| Year |
Citation |
Score |
| 2024 |
Micchelli CE, Percopo C, Traver M, Brzostowski J, Amin SN, Prigge ST, Sá JM, Wellems TE. Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in persister blood stages after drug treatment. Biorxiv : the Preprint Server For Biology. PMID 38410435 DOI: 10.1101/2024.01.03.574077 |
0.313 |
|
| 2024 |
Hazzard B, Sá J, Bogale H, Pascini T, Ellis A, Amin S, Armistead J, Adams J, Wellems T, Serre D. Single-cell analyses of polyclonal Plasmodium vivax infections and their consequences on parasite transmission. Research Square. PMID 38410426 DOI: 10.21203/rs.3.rs-3888175/v1 |
0.354 |
|
| 2023 |
Abdel Hamid MM, Abdelraheem MH, Acheampong DO, Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amenga-Etego L, Andagalu B, Anderson T, Andrianaranjaka V, Aniebo I, Aninagyei E, Ansah F, ... ... Wellems TE, et al. Pf7: an open dataset of genome variation in 20,000 worldwide samples. Wellcome Open Research. 8: 22. PMID 36864926 DOI: 10.12688/wellcomeopenres.18681.1 |
0.591 |
|
| 2023 |
Singh BK, Zhang C, Wu J, Peng YC, He X, Tumas KC, Sá JM, Lane KD, Eastman RT, Narum DL, Wellems TE, Su XZ. A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses. Antimicrobial Agents and Chemotherapy. e0082122. PMID 36625569 DOI: 10.1128/aac.00821-22 |
0.753 |
|
| 2021 |
Moraes Barros RR, Thawnashom K, Gibson TJ, Armistead JS, Caleon RL, Kaneko M, Kite WA, Mershon JP, Brockhurst JK, Engels T, Lambert L, Orr-Gonzalez S, Adams JH, Sá JM, Kaneko O, ... Wellems TE, et al. Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi, and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle. Malaria Journal. 20: 247. PMID 34090438 DOI: 10.1186/s12936-021-03773-4 |
0.408 |
|
| 2021 |
Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, ... ... Wellems TE, et al. An open dataset of genome variation in 7,000 worldwide samples. Wellcome Open Research. 6: 42. PMID 33824913 DOI: 10.12688/wellcomeopenres.16168.2 |
0.625 |
|
| 2020 |
Ansbro MR, Itkin Z, Chen L, Zahoranszky-Kohalmi G, Amaratunga C, Miotto O, Peryea T, Hobbs CV, Suon S, Sá JM, Dondorp AM, van der Pluijm RW, Wellems TE, Simeonov A, Eastman RT. Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Genotype. Acs Pharmacology & Translational Science. 3: 1144-1157. PMID 33344893 DOI: 10.1021/acsptsci.0c00110 |
0.68 |
|
| 2020 |
Windle ST, Lane KD, Gadalla NB, Liu A, Mu J, Caleon RL, Rahman RS, Sá JM, Wellems TE. Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross. International Journal For Parasitology. Drugs and Drug Resistance. 14: 208-217. PMID 33197753 DOI: 10.1016/j.ijpddr.2020.10.009 |
0.357 |
|
| 2020 |
Wellems TE, Sá JM, Su XZ, Connelly SV, Ellis AC. 'Artemisinin Resistance': Something New or Old? Something of a Misnomer? Trends in Parasitology. PMID 32586776 DOI: 10.1016/J.Pt.2020.05.013 |
0.612 |
|
| 2020 |
Ansbro MR, Jacob CG, Amato R, Kekre M, Amaratunga C, Sreng S, Suon S, Miotto O, Fairhurst RM, Wellems TE, Kwiatkowski DP. Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum. Malaria Journal. 19: 181. PMID 32404110 DOI: 10.1186/s12936-020-03249-x |
0.38 |
|
| 2020 |
Sà JM, Cannon MV, Caleon RL, Wellems TE, Serre D. Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression. Plos Biology. 18: e3000711. PMID 32365102 DOI: 10.1371/journal.pbio.3000711 |
0.364 |
|
| 2019 |
Sá JM, Kaslow SR, Moraes Barros RR, Brazeau NF, Parobek CM, Tao D, Salzman RE, Gibson TJ, Velmurugan S, Krause MA, Melendez-Muniz V, Kite WA, Han PK, Eastman RT, Kim A, ... ... Wellems TE, et al. Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross. Nature Communications. 10: 4300. PMID 31541097 DOI: 10.1038/S41467-019-12256-9 |
0.731 |
|
| 2019 |
Su XZ, Lane KD, Xia L, Sá JM, Wellems TE. Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution. Clinical Microbiology Reviews. 32. PMID 31366610 DOI: 10.1128/Cmr.00019-19 |
0.673 |
|
| 2018 |
Sá JM, Kaslow SR, Krause MA, Melendez-Muniz VA, Salzman RE, Kite WA, Zhang M, Moraes Barros RR, Mu J, Han PK, Mershon JP, Figan CE, Caleon RL, Rahman RS, Gibson TJ, ... ... Wellems TE, et al. Artemisinin resistance phenotypes and K13 inheritance in a cross and model. Proceedings of the National Academy of Sciences of the United States of America. PMID 30455312 DOI: 10.1073/Pnas.1813386115 |
0.731 |
|
| 2018 |
Deng C, Huang B, Wang Q, Wu W, Zheng S, Zhang H, Li D, Feng D, Li G, Xue L, Yang T, Tuo F, Mohadji F, Su XZ, Xu Q, ... ... Wellems TE, et al. Large-scale Artemisinin-Piperaquine Mass Drug Administration With or Without Primaquine Dramatically Reduces Malaria in a Highly Endemic Region of Africa. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29846536 DOI: 10.1093/Cid/Ciy364 |
0.596 |
|
| 2018 |
Lane KD, Mu J, Lu J, Windle ST, Liu A, Sun PD, Wellems TE. Selection of cytochrome B mutants by putative PfNDH2 inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844160 DOI: 10.1073/pnas.1804492115 |
0.333 |
|
| 2018 |
Obaldia N, Meibalan E, Sa JM, Ma S, Clark MA, Mejia P, Moraes Barros RR, Otero W, Ferreira MU, Mitchell JR, Milner DA, Huttenhower C, Wirth DF, Duraisingh MT, Wellems TE, et al. Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection. Mbio. 9. PMID 29739900 DOI: 10.1128/Mbio.00625-18 |
0.304 |
|
| 2018 |
Armistead JS, Moraes Barros RR, Gibson TJ, Kite WA, Patrick Mershon J, Lambert LE, Orr-Gonzalez SE, Sá JM, Adams JH, Wellems TE. Infection of mosquitoes from in vitro cultivated Plasmodium knowlesi H strain. International Journal For Parasitology. PMID 29723510 DOI: 10.1016/J.Ijpara.2018.02.004 |
0.344 |
|
| 2018 |
Figan CE, Sá JM, Mu J, Melendez-Muniz VA, Liu CH, Wellems TE. A set of microsatellite markers to differentiate Plasmodium falciparum progeny of four genetic crosses. Malaria Journal. 17: 60. PMID 29394891 DOI: 10.1186/s12936-018-2210-z |
0.373 |
|
| 2017 |
Barros RRM, Gibson TJ, Kite WA, Sá JM, Wellems TE. Comparison of two methods for transformation of Plasmodium knowlesi: Direct schizont electroporation and spontaneous plasmid uptake from plasmid-loaded red blood cells. Molecular and Biochemical Parasitology. PMID 28988930 DOI: 10.1016/j.molbiopara.2017.10.001 |
0.314 |
|
| 2016 |
Miles A, Iqbal Z, Vauterin P, Pearson R, Campino S, Theron M, Gould K, Mead D, Drury E, O'Brien J, Ruano Rubio V, MacInnis B, Mwangi J, Samarakoon U, Ranford-Cartwright L, ... ... Wellems T, et al. Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum. Genome Research. PMID 27531718 DOI: 10.1101/Gr.203711.115 |
0.649 |
|
| 2016 |
Kite WA, Melendez-Muniz VA, Moraes Barros RR, Wellems TE, Sá JM. Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity. Malaria Journal. 15: 94. PMID 26888201 DOI: 10.1186/s12936-016-1148-2 |
0.313 |
|
| 2015 |
Gadalla NB, Tavera G, Mu J, Kabyemela ER, Fried M, Duffy PE, Sá JM, Wellems TE. Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy. Malaria Journal. 14: 129. PMID 25890383 DOI: 10.1186/S12936-015-0642-2 |
0.302 |
|
| 2015 |
Hayakawa EH, Tokumasu F, Usukura J, Matsuoka H, Tsuboi T, Wellems TE. Imaging of the subsurface structures of "unroofed" Plasmodium falciparum-infected erythrocytes Experimental Parasitology. 153: 174-179. PMID 25825251 DOI: 10.1016/j.exppara.2015.03.021 |
0.358 |
|
| 2015 |
Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, Hamilton E, Ferreira MU, Karunaweera ND, Serre D, Zimmerman PA, Sá JM, Wellems TE, Musset L, Legrand E, et al. Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections. Plos Neglected Tropical Diseases. 9: e0003539. PMID 25781890 DOI: 10.1371/Journal.Pntd.0003539 |
0.351 |
|
| 2015 |
Moraes Barros RR, Straimer J, Sa JM, Salzman RE, Melendez-Muniz VA, Mu J, Fidock DA, Wellems TE. Editing the Plasmodium vivax genome, using zinc-finger nucleases. The Journal of Infectious Diseases. 211: 125-9. PMID 25081932 DOI: 10.1093/Infdis/Jiu423 |
0.378 |
|
| 2013 |
Miller LH, Ackerman HC, Su XZ, Wellems TE. Malaria biology and disease pathogenesis: insights for new treatments. Nature Medicine. 19: 156-67. PMID 23389616 DOI: 10.1038/Nm.3073 |
0.644 |
|
| 2013 |
Hayton K, Dumoulin P, Henschen B, Liu A, Papakrivos J, Wellems TE. Various PfRH5 polymorphisms can support Plasmodium falciparum invasion into the erythrocytes of owl monkeys and rats. Molecular and Biochemical Parasitology. 187: 103-10. PMID 23305874 DOI: 10.1016/j.molbiopara.2012.12.005 |
0.409 |
|
| 2013 |
Kone A, Mu J, Maiga H, Beavogui AH, Yattara O, Sagara I, Tekete MM, Traore OB, Dara A, Dama S, Diallo N, Kodio A, Traoré A, Björkman A, Gil JP, ... ... Wellems TE, et al. Quinine treatment selects the pfnhe-1 ms4760-1 polymorphism in Malian patients with Falciparum malaria. The Journal of Infectious Diseases. 207: 520-7. PMID 23162138 DOI: 10.1093/Infdis/Jis691 |
0.326 |
|
| 2012 |
Papakrivos J, Sá JM, Wellems TE. Functional characterization of the Plasmodium falciparum chloroquine-resistance transporter (PfCRT) in transformed Dictyostelium discoideum vesicles. Plos One. 7: e39569. PMID 22724026 DOI: 10.1371/journal.pone.0039569 |
0.345 |
|
| 2012 |
Lyko B, Hammershaimb EA, Nguitragool W, Wellems TE, Desai SA. A high-throughput method to detect Plasmodium falciparum clones in limiting dilution microplates. Malaria Journal. 11: 124. PMID 22531353 DOI: 10.1186/1475-2875-11-124 |
0.323 |
|
| 2012 |
Wellems TE, Fairhurst RM. An evolving picture of the interactions between malaria parasites and their host erythrocytes. Cell Research. 22: 453-6. PMID 22270182 DOI: 10.1038/cr.2012.14 |
0.375 |
|
| 2011 |
Sá JM, Chong JL, Wellems TE. Malaria drug resistance: new observations and developments. Essays in Biochemistry. 51: 137-60. PMID 22023447 DOI: 10.1042/bse0510137 |
0.324 |
|
| 2011 |
Dondorp AM, Fairhurst RM, Slutsker L, Macarthur JR, Breman JG, Guerin PJ, Wellems TE, Ringwald P, Newman RD, Plowe CV. The threat of artemisinin-resistant malaria. The New England Journal of Medicine. 365: 1073-5. PMID 21992120 DOI: 10.1056/Nejmp1108322 |
0.362 |
|
| 2011 |
Crivat G, Tokumasu F, Sa JM, Hwang J, Wellems TE. Tetracysteine-based fluorescent tags to study protein localization and trafficking in Plasmodium falciparum-infected erythrocytes. Plos One. 6: e22975. PMID 21860664 DOI: 10.1371/journal.pone.0022975 |
0.333 |
|
| 2011 |
Yuan J, Cheng KC, Johnson RL, Huang R, Pattaradilokrat S, Liu A, Guha R, Fidock DA, Inglese J, Wellems TE, Austin CP, Su XZ. Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. Science (New York, N.Y.). 333: 724-9. PMID 21817045 DOI: 10.1126/Science.1205216 |
0.637 |
|
| 2011 |
Jiang H, Li N, Gopalan V, Zilversmit MM, Varma S, Nagarajan V, Li J, Mu J, Hayton K, Henschen B, Yi M, Stephens R, McVean G, Awadalla P, Wellems TE, et al. High recombination rates and hotspots in a Plasmodium falciparum genetic cross. Genome Biology. 12: R33. PMID 21463505 DOI: 10.1186/Gb-2011-12-4-R33 |
0.657 |
|
| 2011 |
Alonso P, Bassat Q, Binka F, Brewer T, Chandra R, Culpepper J, Dinglasan R, Duncan K, Duparc S, Fukuda M, Laxminarayan R, MacArthur, Magill A, Marzetta C, Milman J, ... ... Wellems T, et al. A research agenda for malaria eradication: drugs. Plos Medicine. PMID 21311580 DOI: 10.1371/Journal.Pmed.1000402 |
0.474 |
|
| 2010 |
Mu J, Myers RA, Jiang H, Liu S, Ricklefs S, Waisberg M, Chotivanich K, Wilairatana P, Krudsood S, White NJ, Udomsangpetch R, Cui L, Ho M, Ou F, Li H, ... ... Wellems TE, et al. Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nature Genetics. 42: 268-71. PMID 20101240 DOI: 10.1038/Ng.528 |
0.663 |
|
| 2009 |
Sá JM, Twu O, Hayton K, Reyes S, Fay MP, Ringwald P, Wellems TE. Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine. Proceedings of the National Academy of Sciences of the United States of America. 106: 18883-9. PMID 19884511 DOI: 10.1073/pnas.0911317106 |
0.356 |
|
| 2009 |
Yuan J, Johnson RL, Huang R, Wichterman J, Jiang H, Hayton K, Fidock DA, Wellems TE, Inglese J, Austin CP, Su XZ. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature Chemical Biology. 5: 765-71. PMID 19734910 DOI: 10.1038/Nchembio.215 |
0.626 |
|
| 2009 |
Wellems TE, Hayton K, Fairhurst RM. The impact of malaria parasitism: from corpuscles to communities. The Journal of Clinical Investigation. 119: 2496-505. PMID 19729847 DOI: 10.1172/JCI38307 |
0.42 |
|
| 2008 |
Hayton K, Gaur D, Liu A, Takahashi J, Henschen B, Singh S, Lambert L, Furuya T, Bouttenot R, Doll M, Nawaz F, Mu J, Jiang L, Miller LH, Wellems TE. Erythrocyte binding protein PfRH5 polymorphisms determine species-specific pathways of Plasmodium falciparum invasion. Cell Host & Microbe. 4: 40-51. PMID 18621009 DOI: 10.1016/J.Chom.2008.06.001 |
0.39 |
|
| 2008 |
Cholera R, Brittain NJ, Gillrie MR, Lopera-Mesa TM, Diakité SA, Arie T, Krause MA, Guindo A, Tubman A, Fujioka H, Diallo DA, Doumbo OK, Ho M, Wellems TE, Fairhurst RM. Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 105: 991-6. PMID 18192399 DOI: 10.1073/Pnas.0711401105 |
0.797 |
|
| 2007 |
Su X, Hayton K, Wellems TE. Genetic linkage and association analyses for trait mapping in Plasmodium falciparum. Nature Reviews. Genetics. 8: 497-506. PMID 17572690 DOI: 10.1038/Nrg2126 |
0.648 |
|
| 2007 |
Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, Wellems TE, Su X, Ferdig MT. Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine. Molecular Microbiology. 63: 270-82. PMID 17163969 DOI: 10.1111/J.1365-2958.2006.05511.X |
0.586 |
|
| 2007 |
Brittain NJ, Erexson C, Faucette L, Ward J, Fujioka H, Wellems TE, Fairhurst RM. Non-opsonising aggregates of IgG and complement in haemoglobin C erythrocytes. British Journal of Haematology. 136: 491-500. PMID 17156402 DOI: 10.1111/J.1365-2141.2006.06446.X |
0.755 |
|
| 2006 |
Fairhurst RM, Wellems TE. Modulation of malaria virulence by determinants of Plasmodium falciparum erythrocyte membrane protein-1 display. Current Opinion in Hematology. 13: 124-30. PMID 16567953 DOI: 10.1097/01.moh.0000219655.73162.42 |
0.408 |
|
| 2005 |
Furuya T, Mu J, Hayton K, Liu A, Duan J, Nkrumah L, Joy DA, Fidock DA, Fujioka H, Vaidya AB, Wellems TE, Su XZ. Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 16813-8. PMID 16275909 DOI: 10.1073/Pnas.0501858102 |
0.588 |
|
| 2005 |
Wellems TE, Fairhurst RM. Malaria-protective traits at odds in Africa? Nature Genetics. 37: 1160-2. PMID 16254557 DOI: 10.1038/ng1105-1160 |
0.351 |
|
| 2005 |
Cooper RA, Papakrivos J, Lane KD, Fujioka H, Lingelbach K, Wellems TE. PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites. Molecular and Biochemical Parasitology. 144: 167-76. PMID 16183150 DOI: 10.1016/J.Molbiopara.2005.07.009 |
0.354 |
|
| 2005 |
Fairhurst RM, Baruch DI, Brittain NJ, Ostera GR, Wallach JS, Hoang HL, Hayton K, Guindo A, Makobongo MO, Schwartz OM, Tounkara A, Doumbo OK, Diallo DA, Fujioka H, Ho M, ... Wellems TE, et al. Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria. Nature. 435: 1117-21. PMID 15973412 DOI: 10.1038/Nature03631 |
0.802 |
|
| 2005 |
Naudé B, Brzostowski JA, Kimmel AR, Wellems TE. Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT. The Journal of Biological Chemistry. 280: 25596-603. PMID 15883156 DOI: 10.1074/jbc.M503227200 |
0.308 |
|
| 2005 |
Arie T, Fairhurst RM, Brittain NJ, Wellems TE, Dvorak JA. Hemoglobin C modulates the surface topography of Plasmodium falciparum-infected erythrocytes. Journal of Structural Biology. 150: 163-9. PMID 15866739 DOI: 10.1016/j.jsb.2005.02.008 |
0.798 |
|
| 2005 |
Wang X, Mu J, Li G, Chen P, Guo X, Fu L, Chen L, Su X, Wellems TE. Decreased prevalence of the Plasmodium falciparum chloroquine resistance transporter 76T marker associated with cessation of chloroquine use against P. falciparum malaria in Hainan, People's Republic of China. The American Journal of Tropical Medicine and Hygiene. 72: 410-4. PMID 15827277 |
0.301 |
|
| 2005 |
Tokumasu F, Fairhurst RM, Ostera GR, Brittain NJ, Hwang J, Wellems TE, Dvorak JA. Band 3 modifications in Plasmodium falciparum-infected AA and CC erythrocytes assayed by autocorrelation analysis using quantum dots. Journal of Cell Science. 118: 1091-8. PMID 15731014 DOI: 10.1242/Jcs.01662 |
0.779 |
|
| 2005 |
Wellems TE. Molecular genetics of drug resistance in Plasmodium falciparum malaria. Parasitology Today (Personal Ed.). 7: 110-2. PMID 15463460 DOI: 10.1016/0169-4758(91)90168-N |
0.347 |
|
| 2004 |
Ferdig MT, Cooper RA, Mu J, Deng B, Joy DA, Su XZ, Wellems TE. Dissecting the loci of low-level quinine resistance in malaria parasites. Molecular Microbiology. 52: 985-97. PMID 15130119 DOI: 10.1111/J.1365-2958.2004.04035.X |
0.601 |
|
| 2004 |
Diallo DA, Doumbo OK, Dicko A, Guindo A, Coulibaly D, Kayentao K, Djimdé AA, Théra MA, Fairhurst RM, Plowe CV, Wellems TE. A comparison of anemia in hemoglobin C and normal hemoglobin A children with Plasmodium falciparum malaria. Acta Tropica. 90: 295-9. PMID 15099817 DOI: 10.1016/J.Actatropica.2004.02.005 |
0.348 |
|
| 2003 |
Djimdé AA, Doumbo OK, Traore O, Guindo AB, Kayentao K, Diourte Y, Niare-Doumbo S, Coulibaly D, Kone AK, Cissoko Y, Tekete M, Fofana B, Dicko A, Diallo DA, Wellems TE, et al. Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria. The American Journal of Tropical Medicine and Hygiene. 69: 558-63. PMID 14695097 DOI: 10.4269/Ajtmh.2003.69.558 |
0.422 |
|
| 2003 |
Wellems TE, Miller LH. Two worlds of malaria. The New England Journal of Medicine. 349: 1496-8. PMID 14561790 DOI: 10.1056/NEJMp038127 |
0.363 |
|
| 2003 |
Fairhurst RM, Fujioka H, Hayton K, Collins KF, Wellems TE. Aberrant development of Plasmodium falciparum in hemoglobin CC red cells: implications for the malaria protective effect of the homozygous state. Blood. 101: 3309-15. PMID 12480691 DOI: 10.1182/Blood-2002-10-3105 |
0.406 |
|
| 2003 |
DJIMDÉ AA, DOUMBO OK, NIARE-DOUMBO S, KWIATKOWSKI D, WELLEMS TE, DIOURTE Y, COULIBALY D, DIALLO DA, KAYENTAO K, FOFANA B, TEKETE M, DICKO A, GUINDO AB, PLOWE CV, CISSOKO Y, et al. CLEARANCE OF DRUG-RESISTANT PARASITES AS A MODEL FOR PROTECTIVE IMMUNITY IN PLASMODIUM FALCIPARUM MALARIA The American Journal of Tropical Medicine and Hygiene. 69: 558-563. DOI: 10.4269/ajtmh.2003.69.558 |
0.409 |
|
| 2002 |
Evans AG, Wellems TE. Coevolutionary genetics of Plasmodium malaria parasites and their human hosts. Integrative and Comparative Biology. 42: 401-7. PMID 21708733 DOI: 10.1093/icb/42.2.401 |
0.385 |
|
| 2002 |
Wellems TE. Plasmodium chloroquine resistance and the search for a replacement antimalarial drug. Science (New York, N.Y.). 298: 124-6. PMID 12364789 DOI: 10.1126/science.1078167 |
0.302 |
|
| 2002 |
Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum. Molecular Pharmacology. 61: 35-42. PMID 11752204 DOI: 10.1124/Mol.61.1.35 |
0.607 |
|
| 2001 |
Deitsch KW, Calderwood MS, Wellems TE. Malaria. Cooperative silencing elements in var genes. Nature. 412: 875-6. PMID 11528468 DOI: 10.1038/35091146 |
0.362 |
|
| 2001 |
Wellems TE, Plowe CV. Chloroquine-resistant malaria Journal of Infectious Diseases. 184: 770-776. PMID 11517439 DOI: 10.1086/322858 |
0.361 |
|
| 2001 |
Carlton JM, Fidock DA, Djimdé A, Plowe CV, Wellems TE. Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum. Current Opinion in Microbiology. 4: 415-20. PMID 11495804 DOI: 10.1016/S1369-5274(00)00228-9 |
0.3 |
|
| 2001 |
Kadekoppala M, Cheresh P, Catron D, Ji DD, Deitsch K, Wellems TE, Seifert HS, Haldar K. Rapid recombination among transfected plasmids, chimeric episome formation and trans gene expression in Plasmodium falciparum. Molecular and Biochemical Parasitology. 112: 211-8. PMID 11223128 DOI: 10.1016/S0166-6851(00)00368-6 |
0.377 |
|
| 2001 |
Djimdé A, Doumbo OK, Cortese JF, Kayentao K, Doumbo S, Diourté Y, Coulibaly D, Dicko A, Su XZ, Nomura T, Fidock DA, Wellems TE, Plowe CV. A molecular marker for chloroquine-resistant falciparum malaria. The New England Journal of Medicine. 344: 257-63. PMID 11172152 DOI: 10.1056/Nejm200101253440403 |
0.62 |
|
| 2001 |
Deitsch K, Driskill C, Wellems T. Transformation of malaria parasites by the spontaneous uptake and expression of DNA from human erythrocytes. Nucleic Acids Research. 29: 850-3. PMID 11160909 DOI: 10.1093/Nar/29.3.850 |
0.4 |
|
| 2000 |
Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, Su XZ, Wootton JC, Roepe PD, Wellems TE. Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Molecular Cell. 6: 861-71. PMID 11090624 DOI: 10.1016/S1097-2765(05)00077-8 |
0.587 |
|
| 2000 |
Freitas-Junior LH, Bottius E, Pirrit LA, Deitsch KW, Scheidig C, Guinet F, Nehrbass U, Wellems TE, Scherf A. Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum. Nature. 407: 1018-22. PMID 11069183 DOI: 10.1038/35039531 |
0.393 |
|
| 2000 |
Fidock DA, Nomura T, Cooper RA, Su XZ, Talley AK, Wellems TE. Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum Molecular and Biochemical Parasitology. 110: 1-10. PMID 10989140 DOI: 10.1016/S0166-6851(00)00249-8 |
0.626 |
|
| 2000 |
Taylor JG, Ferdig MT, Su XZ, Wellems TE. Toward quantitative genetic analysis of host and parasite traits in the manifestations of Plasmodium falciparum malaria Current Opinion in Genetics and Development. 10: 314-319. PMID 10826985 DOI: 10.1016/S0959-437X(00)00077-0 |
0.637 |
|
| 2000 |
Agarwal A, Guindo A, Cissoko Y, Taylor JG, Coulibaly D, Koné A, Kayentao K, Djimde A, Plowe CV, Doumbo O, Wellems TE, Diallo D. Hemoglobin C associated with protection from severe malaria in the Dogon of Mali, a West African population with a low prevalence of hemoglobin S Blood. 96: 2358-2363. DOI: 10.1182/blood.V96.7.2358.h8002358_2358_2363 |
0.375 |
|
| 1999 |
Su XZ, Ferdig MT, Huang Y, Huynh CQ, Liu A, You J, Wootton JC, Wellems TE. A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum Science. 286: 1351-1353. PMID 10558988 DOI: 10.1126/Science.286.5443.1351 |
0.599 |
|
| 1999 |
Wellems TE, Su XZ, Ferdig M, Fidock DA. Genome projects, genetic analysis, and the changing landscape of malaria research Current Opinion in Microbiology. 2: 415-419. PMID 10458983 DOI: 10.1016/S1369-5274(99)80073-3 |
0.615 |
|
| 1999 |
Deitsch KW, del Pinal A, Wellems TE. Intra-cluster recombination and var transcription switches in the antigenic variation of Plasmodium falciparum. Molecular and Biochemical Parasitology. 101: 107-16. PMID 10413047 DOI: 10.1016/S1383-5769(98)80107-4 |
0.34 |
|
| 1999 |
Su XZ, Wellems TE. Plasmodium falciparum: assignment of microsatellite markers to chromosomes by PFG-PCR. Experimental Parasitology. 91: 367-9. PMID 10092482 DOI: 10.1006/Expr.1998.4390 |
0.522 |
|
| 1998 |
Fidock DA, Nomura T, Wellems TE. Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase Molecular Pharmacology. 54: 1140-1147. PMID 9855645 DOI: 10.1124/Mol.54.6.1140 |
0.37 |
|
| 1998 |
Wellems TE, Wootton JC, Fujioka H, Su XZ, Cooper R, Baruch D, Fidock DA. P. falciparum CG2, linked to chloroquine resistance, does not resemble Na+/H+ exchangers Cell. 94: 285-286. PMID 9708730 DOI: 10.1016/S0092-8674(00)81471-3 |
0.525 |
|
| 1998 |
Su XZ, Carucci DJ, Wellems TE. Plasmodium falciparum: parasite typing by using a multicopy microsatellite marker, PfRRM. Experimental Parasitology. 89: 262-5. PMID 9635451 DOI: 10.1006/Expr.1998.4299 |
0.596 |
|
| 1998 |
Wellems T, Su X, Fidock D, Nomura T, Cooper R, Baruch D, Fujioka H. A candidate molecule for chloroquine resistance in Plasmodium falciparum malaria Parasitology International. 47: 17. DOI: 10.1016/S1383-5769(98)80009-3 |
0.448 |
|
| 1997 |
Su X, Kirkman LA, Fujioka H, Wellems TE. Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Cell. 91: 593-603. PMID 9393853 DOI: 10.1016/S0092-8674(00)80447-X |
0.624 |
|
| 1997 |
Fidock DA, Wellems TE. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil Proceedings of the National Academy of Sciences of the United States of America. 94: 10931-10936. PMID 9380737 DOI: 10.1073/Pnas.94.20.10931 |
0.399 |
|
| 1997 |
Su XZ, Wellems TE. Plasmodium falciparum: a rapid DNA fingerprinting method using microsatellite sequences within var clusters. Experimental Parasitology. 86: 235-6. PMID 9225776 DOI: 10.1006/Expr.1997.4174 |
0.514 |
|
| 1997 |
Deitsch KW, Wellems TE. Membrane modifications in erythrocytes parasitized by Plasmodium falciparum. Molecular and Biochemical Parasitology. 76: 1-10. PMID 8919990 DOI: 10.1016/0166-6851(95)02575-8 |
0.425 |
|
| 1997 |
Deitsch KW, Moxon ER, Wellems TE. Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections. Microbiology and Molecular Biology Reviews : Mmbr. 61: 281-293. DOI: 10.1128/.61.3.281-293.1997 |
0.308 |
|
| 1996 |
Plowe CV, Wellems TE. Molecular approaches to the spreading problem of drug resistant malaria Advances in Experimental Medicine and Biology. 390: 197-209. PMID 8718614 DOI: 10.1007/978-1-4757-9203-4_17 |
0.379 |
|
| 1996 |
Su Xz, Wellems TE. Toward a high-resolution Plasmodium falciparum linkage map: polymorphic markers from hundreds of simple sequence repeats. Genomics. 33: 430-44. PMID 8661002 DOI: 10.1006/Geno.1996.0218 |
0.58 |
|
| 1996 |
Kirkman LA, Su XZ, Wellems TE. Plasmodium falciparum: isolation of large numbers of parasite clones from infected blood samples. Experimental Parasitology. 83: 147-9. PMID 8654543 DOI: 10.1006/Expr.1996.0058 |
0.598 |
|
| 1996 |
Su XZ, Wu Y, Sifri CD, Wellems TE. Reduced extension temperatures required for PCR amplification of extremely A+T-rich DNA. Nucleic Acids Research. 24: 1574-5. PMID 8628694 DOI: 10.1093/Nar/24.8.1574 |
0.49 |
|
| 1996 |
Wu Y, Kirkman LA, Wellems TE. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proceedings of the National Academy of Sciences of the United States of America. 93: 1130-4. PMID 8577727 DOI: 10.1073/pnas.93.3.1130 |
0.379 |
|
| 1996 |
Waters AF, Wirth DF, Wellems TE, Del Portllo HA. Transfection of malaria parasites Parasitology Today. 12: 129-132. DOI: 10.1016/0169-4758(96)30002-1 |
0.426 |
|
| 1995 |
Wu Y, Sifri CD, Lei HH, Su XZ, Wellems TE. Transfection of Plasmodium falciparum within human red blood cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 973-7. PMID 7862676 DOI: 10.1073/Pnas.92.4.973 |
0.637 |
|
| 1995 |
Su XZ, Wellems TE. Sequence, transcript characterization and polymorphisms of a Plasmodium falciparum gene belonging to the heat-shock protein (HSP) 90 family. Gene. 151: 225-30. PMID 7828879 DOI: 10.1016/0378-1119(94)90661-0 |
0.541 |
|
| 1995 |
Vaidya AB, Muratova O, Guinet F, Keister D, Wellems TE, Kaslow DC. A genetic locus on Plasmodium falciparum chromosome 12 linked to a defect in mosquito-infectivity and male gametogenesis Molecular and Biochemical Parasitology. 69: 65-71. PMID 7723789 DOI: 10.1016/0166-6851(94)00199-W |
0.355 |
|
| 1995 |
Plowe CV, Djimde A, Bouare M, Doumbo O, Wellems TE. Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa. The American Journal of Tropical Medicine and Hygiene. 52: 565-8. PMID 7611566 DOI: 10.4269/Ajtmh.1995.52.565 |
0.364 |
|
| 1995 |
Su XZ, Heatwole VM, Wertheimer SP, Guinet F, Herrfeldt JA, Peterson DS, Ravetch JA, Wellems TE. The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell. 82: 89-100. PMID 7606788 DOI: 10.1016/0092-8674(95)90055-1 |
0.311 |
|
| 1992 |
Krogstad DJ, Gluzman IY, Herwaldt BL, Schlesinger PH, Wellems TE. Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum Biochemical Pharmacology. 43: 57-62. PMID 1531176 DOI: 10.1016/0006-2952(92)90661-2 |
0.384 |
|
| 1992 |
Smith O, Dolan S, Dvorak J, Wellems T, Sieber F. Merocyanine 540-sensitized photoinactivation of human erythrocytes parasitized by Plasmodium falciparum Blood. 80: 21-24. DOI: 10.1182/blood.v80.1.21.21 |
0.366 |
|
| 1991 |
Wellems TE, Walker-Jonah A, Panton LJ. Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. Proceedings of the National Academy of Sciences of the United States of America. 88: 3382-6. PMID 1673031 DOI: 10.1073/pnas.88.8.3382 |
0.343 |
|
| 1990 |
Dolan SA, Miller LH, Wellems TE. Evidence for a switching mechanism in the invasion of erythrocytes by Plasmodium falciparum. The Journal of Clinical Investigation. 86: 618-24. PMID 2200806 DOI: 10.1172/JCI114753 |
0.319 |
|
| 1990 |
Peterson DS, Milhous WK, Wellems TE. Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. Proceedings of the National Academy of Sciences of the United States of America. 87: 3018-22. PMID 2183222 DOI: 10.1073/pnas.87.8.3018 |
0.407 |
|
| 1990 |
Wellems TE, Panton LJ, Gluzman IY, Do Rosario VE, Gwadz RW, Walker-Jonah A, Krogstad DJ. Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross Nature. 345: 253-255. PMID 1970614 |
0.335 |
|
| 1988 |
Rock EP, Marsh K, Saul AJ, Wellems TE, Taylor DW, Maloy WL, Howard RJ. Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin. Parasitology. 209-27. PMID 3320887 DOI: 10.1017/S0031182000057681 |
0.306 |
|
| 1988 |
Peterson DS, Walliker D, Wellems TE. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proceedings of the National Academy of Sciences of the United States of America. 85: 9114-8. PMID 2904149 DOI: 10.1073/Pnas.85.23.9114 |
0.304 |
|
| 1987 |
Walliker D, Quakyi IA, Wellems TE, McCutchan TF, Szarfman A, London WT, Corcoran LM, Burkot TR, Carter R. Genetic analysis of the human malaria parasite Plasmodium falciparum. Science (New York, N.Y.). 236: 1661-6. PMID 3299700 DOI: 10.1126/Science.3299700 |
0.451 |
|
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