| Year |
Citation |
Score |
| 2023 |
Chen Y, Liang R, Shi X, Shen R, Liu L, Liu Y, Xue Y, Guo X, Dang J, Zeng D, Huang F, Sun J, Zhang J, Wang J, Olsen N, ... August A, et al. Targeting kinase ITK treats autoimmune arthritis via orchestrating T cell differentiation and function. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 169: 115886. PMID 37992572 DOI: 10.1016/j.biopha.2023.115886 |
0.418 |
|
| 2023 |
August A. Degrading the signal amplifier: ITK as a target for targeted protein degradation. Cell Chemical Biology. 30: 337-339. PMID 37084715 DOI: 10.1016/j.chembiol.2023.04.001 |
0.35 |
|
| 2023 |
Anannya O, Huang W, August A. ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway. Biorxiv : the Preprint Server For Biology. PMID 37066370 DOI: 10.1101/2023.04.01.535229 |
0.483 |
|
| 2022 |
McGee MC, August A, Huang W. High-Efficiency Retroviral Transduction for Type 1 Regulatory T Cell Differentiation. Bio-Protocol. 12. PMID 36245799 DOI: 10.21769/BioProtoc.4499 |
0.439 |
|
| 2022 |
Chen W, Huang W, Xue Y, Chen Y, Qian W, Ma J, August A, Wang J, Zheng SG, Lin J. Neuropilin-1 Identifies a New Subpopulation of TGF-β-Induced Foxp3 Regulatory T Cells With Potent Suppressive Function and Enhanced Stability During Inflammation. Frontiers in Immunology. 13: 900139. PMID 35603221 DOI: 10.3389/fimmu.2022.900139 |
0.401 |
|
| 2022 |
Elmore J, Carter C, Redko A, Koylass N, Bennett A, Mead M, Ocasio-Rivera M, Huang W, Singh A, August A. ITK independent development of Th17 responses during hypersensitivity pneumonitis driven lung inflammation. Communications Biology. 5: 162. PMID 35210549 DOI: 10.1038/s42003-022-03109-1 |
0.439 |
|
| 2022 |
Mammadli M, Harris R, Suo L, May A, Gentile T, Waickman AT, Bah A, August A, Nurmemmedov E, Karimi M. Interleukin-2-inducible T-cell kinase (Itk) signaling regulates potent noncanonical regulatory T cells. Clinical and Translational Medicine. 11: e625. PMID 34919342 DOI: 10.1002/ctm2.625 |
0.497 |
|
| 2021 |
Sahler J, Anannya O, Limper C, Imbiakha B, Pierpont T, August A. Genetic Analysis of iNKT Cell Development and Function. Methods in Molecular Biology (Clifton, N.J.). 2388: 1-12. PMID 34524657 DOI: 10.1007/978-1-0716-1775-5_1 |
0.367 |
|
| 2021 |
Mammadli M, Harris R, Mahmudlu S, Verma A, May A, Dhawan R, Waickman AT, Sen JM, August A, Karimi M. Human Wnt/β-Catenin Regulates Alloimmune Signaling during Allogeneic Transplantation. Cancers. 13. PMID 34359702 DOI: 10.3390/cancers13153798 |
0.337 |
|
| 2021 |
Lechner K, Mott S, Al-Saifi R, Knipfer L, Wirtz S, Atreya R, Vieth M, Rath T, Fraass T, Winter Z, August A, Luban J, Zimmermann VS, Weigmann B, Neurath MF. Targeting of the Tec kinase ITK drives resolution of T cell-mediated colitis and emerges as potential therapeutic option in ulcerative colitis. Gastroenterology. PMID 34224738 DOI: 10.1053/j.gastro.2021.06.072 |
0.427 |
|
| 2021 |
Mammadli M, Huang W, Harris R, Xiong H, Weeks S, May A, Gentile T, Henty-Ridilla J, Waickman AT, August A, Bah A, Karimi M. Targeting SLP76:ITK interaction separates GVHD from GVL in allo-HSCT. Iscience. 24: 102286. PMID 33851101 DOI: 10.1016/j.isci.2021.102286 |
0.357 |
|
| 2021 |
Torres L, Redko A, Limper C, Imbiakha B, Chang S, August A. Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice. Immunology Letters. PMID 33722553 DOI: 10.1016/j.imlet.2021.03.006 |
0.302 |
|
| 2021 |
McGee MC, August A, Huang W. TCR/ITK Signaling in Type 1 Regulatory T cells. Advances in Experimental Medicine and Biology. 1278: 115-124. PMID 33523446 DOI: 10.1007/978-981-15-6407-9_7 |
0.487 |
|
| 2020 |
Mammadli M, Huang W, Harris R, Sultana A, Cheng Y, Tong W, Pu J, Gentile T, Dsouza S, Yang Q, Bah A, August A, Karimi M. Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT. Frontiers in Immunology. 11: 593863. PMID 33324410 DOI: 10.3389/fimmu.2020.593863 |
0.423 |
|
| 2020 |
Solouki S, Huang W, Elmore J, Limper C, Huang F, August A. TCR Signal Strength and Antigen Affinity Regulate CD8 Memory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32759295 DOI: 10.4049/Jimmunol.1901167 |
0.489 |
|
| 2020 |
McGee MC, August A, Huang W. BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID-19 therapy. Journal of Leukocyte Biology. PMID 32640487 DOI: 10.1002/Jlb.5Covr0620-306R |
0.475 |
|
| 2020 |
Huang W, Solouki S, Koylass N, Zheng SG, August A. Author Correction: ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells. Nature Communications. 11: 2579. PMID 32427893 DOI: 10.1038/S41467-020-16420-4 |
0.33 |
|
| 2020 |
Elmore JP, McGee MC, Nidetz NF, Anannya O, Huang W, August A. Tuning T helper cell differentiation by ITK. Biochemical Society Transactions. PMID 32049330 DOI: 10.1042/Bst20190486 |
0.585 |
|
| 2019 |
Huang L, Ye K, McGee MC, Nidetz NF, Elmore JP, Limper CB, Southard TL, Russell DG, August A, Huang W. Interleukin-2-Inducible T-Cell Kinase Deficiency Impairs Early Pulmonary Protection Against Infection. Frontiers in Immunology. 10: 3103. PMID 32038633 DOI: 10.3389/Fimmu.2019.03103 |
0.56 |
|
| 2019 |
Afroz S, Shama, Battu S, Matin S, Solouki S, Elmore JP, Minhas G, Huang W, August A, Khan N. Amino acid starvation enhances vaccine efficacy by augmenting neutralizing antibody production. Science Signaling. 12. PMID 31719173 DOI: 10.1126/Scisignal.Aav4717 |
0.325 |
|
| 2019 |
Solouki S, August A, Huang W. Non-receptor tyrosine kinase signaling in autoimmunity and therapeutic implications. Pharmacology & Therapeutics. PMID 31082431 DOI: 10.1016/J.Pharmthera.2019.05.008 |
0.49 |
|
| 2019 |
Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, ... ... August A, et al. Thymic regulatory T cells arise via two distinct developmental programs. Nature Immunology. PMID 30643267 DOI: 10.1038/S41590-018-0289-6 |
0.502 |
|
| 2018 |
Huang W, Solouki S, Carter C, Zheng SG, August A. Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages. Frontiers in Immunology. 9: 2625. PMID 30510554 DOI: 10.3389/Fimmu.2018.02625 |
0.534 |
|
| 2018 |
Purwada A, Shah SB, Béguelin W, August A, Melnick AM, Singh A. Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells. Biomaterials. PMID 30041943 DOI: 10.1016/J.Biomaterials.2018.06.034 |
0.364 |
|
| 2018 |
August A. Who regulates whom: ZNF341 is an additional player in the STAT3/T17 song. Science Immunology. 3. PMID 29907692 DOI: 10.1126/Sciimmunol.Aat9779 |
0.422 |
|
| 2018 |
Battu S, Afroz S, Giddaluru J, Naz S, Huang W, Khumukcham SS, Khan RA, Bhat S, Qureshi IA, Manavathi B, Khan AA, August A, Hasnain SE, Khan N. Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy. Plos Biology. 16: e2005317. PMID 29621237 DOI: 10.1371/Journal.Pbio.2005317 |
0.366 |
|
| 2017 |
Pabon J, Law MK, August A. Drebrin Regulation of Calcium Signaling in Immune Cells. Advances in Experimental Medicine and Biology. 1006: 281-290. PMID 28865026 DOI: 10.1007/978-4-431-56550-5_16 |
0.362 |
|
| 2017 |
Huang W, Solouki S, Koylass N, Zheng SG, August A. ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells. Nature Communications. 8: 15871. PMID 28635957 DOI: 10.1038/Ncomms15871 |
0.53 |
|
| 2017 |
Kannan AK, Mohinta S, Huang W, Huang L, Koylass N, Appleton JA, August A. T-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk. Scientific Reports. 7: 45935. PMID 28406139 DOI: 10.1038/Srep45935 |
0.545 |
|
| 2016 |
Ganguly K, Giddaluru J, August A, Khan N. Post-transcriptional Regulation of Immunological Responses through Riboclustering. Frontiers in Immunology. 7: 161. PMID 27199986 DOI: 10.3389/Fimmu.2016.00161 |
0.314 |
|
| 2016 |
Huang W, August A. Role(s) of IL-2 inducible T cell kinase and Bruton's tyrosine kinase in mast cell response to lipopolysaccharide. Genomics Data. 8: 18-20. PMID 27081634 DOI: 10.1016/J.Gdata.2016.02.010 |
0.532 |
|
| 2016 |
Huang W, August A. Role(s) of IL-2 inducible T cell kinase and Bruton's tyrosine kinase in mast cell response to lipopolysaccharide Genomics Data. 8: 18-20. DOI: 10.1016/j.gdata.2016.02.010 |
0.447 |
|
| 2015 |
Huang W, Morales JL, Gazivoda VP, August A. Nonreceptor tyrosine kinases ITK and BTK negatively regulate mast cell proinflammatory responses to lipopolysaccharide. The Journal of Allergy and Clinical Immunology. PMID 26581914 DOI: 10.1016/J.Jaci.2015.08.056 |
0.438 |
|
| 2015 |
Law M, Lee Y, Morales JL, Ning G, Huang W, Pabon J, Kannan AK, Jeong AR, Wood A, Carter C, Mohinta S, Song J, August A. Cutting Edge: Drebrin-Regulated Actin Dynamics Regulate IgE-Dependent Mast Cell Activation and Allergic Responses. Journal of Immunology (Baltimore, Md. : 1950). 195: 426-30. PMID 26056254 DOI: 10.4049/Jimmunol.1401442 |
0.802 |
|
| 2015 |
Kannan A, Lee Y, Qi Q, Huang W, Jeong AR, Ohnigian S, August A. Allele-sensitive mutant, Itkas, reveals that Itk kinase activity is required for Th1, Th2, Th17, and iNKT-cell cytokine production. European Journal of Immunology. 45: 2276-85. PMID 25989458 DOI: 10.1002/Eji.201445087 |
0.732 |
|
| 2015 |
Balmus G, Lim PX, Oswald A, Hume KR, Cassano A, Pierre J, Hill A, Huang W, August A, Stokol T, Southard T, Weiss RS. HUS1 regulates in vivo responses to genotoxic chemotherapies. Oncogene. PMID 25915840 DOI: 10.1038/Onc.2015.118 |
0.362 |
|
| 2015 |
Mohinta S, Kannan AK, Gowda K, Amin SG, Perdew GH, August A. Differential regulation of Th17 and T regulatory cell differentiation by aryl hydrocarbon receptor dependent xenobiotic response element dependent and independent pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 145: 233-43. PMID 25716673 DOI: 10.1093/Toxsci/Kfv046 |
0.416 |
|
| 2015 |
Stokes K, LaMarche NM, Islam N, Wood A, Huang W, August A. Cutting edge: STAT6 signaling in eosinophils is necessary for development of allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2477-81. PMID 25681342 DOI: 10.4049/Jimmunol.1402096 |
0.471 |
|
| 2015 |
Kannan AK, Kim DG, August A, Bynoe MS. Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 221-33. PMID 25568116 DOI: 10.1523/Jneurosci.1957-14.2015 |
0.521 |
|
| 2015 |
Huang F, Huang W, Briggs J, Chew T, Bai Y, Deol S, August A. The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection. Scientific Reports. 5: 7688. PMID 25567129 DOI: 10.1038/Srep07688 |
0.479 |
|
| 2015 |
Huang W, August A. The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation. Journal of Leukocyte Biology. 97: 477-85. PMID 25525115 DOI: 10.1189/Jlb.1Ri0614-293R |
0.554 |
|
| 2014 |
Huang W, Jeong AR, Kannan AK, Huang L, August A. IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function. Journal of Immunology (Baltimore, Md. : 1950). 193: 2267-72. PMID 25063868 DOI: 10.4049/Jimmunol.1400968 |
0.572 |
|
| 2014 |
Huang W, Huang F, Kannan AK, Hu J, August A. ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner. Journal of Leukocyte Biology. 96: 55-63. PMID 24620029 DOI: 10.1189/Jlb.1Ab0913-484Rr |
0.752 |
|
| 2014 |
Huang W, Qi Q, Hu J, Huang F, Laufer TM, August A. Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation. Journal of Immunology (Baltimore, Md. : 1950). 192: 3435-41. PMID 24610010 DOI: 10.4049/Jimmunol.1303176 |
0.821 |
|
| 2013 |
Kudva AK, Kaushal N, Mohinta S, Kennett MJ, August A, Paulson RF, Prabhu KS. Evaluation of the stability, bioavailability, and hypersensitivity of the omega-3 derived anti-leukemic prostaglandin: Δ(12)-prostaglandin J3. Plos One. 8: e80622. PMID 24312486 DOI: 10.1371/Journal.Pone.0080622 |
0.334 |
|
| 2013 |
Huang W, August A. Editorial: Jack of all trades? The versatility of IL-4 in CD8+ T cell polarity. Journal of Leukocyte Biology. 94: 1097-9. PMID 24296591 DOI: 10.1189/Jlb.0513271 |
0.499 |
|
| 2013 |
Kannan AK, Sahu N, Mohanan S, Mohinta S, August A. IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells. The Journal of Allergy and Clinical Immunology. 132: 811-20.e1-5. PMID 23768572 DOI: 10.1016/J.Jaci.2013.04.033 |
0.842 |
|
| 2013 |
Huang W, Morales JL, Gazivoda VP, Lai J, Qi Q, August A. The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with Gα13 and activation of serum response factor. The International Journal of Biochemistry & Cell Biology. 45: 1074-82. PMID 23454662 DOI: 10.1016/J.Biocel.2013.02.011 |
0.733 |
|
| 2013 |
Huang W, Hu J, August A. Cutting edge: innate memory CD8+ T cells are distinct from homeostatic expanded CD8+ T cells and rapidly respond to primary antigenic stimuli. Journal of Immunology (Baltimore, Md. : 1950). 190: 2490-4. PMID 23408840 DOI: 10.4049/Jimmunol.1202988 |
0.735 |
|
| 2012 |
Kannan A, Huang W, Huang F, August A. Signal transduction via the T cell antigen receptor in naïve and effector/memory T cells. The International Journal of Biochemistry & Cell Biology. 44: 2129-34. PMID 22981631 DOI: 10.1016/J.Biocel.2012.08.023 |
0.515 |
|
| 2012 |
August A, Ragin MJ. Regulation of T-cell responses and disease by tec kinase Itk. International Reviews of Immunology. 31: 155-65. PMID 22449075 DOI: 10.3109/08830185.2012.668981 |
0.845 |
|
| 2012 |
Qi Q, Huang W, Bai Y, Balmus G, Weiss RS, August A. A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 3611-9. PMID 22403441 DOI: 10.4049/Jimmunol.1102475 |
0.72 |
|
| 2011 |
Qi Q, Kannan AK, August A. Structure and function of Tec family kinase Itk. Biomolecular Concepts. 2: 223-32. PMID 25962031 DOI: 10.1515/Bmc.2011.020 |
0.752 |
|
| 2011 |
Law M, Morales JL, Mottram LF, Iyer A, Peterson BR, August A. Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2. The International Journal of Biochemistry & Cell Biology. 43: 1228-39. PMID 21558014 DOI: 10.1016/J.Biocel.2011.04.016 |
0.808 |
|
| 2011 |
Qi Q, Kannan AK, August A. Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells. The Febs Journal. 278: 1970-9. PMID 21362141 DOI: 10.1111/J.1742-4658.2011.08074.X |
0.757 |
|
| 2011 |
Walsh ER, Thakar J, Stokes K, Huang F, Albert R, August A. Computational and experimental analysis reveals a requirement for eosinophil-derived IL-13 for the development of allergic airway responses in C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 2936-49. PMID 21289305 DOI: 10.4049/Jimmunol.1001148 |
0.46 |
|
| 2011 |
Iyer AS, Morales JL, Huang W, Ojo F, Ning G, Wills E, Baines JD, August A. Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses. The Journal of Biological Chemistry. 286: 9503-13. PMID 21212279 DOI: 10.1074/Jbc.M110.165613 |
0.783 |
|
| 2011 |
Qi Q, Xia M, Bai Y, Yu S, Cantorna M, August A. Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell. The Journal of Biological Chemistry. 286: 138-46. PMID 21036902 DOI: 10.1074/Jbc.M110.148205 |
0.753 |
|
| 2010 |
Sahu N, Morales JL, Fowell D, August A. Modeling susceptibility versus resistance in allergic airway disease reveals regulation by Tec kinase Itk. Plos One. 5: e11348. PMID 20596543 DOI: 10.1371/Journal.Pone.0011348 |
0.764 |
|
| 2010 |
Xia M, Qi Q, Jin Y, Wiest DL, August A, Xiong N. Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 6807-14. PMID 20483745 DOI: 10.4049/Jimmunol.1000453 |
0.728 |
|
| 2010 |
Natarajan M, August A, Henderson AJ. Combinatorial signals from CD28 differentially regulate human immunodeficiency virus transcription in T cells. The Journal of Biological Chemistry. 285: 17338-47. PMID 20368329 DOI: 10.1074/Jbc.M109.085324 |
0.38 |
|
| 2010 |
Khanna P, Yunkunis T, Muddana HS, Peng HH, August A, Dong C. p38 MAP kinase is necessary for melanoma-mediated regulation of VE-cadherin disassembly. American Journal of Physiology. Cell Physiology. 298: C1140-50. PMID 20181932 DOI: 10.1152/Ajpcell.00242.2009 |
0.422 |
|
| 2010 |
Hu J, Qi Q, August A. Itk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells. Plos One. 5: e8891. PMID 20126642 DOI: 10.1371/Journal.Pone.0008891 |
0.805 |
|
| 2010 |
He S, Ni S, Hegde S, Wang X, Sharda DR, August A, Paulson RF, Hankey PA. Activation of the N-terminally truncated form of the Stk receptor tyrosine kinase Sf-Stk by Friend virus-encoded gp55 is mediated by cysteine residues in the ecotropic domain of gp55 and the extracellular domain of Sf-Stk. Journal of Virology. 84: 2223-35. PMID 20016000 DOI: 10.1128/Jvi.02090-09 |
0.359 |
|
| 2010 |
Mercer JC, Qi Q, Mottram LF, Law M, Bruce D, Iyer A, Morales JL, Yamazaki H, Shirao T, Peterson BR, August A. Chemico-genetic identification of drebrin as a regulator of calcium responses. The International Journal of Biochemistry & Cell Biology. 42: 337-45. PMID 19948240 DOI: 10.1016/J.Biocel.2009.11.019 |
0.747 |
|
| 2010 |
Walsh ER, August A. Eosinophils and allergic airway disease: there is more to the story. Trends in Immunology. 31: 39-44. PMID 19926338 DOI: 10.1016/J.It.2009.10.001 |
0.485 |
|
| 2009 |
Gomez-Rodriguez J, Sahu N, Handon R, Davidson TS, Anderson SM, Kirby MR, August A, Schwartzberg PL. Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity. 31: 587-97. PMID 19818650 DOI: 10.1016/J.Immuni.2009.07.009 |
0.825 |
|
| 2009 |
Qi Q, August A. The Tec family kinase Itk exists as a folded monomer in vivo. The Journal of Biological Chemistry. 284: 29882-92. PMID 19717557 DOI: 10.1074/Jbc.M109.003129 |
0.644 |
|
| 2009 |
Sahu N, August A. ITK inhibitors in inflammation and immune-mediated disorders. Current Topics in Medicinal Chemistry. 9: 690-703. PMID 19689375 DOI: 10.2174/156802609789044443 |
0.844 |
|
| 2009 |
August A. IL-2-inducible T-cell kinase (ITK) finds another (dance) partner...TFII-I. European Journal of Immunology. 39: 2354-7. PMID 19688746 DOI: 10.1002/Eji.200939813 |
0.568 |
|
| 2009 |
Qi Q, Xia M, Hu J, Hicks E, Iyer A, Xiong N, August A. Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production. Blood. 114: 564-71. PMID 19443662 DOI: 10.1182/Blood-2008-12-196345 |
0.841 |
|
| 2009 |
Soni S, Lin BT, August A, Nicholson RI, Kirsch KH. Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells. Journal of Cellular Biochemistry. 107: 364-75. PMID 19330798 DOI: 10.1002/Jcb.22136 |
0.338 |
|
| 2009 |
Bruce D, Whitcomb JP, August A, McDowell MA, Cantorna MT. Elevated non-specific immunity and normal Listeria clearance in young and old vitamin D receptor knockout mice. International Immunology. 21: 113-22. PMID 19088060 DOI: 10.1093/Intimm/Dxn129 |
0.337 |
|
| 2008 |
Sahu N, Venegas AM, Jankovic D, Mitzner W, Gomez-Rodriguez J, Cannons JL, Sommers C, Love P, Sher A, Schwartzberg PL, August A. Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 181: 6125-31. PMID 18941202 DOI: 10.4049/Jimmunol.181.9.6125 |
0.81 |
|
| 2008 |
Strasner AB, Natarajan M, Doman T, Key D, August A, Henderson AJ. The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane. Journal of Immunology (Baltimore, Md. : 1950). 181: 3706-13. PMID 18714047 DOI: 10.4049/Jimmunol.181.5.3706 |
0.324 |
|
| 2008 |
Iyer AS, August A. The Tec family kinase, IL-2-inducible T cell kinase, differentially controls mast cell responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 7869-77. PMID 18523250 DOI: 10.4049/Jimmunol.180.12.7869 |
0.778 |
|
| 2008 |
Walsh ER, Sahu N, Kearley J, Benjamin E, Kang BH, Humbles A, August A. Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma. The Journal of Experimental Medicine. 205: 1285-92. PMID 18490489 DOI: 10.1084/Jem.20071836 |
0.795 |
|
| 2008 |
Hu J, August A. Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development. Journal of Immunology (Baltimore, Md. : 1950). 180: 6544-52. PMID 18453573 DOI: 10.4049/Jimmunol.180.10.6544 |
0.739 |
|
| 2008 |
Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Selective targeting of ITK blocks multiple steps of HIV replication. Proceedings of the National Academy of Sciences of the United States of America. 105: 6684-9. PMID 18443296 DOI: 10.1073/Pnas.0709659105 |
0.343 |
|
| 2008 |
Sahu N, Mueller C, Fischer A, August A. Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration. Journal of Immunology (Baltimore, Md. : 1950). 180: 3833-8. PMID 18322190 DOI: 10.4049/Jimmunol.180.6.3833 |
0.831 |
|
| 2007 |
Hu J, Sahu N, Walsh E, August A. Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk. European Journal of Immunology. 37: 2892-9. PMID 17724684 DOI: 10.1002/Eji.200737311 |
0.845 |
|
| 2007 |
Qi Q, August A. Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe39. PMID 17652306 DOI: 10.1126/Stke.3962007Pe39 |
0.744 |
|
| 2007 |
Wittke A, Chang A, Froicu M, Harandi OF, Weaver V, August A, Paulson RF, Cantorna MT. Vitamin D receptor expression by the lung micro-environment is required for maximal induction of lung inflammation. Archives of Biochemistry and Biophysics. 460: 306-13. PMID 17224129 DOI: 10.1016/J.Abb.2006.12.011 |
0.359 |
|
| 2007 |
Boonyarattanakalin S, Hu J, Dykstra-Rummel SA, August A, Peterson BR. Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo. Journal of the American Chemical Society. 129: 268-9. PMID 17212394 DOI: 10.1021/Ja067674F |
0.653 |
|
| 2007 |
Walsh E, Sahu N, August A. Eosinophils are Required for T Cell Infiltration of Lungs During Allergic Asthma Responses Journal of Allergy and Clinical Immunology. 119: S153. DOI: 10.1016/J.Jaci.2006.11.534 |
0.786 |
|
| 2006 |
Qi Q, Sahu N, August A. Tec kinase Itk forms membrane clusters specifically in the vicinity of recruiting receptors. The Journal of Biological Chemistry. 281: 38529-34. PMID 17060314 DOI: 10.1074/Jbc.M609180200 |
0.808 |
|
| 2006 |
Hao S, Qi Q, Hu J, August A. A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation. Febs Letters. 580: 2691-7. PMID 16631752 DOI: 10.1016/J.Febslet.2006.04.023 |
0.809 |
|
| 2006 |
Ferrara TJ, Mueller C, Sahu N, Ben-Jebria A, August A. Reduced airway hyperresponsiveness and tracheal responses during allergic asthma in mice lacking tyrosine kinase inducible T-cell kinase. The Journal of Allergy and Clinical Immunology. 117: 780-6. PMID 16630934 DOI: 10.1016/J.Jaci.2005.12.1330 |
0.814 |
|
| 2006 |
August A, Mueller C, Weaver V, Polanco TA, Walsh ER, Cantorna MT. Nutrients, nuclear receptors, inflammation, immunity lipids, PPAR, and allergic asthma. The Journal of Nutrition. 136: 695-9. PMID 16484545 DOI: 10.1093/Jn/136.3.695 |
0.506 |
|
| 2006 |
Ragin MJ, Sahu N, August A. Differential regulation of cytokine production by CD1d-restricted NKT cells in response to superantigen staphylococcal enterotoxin B exposure. Infection and Immunity. 74: 282-8. PMID 16368982 DOI: 10.1128/Iai.74.1.282-288.2006 |
0.822 |
|
| 2005 |
Ragin MJ, Hu J, Henderson AJ, August A. A role for the Tec family kinase ITK in regulating SEB-induced interleukin-2 production in vivo via c-jun phosphorylation. Bmc Immunology. 6: 19. PMID 16042784 DOI: 10.1186/1471-2172-6-19 |
0.808 |
|
| 2005 |
Mercer JC, Ragin MJ, August A. Natural killer T cells: rapid responders controlling immunity and disease. The International Journal of Biochemistry & Cell Biology. 37: 1337-43. PMID 15833265 DOI: 10.1016/J.Biocel.2004.11.019 |
0.834 |
|
| 2005 |
Hao S, August A. Actin depolymerization transduces the strength of B-cell receptor stimulation. Molecular Biology of the Cell. 16: 2275-84. PMID 15728723 DOI: 10.1091/Mbc.E04-10-0881 |
0.78 |
|
| 2004 |
Ferrara TJ, August A, Ben-Jebria A. Modulation of tracheal smooth muscle responses in inducible T-cell kinase knockout mice. Pulmonary Pharmacology & Therapeutics. 17: 301-8. PMID 15477126 DOI: 10.1016/J.Pupt.2004.07.002 |
0.45 |
|
| 2004 |
Wittke A, Weaver V, Mahon BD, August A, Cantorna MT. Vitamin D receptor-deficient mice fail to develop experimental allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 173: 3432-6. PMID 15322208 DOI: 10.4049/Jimmunol.173.5.3432 |
0.339 |
|
| 2004 |
Fischer AM, Mercer JC, Iyer A, Ragin MJ, August A. Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK. The Journal of Biological Chemistry. 279: 29816-20. PMID 15123627 DOI: 10.1074/Jbc.M312848200 |
0.825 |
|
| 2003 |
Mueller C, Weaver V, Vanden Heuvel JP, August A, Cantorna MT. Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. Archives of Biochemistry and Biophysics. 418: 186-96. PMID 14522590 DOI: 10.1016/J.Abb.2003.08.006 |
0.466 |
|
| 2003 |
Hao S, Kurosaki T, August A. Differential regulation of NFAT and SRF by the B cell receptor via a PLCgamma-Ca(2+)-dependent pathway. The Embo Journal. 22: 4166-77. PMID 12912915 DOI: 10.1093/Emboj/Cdg401 |
0.791 |
|
| 2003 |
Cook JA, Albacker L, August A, Henderson AJ. CD28-dependent HIV-1 transcription is associated with Vav, Rac, and NF-kappa B activation. The Journal of Biological Chemistry. 278: 35812-8. PMID 12842899 DOI: 10.1074/Jbc.M302878200 |
0.425 |
|
| 2003 |
Mueller C, August A. Attenuation of immunological symptoms of allergic asthma in mice lacking the tyrosine kinase ITK. Journal of Immunology (Baltimore, Md. : 1950). 170: 5056-63. PMID 12734350 DOI: 10.4049/Jimmunol.170.10.5056 |
0.538 |
|
| 2002 |
Hao S, August A. hCMV IE Promoter is responsive to B cell receptor signaling in a Bruton's tyrosine kinase dependent manner: caution in their use as internal controls. Analytical Biochemistry. 309: 315-7. PMID 12413466 DOI: 10.1016/S0003-2697(02)00299-3 |
0.8 |
|
| 2002 |
Hao S, August A. The proline rich region of the Tec homology domain of ITK regulates its activity. Febs Letters. 525: 53-8. PMID 12163161 DOI: 10.1016/S0014-5793(02)03066-1 |
0.823 |
|
| 2002 |
August A, Fischer A, Hao S, Mueller C, Ragin M. The Tec family of tyrosine kinases in T cells, amplifiers of T cell receptor signals. The International Journal of Biochemistry & Cell Biology. 34: 1184-9. PMID 12127569 DOI: 10.1016/S1357-2725(02)00068-7 |
0.824 |
|
| 2002 |
Kirsch K, Kensinger M, Hanafusa H, August A. A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling. Bmc Cell Biology. 3: 18. PMID 12119061 DOI: 10.1186/1471-2121-3-18 |
0.381 |
|
| 2002 |
Cook JA, August A, Henderson AJ. Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 169: 254-60. PMID 12077252 DOI: 10.4049/Jimmunol.169.1.254 |
0.445 |
|
| 2002 |
Tao L, Wadsworth S, Mercer J, Mueller C, Lynn K, Siekierka J, August A. Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells. The Biochemical Journal. 363: 175-82. PMID 11903060 DOI: 10.1042/0264-6021:3630175 |
0.531 |
|
| 2001 |
Woods ML, Kivens WJ, Adelsman MA, Qiu Y, August A, Shimizu Y. A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor. The Embo Journal. 20: 1232-44. PMID 11250890 DOI: 10.1093/Emboj/20.6.1232 |
0.455 |
|
| 1997 |
August A, Sadra A, Dupont B, Hanafusa H. Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 11227-32. PMID 9326591 DOI: 10.1073/Pnas.94.21.11227 |
0.628 |
|
| 1997 |
Teng JM, King PD, Sadra A, Liu X, Han A, Selvakumar A, August A, Dupont B. Phosphorylation of each of the distal three tyrosines of the CD28 cytoplasmic tail is required for CD28-induced T cell IL-2 secretion. Tissue Antigens. 48: 255-64. PMID 8946678 DOI: 10.1111/j.1399-0039.1996.tb02643.x |
0.605 |
|
| 1996 |
Gibson S, August A, Branch D, Dupont B, Mills GB. Functional LCK is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK Journal of Biological Chemistry. 271: 7079-7083. PMID 8636141 DOI: 10.1074/Jbc.271.12.7079 |
0.605 |
|
| 1996 |
August A, Dupont B. Association between mitogen-activated protein kinase and the ζ chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck: Differential regulation by TcR cross-linking Journal of Biological Chemistry. 271: 10054-10059. PMID 8626561 DOI: 10.1074/jbc.271.17.10054 |
0.61 |
|
| 1995 |
August A, Dupont B. Activation of extracellular signal-regulated protein kinase (ERK/MAP kinase) following CD28 cross-linking: Activation in cells lacking p56(lck) Tissue Antigens. 46: 155-162. PMID 8525474 DOI: 10.1111/j.1399-0039.1995.tb03114.x |
0.643 |
|
| 1994 |
August A, Dupont B. Activation of src family kinase lck following CD28 crosslinking in the Jurkat leukemic cell line Biochemical and Biophysical Research Communications. 199: 1466-1473. PMID 8147892 DOI: 10.1006/bbrc.1994.1396 |
0.586 |
|
| 1994 |
August A, Dupont B. CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase International Immunology. 6: 769-774. PMID 8080844 DOI: 10.1093/intimm/6.5.769 |
0.639 |
|
| 1994 |
August A, Gibson S, Kawakami Y, Kawakami T, Mills GB, Dupont B. CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line. Proceedings of the National Academy of Sciences of the United States of America. 91: 9347-51. PMID 7524075 DOI: 10.1073/Pnas.91.20.9347 |
0.679 |
|
| 1994 |
August A, Dupont B. Triggering of the CD3 complex on T cells results in the recruitment of the guanine nucleotide exchange factor p95vav and the ZAP-70 tyrosine kinase Human Immunology. 40: 22. DOI: 10.1016/0198-8859(94)91703-5 |
0.604 |
|
| 1994 |
August A, Gibson S, Kawakami Y, Kawakami T, Mills G, Dupont B. Tyrosine phosphorylation and activation of the tec family kinase member emt/itk/tsk following CD28 and CD3 crosslinking Human Immunology. 40: 5. DOI: 10.1016/0198-8859(94)91669-1 |
0.524 |
|
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