| 2018 |
Schlatterer K, Beck C, Hanzelmann D, Lebtig M, Fehrenbacher B, Schaller M, Ebner P, Nega M, Otto M, Kretschmer D, Peschel A. The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus. Mbio. 9. PMID 30459192 DOI: 10.1128/Mbio.01851-18 |
0.333 |
|
| 2018 |
Piewngam P, Zheng Y, Nguyen TH, Dickey SW, Joo HS, Villaruz AE, Glose KA, Fisher EL, Hunt RL, Li B, Chiou J, Pharkjaksu S, Khongthong S, Cheung GYC, Kiratisin P, ... Otto M, et al. Pathogen elimination by probiotic Bacillus via signalling interference. Nature. PMID 30305736 DOI: 10.1038/S41586-018-0616-Y |
0.719 |
|
| 2018 |
Otto M. Staphylococcal Biofilms. Microbiology Spectrum. 6. PMID 30117414 DOI: 10.1128/microbiolspec.GPP3-0023-2018 |
0.383 |
|
| 2018 |
Cheung GY, Otto M. Do antimicrobial peptides and antimicrobial-peptide resistance play important roles during bacterial infection? Future Microbiology. PMID 30113237 DOI: 10.2217/Fmb-2018-0138 |
0.421 |
|
| 2018 |
Fisher EL, Otto M, Cheung GYC. Basis of Virulence in Enterotoxin-Mediated Staphylococcal Food Poisoning. Frontiers in Microbiology. 9: 436. PMID 29662470 DOI: 10.3389/Fmicb.2018.00436 |
0.335 |
|
| 2018 |
Zheng Y, He L, Asiamah TK, Otto M. Colonization of Medical Devices by Staphylococci. Environmental Microbiology. PMID 29633455 DOI: 10.1111/1462-2920.14129 |
0.401 |
|
| 2018 |
Le KY, Park MD, Otto M. Immune Evasion Mechanisms ofBiofilm Infection. Frontiers in Microbiology. 9: 359. PMID 29541068 DOI: 10.3389/Fmicb.2018.00359 |
0.48 |
|
| 2018 |
Nakatsuji T, Chen TH, Butcher AM, Trzoss LL, Nam SJ, Shirakawa KT, Zhou W, Oh J, Otto M, Fenical W, Gallo RL. A commensal strain ofprotects against skin neoplasia. Science Advances. 4: eaao4502. PMID 29507878 DOI: 10.1126/Sciadv.Aao4502 |
0.367 |
|
| 2018 |
He L, Zheng HX, Wang Y, Le KY, Liu Q, Shang J, Dai Y, Meng H, Wang X, Li T, Gao Q, Qin J, Lu H, Otto M, Li M. Detection and analysis of methicillin-resistant human-adapted sequence type 398 allows insight into community-associated methicillin-resistant Staphylococcus aureus evolution. Genome Medicine. 10: 5. PMID 29378646 DOI: 10.1186/S13073-018-0514-9 |
0.502 |
|
| 2018 |
Cheung GYC, Fisher EL, McCausland JW, Choi J, Collins JWM, Dickey SW, Otto M. Antimicrobial peptide resistance mechanism contributes to Staphylococcus aureus infection. The Journal of Infectious Diseases. PMID 29351622 DOI: 10.1093/Infdis/Jiy024 |
0.533 |
|
| 2018 |
Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP. Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction. Science Translational Medicine. 10. PMID 29343625 DOI: 10.1126/Scitranslmed.Aam7964 |
0.472 |
|
| 2018 |
Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM. Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314. Nature Communications. 9: 37. PMID 29295977 DOI: 10.1038/S41467-017-02448-6 |
0.324 |
|
| 2017 |
Nakagawa S, Matsumoto M, Katayama Y, Oguma R, Wakabayashi S, Nygaard T, Saijo S, Inohara N, Otto M, Matsue H, Núñez G, Nakamura Y. Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation. Cell Host & Microbe. 22: 667-677.e5. PMID 29120744 DOI: 10.1016/J.Chom.2017.10.008 |
0.307 |
|
| 2017 |
Dickey SW, Otto M. Lipoyl-E2-PDH Gets a Second Job. Cell Host & Microbe. 22: 581-583. PMID 29120739 DOI: 10.1016/J.Chom.2017.10.018 |
0.37 |
|
| 2017 |
Zheng Y, Joo HS, Nair V, Le KY, Otto M. Do amyloid structures formed by Staphylococcus aureus phenol-soluble modulins have a biological function? International Journal of Medical Microbiology : Ijmm. PMID 28867522 DOI: 10.1016/J.Ijmm.2017.08.010 |
0.335 |
|
| 2017 |
Ebner P, Luqman A, Reichert S, Hauf K, Popella P, Forchhammer K, Otto M, Götz F. Non-classical Protein Excretion Is Boosted by PSMα-Induced Cell Leakage. Cell Reports. 20: 1278-1286. PMID 28793253 DOI: 10.1016/J.Celrep.2017.07.045 |
0.333 |
|
| 2017 |
Otto M. Staphylococcus epidermidis: a major player in bacterial sepsis? Future Microbiology. PMID 28748707 DOI: 10.2217/Fmb-2017-0143 |
0.478 |
|
| 2017 |
Otto M. Next-generation sequencing to monitor the spread of antimicrobial resistance. Genome Medicine. 9: 68. PMID 28738906 DOI: 10.1186/S13073-017-0461-X |
0.39 |
|
| 2017 |
Da F, Joo HS, Cheung GYC, Villaruz AE, Rohde H, Luo X, Otto M. Phenol-Soluble Modulin Toxins of Staphylococcus haemolyticus. Frontiers in Cellular and Infection Microbiology. 7: 206. PMID 28596942 DOI: 10.3389/Fcimb.2017.00206 |
0.487 |
|
| 2017 |
Nguyen TH, Park MD, Otto M. Host Response to Staphylococcus epidermidis Colonization and Infections. Frontiers in Cellular and Infection Microbiology. 7: 90. PMID 28377905 DOI: 10.3389/Fcimb.2017.00090 |
0.524 |
|
| 2017 |
Dickey SW, Cheung GY, Otto M. Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nature Reviews. Drug Discovery. PMID 28337021 DOI: 10.1038/Nrd.2017.23 |
0.47 |
|
| 2017 |
Qin L, Da F, Fisher EL, Tan DC, Nguyen TH, Fu CL, Tan VY, McCausland JW, Sturdevant DE, Joo HS, Queck SY, Cheung GY, Otto M. Toxin Mediates Sepsis Caused by Methicillin-Resistant Staphylococcus epidermidis. Plos Pathogens. 13: e1006153. PMID 28151994 DOI: 10.1371/Journal.Ppat.1006153 |
0.558 |
|
| 2016 |
Joo HS, Otto M. Toxin-mediated gene regulatory mechanism in Staphylococcus aureus. Microbial Cell (Graz, Austria). 4: 29-31. PMID 28357385 DOI: 10.15698/Mic2017.01.553 |
0.458 |
|
| 2016 |
Joo HS, Chatterjee SS, Villaruz AE, Dickey SW, Tan VY, Chen Y, Sturdevant DE, Ricklefs SM, Otto M. Mechanism of Gene Regulation by a Staphylococcus aureus Toxin. Mbio. 7. PMID 27795396 DOI: 10.1128/Mbio.01579-16 |
0.427 |
|
| 2016 |
Li M, Wang Y, Zhu Y, Dai Y, Hong X, Liu Q, Li T, Qin J, Ma X, Lu H, Xu J, Otto M. Increased Community-Associated Infections Caused by Panton-Valentine Leukocidin-Negative MRSA, Shanghai, 2005-2014. Emerging Infectious Diseases. 22: 1988-1991. PMID 27767912 DOI: 10.3201/eid2211.160587 |
0.385 |
|
| 2016 |
Nygaard TK, Kobayashi SD, Freedman B, Porter AR, Voyich JM, Otto M, Schneewind O, DeLeo FR. Interaction of Staphylococci with Human B cells. Plos One. 11: e0164410. PMID 27711145 DOI: 10.1371/Journal.Pone.0164410 |
0.622 |
|
| 2016 |
Mansour SC, Pletzer D, de la Fuente-Núñez C, Kim P, Cheung GY, Joo HS, Otto M, Hancock RE. Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically. Ebiomedicine. PMID 27658736 DOI: 10.1016/J.Ebiom.2016.09.015 |
0.485 |
|
| 2016 |
Qin L, McCausland JW, Cheung GY, Otto M. PSM-Mec-A Virulence Determinant that Connects Transcriptional Regulation, Virulence, and Antibiotic Resistance in Staphylococci. Frontiers in Microbiology. 7: 1293. PMID 27597849 DOI: 10.3389/Fmicb.2016.01293 |
0.464 |
|
| 2016 |
Hanzelmann D, Joo HS, Franz-Wachtel M, Hertlein T, Stevanovic S, Macek B, Wolz C, Götz F, Otto M, Kretschmer D, Peschel A. Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants. Nature Communications. 7: 12304. PMID 27470911 DOI: 10.1038/Ncomms12304 |
0.427 |
|
| 2016 |
Surewaard BG, Deniset JF, Zemp FJ, Amrein M, Otto M, Conly J, Omri A, Yates RM, Kubes P. Identification and treatment of the Staphylococcus aureus reservoir in vivo. The Journal of Experimental Medicine. PMID 27325887 DOI: 10.1084/Jem.20160334 |
0.475 |
|
| 2016 |
Li M, Dai Y, Zhu Y, Fu CL, Tan VY, Wang Y, Wang X, Hong X, Liu Q, Li T, Qin J, Ma X, Fang J, Otto M. Virulence determinants associated with the Asian community-associated methicillin-resistant Staphylococcus aureus lineage ST59. Scientific Reports. 6: 27899. PMID 27296890 DOI: 10.1038/Srep27899 |
0.468 |
|
| 2016 |
Joo HS, Fu CI, Otto M. Bacterial strategies of resistance to antimicrobial peptides. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 371. PMID 27160595 DOI: 10.1098/Rstb.2015.0292 |
0.467 |
|
| 2016 |
Wang Y, Hu M, Liu Q, Qin J, Dai Y, He L, Li T, Zheng B, Zhou F, Yu K, Fang J, Liu X, Otto M, Li M. Role of the ESAT-6 secretion system in virulence of the emerging community-associated Staphylococcus aureus lineage ST398. Scientific Reports. 6: 25163. PMID 27112266 DOI: 10.1038/Srep25163 |
0.554 |
|
| 2016 |
Deplanche M, Alekseeva L, Semenovskaya K, Fu CL, Dessauge F, Finot L, Petzl W, Zerbe H, Le Loir Y, Rainard P, Smith DG, Germon P, Otto M, Berkova N. Staphylococcus aureus phenol-soluble modulins impair interleukin expression in bovine mammary epithelial cells. Infection and Immunity. PMID 27001539 DOI: 10.1128/Iai.01330-15 |
0.359 |
|
| 2016 |
Qi R, Joo HS, Sharma-Kuinkel B, Berlon NR, Park L, Fu CL, Messina JA, Thaden JT, Yan Q, Ruffin F, Maskarinec S, Warren B, Chu VH, Fortes CQ, Giannitsioti E, ... ... Otto M, et al. Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus. The Journal of Infection. PMID 26778460 DOI: 10.1016/J.Jinf.2015.11.002 |
0.501 |
|
| 2016 |
Bonesso MF, Yeh AJ, Villaruz AE, Joo HS, McCausland J, Fortaleza CM, Cavalcante RS, Sobrinho MT, Ronchi CF, Cheung GY, Cunha ML, Otto M. Key Role of α-Toxin in Fatal Pneumonia Caused by Staphylococcus aureus Sequence Type 398. American Journal of Respiratory and Critical Care Medicine. 193: 217-20. PMID 26771417 DOI: 10.1164/Rccm.201506-1225Le |
0.376 |
|
| 2015 |
Li T, He L, Song Y, Villaruz AE, Joo HS, Liu Q, Zhu Y, Wang Y, Qin J, Otto M, Li M. AraC-type regulator Rsp adapts Staphylococcus aureus gene expression to acute infection. Infection and Immunity. PMID 26712209 DOI: 10.1128/Iai.01088-15 |
0.508 |
|
| 2015 |
Vural A, Al-Khodor S, Cheung GY, Shi CS, Srinivasan L, McQuiston TJ, Hwang IY, Yeh AJ, Blumer JB, Briken V, Williamson PR, Otto M, Fraser ID, Kehrl JH. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26667172 DOI: 10.4049/Jimmunol.1501595 |
0.377 |
|
| 2015 |
Cheung GY, Yeh AJ, Kretschmer D, Duong AC, Tuffuor K, Fu CL, Joo HS, Diep BA, Li M, Nakamura Y, Nunez G, Peschel A, Otto M. Functional characteristics of the Staphylococcus aureus δ-toxin allelic variant G10S. Scientific Reports. 5: 18023. PMID 26658455 DOI: 10.1038/Srep18023 |
0.442 |
|
| 2015 |
Manifold-Wheeler BC, Elmore BO, Triplett KD, Castleman MJ, Otto M, Hall PR. Serum Lipoproteins Are Critical for Pulmonary Innate Defense against Staphylococcus aureus Quorum Sensing. Journal of Immunology (Baltimore, Md. : 1950). PMID 26608923 DOI: 10.4049/Jimmunol.1501835 |
0.418 |
|
| 2015 |
Scharschmidt TC, Vasquez KS, Truong HA, Gearty SV, Pauli ML, Nosbaum A, Gratz IK, Otto M, Moon JJ, Liese J, Abbas AK, Fischbach MA, Rosenblum MD. A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes. Immunity. 43: 1011-1021. PMID 26588783 DOI: 10.1016/J.Immuni.2015.10.016 |
0.328 |
|
| 2015 |
Dastgheyb SS, Otto M. Staphylococcal adaptation to diverse physiologic niches: an overview of transcriptomic and phenotypic changes in different biological environments. Future Microbiology. PMID 26584249 DOI: 10.2217/Fmb.15.116 |
0.375 |
|
| 2015 |
Le KY, Otto M. Quorum-sensing regulation in staphylococci-an overview. Frontiers in Microbiology. 6: 1174. PMID 26579084 DOI: 10.3389/Fmicb.2015.01174 |
0.492 |
|
| 2015 |
Vuong C, Yeh AJ, Cheung GY, Otto M. Investigational drugs to treat methicillin-resistant Staphylococcus aureus. Expert Opinion On Investigational Drugs. 1-21. PMID 26536498 DOI: 10.1517/13543784.2016.1109077 |
0.518 |
|
| 2015 |
Berlon NR, Qi R, Sharma-Kuinkel BK, Joo HS, Park LP, George D, Thaden JT, Messina JA, Maskarinec SA, Mueller-Premru M, Athan E, Tattevin P, Pericas JM, Woods CW, Otto M, et al. Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins. The Journal of Infection. PMID 26079275 DOI: 10.1016/J.Jinf.2015.06.005 |
0.396 |
|
| 2015 |
Dastgheyb SS, Villaruz AE, Le KY, Tan VY, Duong AC, Chatterjee SS, Cheung GY, Joo HS, Hickok NJ, Otto M. Role of Phenol-Soluble Modulins in Formation of Staphylococcus aureus Biofilms in Synovial Fluid. Infection and Immunity. 83: 2966-75. PMID 25964472 DOI: 10.1128/Iai.00394-15 |
0.502 |
|
| 2015 |
Kamenyeva O, Boularan C, Kabat J, Cheung GY, Cicala C, Yeh AJ, Chan JL, Periasamy S, Otto M, Kehrl JH. Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus. Plos Pathogens. 11: e1004827. PMID 25884622 DOI: 10.1371/Journal.Ppat.1004827 |
0.303 |
|
| 2015 |
Liu Q, Du X, Hong X, Li T, Zheng B, He L, Wang Y, Otto M, Li M. Targeting surface protein SasX by active and passive vaccination to reduce Staphylococcus aureus colonization and infection. Infection and Immunity. 83: 2168-74. PMID 25776748 DOI: 10.1128/Iai.02951-14 |
0.468 |
|
| 2015 |
Dastgheyb S, Hickok NJ, Otto M. Reply to Perez and Patel. The Journal of Infectious Diseases. 212: 336-7. PMID 25712972 DOI: 10.1093/Infdis/Jiv097 |
0.453 |
|
| 2015 |
Khan BA, Yeh AJ, Cheung GY, Otto M. Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections. Expert Opinion On Investigational Drugs. 24: 689-704. PMID 25704585 DOI: 10.1517/13543784.2015.1019062 |
0.437 |
|
| 2015 |
Joo HS, Otto M. Mechanisms of resistance to antimicrobial peptides in staphylococci. Biochimica Et Biophysica Acta. PMID 25701233 DOI: 10.1016/J.Bbamem.2015.02.009 |
0.485 |
|
| 2015 |
Deplanche M, Filho RA, Alekseeva L, Ladier E, Jardin J, Henry G, Azevedo V, Miyoshi A, Beraud L, Laurent F, Lina G, Vandenesch F, Steghens JP, Le Loir Y, Otto M, et al. Phenol-soluble modulin α induces G2/M phase transition delay in eukaryotic HeLa cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1950-9. PMID 25648996 DOI: 10.1096/Fj.14-260513 |
0.383 |
|
| 2015 |
Dastgheyb SS, Hammoud S, Ketonis C, Liu AY, Fitzgerald K, Parvizi J, Purtill J, Ciccotti M, Shapiro IM, Otto M, Hickok NJ. Staphylococcal persistence due to biofilm formation in synovial fluid containing prophylactic cefazolin. Antimicrobial Agents and Chemotherapy. 59: 2122-8. PMID 25624333 DOI: 10.1128/Aac.04579-14 |
0.441 |
|
| 2015 |
Cheung GY, Otto M. Microbiology: Diverted on the way to memory. Nature. 517: 28-9. PMID 25487148 DOI: 10.1038/Nature14083 |
0.337 |
|
| 2015 |
Dastgheyb S, Parvizi J, Shapiro IM, Hickok NJ, Otto M. Effect of biofilms on recalcitrance of staphylococcal joint infection to antibiotic treatment. The Journal of Infectious Diseases. 211: 641-50. PMID 25214518 DOI: 10.1093/Infdis/Jiu514 |
0.484 |
|
| 2015 |
Chen Y, Yeh AJ, Cheung GY, Villaruz AE, Tan VY, Joo HS, Chatterjee SS, Yu Y, Otto M. Basis of virulence in a Panton-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain. The Journal of Infectious Diseases. 211: 472-80. PMID 25139021 DOI: 10.1093/Infdis/Jiu462 |
0.487 |
|
| 2015 |
Millar E, Schlett C, Cui T, Tribble D, Hall E, Lanier J, Nagy L, Ellis M, Joo H, Fu C, Otto M, Bishop D. Do Serum Antibodies to Staphylococcus Aureus Psmα3 Protect Against Skin and Soft-Tissue Infection? Evidence From a Case-Control Study Among Military Trainees at High Risk for Disease Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.586 |
0.36 |
|
| 2015 |
Cheung GYC, Villaruz AE, Joo HS, Duong AC, Yeh AJ, Nguyen TH, Sturdevant DE, Queck SY, Otto M. Corrigendum to "Genome-wide analysis of the regulatory function mediated by the small regulatory psm-mec RNA of methicillin-resistant Staphylococcus aureus" [Int. J. Med. Microbiol. 304, (2014), 637-644] International Journal of Medical Microbiology. 305: 491. DOI: 10.1016/J.Ijmm.2015.03.006 |
0.353 |
|
| 2014 |
Le KY, Dastgheyb S, Ho TV, Otto M. Molecular determinants of staphylococcal biofilm dispersal and structuring. Frontiers in Cellular and Infection Microbiology. 4: 167. PMID 25505739 DOI: 10.3389/Fcimb.2014.00167 |
0.442 |
|
| 2014 |
Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, et al. Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus. Science (New York, N.Y.). 346: 641-6. PMID 25359976 DOI: 10.1126/Science.1258705 |
0.322 |
|
| 2014 |
Otto M. Physical stress and bacterial colonization. Fems Microbiology Reviews. 38: 1250-70. PMID 25212723 DOI: 10.1111/1574-6976.12088 |
0.367 |
|
| 2014 |
Cheung GY, Kretschmer D, Duong AC, Yeh AJ, Ho TV, Chen Y, Joo HS, Kreiswirth BN, Peschel A, Otto M. Production of an attenuated phenol-soluble modulin variant unique to the MRSA clonal complex 30 increases severity of bloodstream infection. Plos Pathogens. 10: e1004298. PMID 25144687 DOI: 10.1371/Journal.Ppat.1004298 |
0.561 |
|
| 2014 |
Sully EK, Malachowa N, Elmore BO, Alexander SM, Femling JK, Gray BM, DeLeo FR, Otto M, Cheung AL, Edwards BS, Sklar LA, Horswill AR, Hall PR, Gresham HD. Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. Plos Pathogens. 10: e1004174. PMID 24945495 DOI: 10.1371/Journal.Ppat.1004174 |
0.686 |
|
| 2014 |
Cheung GY, Villaruz AE, Joo HS, Duong AC, Yeh AJ, Nguyen TH, Sturdevant DE, Queck SY, Otto M. Genome-wide analysis of the regulatory function mediated by the small regulatory psm-mec RNA of methicillin-resistant Staphylococcus aureus. International Journal of Medical Microbiology : Ijmm. 304: 637-44. PMID 24877726 DOI: 10.1016/J.Ijmm.2014.04.008 |
0.436 |
|
| 2014 |
Berube BJ, Sampedro GR, Otto M, Bubeck Wardenburg J. The psmα locus regulates production of Staphylococcus aureus alpha-toxin during infection. Infection and Immunity. 82: 3350-8. PMID 24866799 DOI: 10.1128/Iai.00089-14 |
0.445 |
|
| 2014 |
Qu T, Feng Y, Jiang Y, Zhu P, Wei Z, Chen Y, Otto M, Yu Y. Whole genome analysis of a community-associated methicillin-resistant Staphylococcus aureus ST59 isolate from a case of human sepsis and severe pneumonia in China. Plos One. 9: e89235. PMID 24586619 DOI: 10.1371/Journal.Pone.0089235 |
0.459 |
|
| 2014 |
Otto M. Staphylococcus aureus toxins. Current Opinion in Microbiology. 17: 32-7. PMID 24581690 DOI: 10.1016/J.Mib.2013.11.004 |
0.49 |
|
| 2014 |
Stavrakis AI, Niska JA, Shahbazian JH, Loftin AH, Ramos RI, Billi F, Francis KP, Otto M, Bernthal NM, Uslan DZ, Miller LS. Combination prophylactic therapy with rifampin increases efficacy against an experimental Staphylococcus epidermidis subcutaneous implant-related infection. Antimicrobial Agents and Chemotherapy. 58: 2377-86. PMID 24514089 DOI: 10.1128/Aac.01943-13 |
0.368 |
|
| 2014 |
Yu D, Pi B, Chen Y, Wang Y, Ruan Z, Otto M, Yu Y. Characterization of the staphylococcal cassette chromosome composite island of Staphylococcus haemolyticus SH32, a methicillin-resistant clinical isolate from China. Plos One. 9: e87346. PMID 24466348 DOI: 10.1371/Journal.Pone.0087346 |
0.407 |
|
| 2014 |
Otto M. Phenol-soluble modulins. International Journal of Medical Microbiology : Ijmm. 304: 164-9. PMID 24447915 DOI: 10.1016/J.Ijmm.2013.11.019 |
0.546 |
|
| 2014 |
Cheung GY, Joo HS, Chatterjee SS, Otto M. Phenol-soluble modulins--critical determinants of staphylococcal virulence. Fems Microbiology Reviews. 38: 698-719. PMID 24372362 DOI: 10.1111/1574-6976.12057 |
0.486 |
|
| 2014 |
Rudkin JK, Laabei M, Edwards AM, Joo HS, Otto M, Lennon KL, O'Gara JP, Waterfield NR, Massey RC. Oxacillin alters the toxin expression profile of community-associated methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 58: 1100-7. PMID 24295979 DOI: 10.1128/Aac.01618-13 |
0.443 |
|
| 2014 |
Joo HS, Otto M. The isolation and analysis of phenol-soluble modulins of Staphylococcus epidermidis. Methods in Molecular Biology (Clifton, N.J.). 1106: 93-100. PMID 24222457 DOI: 10.1007/978-1-62703-736-5_7 |
0.41 |
|
| 2014 |
Otto M. Staphylococcus epidermidis pathogenesis. Methods in Molecular Biology (Clifton, N.J.). 1106: 17-31. PMID 24222452 DOI: 10.1007/978-1-62703-736-5_2 |
0.507 |
|
| 2014 |
Grosz M, Kolter J, Paprotka K, Winkler AC, Schäfer D, Chatterjee SS, Geiger T, Wolz C, Ohlsen K, Otto M, Rudel T, Sinha B, Fraunholz M. Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol-soluble modulin α. Cellular Microbiology. 16: 451-65. PMID 24164701 DOI: 10.1111/Cmi.12233 |
0.509 |
|
| 2014 |
Cheung GY, Kretschmer D, Queck SY, Joo HS, Wang R, Duong AC, Nguyen TH, Bach TH, Porter AR, DeLeo FR, Peschel A, Otto M. Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 153-61. PMID 24008753 DOI: 10.1096/Fj.13-232041 |
0.588 |
|
| 2014 |
Uhlemann AC, Otto M, Lowy FD, DeLeo FR. Evolution of community- and healthcare-associated methicillin-resistant Staphylococcus aureus. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 21: 563-74. PMID 23648426 DOI: 10.1016/J.Meegid.2013.04.030 |
0.697 |
|
| 2013 |
Otto M. How colonization factors are linked to outbreaks of methicillin-resistant Staphylococcus aureus: the roles of SasX and ACME. Biomolecular Concepts. 4: 533-7. PMID 25436596 DOI: 10.1515/Bmc-2013-0025 |
0.508 |
|
| 2013 |
Grinholc M, Nakonieczna J, Negri A, Rapacka-Zdonczyk A, Motyka A, Fila G, Kurlenda J, Leibner-Ciszak J, Otto M, Bielawski KP. The agr function and polymorphism: impact on Staphylococcus aureus susceptibility to photoinactivation. Journal of Photochemistry and Photobiology. B, Biology. 129: 100-7. PMID 24211295 DOI: 10.1016/J.Jphotobiol.2013.10.006 |
0.498 |
|
| 2013 |
Nakamura Y, Oscherwitz J, Cease KB, Chan SM, Muñoz-Planillo R, Hasegawa M, Villaruz AE, Cheung GY, McGavin MJ, Travers JB, Otto M, Inohara N, Núñez G. Staphylococcus δ-toxin induces allergic skin disease by activating mast cells. Nature. 503: 397-401. PMID 24172897 DOI: 10.1038/Nature12655 |
0.377 |
|
| 2013 |
Kobayashi SD, Olsen RJ, LaCasse RA, Safronetz D, Ashraf M, Porter AR, Braughton KR, Feldmann F, Clifton DR, Kash JC, Bailey JR, Gardner DJ, Otto M, Brining DL, Kreiswirth BN, et al. Seasonal H3N2 influenza A virus fails to enhance Staphylococcus aureus co-infection in a non-human primate respiratory tract infection model. Virulence. 4: 707-15. PMID 24104465 DOI: 10.4161/Viru.26572 |
0.648 |
|
| 2013 |
Peschel A, Otto M. Phenol-soluble modulins and staphylococcal infection. Nature Reviews. Microbiology. 11: 667-73. PMID 24018382 DOI: 10.1038/Nrmicro3110 |
0.495 |
|
| 2013 |
Chen Y, Chatterjee SS, Porcella SF, Yu YS, Otto M. Complete genome sequence of a Pantón-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain of sequence type 72 from Korea. Plos One. 8: e72803. PMID 23977354 DOI: 10.1371/Journal.Pone.0072803 |
0.429 |
|
| 2013 |
Chen J, Feng G, Guo Q, Wardenburg JB, Lin S, Inoshima I, Deaton R, Yuan JX, Garcia JG, Machado RF, Otto M, Wunderink RG. Transcriptional events during the recovery from MRSA lung infection: a mouse pneumonia model. Plos One. 8: e70176. PMID 23936388 DOI: 10.1371/Journal.Pone.0070176 |
0.371 |
|
| 2013 |
Chatterjee SS, Otto M. Improved understanding of factors driving methicillin-resistant Staphylococcus aureus epidemic waves. Clinical Epidemiology. 5: 205-17. PMID 23861600 DOI: 10.2147/Clep.S37071 |
0.521 |
|
| 2013 |
Chen J, Feng G, Song Y, Wardenburg JB, Lin S, Inoshima I, Otto M, Wunderink RG. Linezolid Exerts Greater Bacterial Clearance but No Modification of Host Lung Gene Expression Profiling: A Mouse MRSA Pneumonia Model. Plos One. 8: e67994. PMID 23826353 DOI: 10.1371/Journal.Pone.0067994 |
0.388 |
|
| 2013 |
Chatterjee SS, Otto M. How can Staphylococcus aureus phenol-soluble modulins be targeted to inhibit infection? Future Microbiology. 8: 693-6. PMID 23701324 DOI: 10.2217/Fmb.13.37 |
0.429 |
|
| 2013 |
Otto M. Blocking the spread of resistance. Science Translational Medicine. 5: 184fs17. PMID 23658243 DOI: 10.1126/Scitranslmed.3006128 |
0.401 |
|
| 2013 |
Otto M. Community-associated MRSA: what makes them special? International Journal of Medical Microbiology : Ijmm. 303: 324-30. PMID 23517691 DOI: 10.1016/J.Ijmm.2013.02.007 |
0.485 |
|
| 2013 |
Otto MP, Martin E, Badiou C, Lebrun S, Bes M, Vandenesch F, Etienne J, Lina G, Dumitrescu O. Effects of subinhibitory concentrations of antibiotics on virulence factor expression by community-acquired methicillin-resistant Staphylococcus aureus. The Journal of Antimicrobial Chemotherapy. 68: 1524-32. PMID 23508621 DOI: 10.1093/jac/dkt073 |
0.31 |
|
| 2013 |
Surewaard BG, de Haas CJ, Vervoort F, Rigby KM, DeLeo FR, Otto M, van Strijp JA, Nijland R. Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis. Cellular Microbiology. 15: 1427-37. PMID 23470014 DOI: 10.1111/Cmi.12130 |
0.679 |
|
| 2013 |
Schreiner J, Kretschmer D, Klenk J, Otto M, Bühring HJ, Stevanovic S, Wang JM, Beer-Hammer S, Peschel A, Autenrieth SE. Staphylococcus aureus phenol-soluble modulin peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 3417-26. PMID 23460735 DOI: 10.4049/Jimmunol.1202563 |
0.337 |
|
| 2013 |
Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. Plos Pathogens. 9: e1003166. PMID 23459693 DOI: 10.1371/Journal.Ppat.1003166 |
0.42 |
|
| 2013 |
Chatterjee SS, Joo HS, Duong AC, Dieringer TD, Tan VY, Song Y, Fischer ER, Cheung GY, Li M, Otto M. Essential Staphylococcus aureus toxin export system. Nature Medicine. 19: 364-7. PMID 23396209 DOI: 10.1038/Nm.3047 |
0.512 |
|
| 2013 |
Otto M. Coagulase-negative staphylococci as reservoirs of genes facilitating MRSA infection: Staphylococcal commensal species such as Staphylococcus epidermidis are being recognized as important sources of genes promoting MRSA colonization and virulence. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 4-11. PMID 23165978 DOI: 10.1002/Bies.201200112 |
0.546 |
|
| 2013 |
Otto M. Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity. Annual Review of Medicine. 64: 175-88. PMID 22906361 DOI: 10.1146/Annurev-Med-042711-140023 |
0.492 |
|
| 2012 |
Duong AC, Cheung GY, Otto M. Interaction of phenol-soluble modulins with phosphatidylcholine vesicles. Pathogens (Basel, Switzerland). 1: 3-11. PMID 25436601 DOI: 10.3390/Pathogens1010003 |
0.32 |
|
| 2012 |
Joo HS, Otto M. Molecular basis of in vivo biofilm formation by bacterial pathogens. Chemistry & Biology. 19: 1503-13. PMID 23261595 DOI: 10.1016/J.Chembiol.2012.10.022 |
0.476 |
|
| 2012 |
Otto M. Molecular insight into how MRSA is becoming increasingly dangerous. Virulence. 3: 521-3. PMID 23076285 DOI: 10.4161/Viru.21523 |
0.479 |
|
| 2012 |
Kronforst KD, Mancuso CJ, Pettengill M, Ninkovic J, Power Coombs MR, Stevens C, Otto M, Mallard C, Wang X, Goldmann D, Levy O. A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses. Plos One. 7: e43897. PMID 22970147 DOI: 10.1371/Journal.Pone.0043897 |
0.403 |
|
| 2012 |
Christner M, Heinze C, Busch M, Franke G, Hentschke M, Bayard Dühring S, Büttner H, Kotasinska M, Wischnewski V, Kroll G, Buck F, Molin S, Otto M, Rohde H. sarA negatively regulates Staphylococcus epidermidis biofilm formation by modulating expression of 1 MDa extracellular matrix binding protein and autolysis-dependent release of eDNA. Molecular Microbiology. 86: 394-410. PMID 22957858 DOI: 10.1111/J.1365-2958.2012.08203.X |
0.431 |
|
| 2012 |
Periasamy S, Chatterjee SS, Cheung GY, Otto M. Phenol-soluble modulins in staphylococci: What are they originally for? Communicative & Integrative Biology. 5: 275-7. PMID 22896791 DOI: 10.4161/Cib.19420 |
0.428 |
|
| 2012 |
Conlan S, Mijares LA, Becker J, Blakesley RW, Bouffard GG, Brooks S, Coleman H, Gupta J, Gurson N, Park M, Schmidt B, Thomas PJ, Otto M, Kong HH, et al. Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates. Genome Biology. 13: R64. PMID 22830599 DOI: 10.1186/Gb-2012-13-7-R64 |
0.394 |
|
| 2012 |
Bloes DA, Otto M, Peschel A, Kretschmer D. Enterococcus faecium stimulates human neutrophils via the formyl-peptide receptor 2. Plos One. 7: e39910. PMID 22768166 DOI: 10.1371/Journal.Pone.0039910 |
0.464 |
|
| 2012 |
Otto M. MRSA virulence and spread. Cellular Microbiology. 14: 1513-21. PMID 22747834 DOI: 10.1111/J.1462-5822.2012.01832.X |
0.499 |
|
| 2012 |
Cheung GY, Otto M. The potential use of toxin antibodies as a strategy for controlling acute Staphylococcus aureus infections. Expert Opinion On Therapeutic Targets. 16: 601-12. PMID 22530584 DOI: 10.1517/14728222.2012.682573 |
0.506 |
|
| 2012 |
Li M, Du X, Villaruz AE, Diep BA, Wang D, Song Y, Tian Y, Hu J, Yu F, Lu Y, Otto M. MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nature Medicine. 18: 816-9. PMID 22522561 DOI: 10.1038/Nm.2692 |
0.471 |
|
| 2012 |
Otto M. How Staphylococcus aureus breaches our skin to cause infection. The Journal of Infectious Diseases. 205: 1483-5. PMID 22457276 DOI: 10.1093/Infdis/Jis248 |
0.45 |
|
| 2012 |
Otto M. Methicillin-resistant Staphylococcus aureus infection is associated with increased mortality. Future Microbiology. 7: 189-91. PMID 22324988 DOI: 10.2217/Fmb.11.156 |
0.482 |
|
| 2012 |
Periasamy S, Joo HS, Duong AC, Bach TH, Tan VY, Chatterjee SS, Cheung GY, Otto M. How Staphylococcus aureus biofilms develop their characteristic structure. Proceedings of the National Academy of Sciences of the United States of America. 109: 1281-6. PMID 22232686 DOI: 10.1073/Pnas.1115006109 |
0.442 |
|
| 2012 |
Cheung GY, Duong AC, Otto M. Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis. Microbes and Infection / Institut Pasteur. 14: 380-6. PMID 22178792 DOI: 10.1016/J.Micinf.2011.11.013 |
0.459 |
|
| 2012 |
Otto M. Molecular basis of Staphylococcus epidermidis infections. Seminars in Immunopathology. 34: 201-14. PMID 22095240 DOI: 10.1007/S00281-011-0296-2 |
0.514 |
|
| 2012 |
Kretschmer D, Nikola N, Dürr M, Otto M, Peschel A. The virulence regulator Agr controls the staphylococcal capacity to activate human neutrophils via the formyl peptide receptor 2. Journal of Innate Immunity. 4: 201-12. PMID 22067547 DOI: 10.1159/000332142 |
0.425 |
|
| 2011 |
Chatterjee SS, Chen L, Joo HS, Cheung GY, Kreiswirth BN, Otto M. Distribution and regulation of the mobile genetic element-encoded phenol-soluble modulin PSM-mec in methicillin-resistant Staphylococcus aureus. Plos One. 6: e28781. PMID 22174895 DOI: 10.1371/Journal.Pone.0028781 |
0.473 |
|
| 2011 |
DeLeo FR, Kennedy AD, Chen L, Bubeck Wardenburg J, Kobayashi SD, Mathema B, Braughton KR, Whitney AR, Villaruz AE, Martens CA, Porcella SF, McGavin MJ, Otto M, Musser JM, Kreiswirth BN. Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 108: 18091-6. PMID 22025717 DOI: 10.1073/Pnas.1111084108 |
0.672 |
|
| 2011 |
Liu Q, Fan J, Niu C, Wang D, Wang J, Wang X, Villaruz AE, Li M, Otto M, Gao Q. The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis. Plos One. 6: e25380. PMID 21966513 DOI: 10.1371/Journal.Pone.0025380 |
0.315 |
|
| 2011 |
Gérôme P, Bourilhon N, Soullie B, Foucher B, Otto MP, Milou F. [Acute appendicitis due to both Klebsiella pneumoniae and serotype 35B Streptococcus pneumoniae, an emergent serotype]. Annales De Biologie Clinique. 69: 485-8. PMID 21896418 DOI: 10.1684/abc.2011.0594 |
0.309 |
|
| 2011 |
Kobayashi SD, Malachowa N, Whitney AR, Braughton KR, Gardner DJ, Long D, Bubeck Wardenburg J, Schneewind O, Otto M, Deleo FR. Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. The Journal of Infectious Diseases. 204: 937-41. PMID 21849291 DOI: 10.1093/Infdis/Jir441 |
0.668 |
|
| 2011 |
Malachowa N, Whitney AR, Kobayashi SD, Sturdevant DE, Kennedy AD, Braughton KR, Shabb DW, Diep BA, Chambers HF, Otto M, DeLeo FR. Global changes in Staphylococcus aureus gene expression in human blood. Plos One. 6: e18617. PMID 21525981 DOI: 10.1371/Journal.Pone.0018617 |
0.65 |
|
| 2011 |
Rosenthal ME, Dever LL, Moucha CS, Chavda KD, Otto M, Kreiswirth BN. Molecular characterization of an early invasive Staphylococcus epidermidis prosthetic joint infection. Microbial Drug Resistance (Larchmont, N.Y.). 17: 345-50. PMID 21510745 DOI: 10.1089/Mdr.2010.0157 |
0.49 |
|
| 2011 |
Otto M. Panton-Valentine leukocidin antibodies for the treatment of MRSA skin infections? Expert Review of Anti-Infective Therapy. 9: 389-92. PMID 21504395 DOI: 10.1586/Eri.11.19 |
0.478 |
|
| 2011 |
Zielinska AK, Beenken KE, Joo HS, Mrak LN, Griffin LM, Luong TT, Lee CY, Otto M, Shaw LN, Smeltzer MS. Defining the strain-dependent impact of the Staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of Staphylococcus aureus. Journal of Bacteriology. 193: 2948-58. PMID 21478342 DOI: 10.1128/Jb.01517-10 |
0.33 |
|
| 2011 |
Cheung GY, Wang R, Khan BA, Sturdevant DE, Otto M. Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infection and Immunity. 79: 1927-35. PMID 21402769 DOI: 10.1128/Iai.00046-11 |
0.472 |
|
| 2011 |
Otto M. A MRSA-terious enemy among us: end of the PVL controversy? Nature Medicine. 17: 169-70. PMID 21297612 DOI: 10.1038/Nm0211-169 |
0.371 |
|
| 2011 |
Joo HS, Cheung GY, Otto M. Antimicrobial activity of community-associated methicillin-resistant Staphylococcus aureus is caused by phenol-soluble modulin derivatives. The Journal of Biological Chemistry. 286: 8933-40. PMID 21278255 DOI: 10.1074/Jbc.M111.221382 |
0.531 |
|
| 2011 |
Rautenberg M, Joo HS, Otto M, Peschel A. Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1254-63. PMID 21183593 DOI: 10.1096/Fj.10-175208 |
0.431 |
|
| 2011 |
Wang X, Niu C, Sun G, Dong D, Villaruz AE, Li M, Wang D, Wang J, Otto M, Gao Q. ygs is a novel gene that influences biofilm formation and the general stress response of Staphylococcus epidermidis. Infection and Immunity. 79: 1007-15. PMID 21173311 DOI: 10.1128/Iai.00916-10 |
0.448 |
|
| 2011 |
Wang R, Khan BA, Cheung GY, Bach TH, Jameson-Lee M, Kong KF, Queck SY, Otto M. Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. The Journal of Clinical Investigation. 121: 238-48. PMID 21135501 DOI: 10.1172/Jci42520 |
0.487 |
|
| 2010 |
Otto M. Staphylococcus aureus toxin gene hitchhikes on a transferable antibiotic resistance element. Virulence. 1: 49-51. PMID 21178414 DOI: 10.4161/Viru.1.1.10453 |
0.458 |
|
| 2010 |
Li M, Cheung GY, Hu J, Wang D, Joo HS, Deleo FR, Otto M. Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains. The Journal of Infectious Diseases. 202: 1866-76. PMID 21050125 DOI: 10.1086/657419 |
0.682 |
|
| 2010 |
Cheung GY, Rigby K, Wang R, Queck SY, Braughton KR, Whitney AR, Teintze M, DeLeo FR, Otto M. Staphylococcus epidermidis strategies to avoid killing by human neutrophils. Plos Pathogens. 6: e1001133. PMID 20949069 DOI: 10.1371/Journal.Ppat.1001133 |
0.662 |
|
| 2010 |
Otto M. Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus. Annual Review of Microbiology. 64: 143-62. PMID 20825344 DOI: 10.1146/Annurev.Micro.112408.134309 |
0.496 |
|
| 2010 |
Joo HS, Chan JL, Cheung GY, Otto M. Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 54: 4942-4. PMID 20713669 DOI: 10.1128/Aac.00064-10 |
0.472 |
|
| 2010 |
Gordon O, Vig Slenters T, Brunetto PS, Villaruz AE, Sturdevant DE, Otto M, Landmann R, Fromm KM. Silver coordination polymers for prevention of implant infection: thiol interaction, impact on respiratory chain enzymes, and hydroxyl radical induction. Antimicrobial Agents and Chemotherapy. 54: 4208-18. PMID 20660682 DOI: 10.1128/Aac.01830-09 |
0.374 |
|
| 2010 |
Kretschmer D, Gleske AK, Rautenberg M, Wang R, Köberle M, Bohn E, Schöneberg T, Rabiet MJ, Boulay F, Klebanoff SJ, van Kessel KA, van Strijp JA, Otto M, Peschel A. Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus. Cell Host & Microbe. 7: 463-73. PMID 20542250 DOI: 10.1016/J.Chom.2010.05.012 |
0.493 |
|
| 2010 |
Otto M. Novel targeted immunotherapy approaches for staphylococcal infection. Expert Opinion On Biological Therapy. 10: 1049-59. PMID 20528609 DOI: 10.1517/14712598.2010.495115 |
0.538 |
|
| 2010 |
Strunk T, Power Coombs MR, Currie AJ, Richmond P, Golenbock DT, Stoler-Barak L, Gallington LC, Otto M, Burgner D, Levy O. TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia. Plos One. 5: e10111. PMID 20404927 DOI: 10.1371/Journal.Pone.0010111 |
0.336 |
|
| 2010 |
Wang C, Fan J, Niu C, Wang C, Villaruz AE, Otto M, Gao Q. Role of spx in biofilm formation of Staphylococcus epidermidis. Fems Immunology and Medical Microbiology. 59: 152-60. PMID 20402773 DOI: 10.1111/J.1574-695X.2010.00673.X |
0.45 |
|
| 2010 |
DeLeo FR, Otto M, Kreiswirth BN, Chambers HF. Community-associated meticillin-resistant Staphylococcus aureus. Lancet. 375: 1557-68. PMID 20206987 DOI: 10.1016/S0140-6736(09)61999-1 |
0.655 |
|
| 2010 |
Xia G, Maier L, Sanchez-Carballo P, Li M, Otto M, Holst O, Peschel A. Glycosylation of wall teichoic acid in Staphylococcus aureus by TarM. The Journal of Biological Chemistry. 285: 13405-15. PMID 20185825 DOI: 10.1074/Jbc.M109.096172 |
0.478 |
|
| 2010 |
Cheung GY, Otto M. Understanding the significance of Staphylococcus epidermidis bacteremia in babies and children. Current Opinion in Infectious Diseases. 23: 208-16. PMID 20179594 DOI: 10.1097/Qco.0B013E328337Fecb |
0.362 |
|
| 2010 |
Graves SF, Kobayashi SD, Braughton KR, Diep BA, Chambers HF, Otto M, Deleo FR. Relative contribution of Panton-Valentine leukocidin to PMN plasma membrane permeability and lysis caused by USA300 and USA400 culture supernatants. Microbes and Infection / Institut Pasteur. 12: 446-56. PMID 20172045 DOI: 10.1016/J.Micinf.2010.02.005 |
0.626 |
|
| 2010 |
Cogen AL, Yamasaki K, Sanchez KM, Dorschner RA, Lai Y, MacLeod DT, Torpey JW, Otto M, Nizet V, Kim JE, Gallo RL. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. The Journal of Investigative Dermatology. 130: 192-200. PMID 19710683 DOI: 10.1038/Jid.2009.243 |
0.415 |
|
| 2010 |
Otto M. Looking toward basic science for potential drug discovery targets against community-associated MRSA. Medicinal Research Reviews. 30: 1-22. PMID 19399829 DOI: 10.1002/Med.20160 |
0.525 |
|
| 2010 |
Otto M, Wardenburg J, DeLeo F. Reply to Vandenesch et al The Journal of Infectious Diseases. 201: 969-970. DOI: 10.1086/651027 |
0.475 |
|
| 2010 |
Deleo FR, Otto M, Kreiswirth BN, Chambers HF. Authors' reply The Lancet. 376: 767. DOI: 10.1016/S0140-6736(10)61370-0 |
0.614 |
|
| 2009 |
Miragaia M, de Lencastre H, Perdreau-Remington F, Chambers HF, Higashi J, Sullam PM, Lin J, Wong KI, King KA, Otto M, Sensabaugh GF, Diep BA. Genetic diversity of arginine catabolic mobile element in Staphylococcus epidermidis. Plos One. 4: e7722. PMID 19893740 DOI: 10.1371/Journal.Pone.0007722 |
0.373 |
|
| 2009 |
Queck SY, Khan BA, Wang R, Bach TH, Kretschmer D, Chen L, Kreiswirth BN, Peschel A, Deleo FR, Otto M. Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. Plos Pathogens. 5: e1000533. PMID 19649313 DOI: 10.1371/Journal.Ppat.1000533 |
0.67 |
|
| 2009 |
Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. Plos One. 4: e6387. PMID 19633710 DOI: 10.1371/Journal.Pone.0006387 |
0.473 |
|
| 2009 |
Kuehl R, Al-Bataineh S, Gordon O, Luginbuehl R, Otto M, Textor M, Landmann R. Furanone at subinhibitory concentrations enhances staphylococcal biofilm formation by luxS repression. Antimicrobial Agents and Chemotherapy. 53: 4159-66. PMID 19620329 DOI: 10.1128/Aac.01704-08 |
0.399 |
|
| 2009 |
Otto M. Staphylococcus epidermidis--the 'accidental' pathogen. Nature Reviews. Microbiology. 7: 555-67. PMID 19609257 DOI: 10.1038/Nrmicro2182 |
0.521 |
|
| 2009 |
Villaruz AE, Bubeck Wardenburg J, Khan BA, Whitney AR, Sturdevant DE, Gardner DJ, DeLeo FR, Otto M. A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. The Journal of Infectious Diseases. 200: 724-34. PMID 19604047 DOI: 10.1086/604728 |
0.649 |
|
| 2009 |
Li M, Rigby K, Lai Y, Nair V, Peschel A, Schittek B, Otto M. Staphylococcus aureus mutant screen reveals interaction of the human antimicrobial peptide dermcidin with membrane phospholipids. Antimicrobial Agents and Chemotherapy. 53: 4200-10. PMID 19596877 DOI: 10.1128/Aac.00428-09 |
0.451 |
|
| 2009 |
Otto M. Bacterial sensing of antimicrobial peptides. Contributions to Microbiology. 16: 136-149. PMID 19494583 DOI: 10.1159/000219377 |
0.456 |
|
| 2009 |
Voyich JM, Vuong C, DeWald M, Nygaard TK, Kocianova S, Griffith S, Jones J, Iverson C, Sturdevant DE, Braughton KR, Whitney AR, Otto M, DeLeo FR. The SaeR/S gene regulatory system is essential for innate immune evasion by Staphylococcus aureus. The Journal of Infectious Diseases. 199: 1698-706. PMID 19374556 DOI: 10.1086/598967 |
0.659 |
|
| 2009 |
Li M, Diep BA, Villaruz AE, Braughton KR, Jiang X, DeLeo FR, Chambers HF, Lu Y, Otto M. Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 106: 5883-8. PMID 19293374 DOI: 10.1073/Pnas.0900743106 |
0.675 |
|
| 2009 |
Otto M. Understanding the epidemic of community-associated MRSA and finding a cure: are we asking the right questions? Expert Review of Anti-Infective Therapy. 7: 141-3. PMID 19254161 DOI: 10.1586/14787210.7.2.141 |
0.483 |
|
| 2009 |
DeLeo FR, Diep BA, Otto M. Host defense and pathogenesis in Staphylococcus aureus infections. Infectious Disease Clinics of North America. 23: 17-34. PMID 19135914 DOI: 10.1016/J.Idc.2008.10.003 |
0.699 |
|
| 2008 |
Peterson MM, Mack JL, Hall PR, Alsup AA, Alexander SM, Sully EK, Sawires YS, Cheung AL, Otto M, Gresham HD. Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection. Cell Host & Microbe. 4: 555-66. PMID 19064256 DOI: 10.1016/J.Chom.2008.10.001 |
0.481 |
|
| 2008 |
Queck SY, Jameson-Lee M, Villaruz AE, Bach THL, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M. RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus. Molecular Cell. 32: 150-158. PMID 18851841 DOI: 10.1016/J.Molcel.2008.08.005 |
0.436 |
|
| 2008 |
Diep BA, Palazzolo-Ballance AM, Tattevin P, Basuino L, Braughton KR, Whitney AR, Chen L, Kreiswirth BN, Otto M, DeLeo FR, Chambers HF. Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Plos One. 3: e3198. PMID 18787708 DOI: 10.1371/Journal.Pone.0003198 |
0.667 |
|
| 2008 |
Bubeck Wardenburg J, Palazzolo-Ballance AM, Otto M, Schneewind O, DeLeo FR. Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. The Journal of Infectious Diseases. 198: 1166-70. PMID 18729780 DOI: 10.1086/592053 |
0.678 |
|
| 2008 |
Diep BA, Otto M. The role of virulence determinants in community-associated MRSA pathogenesis Trends in Microbiology. 16: 361-369. PMID 18585915 DOI: 10.1016/J.Tim.2008.05.002 |
0.42 |
|
| 2008 |
Ben Zakour NL, Sturdevant DE, Even S, Guinane CM, Barbey C, Alves PD, Cochet MF, Gautier M, Otto M, Fitzgerald JR, Le Loir Y. Genome-wide analysis of ruminant Staphylococcus aureus reveals diversification of the core genome. Journal of Bacteriology. 190: 6302-17. PMID 18567666 DOI: 10.1128/Jb.01984-07 |
0.381 |
|
| 2008 |
Vuong C, Kocianova S, Yu J, Kadurugamuwa JL, Otto M. Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection. The Journal of Infectious Diseases. 198: 258-61. PMID 18491976 DOI: 10.1086/589307 |
0.468 |
|
| 2008 |
Wang L, Li M, Dong D, Bach TH, Sturdevant DE, Vuong C, Otto M, Gao Q. SarZ is a key regulator of biofilm formation and virulence in Staphylococcus epidermidis. The Journal of Infectious Diseases. 197: 1254-62. PMID 18422437 DOI: 10.1086/586714 |
0.51 |
|
| 2008 |
Otto M, DeLeo FR. Methods molecular biology. Preface. Methods in Molecular Biology (Clifton, N.J.). 431: V-VI. PMID 18421842 |
0.421 |
|
| 2008 |
Vuong C, Otto M. The biofilm exopolysaccharide polysaccharide intercellular adhesin--a molecular and biochemical approach. Methods in Molecular Biology (Clifton, N.J.). 431: 97-106. PMID 18287750 DOI: 10.1007/978-1-60327-032-8_8 |
0.434 |
|
| 2008 |
DeLeo FR, Otto M. An antidote for Staphylococcus aureus pneumonia? The Journal of Experimental Medicine. 205: 271-4. PMID 18268043 DOI: 10.1084/Jem.20080167 |
0.697 |
|
| 2008 |
Kennedy AD, Otto M, Braughton KR, Whitney AR, Chen L, Mathema B, Mediavilla JR, Byrne KA, Parkins LD, Tenover FC, Kreiswirth BN, Musser JM, DeLeo FR. Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification. Proceedings of the National Academy of Sciences of the United States of America. 105: 1327-32. PMID 18216255 DOI: 10.1073/Pnas.0710217105 |
0.659 |
|
| 2008 |
Otto M. Targeted Immunotherapy for Staphylococcal Infections Biodrugs. 22: 27-36. PMID 18215088 DOI: 10.2165/00063030-200822010-00003 |
0.461 |
|
| 2008 |
Li M, Villaruz AE, Vadyvaloo V, Sturdevant DE, Otto M. AI-2-dependent gene regulation in Staphylococcus epidermidis. Bmc Microbiology. 8: 4. PMID 18182108 DOI: 10.1186/1471-2180-8-4 |
0.404 |
|
| 2008 |
Guinane CM, Sturdevant DE, Herron-Olson L, Otto M, Smyth DS, Villaruz AE, Kapur V, Hartigan PJ, Smyth CJ, Fitzgerald JR. Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health. The Journal of Infectious Diseases. 197: 205-13. PMID 18177250 DOI: 10.1086/524689 |
0.44 |
|
| 2008 |
Palazzolo-Ballance AM, Reniere ML, Braughton KR, Sturdevant DE, Otto M, Kreiswirth BN, Skaar EP, DeLeo FR. Neutrophil microbicides induce a pathogen survival response in community-associated methicillin-resistant Staphylococcus aureus. Journal of Immunology (Baltimore, Md. : 1950). 180: 500-9. PMID 18097052 DOI: 10.4049/Jimmunol.180.1.500 |
0.67 |
|
| 2008 |
Otto M. Antibodies to block Staph virulence. Chemistry & Biology. 14: 1093-4. PMID 17961820 DOI: 10.1016/J.Chembiol.2007.10.001 |
0.368 |
|
| 2008 |
DeLeo FR, Otto M. An antidote for Staphylococcus aureus pneumonia? Journal of Experimental Medicine. 205: 739-739. DOI: 10.1084/Jem.20080167021208C |
0.674 |
|
| 2007 |
Bubeck Wardenburg J, Bae T, Otto M, Deleo FR, Schneewind O. Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nature Medicine. 13: 1405-6. PMID 18064027 DOI: 10.1038/Nm1207-1405 |
0.582 |
|
| 2007 |
Wang R, Braughton KR, Kretschmer D, Bach TH, Queck SY, Li M, Kennedy AD, Dorward DW, Klebanoff SJ, Peschel A, DeLeo FR, Otto M. Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nature Medicine. 13: 1510-4. PMID 17994102 DOI: 10.1038/Nm1656 |
0.687 |
|
| 2007 |
Li M, Cha DJ, Lai Y, Villaruz AE, Sturdevant DE, Otto M. The antimicrobial peptide-sensing system aps of Staphylococcus aureus. Molecular Microbiology. 66: 1136-47. PMID 17961141 DOI: 10.1111/J.1365-2958.2007.05986.X |
0.527 |
|
| 2007 |
Otto M. Community-associated MRSA: a dangerous epidemic. Future Microbiology. 2: 457-9. PMID 17927464 DOI: 10.2217/17460913.2.5.457 |
0.525 |
|
| 2007 |
Wang C, Li M, Dong D, Wang J, Ren J, Otto M, Gao Q. Role of ClpP in biofilm formation and virulence of Staphylococcus epidermidis. Microbes and Infection. 9: 1376-83. PMID 17890122 DOI: 10.1016/J.Micinf.2007.06.012 |
0.468 |
|
| 2007 |
Klingenberg C, Rønnestad A, Anderson AS, Abrahamsen TG, Zorman J, Villaruz A, Flaegstad T, Otto M, Sollid JE. Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and invasiveness. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 13: 1100-11. PMID 17850346 DOI: 10.1111/J.1469-0691.2007.01818.X |
0.443 |
|
| 2007 |
Zhu Y, Weiss EC, Otto M, Fey PD, Smeltzer MS, Somerville GA. Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis. Infection and Immunity. 75: 4219-26. PMID 17576756 DOI: 10.1128/Iai.00509-07 |
0.433 |
|
| 2007 |
Montanaro L, Campoccia D, Pirini V, Ravaioli S, Otto M, Arciola CR. Antibiotic multiresistance strictly associated with IS256 and ica genes in Staphylococcus epidermidis strains from implant orthopedic infections. Journal of Biomedical Materials Research Part A. 83: 813-818. PMID 17559115 DOI: 10.1002/Jbm.A.31399 |
0.475 |
|
| 2007 |
Li M, Lai Y, Villaruz AE, Cha DJ, Sturdevant DE, Otto M. Gram-positive three-component antimicrobial peptide-sensing system. Proceedings of the National Academy of Sciences of the United States of America. 104: 9469-74. PMID 17517597 DOI: 10.1073/Pnas.0702159104 |
0.42 |
|
| 2007 |
Voyich JM, Otto M, Mathema B, Kreiswirth BN, DeLeo FR. Reply to Kernodle and to Schwartzman et al. [3] Journal of Infectious Diseases. 195: 1727-1728. DOI: 10.1086/517527 |
0.475 |
|
| 2006 |
Lai Y, Villaruz AE, Li M, Cha DJ, Sturdevant DE, Otto M. The human anionic antimicrobial peptide dermcidin induces proteolytic defence mechanisms in staphylococci. Molecular Microbiology. 63: 497-506. PMID 17176256 DOI: 10.1111/J.1365-2958.2006.05540.X |
0.484 |
|
| 2006 |
Voyich JM, Otto M, Mathema B, Braughton KR, Whitney AR, Welty D, Long RD, Dorward DW, Gardner DJ, Lina G, Kreiswirth BN, DeLeo FR. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? The Journal of Infectious Diseases. 194: 1761-70. PMID 17109350 DOI: 10.1086/509506 |
0.658 |
|
| 2006 |
Otto M. Bacterial evasion of antimicrobial peptides by biofilm formation. Current Topics in Microbiology and Immunology. 306: 251-8. PMID 16909925 DOI: 10.1007/3-540-29916-5_10 |
0.486 |
|
| 2006 |
Kong KF, Vuong C, Otto M. Staphylococcus quorum sensing in biofilm formation and infection. International Journal of Medical Microbiology : Ijmm. 296: 133-9. PMID 16487744 DOI: 10.1016/J.Ijmm.2006.01.042 |
0.495 |
|
| 2006 |
Yao Y, Vuong C, Kocianova S, Villaruz AE, Lai Y, Sturdevant DE, Otto M. Characterization of the Staphylococcus epidermidis accessory-gene regulator response: quorum-sensing regulation of resistance to human innate host defense. The Journal of Infectious Diseases. 193: 841-8. PMID 16479519 DOI: 10.1086/500246 |
0.467 |
|
| 2006 |
Dürr MC, Kristian SA, Otto M, Matteoli G, Margolis PS, Trias J, van Kessel KP, van Strijp JA, Bohn E, Landmann R, Peschel A. Neutrophil chemotaxis by pathogen-associated molecular patterns--formylated peptides are crucial but not the sole neutrophil attractants produced by Staphylococcus aureus. Cellular Microbiology. 8: 207-17. PMID 16441432 DOI: 10.1111/J.1462-5822.2005.00610.X |
0.494 |
|
| 2006 |
Xu L, Li H, Vuong C, Vadyvaloo V, Wang J, Yao Y, Otto M, Gao Q. Role of the luxS quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis. Infection and Immunity. 74: 488-96. PMID 16369005 DOI: 10.1128/Iai.74.1.488-496.2006 |
0.49 |
|
| 2006 |
Vadyvaloo V, Otto M. Molecular genetics of Staphylococcus epidermidis biofilms on indwelling medical devices. The International Journal of Artificial Organs. 28: 1069-78. PMID 16353113 DOI: 10.1177/039139880502801104 |
0.491 |
|
| 2005 |
Gu J, Li H, Li M, Vuong C, Otto M, Wen Y, Gao Q. Bacterial insertion sequence IS256 as a potential molecular marker to discriminate invasive strains from commensal strains of Staphylococcus epidermidis. Journal of Hospital Infection. 61: 342-348. PMID 16242209 DOI: 10.1016/J.Jhin.2005.04.017 |
0.436 |
|
| 2005 |
Li H, Xu L, Wang J, Wen Y, Vuong C, Otto M, Gao Q. Conversion of Staphylococcus epidermidis strains from commensal to invasive by expression of the ica locus encoding production of biofilm exopolysaccharide. Infection and Immunity. 73: 3188-91. PMID 15845531 DOI: 10.1128/Iai.73.5.3188-3191.2005 |
0.458 |
|
| 2005 |
Yao Y, Sturdevant DE, Villaruz A, Xu L, Gao Q, Otto M. Factors characterizing Staphylococcus epidermidis invasiveness determined by comparative genomics. Infection and Immunity. 73: 1856-60. PMID 15731088 DOI: 10.1128/Iai.73.3.1856-1860.2005 |
0.419 |
|
| 2005 |
Kocianova S, Vuong C, Yao Y, Voyich JM, Fischer ER, DeLeo FR, Otto M. Key role of poly-gamma-DL-glutamic acid in immune evasion and virulence of Staphylococcus epidermidis. The Journal of Clinical Investigation. 115: 688-94. PMID 15696197 DOI: 10.1172/Jci23523 |
0.691 |
|
| 2005 |
Yao Y, Sturdevant DE, Otto M. Genomewide analysis of gene expression in Staphylococcus epidermidis biofilms: insights into the pathophysiology of S. epidermidis biofilms and the role of phenol-soluble modulins in formation of biofilms. The Journal of Infectious Diseases. 191: 289-98. PMID 15609240 DOI: 10.1086/426945 |
0.498 |
|
| 2005 |
Otto M. Quorum-sensing control in Staphylococci -- a target for antimicrobial drug therapy? Fems Microbiology Letters. 241: 135-41. PMID 15598524 DOI: 10.1016/J.Femsle.2004.11.016 |
0.495 |
|
| 2004 |
Vuong C, Kocianova S, Voyich JM, Yao Y, Fischer ER, DeLeo FR, Otto M. A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence. The Journal of Biological Chemistry. 279: 54881-6. PMID 15501828 DOI: 10.1074/Jbc.M411374200 |
0.686 |
|
| 2004 |
Vuong C, Kocianova S, Yao Y, Carmody AB, Otto M. Increased colonization of indwelling medical devices by quorum-sensing mutants of Staphylococcus epidermidis in vivo. The Journal of Infectious Diseases. 190: 1498-505. PMID 15378444 DOI: 10.1086/424487 |
0.498 |
|
| 2004 |
Rothfork JM, Timmins GS, Harris MN, Chen X, Lusis AJ, Otto M, Cheung AL, Gresham HD. Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proceedings of the National Academy of Sciences of the United States of America. 101: 13867-72. PMID 15353593 DOI: 10.1073/Pnas.0402996101 |
0.453 |
|
| 2004 |
Otto M, O'Mahoney DS, Guina T, Klebanoff SJ. Activity of Staphylococcus epidermidis phenol-soluble modulin peptides expressed in Staphylococcus carnosus. The Journal of Infectious Diseases. 190: 748-55. PMID 15272403 DOI: 10.1086/422157 |
0.333 |
|
| 2004 |
Voyich JM, Braughton KR, Sturdevant DE, Vuong C, Kobayashi SD, Porcella SF, Otto M, Musser JM, DeLeo FR. Engagement of the pathogen survival response used by group A Streptococcus to avert destruction by innate host defense. Journal of Immunology (Baltimore, Md. : 1950). 173: 1194-201. PMID 15240710 DOI: 10.4049/Jimmunol.173.2.1194 |
0.647 |
|
| 2004 |
Vuong C, Dürr M, Carmody AB, Peschel A, Klebanoff SJ, Otto M. Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins. Cellular Microbiology. 6: 753-9. PMID 15236642 DOI: 10.1111/J.1462-5822.2004.00401.X |
0.463 |
|
| 2004 |
Otto M. Virulence factors of the coagulase-negative staphylococci. Frontiers in Bioscience : a Journal and Virtual Library. 9: 841-63. PMID 14766414 DOI: 10.2741/1295 |
0.477 |
|
| 2004 |
Vuong C, Voyich JM, Fischer ER, Braughton KR, Whitney AR, DeLeo FR, Otto M. Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system. Cellular Microbiology. 6: 269-75. PMID 14764110 DOI: 10.1046/J.1462-5822.2004.00367.X |
0.667 |
|
| 2004 |
Carmody AB, Otto M. Specificity grouping of the accessory gene regulator quorum-sensing system of Staphylococcus epidermidis is linked to infection Archives of Microbiology. 181: 250-253. PMID 14714104 DOI: 10.1007/S00203-003-0644-2 |
0.481 |
|
| 2003 |
Somerville GA, Cockayne A, Dürr M, Peschel A, Otto M, Musser JM. Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity. Journal of Bacteriology. 185: 6686-94. PMID 14594843 DOI: 10.1128/Jb.185.22.6686-6694.2003 |
0.348 |
|
| 2003 |
Vuong C, Gerke C, Somerville GA, Fischer ER, Otto M. Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. The Journal of Infectious Diseases. 188: 706-18. PMID 12934187 DOI: 10.1086/377239 |
0.464 |
|
| 2003 |
Kies S, Vuong C, Hille M, Peschel A, Meyer C, Götz F, Otto M. Control of antimicrobial peptide synthesis by the agr quorum sensing system in Staphylococcus epidermidis: activity of the lantibiotic epidermin is regulated at the level of precursor peptide processing. Peptides. 24: 329-38. PMID 12732329 DOI: 10.1016/S0196-9781(03)00046-9 |
0.411 |
|
| 2002 |
Vuong C, Otto M. Staphylococcus epidermidis infections. Microbes and Infection. 4: 481-9. PMID 11932199 DOI: 10.1016/S1286-4579(02)01563-0 |
0.518 |
|
| 2001 |
Kies S, Otto M, Vuong C, Götz F. Identification of the sigB operon in Staphylococcus epidermidis: construction and characterization of a sigB deletion mutant. Infection and Immunity. 69: 7933-6. PMID 11705980 DOI: 10.1128/Iai.69.12.7933-7936.2001 |
0.346 |
|
| 2001 |
Otto M. Staphylococcus aureus and Staphylococcus epidermidis peptide pheromones produced by the accessory gene regulator agr system. Peptides. 22: 1603-1608. PMID 11587788 DOI: 10.1016/S0196-9781(01)00495-8 |
0.374 |
|
| 2001 |
Otto M, Götz F. ABC transporters of staphylococci. Research in Microbiology. 152: 351-356. PMID 11421282 DOI: 10.1016/S0923-2508(01)01206-2 |
0.4 |
|
| 2001 |
Peschel A, Jack RW, Otto M, Collins LV, Staubitz P, Nicholson G, Kalbacher H, Nieuwenhuizen WF, Jung G, Tarkowski A, Kessel KPMv, Strijp JAGv. Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine Journal of Experimental Medicine. 193: 1067-1076. PMID 11342591 DOI: 10.1084/Jem.193.9.1067 |
0.504 |
|
| 2001 |
Otto M, Echner H, Voelter W, Götz F. Pheromone cross-inhibition between Staphylococcus aureus and Staphylococcus epidermidis. Infection and Immunity. 69: 1957-1960. PMID 11179383 DOI: 10.1128/Iai.69.3.1957-1960.2001 |
0.42 |
|
| 2000 |
Saenz HL, Augsburger V, Vuong C, Jack RW, Götz F, Otto M. Inducible expression and cellular location of AgrB, a protein involved in the maturation of the staphylococcal quorum-sensing pheromone. Archives of Microbiology. 174: 452-455. PMID 11195102 DOI: 10.1007/S002030000223 |
0.301 |
|
| 2000 |
Vuong C, Saenz HL, Götz F, Otto M. Impact of the agr Quorum-Sensing System on Adherence to Polystyrene in Staphylococcus aureus The Journal of Infectious Diseases. 182: 1688-1693. PMID 11069241 DOI: 10.1086/317606 |
0.501 |
|
| 2000 |
Peschel A, Vuong C, Otto M, Götz F. The d-Alanine Residues of Staphylococcus aureus Teichoic Acids Alter the Susceptibility to Vancomycin and the Activity of Autolytic Enzymes Antimicrobial Agents and Chemotherapy. 44: 2845-2847. PMID 10991869 DOI: 10.1128/Aac.44.10.2845-2847.2000 |
0.406 |
|
| 2000 |
Vuong C, Götz F, Otto M. Construction and characterization of an agr deletion mutant of Staphylococcus epidermidis. Infection and Immunity. 68: 1048-1053. PMID 10678906 DOI: 10.1128/Iai.68.3.1048-1053.2000 |
0.366 |
|
| 1999 |
Otto M, Süßmuth R, Vuong C, Jung G, Götz F. Inhibition of virulence factor expression in Staphylococcus aureus by the Staphylococcus epidermidis agr pheromone and derivatives. Febs Letters. 450: 257-262. PMID 10359085 DOI: 10.1016/S0014-5793(99)00514-1 |
0.461 |
|
| 1999 |
Peschel A, Otto M, Jack RW, Kalbacher H, Jung G, Götz F. Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. Journal of Biological Chemistry. 274: 8405-8410. PMID 10085071 DOI: 10.1074/Jbc.274.13.8405 |
0.42 |
|
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