| Year |
Citation |
Score |
| 2019 |
Ozten N, Vega K, Liehr J, Huang X, Horton L, Cavalieri EL, Rogan EG, Bosland MC. Role of Estrogen in Androgen-Induced Prostate Carcinogenesis in NBL Rats. Hormones & Cancer. PMID 30877616 DOI: 10.1007/S12672-019-00360-7 |
0.303 |
|
| 2005 |
Markides CS, Liehr JG. Specific binding of 4-hydroxyestradiol to mouse uterine protein: evidence of a physiological role for 4-hydroxyestradiol. The Journal of Endocrinology. 185: 235-42. PMID 15845916 DOI: 10.1677/joe.1.06014 |
0.634 |
|
| 2001 |
Liehr JG, Jones JS. Role of iron in estrogen-induced cancer. Current Medicinal Chemistry. 8: 839-49. PMID 11375754 |
0.556 |
|
| 2000 |
Cavalieri E, Frenkel K, Liehr JG, Rogan E, Roy D. Estrogens as endogenous genotoxic agents--DNA adducts and mutations. Journal of the National Cancer Institute. Monographs. 75-93. PMID 10963621 DOI: 10.1093/Oxfordjournals.Jncimonographs.A024247 |
0.391 |
|
| 1999 |
Sarabia SF, Liehr JG. Differential regulation of c-fos expression in estrogen-induced hamster renal tumors compared with kidney not due to creation of an estrogen-response element by point mutation in the gene's flanking sequence. Molecular Carcinogenesis. 24: 255-62. PMID 10326862 DOI: 10.1002/(Sici)1098-2744(199904)24:4<255::Aid-Mc3>3.0.Co;2-C |
0.322 |
|
| 1999 |
Roy D, Liehr JG. Estrogen, DNA damage and mutations. Mutation Research. 424: 107-15. PMID 10064854 DOI: 10.1016/S0027-5107(99)00012-3 |
0.351 |
|
| 1998 |
Paria BC, Lim H, Wang XN, Liehr J, Das SK, Dey SK. Coordination of Differential Effects of Primary Estrogen and Catecholestrogen on Two Distinct Targets Mediates Embryo Implantation in the Mouse* * This work was supported, in part, by NIH Grant HD-12304 and as part of the National Cooperative Program on Markers of Uterine Receptivity for Blastocyst Implantation [NIH Grants HD-29968 (to S.K.D.), HD-35114 (to B.C.P.), and ES-07814 (to S.K.D.)]. A center grant in Reproductive Biology (HD-33994) and a center grant in Mental Retardation and Developmental Disabilities (HD-02528) provided access to various core facilities. Endocrinology. 139: 5235-5246. PMID 28200406 DOI: 10.1210/Endo.139.12.6386 |
0.314 |
|
| 1998 |
Liehr JG, Roy D. Pro-oxidant and antioxidant effects of estrogens. Methods in Molecular Biology (Clifton, N.J.). 108: 425-35. PMID 9921549 DOI: 10.1385/0-89603-472-0:425 |
0.322 |
|
| 1998 |
Markides CS, Roy D, Liehr JG. Concentration dependence of prooxidant and antioxidant properties of catecholestrogens. Archives of Biochemistry and Biophysics. 360: 105-12. PMID 9826435 DOI: 10.1006/Abbi.1998.0934 |
0.639 |
|
| 1998 |
Sarabia SF, Liehr JG. Induction of monoamine oxidase B by 17 beta-estradiol in the hamster kidney preceding carcinogenesis. Archives of Biochemistry and Biophysics. 355: 249-53. PMID 9675034 DOI: 10.1006/Abbi.1998.0727 |
0.381 |
|
| 1998 |
Liehr JG. Catecholestrogens in the induction of tumors in the kidney of the Syrian hamster. Advances in Pharmacology (San Diego, Calif.). 42: 824-8. PMID 9328024 DOI: 10.1016/S1054-3589(08)60873-X |
0.413 |
|
| 1997 |
Wyllie S, Liehr JG. Release of iron from ferritin storage by redox cycling of stilbene and steroid estrogen metabolites: a mechanism of induction of free radical damage by estrogen. Archives of Biochemistry and Biophysics. 346: 180-6. PMID 9343364 DOI: 10.1006/Abbi.1997.0306 |
0.347 |
|
| 1997 |
Sarabia SF, Zhu BT, Kurosawa T, Tohma M, Liehr JG. Mechanism of cytochrome P450-catalyzed aromatic hydroxylation of estrogens. Chemical Research in Toxicology. 10: 767-71. PMID 9250410 DOI: 10.1021/Tx970021F |
0.361 |
|
| 1997 |
Hammond DK, Zhu BT, Wang MY, Ricci MJ, Liehr JG. Cytochrome P450 metabolism of estradiol in hamster liver and kidney. Toxicology and Applied Pharmacology. 145: 54-60. PMID 9221823 DOI: 10.1006/Taap.1997.8167 |
0.355 |
|
| 1997 |
Liehr JG. Hormone-associated cancer: mechanistic similarities between human breast cancer and estrogen-induced kidney carcinogenesis in hamsters. Environmental Health Perspectives. 105: 565-9. PMID 9167996 DOI: 10.1289/Ehp.97105S3565 |
0.361 |
|
| 1996 |
Ahmed AE, Jacob S, Giovanella BC, Kozielski AJ, Stehlin JS, Liehr JG. Influence of route of administration on [3H]-camptothecin distribution and tumor uptake in CASE-bearing nude mice: whole-body autoradiographic studies. Cancer Chemotherapy and Pharmacology. 39: 122-30. PMID 8995509 DOI: 10.1007/S002800050547 |
0.3 |
|
| 1996 |
Liehr JG, Ricci MJ. 4-Hydroxylation of estrogens as marker of human mammary tumors. Proceedings of the National Academy of Sciences of the United States of America. 93: 3294-6. PMID 8622931 DOI: 10.1073/Pnas.93.8.3294 |
0.328 |
|
| 1996 |
Winter ML, Liehr JG. Possible mechanism of induction of benign prostatic hyperplasia by estradiol and dihydrotestosterone in dogs. Toxicology and Applied Pharmacology. 136: 211-9. PMID 8619228 DOI: 10.1006/Taap.1996.0027 |
0.302 |
|
| 1996 |
Zhu BT, Liehr JG. Inhibition of catechol O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by quercetin. Possible role in estradiol-induced tumorigenesis. The Journal of Biological Chemistry. 271: 1357-63. PMID 8576124 DOI: 10.1074/Jbc.271.3.1357 |
0.31 |
|
| 1996 |
Zhu BT, Evaristus EN, Antoniak SK, Sarabia SF, Ricci MJ, Liehr JG. Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis. Toxicology and Applied Pharmacology. 136: 186-93. PMID 8560473 DOI: 10.1006/Taap.1996.0023 |
0.38 |
|
| 1995 |
Wang MY, Liehr JG. Lipid hydroperoxide-induced endogenous DNA adducts in hamsters: possible mechanism of lipid hydroperoxide-mediated carcinogenesis. Archives of Biochemistry and Biophysics. 316: 38-46. PMID 7840640 DOI: 10.1006/Abbi.1995.1007 |
0.344 |
|
| 1995 |
Han X, Liehr JG, Bosland MC. Induction of a DNA adduct detectable by 32P-postlabeling in the dorsolateral prostate of NBL/Cr rats treated with estradiol-17 beta and testosterone. Carcinogenesis. 16: 951-4. PMID 7728979 DOI: 10.1093/Carcin/16.4.951 |
0.309 |
|
| 1995 |
Moorthy B, Liehr J, Randerath E, Randerath K. Evidence from 32P-postlabeling and the use of pentachlorophenol for a novel metabolic activation pathway of diethylstilbestrol and its dimethyl ether in mouse live: likely alpha-hydroxylation of ethyl group(s) followed by sulfate conjugation. Carcinogenesis. 16: 2643-8. PMID 7586180 DOI: 10.1093/Carcin/16.11.2643 |
0.372 |
|
| 1995 |
Han X, Liehr JG. Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones. Carcinogenesis. 16: 2571-4. PMID 7586168 DOI: 10.1093/Carcin/16.10.2571 |
0.415 |
|
| 1995 |
Liehr JG, Ricci MJ, Jefcoate CR, Hannigan EV, Hokanson JA, Zhu BT. 4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: implications for the mechanism of uterine tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 92: 9220-4. PMID 7568105 DOI: 10.1073/Pnas.92.20.9220 |
0.387 |
|
| 1995 |
Li D, Wang M, Liehr JG, Randerath K. DNA adducts induced by lipids and lipid peroxidation products: possible relationships to I-compounds. Mutation Research. 344: 117-26. PMID 7491129 DOI: 10.1016/0165-1218(95)90001-2 |
0.361 |
|
| 1994 |
Zhu BT, Liehr JG. Quercetin increases the severity of estradiol-induced tumorigenesis in hamster kidney. Toxicology and Applied Pharmacology. 125: 149-58. PMID 8128490 DOI: 10.1006/Taap.1994.1059 |
0.399 |
|
| 1994 |
Zhu BT, Bui QD, Weisz J, Liehr JG. Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis. Endocrinology. 135: 1772-9. PMID 7956900 DOI: 10.1210/Endo.135.5.7956900 |
0.351 |
|
| 1994 |
Bhat HK, Han X, Gladek A, Liehr JG. Regulation of the formation of the major diethylstilbestrol-DNA adduct and some evidence of its structure. Carcinogenesis. 15: 2137-42. PMID 7955045 DOI: 10.1093/Carcin/15.10.2137 |
0.365 |
|
| 1993 |
Ashburn SP, Han X, Liehr JG. Microsomal hydroxylation of 2- and 4-fluoroestradiol to catechol metabolites and their conversion to methyl ethers: catechol estrogens as possible mediators of hormonal carcinogenesis. Molecular Pharmacology. 43: 534-41. PMID 8386306 |
0.302 |
|
| 1993 |
Zhu BT, Roy D, Liehr JG. The carcinogenic activity of ethinyl estrogens is determined by both their hormonal characteristics and their conversion to catechol metabolites. Endocrinology. 132: 577-83. PMID 8381068 DOI: 10.1210/Endo.132.2.8381068 |
0.425 |
|
| 1993 |
Zhu BT, Liehr JG. Inhibition of the catechol-O-methyltransferase-catalyzed O-methylation of 2- and 4-hydroxyestradiol by catecholamine: implications for the mechanism of estrogen-induced carcinogenesis. Archives of Biochemistry and Biophysics. 304: 248-56. PMID 8323288 DOI: 10.1006/Abbi.1993.1346 |
0.329 |
|
| 1993 |
Purewal M, Liehr JG. Covalent modification of DNA by daunorubicin. Cancer Chemotherapy and Pharmacology. 33: 239-44. PMID 8269605 DOI: 10.1007/Bf00686222 |
0.328 |
|
| 1992 |
Roy D, Bernhardt A, Strobel HW, Liehr JG. Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the beta-naphthoflavone-inducible cytochrome P450 IA family. Archives of Biochemistry and Biophysics. 296: 450-6. PMID 1632637 DOI: 10.1016/0003-9861(92)90596-O |
0.37 |
|
| 1992 |
Liehr JG, Folse DS, Roy D. Lack of effectiveness of antiestrogens RU 39,411 or keoxifene in the prevention of estrogen-induced tumors in Syrian hamsters. Cancer Letters. 64: 23-9. PMID 1596873 DOI: 10.1016/0304-3835(92)90017-P |
0.323 |
|
| 1992 |
Liehr JG, Chiappetta C, Roy D, Stancel GM. Elevation of protooncogene messenger RNAs in estrogen-induced kidney tumors in the hamster Carcinogenesis. 13: 601-604. PMID 1576713 DOI: 10.1093/Carcin/13.4.601 |
0.31 |
|
| 1992 |
Weisz J, Bui QD, Roy D, Liehr JG. Elevated 4-hydroxylation of estradiol by hamster kidney microsomes: a potential pathway of metabolic activation of estrogens. Endocrinology. 131: 655-61. PMID 1386303 DOI: 10.1210/Endo.131.2.1386303 |
0.354 |
|
| 1992 |
Roy D, Liehr JG. Target organ-specific inactivation of drug metabolizing enzymes in kidney of hamsters treated with estradiol. Molecular and Cellular Biochemistry. 110: 31-9. PMID 1315925 DOI: 10.1007/Bf02385003 |
0.397 |
|
| 1991 |
Gladek A, Liehr JG. Transplacental genotoxicity of diethylstilbestrol. Carcinogenesis. 12: 773-6. PMID 2029740 DOI: 10.1093/Carcin/12.5.773 |
0.339 |
|
| 1991 |
Liehr JG, Gladek A, Macatee T, Randerath E, Randerath K. DNA adduct formation in liver and kidney of male Syrian hamsters treated with estrogen and/or alpha-naphthoflavone. Carcinogenesis. 12: 385-9. PMID 2009585 DOI: 10.1093/Carcin/12.3.385 |
0.372 |
|
| 1991 |
Roy D, Hachey DL, Liehr JG. Determination of estradiol 2- and 4-hydroxylase activities by gas chromatography with electron-capture detection. Journal of Chromatography. 567: 309-18. PMID 1939464 DOI: 10.1016/0378-4347(91)80137-2 |
0.311 |
|
| 1991 |
Roy D, Kalyanaraman B, Liehr JG. Xanthine oxidase-catalyzed reduction of estrogen quinones to semiquinones and hydroquinones. Biochemical Pharmacology. 42: 1627-31. PMID 1656992 DOI: 10.1016/0006-2952(91)90433-6 |
0.33 |
|
| 1990 |
Roy D, Weisz J, Liehr JG. The O-methylation of 4-hydroxyestradiol is inhibited by 2-hydroxyestradiol: implications for estrogen-induced carcinogenesis. Carcinogenesis. 11: 459-62. PMID 2311190 DOI: 10.1093/Carcin/11.3.459 |
0.333 |
|
| 1990 |
Liehr JG, Roy D. Free radical generation by redox cycling of estrogens. Free Radical Biology & Medicine. 8: 415-23. PMID 2199344 DOI: 10.1016/0891-5849(90)90108-U |
0.431 |
|
| 1990 |
Liehr JG, Roy D, Ari-Ulubelen A, Bui QD, Weisz J, Strobel HW. Effect of chronic estrogen treatment of Syrian hamsters on microsomal enzymes mediating formation of catecholestrogens and their redox cycling: implications for carcinogenesis. Journal of Steroid Biochemistry. 35: 555-60. PMID 2162450 DOI: 10.1016/0022-4731(90)90198-2 |
0.399 |
|
| 1990 |
Liehr JG. Genotoxic effects of estrogens. Mutation Research. 238: 269-76. PMID 2160607 DOI: 10.1016/0165-1110(90)90018-7 |
0.439 |
|
| 1990 |
Roy D, Liehr JG. Inhibition of estrogen-induced kidney carcinogenesis in Syrian hamsters by modulators of estrogen metabolism. Carcinogenesis. 11: 567-70. PMID 1691052 DOI: 10.1093/Carcin/11.4.567 |
0.4 |
|
| 1989 |
Randerath K, Liehr JG, Gladek A, Randerath E. Age-dependent covalent DNA alterations (I-compounds) in rodent tissues: species, tissue and sex specificities. Mutation Research. 219: 121-33. PMID 2927417 DOI: 10.1016/0921-8734(89)90023-4 |
0.332 |
|
| 1989 |
Roy D, Liehr JG. Metabolic oxidation of diethylstilbestrol to diethylstilbestrol-4',4"-quinone in Syrian hamsters. Carcinogenesis. 10: 1241-5. PMID 2736717 DOI: 10.1093/Carcin/10.7.1241 |
0.358 |
|
| 1989 |
Liehr JG, Roy D, Gladek A. Mechanism of inhibition of estrogen-induced renal carcinogenesis in male Syrian hamsters by vitamin C. Carcinogenesis. 10: 1983-8. PMID 2572356 DOI: 10.1093/Carcin/10.11.1983 |
0.365 |
|
| 1989 |
Roy D, Bui QD, Weisz J, Liehr JG. Comparison of assays for catechol estrogen synthase activity: product isolation vs radioenzymatic catechol-O-methyltransferase-coupled procedures. Journal of Steroid Biochemistry. 33: 243-9. PMID 2549304 DOI: 10.1016/0022-4731(89)90300-2 |
0.318 |
|
| 1988 |
Lu LJ, Liehr JG, Sirbasku DA, Randerath E, Randerath K. Hypomethylation of DNA in estrogen-induced and -dependent hamster kidney tumors. Carcinogenesis. 9: 925-9. PMID 3370756 DOI: 10.1093/Carcin/9.6.925 |
0.366 |
|
| 1986 |
Valette A, Meignen JM, Mercier L, Liehr JG, Boyer J. Effects of 2-fluoroestradiol on lipid metabolism in the ovariectomized rat. Journal of Steroid Biochemistry. 25: 575-8. PMID 3773528 DOI: 10.1016/0022-4731(86)90405-X |
0.316 |
|
| 1986 |
Liehr JG, Avitts TA, Randerath E, Randerath K. Estrogen-induced endogenous DNA adduction: possible mechanism of hormonal cancer. Proceedings of the National Academy of Sciences of the United States of America. 83: 5301-5. PMID 3460092 DOI: 10.1073/Pnas.83.14.5301 |
0.401 |
|
| 1986 |
Liehr JG, Wan-Fen F, Sirbasku DA, Ari-Ulubelen A. Carcinogenicity of catechol estrogens in Syrian hamsters Journal of Steroid Biochemistry. 24: 353-356. PMID 3009986 DOI: 10.1016/0022-4731(86)90080-4 |
0.372 |
|
| 1986 |
Liehr JG, Ballatore AM, Dague BB, Ulubelen AA. Carcinogenicity and metabolic activation of hexestrol. Chemico-Biological Interactions. 55: 157-76. PMID 2998630 DOI: 10.1016/S0009-2797(85)80125-3 |
0.379 |
|
| 1985 |
Liehr JG, DaGue BB, Ballatore AM. Reactivity of 4',4"-diethylstilbestrol quinone, a metabolic intermediate of diethylstilbestrol. Carcinogenesis. 6: 829-36. PMID 4006069 DOI: 10.1093/Carcin/6.6.829 |
0.379 |
|
| 1984 |
Liehr JG, DaGue BB, Ballatore AM, Henkin J. Diethylstilbestrol (DES) quinone: a reactive intermediate in DES metabolism. Biochemical Pharmacology. 32: 3711-8. PMID 6661246 DOI: 10.1016/0006-2952(83)90139-9 |
0.36 |
|
| 1984 |
Liehr JG. Modulation of estrogen-induced carcinogenesis by chemical modifications. Archives of Toxicology. 55: 119-22. PMID 6477124 DOI: 10.1007/Bf00346049 |
0.389 |
|
| 1982 |
Holmes PF, Liehr JG, Henkin J. Synthesis and characterization of 2′-azidoaminopterin as a potential photoaffinity label for folate-utilizing enzymes☆ Bioorganic Chemistry. 11: 281-299. DOI: 10.1016/0045-2068(82)90004-9 |
0.303 |
|
| Show low-probability matches. |