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Bernard Roizman - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Virology
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Year Citation  Score
2020 Zhou X, Wang L, Zou W, Chen X, Roizman B, Zhou GG. hnRNPA2B1 associated with recruitment of RNA into exosomes plays a key role in HSV-1 release from infected cells. Journal of Virology. PMID 32295924 DOI: 10.1128/JVI.00367-20  0.503
2019 Huang R, Wu J, Zhou X, Jiang H, Zhou GG, Roizman B. HSV-1 miR-H28 exported to uninfected cells in exosomes restricts cell-to-cell virus spread by inducing IFNγ mRNAs. Journal of Virology. PMID 31413129 DOI: 10.1128/JVI.01005-19  0.349
2019 She M, Jiang H, Chen X, Chen X, Liu X, Zhang X, Roizman B, Zhou GG. GADD45γ activated early in the course of HSV-1 infection suppresses the activation of a network of innate immunity genes. Journal of Virology. PMID 30700604 DOI: 10.1128/JVI.02201-18  0.323
2019 Cassady K, Miller K, Prasad N, Maric D, Bernstock J, Roth J, Barker N, Coleman J, Schieffer K, Leraas K, Miller A, Leavenworth J, Cutter G, Whitley R, Roizman B, et al. ATIM-32. PREDICTORS OF IMPROVED SURVIVAL FOLLOWING ONCOLYTIC VIRUS TREATMENT IN PATIENTS WITH RECURRENT GLIOBLASTOMA: GENE EXPRESSION ANALYSIS FROM THE PHASE IB G207 CLINICAL TRIAL Neuro-Oncology. 21: vi8-vi8. DOI: 10.1093/Neuonc/Noz175.031  0.323
2018 Liu Y, Liu Y, Wu J, Roizman B, Zhou GG. Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29559532 DOI: 10.1073/pnas.1720464115  0.376
2017 Liu Y, Qu L, Liu Y, Roizman B, Zhou GG. PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760986 DOI: 10.1073/pnas.1708713114  0.33
2017 Xu P, Roizman B. The SP100 component of ND10 enhances accumulation of PML and suppresses replication and the assembly of HSV replication compartments. Proceedings of the National Academy of Sciences of the United States of America. PMID 28439026 DOI: 10.1073/pnas.1703395114  0.496
2016 Xu P, Mallon S, Roizman B. PML plays both inimical and beneficial roles in HSV-1 replication. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162364 DOI: 10.1073/Pnas.1605513113  0.803
2016 Han Z, Liu X, Chen X, Zhou X, Du T, Roizman B, Zhou G. miR-H28 and miR-H29 expressed late in productive infection are exported and restrict HSV-1 replication and spread in recipient cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831114 DOI: 10.1073/pnas.1525674113  0.393
2015 Shu M, Du T, Zhou G, Roizman B. Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia. Proceedings of the National Academy of Sciences of the United States of America. 112: E5420-6. PMID 26305977 DOI: 10.1073/pnas.1515369112  0.47
2015 Roizman B, Zhou G. The 3 facets of regulation of herpes simplex virus gene expression: A critical inquiry. Virology. 479: 562-7. PMID 25771487 DOI: 10.1016/j.virol.2015.02.036  0.52
2015 Shu M, Taddeo B, Roizman B. Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage. Journal of Virology. 89: 5643-50. PMID 25762736 DOI: 10.1128/JVI.00091-15  0.375
2015 Du T, Han Z, Zhou G, Roizman B. Patterns of accumulation of miRNAs encoded by herpes simplex virus during productive infection, latency, and on reactivation. Proceedings of the National Academy of Sciences of the United States of America. 112: E49-55. PMID 25535379 DOI: 10.1073/pnas.1422657112  0.373
2014 Kalamvoki M, Du T, Roizman B. Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 111: E4991-6. PMID 25368198 DOI: 10.1073/pnas.1419338111  0.509
2014 Zhu Z, Du T, Zhou G, Roizman B. The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase. Journal of Virology. 88: 5437-43. PMID 24574411 DOI: 10.1128/JVI.00542-14  0.533
2014 Kalamvoki M, Roizman B. HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation. Proceedings of the National Academy of Sciences of the United States of America. 111: E611-7. PMID 24449861 DOI: 10.1073/pnas.1323414111  0.54
2014 Widau RC, Parekh AD, Ranck MC, Golden DW, Kumar KA, Sood RF, Pitroda SP, Liao Z, Huang X, Darga TE, Xu D, Huang L, Andrade J, Roizman B, Weichselbaum RR, et al. RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation. Proceedings of the National Academy of Sciences of the United States of America. 111: E484-91. PMID 24434553 DOI: 10.1016/J.Ijrobp.2014.05.623  0.34
2013 Shu M, Taddeo B, Roizman B. The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs. Journal of Virology. 87: 13569-78. PMID 24109211 DOI: 10.1128/JVI.02603-13  0.406
2013 Roizman B, Whitley RJ. An inquiry into the molecular basis of HSV latency and reactivation. Annual Review of Microbiology. 67: 355-74. PMID 24024635 DOI: 10.1146/annurev-micro-092412-155654  0.451
2013 Gu H, Zheng Y, Roizman B. Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention. Journal of Virology. 87: 10244-54. PMID 23864622 DOI: 10.1128/Jvi.01487-13  0.454
2013 Du T, Zhou G, Roizman B. Modulation of reactivation of latent herpes simplex virus 1 in ganglionic organ cultures by p300/CBP and STAT3. Proceedings of the National Academy of Sciences of the United States of America. 110: E2621-8. PMID 23788661 DOI: 10.1073/pnas.1309906110  0.459
2013 Zhou G, Du T, Roizman B. The role of the CoREST/REST repressor complex in herpes simplex virus 1 productive infection and in latency. Viruses. 5: 1208-18. PMID 23628827 DOI: 10.3390/v5051208  0.396
2013 Shu M, Taddeo B, Zhang W, Roizman B. Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein. Proceedings of the National Academy of Sciences of the United States of America. 110: E1669-75. PMID 23589852 DOI: 10.1073/pnas.1305475110  0.436
2013 Taddeo B, Zhang W, Roizman B. The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection. Journal of Virology. 87: 4516-22. PMID 23388723 DOI: 10.1128/JVI.00005-13  0.45
2013 Zhou G, Du T, Roizman B. HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed. Proceedings of the National Academy of Sciences of the United States of America. 110: E498-506. PMID 23341636 DOI: 10.1073/pnas.1222497110  0.494
2013 Sciortino MT, Parisi T, Siracusano G, Mastino A, Taddeo B, Roizman B. The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1. Journal of Virology. 87: 3271-6. PMID 23302873 DOI: 10.1128/JVI.03049-12  0.548
2012 Mallon S, Wakim BT, Roizman B. Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression. Proceedings of the National Academy of Sciences of the United States of America. 109: E3549-57. PMID 23223531 DOI: 10.1073/Pnas.1218783109  0.804
2012 Kalamvoki M, Gu H, Roizman B. Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression. Journal of Virology. 86: 12871-8. PMID 22993145 DOI: 10.1128/Jvi.01981-12  0.532
2012 Du T, Zhou G, Roizman B. Induction of apoptosis accelerates reactivation of latent HSV-1 in ganglionic organ cultures and replication in cell cultures. Proceedings of the National Academy of Sciences of the United States of America. 109: 14616-21. PMID 22908263 DOI: 10.1073/pnas.1212661109  0.499
2012 Khodarev NN, Roizman B, Weichselbaum RR. Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3015-21. PMID 22615451 DOI: 10.1158/1078-0432.CCR-11-3225  0.303
2011 Du T, Zhou G, Roizman B. HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs. Proceedings of the National Academy of Sciences of the United States of America. 108: 18820-4. PMID 22065742 DOI: 10.1073/pnas.1117203108  0.417
2011 Roizman B, Zhou G, Du T. Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues. Journal of Neurovirology. 17: 512-7. PMID 22052379 DOI: 10.1007/s13365-011-0058-x  0.502
2011 Wang X, Patenode C, Roizman B. US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 108: 14632-6. PMID 21844356 DOI: 10.1073/pnas.1111942108  0.497
2011 Kalamvoki M, Roizman B. The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22. Journal of Virology. 85: 9472-7. PMID 21734043 DOI: 10.1128/JVI.00876-11  0.484
2011 Advani SJ, Markert JM, Sood RF, Samuel S, Gillespie GY, Shao MY, Roizman B, Weichselbaum RR. Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1. Gene Therapy. 18: 1098-102. PMID 21544094 DOI: 10.1038/Gt.2011.61  0.381
2011 Roizman B. The checkpoints of viral gene expression in productive and latent infection: the role of the HDAC/CoREST/LSD1/REST repressor complex. Journal of Virology. 85: 7474-82. PMID 21450817 DOI: 10.1128/JVI.00180-11  0.468
2011 Zhou G, Te D, Roizman B. The CoREST/REST repressor is both necessary and inimical for expression of herpes simplex virus genes. Mbio. 2: e00313-10. PMID 21221247 DOI: 10.1128/mBio.00313-10  0.428
2010 Kalamvoki M, Roizman B. Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression. Proceedings of the National Academy of Sciences of the United States of America. 107: 17721-6. PMID 20876123 DOI: 10.1073/pnas.1012991107  0.517
2010 Du T, Zhou G, Khan S, Gu H, Roizman B. Disruption of HDAC/CoREST/REST repressor by dnREST reduces genome silencing and increases virulence of herpes simplex virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 15904-9. PMID 20798038 DOI: 10.1073/Pnas.1010741107  0.517
2010 Kalamvoki M, Roizman B. Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes. Journal of Virology. 84: 9709-17. PMID 20660182 DOI: 10.1128/JVI.01050-10  0.48
2010 Taddeo B, Zhang W, Roizman B. Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase. Journal of Virology. 84: 10182-90. PMID 20631134 DOI: 10.1128/JVI.00975-10  0.542
2010 Jovasevic V, Roizman B. The novel HSV-1 US5-1 RNA is transcribed off a domain encoding US5, US4, US3, US2 and alpha22. Virology Journal. 7: 103. PMID 20492679 DOI: 10.1186/1743-422X-7-103  0.345
2010 Kalamvoki M, Roizman B. Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal. Journal of Virology. 84: 4222-8. PMID 20164233 DOI: 10.1128/JVI.02585-09  0.504
2009 Gu H, Poon AP, Roizman B. During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins. Proceedings of the National Academy of Sciences of the United States of America. 106: 19132-7. PMID 19850872 DOI: 10.1073/Pnas.0910920106  0.51
2009 Kalamvoki M, Roizman B. ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 14576-80. PMID 19706544 DOI: 10.1073/pnas.0906905106  0.477
2009 Taddeo B, Zhang W, Roizman B. The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes. Proceedings of the National Academy of Sciences of the United States of America. 106: 12139-44. PMID 19584246 DOI: 10.1073/pnas.0905828106  0.524
2009 Gu H, Roizman B. Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1. Journal of Virology. 83: 4376-85. PMID 19193804 DOI: 10.1128/Jvi.02515-08  0.524
2009 Davison AJ, Eberle R, Ehlers B, Hayward GS, McGeoch DJ, Minson AC, Pellett PE, Roizman B, Studdert MJ, Thiry E. The order Herpesvirales. Archives of Virology. 154: 171-7. PMID 19066710 DOI: 10.1007/S00705-008-0278-4  0.555
2009 Gu H, Roizman B. The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem. Journal of Virology. 83: 181-7. PMID 18945770 DOI: 10.1128/Jvi.01940-08  0.521
2009 Spiguel LR, Vosicky J, Weichselbaum RR, Roizman B, Skelly CL. Attenuated herpes simplex virus blocks neointimal hyperplasia induced by balloon injury and low shear stress in a dose-dependent fashion Journal of the American College of Surgeons. 209. DOI: 10.1016/J.Jamcollsurg.2009.06.349  0.31
2008 Kalamvoki M, Roizman B. Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 105: 20488-93. PMID 19073918 DOI: 10.1073/pnas.0810879105  0.533
2008 Durand LO, Roizman B. Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1. Journal of Virology. 82: 10591-9. PMID 18753202 DOI: 10.1128/Jvi.01242-08  0.843
2008 Liang L, Roizman B. Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase. Journal of Virology. 82: 4688-96. PMID 18321964 DOI: 10.1128/JVI.02763-07  0.531
2008 Smith-Donald BA, Durand LO, Roizman B. Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication. Journal of Virology. 82: 4527-32. PMID 18272575 DOI: 10.1128/Jvi.02021-07  0.826
2008 Smith-Donald BA, Roizman B. The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13. Journal of Virology. 82: 4533-43. PMID 18272572 DOI: 10.1128/Jvi.02022-07  0.824
2008 Jovasevic V, Liang L, Roizman B. Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus. Journal of Virology. 82: 3311-9. PMID 18216103 DOI: 10.1128/Jvi.01919-07  0.504
2008 Kalamvoki M, Qu J, Roizman B. Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene. Journal of Virology. 82: 1701-13. PMID 18057247 DOI: 10.1128/JVI.02157-07  0.561
2008 Yang K, Poon AP, Roizman B, Baines JD. Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature. Journal of Virology. 82: 487-94. PMID 17913813 DOI: 10.1128/Jvi.01875-07  0.442
2007 Gu H, Roizman B. Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 17134-9. PMID 17939992 DOI: 10.1073/Pnas.0707266104  0.549
2007 Khodarev NN, Minn AJ, Efimova EV, Darga TE, Labay E, Beckett M, Mauceri HJ, Roizman B, Weichselbaum RR. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Research. 67: 9214-20. PMID 17909027 DOI: 10.1158/0008-5472.CAN-07-1019  0.323
2007 Veerapong J, Bickenbach KA, Shao MY, Smith KD, Posner MC, Roizman B, Weichselbaum RR. Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity. Cancer Research. 67: 8301-6. PMID 17804745 DOI: 10.1158/0008-5472.CAN-07-1499  0.359
2007 Sciortino MT, Taddeo B, Giuffrè-Cuculletto M, Medici MA, Mastino A, Roizman B. Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase. Journal of Virology. 81: 10924-32. PMID 17670820 DOI: 10.1128/JVI.01239-07  0.529
2007 Benetti L, Roizman B. In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3. Journal of Virology. 81: 10242-8. PMID 17634220 DOI: 10.1128/JVI.00820-07  0.502
2007 Skelly CL, Chandiwal A, Vosicky JE, Weichselbaum RR, Roizman B. Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow. Proceedings of the National Academy of Sciences of the United States of America. 104: 12474-8. PMID 17626787 DOI: 10.1073/pnas.0705429104  0.312
2007 Taddeo B, Sciortino MT, Zhang W, Roizman B. Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA. Proceedings of the National Academy of Sciences of the United States of America. 104: 12163-8. PMID 17620619 DOI: 10.1073/pnas.0705245104  0.482
2007 Kari I, Syrjänen S, Johansson B, Peri P, He B, Roizman B, Hukkanen V. Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA. Virology Journal. 4: 47. PMID 17547759 DOI: 10.1186/1743-422X-4-47  0.353
2007 Kalamvoki M, Roizman B. Bcl-2 blocks accretion or depletion of stored calcium but has no effect on the redistribution of IP3 receptor I mediated by glycoprotein E of herpes simplex virus 1. Journal of Virology. 81: 6316-25. PMID 17409148 DOI: 10.1128/JVI.00311-07  0.425
2007 Zhou G, Roizman B. Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 4142-6. PMID 17360490 DOI: 10.1073/pnas.0611565104  0.381
2007 Poon AP, Roizman B. Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides. Journal of Virology. 81: 1980-9. PMID 17151133 DOI: 10.1128/JVI.02265-06  0.432
2007 Baines JD, Wills E, Jacob RJ, Pennington J, Roizman B. Glycoprotein M of herpes simplex virus 1 is incorporated into virions during budding at the inner nuclear membrane. Journal of Virology. 81: 800-12. PMID 17079321 DOI: 10.1128/Jvi.01756-06  0.452
2007 Roizman B, Taddeo B. The strategy of herpes simplex virus replication and takeover of the host cell Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. 163-174. DOI: 10.1017/CBO9780511545313.014  0.357
2007 Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B, Whitley R, Yamanishi K. Human herpesviruses: Biology, therapy, and immunoprophylaxis Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. 1-1410. DOI: 10.1017/CBO9780511545313  0.408
2007 Shao MY, Veerapong J, Bickenbach K, Smith KD, Roizman B, Weichselbaum RR, Posner MC. Systemic delivery by intravenous injection of gamma-1-34.5-deleted HSV-1 for oncolytic viral therapy Journal of the American College of Surgeons. 205. DOI: 10.1016/J.Jamcollsurg.2007.06.219  0.308
2006 Advani SJ, Mezhir JJ, Roizman B, Weichselbaum RR. ReVOLT: radiation-enhanced viral oncolytic therapy. International Journal of Radiation Oncology, Biology, Physics. 66: 637-46. PMID 17011442 DOI: 10.1016/j.ijrobp.2006.06.034  0.362
2006 Taddeo B, Roizman B. The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A. Journal of Virology. 80: 9341-5. PMID 16940547 DOI: 10.1128/JVI.01008-06  0.415
2006 Liang L, Roizman B. Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA. Journal of Virology. 80: 7756-9. PMID 16840355 DOI: 10.1128/JVI.00587-06  0.505
2006 Poon AP, Gu H, Roizman B. ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. Proceedings of the National Academy of Sciences of the United States of America. 103: 9993-8. PMID 16785443 DOI: 10.1073/Pnas.0604142103  0.519
2006 Campadelli-Fiume G, Roizman B. The egress of herpesviruses from cells: the unanswered questions. Journal of Virology. 80: 6716-7; author repli. PMID 16775362 DOI: 10.1128/JVI.00386-06  0.45
2006 Poon AP, Benetti L, Roizman B. U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress. Journal of Virology. 80: 3752-64. PMID 16571792 DOI: 10.1128/JVI.80.8.3752-3764.2006  0.421
2006 Zhou G, Roizman B. Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 5508-13. PMID 16554374 DOI: 10.1073/pnas.0601258103  0.461
2006 Liang Y, Roizman B. State and role of SRC family kinases in replication of herpes simplex virus 1. Journal of Virology. 80: 3349-59. PMID 16537602 DOI: 10.1128/Jvi.80.7.3349-3359.2006  0.605
2006 Benetti L, Roizman B. Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1. Journal of Virology. 80: 3341-8. PMID 16537601 DOI: 10.1128/JVI.80.7.3341-3348.2006  0.531
2006 Taddeo B, Zhang W, Roizman B. The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 2827-32. PMID 16477041 DOI: 10.1073/pnas.0510712103  0.489
2006 Smith KD, Mezhir JJ, Bickenbach K, Veerapong J, Charron J, Posner MC, Roizman B, Weichselbaum RR. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. Journal of Virology. 80: 1110-20. PMID 16414988 DOI: 10.1128/JVI.80.3.1110-1120.2006  0.506
2006 Kamiyama H, Zhou G, Roizman B. Herpes simplex virus 1 recombinant virions exhibiting the amino terminal fragment of urokinase-type plasminogen activator can enter cells via the cognate receptor. Gene Therapy. 13: 621-9. PMID 16292350 DOI: 10.1038/sj.gt.3302685  0.437
2005 Mezhir JJ, Advani SJ, Smith KD, Darga TE, Poon AP, Schmidt H, Posner MC, Roizman B, Weichselbaum RR. Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. Cancer Research. 65: 9479-84. PMID 16230412 DOI: 10.1158/0008-5472.CAN-05-1927  0.493
2005 Roizman B, Gu H, Mandel G. The first 30 minutes in the life of a virus: unREST in the nucleus. Cell Cycle (Georgetown, Tex.). 4: 1019-21. PMID 16082207 DOI: 10.4161/Cc.4.8.1902  0.557
2005 Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro-Oncology. 7: 213-24. PMID 16053696 DOI: 10.1215/S1152851705000074  0.428
2005 Poon AP, Roizman B. Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions. Journal of Virology. 79: 8470-9. PMID 15956590 DOI: 10.1128/JVI.79.13.8470-8479.2005  0.521
2005 Gu H, Liang Y, Mandel G, Roizman B. Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 7571-6. PMID 15897453 DOI: 10.1073/Pnas.0502658102  0.629
2005 Durand LO, Advani SJ, Poon AP, Roizman B. The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1. Journal of Virology. 79: 6757-62. PMID 15890914 DOI: 10.1128/Jvi.79.11.6757-6762.2005  0.833
2005 Zhou G, Roizman B. Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells. Journal of Virology. 79: 5272-7. PMID 15827141 DOI: 10.1128/JVI.79.9.5272-5277.2005  0.414
2005 Liang Y, Kurakin A, Roizman B. Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces. Proceedings of the National Academy of Sciences of the United States of America. 102: 5838-43. PMID 15824310 DOI: 10.1073/Pnas.0501253102  0.567
2005 Smith KD, Mezhir J, Roizman B, Weichselbaum R, Posner M. Identification of a novel MEK signaling pathway that determines tumor selective replication of herpes simplex type-1 (HSV-1) viruses in pancreatic cancer Journal of the American College of Surgeons. 201. DOI: 10.1016/J.Jamcollsurg.2005.06.187  0.326
2005 Advani SJ, Mezhir JJ, Smith KD, Darga T, Roizman B, Weichselbaum RR. Radiation Assisted Viral Oncolytic Therapy (RaVOLT): IR Activates HSV-1 Viral Promoters to Enhance Viral Replication and Tumor Eradication International Journal of Radiation Oncology Biology Physics. 63. DOI: 10.1016/J.Ijrobp.2005.07.290  0.391
2004 Esclatine A, Taddeo B, Roizman B. The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs. Proceedings of the National Academy of Sciences of the United States of America. 101: 18165-70. PMID 15596716 DOI: 10.1073/pnas.0408272102  0.49
2004 Taddeo B, Esclatine A, Roizman B. Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells. Biochemical Society Transactions. 32: 697-701. PMID 15493991 DOI: 10.1042/BST0320697  0.529
2004 Pagano JS, Blaser M, Buendia MA, Damania B, Khalili K, Raab-Traub N, Roizman B. Infectious agents and cancer: criteria for a causal relation. Seminars in Cancer Biology. 14: 453-71. PMID 15489139 DOI: 10.1016/J.Semcancer.2004.06.009  0.382
2004 Taddeo B, Zhang W, Lakeman F, Roizman B. Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus. Journal of Virology. 78: 11615-21. PMID 15479802 DOI: 10.1128/JVI.78.21.11615-11621.2004  0.499
2004 Esclatine A, Taddeo B, Roizman B. Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs. Journal of Virology. 78: 8582-92. PMID 15280467 DOI: 10.1128/JVI.78.16.8582-8592.2004  0.541
2004 Benetti L, Roizman B. Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 9411-6. PMID 15192152 DOI: 10.1073/pnas.0403160101  0.494
2004 Chee AV, Roizman B. Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. Journal of Virology. 78: 4185-96. PMID 15047834 DOI: 10.1128/JVI.78.8.4185-4196.2004  0.81
2004 Esclatine A, Taddeo B, Evans L, Roizman B. The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific. Proceedings of the National Academy of Sciences of the United States of America. 101: 3603-8. PMID 14993598 DOI: 10.1073/pnas.0400354101  0.416
2004 Hagglund R, Roizman B. Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1. Journal of Virology. 78: 2169-78. PMID 14963113 DOI: 10.1128/Jvi.78.5.2169-2178.2004  0.851
2004 Khodarev NN, Beckett M, Labay E, Darga T, Roizman B, Weichselbaum RR. STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1714-9. PMID 14755057 DOI: 10.1073/pnas.0308102100  0.308
2003 Hagglund R, Roizman B. Herpes simplex virus 1 mutant in which the ICP0 HUL-1 E3 ubiquitin ligase site is disrupted stabilizes cdc34 but degrades D-type cyclins and exhibits diminished neurotoxicity. Journal of Virology. 77: 13194-202. PMID 14645576 DOI: 10.1128/Jvi.77.24.13194-13202.2003  0.821
2003 Poon AP, Liang Y, Roizman B. Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0. Journal of Virology. 77: 12671-8. PMID 14610189 DOI: 10.1128/Jvi.77.23.12671-12678.2003  0.657
2003 Advani SJ, Durand LO, Weichselbaum RR, Roizman B. Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1. Journal of Virology. 77: 11927-32. PMID 14581529 DOI: 10.1128/Jvi.77.22.11927-11932.2003  0.847
2003 Taddeo B, Luo TR, Zhang W, Roizman B. Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12408-13. PMID 14530405 DOI: 10.1073/pnas.2034952100  0.513
2003 Gu H, Roizman B. The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5a. Proceedings of the National Academy of Sciences of the United States of America. 100: 8963-8. PMID 12855769 DOI: 10.1073/Pnas.1533420100  0.386
2003 Chee AV, Lopez P, Pandolfi PP, Roizman B. Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects. Journal of Virology. 77: 7101-5. PMID 12768029 DOI: 10.1128/Jvi.77.12.7101-7105.2003  0.802
2003 Curi MA, Skelly CL, Meyerson SL, Baldwin ZK, Balasubramanian V, Advani SJ, Glagov S, Roizman B, Weichselbaum RR, Schwartz LB. Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virus. Journal of Vascular Surgery. 37: 1294-300. PMID 12764278 DOI: 10.1016/S0741-5214(02)75333-0  0.4
2003 Benetti L, Munger J, Roizman B. The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD. Journal of Virology. 77: 6567-73. PMID 12743316 DOI: 10.1128/Jvi.77.11.6567-6573.2003  0.701
2003 Taddeo B, Esclatine A, Zhang W, Roizman B. The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene. Journal of Virology. 77: 6178-87. PMID 12743274 DOI: 10.1128/JVI.77.11.6178-6187.2003  0.55
2003 Advani SJ, Weichselbaum RR, Roizman B. Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 4825-30. PMID 12665617 DOI: 10.1073/pnas.0730735100  0.504
2003 Zhou G, Avitabile E, Campadelli-Fiume G, Roizman B. The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1. Journal of Virology. 77: 3759-67. PMID 12610150 DOI: 10.1128/JVI.77.6.3759-3767.2003  0.446
2003 Munger J, Hagglund R, Roizman B. Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis. Virology. 305: 364-70. PMID 12573581 DOI: 10.1006/Viro.2002.1728  0.843
2002 Taddeo B, Esclatine A, Roizman B. The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene. Proceedings of the National Academy of Sciences of the United States of America. 99: 17031-6. PMID 12481033 DOI: 10.1073/pnas.252588599  0.501
2002 Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B. Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 8: 551-63. PMID 12427216 DOI: 10.1046/j.1469-0691.2002.00432.x  0.522
2002 Zhou G, Ye GJ, Debinski W, Roizman B. Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction. Proceedings of the National Academy of Sciences of the United States of America. 99: 15124-9. PMID 12417744 DOI: 10.1073/Pnas.232588699  0.417
2002 Zhou G, Roizman B. Truncated forms of glycoprotein D of herpes simplex virus 1 capable of blocking apoptosis and of low-efficiency entry into cells form a heterodimer dependent on the presence of a cysteine located in the shared transmembrane domains. Journal of Virology. 76: 11469-75. PMID 12388708 DOI: 10.1128/JVI.76.22.11469-11475.2002  0.382
2002 Poon AP, Silverstein SJ, Roizman B. An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0. Journal of Virology. 76: 9744-55. PMID 12208953 DOI: 10.1128/JVI.76.19.9744-9755.2002  0.537
2002 Lopez P, Jacob RJ, Roizman B. Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins. Journal of Virology. 76: 9355-67. PMID 12186918 DOI: 10.1128/JVI.76.18.9355-9367.2002  0.575
2002 Whitley RJ, Roizman B. Herpes simplex viruses: is a vaccine tenable? The Journal of Clinical Investigation. 110: 145-51. PMID 12122103 DOI: 10.1172/JCI16126  0.425
2002 Trgovcich J, Johnson D, Roizman B. Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1. Journal of Virology. 76: 6974-86. PMID 12072498 DOI: 10.1128/JVI.76.14.6974-6986.2002  0.5
2002 Sciortino MT, Taddeo B, Poon AP, Mastino A, Roizman B. Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 8318-23. PMID 12060774 DOI: 10.1073/pnas.122231699  0.52
2002 Hagglund R, Roizman B. Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0. Proceedings of the National Academy of Sciences of the United States of America. 99: 7889-94. PMID 12060736 DOI: 10.1073/Pnas.122246999  0.814
2002 Zhou G, Roizman B. Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein. Journal of Virology. 76: 6197-204. PMID 12021353 DOI: 10.1128/JVI.76.12.6197-6204.2002  0.446
2002 Hagglund R, Van Sant C, Lopez P, Roizman B. Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes. Proceedings of the National Academy of Sciences of the United States of America. 99: 631-6. PMID 11805320 DOI: 10.1073/Pnas.022531599  0.821
2002 Cassady KA, Gross M, Gillespie GY, Roizman B. Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence. Journal of Virology. 76: 942-9. PMID 11773369 DOI: 10.1128/Jvi.76.3.942-949.2002  0.511
2002 Hagglund R, Munger J, Poon AP, Roizman B. U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. Journal of Virology. 76: 743-54. PMID 11752164 DOI: 10.1128/Jvi.76.2.743-754.2002  0.835
2002 Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE, Rubin DH. Fundamental Virology, 4th Edition; and Fields Virology, 4th Edition, Volumes I and II:Fundamental Virology, 4th Edition;Fields Virology, 4th Edition, Volumes I and II Clinical Infectious Diseases. 34: 1029-1030. DOI: 10.1086/339330  0.462
2001 Roizman B, Whitley RJ. The nine ages of herpes simplex virus. Herpes : the Journal of the Ihmf. 8: 23-7. PMID 11867013  0.341
2001 Skelly CL, Curi MA, Meyerson SL, Woo DH, Hari D, Vosicky JE, Advani SJ, Mauceri HJ, Glagov S, Roizman B, Weichselbaum RR, Schwartz LB. Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo. Gene Therapy. 8: 1840-6. PMID 11821937 DOI: 10.1038/Sj.Gt.3301597  0.395
2001 Weichselbaum RR, Kufe DW, Advani SJ, Roizman B. Molecular targeting of gene therapy and radiotherapy. Acta Oncologica (Stockholm, Sweden). 40: 735-8. PMID 11765068 DOI: 10.1080/02841860152619151  0.313
2001 Advani SJ, Weichselbaum RR, Roizman B. cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor. Journal of Virology. 75: 10326-33. PMID 11581401 DOI: 10.1128/JVI.75.21.10326-10333.2001  0.457
2001 Munger J, Roizman B. The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 10410-5. PMID 11517326 DOI: 10.1073/Pnas.181344498  0.729
2001 Sciortino MT, Suzuki M, Taddeo B, Roizman B. RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions. Journal of Virology. 75: 8105-16. PMID 11483756 DOI: 10.1128/JVI.75.17.8105-8116.2001  0.399
2001 Advani SJ, Hagglund R, Weichselbaum RR, Roizman B. Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize. Journal of Virology. 75: 7904-12. PMID 11483735 DOI: 10.1128/Jvi.75.17.7904-7912.2001  0.827
2001 Van Sant C, Hagglund R, Lopez P, Roizman B. The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity. Proceedings of the National Academy of Sciences of the United States of America. 98: 8815-20. PMID 11447293 DOI: 10.1073/Pnas.161283098  0.804
2001 Broberg E, Setälä N, Röyttä M, Salmi A, Erälinna JP, He B, Roizman B, Hukkanen V. Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis. Gene Therapy. 8: 769-77. PMID 11420640 DOI: 10.1038/Sj.Gt.3301465  0.375
2001 Zhou G, Roizman B. The domains of glycoprotein D required to block apoptosis depend on whether glycoprotein D is present in the virions carrying herpes simplex virus 1 genome lacking the gene encoding the glycoprotein. Journal of Virology. 75: 6166-72. PMID 11390618 DOI: 10.1128/JVI.75.13.6166-6172.2001  0.397
2001 Whitley RJ, Roizman B. Herpes simplex virus infections. Lancet. 357: 1513-8. PMID 11377626 DOI: 10.1016/S0140-6736(00)04638-9  0.441
2001 Munger J, Chee AV, Roizman B. The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. Journal of Virology. 75: 5491-7. PMID 11356956 DOI: 10.1128/Jvi.75.12.5491-5497.2001  0.824
2001 Lopez P, Van Sant C, Roizman B. Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1. Journal of Virology. 75: 3832-40. PMID 11264372 DOI: 10.1128/JVI.75.8.3832-3840.2001  0.536
2001 Kawaguchi Y, Tanaka M, Yokoymama A, Matsuda G, Kato K, Kagawa H, Hirai K, Roizman B. Herpes simplex virus 1 alpha regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1. Proceedings of the National Academy of Sciences of the United States of America. 98: 1877-82. PMID 11172044 DOI: 10.1073/pnas.041592598  0.535
2001 Van Sant C, Lopez P, Advani SJ, Roizman B. Role of cyclin D3 in the biology of herpes simplex virus 1 ICPO. Journal of Virology. 75: 1888-98. PMID 11160688 DOI: 10.1128/JVI.75.4.1888-1898.2001  0.428
2000 Zhou G, Galvan V, Campadelli-Fiume G, Roizman B. Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. Journal of Virology. 74: 11782-91. PMID 11090178 DOI: 10.1128/Jvi.74.24.11782-11791.2000  0.569
2000 Poon AP, Ogle WO, Roizman B. Posttranslational processing of infected cell protein 22 mediated by viral protein kinases is sensitive to amino acid substitutions at distant sites and can be cell-type specific. Journal of Virology. 74: 11210-4. PMID 11070018 DOI: 10.1128/JVI.74.23.11210-11214.2000  0.746
2000 Markovitz NS, Roizman B. Replication-competent herpes simplex viral vectors for cancer therapy. Advances in Virus Research. 55: 409-24. PMID 11050949 DOI: 10.1016/S0065-3527(00)55010-6  0.45
2000 Ye GJ, Roizman B. The essential protein encoded by the UL31 gene of herpes simplex virus 1 depends for its stability on the presence of UL34 protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 11002-7. PMID 11005871 DOI: 10.1073/Pnas.97.20.11002  0.468
2000 Advani SJ, Weichselbaum RR, Roizman B. The role of cdc2 in the expression of herpes simplex virus genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 10996-1001. PMID 10995483 DOI: 10.1073/pnas.200375297  0.538
2000 Zhou G, Roizman B. Wild-type herpes simplex virus 1 blocks programmed cell death and release of cytochrome c but not the translocation of mitochondrial apoptosis-inducing factor to the nuclei of human embryonic lung fibroblasts. Journal of Virology. 74: 9048-53. PMID 10982349 DOI: 10.1128/JVI.74.19.9048-9053.2000  0.488
2000 Randall G, Lagunoff M, Roizman B. Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice. Journal of Virology. 74: 9019-27. PMID 10982346 DOI: 10.1128/Jvi.74.19.9019-9027.2000  0.437
2000 Advani SJ, Weichselbaum RR, Roizman B. E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1. Journal of Virology. 74: 7842-50. PMID 10933691 DOI: 10.1128/JVI.74.17.7842-7850.2000  0.496
2000 Galvan V, Brandimarti R, Munger J, Roizman B. Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells. Journal of Virology. 74: 1931-8. PMID 10644366 DOI: 10.1128/Jvi.74.4.1931-1938.2000  0.722
2000 Ward PL, Taddeo B, Markovitz NS, Roizman B. Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome. Virology. 266: 275-85. PMID 10639314 DOI: 10.1006/viro.1999.0081  0.398
2000 Ye GJ, Vaughan KT, Vallee RB, Roizman B. The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. Journal of Virology. 74: 1355-63. PMID 10627546 DOI: 10.1128/JVI.74.3.1355-1363.2000  0.491
2000 Markovitz NS, Roizman B. Small dense nuclear bodies are the site of localization of herpes simplex virus 1 U(L)3 and U(L)4 proteins and of ICP22 only when the latter protein is present. Journal of Virology. 74: 523-8. PMID 10590143 DOI: 10.1128/Jvi.74.1.523-528.2000  0.426
2000 Advani SJ, Brandimarti R, Weichselbaum RR, Roizman B. The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes. Journal of Virology. 74: 8-15. PMID 10590085  0.441
2000 Advani SJ, Brandimarti R, Weichselbaum RR, Roizman B. The Disappearance of Cyclins A and B and the Increase in Activity of the G2/M-Phase Cellular Kinase cdc2 in Herpes Simplex Virus 1-Infected Cells Require Expression of the α22/US1.5 and UL13 Viral Genes Journal of Virology. 74: 8-15. DOI: 10.1128/Jvi.74.1.8-15.2000  0.521
1999 Roizman B. HSV gene functions: what have we learned that could be generally applicable to its near and distant cousins? Acta Virologica. 43: 75-80. PMID 10696424  0.452
1999 Khodarev NN, Advani SJ, Gupta N, Roizman B, Weichselbaum RR. Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 96: 12062-7. PMID 10518576 DOI: 10.1073/pnas.96.21.12062  0.545
1999 Markovitz NS, Filatov F, Roizman B. The U(L)3 protein of herpes simplex virus 1 is translated predominantly from the second in-frame methionine codon and is subject to at least two posttranslational modifications. Journal of Virology. 73: 8010-8. PMID 10482549 DOI: 10.1128/Jvi.73.10.8010-8018.1999  0.472
1999 Talarico CL, Burnette TC, Miller WH, Smith SL, Davis MG, Stanat SC, Ng TI, He Z, Coen DM, Roizman B, Biron KK. Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein. Antimicrobial Agents and Chemotherapy. 43: 1941-6. PMID 10428917 DOI: 10.1128/Aac.43.8.1941  0.491
1999 Van Sant C, Kawaguchi Y, Roizman B. A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proceedings of the National Academy of Sciences of the United States of America. 96: 8184-9. PMID 10393969 DOI: 10.1073/pnas.96.14.8184  0.534
1999 McCormick L, Igarashi K, Roizman B. Posttranscriptional regulation of US11 in cells infected with a herpes simplex virus 1 recombinant lacking both 222-bp domains containing S-component origins of DNA synthesis. Virology. 259: 286-98. PMID 10388653 DOI: 10.1006/viro.1999.9790  0.568
1999 Ryncarz AJ, Goddard J, Wald A, Huang ML, Roizman B, Corey L. Development of a high-throughput quantitative assay for detecting herpes simplex virus DNA in clinical samples. Journal of Clinical Microbiology. 37: 1941-7. PMID 10325351 DOI: 10.1128/Jcm.37.6.1941-1947.1999  0.327
1999 Jahedi S, Markovitz NS, Filatov F, Roizman B. Colocalization of the herpes simplex virus 1 UL4 protein with infected cell protein 22 in small, dense nuclear structures formed prior to onset of DNA synthesis. Journal of Virology. 73: 5132-8. PMID 10233976 DOI: 10.1128/Jvi.73.6.5132-5136.1999  0.526
1999 Kawaguchi Y, Matsumura T, Roizman B, Hirai K. Cellular elongation factor 1delta is modified in cells infected with representative alpha-, beta-, or gammaherpesviruses. Journal of Virology. 73: 4456-60. PMID 10196346 DOI: 10.1128/Jvi.73.5.4456-4460.1999  0.517
1999 Ogle WO, Roizman B. Functional anatomy of herpes simplex virus 1 overlapping genes encoding infected-cell protein 22 and US1.5 protein. Journal of Virology. 73: 4305-15. PMID 10196329 DOI: 10.1128/Jvi.73.5.4305-4315.1999  0.747
1999 Bruni R, Fineschi B, Ogle WO, Roizman B. A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection. Journal of Virology. 73: 3810-7. PMID 10196275 DOI: 10.1128/Jvi.73.5.3810-3817.1999  0.747
1999 Galvan V, Brandimarti R, Roizman B. Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death. Journal of Virology. 73: 3219-26. PMID 10074175 DOI: 10.1128/Jvi.73.4.3219-3226.1999  0.421
1999 Perbal B, Martinerie C, Sainson R, Werner M, He B, Roizman B. The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 869-74. PMID 9927660 DOI: 10.1073/Pnas.96.3.869  0.366
1999 Talarico CL, Burnette TC, Miller WH, Smith SL, Davis MG, Stanat SC, Ng TI, He Z, Coen DM, Roizman B, Biron KK. Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein Antimicrobial Agents and Chemotherapy. 43: 1941-1946. DOI: 10.1128/aac.43.8.1941  0.39
1999 Chung S, Advani SJ, Bradley JD, Kataoka Y, Roizman B, Weichselbaum RR. 2042 A novel therapeutic approach for hepatocellular carcinoma using replication-competent herpes simplex virus and ionizing radiation International Journal of Radiation Oncology Biology Physics. 45: 299. DOI: 10.1016/S0360-3016(99)90312-7  0.343
1998 Blaho JA, Roizman B. Analyses of HSV Proteins for Posttranslational Modifications and Enzyme Functions. Methods in Molecular Medicine. 10: 237-56. PMID 21374234 DOI: 10.1385/0-89603-347-3:237  0.52
1998 Cassady KA, Gross M, Roizman B. The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2. Journal of Virology. 72: 8620-6. PMID 9765401 DOI: 10.1128/Jvi.72.11.8620-8626.1998  0.532
1998 Bruni R, Roizman B. Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells. Journal of Virology. 72: 8525-31. PMID 9765390 DOI: 10.1128/Jvi.72.11.8525-8531.1998  0.501
1998 Cassady KA, Gross M, Roizman B. The second-site mutation in the herpes simplex virus recombinants lacking the gamma134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2alpha. Journal of Virology. 72: 7005-11. PMID 9696792 DOI: 10.1128/Jvi.72.9.7005-7011.1998  0.529
1998 He B, Gross M, Roizman B. The gamma134.5 protein of herpes simplex virus 1 has the structural and functional attributes of a protein phosphatase 1 regulatory subunit and is present in a high molecular weight complex with the enzyme in infected cells. The Journal of Biological Chemistry. 273: 20737-43. PMID 9694816 DOI: 10.1074/Jbc.273.33.20737  0.453
1998 Chang YE, Menotti L, Filatov F, Campadelli-Fiume G, Roizman B. UL27.5 is a novel gamma2 gene antisense to the herpes simplex virus 1 gene encoding glycoprotein B. Journal of Virology. 72: 6056-64. PMID 9621069 DOI: 10.1128/Jvi.72.7.6056-6064.1998  0.488
1998 Advani SJ, Sibley GS, Song PY, Hallahan DE, Kataoka Y, Roizman B, Weichselbaum RR. Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors. Gene Therapy. 5: 160-5. PMID 9578834 DOI: 10.1038/Sj.Gt.3300546  0.399
1998 Andreansky S, He B, van Cott J, McGhee J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Therapy. 5: 121-30. PMID 9536273 DOI: 10.1038/Sj.Gt.3300550  0.358
1998 Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex viruses. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 26: 541-53; quiz 554-5. PMID 9524821 DOI: 10.1086/514600  0.446
1998 Galvan V, Roizman B. Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 95: 3931-6. PMID 9520470 DOI: 10.1073/Pnas.95.7.3931  0.515
1998 Ward PL, Avitabile E, Campadelli-Fiume G, Roizman B. Conservation of the architecture of the Golgi apparatus related to a differential organization of microtubules in polykaryocytes induced by syn- mutants of herpes simplex virus 1. Virology. 241: 189-99. PMID 9499794 DOI: 10.1006/viro.1997.8972  0.51
1998 Kawaguchi Y, Van Sant C, Roizman B. Eukaryotic elongation factor 1delta is hyperphosphorylated by the protein kinase encoded by the U(L)13 gene of herpes simplex virus 1. Journal of Virology. 72: 1731-6. PMID 9499021 DOI: 10.1128/Jvi.72.3.1731-1736.1998  0.574
1998 Ng TI, Ogle WO, Roizman B. UL13 protein kinase of herpes simplex virus 1 complexes with glycoprotein E and mediates the phosphorylation of the viral Fc receptor: glycoproteins E and I. Virology. 241: 37-48. PMID 9454715 DOI: 10.1006/viro.1997.8963  0.765
1998 Bradley J, Advani S, Chung S, Gillespie Y, Markert J, Whitley RJ, Roizman B, Weichselbaum RR. The use of concomitant radiotherapy and an attenuated herpes simplex-1 virus improves survival, in intracranial glioblastoma multiforme tumors (astro research fellowship) International Journal of Radiation Oncology*Biology*Physics. 42: 151. DOI: 10.1016/S0360-3016(98)80155-7  0.323
1997 Brandimarti R, Roizman B. Us9, a stable lysine-less herpes simplex virus 1 protein, is ubiquitinated before packaging into virions and associates with proteasomes. Proceedings of the National Academy of Sciences of the United States of America. 94: 13973-8. PMID 9391137 DOI: 10.1073/pnas.94.25.13973  0.552
1997 Chang YE, Van Sant C, Krug PW, Sears AE, Roizman B. The null mutant of the U(L)31 gene of herpes simplex virus 1: construction and phenotype in infected cells. Journal of Virology. 71: 8307-15. PMID 9343183 DOI: 10.1128/Jvi.71.11.8307-8315.1997  0.568
1997 Mitchell C, Blaho JA, McCormick AL, Roizman B. The nucleotidylylation of herpes simplex virus 1 regulatory protein alpha22 by human casein kinase II. The Journal of Biological Chemistry. 272: 25394-400. PMID 9312161 DOI: 10.1074/jbc.272.40.25394  0.375
1997 Randall G, Roizman B. Transcription of the derepressed open reading frame P of herpes simplex virus 1 precludes the expression of the antisense gamma(1)34.5 gene and may account for the attenuation of the mutant virus. Journal of Virology. 71: 7750-7. PMID 9311860 DOI: 10.1128/Jvi.71.10.7750-7757.1997  0.504
1997 Kawaguchi Y, Van Sant C, Roizman B. Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. Journal of Virology. 71: 7328-36. PMID 9311810 DOI: 10.1128/Jvi.71.10.7328-7336.1997  0.528
1997 Randall G, Lagunoff M, Roizman B. The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site. Proceedings of the National Academy of Sciences of the United States of America. 94: 10379-84. PMID 9294219 DOI: 10.1073/Pnas.94.19.10379  0.469
1997 Ogle WO, Ng TI, Carter KL, Roizman B. The UL13 protein kinase and the infected cell type are determinants of posttranslational modification of ICP0. Virology. 235: 406-13. PMID 9281521 DOI: 10.1006/viro.1997.8710  0.782
1997 Ng TI, Chang YE, Roizman B. Infected cell protein 22 of herpes simplex virus 1 regulates the expression of virion host shutoff gene U(L)41. Virology. 234: 226-34. PMID 9268153 DOI: 10.1006/viro.1997.8659  0.542
1997 He B, Chou J, Brandimarti R, Mohr I, Gluzman Y, Roizman B. Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene. Journal of Virology. 71: 6049-54. PMID 9223497 DOI: 10.1128/Jvi.71.8.6049-6054.1997  0.531
1997 Leopardi R, Van Sant C, Roizman B. The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus. Proceedings of the National Academy of Sciences of the United States of America. 94: 7891-6. PMID 9223283 DOI: 10.1073/pnas.94.15.7891  0.559
1997 Markovitz NS, Baunoch D, Roizman B. The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1. Journal of Virology. 71: 5560-9. PMID 9188630 DOI: 10.1128/Jvi.71.7.5560-5569.1997  0.522
1997 Roizman B, Markovitz N. Herpes simplex virus virulence: the functions of the gamma (1)34.5 gene. Journal of Neurovirology. 3: S1-2. PMID 9179780  0.33
1997 Poon AP, Roizman B. Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant gamma (1)34.5 genes of herpes simplex virus 1. Virology. 229: 98-105. PMID 9123882 DOI: 10.1006/viro.1996.8425  0.566
1997 He B, Gross M, Roizman B. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 843-8. PMID 9023344 DOI: 10.1073/Pnas.94.3.843  0.516
1997 Leopardi R, Ward PL, Ogle WO, Roizman B. Association of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase. Journal of Virology. 71: 1133-9. PMID 8995634 DOI: 10.1128/Jvi.71.2.1133-1139.1997  0.786
1997 Kawaguchi Y, Bruni R, Roizman B. Interaction of herpes simplex virus 1 alpha regulatory protein ICP0 with elongation factor 1delta: ICP0 affects translational machinery. Journal of Virology. 71: 1019-24. PMID 8995621 DOI: 10.1128/Jvi.71.2.1019-1024.1997  0.548
1997 Advani SJ, Kataoka Y, Sibley GS, Song PY, Hallahan DE, Roizman B, Weichselbaum RR. 2021 Enhanced replication of attenuated HSV-1 in irradiated human glioma xenografts International Journal of Radiation Oncology*Biology*Physics. 39: 251. DOI: 10.1016/S0360-3016(97)80791-2  0.328
1996 AURELIAN L, ROIZMAN B. ABORTIVE INFECTION OF CANINE CELLS BY HERPES SIMPLEX VIRUS. II. ALTERNATIVE SUPPRESSION OF SYNTHESIS OF INTERFERON AND VIRAL CONSTITUENTS. Journal of Molecular Biology. 11: 539-48. PMID 14267275 DOI: 10.1016/S0022-2836(65)80009-2  0.487
1996 ROIZMAN B, AURELIAN L. ABORTIVE INFECTION OF CANINE CELLS BY HERPES SIMPLEX VIRUS. I. CHARACTERIZATION OF VIRAL PROGENY FROM CO-OPERATIVE INFECTION WITH MUTANTS DIFFERING IN CAPACITY TO MULTIPLY IN CANINE CELLS. Journal of Molecular Biology. 11: 528-38. PMID 14267274 DOI: 10.1016/S0022-2836(65)80008-0  0.462
1996 AURELIAN L, ROIZMAN B. THE HOST RANGE OF HERPES SIMPLEX VIRUS; INTERFERON, VIRAL DNA, AND ANTIGEN SYNTHESIS IN ABORTIVE INFECTION OF DOG KIDNEY CELLS. Virology. 22: 452-61. PMID 14166105 DOI: 10.1016/0042-6822(64)90066-2  0.511
1996 ROIZMAN B, AURELIAN L, ROANE PR. THE MULTIPLICATION OF HERPES SIMPLEX VIRUS. I. THE PROGRAMMING OF VIRAL DNA DUPLICATION IN HEP-2 CELLS. Virology. 21: 482-98. PMID 14081372 DOI: 10.1016/0042-6822(63)90209-5  0.507
1996 Nalwanga D, Rempel S, Roizman B, Baines JD. The UL 16 gene product of herpes simplex virus 1 is a virion protein that colocalizes with intranuclear capsid proteins. Virology. 226: 236-42. PMID 8955043 DOI: 10.1006/Viro.1996.0651  0.572
1996 Ng TI, Talarico C, Burnette TC, Biron K, Roizman B. Partial substitution of the functions of the herpes simplex virus 1 U(L)13 gene by the human cytomegalovirus U(L)97 gene. Virology. 225: 347-58. PMID 8918921 DOI: 10.1006/viro.1996.0609  0.501
1996 Carter KL, Roizman B. Alternatively spliced mRNAs predicted to yield frame-shift proteins and stable intron 1 RNAs of the herpes simplex virus 1 regulatory gene alpha 0 accumulate in the cytoplasm of infected cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 12535-40. PMID 8901617 DOI: 10.1073/Pnas.93.22.12535  0.485
1996 Carter KL, Ward PL, Roizman B. Characterization of the products of the U(L)43 gene of herpes simplex virus 1: potential implications for regulation of gene expression by antisense transcription. Journal of Virology. 70: 7663-8. PMID 8892886 DOI: 10.1128/Jvi.70.11.7663-7668.1996  0.427
1996 Andreansky SS, He B, Gillespie GY, Soroceanu L, Markert J, Chou J, Roizman B, Whitley RJ. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 93: 11313-8. PMID 8876132 DOI: 10.1073/Pnas.93.21.11313  0.365
1996 Roizman B. The function of herpes simplex virus genes: a primer for genetic engineering of novel vectors. Proceedings of the National Academy of Sciences of the United States of America. 93: 11307-12. PMID 8876131 DOI: 10.1073/Pnas.93.21.11307  0.475
1996 Palese P, Roizman B. Genetic engineering of viruses and of virus vectors: a preface. Proceedings of the National Academy of Sciences of the United States of America. 93: 11287. PMID 8876127 DOI: 10.1073/Pnas.93.21.11287  0.369
1996 Bruni R, Roizman B. Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA. Proceedings of the National Academy of Sciences of the United States of America. 93: 10423-7. PMID 8816816 DOI: 10.1073/Pnas.93.19.10423  0.532
1996 Leopardi R, Roizman B. The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia. Proceedings of the National Academy of Sciences of the United States of America. 93: 9583-7. PMID 8790373 DOI: 10.1073/Pnas.93.18.9583  0.531
1996 Ward PL, Ogle WO, Roizman B. Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1. Journal of Virology. 70: 4623-31. PMID 8676489 DOI: 10.1128/Jvi.70.7.4623-4631.1996  0.757
1996 Chang YE, Poon AP, Roizman B. Properties of the protein encoded by the UL32 open reading frame of herpes simplex virus 1. Journal of Virology. 70: 3938-46. PMID 8648731 DOI: 10.1128/Jvi.70.6.3938-3946.1996  0.525
1996 Leopardi R, Roizman B. Functional interaction and colocalization of the herpes simplex virus 1 major regulatory protein ICP4 with EAP, a nucleolar-ribosomal protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 4572-6. PMID 8643445 DOI: 10.1073/Pnas.93.10.4572  0.533
1996 Roller RJ, Monk LL, Stuart D, Roizman B. Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitro. Journal of Virology. 70: 2842-51. PMID 8627758 DOI: 10.1128/Jvi.70.5.2842-2851.1996  0.423
1996 Ward PL, Barker DE, Roizman B. A novel herpes simplex virus 1 gene, UL43.5, maps antisense to the UL43 gene and encodes a protein which colocalizes in nuclear structures with capsid proteins. Journal of Virology. 70: 2684-90. PMID 8627741 DOI: 10.1128/Jvi.70.5.2684-2690.1996  0.525
1996 Lagunoff M, Randall G, Roizman B. Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene. Journal of Virology. 70: 1810-7. PMID 8627705 DOI: 10.1128/Jvi.70.3.1810-1817.1996  0.531
1996 He B, Chou J, Liebermann DA, Hoffman B, Roizman B. The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells. Journal of Virology. 70: 84-90. PMID 8523596 DOI: 10.1128/Jvi.70.1.84-90.1996  0.546
1996 Carter KL, Roizman B. The promoter and transcriptional unit of a novel herpes simplex virus 1 alpha gene are contained in, and encode a protein in frame with, the open reading frame of the alpha 22 gene. Journal of Virology. 70: 172-8. PMID 8523523 DOI: 10.1128/Jvi.70.1.172-178.1996  0.458
1996 He B, Chou J, Liebermann DA, Hoffman B, Roizman B. The carboxyl terminus of the murine MyD116 gene substitutes for the corresponding domain of the gamma(1)34.5 gene of herpes simplex virus to preclude the premature shutoff of total protein synthesis in infected human cells. Journal of Virology. 70: 84-90. DOI: 10.1128/jvi.70.1.84-90.1996  0.424
1996 Song PY, Sibley GS, Advani S, Hallahan D, Hyland J, Kufe DW, Chou J, Roizman B, Weichselbaum RR. 137 Enhanced tumor control of human glioblastoma multiforme xenografts with the concomitant use of radiotherapy and an attentuated herpes simplex-1 virus (ASTRO Research Fellowship) International Journal of Radiation Oncology*Biology*Physics. 36: 227. DOI: 10.1016/S0360-3016(97)85479-X  0.347
1995 Chambers R, Gillespie GY, Soroceanu L, Andreansky S, Chatterjee S, Chou J, Roizman B, Whitley RJ. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 92: 1411-5. PMID 7877992 DOI: 10.1073/pnas.92.5.1411  0.364
1995 Baines JD, Jacob RJ, Simmerman L, Roizman B. The herpes simplex virus 1 UL11 proteins are associated with cytoplasmic and nuclear membranes and with nuclear bodies of infected cells. Journal of Virology. 69: 825-33. PMID 7815549 DOI: 10.1128/Jvi.69.2.825-833.1995  0.487
1995 Lagunoff M, Roizman B. The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome. Journal of Virology. 69: 3615-23. PMID 7745709 DOI: 10.1128/jvi.69.6.3615-3623.1995  0.543
1995 Leopardi R, Michael N, Roizman B. Repression of the herpes simplex virus 1 alpha 4 gene by its gene product (ICP4) within the context of the viral genome is conditioned by the distance and stereoaxial alignment of the ICP4 DNA binding site relative to the TATA box. Journal of Virology. 69: 3042-8. PMID 7707531 DOI: 10.1128/Jvi.69.5.3042-3048.1995  0.371
1995 Bohenzky RA, Lagunoff M, Roizman B, Wagner EK, Silverstein S. Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1. Journal of Virology. 69: 2889-97. PMID 7707513 DOI: 10.1128/Jvi.69.5.2889-2897.1995  0.442
1995 Roizman B. New viral footprints in Kaposi's sarcoma. The New England Journal of Medicine. 332: 1227-8. PMID 7700319 DOI: 10.1056/NEJM199505043321810  0.312
1995 Poon AP, Roizman B. The phenotype in vitro and in infected cells of herpes simplex virus 1 alpha trans-inducing factor (VP16) carrying temperature-sensitive mutations introduced by substitution of cysteines. Journal of Virology. 69: 7658-67. PMID 7494274 DOI: 10.1128/Jvi.69.12.7658-7667.1995  0.481
1995 Avitabile E, Di Gaeta S, Torrisi MR, Ward PL, Roizman B, Campadelli-Fiume G. Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis. Journal of Virology. 69: 7472-82. PMID 7494253 DOI: 10.1128/Jvi.69.12.7472-7482.1995  0.55
1995 Chou J, Chen JJ, Gross M, Roizman B. Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 92: 10516-20. PMID 7479831 DOI: 10.1073/PNAS.92.23.10516  0.568
1995 Sibley GS, Hallahan DE, Hyland J, Seung LP, Mauceri HJ, Chou J, Roizman B, Weichselbaum RR. 64 evaluation of a gene therapy system using a replication competent, non-neurovirulent HSV-1 viral vector used tn combination with radiotherapy International Journal of Radiation Oncology*Biology*Physics. 32: 173. DOI: 10.1016/0360-3016(95)97729-K  0.382
1994 Brandimarti R, Huang T, Roizman B, Campadelli-Fiume G. Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection. Proceedings of the National Academy of Sciences of the United States of America. 91: 5406-10. PMID 8202498 DOI: 10.1073/Pnas.91.12.5406  0.503
1994 Chou J, Roizman B. Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 91: 5247-51. PMID 8202476 DOI: 10.1073/pnas.91.12.5247  0.465
1994 Baines JD, Koyama AH, Huang T, Roizman B. The UL21 gene products of herpes simplex virus 1 are dispensable for growth in cultured cells. Journal of Virology. 68: 2929-36. PMID 8151763 DOI: 10.1128/Jvi.68.5.2929-2936.1994  0.565
1994 Roller RJ, Roizman B. A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein D. Journal of Virology. 68: 2830-9. PMID 8151754 DOI: 10.1128/Jvi.68.5.2830-2839.1994  0.519
1994 Lagunoff M, Roizman B. Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript. Journal of Virology. 68: 6021-8. PMID 8057477 DOI: 10.1128/jvi.68.9.6021-6028.1994  0.467
1994 Blaho JA, Mitchell C, Roizman B. An amino acid sequence shared by the herpes simplex virus 1 alpha regulatory proteins 0, 4, 22, and 27 predicts the nucleotidylylation of the UL21, UL31, UL47, and UL49 gene products. The Journal of Biological Chemistry. 269: 17401-10. PMID 8021242  0.394
1994 Mitchell C, Blaho JA, Roizman B. Casein kinase II specifically nucleotidylylates in vitro the amino acid sequence of the protein encoded by the alpha 22 gene of herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 91: 11864-8. PMID 7991547 DOI: 10.1073/Pnas.91.25.11864  0.511
1994 Chou J, Poon AP, Johnson J, Roizman B. Differential response of human cells to deletions and stop codons in the gamma(1)34.5 gene of herpes simplex virus. Journal of Virology. 68: 8304-11. PMID 7966624 DOI: 10.1128/Jvi.68.12.8304-8311.1994  0.51
1994 Baines JD, Poon AP, Rovnak J, Roizman B. The herpes simplex virus 1 UL15 gene encodes two proteins and is required for cleavage of genomic viral DNA. Journal of Virology. 68: 8118-24. PMID 7966602 DOI: 10.1128/Jvi.68.12.8118-8124.1994  0.58
1994 Ward PL, Roizman B. Herpes simplex genes: the blueprint of a successful human pathogen. Trends in Genetics : Tig. 10: 267-74. PMID 7940755 DOI: 10.1016/0168-9525(90)90009-U  0.529
1994 Ward PL, Campadelli-Fiume G, Avitabile E, Roizman B. Localization and putative function of the UL20 membrane protein in cells infected with herpes simplex virus 1. Journal of Virology. 68: 7406-17. PMID 7933124 DOI: 10.1128/Jvi.68.11.7406-7417.1994  0.437
1994 Avitabile E, Ward PL, Di Lazzaro C, Torrisi MR, Roizman B, Campadelli-Fiume G. The herpes simplex virus UL20 protein compensates for the differential disruption of exocytosis of virions and viral membrane glycoproteins associated with fragmentation of the Golgi apparatus. Journal of Virology. 68: 7397-405. PMID 7933123 DOI: 10.1128/Jvi.68.11.7397-7405.1994  0.529
1994 Roizman B, Joklik W, Fields B, Moss B. The destruction of smallpox virus stocks in national repositories: a grave mistake and a bad precedent. Infectious Agents and Disease. 3: 215-7. PMID 7866654  0.314
1994 Roizman B, Spear PG. Current frontiers in virology. Infectious Agents and Disease. 3: 53. PMID 7812654  0.426
1994 Fawl RL, Roizman B. The molecular basis of herpes simplex virus pathogenicity Seminars in Virology. 5: 261-271. DOI: 10.1006/Smvy.1994.1029  0.511
1993 Purves FC, Ogle WO, Roizman B. Processing of the herpes simplex virus regulatory protein alpha 22 mediated by the UL13 protein kinase determines the accumulation of a subset of alpha and gamma mRNAs and proteins in infected cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 6701-5. PMID 8393574 DOI: 10.1073/Pnas.90.14.6701  0.774
1993 Whitley RJ, Kern ER, Chatterjee S, Chou J, Roizman B. Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models. The Journal of Clinical Investigation. 91: 2837-43. PMID 8390490 DOI: 10.1172/JCI116527  0.453
1993 Georgopoulou U, Michaelidou A, Roizman B, Mavromara-Nazos P. Identification of a new transcriptional unit that yields a gene product within the unique sequences of the short component of the herpes simplex virus 1 genome. Journal of Virology. 67: 3961-8. PMID 8389914 DOI: 10.1128/Jvi.67.7.3961-3968.1993  0.402
1993 Blaho JA, Mitchell C, Roizman B. Guanylylation and adenylylation of the alpha regulatory proteins of herpes simplex virus require a viral beta or gamma function. Journal of Virology. 67: 3891-900. PMID 8389911 DOI: 10.1128/Jvi.67.7.3891-3900.1993  0.511
1993 Campadelli G, Brandimarti R, Di Lazzaro C, Ward PL, Roizman B, Torrisi MR. Fragmentation and dispersal of Golgi proteins and redistribution of glycoproteins and glycolipids processed through the Golgi apparatus after infection with herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 90: 2798-802. PMID 8385343 DOI: 10.1073/Pnas.90.7.2798  0.52
1993 Michael N, Roizman B. Repression of the herpes simplex virus 1 alpha 4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sites. Proceedings of the National Academy of Sciences of the United States of America. 90: 2286-90. PMID 8384719 DOI: 10.1073/Pnas.90.6.2286  0.441
1993 Igarashi K, Fawl R, Roller RJ, Roizman B. Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis. Journal of Virology. 67: 2123-32. PMID 8383234 DOI: 10.1128/Jvi.67.4.2123-2132.1993  0.548
1993 Liu F, Roizman B. Characterization of the protease and other products of amino-terminus-proximal cleavage of the herpes simplex virus 1 UL26 protein. Journal of Virology. 67: 1300-9. PMID 8382296 DOI: 10.1128/Jvi.67.3.1300-1309.1993  0.398
1993 DiIanni CL, Drier DA, Deckman IC, McCann PJ, Liu F, Roizman B, Colonno RJ, Cordingley MG. Identification of the herpes simplex virus-1 protease cleavage sites by direct sequence analysis of autoproteolytic cleavage products. The Journal of Biological Chemistry. 268: 2048-51. PMID 8380586  0.35
1993 Poon AP, Roizman B. Characterization of a temperature-sensitive mutant of the UL15 open reading frame of herpes simplex virus 1. Journal of Virology. 67: 4497-503. PMID 8331721 DOI: 10.1128/Jvi.67.8.4497-4503.1993  0.481
1993 Fawl RL, Roizman B. Induction of reactivation of herpes simplex virus in murine sensory ganglia in vivo by cadmium. Journal of Virology. 67: 7025-31. PMID 8230427 DOI: 10.1128/Jvi.67.12.7025-7031.1993  0.466
1993 Chang YE, Roizman B. The product of the UL31 gene of herpes simplex virus 1 is a nuclear phosphoprotein which partitions with the nuclear matrix. Journal of Virology. 67: 6348-56. PMID 7692079 DOI: 10.1128/Jvi.67.11.6348-6356.1993  0.477
1993 Baines JD, Roizman B. The UL10 gene of herpes simplex virus 1 encodes a novel viral glycoprotein, gM, which is present in the virion and in the plasma membrane of infected cells. Journal of Virology. 67: 1441-52. PMID 7679747 DOI: 10.1128/Jvi.67.3.1441-1452.1993  0.413
1992 Barker DE, Roizman B, Kovler MB. Molecular biology of herpes simplex virus. Molecular and Cell Biology of Human Diseases Series. 1: 259-81. PMID 1341646  0.311
1992 Blaho JA, Michael N, Kang V, Aboul-Ela N, Smulson ME, Jacobson MK, Roizman B. Differences in the poly(ADP-ribosyl)ation patterns of ICP4, the herpes simplex virus major regulatory protein, in infected cells and in isolated nuclei. Journal of Virology. 66: 6398-407. PMID 1328673 DOI: 10.1128/Jvi.66.11.6398-6407.1992  0.478
1992 Purves FC, Roizman B. The UL13 gene of herpes simplex virus 1 encodes the functions for posttranslational processing associated with phosphorylation of the regulatory protein alpha 22. Proceedings of the National Academy of Sciences of the United States of America. 89: 7310-4. PMID 1323829 DOI: 10.1073/Pnas.89.16.7310  0.501
1992 Baines JD, Roizman B. The cDNA of UL15, a highly conserved herpes simplex virus 1 gene, effectively replaces the two exons of the wild-type virus. Journal of Virology. 66: 5621-6. PMID 1323715 DOI: 10.1128/Jvi.66.9.5621-5626.1992  0.506
1992 Baines JD, Roizman B. The UL11 gene of herpes simplex virus 1 encodes a function that facilitates nucleocapsid envelopment and egress from cells. Journal of Virology. 66: 5168-74. PMID 1321297 DOI: 10.1128/Jvi.66.8.5168-5174.1992  0.56
1992 Romanelli MG, Mavromara-Nazos P, Spector D, Roizman B. Mutational analysis of the ICP4 binding sites in the 5' transcribed noncoding domains of the herpes simplex virus 1 UL 49.5 gamma 2 gene. Journal of Virology. 66: 4855-63. PMID 1321274 DOI: 10.1128/Jvi.66.8.4855-4863.1992  0.473
1992 Purves FC, Spector D, Roizman B. UL34, the target of the herpes simplex virus U(S)3 protein kinase, is a membrane protein which in its unphosphorylated state associates with novel phosphoproteins. Journal of Virology. 66: 4295-303. PMID 1318405 DOI: 10.1128/Jvi.66.7.4295-4303.1992  0.521
1992 Roller RJ, Roizman B. The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunits. Journal of Virology. 66: 3624-32. PMID 1316472 DOI: 10.1128/Jvi.66.6.3624-3632.1992  0.498
1992 McCormick L, Roller RJ, Roizman B. Characterization of a herpes simplex virus sequence which binds a cellular protein as either a single-stranded or double-stranded DNA or RNA. Journal of Virology. 66: 3435-47. PMID 1316459 DOI: 10.1128/Jvi.66.6.3435-3447.1992  0.421
1992 Chou J, Roizman B. The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 3266-70. PMID 1314384 DOI: 10.1073/Pnas.89.8.3266  0.524
1992 Liu F, Roizman B. Differentiation of multiple domains in the herpes simplex virus 1 protease encoded by the UL26 gene. Proceedings of the National Academy of Sciences of the United States of America. 89: 2076-80. PMID 1312713 DOI: 10.1073/Pnas.89.6.2076  0.346
1992 Barker DE, Roizman B. The unique sequence of the herpes simplex virus 1 L component contains an additional translated open reading frame designated UL49.5. Journal of Virology. 66: 562-6. PMID 1309263 DOI: 10.1128/Jvi.66.1.562-566.1992  0.524
1991 Roizman B, Baines J. The diversity and unity of Herpesviridae. Comparative Immunology, Microbiology and Infectious Diseases. 14: 63-79. PMID 1935001 DOI: 10.1016/0147-9571(91)90122-T  0.348
1991 Sears AE, Hukkanen V, Labow MA, Levine AJ, Roizman B. Expression of the herpes simplex virus 1 alpha transinducing factor (VP16) does not induce reactivation of latent virus or prevent the establishment of latency in mice. Journal of Virology. 65: 2929-35. PMID 1851865 DOI: 10.1128/Jvi.65.6.2929-2935.1991  0.435
1991 Campadelli-Fiume G, Farabegoli F, Di Gaeta S, Roizman B. Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1. Journal of Virology. 65: 1589-95. PMID 1847476 DOI: 10.1128/Jvi.65.3.1589-1595.1991  0.517
1991 Baines JD, Roizman B. The open reading frames UL3, UL4, UL10, and UL16 are dispensable for the replication of herpes simplex virus 1 in cell culture. Journal of Virology. 65: 938-44. PMID 1846207 DOI: 10.1128/Jvi.65.2.938-944.1991  0.453
1991 Liu FY, Roizman B. The promoter, transcriptional unit, and coding sequence of herpes simplex virus 1 family 35 proteins are contained within and in frame with the UL26 open reading frame. Journal of Virology. 65: 206-12. PMID 1845885 DOI: 10.1128/Jvi.65.1.206-212.1991  0.424
1991 Baines JD, Ward PL, Campadelli-Fiume G, Roizman B. The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress. Journal of Virology. 65: 6414-24. PMID 1719228 DOI: 10.1128/Jvi.65.12.6414-6424.1991  0.54
1991 Roizman B. Introduction: objectives of herpes simplex virus vaccines seen from a historical perspective. Reviews of Infectious Diseases. 13: S892-4. PMID 1664123 DOI: 10.1093/Clind/13.Supplement_11.S892  0.329
1991 Roller RJ, Roizman B. Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA. Journal of Virology. 65: 5873-9. PMID 1656075 DOI: 10.1128/Jvi.65.11.5873-5879.1991  0.494
1991 Purves FC, Spector D, Roizman B. The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 gene. Journal of Virology. 65: 5757-64. PMID 1656069 DOI: 10.1128/Jvi.65.11.5757-5764.1991  0.53
1991 Liu FY, Roizman B. The herpes simplex virus 1 gene encoding a protease also contains within its coding domain the gene encoding the more abundant substrate. Journal of Virology. 65: 5149-56. PMID 1654435 DOI: 10.1128/Jvi.65.10.5149-5156.1991  0.449
1991 Sears AE, McGwire BS, Roizman B. Infection of polarized MDCK cells with herpes simplex virus 1: two asymmetrically distributed cell receptors interact with different viral proteins. Proceedings of the National Academy of Sciences of the United States of America. 88: 5087-91. PMID 1647025 DOI: 10.1073/Pnas.88.12.5087  0.475
1991 Blaho JA, Roizman B. ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated. Journal of Virology. 65: 3759-69. PMID 1645791 DOI: 10.1128/Jvi.65.7.3759-3769.1991  0.386
1991 Spector D, Purves F, Roizman B. Role of alpha-transinducing factor (VP16) in the induction of alpha genes within the context of viral genomes. Journal of Virology. 65: 3504-13. PMID 1645782 DOI: 10.1128/Jvi.65.7.3504-3513.1991  0.381
1990 Sears AE, Roizman B. Amplification by host cell factors of a sequence contained within the herpes simplex virus 1 genome. Proceedings of the National Academy of Sciences of the United States of America. 87: 9441-4. PMID 2174562 DOI: 10.1073/Pnas.87.23.9441  0.446
1990 Chou J, Kern ER, Whitley RJ, Roizman B. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science (New York, N.Y.). 250: 1262-6. PMID 2173860 DOI: 10.1126/science.2173860  0.495
1990 Campadelli-Fiume G, Qi S, Avitabile E, Foà-Tomasi L, Brandimarti R, Roizman B. Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus. Journal of Virology. 64: 6070-9. PMID 2173780 DOI: 10.1128/Jvi.64.12.6070-6079.1990  0.518
1990 Campadelli-Fiume G, Stirpe D, Boscaro A, Avitabile E, Foá-Tomasi L, Barker D, Roizman B. Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection. Virology. 178: 213-22. PMID 2167550 DOI: 10.1016/0042-6822(90)90396-9  0.556
1990 Meignier B, Martin B, Whitley RJ, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). The Journal of Infectious Diseases. 162: 313-21. PMID 2165104 DOI: 10.1093/infdis/162.2.313  0.424
1990 Barker DE, Roizman B. Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1. Virology. 177: 684-91. PMID 2164730 DOI: 10.1016/0042-6822(90)90534-X  0.409
1990 Spector D, Purves F, Roizman B. Mutational analysis of the promoter region of the alpha 27 gene of herpes simplex virus 1 within the context of the viral genome. Proceedings of the National Academy of Sciences of the United States of America. 87: 5268-72. PMID 2164672 DOI: 10.1073/Pnas.87.14.5268  0.362
1990 Roller RJ, Roizman B. The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein. Journal of Virology. 64: 3463-70. PMID 2161949 DOI: 10.1128/Jvi.64.7.3463-3470.1990  0.479
1990 Chou J, Roizman B. The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited-passage isolates but not in strain 17syn+. Journal of Virology. 64: 1014-20. PMID 2154589 DOI: 10.1128/Jvi.64.3.1014-1020.1990  0.391
1989 Meignier B, Roizman B. Genetic engineering and properties of novel herpes simplex viruses for use as potential vaccines and as vectors of foreign genes. Advances in Experimental Medicine and Biology. 257: 187-92. PMID 2559609 DOI: 10.1007/978-1-4684-5712-4_17  0.42
1989 Michael N, Roizman B. Binding of the herpes simplex virus major regulatory protein to viral DNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 9808-12. PMID 2557630 DOI: 10.1073/Pnas.86.24.9808  0.381
1989 Roller RJ, McCormick AL, Roizman B. Cellular proteins specifically bind single- and double-stranded DNA and RNA from the initiation site of a transcript that crosses the origin of DNA replication of herpes simplex virus 1. Proceedings of the National Academy of Sciences of the United States of America. 86: 6518-22. PMID 2549540 DOI: 10.1073/Pnas.86.17.6518  0.448
1989 Mavromara-Nazos P, Roizman B. Delineation of regulatory domains of early (beta) and late (gamma 2) genes by construction of chimeric genes expressed in herpes simplex virus 1 genomes. Proceedings of the National Academy of Sciences of the United States of America. 86: 4071-5. PMID 2542962 DOI: 10.1073/Pnas.86.11.4071  0.452
1989 Chou J, Roizman B. Characterization of DNA sequence-common and sequence-specific proteins binding to cis-acting sites for cleavage of the terminal a sequence of the herpes simplex virus 1 genome. Journal of Virology. 63: 1059-68. PMID 2536820 DOI: 10.1128/Jvi.63.3.1059-1068.1989  0.464
1988 Roizman B, Meignier B. Immunization against viral infections associated with human cancer: the promise of modern biotechnology. Ca: a Cancer Journal For Clinicians. 38: 95-103. PMID 3127002 DOI: 10.3322/Canjclin.38.2.95  0.354
1988 Campadelli-Fiume G, Avitabile E, Fini S, Stirpe D, Arsenakis M, Roizman B. Herpes simplex virus glycoprotein D is sufficient to induce spontaneous pH-independent fusion in a cell line that constitutively expresses the glycoprotein. Virology. 166: 598-602. PMID 3051654 DOI: 10.1016/0042-6822(88)90533-8  0.429
1988 Roizman B, Kristie T, McKnight JL, Michael N, Mavromara-Nazos P, Spector D. The trans-activation of herpes simplex virus gene expression: comparison of two factors and their cis sites. Biochimie. 70: 1031-43. PMID 2852507 DOI: 10.1016/0300-9084(88)90266-0  0.416
1988 Voss JH, Roizman B. Properties of two 5'-coterminal RNAs transcribed part way and across the S component origin of DNA synthesis of the herpes simplex virus 1 genome. Proceedings of the National Academy of Sciences of the United States of America. 85: 8454-8. PMID 2847162 DOI: 10.1073/Pnas.85.22.8454  0.558
1988 Meignier B, Longnecker R, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodents. The Journal of Infectious Diseases. 158: 602-14. PMID 2842408 DOI: 10.1093/Infdis/158.3.602  0.451
1988 Michael N, Spector D, Mavromara-Nazos P, Kristie TM, Roizman B. The DNA-binding properties of the major regulatory protein alpha 4 of herpes simplex viruses. Science (New York, N.Y.). 239: 1531-4. PMID 2832940 DOI: 10.1126/Science.2832940  0.427
1988 Arsenakis M, Campadelli-Fiume G, Lombardo MT, Roizman B. The glycoprotein C gene of herpes simplex virus 1 resident in clonal L cell lines manifests two regulatory domains conferring a dominant B and a subordinate γ2 regulation Virology. 162: 300-310. PMID 2829421 DOI: 10.1016/0042-6822(88)90469-2  0.466
1988 Meignier B, Longnecker R, Mavromara-Nazos P, Sears AE, Roizman B. Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1. Virology. 162: 251-4. PMID 2827384 DOI: 10.1016/0042-6822(88)90417-5  0.486
1988 Campadelli-Fiume G, Arsenakis M, Farabegoli F, Roizman B. Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus. Journal of Virology. 62: 159-167. PMID 2824844 DOI: 10.1128/Jvi.62.1.159-167.1988  0.511
1988 Arsenakis M, Campadelli-Fiume G, Roizman B. Regulation of glycoprotein D synthesis: does alpha 4, the major regulatory protein of herpes simplex virus 1, regulate late genes both positively and negatively? Journal of Virology. 62: 148-158. PMID 2824843 DOI: 10.1128/Jvi.62.1.148-158.1988  0.428
1988 Hubenthal-Voss J, Houghten RA, Pereira L, Roizman B. Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1. Journal of Virology. 62: 454-462. PMID 2447289 DOI: 10.1128/Jvi.62.2.454-462.1988  0.368
1987 Jenkins FJ, Roizman B. Site-specific mutagenesis of large DNA viral genomes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 5: 244-7. PMID 3551936 DOI: 10.1002/bies.950050603  0.337
1987 Purves FC, Longnecker RM, Leader DP, Roizman B. Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture. Journal of Virology. 61: 2896-901. PMID 3039176 DOI: 10.1128/Jvi.61.9.2896-2901.1987  0.56
1987 Longnecker R, Chatterjee S, Whitley RJ, Roizman B. Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 4303-7. PMID 3035578 DOI: 10.1073/Pnas.84.12.4303  0.487
1987 Longnecker R, Roizman B. Clustering of genes dispensable for growth in culture in the S component of the HSV-1 genome Science. 236: 573-576. PMID 3033823 DOI: 10.1126/Science.3033823  0.364
1987 Meignier B, Jourdier TM, Norrild B, Pereira L, Roizman B. Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: protection against challenge with virulent virus. The Journal of Infectious Diseases. 155: 921-930. PMID 3031174 DOI: 10.1093/Infdis/155.5.921  0.355
1987 McKnight JLC, Pellett PE, Jenkins FJ, Roizman B. Characterization and nucleotide sequence of two herpes simplex virus 1 genes whose products modulate α-trans-inducing factor-dependent activation of α genes Journal of Virology. 61: 992-1001. PMID 3029433 DOI: 10.1128/jvi.61.4.992-1001.1987  0.619
1987 Kristie TM, Roizman B. Host cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus 1 alpha genes Proceedings of the National Academy of Sciences of the United States of America. 84: 71-75. PMID 3025864 DOI: 10.1073/Pnas.84.1.71  0.376
1987 Roizman B, Sears AE. An inquiry into the mechanisms of herpes simplex virus latency. Annual Review of Microbiology. 41: 543-71. PMID 2825588 DOI: 10.1146/Annurev.Mi.41.100187.002551  0.431
1987 Mavromara-Nazos P, Roizman B. Activation of herpes simplex virus 1 γ2 genes by viral DNA replication Virology. 161: 593-598. PMID 2825424 DOI: 10.1016/0042-6822(87)90156-5  0.499
1987 McKnight JLC, Kristie TM, Roizman B. Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 7061-7065. PMID 2823252 DOI: 10.1073/Pnas.84.20.7061  0.421
1987 Hubenthal-Voss J, Starr L, Roizman B. The herpes simplex virus origins of DNA synthesis in the S component are each contained in a transcribed open reading frame Journal of Virology. 61: 3349-3355. PMID 2822945 DOI: 10.1128/Jvi.61.11.3349-3355.1987  0.397
1986 Pellett PE, Jenkins FJ, Ackermann M, Sarmiento M, Roizman B. Transcription initiation sites and nucleotide sequence of a herpes simplex virus 1 gene conserved in the Epstein-Barr virus genome and reported to affect the transport of viral glycoproteins Journal of Virology. 60: 1134-1140. PMID 3023664 DOI: 10.1128/jvi.60.3.1134-1140.1986  0.721
1986 Mavromara-Nazos P, Ackermann M, Roizman B. Construction and properties of a viable herpes simplex virus 1 recombinant lacking coding sequences of the alpha 47 gene. Journal of Virology. 60: 807-812. PMID 3022015 DOI: 10.1128/Jvi.60.2.807-812.1986  0.391
1986 Arsenakis M, Hubenthal-Voss J, Campadelli-Fiume G, Pereira L, Roizman B. Construction and properties of a cell line constitutively expressing the herpes simplex virus glycoprotein B dependent on functional alpha 4 protein synthesis. Journal of Virology. 60: 674-682. PMID 3022001 DOI: 10.1128/Jvi.60.2.674-682.1986  0.418
1986 Yehiely F, Thuning C, Meignier B, Norrild B, Warren J, Nahmias AJ, Rapp F, Roizman B, Frenkel N. Analyses of transplanted murine tumors for HSV DNA sequences. International Journal of Cancer. 38: 395-403. PMID 3017868 DOI: 10.1002/Ijc.2910380315  0.336
1986 Meignier B, Norrild B, Thuning C, Warren J, Frenkel N, Nahmias AJ, Rapp F, Roizman B. Failure to induce cervical cancer in mice by long-term frequent vaginal exposure to live or inactivated herpes simplex viruses. International Journal of Cancer. 38: 387-394. PMID 3017867 DOI: 10.1002/Ijc.2910380314  0.425
1986 Jenkins FJ, Roizman B. Herpes simplex virus 1 recombinants with noninverting genomes frozen in different isomeric arrangements are capable of independent replication. Journal of Virology. 59: 494-9. PMID 3016310 DOI: 10.1128/jvi.59.2.494-499.1986  0.392
1986 Kristie TM, Roizman B. DNA-binding site of major regulatory protein alpha 4 specifically associated with promoter-regulatory domains of alpha genes of herpes simplex virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 83: 4700-4704. PMID 3014505 DOI: 10.1073/Pnas.83.13.4700  0.392
1986 Kristie TM, Roizman B. Alpha 4, the major regulatory protein of herpes simplex virus type 1, is stably and specifically associated with promoter-regulatory domains of alpha genes and of selected other viral genes Proceedings of the National Academy of Sciences of the United States of America. 83: 3218-3222. PMID 3010285 DOI: 10.1073/Pnas.83.10.3218  0.413
1986 Longnecker R, Roizman B. Generation of an inverting herpes simplex virus 1 mutant lacking the L-S junction a sequences, an origin of DNA synthesis, and several genes including those specifying glycoprotein E and the alpha 47 gene. Journal of Virology. 58: 583-591. PMID 3009870 DOI: 10.1128/Jvi.58.2.583-591.1986  0.429
1986 Arsenakis M, Tomasi LF, Speziali V, Roizman B, Campadelli-Fiume G. Expression and regulation of glycoprotein C gene of herpes simplex virus 1 resident in a clonal L-cell line. Journal of Virology. 58: 367-376. PMID 3009854 DOI: 10.1128/Jvi.58.2.367-376.1986  0.522
1986 Ackermann M, Longnecker R, Roizman B, Pereira L. Identification, properties, and gene location of a novel glycoprotein specified by herpes simplex virus 1. Virology. 150: 207-220. PMID 3006335 DOI: 10.1016/0042-6822(86)90280-1  0.445
1986 Mavromara-Nazos P, Silver S, Hubenthal-Voss J, McKnight JLC, Roizman B. Regulation of herpes simplex virus 1 genes: α gene sequence requirements for transient induction of indicator genes regulated by β or late (γ2) promoters Virology. 149: 152-164. PMID 3004024 DOI: 10.1016/0042-6822(86)90117-0  0.338
1986 Chou J, Roizman B. The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component Journal of Virology. 57: 629-637. PMID 3003394 DOI: 10.1128/Jvi.57.2.629-637.1986  0.403
1986 Hummel M, Arsenakis M, Marchini A, Lee LA, Roizman B, Kieff E. Herpes simplex virus expressing Epstein-Barr virus nuclear antigen 1 Virology. 148: 337-348. PMID 3002038 DOI: 10.1016/0042-6822(86)90330-2  0.673
1986 Ackermann M, Chou J, Sarmiento M, Lerner RA, Roizman B. Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome. Journal of Virology. 58: 843-850. DOI: 10.1128/Jvi.58.3.843-850.1986  0.504
1985 Meignier B, Roizman B. Herpes simplex virus vaccines. Antiviral Research. 5: 259-265. PMID 3002260 DOI: 10.1016/S0166-3542(85)80036-X  0.33
1985 Pellett PE, Biggin MD, Barrell B, Roizman B. Epstein-Barr virus genome may encode a protein showing significant amino acid and predicted secondary structure homology with glycoprotein B of herpes simplex virus 1 Journal of Virology. 56: 807-813. PMID 2999435 DOI: 10.1128/Jvi.56.3.807-813.1985  0.656
1985 Roizman B, Jenkins FJ. Genetic engineering of novel genomes of large DNA viruses. Science (New York, N.Y.). 229: 1208-14. PMID 2994215 DOI: 10.1126/science.2994215  0.415
1985 Pellett PE, McKnight JLC, Jenkins FJ, Roizman B. Nucleotide sequence and predicted amino acid sequence of a protein encoded in a small herpes simplex virus DNA fragment capable of trans-inducing α genes Proceedings of the National Academy of Sciences of the United States of America. 82: 5870-5874. PMID 2994050 DOI: 10.1073/pnas.82.17.5870  0.682
1985 Ackermann M, Sarmiento M, Roizman B. Application of antibody to synthetic peptides for characterization of the intact and truncated alpha 22 protein specified by herpes simplex virus 1 and the R325 alpha 22- deletion mutant. Journal of Virology. 56: 207-215. PMID 2993651 DOI: 10.1128/Jvi.56.1.207-215.1985  0.491
1985 Jenkins FJ, Casadaban MJ, Roizman B. Application of the mini-Mu-phage for target-sequence-specific insertional mutagenesis of the herpes simplex virus genome. Proceedings of the National Academy of Sciences of the United States of America. 82: 4773-7. PMID 2991892 DOI: 10.1073/pnas.82.14.4773  0.445
1985 Sears AE, Meignier B, Roizman B. Establishment of latency in mice by herpes simplex virus 1 recombinants that carry insertions affecting regulation of the thymidine kinase gene. Journal of Virology. 55: 410-6. PMID 2991566 DOI: 10.1128/Jvi.55.2.410-416.1985  0.49
1985 Sears AE, Halliburton IW, Meignier B, Silver S, Roizman B. Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice. Journal of Virology. 55: 338-46. PMID 2991560 DOI: 10.1128/Jvi.55.2.338-346.1985  0.473
1985 Sears AE, Roizman B. Cell-specific selection of mutants of a herpes simplex virus recombinant carrying deletions. Virology. 145: 176-80. PMID 2990098 DOI: 10.1016/0042-6822(85)90213-2  0.491
1985 Chou J, Roizman B. Isomerization of herpes simplex virus 1 genome: identification of the cis-acting and recombination sites within the domain of the a sequence Cell. 41: 803-811. PMID 2988789 DOI: 10.1016/S0092-8674(85)80061-1  0.386
1985 Silver S, Roizman B. gamma 2-Thymidine kinase chimeras are identically transcribed but regulated a gamma 2 genes in herpes simplex virus genomes and as beta genes in cell genomes. Molecular and Cellular Biology. 5: 518-528. PMID 2985955 DOI: 10.1128/Mcb.5.3.518  0.502
1985 Hubenthal-Voss J, Roizman B. Herpes simplex virus 1 reiterated S component sequences (c1) situated between the a sequence and alpha 4 gene are not essential for virus replication. Journal of Virology. 54: 509-514. PMID 2985813 DOI: 10.1128/Jvi.54.2.509-514.1985  0.436
1985 Poffenberger KL, Roizman B. A noninverting genome of a viable herpes simplex virus 1: presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection. Journal of Virology. 53: 587-595. PMID 2982037 DOI: 10.1128/Jvi.53.2.587-595.1985  0.489
1985 Pellett PE, Kousoulas KG, Pereira L, Roizman B. Anatomy of the herpes simplex virus 1 strain F glycoprotein B gene: Primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants Journal of Virology. 53: 243-253. PMID 2981343 DOI: 10.1128/Jvi.53.1.243-253.1985  0.773
1984 Kristie TM, Roizman B. Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes Proceedings of the National Academy of Sciences of the United States of America. 81: 4065-4069. PMID 6330737 DOI: 10.1073/Pnas.81.13.4065  0.336
1984 Braun DK, Batterson W, Roizman B. Identification and genetic mapping of a herpes simplex virus capsid protein that binds DNA Journal of Virology. 50: 645-648. PMID 6323767 DOI: 10.1128/Jvi.50.2.645-648.1984  0.501
1984 Arsenakis M, Roizman B. A post-alpha gene function turns off the capacity of a host protein to bind DNA in cells infected with herpes simplex virus 1. Journal of Virology. 49: 813-818. PMID 6321766 DOI: 10.1128/Jvi.49.3.813-818.1984  0.551
1984 Braun DK, Roizman B, Pereira L. Characterization of post-translational products of herpes simplex virus gene 35 proteins binding to the surfaces of full capsids but not empty capsids. Journal of Virology. 49: 142-153. PMID 6317887 DOI: 10.1128/Jvi.49.1.142-153.1984  0.459
1984 Kousoulas KG, Pellettt PE, Pereira L, Roizman B. Mutations affecting conformation or sequence of neutralizing epitopes identified by reactivity of viable plaques segregate from syn and ts domains of HSV-1(F) gB gene Virology. 135: 379-394. PMID 6204443 DOI: 10.1016/0042-6822(84)90194-6  0.72
1984 Roizman B, Norrild B, Chan C, Pereira L. Identification and preliminary mapping with monoclonal antibodies of a herpes simplex virus 2 glycoprotein lacking a known type 1 counterpart Virology. 133: 242-247. PMID 6199891 DOI: 10.1016/0042-6822(84)90447-1  0.45
1984 Shih MF, Arsenakis M, Tiollais P, Roizman B. Expression of hepatitis B virus S gene by herpes simplex virus type 1 vectors carrying alpha- and beta-regulated gene chimeras. Proceedings of the National Academy of Sciences of the United States of America. 81: 5867-70. PMID 6091116 DOI: 10.1073/Pnas.81.18.5867  0.46
1984 Ackermann M, Braun DK, Pereira L, Roizman B. Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies. Journal of Virology. 52: 108-118. PMID 6090689 DOI: 10.1128/Jvi.52.1.108-118.1984  0.419
1983 Meignier B, Norrild B, Roizman B. Colonization of murine ganglia by a superinfecting strain of herpes simplex virus. Infection and Immunity. 41: 702-708. PMID 6307880 DOI: 10.1128/Iai.41.2.702-708.1983  0.395
1983 Roizman B, Tognon M. Restriction Endonuclease Patterns of Herpes Simplex Virus DNA: Application to Diagnosis and Molecular Epidemiology Current Topics in Microbiology and Immunology. 104: 273-286. PMID 6307594 DOI: 10.1007/978-3-642-68949-9_17  0.376
1983 Poffenberger KL, Tabares E, Roizman B. Characterization of a viable, noninverting herpes simplex virus 1 genome derived by insertion and deletion of sequences at the junction of components L and S. Proceedings of the National Academy of Sciences of the United States of America. 80: 2690-2694. PMID 6302700 DOI: 10.1073/Pnas.80.9.2690  0.441
1983 Batterson W, Roizman B. Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes. Journal of Virology. 46: 371-377. PMID 6302308 DOI: 10.1128/Jvi.46.2.371-377.1983  0.505
1983 Braun DK, Pereira L, Norrild B, Roizman B. Application of denatured, electrophoretically separated, and immobilized lysates of herpes simplex virus-infected cells for detection of monoclonal antibodies and for studies of the properties of viral proteins. Journal of Virology. 46: 103-112. PMID 6298448 DOI: 10.1128/Jvi.46.1.103-112.1983  0.4
1983 Batterson W, Furlong D, Roizman B. Molecular genetics of herpes simplex virus. VIII. further characterization of a temperature-sensitive mutant defective in release of viral DNA and in other stages of the viral reproductive cycle. Journal of Virology. 45: 397-407. PMID 6296445 DOI: 10.1128/Jvi.45.1.397-407.1983  0.48
1983 Herz C, Roizman B. The α promoter regulator-ovalbumin chimeric gene resident in human cells is regulated like the authentic α 4 gene after infection with herpes simplex virus 1 mutants in α 4 gene Cell. 33: 145-151. PMID 6088053 DOI: 10.1016/0092-8674(83)90343-4  0.383
1982 Mocarski ES, Roizman B. Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA Cell. 31: 89-97. PMID 6297756 DOI: 10.1016/0092-8674(82)90408-1  0.596
1982 Mackem S, Roizman B. Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes. Journal of Virology. 44: 939-949. PMID 6294341 DOI: 10.1128/Jvi.44.3.939-949.1982  0.36
1982 Pereira L, Dondero D, Roizman B. Herpes simplex virus glycoprotein gA/B: evidence that the infected Vero cell products comap and arise by proteolysis. Journal of Virology. 44: 88-97. PMID 6292507 DOI: 10.1128/Jvi.44.1.88-97.1982  0.416
1982 Mackem S, Roizman B. Regulation of α Genes of Herpes Simplex Virus: The α 27 Gene Promoter-Thymidine Kinase Chimera Is Positively Regulated in Converted L Cells Journal of Virology. 43: 1015-1023. PMID 6292445 DOI: 10.1128/Jvi.43.3.1015-1023.1982  0.409
1982 Mocarski ES, Roizman B. Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication Proceedings of the National Academy of Sciences of the United States of America. 79: 5626-5630. PMID 6291055 DOI: 10.1073/Pnas.79.18.5626  0.676
1982 Mackem S, Roizman B. Differentiation between alpha promoter and regulator regions of herpes simplex virus 1: the functional domains and sequence of a movable alpha regulator Proceedings of the National Academy of Sciences of the United States of America. 79: 4917-4921. PMID 6289323 DOI: 10.1073/Pnas.79.16.4917  0.36
1982 Whitley R, Lakeman AD, Nahmias A, Roizman B. Dna restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. The New England Journal of Medicine. 307: 1060-1062. PMID 6289100 DOI: 10.1056/Nejm198210213071706  0.434
1982 Post LE, Norrild B, Simpson T, Roizman B. Chicken ovalbumin gene fused to a Herpes simplex virus α promoter and linked to a thymidine kinase gene is regulated like a viral gene Molecular and Cellular Biology. 2: 233-240. PMID 6287232 DOI: 10.1128/Mcb.2.3.233  0.418
1982 Centifanto-Fitzgerald YM, Yamaguchi T, Kaufman HE, Tognon M, Roizman B. Ocular disease pattern induced by herpes simplex virus is genetically determined by a specific region of viral DNA. Journal of Experimental Medicine. 155: 475-489. PMID 6276491 DOI: 10.1084/Jem.155.2.475  0.305
1981 Tognon M, Furlong D, Conley AJ, Roizman B. Molecular genetics of herpes simplex virus. V. Characterization of a mutant defective in ability to form plaques at low temperatures and in a viral fraction which prevents accumulation of coreless capsids at nuclear pores late in infection. Journal of Virology. 40: 870-880. PMID 6275122 DOI: 10.1128/Jvi.40.3.870-880.1981  0.529
1981 Mocarski ES, Roizman B. Site specific inversion sequence of the herpes simplex virus genome: Domain and structural features Proceedings of the National Academy of Sciences of the United States of America. 78: 7047-7051. PMID 6273905 DOI: 10.1073/Pnas.78.11.7047  0.55
1981 Pereira L, Dondero D, Norrild B, Roizman B. Differential immunologic reactivity and processing of glycoproteins gA and gB of herpes simplex virus types 1 and 2 made in Vero and HEp-2 cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 5202-5206. PMID 6272294 DOI: 10.1073/Pnas.78.8.5202  0.403
1981 Studdert M, Simpson T, Roizman B. Differentiation of respiratory and abortigenic isolates of equine herpesvirus 1 by restriction endonucleases Science. 214: 562-564. PMID 6270790 DOI: 10.1126/Science.6270790  0.365
1981 Mackem S, Roizman B. Regulation of herpesvirus macromolecular synthesis: temporal order of transcription of alpha genes is not dependent on the stringency of inhibition of protein synthesis. Journal of Virology. 40: 319-322. PMID 6270385 DOI: 10.1128/Jvi.40.1.319-322.1981  0.456
1981 Post LE, Roizman B. A generalized technique for deletion of specific genes in large genomes: a gene 22 of herpes simplex virus 1 is not essential for growth Cell. 25: 227-232. PMID 6268303 DOI: 10.1016/0092-8674(81)90247-6  0.451
1981 Knipe DM, Batterson W, Nosal C, Roizman B, Buchan A. Molecular genetics of herpes simplex virus. VI. Characterization of a temperature-sensitive mutant defective in the expression of all early viral gene products Journal of Virology. 38: 539-547. PMID 6264126 DOI: 10.1128/Jvi.38.2.539-547.1981  0.681
1981 Post LE, Mackem S, Roizman B. Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters Cell. 24: 555-565. PMID 6263501 DOI: 10.1016/0092-8674(81)90346-9  0.426
1981 Conley AJ, Knipe DM, Jones PC, Roizman B. Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides. Journal of Virology. 37: 191-206. PMID 6260973 DOI: 10.1128/Jvi.37.1.191-206.1981  0.65
1981 Norrild B, Pedersen B, Roizman B. Immunological reactivity of herpes simplex virus 1 and 2 polypeptides electrophoretically separated and transferred to diazobenzyloxymethyl paper. Infection and Immunity. 31: 660-667. PMID 6260673 DOI: 10.1128/Iai.31.2.660-667.1981  0.414
1981 Adams G, Stover BH, Keenlyside RA, Hooton TM, Buchman TG, Roizman B, Stewart JA. Nosocomial Herpetic Infections In A Pediatric Intensive Care Unit American Journal of Epidemiology. 113: 126-132. PMID 6258425 DOI: 10.1093/Oxfordjournals.Aje.A113076  0.378
1980 Roizman B. Genome variation and evolution among herpes viruses. Annals of the New York Academy of Sciences. 354: 472-483. PMID 6261658 DOI: 10.1111/J.1749-6632.1980.Tb27986.X  0.304
1980 Buchman TG, Simpson T, Nosal C, Roizman B, Nahmias AJ. The Structure Of Herpes Simplex Virus Dna And Its Application To Molecular Epidemiology Annals of the New York Academy of Sciences. 354: 279-290. PMID 6261647 DOI: 10.1111/J.1749-6632.1980.Tb27972.X  0.411
1980 Mackem S, Roizman B. Regulation of herpesvirus macromolecular synthesis: transcription-initiation sites and domains of alpha genes Proceedings of the National Academy of Sciences of the United States of America. 77: 7122-7126. PMID 6261240 DOI: 10.1073/Pnas.77.12.7122  0.429
1980 Halliburton IW, Morse LS, Roizman B, Quinn KE. Mapping of the thymidine kinase genes of type 1 and type 2 herpes simplex viruses using intertypic recombinants. Journal of General Virology. 49: 235-253. PMID 6255066 DOI: 10.1099/0022-1317-49-2-235  0.37
1980 Post LE, Conley AJ, Mocarski ES, Roizman B. Cloning of reiterated and nonreiterated herpes simplex virus 1 sequences as BamHI fragments Proceedings of the National Academy of Sciences of the United States of America. 77: 4201-4205. PMID 6254015 DOI: 10.1073/Pnas.77.7.4201  0.612
1980 Mocarski ES, Post LE, Roizman B. Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions Cell. 22: 243-255. PMID 6253078 DOI: 10.1016/0092-8674(80)90172-5  0.622
1980 Lemaster S, Roizman B. Herpes simplex virus phosphoproteins. II. Characterization of the virion protein kinase and of the polypeptides phosphorylated in the virion. Journal of Virology. 35: 798-811. PMID 6252339 DOI: 10.1128/Jvi.35.3.798-811.1980  0.465
1980 Halperin SA, Hendley JO, Nosal C, Roizman B. DNA fingerprinting in investigation of apparent nosocomial acquisition of neonatal herpes simplex The Journal of Pediatrics. 97: 91-93. PMID 6247474 DOI: 10.1016/S0022-3476(80)80140-5  0.372
1980 Hammer SM, Buchman TG, D'Angelo LJ, Karchmer AW, Roizman B, Hirsch MS. Temporal Cluster of Herpes Simplex Encephalitis: Investigation by Restriction Endonuclease Cleavage of Viral DNA The Journal of Infectious Diseases. 141: 436-440. PMID 6246175 DOI: 10.1093/Infdis/141.4.436  0.336
1980 Wilcox KW, Kohn A, Sklyanskaya E, Roizman B. Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA Journal of Virology. 33: 167-182. PMID 6245226 DOI: 10.1128/Jvi.33.1.167-182.1980  0.525
1979 Roizman B. The Organization of the Herpes Simplex Virus Genomes Annual Review of Genetics. 13: 25-57. PMID 231931 DOI: 10.1146/Annurev.Ge.13.120179.000325  0.411
1979 Knipe DM, Ruyechan WT, Honess RW, Roizman B. Molecular genetics of herpes simplex virus: The terminal a sequences of the L and S components are obligatorily identical and constitute a part of a structural gene mapping predominantly in the S component Proceedings of the National Academy of Sciences of the United States of America. 76: 4534-4538. PMID 228300 DOI: 10.1073/Pnas.76.9.4534  0.588
1979 Buchman TG, Roizman B, Nahmias AJ. Demonstration of exogenous genital reinfection with herpes simplex virus type 2 by restriction endonuclease fingerprinting of viral DNA. The Journal of Infectious Diseases. 140: 295-304. PMID 227967 DOI: 10.1093/Infdis/140.3.295  0.435
1979 Roizman B, Jacob RJ, Knipe DM, Morse LS, Ruyechan WT. On the structure, functional equivalence, and replication of the four arrangements of herpes simplex virus DNA Cold Spring Harbor Symposia On Quantitative Biology. 43: 809-826. PMID 226324 DOI: 10.1101/Sqb.1979.043.01.088  0.619
1979 Jones PC, Roizman B. Regulation of herpesvirus macromolecular synthesis. VIII. The transcription program consists of three phases during which both extent of transcription and accumulation of RNA in the cytoplasm are regulated Journal of Virology. 31: 299-314. PMID 225555 DOI: 10.1128/Jvi.31.2.299-314.1979  0.434
1979 Roizman B. The structure and isomerization of herpes simplex virus genomes. Cell. 16: 481-494. PMID 222462 DOI: 10.1016/0092-8674(79)90023-0  0.385
1979 Fenwick M, Morse LS, Roizman B. Anatomy of herpes simplex virus DNA. XI. Apparent clustering of functions effecting rapid inhibition of host DNA and protein synthesis. Journal of Virology. 29: 825-827. PMID 219262 DOI: 10.1128/Jvi.29.2.825-827.1979  0.454
1979 Knipe DM, Ruyechan WT, Roizman B. Molecular genetics of herpes simplex virus. III. Fine mapping of a genetic locus determining resistance to phosphonoacetate by two methods of marker transfer Journal of Virology. 29: 698-704. PMID 219255 DOI: 10.1128/Jvi.29.2.698-704.1979  0.533
1979 Ruyechan WT, Morse LS, Knipe DM, Roizman B. Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cells Journal of Virology. 29: 677-697. PMID 219254 DOI: 10.1128/Jvi.29.2.677-697.1979  0.628
1979 Jacob RJ, Morse LS, Roizman B. Anatomy of herpes simplex virus DNA. XII. Accumulation of head-to-tail concatemers in nuclei of infected cells and their role in the generation of the four isomeric arrangements of viral DNA. Journal of Virology. 29: 448-457. PMID 219240 DOI: 10.1128/Jvi.29.2.448-457.1979  0.458
1979 Roizman B, Buchman T. The molecular epidemiology of herpes simplex viruses. Hospital Practice. 14: 95-104. PMID 216624 DOI: 10.1080/21548331.1979.11707470  0.373
1978 Buchman TG, Roizman B, Adams G, Stover BH. Restriction Endonuclease Fingerprinting of Herpes Simplex Virus DNA: A Novel Epidemiological Tool Applied to a Nosocomial Outbreak The Journal of Infectious Diseases. 138: 488-498. PMID 213496 DOI: 10.1093/Infdis/138.4.488  0.391
1978 Knipe DM, Ruyechan WT, Roizman B, Halliburton IW. Molecular genetics of herpes simplex virus: demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion Proceedings of the National Academy of Sciences of the United States of America. 75: 3896-3900. PMID 211508 DOI: 10.1073/Pnas.75.8.3896  0.617
1978 Buchman TG, Roizman B. Anatomy of bovine mammillitis DNA II. Size and arrangements of the deoxynucleotide sequences. Journal of Virology. 27: 239-254. PMID 211253 DOI: 10.1128/Jvi.27.1.239-254.1978  0.317
1978 Morse LS, Pereira L, Roizman B, Schaffer PA. Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants. Journal of Virology. 26: 389-410. PMID 207894 DOI: 10.1128/Jvi.26.2.389-410.1978  0.457
1978 Bartkoski MJ, Roizman B. Regulation of herpesvirus macromolecular synthesis. VII. Inhibition of internal methylation of mRNA late in infection. Virology. 85: 146-156. PMID 205998 DOI: 10.1016/0042-6822(78)90419-1  0.421
1978 Buchman TG, Roizman B. Anatomy of Bovine Mammillitis DNA I. Restriction Endonuclease Maps of Four Populations of Molecules That Differ in the Relative Orientation of Their Long and Short Components Journal of Virology. 25: 395-407. PMID 202750 DOI: 10.1128/Jvi.25.1.395-407.1978  0.33
1977 Morse LS, Buchman TG, Roizman B, Schaffer PA. Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. Journal of Virology. 24: 231-48. PMID 198577 DOI: 10.1128/Jvi.24.1.231-248.1977  0.393
1977 Jacob RJ, Roizman B. Anatomy of Herpes Simplex Virus DNA. VIII. Properties of the Replicating DNA Journal of Virology. 23: 394-411. PMID 196115 DOI: 10.1128/Jvi.23.2.394-411.1977  0.389
1977 Fenwick M, Roizman B. Regulation of herpesvirus macromolecular synthesis. VI. Synthesis and modification of viral polypeptides in enucleated cells. Journal of Virology. 22: 720-725. PMID 195087 DOI: 10.1128/Jvi.22.3.720-725.1977  0.526
1977 Pereira L, Wolff MH, Fenwick M, Roizman B. Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells Virology. 77: 733-749. PMID 193259 DOI: 10.1016/0042-6822(77)90495-0  0.444
1977 Jones PC, Hayward GS, Roizman B. Anatomy of herpes simplex virus DNA. VII. αRNA Is homologous to noncontiguous sites in both the L and S components of viral DNA Journal of Virology. 21: 268-276. PMID 189068 DOI: 10.1128/Jvi.21.1.268-276.1977  0.461
1977 Jones PC, Hayward GS, Roizman B. Anatomy of herpes simplex virus DNA VII. alpha-RNA is homologous to noncontiguous sites in both the L and S components of viral DNA. Journal of Virology. 21: 268-276. DOI: 10.1128/jvi.21.1.268-276.1977  0.326
1976 Bartkoski M, Roizman B. RNA synthesis in cells infected with herpes simple virus. XIII. Differences in the methylation patterns of viral RNA during the reproductive cycle. Journal of Virology. 20: 583-588. PMID 186635 DOI: 10.1128/Jvi.20.3.583-588.1976  0.426
1976 Silvertien S, Millette R, Jones P, Roizman B. RNA synthesis in cells infected with herpes simplex virus. XII. Sequence complexity and properties of RNA differing in extent of adenylation. Journal of Virology. 18: 977-991. PMID 178932 DOI: 10.1128/Jvi.18.3.977-991.1976  0.352
1976 Frenkel N, Locker H, Cox B, Roizman B, Rapp F. Herpes simplex virus DNA in transformed cells: sequence complexity in five hamster cell lines and one derived hamster tumor. Journal of Virology. 18: 885-893. PMID 178927 DOI: 10.1128/Jvi.18.3.885-893.1976  0.413
1976 Pereira L, Cassai E, Honess RW, Roizman B, Terni M, Nahmias A. Variability in the structural polypeptides of herpes simplex virus 1 strains: potential application in molecular epidemiology. Infection and Immunity. 13: 211-220. PMID 175016 DOI: 10.1128/Iai.13.1.211-220.1976  0.328
1976 Hayward GS, Jacob RJ, Wadsworth SC, Roizman B. Anatomy of herpes simplex virus DNA: evidence for four populations of molecules that differ in the relative orientations of their long and short components. Proceedings of the National Academy of Sciences of the United States of America. 72: 4243-7. PMID 172900 DOI: 10.1073/Pnas.72.11.4243  0.395
1976 Frenkeĺ N, Locker H, Batterson W, Hayward GS, Roizman B. Anatomy of herpes simplex virus DNA. VI. Defective DNA originates from the S component. Journal of Virology. 20: 527-531. DOI: 10.1128/Jvi.20.2.527-531.1976  0.387
1976 Wadsworth S, Hayward GS, Roizman B. Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences. Journal of Virology. 17: 503-512. DOI: 10.1128/Jvi.17.2.503-512.1976  0.371
1975 Jacquemont B, Roizman B. Ribonucleic acid synthesis in cells infected with herpes simplex virus: characterization of viral high molecular weight nuclear RNA. Journal of General Virology. 29: 155-165. PMID 213526 DOI: 10.1099/0022-1317-29-2-155  0.396
1975 Honess RW, Roizman B. Proteins specified by herpes simplex virus. XIII. Glycosylation of viral polypeptides. Journal of Virology. 16: 1308-1326. PMID 171454 DOI: 10.1128/Jvi.16.5.1308-1326.1975  0.514
1975 Hayward GS, Frenkel N, Roizman B. Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of restriction endonuclease cleavage sites. Proceedings of the National Academy of Sciences of the United States of America. 72: 1768-72. PMID 168574 DOI: 10.1073/Pnas.72.5.1768  0.406
1975 Wadsworth S, Jacob RJ, Roizman B. Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions. Journal of Virology. 15: 1487-1497. PMID 167196 DOI: 10.1128/Jvi.15.6.1487-1497.1975  0.348
1975 Honess RW, Roizman B. Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 72: 1276-1280. PMID 165503 DOI: 10.1073/Pnas.72.4.1276  0.415
1975 Jacquemont B, Roizman B. RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them. Journal of Virology. 15: 707-713. PMID 163916 DOI: 10.1128/Jvi.15.4.707-713.1975  0.369
1975 Kozak M, Roizman B. RNA synthesis in cells infected with herpes simplex virus. IX. Evidence for accumulation of abundant symmetric transcripts in nuclei. Journal of Virology. 15: 36-40. PMID 163344 DOI: 10.1128/Jvi.15.1.36-40.1975  0.363
1975 Frenkel N, Jacob RJ, Honess RW, Hayward GS, Locker H, Roizman B. Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them. Journal of Virology. 16: 153-167. DOI: 10.1128/Jvi.16.1.153-167.1975  0.468
1974 Kozak M, Roizman B. Regulation of herpesvirus macromolecular synthesis: nuclear retention of nontranslated viral RNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 71: 4322-4326. PMID 4373710 DOI: 10.1073/Pnas.71.11.4322  0.431
1974 Huang AS, Palma EL, Hewlett N, Roizman B. Pseudotype formation between enveloped RNA and DNA viruses. Nature. 252: 743-745. PMID 4373658 DOI: 10.1038/252743A0  0.46
1974 Heine JW, Honess RW, Cassai E, Roizman B. Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. Journal of Virology. 14: 640-651. PMID 4369085 DOI: 10.1128/Jvi.14.3.640-651.1974  0.362
1974 Honess RW, Roizman B. Regulation of Herpesvirus Macromolecular Synthesis I. Cascade Regulation of the Synthesis of Three Groups of Viral Proteins Journal of Virology. 14: 8-19. PMID 4365321 DOI: 10.1128/Jvi.14.1.8-19.1974  0.335
1974 Gibson W, Roizman B. Proteins Specified by Herpes Simplex Virus X. Staining and Radiolabeling Properties of B Capsid and Virion Proteins in Polyacrylamide Gels Journal of Virology. 13: 155-165. PMID 4129836 DOI: 10.1128/Jvi.13.1.155-165.1974  0.65
1974 Roizman B, Kozak M, Honess RW, Hayward G. Regulation of herpesvirus macromolecular synthesis: evidence for multilevel regulation of herpes simplex 1 RNA and protein synthesis. Cold Spring Harbor Symposia On Quantitative Biology. 39: 687-701. PMID 169025 DOI: 10.1101/Sqb.1974.039.01.083  0.34
1973 Honess RW, Roizman B. Proteins Specified by Herpes Simplex Virus XI. Identification and Relative Molar Rates of Synthesis of Structural and Nonstructural Herpes Virus Polypeptides in the Infected Cell Journal of Virology. 12: 1347-1365. PMID 4357511 DOI: 10.1128/Jvi.12.6.1347-1365.1973  0.498
1973 Nahmias AJ, Roizman B. Infection with herpes-simplex viruses 1 and 2. 3. The New England Journal of Medicine. 289: 781-9. PMID 4353941 DOI: 10.1056/nejm197310112891505  0.363
1973 Nahmias AJ, Roizman B. Infection with herpes-simplex viruses 1 and 2. II. The New England Journal of Medicine. 289: 719-725. PMID 4353782 DOI: 10.1056/Nejm197310042891404  0.471
1973 Silverstein S, Bachenheimer SL, Frenkel N, Roizman B. Relationship between post transcriptional adenylation of herpes virus RNA and messenger RNA abundance Proceedings of the National Academy of Sciences of the United States of America. 70: 2101-2104. PMID 4352971 DOI: 10.1073/Pnas.70.7.2101  0.406
1973 Frenkel N, Silverstein S, Cassai E, Roizman B. RNA Synthesis in Cells Infected with Herpes Simplex Virus VII. Control of Transcription and of Transcript Abundancies of Unique and Common Sequences of Herpes Simplex Virus 1 and 2 Journal of Virology. 11: 886-892. PMID 4351458 DOI: 10.1128/Jvi.11.6.886-892.1973  0.454
1973 Heine JW, Roizman B. Proteins Specified by Herpes Simplex Virus IX. Contiguity of Host and Viral Proteins in the Plasma Membrane of Infected Cells Journal of Virology. 11: 810-813. PMID 4122557 DOI: 10.1128/Jvi.11.5.810-813.1973  0.427
1972 Frenkel N, Roizman B, Cassai E, Nahmias A. A DNA Fragment of Herpes Simplex 2 and Its Transcription in Human Cervical Cancer Tissue Proceedings of the National Academy of Sciences of the United States of America. 69: 3784-3789. PMID 4345508 DOI: 10.1073/Pnas.69.12.3784  0.46
1972 Gibson W, Roizman B. Proteins Specified by Herpes Simplex Virus VIII. Characterization and Composition of Multiple Capsid Forms of Subtypes 1 and 2 Journal of Virology. 10: 1044-1052. PMID 4344252 DOI: 10.1128/Jvi.10.5.1044-1052.1972  0.67
1972 Bachenheimer SL, Roizman B. Ribonucleic acid synthesis in cells infected with herpes simplex virus. VI. Polyadenylic acid sequences in viral messenger ribonucleic acid Journal of Virology. 10: 875-879. PMID 4343550 DOI: 10.1128/Jvi.10.4.875-879.1972  0.43
1972 Frenkel N, Roizman B. Separation of the Herpesvirus Deoxyribonucleic Acid Duplex into Unique Fragments and Intact Strand on Sedimentation in Alkaline Gradients Journal of Virology. 10: 565-572. PMID 4343538 DOI: 10.1128/Jvi.10.4.565-572.1972  0.356
1972 Savage T, Roizman B, Heine JW. Immunological Specificity of the Glycoproteins of Herpes Simplex Virus Subtypes 1 and 2 Journal of General Virology. 17: 31-48. PMID 4343529 DOI: 10.1099/0022-1317-17-1-31  0.479
1972 Frenkel N, Roizman B. Ribonucleic acid synthesis in cells infected with herpes simplex virus: controls of transcription and of RNA abundance. Proceedings of the National Academy of Sciences of the United States of America. 69: 2654-2658. PMID 4341703 DOI: 10.1073/Pnas.69.9.2654  0.451
1972 Kieff E, Hoyer B, Bachenheimer S, Roizman B. Genetic relatedness of type 1 and type 2 herpes simplex viruses. Journal of Virology. 9: 738-745. PMID 4337161 DOI: 10.1128/Jvi.9.5.738-745.1972  0.574
1972 Heine JW, Spear PG, Roizman B. Proteins specified by herpes simplex virus. VI. Viral proteins in the plasma membrane. Journal of Virology. 9: 431-9. PMID 4111436 DOI: 10.1128/Jvi.9.3.431-439.1972  0.664
1972 Spear PG, Roizman B. Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpesvirion. Journal of Virology. 9: 143-59. PMID 4110104 DOI: 10.1128/Jvi.9.1.143-159.1972  0.674
1971 Gibson W, Roizman B. Compartmentalization of spermine and spermidine in the herpes simplex virion. Proceedings of the National Academy of Sciences of the United States of America. 68: 2818-2821. PMID 5288261 DOI: 10.1073/Pnas.68.11.2818  0.67
1971 Frenkel N, Roizman B. Herpes Simplex Virus: Genome Size and Redundancy Studied by Renaturation Kinetics Journal of Virology. 8: 591-593. PMID 4331657 DOI: 10.1128/Jvi.8.4.591-593.1971  0.367
1971 Kieff ED, Bachenheimer SL, Roizman B. Size, composition, and structure of the deoxyribonucleic acid of herpes simplex virus subtypes 1 and 2 Journal of Virology. 8: 125-132. PMID 4329966 DOI: 10.1128/Jvi.8.2.125-132.1971  0.587
1971 Roizman B, Spear PG. Herpesvirus antigens on cell membranes detected by centrifugation of membrane-antibody complexes. Science (New York, N.Y.). 171: 298-300. PMID 4321391 DOI: 10.1126/Science.171.3968.298  0.583
1971 Lee LF, Kieff ED, Bachenheimer SL, Roizman B, Spear PG, Burmester BR, Nazerian K. Size and composition of Marek's disease virus deoxyribonucleic acid. Journal of Virology. 7: 289-94. PMID 4101222 DOI: 10.1128/Jvi.7.3.289-294.1971  0.697
1970 Wagner EK, Roizman B, Savage T, Spear PG, Mizell M, Durr FE, Sypowicz D. Characterization of the DNA of herpesviruses associated with Lucké adenocarcinoma of the frog and Burkitt lymphoma of man. Virology. 42: 257-61. PMID 5460136 DOI: 10.1016/0042-6822(70)90265-5  0.539
1970 Morris VL, Wagner EK, Roizman B. RNA Synthesis in cells infected with herpes simplex virus. III. Absence of virus-specified arginyl- and seryl-tRNA in infected HEp-2 cells Journal of Molecular Biology. 52: 247-263. PMID 4320939 DOI: 10.1016/0022-2836(70)90029-X  0.51
1970 Roizman B, Keller JM, Spear PG, Terni M, Nahmias A, Dowdle W. Variability, structural glycoproteins, and classification of herpes simplex viruses. Nature. 227: 1253-4. PMID 4318128 DOI: 10.1038/2271253A0  0.657
1970 Spear PG, Roizman B. Proteins specified by herpes simplex virus, IV. Site of glycosylation and accumulation of viral membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 66: 730-7. PMID 4316680 DOI: 10.1073/Pnas.66.3.730  0.62
1970 Keller JM, Spear PG, Roizman B. Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 65: 865-71. PMID 4314902 DOI: 10.1073/Pnas.65.4.865  0.653
1970 Terni M, Roizman B. Variability of herpes simplex virus: isolation of two variants from simultaneous eruptions at different sites. The Journal of Infectious Diseases. 121: 212-216. PMID 4313188 DOI: 10.1093/Infdis/121.2.212  0.415
1970 Roizman B, Bachenheimer S, Wagner EK, Savage T. Synthesis and Transport of RNA in Herpesvirus-Infected Mammalian Cells Cold Spring Harbor Symposia On Quantitative Biology. 35: 753-771. DOI: 10.1101/Sqb.1970.035.01.091  0.36
1969 Schwartz J, Roizman B. Similarities and Differences in the Development of Laboratory Strains and Freshly Isolated Strains of Herpes Simplex Virus in HEp-2 Cells: Electron Microscopy Journal of Virology. 4: 879-889. PMID 16789121 DOI: 10.1128/Jvi.4.6.879-889.1969  0.371
1969 Roizman B, Spear PG. Macromolecular biosynthesis in animal cells infected with cytolytic viruses. Current Topics in Developmental Biology. 4: 79-108. PMID 4331968 DOI: 10.1016/S0070-2153(08)60481-0  0.665
1969 Lee LF, Roizman B, Spear PG, Kieff ED, Burmester BR, Nazerian K. Marek's disease herpes virus: a cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America. 64: 952-6. PMID 4313336 DOI: 10.1073/Pnas.64.3.952  0.727
1969 Wagner EK, Roizman B. RNA synthesis in cells infected with herpes simplex virus. II. Evidence that a class of viral mRNA is derived from a high molecular weight precursor synthesized in the nucleus Proceedings of the National Academy of Sciences of the United States of America. 64: 626-633. PMID 4311377 DOI: 10.1073/Pnas.64.2.626  0.427
1969 Wagner EK, Roizman B. Ribonucleic acid synthesis in cells infected with herpes simplex virus. I. Patterns of ribonucleic acid synthesis in productively infected cells Journal of Virology. 4: 36-46. PMID 4308689 DOI: 10.1128/Jvi.4.1.36-46.1969  0.419
1969 Spring SB, Roizman B, Spear PG. Selective failure of protein synthesis in herpesvirus-infected cells deprived of arginine. Virology. 38: 710-2. PMID 4308568 DOI: 10.1016/0042-6822(69)90193-7  0.632
1969 Schwartz J, Roizman B. Concerning the egress of herpes simplex virus from infected cells: Electron and light microscope observations Virology. 38: 42-49. PMID 4306525 DOI: 10.1016/0042-6822(69)90126-3  0.486
1968 Spear PG, Roizman B. An improved procedure for H-3 and C-14 counting in acrylamide gels with a nonaqueous scintillation system. Analytical Biochemistry. 26: 197-200. PMID 5758032 DOI: 10.1016/0003-2697(68)90048-1  0.49
1968 Spring SB, Roizman B, Schwartz J. Herpes simplex virus products in productive and abortive infection. II. Electron microscopic and immunological evidence for failure of virus envelopment as a cause of abortive infection Journal of Virology. 2: 384-392. PMID 4316018 DOI: 10.1128/Jvi.2.4.384-392.1968  0.506
1968 Roizman B, Spear PG. Preparation of herpes simplex virus of high titer. Journal of Virology. 2: 83-4. PMID 4316015 DOI: 10.1128/Jvi.2.1.83-84.1968  0.637
1968 Spring SB, Roizman B. Herpes simplex virus products in productive and abortive infection. 3. Differentiation of infectious virus derived from nucleus and cytoplasm with respect to stability and size Journal of Virology. 2: 979-985. PMID 4302014 DOI: 10.1128/Jvi.2.10.979-985.1968  0.511
1968 Spear PG, Roizman B. The proteins specified by herpes simplex virus. I. Time of synthesis, transfer into nuclei, and properties of proteins made in productively infected cells. Virology. 36: 545-55. PMID 4302003 DOI: 10.1016/0042-6822(68)90186-4  0.68
1968 Ejercito PM, Kieff ED, Roizman B. Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells Journal of General Virology. 2: 357-364. PMID 4300104 DOI: 10.1099/0022-1317-2-3-357  0.59
1968 Sydiskis RJ, Roizman B. The sedimentation profiles of cytoplasmic polyribosomes in mammalian cells productively and abortively infected with herpes simplex virus. Virology. 34: 562-565. PMID 4297165 DOI: 10.1016/0042-6822(68)90075-5  0.492
1967 Sydiskis RJ, Roizman B. The disaggregation of host polyribosomes in productive and abortive infection with herpes simplex virus. Virology. 32: 678-686. PMID 18614067 DOI: 10.1016/0042-6822(67)90043-8  0.494
1967 Morris VL, Roizman B. Localization of frog virus multiplication in chick embryo cells by immunofluorescence. Experimental Biology and Medicine. 124: 507-510. PMID 5335650 DOI: 10.3181/00379727-124-31776  0.425
1967 Spring SB, Roizman B. Herpes simplex virus products in productive and abortive infection. I. Stabilization with formaldehyde and preliminary analyses by isopycnic centrifugation in CsCl Journal of Virology. 1: 294-301. PMID 4318948 DOI: 10.1128/Jvi.1.2.294-301.1967  0.394
1967 Spear PG, Roizman B. Buoyant density of herpes simplex virus in solutions of caesium chloride. Nature. 214: 713-4. PMID 4292804 DOI: 10.1038/214713A0  0.613
1967 Roizman B, Spring SB, Roane PR. Cellular compartmentalization of herpesvirus antigens during viral replication Journal of Virology. 1: 181-192. PMID 4195925 DOI: 10.1128/Jvi.1.1.181-192.1967  0.426
1966 Roane PR, Roizman B. Differentiation of nuclear and cytoplasmic herpesvirus antigens in infected cells. Virology. 29: 668-670. PMID 5329568 DOI: 10.1016/0042-6822(66)90290-X  0.398
1966 Morris VL, Spear PG, Roizman B. Some biophysical properties of frog viruses and their DNA. Proceedings of the National Academy of Sciences of the United States of America. 56: 1155-7. PMID 4961525 DOI: 10.1073/Pnas.56.4.1155  0.58
1966 Sydiskis RJ, Roizman B. Polysomes and Protein Synthesis in Cells Infected with a DNA Virus Science. 153: 76-78. PMID 4287165 DOI: 10.1126/Science.153.3731.76  0.518
1965 Borman GS, Roizman B. The inhibition of herpes simplex virus multiplication by nucleosides Bba Section Nucleic Acids and Protein Synthesis. 103: 50-59. PMID 14336442 DOI: 10.1016/0005-2787(65)90540-X  0.476
1965 Roizman B, Borman GS, Rousta MK. Macromolecular synthesis in cells infected with herpes simplex virus [35] Nature. 206: 1374-1375. PMID 4284477 DOI: 10.1038/2061374a0  0.528
1965 Roizman B. Extracellular pH and herpes simplex virus multiplication. Experimental Biology and Medicine. 119: 1021-1023. PMID 4284309 DOI: 10.3181/00379727-119-30365  0.38
1965 Roizman B. Abortive Infection of Canine Cells by Herpes Simplex Virus. III. The Interference, of Conditional Lethal Virus with an Extended Host Range Mutant. Virology. 27: 113-117. PMID 4283989 DOI: 10.1016/0042-6822(65)90148-0  0.5
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