| Year |
Citation |
Score |
| 2023 |
Sohn JH, Mutlu B, Latorre-Muro P, Liang J, Bennett CF, Sharabi K, Kantorovich N, Jedrychowski M, Gygi SP, Banks AS, Puigserver P. Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism. Cell Metabolism. PMID 37473754 DOI: 10.1016/j.cmet.2023.06.015 |
0.325 |
|
| 2023 |
Yook JS, Taxin ZH, Yuan B, Oikawa S, Auger C, Mutlu B, Puigserver P, Hui S, Kajimura S. The SLC25A47 locus controls gluconeogenesis and energy expenditure. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216810120. PMID 36812201 DOI: 10.1073/pnas.2216810120 |
0.61 |
|
| 2021 |
Bennett CF, O'Malley KE, Perry EA, Balsa E, Latorre-Muro P, Riley CL, Luo C, Jedrychowski M, Gygi SP, Puigserver P. Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Nature Chemical Biology. PMID 33723432 DOI: 10.1038/s41589-021-00772-z |
0.698 |
|
| 2020 |
Tavares CDJ, Aigner S, Sharabi K, Sathe S, Mutlu B, Yeo GW, Puigserver P. Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action. Proceedings of the National Academy of Sciences of the United States of America. PMID 32848060 DOI: 10.1073/Pnas.2000643117 |
0.38 |
|
| 2020 |
Mutlu B, Puigserver P. GCN5 ACETYLTRANSFERASE IN CELLULAR ENERGETIC AND METABOLIC PROCESSES. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194626. PMID 32827753 DOI: 10.1016/J.Bbagrm.2020.194626 |
0.438 |
|
| 2020 |
Luo C, Liang J, Sharabi K, Hatting M, Perry EA, Tavares CD, Goyal L, Srivastava A, Bilodeau M, Zhu AX, Sicinski P, Puigserver P. Obesity/type 2 diabetes-associated liver tumors are sensitive to Cyclin D1 deficiency. Cancer Research. PMID 32606000 DOI: 10.1158/0008-5472.Can-20-0106 |
0.3 |
|
| 2020 |
Balsa E, Perry EA, Bennett CF, Jedrychowski M, Gygi SP, Doench JG, Puigserver P. Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death. Nature Communications. 11: 2714. PMID 32483148 DOI: 10.1038/S41467-020-16423-1 |
0.37 |
|
| 2020 |
Luo C, Balsa E, Perry EA, Liang J, Tavares CD, Vazquez F, Widlund HR, Puigserver P. H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP. The Journal of Clinical Investigation. PMID 31929186 DOI: 10.1172/Jci130038 |
0.373 |
|
| 2020 |
Cruces-Sande M, Arcones AC, Vila-Bedmar R, Val-Blasco A, Sharabi K, Díaz-Rodríguez D, Puigserver P, Mayor F, Murga C. Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 399-409. PMID 31914606 DOI: 10.1096/Fj.201901444R |
0.439 |
|
| 2019 |
Sharabi K, Tavares CDJ, Puigserver P. Regulation of Hepatic Metabolism, Recent Advances, and Future Perspectives. Current Diabetes Reports. 19: 98. PMID 31494755 DOI: 10.1007/S11892-019-1224-4 |
0.379 |
|
| 2019 |
Balsa E, Soustek MS, Thomas A, Cogliati S, García-Poyatos C, Martín-García E, Jedrychowski M, Gygi SP, Enriquez JA, Puigserver P. ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis. Molecular Cell. PMID 31023583 DOI: 10.1016/J.Molcel.2019.03.031 |
0.344 |
|
| 2018 |
Soustek MS, Balsa E, Barrow JJ, Jedrychowski M, Vogel R, Jan Smeitink, Gygi SP, Puigserver P. Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells. Cell Death & Disease. 9: 658. PMID 29855477 DOI: 10.1038/S41419-018-0696-5 |
0.308 |
|
| 2018 |
Puigserver P. PGC1a at the Nexus of Cancer Stem Cell Fates Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.391 |
0.384 |
|
| 2017 |
Hatting M, Tavares CDJ, Sharabi K, Rines AK, Puigserver P. Insulin regulation of gluconeogenesis. Annals of the New York Academy of Sciences. PMID 28868790 DOI: 10.1111/Nyas.13435 |
0.418 |
|
| 2017 |
Puigserver P, Luo C, Balsa E, Thomas A, Hatting M, Jedrychowski M, Gygi SP, Widlund HR. ERRα maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-elevated Melanomas. Molecular Cancer Research : McR. PMID 28596418 DOI: 10.1158/1541-7786.Mcr-17-0143 |
0.39 |
|
| 2017 |
Sharabi K, Lin H, Tavares CD, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, ... ... Puigserver P, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 169: 148-160.e15. PMID 28340340 DOI: 10.1016/J.Cell.2017.03.001 |
0.407 |
|
| 2017 |
Pan Y, Tian T, Park CO, Lofftus SY, Mei S, Liu X, Luo C, O'Malley JT, Gehad A, Teague JE, Divito SJ, Fuhlbrigge R, Puigserver P, Krueger JG, Hotamisligil GS, et al. Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism. Nature. PMID 28219080 DOI: 10.1038/Nature21379 |
0.541 |
|
| 2017 |
Hatting M, Rines AK, Luo C, Tabata M, Sharabi K, Hall JA, Verdeguer F, Trautwein C, Puigserver P. Adipose Tissue CLK2 Promotes Energy Expenditure during High-Fat Diet Intermittent Fasting. Cell Metabolism. PMID 28089567 DOI: 10.1016/J.Cmet.2016.12.007 |
0.365 |
|
| 2017 |
Pan Y, Tian T, Park C, Lofftus S, Mei S, Liu X, Luo C, O'Malley J, Gehad A, Teague J, Divito S, Fuhlbrigge R, Puigserver P, Krueger J, Hotamisligil G, et al. 055 Tissue resident memory T cell survival requires exogenous lipid uptake and metabolism Journal of Investigative Dermatology. 137: S10. DOI: 10.1016/J.Jid.2017.02.068 |
0.484 |
|
| 2016 |
Luo C, Widlund HR, Puigserver P. PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors. Trends in Cancer. 2: 619-631. PMID 28607951 DOI: 10.1016/J.Trecan.2016.09.006 |
0.379 |
|
| 2016 |
Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Molecular Cell. PMID 27666594 DOI: 10.1016/J.Molcel.2016.08.023 |
0.343 |
|
| 2016 |
Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P. A PGC1α-mediated transcriptional axis suppresses melanoma metastasis. Nature. PMID 27580028 DOI: 10.1038/Nature19347 |
0.397 |
|
| 2016 |
Rines AK, Sharabi K, Tavares CD, Puigserver P. Targeting hepatic glucose metabolism in the treatment of type 2 diabetes. Nature Reviews. Drug Discovery. PMID 27516169 DOI: 10.1038/Nrd.2016.151 |
0.351 |
|
| 2016 |
Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyl Transferase and the PGC-1α Transcriptional Coactivator. The Journal of Biological Chemistry. PMID 27022023 DOI: 10.1074/Jbc.M115.706200 |
0.458 |
|
| 2016 |
Lee G, Won HS, Lee YM, Choi JW, Oh TI, Jang JH, Choi DK, Lim BO, Kim YJ, Park JW, Puigserver P, Lim JH. Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation. Scientific Reports. 6: 18928. PMID 26740011 DOI: 10.1038/Srep18928 |
0.317 |
|
| 2015 |
Sharabi K, Tavares CD, Rines AK, Puigserver P. Molecular pathophysiology of hepatic glucose production. Molecular Aspects of Medicine. 46: 21-33. PMID 26549348 DOI: 10.1016/J.Mam.2015.09.003 |
0.374 |
|
| 2015 |
Verdeguer F, Soustek MS, Hatting M, Blättler SM, McDonald D, Barrow JJ, Puigserver P. Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity. Molecular and Cellular Biology. PMID 26503783 DOI: 10.1128/Mcb.00722-15 |
0.372 |
|
| 2015 |
Soustek MS, Puigserver P. Interrupting synoviolin play at the ER: a plausible action to elevate mitochondrial energetics and silence obesity. The Embo Journal. 34: 981-3. PMID 25736377 DOI: 10.15252/Embj.201591240 |
0.377 |
|
| 2014 |
Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51. PMID 24870244 DOI: 10.1038/Nature13267 |
0.434 |
|
| 2014 |
Lim JH, Luo C, Vazquez F, Puigserver P. Targeting mitochondrial oxidative metabolism in melanoma causes metabolic compensation through glucose and glutamine utilization. Cancer Research. 74: 3535-45. PMID 24812272 DOI: 10.1158/0008-5472.Can-13-2893-T |
0.396 |
|
| 2014 |
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, ... ... Puigserver P, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 508: 258-62. PMID 24717514 DOI: 10.1038/Nature13198 |
0.751 |
|
| 2014 |
Hall JA, Tabata M, Rodgers JT, Puigserver P. USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Molecular Endocrinology (Baltimore, Md.). 28: 912-24. PMID 24694308 DOI: 10.1210/Me.2013-1420 |
0.773 |
|
| 2014 |
Verdeguer F, Blättler SM, Cunningham JT, Hall JA, Chim H, Puigserver P. Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms. Molecular Endocrinology (Baltimore, Md.). 28: 308-16. PMID 24467246 DOI: 10.1210/Me.2013-1173 |
0.454 |
|
| 2014 |
Tabata M, Rodgers JT, Hall JA, Lee Y, Jedrychowski MP, Gygi SP, Puigserver P. Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex. Diabetes. 63: 1519-32. PMID 24458359 DOI: 10.2337/Db13-1304 |
0.748 |
|
| 2013 |
Dominy J, Puigserver P, Cantó C. In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity. Methods in Molecular Biology (Clifton, N.J.). 1077: 217-37. PMID 24014410 DOI: 10.1007/978-1-62703-637-5_15 |
0.306 |
|
| 2013 |
Dominy JE, Puigserver P. Mitochondrial biogenesis through activation of nuclear signaling proteins. Cold Spring Harbor Perspectives in Biology. 5. PMID 23818499 DOI: 10.1101/Cshperspect.A015008 |
0.359 |
|
| 2013 |
Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell. 23: 287-301. PMID 23416000 DOI: 10.1016/J.Ccr.2012.11.020 |
0.57 |
|
| 2013 |
Lim JH, Gerhart-Hines Z, Dominy JE, Lee Y, Kim S, Tabata M, Xiang YK, Puigserver P. Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex. The Journal of Biological Chemistry. 288: 7117-26. PMID 23329830 DOI: 10.1074/Jbc.M112.415729 |
0.358 |
|
| 2012 |
Dominy JE, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, ... Puigserver P, et al. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular Cell. 48: 900-13. PMID 23142079 DOI: 10.1016/J.Molcel.2012.09.030 |
0.473 |
|
| 2012 |
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, ... Puigserver P, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 151: 96-110. PMID 23021218 DOI: 10.1016/J.Cell.2012.08.034 |
0.799 |
|
| 2012 |
Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, et al. A metabolic prosurvival role for PML in breast cancer. The Journal of Clinical Investigation. 122: 3088-100. PMID 22886304 DOI: 10.1172/Jci62129 |
0.334 |
|
| 2012 |
Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Molecular and Cellular Biology. 32: 3333-46. PMID 22711985 DOI: 10.1128/Mcb.00337-12 |
0.407 |
|
| 2012 |
Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P. Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. Cell Metabolism. 15: 505-17. PMID 22482732 DOI: 10.1016/J.Cmet.2012.03.008 |
0.384 |
|
| 2011 |
Dominy JE, Gerhart-Hines Z, Puigserver P. Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming. Cold Spring Harbor Symposia On Quantitative Biology. 76: 203-9. PMID 22371372 DOI: 10.1101/Sqb.2012.76.010843 |
0.364 |
|
| 2011 |
Gerhart-Hines Z, Dominy JE, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Molecular Cell. 44: 851-63. PMID 22195961 DOI: 10.1016/J.Molcel.2011.12.005 |
0.416 |
|
| 2011 |
Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA. Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 108: 20808-13. PMID 22143799 DOI: 10.1073/Pnas.1111448109 |
0.416 |
|
| 2011 |
Bhalla K, Hwang BJ, Dewi RE, Ou L, Twaddel W, Fang HB, Vafai SB, Vazquez F, Puigserver P, Boros L, Girnun GD. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Research. 71: 6888-98. PMID 21914785 DOI: 10.1158/0008-5472.Can-11-1011 |
0.435 |
|
| 2011 |
Rodgers JT, Vogel RO, Puigserver P. Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. Molecular Cell. 41: 471-9. PMID 21329884 DOI: 10.1016/J.Molcel.2011.02.007 |
0.741 |
|
| 2010 |
Dominy JE, Puigserver P. Nuclear FoxO1 inflames insulin resistance. The Embo Journal. 29: 4068-9. PMID 21157481 DOI: 10.1038/Emboj.2010.305 |
0.369 |
|
| 2010 |
Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, ... ... Puigserver P, et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes & Development. 24: 1403-17. PMID 20595232 DOI: 10.1101/Gad.1901210 |
0.754 |
|
| 2010 |
Rodgers JT, Haas W, Gygi SP, Puigserver P. Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. Cell Metabolism. 11: 23-34. PMID 20074525 DOI: 10.1016/J.Cmet.2009.11.006 |
0.763 |
|
| 2010 |
Dominy JE, Lee Y, Gerhart-Hines Z, Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochimica Et Biophysica Acta. 1804: 1676-83. PMID 20005308 DOI: 10.1016/J.Bbapap.2009.11.023 |
0.523 |
|
| 2009 |
Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF. Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nature Medicine. 15: 1307-11. PMID 19838201 DOI: 10.1038/Nm.2049 |
0.779 |
|
| 2009 |
Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461: 109-13. PMID 19693011 DOI: 10.1038/Nature08268 |
0.36 |
|
| 2009 |
Kelly TJ, Lerin C, Haas W, Gygi SP, Puigserver P. GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. The Journal of Biological Chemistry. 284: 19945-52. PMID 19491097 DOI: 10.1074/Jbc.M109.015164 |
0.473 |
|
| 2009 |
Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature. 458: 1056-60. PMID 19262508 DOI: 10.1038/Nature07813 |
0.489 |
|
| 2009 |
Rodgers JT, Puigserver P. Insulin resistance: beta-arrestin development. Cell Research. 19: 275-6. PMID 19252509 DOI: 10.1038/Cr.2009.22 |
0.697 |
|
| 2009 |
Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW. A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. The Journal of Biological Chemistry. 284: 5148-57. PMID 19103600 DOI: 10.1074/Jbc.M808890200 |
0.771 |
|
| 2009 |
Suchankova G, Nelson LE, Gerhart-Hines Z, Kelly M, Gauthier MS, Saha AK, Ido Y, Puigserver P, Ruderman NB. Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. Biochemical and Biophysical Research Communications. 378: 836-41. PMID 19071085 DOI: 10.1016/J.Bbrc.2008.11.130 |
0.387 |
|
| 2008 |
Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proceedings of the National Academy of Sciences of the United States of America. 105: 17187-92. PMID 18957541 DOI: 10.1073/Pnas.0808207105 |
0.498 |
|
| 2008 |
Housley MP, Rodgers JT, Udeshi ND, Kelly TJ, Shabanowitz J, Hunt DF, Puigserver P, Hart GW. O-GlcNAc regulates FoxO activation in response to glucose. The Journal of Biological Chemistry. 283: 16283-92. PMID 18420577 DOI: 10.1074/Jbc.M802240200 |
0.755 |
|
| 2008 |
Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. Febs Letters. 582: 46-53. PMID 18036349 DOI: 10.1016/J.Febslet.2007.11.034 |
0.782 |
|
| 2007 |
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature. 450: 736-40. PMID 18046414 DOI: 10.1038/Nature06322 |
0.781 |
|
| 2007 |
Rodgers JT, Puigserver P. Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proceedings of the National Academy of Sciences of the United States of America. 104: 12861-6. PMID 17646659 DOI: 10.1073/Pnas.0702509104 |
0.779 |
|
| 2007 |
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. The Embo Journal. 26: 3169-79. PMID 17581637 DOI: 10.1038/Sj.Emboj.7601758 |
0.702 |
|
| 2007 |
Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. The Embo Journal. 26: 1913-23. PMID 17347648 DOI: 10.1038/Sj.Emboj.7601633 |
0.781 |
|
| 2007 |
Rodgers JT, Puigserver P. Receptor feasts on sugar and cholesterol. Nature Medicine. 13: 128-9. PMID 17290267 DOI: 10.1038/Nm0207-128 |
0.724 |
|
| 2006 |
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 127: 1109-22. PMID 17112576 DOI: 10.1016/J.Cell.2006.11.013 |
0.499 |
|
| 2006 |
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, ... ... Puigserver P, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 444: 337-42. PMID 17086191 DOI: 10.1038/Nature05354 |
0.323 |
|
| 2006 |
Cha SH, Rodgers JT, Puigserver P, Chohnan S, Lane MD. Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. Proceedings of the National Academy of Sciences of the United States of America. 103: 15410-5. PMID 17030788 DOI: 10.1073/Pnas.0607334103 |
0.767 |
|
| 2006 |
Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A, Puigserver P. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metabolism. 3: 429-38. PMID 16753578 DOI: 10.1016/J.Cmet.2006.04.013 |
0.784 |
|
| 2006 |
Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, et al. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. The Journal of Biological Chemistry. 281: 21745-54. PMID 16751189 DOI: 10.1074/Jbc.M602909200 |
0.728 |
|
| 2006 |
Rodgers JT, Puigserver P. Certainly can't live without this: SIRT6. Cell Metabolism. 3: 77-8. PMID 16459306 DOI: 10.1016/J.Cmet.2006.01.009 |
0.698 |
|
| 2006 |
Puigserver P, Rodgers JT. Foxa2, a novel transcriptional regulator of insulin sensitivity. Nature Medicine. 12: 38-9. PMID 16397559 DOI: 10.1038/Nm0106-38 |
0.75 |
|
| 2005 |
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 434: 113-8. PMID 15744310 DOI: 10.1038/Nature03354 |
0.809 |
|
| 2005 |
Puigserver P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. International Journal of Obesity (2005). 29: S5-9. PMID 15711583 DOI: 10.1038/Sj.Ijo.0802905 |
0.534 |
|
| 2004 |
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proceedings of the National Academy of Sciences of the United States of America. 101: 6570-5. PMID 15100410 DOI: 10.1073/Pnas.0401401101 |
0.634 |
|
| 2004 |
Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, Bai X, Floering LM, Spiegelman BM, Collins S. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Molecular and Cellular Biology. 24: 3057-67. PMID 15024092 DOI: 10.1128/Mcb.24.7.3057-3067.2004 |
0.61 |
|
| 2004 |
Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jäeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM. Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes & Development. 18: 278-89. PMID 14744933 DOI: 10.1101/Gad.1152204 |
0.736 |
|
| 2003 |
Yoon JC, Xu G, Deeney JT, Yang SN, Rhee J, Puigserver P, Levens AR, Yang R, Zhang CY, Lowell BB, Berggren PO, Newgard CB, Bonner-Weir S, Weir G, Spiegelman BM. Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Developmental Cell. 5: 73-83. PMID 12852853 DOI: 10.1016/S1534-5807(03)00170-9 |
0.628 |
|
| 2003 |
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics. 34: 267-73. PMID 12808457 DOI: 10.1038/Ng1180 |
0.587 |
|
| 2003 |
Lin J, Tarr PT, Yang R, Rhee J, Puigserver P, Newgard CB, Spiegelman BM. PGC-1beta in the regulation of hepatic glucose and energy metabolism. The Journal of Biological Chemistry. 278: 30843-8. PMID 12807885 DOI: 10.1074/Jbc.M303643200 |
0.759 |
|
| 2003 |
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423: 550-5. PMID 12754525 DOI: 10.1038/Nature01667 |
0.648 |
|
| 2003 |
Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ, Spiegelman BM. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 4012-7. PMID 12651943 DOI: 10.1073/Pnas.0730870100 |
0.634 |
|
| 2003 |
Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocrine Reviews. 24: 78-90. PMID 12588810 DOI: 10.1210/Er.2002-0012 |
0.657 |
|
| 2003 |
Tritos NA, Mastaitis JW, Kokkotou EG, Puigserver P, Spiegelman BM, Maratos-Flier E. Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain. Brain Research. 961: 255-60. PMID 12531492 DOI: 10.1016/S0006-8993(02)03961-6 |
0.583 |
|
| 2002 |
Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 418: 797-801. PMID 12181572 DOI: 10.1038/Nature00904 |
0.726 |
|
| 2002 |
Lin J, Puigserver P, Donovan J, Tarr P, Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. The Journal of Biological Chemistry. 277: 1645-8. PMID 11733490 DOI: 10.1074/Jbc.C100631200 |
0.74 |
|
| 2001 |
Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang CY, Krauss S, Mootha VK, Lowell BB, Spiegelman BM. Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Molecular Cell. 8: 971-82. PMID 11741533 DOI: 10.1016/S1097-2765(01)00390-2 |
0.694 |
|
| 2001 |
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131 |
0.639 |
|
| 2001 |
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 413: 131-8. PMID 11557972 DOI: 10.1038/35093050 |
0.63 |
|
| 2001 |
Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, Lehman JJ, Kelly DP, Spiegelman BM. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proceedings of the National Academy of Sciences of the United States of America. 98: 3820-5. PMID 11274399 DOI: 10.1073/Pnas.061035098 |
0.571 |
|
| 2001 |
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Erratum: correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature. 413: 652-652. DOI: 10.1038/35098123 |
0.556 |
|
| 2000 |
Spiegelman BM, Puigserver P, Wu Z. Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 24: S8-10. PMID 11126248 DOI: 10.1038/Sj.Ijo.0801492 |
0.605 |
|
| 2000 |
Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Molecular Cell. 6: 307-16. PMID 10983978 DOI: 10.1016/S1097-2765(00)00031-9 |
0.34 |
|
| 2000 |
Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM. Transcriptional regulation of adipogenesis. Genes & Development. 14: 1293-307. PMID 10837022 DOI: 10.1101/Gad.14.11.1293 |
0.636 |
|
| 2000 |
Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP. Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. The Journal of Biological Chemistry. 275: 16302-8. PMID 10748020 DOI: 10.1074/Jbc.M001364200 |
0.53 |
|
| 1999 |
Wu Z, Puigserver P, Spiegelman BM. Transcriptional activation of adipogenesis. Current Opinion in Cell Biology. 11: 689-94. PMID 10600710 DOI: 10.1016/S0955-0674(99)00037-X |
0.38 |
|
| 1999 |
Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM. Activation of PPARgamma coactivator-1 through transcription factor docking. Science (New York, N.Y.). 286: 1368-71. PMID 10558993 DOI: 10.1126/Science.286.5443.1368 |
0.562 |
|
| 1999 |
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 98: 115-24. PMID 10412986 DOI: 10.1016/S0092-8674(00)80611-X |
0.585 |
|
| 1999 |
Serra F, Bonet ML, Puigserver P, Oliver J, Palou A. Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoids. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 23: 650-5. PMID 10411240 DOI: 10.1038/Sj.Ijo.0800897 |
0.369 |
|
| 1998 |
Picó C, Puigserver P, Oliver P, Palou A. 2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation. Molecular and Cellular Biochemistry. 189: 1-7. PMID 9879647 DOI: 10.1023/A:1006835124149 |
0.308 |
|
| 1998 |
Puigserver P, Ribot J, Serra F, Gianotti M, Bonet ML, Nadal-Ginard B, Palou A. Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha. European Journal of Cell Biology. 77: 117-23. PMID 9840461 DOI: 10.1016/S0171-9335(98)80079-4 |
0.367 |
|
| 1998 |
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92: 829-39. PMID 9529258 DOI: 10.1016/S0092-8674(00)81410-5 |
0.613 |
|
| 1997 |
Garcia-Palmer FJ, Pericas J, Matamala JC, Puigserver P, Bonet ML, Palou A, Gianotti M. Diminished response to food deprivation of the rat brown adipose tissue mitochondrial uncoupling system with age. Biochemistry and Molecular Biology International. 42: 1151-61. PMID 9305533 DOI: 10.1080/15216549700203621 |
0.317 |
|
| 1997 |
Bonet ML, Puigserver P, Serra F, Ribot J, Vázquez F, Pico C, Palou A. Retinoic acid modulates retinoid X receptor alpha and retinoic acid receptor alpha levels of cultured brown adipocytes. Febs Letters. 406: 196-200. PMID 9109417 DOI: 10.1016/S0014-5793(97)00274-3 |
0.395 |
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