| Year |
Citation |
Score |
| 2020 |
Washko GR, Nardelli P, Ash SY, Rahaghi FN, Vegas Sanchez-Ferrero G, Come CE, Dransfield MT, Kalhan R, Han MK, Bhatt SP, Wells JM, Pistenmaa CL, Diaz AA, Ross JC, Rennard S, et al. Smaller Left Ventricle Size at Noncontrast CT Is Associated with Lower Mortality in COPDGene Participants. Radiology. 191793. PMID 32368963 DOI: 10.1148/Radiol.2020191793 |
0.335 |
|
| 2020 |
Wilson AC, Kumar PL, Lee S, Parker MM, Arora I, Morrow JD, Wouters EFM, Casaburi R, Rennard SI, Lomas DA, Agusti A, Tal-Singer R, Dransfield MT, Wells JM, Bhatt SP, et al. Heme metabolism genes Downregulated in COPD Cachexia. Respiratory Research. 21: 100. PMID 32354332 DOI: 10.1186/S12931-020-01336-W |
0.354 |
|
| 2020 |
Singh D, Bafadhel M, Brightling CE, Sciurba FC, Curtis JL, Martinez FJ, Pasquale CB, Merrill DD, Metzdorf N, Petruzzelli S, Tal-Singer R, Compton C, Rennard S, Martin UJ. Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 32186896 DOI: 10.1164/Rccm.201912-2384Pp |
0.322 |
|
| 2019 |
Castaldi PJ, Boueiz A, Yun J, San Jose Estepar R, Ross JC, Washko G, Cho MH, Hersh CP, Kinney GL, Young KA, Regan EA, Lynch DA, Criner GJ, Dy JG, Rennard SI, et al. Machine Learning Characterization of COPD Subtypes: Insights from the COPDGene Study. Chest. PMID 31887283 DOI: 10.1016/J.Chest.2019.11.039 |
0.377 |
|
| 2019 |
Nunez FJ, Schulte NA, Fogel DM, Michalski J, Rennard SI, Penn RB, Toews ML, Ostrom RS. Agonist-specific desensitization of PGE-stimulated cAMP signaling due to upregulated phosphodiesterase expression in human lung fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 31884570 DOI: 10.1007/S00210-019-01800-5 |
0.319 |
|
| 2019 |
Müllerová H, Dransfield MT, Thomashow B, Jones PW, Rennard S, Karlsson N, Fageras M, Metzdorf N, Petruzzelli S, Rommes J, Sciurba FC, Tabberer M, Merrill D, Tal-Singer R. Clinical Development and Research Applications of the COPD Assessment Test (CAT). American Journal of Respiratory and Critical Care Medicine. PMID 31815521 DOI: 10.1164/Rccm.201907-1369Pp |
0.366 |
|
| 2019 |
Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, ... ... Rennard SI, et al. COPDGene 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 6: 384-399. PMID 31710793 DOI: 10.15326/Jcopdf.6.5.2019.0149 |
0.372 |
|
| 2019 |
Ortega VE, Li X, O'Neal WK, Lackey L, Ampleford E, Hawkins GA, Grayeski PJ, Laederach A, Barjaktarevic I, Barr RG, Cooper C, Couper D, Han MK, Kanner RE, Kleerup EC, ... ... Rennard SI, et al. The Effects of Rare Variants on Lung Function and Emphysema in SPIROMICS. American Journal of Respiratory and Critical Care Medicine. PMID 31661293 DOI: 10.1164/Rccm.201904-0769Oc |
0.324 |
|
| 2019 |
Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, ... ... Rennard SI, et al. Radiographic Lung Volumes Predict Progression to COPD in Smokers with Preserved Spirometry in SPIROMICS. The European Respiratory Journal. PMID 31439683 DOI: 10.1183/13993003.02214-2018 |
0.376 |
|
| 2019 |
Halper-Stromberg E, Gillenwater L, Cruickshank-Quinn C, O'Neal WK, Reisdorph N, Petrache I, Zhuang Y, Labaki WW, Curtis JL, Wells J, Rennard S, Pratte KA, Woodruff P, Stringer KA, Kechris K, et al. Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma. Metabolites. 9. PMID 31349744 DOI: 10.3390/Metabo9080157 |
0.364 |
|
| 2019 |
Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, ... ... Rennard SI, et al. Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS). Respiratory Research. 20: 153. PMID 31307479 DOI: 10.1186/S12931-019-1121-Z |
0.301 |
|
| 2019 |
Chen J, Cho M, Silverman EK, Hokanson JE, Kinney GL, Crapo JD, Rennard S, Dy J, Castaldi P. Turning subtypes into disease axes to improve prediction of COPD progression. Thorax. PMID 31189730 DOI: 10.1136/Thoraxjnl-2018-213005 |
0.358 |
|
| 2019 |
McDonald MN, Wouters EFM, Rutten E, Casaburi R, Rennard SI, Lomas DA, Bamman M, Celli B, Agusti A, Tal-Singer R, Hersh CP, Dransfield M, Silverman EK. It's more than low BMI: prevalence of cachexia and associated mortality in COPD. Respiratory Research. 20: 100. PMID 31118043 DOI: 10.1186/S12931-019-1073-3 |
0.339 |
|
| 2019 |
Thomashow B, Crapo JD, Drummond MB, Han MK, Kalhan R, Malanga E, Malanga V, Mannino DM, Rennard S, Sciurba FC, Willard KS, Wise R, Yawn B. Introducing the New COPD Pocket Consultant Guide App: Can A Digital Approach Improve Care? A Statement of the COPD Foundation. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 6. PMID 31075813 DOI: 10.15326/Jcopdf.6.3.2018.0167 |
0.357 |
|
| 2019 |
Jenkins C, FitzGerald JM, Martinez FJ, Postma DS, Rennard S, van der Molen T, Gardev A, Genofre E, Calverley P. Diagnosis and management of asthma, COPD and asthma-COPD overlap among primary care physicians and respiratory/allergy specialists: a global survey. The Clinical Respiratory Journal. PMID 30825365 DOI: 10.1111/Crj.13016 |
0.345 |
|
| 2019 |
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, ... ... Rennard SI, et al. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nature Genetics. PMID 30804561 DOI: 10.1038/S41588-018-0342-2 |
0.405 |
|
| 2019 |
Reddel HK, Gerhardsson de Verdier M, Agustí A, Anderson G, Beasley R, Bel EH, Janson C, Make B, Martin RJ, Pavord I, Price D, Keen C, Gardev A, Rennard S, Sveréus A, et al. Prospective observational study in patients with obstructive lung disease: NOVELTY design. Erj Open Research. 5. PMID 30723727 DOI: 10.1183/23120541.00036-2018 |
0.389 |
|
| 2019 |
Wells JM, Arenberg DA, Barjaktarevic I, Bhatt SP, Bowler RP, Christenson SA, Couper DJ, Dransfield MT, Han MK, Hoffman EA, Kaner RJ, Kim V, Kleerup E, Martinez FJ, Moore WC, ... ... Rennard SI, et al. Safety and Tolerability of Comprehensive Research Bronchoscopy in COPD: Results from the SPIROMICS Bronchoscopy Sub-Study. Annals of the American Thoracic Society. PMID 30653926 DOI: 10.1513/Annalsats.201807-441Oc |
0.392 |
|
| 2019 |
Rennard SI. Advancing Chronic Obstructive Pulmonary Disease Therapy: Opportunities, Challenges, and Excitement. American Journal of Respiratory Cell and Molecular Biology. 60: 1-2. PMID 30562048 DOI: 10.1165/Rcmb.2018-0288Ed |
0.36 |
|
| 2019 |
Vestbo J, Reddel HK, Agustí A, Bel EH, Janson C, Make B, Price D, Hughes R, Rapsomaniki E, Karlsson N, Nuevo J, Rennard SI, Giorgio-Miller AD, Alacqua M, Verdier MGD. Characteristics by physician-assigned severity of asthma, asthma+COPD and COPD patients in the NOVELTY study European Respiratory Journal. 54. DOI: 10.1183/13993003.Congress-2019.Pa5029 |
0.35 |
|
| 2018 |
Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Graham Barr R, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, ... ... Rennard SI, et al. Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Respiratory Research. 19: 178. PMID 30227877 DOI: 10.1186/S12931-018-0888-7 |
0.312 |
|
| 2018 |
Qiao D, Ameli A, Prokopenko D, Chen H, Kho AT, Parker MM, Morrow J, Hobbs BD, Liu Y, Beaty TH, Crapo JD, Barnes KC, Nickerson DA, Bamshad M, Hersh CP, ... ... Rennard SI, et al. Whole exome sequencing analysis in severe chronic obstructive pulmonary disease. Human Molecular Genetics. PMID 30060175 DOI: 10.1093/Hmg/Ddy269 |
0.35 |
|
| 2018 |
Leidy NK, Martinez FJ, Malley KG, Mannino DM, Han MK, Bacci ED, Brown RW, Houfek JF, Labaki WW, Make BJ, Meldrum CA, Quezada W, Rennard S, Thomashow B, Yawn BP. Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment? International Journal of Chronic Obstructive Pulmonary Disease. 13: 1901-1912. PMID 29942123 DOI: 10.2147/Copd.S152226 |
0.337 |
|
| 2018 |
Martinez FJ, Rabe KF, Calverley PMA, Fabbri LM, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VKT, Siddiqui S, Reisner C, Zetterstrand S, Román J, Purkayastha D, Bagul N, ... Rennard SI, et al. Determinants of Response to Roflumilast in Severe COPD: Pooled Analysis of Two Randomized Trials. American Journal of Respiratory and Critical Care Medicine. PMID 29763572 DOI: 10.1164/Rccm.201712-2493Oc |
0.401 |
|
| 2018 |
Patel NR, Cunoosamy DM, Fagerås M, Taib Z, Asimus S, Hegelund-Myrbäck T, Lundin S, Pardali K, Kurian N, Ersdal E, Kristensson C, Korsback K, Palmér R, Brown MN, Greenaway S, ... ... Rennard SI, et al. The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial. International Journal of Chronic Obstructive Pulmonary Disease. 13: 1009-1019. PMID 29628759 DOI: 10.2147/Copd.S150576 |
0.369 |
|
| 2018 |
Watz H, Bagul N, Rabe KF, Rennard S, Alagappan VK, Román J, Facius A, Calverley PM. Use of a 4-week up-titration regimen of roflumilast in patients with severe COPD. International Journal of Chronic Obstructive Pulmonary Disease. 13: 813-822. PMID 29563781 DOI: 10.2147/Copd.S154012 |
0.309 |
|
| 2018 |
Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley P, Celli BR, Christenson SA, Crystal RG, Fagerås M, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, ... ... Rennard SI, et al. At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 29406779 DOI: 10.1164/Rccm.201710-2028Pp |
0.341 |
|
| 2018 |
Smith BM, Traboulsi H, Austin JHM, Manichaikul A, Hoffman EA, Bleecker ER, Cardoso WV, Cooper C, Couper DJ, Dashnaw SM, Guo J, Han MK, Hansel NN, Hughes EW, Jacobs DR, ... ... Rennard S, et al. Human airway branch variation and chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339516 DOI: 10.1073/Pnas.1715564115 |
0.42 |
|
| 2018 |
Bafadhel M, Peterson S, De Blas MA, Calverley PM, Rennard SI, Richter K, Fagerås M. Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials. The Lancet. Respiratory Medicine. PMID 29331313 DOI: 10.1016/S2213-2600(18)30006-7 |
0.384 |
|
| 2018 |
Bhatt SP, Kim YI, Harrington KF, Hokanson JE, Lutz SM, Cho MH, DeMeo DL, Wells JM, Make BJ, Rennard SI, Washko GR, Foreman MG, Tashkin DP, Wise RA, Dransfield MT, et al. Smoking duration alone provides stronger risk estimates of chronic obstructive pulmonary disease than pack-years. Thorax. PMID 29326298 DOI: 10.1136/Thoraxjnl-2017-210722 |
0.369 |
|
| 2017 |
Abdulai RM, Jellesmark Jensen T, Patel NR, Polkey MI, Jansson P, Celli BR, Rennard SI. Deterioration of Limb Muscle Function During Acute Exacerbation of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 29064260 DOI: 10.1164/Rccm.201703-0615Ci |
0.325 |
|
| 2017 |
Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, ... ... Rennard SI, et al. Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. The Journal of Allergy and Clinical Immunology. PMID 28916185 DOI: 10.1016/J.Jaci.2017.07.039 |
0.428 |
|
| 2017 |
Ikari J, Nelson AJ, Obaid J, Giron-Martinez A, Ikari K, Makino F, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Demeo D, Feghali-Bostwick C, Holz O, Rabe K, ... ... Rennard SI, et al. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. Plos One. 12: e0184039. PMID 28880936 DOI: 10.1371/Journal.Pone.0184039 |
0.605 |
|
| 2017 |
Yawn BB, Thomashaw B, Mannino DM, Han MK, Kalhan R, Rennard S, Cerrata S, Crapo JD, Wise R. The 2017 Update to the COPD Foundation COPD Pocket Consultant Guide. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 4: 177-185. PMID 28848929 DOI: 10.15326/Jcopdf.4.3.2017.0136 |
0.355 |
|
| 2017 |
Jones PW, Gelhorn H, Karlsson N, Menjoge S, Müllerova H, Rennard SI, Tal-Singer R, Wilson H, Merrill D, Tabberer M. Baseline Severity as Predictor of Change in St George's Respiratory Questionnaire Scores in Trials of Long-acting Bronchodilators with COPD Patients. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 4: 132-140. PMID 28848922 DOI: 10.15326/Jcopdf.4.2.2017.0129 |
0.369 |
|
| 2017 |
Jones PW, Gelhorn H, Wilson H, Karlsson N, Menjoge S, Müllerova H, Rennard SI, Tal-Singer R, Merrill D, Tabberer M. Responder Analyses for Treatment Effects in COPD Using the St George's Respiratory Questionnaire. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 4: 124-131. PMID 28848921 DOI: 10.15326/Jcopdf.4.2.2017.0130 |
0.323 |
|
| 2017 |
Martinez FJ, Han M, Leidy N, Make B, Mannino DM, Rennard SI, Thomashow BM, Yawn BP. Reply to CAPTURETM© a Screening Tool for COPD or Obstructive Airways Disease? American Journal of Respiratory and Critical Care Medicine. PMID 28723257 DOI: 10.1164/Rccm.201707-1393Le |
0.343 |
|
| 2017 |
McCamley JD, Pisciotta EJ, Yentes JM, Wurdeman SR, Rennard SI, Pipinos II, Johanning JM, Myers SA. Gait deficiencies associated with peripheral artery disease are different than chronic obstructive pulmonary disease. Gait & Posture. 57: 258-264. PMID 28683417 DOI: 10.1016/J.Gaitpost.2017.06.018 |
0.371 |
|
| 2017 |
Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, ... ... Rennard S, et al. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. The Lancet. Respiratory Medicine. PMID 28668356 DOI: 10.1016/S2213-2600(17)30207-2 |
0.392 |
|
| 2017 |
Castaldi PJ, Benet M, Petersen H, Rafaels N, Finigan J, Paoletti M, Marike Boezen H, Vonk JM, Bowler R, Pistolesi M, Puhan MA, Anto J, Wauters E, Lambrechts D, Janssens W, ... ... Rennard S, et al. Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts. Thorax. PMID 28637835 DOI: 10.1136/Thoraxjnl-2016-209846 |
0.322 |
|
| 2017 |
Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, ... ... Rennard SI, et al. Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Annals of the American Thoracic Society. 14: 636-642. PMID 28459622 DOI: 10.1513/Annalsats.201610-815Oc |
0.371 |
|
| 2017 |
Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, ... ... Rennard S, et al. Integrative Genomics of Emphysema Associated Genes Reveals Potential Disease Biomarkers. American Journal of Respiratory Cell and Molecular Biology. PMID 28459279 DOI: 10.1165/Rcmb.2016-0284Oc |
0.364 |
|
| 2017 |
Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng RT, McManus B, Miller BE, Rennard S, Paré PD, et al. Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease. Respiratory Research. 18: 72. PMID 28438154 DOI: 10.1186/S12931-017-0558-1 |
0.342 |
|
| 2017 |
Quezada WA, Whippo BA, Jellen PA, Leidy NK, Mannino D, Kim KJ, Han MK, Houfek JF, Make B, Malley KG, Meldrum CA, Rennard S, Yawn BP, Martinez F, Thomashow BM, et al. How well does CAPTURE™ Translate? An Exploratory Analysis of a COPD Case-Finding Method for Spanish-Speaking Patients. Chest. PMID 28414029 DOI: 10.1016/J.Chest.2017.03.047 |
0.328 |
|
| 2017 |
D'Urzo A, Rennard S, Kerwin E, Donohue JF, Lei A, Molins E, Leselbaum A. A randomised double-blind, placebo-controlled, long-term extension study of the efficacy, safety and tolerability of fixed-dose combinations of aclidinium/formoterol or monotherapy in the treatment of chronic obstructive pulmonary disease. Respiratory Medicine. 125: 39-48. PMID 28340861 DOI: 10.1016/J.Rmed.2017.02.008 |
0.342 |
|
| 2017 |
Yentes JM, Rennard SI, Schmid KK, Blanke D, Stergiou N. Patients with COPD Walk with Altered Step Time and Step Width Variability as Compared to Healthy Controls. Annals of the American Thoracic Society. PMID 28267374 DOI: 10.1513/Annalsats.201607-547Oc |
0.358 |
|
| 2017 |
Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, ... ... Rennard SI, et al. Genetic Association and Risk Scores in a COPD Meta-Analysis of 16,707 Subjects. American Journal of Respiratory Cell and Molecular Biology. PMID 28170284 DOI: 10.1165/Rcmb.2016-0331Oc |
0.355 |
|
| 2017 |
Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, ... ... Rennard SI, et al. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics. PMID 28166215 DOI: 10.1038/Ng.3752 |
0.395 |
|
| 2017 |
Han M, Tayob N, Kim V, Murray S, Barr RG, Rennard S, Woodruff P, Cooper C, Kanner R, Bleecker E, Couper D, Hersh C, Wendt C, Dransfield M, Curtis J, et al. Association between emphysema, exacerbations and mortality in the COPDGene and SPIROMICS cohorts European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Oa1496 |
0.356 |
|
| 2016 |
Sethi S, Fogarty C, Hanania NA, Martinez FJ, Rennard S, Fries M, Orevillo C, Darken P, St Rose E, Strom S, Fischer T, Golden M, Dwivedi S, Reisner C. Efficacy of Formoterol Fumarate Delivered by Metered Dose Inhaler Using Co-Suspension™ Delivery Technology Versus Foradil® Aerolizer® in Moderate-To-Severe COPD: A Randomized, Dose-Ranging Study. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 4: 21-33. PMID 28848908 DOI: 10.15326/Jcopdf.4.1.2016.0158 |
0.329 |
|
| 2016 |
Martinez FJ, Rabe KF, Ferguson GT, Fabbri LM, Rennard S, Feldman GJ, Sethi S, Spangenthal S, Gottschlich GM, Rodriguez-Roisin R, Arora S, Siler TM, Siddiqui S, Darken P, Fischer T, et al. Efficacy and Safety of Glycopyrrolate/Formoterol MDI Formulated using Co-Suspension™ Delivery Technology in Patients with COPD. Chest. PMID 27916620 DOI: 10.1016/J.Chest.2016.11.028 |
0.367 |
|
| 2016 |
Martinez FJ, Mannino D, Leidy NK, Malley KG, Bacci ED, Barr RG, Bowler RP, Han MK, Houfek JF, Make B, Meldrum CA, Rennard S, Thomashow B, Walsh J, Yawn BP, et al. A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 27783539 DOI: 10.1164/Rccm.201603-0622Oc |
0.371 |
|
| 2016 |
Andrianopoulos V, Celli BR, Franssen FM, Pinto-Plata VM, Calverley PM, Vanfleteren LE, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EF, et al. Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study. Respiratory Medicine. 119: 87-95. PMID 27692154 DOI: 10.1016/J.Rmed.2016.08.023 |
0.356 |
|
| 2016 |
Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VK, Siddiqui S, Rekeda L, Miller CJ, Zetterstrand S, Reisner C, Rennard SI. Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial. American Journal of Respiratory and Critical Care Medicine. 194: 559-67. PMID 27585384 DOI: 10.1164/Rccm.201607-1349Oc |
0.412 |
|
| 2016 |
Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, et al. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. American Journal of Respiratory and Critical Care Medicine. PMID 27579823 DOI: 10.1164/Rccm.201607-1330Oc |
0.303 |
|
| 2016 |
Rennard SI, Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Siddiqui S, Anzueto A, Zhu H. Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE(2)SPOND rationale and study design. International Journal of Chronic Obstructive Pulmonary Disease. 11: 1921-8. PMID 27574416 DOI: 10.2147/Copd.S109661 |
0.351 |
|
| 2016 |
Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel PW, Toews ML, Wolff DW, Rennard S, Panettieri RA, Casale TB, Tu Y. Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis. Respiratory Research. 17: 103. PMID 27549302 DOI: 10.1186/S12931-016-0418-4 |
0.367 |
|
| 2016 |
Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, ... ... Rennard SI, et al. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Plos Genetics. 12: e1006011. PMID 27532455 DOI: 10.1371/Journal.Pgen.1006011 |
0.322 |
|
| 2016 |
Leung JM, Chen V, Hollander Z, Dai D, Tebbutt SJ, Aaron SD, Vandemheen KL, Rennard SI, FitzGerald JM, Woodruff PG, Lazarus SC, Connett JE, Coxson HO, Miller B, Borchers C, et al. COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry. Plos One. 11: e0161129. PMID 27525416 DOI: 10.1371/Journal.Pone.0161129 |
0.357 |
|
| 2016 |
Sieren JP, Newell JD, Barr RG, Bleecker ER, Burnette N, Carretta EE, Couper D, Goldin J, Guo J, Han MK, Hansel NN, Kanner RE, Kazerooni EA, Martinez FJ, Rennard S, et al. SPIROMICS Protocol for Multicenter Quantitative CT to Phenotype the Lungs. American Journal of Respiratory and Critical Care Medicine. PMID 27482984 DOI: 10.1164/Rccm.201506-1208Pp |
0.358 |
|
| 2016 |
Woodruff PG, Barr RG, Bleecker E, Christenson SA, Couper D, Curtis JL, Gouskova NA, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Lazarus SC, Martinez FJ, Paine R, Rennard S, et al. Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function. The New England Journal of Medicine. 374: 1811-21. PMID 27168432 DOI: 10.1056/Nejmoa1505971 |
0.382 |
|
| 2016 |
Joppa P, Tkacova R, Franssen FM, Hanson C, Rennard SI, Silverman EK, McDonald MN, Calverley PM, Tal-Singer R, Spruit MA, Kenn K, Wouters EF, Rutten EP. Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease. Journal of the American Medical Directors Association. PMID 27161848 DOI: 10.1016/J.Jamda.2016.03.020 |
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| 2016 |
Kim V, Zhao H, Boriek AM, Anzueto A, Soler X, Bhatt SP, Rennard SI, Wise R, Comellas A, Ramsdell JW, Kinney GL, Han MK, Martinez CH, Yen A, Black-Shinn J, et al. Persistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. PMID 27158740 DOI: 10.1513/Annalsats.201512-800Oc |
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| 2016 |
Obeidat M, Ding X, Fishbane N, Hollander Z, Ng RT, McManus B, Tebbutt SJ, Miller BE, Rennard S, Paré PD, Sin DD. The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 27154971 DOI: 10.1093/Ntr/Ntw129 |
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| 2016 |
Rabinovich RA, Miller BE, Wrobel K, Ranjit K, Williams MC, Drost E, Edwards LD, Lomas DA, Rennard SI, Agustí A, Tal-Singer R, Vestbo J, Wouters EF, John M, van Beek EJ, et al. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. The European Respiratory Journal. PMID 27009168 DOI: 10.1183/13993003.01824-2015 |
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| 2016 |
Calverley PM, Rennard SI, Clerisme-Beaty E, Metzdorf N, Zubek VB, ZuWallack R. Effect of tiotropium on night-time awakening and daily rescue medication use in patients with COPD. Respiratory Research. 17: 27. PMID 26971242 DOI: 10.1186/S12931-016-0340-9 |
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| 2016 |
Putcha N, Barr RG, Han MK, Woodruff PG, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP, Eisner MD, Rennard SI, Wise RA, Hansel NN. Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Thorax. PMID 26962015 DOI: 10.1136/Thoraxjnl-2015-207487 |
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| 2016 |
Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, ... ... Rennard SI, et al. Exome Array Analysis Identifies A Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 26771213 DOI: 10.1164/Rccm.201510-2053Oc |
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| 2016 |
Miller BE, Tal-Singer R, Rennard SI, Furtwaengler A, Leidy N, Lowings M, Martin UJ, Martin TR, Merrill DD, Snyder J, Walsh J, Mannino DM. Plasma Fibrinogen Qualification as a Drug Development Tool in COPD: Perspective of the COPD Biomarker Qualification Consortium. American Journal of Respiratory and Critical Care Medicine. PMID 26745765 DOI: 10.1164/Rccm.201509-1722Pp |
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| 2016 |
Smith B, Hoffman E, Bleecker E, Bowler R, Cooper C, Couper D, Comellas A, Dransfield M, MeiLan H, Hansel N, Krishnan J, Martinez F, Paine R, Rennard S, Woodruff P, et al. LATE-BREAKING ABSTRACT: A large airway phenotype among symptomatic smokers with preserved pulmonary function: The subpopulations and intermediate outcome measures in COPD study (SPIROMICS) European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa3829 |
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| 2016 |
Andrianopoulos V, Celli BR, Franssen FME, Pinto-Plata VM, Calverley PMA, Vanfleteren LEGW, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EFM, et al. Exercise-induced oxygen desaturation determinants including pulmonary emphysema in COPD: ECLIPSE data European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1564 |
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| 2016 |
Cascio CL, Bleecker E, Christenson S, Couper D, Curtis J, Hansel N, Hoffman E, Kaner R, Kleerup E, Lazarus S, Martinez F, Paine R, Rennard S, Bowler R, Krishnan J, et al. LATE-BREAKING ABSTRACT: Activity limitation and exacerbations in smokers with emphysema on CT but preserved pulmonary function. SPIROMICS European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa1479 |
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| 2016 |
Toews ML, Schulte NA, Ostrom RS, Rennard SI. Specificity and Mechanisms for Induction of PDE4 Up‐Regulation by PGE2 and Related Agents in Lung Fibroblasts The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.710.9 |
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| 2015 |
Hardin M, Cho MH, McDonald ML, Wan E, Lomas DA, Coxson HO, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, et al. A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease. The Pharmacogenomics Journal. PMID 26503814 DOI: 10.1038/Tpj.2015.65 |
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| 2015 |
Obeidat M, Fishbane N, Nie Y, Chen V, Hollander Z, Tebbutt SJ, Bossé Y, Ng RT, Miller BE, McManus B, Rennard S, Paré PD, Sin DD. The Effect of Statins on Blood Gene Expression in COPD. Plos One. 10: e0140022. PMID 26462087 DOI: 10.1371/Journal.Pone.0140022 |
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| 2015 |
Rennard SI, Sin DD, Tashkin DP, Calverley PM, Radner F. The Relationship among COPD Severity, Inhaled Corticosteroid Use, and the Risk of Pneumonia. Annals of the American Thoracic Society. 12: 1587-9. PMID 26448356 DOI: 10.1513/Annalsats.201506-391Le |
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| 2015 |
Rennard SI. The Promise of Observational Studies (ECLIPSE, SPIROMICS, and COPDGene) in Achieving the Goal of Personalized Treatment of Chronic Obstructive Pulmonary Disease. Seminars in Respiratory and Critical Care Medicine. 36: 478-90. PMID 26238636 DOI: 10.1055/S-0035-1555609 |
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| 2015 |
Han MK, Steenrod AW, Bacci ED, Leidy NK, Mannino DM, Thomashow BM, Barr RG, Make BJ, Bowler RP, Rennard SI, Houfek JF, Yawn BP, Meldrum CA, Walsh JW, Martinez FJ. Identifying Patients with Undiagnosed COPD in Primary Care Settings: Insight from Screening Tools and Epidemiologic Studies. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 2: 103-121. PMID 26236776 DOI: 10.15326/Jcopdf.2.2.2014.0152 |
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| 2015 |
Agustí A, Rennard S, Edwards LD, MacNee W, Wouters E, Miller B, Tal-Singer R, Mullerova H, Celli B. Clinical and prognostic heterogeneity of C and D GOLD groups. The European Respiratory Journal. 46: 250-4. PMID 26130780 DOI: 10.1183/09031936.00012215 |
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| 2015 |
Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 159-72. PMID 26028628 DOI: 10.1183/16000617.00000315 |
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| 2015 |
Leidy NK, Kim K, Bacci ED, Yawn BP, Mannino DM, Thomashow BM, Barr RG, Rennard SI, Houfek JF, Han MK, Meldrum CA, Make BJ, Bowler RP, Steenrod AW, Murray LT, et al. Identifying cases of undiagnosed, clinically significant COPD in primary care: qualitative insight from patients in the target population. Npj Primary Care Respiratory Medicine. 25: 15024. PMID 26028486 DOI: 10.1038/Npjpcrm.2015.24 |
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| 2015 |
Anzueto A, Jenkins CR, Make BJ, Lindberg M, Calverley PM, Fagerås M, Postma DS, Rennard SI, Tashkin DP. Efficacy of an inhaled corticosteroid/long-acting β2-agonist combination in symptomatic COPD patients in GOLD groups B and D. The European Respiratory Journal. 46: 255-8. PMID 26022947 DOI: 10.1183/09031936.00047115 |
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Rennard SI, Drummond MB. Early chronic obstructive pulmonary disease: definition, assessment, and prevention. Lancet (London, England). 385: 1778-88. PMID 25943942 DOI: 10.1016/S0140-6736(15)60647-X |
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Casaburi R, Rennard SI. Exercise limitation in chronic obstructive pulmonary disease. The O'Donnell threshold. American Journal of Respiratory and Critical Care Medicine. 191: 873-5. PMID 25876202 DOI: 10.1164/Rccm.201501-0084Ed |
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Yentes JM, Schmid KK, Blanke D, Romberger DJ, Rennard SI, Stergiou N. Gait mechanics in patients with chronic obstructive pulmonary disease. Respiratory Research. 16: 31. PMID 25849481 DOI: 10.1186/S12931-015-0187-5 |
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| 2015 |
Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. The European Respiratory Journal. 45: 879-905. PMID 25829431 DOI: 10.1183/09031936.00009015 |
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Rennard SI, Dale DC, Donohue JF, Kanniess F, Magnussen H, Sutherland ER, Watz H, Lu S, Stryszak P, Rosenberg E, Staudinger H. CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 191: 1001-11. PMID 25695403 DOI: 10.1164/Rccm.201405-0992Oc |
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| 2015 |
Mannino DM, Tal-Singer R, Lomas DA, Vestbo J, Graham Barr R, Tetzlaff K, Lowings M, Rennard SI, Snyder J, Goldman M, Martin UJ, Merrill D, Martin AL, Simeone JC, Fahrbach K, et al. Plasma Fibrinogen as a Biomarker for Mortality and Hospitalized Exacerbations in People with COPD. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 2: 23-34. PMID 25685850 DOI: 10.15326/Jcopdf.2.1.2014.0138 |
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Rennard SI, Locantore N, Delafont B, Tal-Singer R, Silverman EK, Vestbo J, Miller BE, Bakke P, Celli B, Calverley PM, Coxson H, Crim C, Edwards LD, Lomas DA, MacNee W, et al. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Annals of the American Thoracic Society. 12: 303-12. PMID 25642832 DOI: 10.1513/Annalsats.201403-125Oc |
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Freeman CM, Crudgington S, Stolberg VR, Brown JP, Sonstein J, Alexis NE, Doerschuk CM, Basta PV, Carretta EE, Couper DJ, Hastie AT, Kaner RJ, O'Neal WK, Paine R, Rennard SI, et al. Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Journal of Translational Medicine. 13: 19. PMID 25622723 DOI: 10.1186/S12967-014-0374-Z |
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| 2015 |
Morrow JD, Qiu W, Chhabra D, Rennard SI, Belloni P, Belousov A, Pillai SG, Hersh CP. Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods. Bmc Medical Genomics. 8: 1. PMID 25582225 DOI: 10.1186/S12920-014-0072-Y |
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Ikari J, Smith LM, Nelson AJ, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Feghali-Bostwick C, Liu X, DeMeo DL, Rennard SI. Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro. In Vitro Cellular & Developmental Biology. Animal. 51: 390-9. PMID 25552310 DOI: 10.1007/S11626-014-9820-8 |
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Li YJ, Kanaji N, Wang XQ, Sato T, Nakanishi M, Kim M, Michalski J, Nelson AJ, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI. Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition. Prostaglandins & Other Lipid Mediators. 116: 1-9. PMID 25460827 DOI: 10.1016/J.Prostaglandins.2014.10.003 |
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| 2015 |
Castaldi PJ, Cho MH, Zhou X, Qiu W, Mcgeachie M, Celli B, Bakke P, Gulsvik A, Lomas DA, Crapo JD, Beaty TH, Rennard S, Harshfield B, Lange C, Singh D, et al. Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci. Human Molecular Genetics. 24: 1200-10. PMID 25315895 DOI: 10.1093/Hmg/Ddu525 |
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| 2015 |
Müllerová H, Gelhorn H, Wilson H, Benson V, Karlsson N, Menjoge S, Merrill D, Rennard S, Tal-Singer R, Tabberer M, Jones P. Health status predicts long-term outcomes in patients with chronic obstructive pulmonary disease (COPD): Pooled analysis of patient-level data from the COPD biomarker qualification consortium database European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa3017 |
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| 2015 |
Martinez F, Mannino DM, Leidy NK, Malley KG, Bacci ED, Barr RG, Bowler RP, Han MK, Houfek JF, Make BJ, Meldrum CA, Rennard S, Thomashow BM, Walsh JW, Yawn BP. LATE-BREAKING ABSTRACT: A novel approach for identifying patients with undiagnosed clinically-significant COPD European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa3284 |
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Hanson C, Sayles H, Rutten EEPA, Wouters EFM, MacNee W, Calverley P, Meza JL, Rennard S. The Association Between Dietary Intake and Phenotypical Characteristics of COPD in the ECLIPSE Cohort. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 1: 115-124. PMID 28848815 DOI: 10.15326/Jcopdf.1.1.2014.0113 |
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D'Urzo AD, Rennard SI, Kerwin EM, Mergel V, Leselbaum AR, Caracta CF. Efficacy and safety of fixed-dose combinations of aclidinium bromide/formoterol fumarate: the 24-week, randomized, placebo-controlled AUGMENT COPD study. Respiratory Research. 15: 123. PMID 25756831 DOI: 10.1186/S12931-014-0123-0 |
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| 2014 |
Putcha N, Puhan MA, Drummond MB, Han MK, Regan EA, Hanania NA, Martinez CH, Foreman M, Bhatt SP, Make B, Ramsdell J, DeMeo DL, Barr RG, Rennard SI, Martinez F, et al. A simplified score to quantify comorbidity in COPD. Plos One. 9: e114438. PMID 25514500 DOI: 10.1371/Journal.Pone.0114438 |
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Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, ... ... Rennard SI, et al. Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. Bmc Pulmonary Medicine. 14: 164. PMID 25341556 DOI: 10.1186/1471-2466-14-164 |
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| 2014 |
Carolan BJ, Hughes G, Morrow J, Hersh CP, O'Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne DA, Comellas AP, Han M, Zemans RL, Kechris K, Bowler RP. The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes. Respiratory Research. 15: 127. PMID 25306249 DOI: 10.1186/S12931-014-0127-9 |
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Bhatt SP, Wells JM, Kim V, Criner GJ, Hersh CP, Hardin M, Bailey WC, Nath H, Kim YI, Foreman MG, Stinson DS, Wilson CG, Rennard SI, Silverman EK, Make BJ, et al. Radiological correlates and clinical implications of the paradoxical lung function response to β₂ agonists: an observational study. The Lancet. Respiratory Medicine. 2: 911-8. PMID 25217076 DOI: 10.1016/S2213-2600(14)70185-7 |
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| 2014 |
Murphy L, Rennard S, Donohue J, Molimard M, Dahl R, Beeh KM, Dederichs J, Fülle HJ, Higgins M, Young D. Turning a molecule into a medicine: the development of indacaterol as a novel once-daily bronchodilator treatment for patients with COPD. Drugs. 74: 1635-57. PMID 25212789 DOI: 10.1007/S40265-014-0284-7 |
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Janssen DJ, Müllerova H, Agusti A, Yates JC, Tal-Singer R, Rennard SI, Vestbo J, Wouters EF. Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort. Respiratory Medicine. 108: 1647-54. PMID 25135745 DOI: 10.1016/J.Rmed.2014.07.013 |
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Hanson C, Rutten EP, Wouters EF, Rennard S. Influence of diet and obesity on COPD development and outcomes. International Journal of Chronic Obstructive Pulmonary Disease. 9: 723-33. PMID 25125974 DOI: 10.2147/Copd.S50111 |
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Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR, et al. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Academic Radiology. 21: 1255-61. PMID 25088837 DOI: 10.1016/J.Acra.2014.05.013 |
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| 2014 |
Menche J, Sharma A, Cho MH, Mayer RJ, Rennard SI, Celli B, Miller BE, Locantore N, Tal-Singer R, Ghosh S, Larminie C, Bradley G, Riley JH, Agusti A, Silverman EK, et al. A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease. Bmc Systems Biology. 8: S8. PMID 25032995 DOI: 10.1186/1752-0509-8-S2-S8 |
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Rennard S, Fogarty C, Reisner C, Fernandez C, Fischer T, Golden M, Rose ES, Darken P, Tardie G, Orevillo C. Randomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary disease. Bmc Pulmonary Medicine. 14: 118. PMID 25027304 DOI: 10.1186/1471-2466-14-118 |
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Rennard SI, Sun SX, Tourkodimitris S, Rowe P, Goehring UM, Bredenbröker D, Calverley PM. Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials. International Journal of Chronic Obstructive Pulmonary Disease. 9: 657-73. PMID 25018629 DOI: 10.2147/Copd.S55738 |
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| 2014 |
Kanaji N, Basma H, Nelson A, Farid M, Sato T, Nakanishi M, Wang X, Michalski J, Li Y, Gunji Y, Feghali-Bostwick C, Liu X, Rennard SI. Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L364-73. PMID 25015975 DOI: 10.1152/Ajplung.00041.2014 |
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| 2014 |
Smith BM, Hoffman EA, Rabinowitz D, Bleecker E, Christenson S, Couper D, Donohue KM, Han MK, Hansel NN, Kanner RE, Kleerup E, Rennard S, Barr RG. Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 69: 987-96. PMID 24928812 DOI: 10.1136/Thoraxjnl-2014-205160 |
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Wells JM, O'Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE. An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 190: 51-61. PMID 24874071 DOI: 10.1164/Rccm.201401-0145Oc |
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McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, ... Rennard SI, et al. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 51: 678-87. PMID 24825563 DOI: 10.1165/Rcmb.2014-0135Oc |
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Drummond MB, Buist AS, Crapo JD, Wise RA, Rennard SI. Chronic obstructive pulmonary disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Annals of the American Thoracic Society. 11: S154-60. PMID 24754824 DOI: 10.1513/Annalsats.201312-432Ld |
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| 2014 |
Wang XQ, Mao LJ, Fang QH, Kobayashi T, Kim HJ, Sugiura H, Kawasaki S, Togo S, Kamio K, Liu X, Rennard SI. Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway. Prostaglandins & Other Lipid Mediators. 108: 23-30. PMID 24614064 DOI: 10.1016/J.Prostaglandins.2014.02.002 |
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McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, ... ... Rennard SI, et al. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Annals of the American Thoracic Society. 11: 326-34. PMID 24558953 DOI: 10.1513/Annalsats.201307-229Oc |
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Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, et al. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. American Journal of Respiratory and Critical Care Medicine. 189: 1022-30. PMID 24552242 DOI: 10.1164/Rccm.201311-2006Pp |
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| 2014 |
Basma H, Gunji Y, Iwasawa S, Nelson A, Farid M, Ikari J, Liu X, Wang X, Michalski J, Smith L, Iqbal J, El Behery R, West W, Yelamanchili S, Rennard D, ... ... Rennard SI, et al. Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L552-65. PMID 24487392 DOI: 10.1152/Ajplung.00255.2013 |
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Rennard S, Vestbo J, Agustí A. Reply: correctly defining criteria for diagnosing chronic obstructive pulmonary disease matters. American Journal of Respiratory and Critical Care Medicine. 189: 230-1. PMID 24428653 DOI: 10.1164/Rccm.201307-1396Le |
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O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, ... ... Rennard SI, et al. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. Journal of Translational Medicine. 12: 9. PMID 24397870 DOI: 10.1186/1479-5876-12-9 |
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Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, et al. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax. 69: 666-72. PMID 24310110 DOI: 10.1136/Thoraxjnl-2013-204778 |
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Couper D, LaVange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff PG, Rennard S. Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 69: 491-4. PMID 24029743 DOI: 10.1136/Thoraxjnl-2013-203897 |
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Liu X, Nelson A, Wang X, Farid M, Gunji Y, Ikari J, Iwasawa S, Basma H, Feghali-Bostwick C, Rennard SI. Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 50: 40-50. PMID 23941558 DOI: 10.1165/Rcmb.2013-0211Oc |
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| 2014 |
Tashkin D, Rennard S, Trudo F. Effect of Budesonide/Formoterol or Formoterol on Exacerbation Rates (Including and Excluding Antibiotics) and Responder Analysis: Pooled Analysis of Chronic Obstructive Pulmonary Disease Patients With Moderate vs Severe/Very Severe Airflow Limitation Chest. 146: 74A. DOI: 10.1378/Chest.1990182 |
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| 2014 |
Tashkin D, Rennard S, Trudo F. Effect of Budesonide/Formoterol or Formoterol on Lung Function and Patient-Centered Outcomes: Pooled Analysis of Chronic Obstructive Pulmonary Disease Patients With Moderate vs Severe/Very Severe Airflow Limitation Chest. 146: 31A. DOI: 10.1378/Chest.1990173 |
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| 2014 |
Rennard S, Ferguson G, Kerwin E, Rekeda L, Garcia Gil E. Long-term Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Chest. 146: 69A. DOI: 10.1378/Chest.1959389 |
0.371 |
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| 2014 |
Rabinovich RA, Miller BE, Wrobel K, Choudhury G, Ranjit K, Drost EM, Edwards LD, Lomas DA, Rennard SI, Agusti A, Tal-Singer R, Vestbo J, Wouters E, Beek EV, Murchison JT, et al. S51 Circulating Desmosine Relates To Cardiovascular Comorbidity, Coronary Artery Calcification Score (cacs), Systemic Inflammation And Mortality In Patients With Copd Thorax. 69: A28-A29. DOI: 10.1136/Thoraxjnl-2014-206260.57 |
0.325 |
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| 2013 |
Coxson HO, Dirksen A, Edwards LD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Crim C, Duvoix A, Fauerbach PN, Lomas DA, Macnee W, Mayer RJ, Miller BE, ... ... Rennard SI, et al. The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study. The Lancet. Respiratory Medicine. 1: 129-36. PMID 24429093 DOI: 10.1016/S2213-2600(13)70006-7 |
0.358 |
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| 2013 |
Fang Q, Ma Y, Wang J, Michalski J, Rennard SI, Liu X. PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators of Inflammation. 2013: 145197. PMID 24227907 DOI: 10.1155/2013/145197 |
0.325 |
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| 2013 |
Wang X, Nelson A, Weiler ZM, Patil A, Sato T, Kanaji N, Nakanishi M, Michalski J, Farid M, Basma H, Levan TD, Miller-Larsson A, Wieslander E, Muller KC, Holz O, ... ... Rennard SI, et al. Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2. Journal of Inflammation Research. 6: 109-19. PMID 24062615 DOI: 10.2147/Jir.S43736 |
0.646 |
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| 2013 |
Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustà A, Fabbri LM, ... ... Rennard SI, et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 948-57. PMID 23947473 DOI: 10.1164/Rccm.201302-0247Oc |
0.386 |
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| 2013 |
Rennard S, Thomashow B, Crapo J, Yawn B, McIvor A, Cerreta S, Walsh J, Mannino D. Introducing the COPD foundation guide for diagnosis and management of COPD, recommendations of the COPD foundation Copd: Journal of Chronic Obstructive Pulmonary Disease. 10: 378-389. PMID 23713598 DOI: 10.3109/15412555.2013.801309 |
0.365 |
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| 2013 |
Casaburi R, Celli B, Crapo J, Criner G, Croxton T, Gaw A, Jones P, Kline-Leidy N, Lomas DA, Merrill D, Polkey M, Rennard S, Sciurba F, Tal-Singer R, Stockley R, et al. The COPD biomarker qualification consortium (CBQC) Copd: Journal of Chronic Obstructive Pulmonary Disease. 10: 367-377. PMID 23713597 DOI: 10.3109/15412555.2012.752807 |
0.333 |
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| 2013 |
Hanson C, Rutten EP, Wouters EF, Rennard S. Diet and vitamin D as risk factors for lung impairment and COPD. Translational Research : the Journal of Laboratory and Clinical Medicine. 162: 219-36. PMID 23685188 DOI: 10.1016/J.Trsl.2013.04.004 |
0.36 |
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| 2013 |
D'Urzo A, Kerwin E, Rennard S, He T, Gil EG, Caracta C. One-year extension study of ACCORD COPD I: safety and efficacy of two doses of twice-daily aclidinium bromide in patients with COPD. Copd. 10: 500-10. PMID 23679347 DOI: 10.3109/15412555.2013.791809 |
0.321 |
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| 2013 |
Rennard SI, Vestbo J, Agustí A. What is chronic obstructive pulmonary disease anyway?: Continua, categories, cut points, and moving beyond spirometry. American Journal of Respiratory and Critical Care Medicine. 187: 1036-7. PMID 23675708 DOI: 10.1164/Rccm.201212-2321Ed |
0.379 |
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| 2013 |
Nagahama KY, Togo S, Holz O, Magnussen H, Liu X, Seyama K, Takahashi K, Rennard SI. Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3. American Journal of Respiratory Cell and Molecular Biology. 49: 582-91. PMID 23668543 DOI: 10.1165/Rcmb.2012-0460Oc |
0.338 |
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| 2013 |
Ikari J, Michalski JM, Iwasawa S, Gunji Y, Nogel S, Park JH, Nelson AJ, Farid M, Wang X, Schulte N, Basma H, Toews ML, Feghali-Bostwick C, Tenor H, Liu X, ... Rennard SI, et al. Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2. American Journal of Respiratory Cell and Molecular Biology. 49: 571-81. PMID 23656623 DOI: 10.1165/Rcmb.2013-0004Oc |
0.619 |
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| 2013 |
Farid M, Kanaji N, Nakanishi M, Gunji Y, Michalski J, Iwasawa S, Ikari J, Wang X, Basma H, Nelson AJ, Liu X, Rennard SI. Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts. Toxicology Letters. 220: 126-34. PMID 23618901 DOI: 10.1016/J.Toxlet.2013.04.011 |
0.638 |
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| 2013 |
Kerwin EM, Scott-Wilson C, Sanford L, Rennard S, Agusti A, Barnes N, Crim C. A randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPD. Respiratory Medicine. 107: 560-9. PMID 23352226 DOI: 10.1016/J.Rmed.2012.12.014 |
0.344 |
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| 2013 |
Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, et al. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Human Genetics. 132: 431-41. PMID 23299987 DOI: 10.1007/S00439-012-1262-3 |
0.385 |
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| 2013 |
Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agustà A, Bakke PS, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, et al. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. American Journal of Respiratory and Critical Care Medicine. 187: 382-6. PMID 23262518 DOI: 10.1164/Rccm.201209-1596Oc |
0.375 |
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| 2013 |
Kanaji N, Nelson A, Wang X, Sato T, Nakanishi M, Gunji Y, Basma H, Michalski J, Farid M, Rennard SI, Liu X. Differential roles of JNK, ERK1/2, and p38 mitogen-activated protein kinases on endothelial cell tissue repair functions in response to tumor necrosis factor-α. Journal of Vascular Research. 50: 145-56. PMID 23258237 DOI: 10.1159/000345525 |
0.581 |
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| 2013 |
Rennard SI, Flavin SK, Agarwal PK, Lo KH, Barnathan ES. Long-term safety study of infliximab in moderate-to-severe chronic obstructive pulmonary disease. Respiratory Medicine. 107: 424-32. PMID 23246078 DOI: 10.1016/J.Rmed.2012.11.008 |
0.4 |
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| 2013 |
Sethi S, Mahler DA, Marcus P, Owen CA, Yawn B, Rennard S. Inflammation in COPD: implications for management. The American Journal of Medicine. 125: 1162-70. PMID 23164484 DOI: 10.1016/J.Amjmed.2012.06.024 |
0.404 |
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| 2013 |
Tashkin D, Rennard S, Uryniak T, Martin U, Trudo F. Efficacy Outcomes With Budesonide/Formoterol Pressurized Metered-Dose Inhaler (BUD/FM pMDI) According to Global Initiative for Chronic Obstructive Lung Disease (GOLD) Classification at Baseline in Patients With Chronic Obstructive Pulmonary Disease (COPD) Chest. 144: 729A. DOI: 10.1378/Chest.1703149 |
0.411 |
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| 2012 |
Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustà A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, ... Rennard S, et al. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 186: 1238-47. PMID 23144326 DOI: 10.1164/Rccm.201206-1013Oc |
0.374 |
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| 2012 |
Jen R, Rennard SI, Sin DD. Effects of inhaled corticosteroids on airway inflammation in chronic obstructive pulmonary disease: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease. 7: 587-95. PMID 23055709 DOI: 10.2147/Copd.S32765 |
0.419 |
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| 2012 |
Michalski J, Kanaji N, Liu X, Nogel S, Wang X, Basma H, Nakanishi M, Sato T, Gunji Y, Fahrid M, Nelson A, Muller KC, Holz O, Magnussen H, Rabe KF, ... ... Rennard SI, et al. Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4. American Journal of Respiratory Cell and Molecular Biology. 47: 729-37. PMID 23043089 DOI: 10.1165/Rcmb.2012-0057Oc |
0.412 |
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| 2012 |
Rennard SI, Celli BR. Medical Clinics of North America. Chronic obstructive pulmonary disease. Preface. The Medical Clinics of North America. 96: xi-xii. PMID 22793949 DOI: 10.1016/J.Mcna.2012.05.008 |
0.361 |
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| 2012 |
Albert P, Agusti A, Edwards L, Tal-Singer R, Yates J, Bakke P, Celli BR, Coxson HO, Crim C, Lomas DA, Macnee W, Miller B, Rennard S, Silverman EK, Vestbo J, et al. Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax. 67: 701-8. PMID 22696176 DOI: 10.1136/Thoraxjnl-2011-201458 |
0.419 |
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| 2012 |
Rennard SI, Bailey KL. Chronic obstructive pulmonary disease exacerbations: accurate and easy measurement promises much. American Journal of Respiratory and Critical Care Medicine. 185: 1139-41. PMID 22661519 DOI: 10.1164/Rccm.201202-0227Ed |
0.39 |
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| 2012 |
Agustà A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, Vestbo J, Lomas DA, Calverley PM, Wouters E, Crim C, Yates JC, Silverman EK, Coxson HO, Bakke P, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. Plos One. 7: e37483. PMID 22624038 DOI: 10.1371/Journal.Pone.0037483 |
0.373 |
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| 2012 |
Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agusti A, Anderson W, Lomas DA, Demeo DL. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Human Molecular Genetics. 21: 3073-82. PMID 22492999 DOI: 10.1093/Hmg/Dds135 |
0.303 |
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| 2012 |
Celli BR, Locantore N, Yates J, Tal-Singer R, Miller BE, Bakke P, Calverley P, Coxson H, Crim C, Edwards LD, Lomas DA, Duvoix A, MacNee W, Rennard S, Silverman E, et al. Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 185: 1065-72. PMID 22427534 DOI: 10.1164/Rccm.201110-1792Oc |
0.325 |
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| 2012 |
Loza MJ, Watt R, Baribaud F, Barnathan ES, Rennard SI. Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease. Respiratory Research. 13: 12. PMID 22300528 DOI: 10.1186/1465-9921-13-12 |
0.358 |
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| 2012 |
Nakanishi M, Sato T, Li Y, Nelson AJ, Farid M, Michalski J, Kanaji N, Wang X, Basma H, Patil A, Goraya J, Liu X, Togo S, L Toews M, Holz O, ... ... Rennard SI, et al. Prostaglandin E2 stimulates the production of vascular endothelial growth factor through the E-prostanoid-2 receptor in cultured human lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 46: 217-23. PMID 22298530 DOI: 10.1165/Rcmb.2010-0115Oc |
0.606 |
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| 2012 |
Qiu W, Baccarelli A, Carey VJ, Boutaoui N, Bacherman H, Klanderman B, Rennard S, Agusti A, Anderson W, Lomas DA, DeMeo DL. Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. American Journal of Respiratory and Critical Care Medicine. 185: 373-81. PMID 22161163 DOI: 10.1164/Rccm.201108-1382Oc |
0.389 |
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| 2012 |
Kanaji N, Nelson A, Allen-Gipson DS, Sato T, Nakanishi M, Wang X, Li Y, Basma H, Michalski J, Farid M, Rennard SI, Liu X. The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 61: 233-44. PMID 22138711 DOI: 10.1007/S00011-011-0405-7 |
0.592 |
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| 2012 |
Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, ... ... Rennard S, et al. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Human Molecular Genetics. 21: 947-57. PMID 22080838 DOI: 10.1093/Hmg/Ddr524 |
0.32 |
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| 2012 |
D'Alessandro-Gabazza CN, Kobayashi T, Boveda-Ruiz D, Takagi T, Toda M, Gil-Bernabe P, Miyake Y, Yasukawa A, Matsuda Y, Suzuki N, Saito H, Yano Y, Fukuda A, Hasegawa T, Toyobuku H, ... Rennard SI, et al. Development and preclinical efficacy of novel transforming growth factor-β1 short interfering RNAs for pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 46: 397-406. PMID 22033267 DOI: 10.1165/Rcmb.2011-0158Oc |
0.371 |
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| 2012 |
Spruit MA, Polkey MI, Celli B, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agusti A, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, et al. Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. Journal of the American Medical Directors Association. 13: 291-7. PMID 21778120 DOI: 10.1016/J.Jamda.2011.06.009 |
0.368 |
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| 2011 |
Michalski JM, Golden G, Ikari J, Rennard SI. PDE4: a novel target in the treatment of chronic obstructive pulmonary disease. Clinical Pharmacology and Therapeutics. 91: 134-42. PMID 22130119 DOI: 10.1038/Clpt.2011.266 |
0.398 |
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| 2011 |
Rennard SI, Vestbo J. Republished editorial: hypothesis: in COPD, a pound of cure may be better than an ounce of prevention. Postgraduate Medical Journal. 87: 793-4. PMID 22121250 DOI: 10.1136/Pgmj.2010.151498Rep |
0.406 |
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| 2011 |
Kanaji N, Sato T, Nelson A, Wang X, Li Y, Kim M, Nakanishi M, Basma H, Michalski J, Farid M, Chandler M, Pease W, Patil A, Rennard SI, Liu X. Inflammatory cytokines regulate endothelial cell survival and tissue repair functions via NF-κB signaling. Journal of Inflammation Research. 4: 127-38. PMID 22096375 DOI: 10.2147/Jir.S19461 |
0.6 |
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| 2011 |
Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, MacNee W, Miller BE, Silverman EK, Tal-Singer R, ... ... Rennard SI, et al. Changes in forced expiratory volume in 1 second over time in COPD. The New England Journal of Medicine. 365: 1184-92. PMID 21991892 DOI: 10.1056/Nejmoa1105482 |
0.369 |
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| 2011 |
Qiu W, Cho MH, Riley JH, Anderson WH, Singh D, Bakke P, Gulsvik A, Litonjua AA, Lomas DA, Crapo JD, Beaty TH, Celli BR, Rennard S, Tal-Singer R, Fox SM, et al. Genetics of sputum gene expression in chronic obstructive pulmonary disease. Plos One. 6: e24395. PMID 21949713 DOI: 10.1371/Journal.Pone.0024395 |
0.331 |
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| 2011 |
Martinez FJ, Donohue JF, Rennard SI. The future of chronic obstructive pulmonary disease treatment--difficulties of and barriers to drug development. Lancet (London, England). 378: 1027-37. PMID 21907866 DOI: 10.1016/S0140-6736(11)61047-7 |
0.4 |
|
| 2011 |
Rennard SI. COPD heterogeneity: what this will mean in practice. Respiratory Care. 56: 1181-7. PMID 21801580 DOI: 10.4187/Respcare.01419 |
0.373 |
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| 2011 |
Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, Coxson H, Edwards L, Knobil K, et al. Genome-wide association study of smoking behaviours in patients with COPD Thorax. 66: 894-902. PMID 21685187 DOI: 10.1136/Thoraxjnl-2011-200154 |
0.333 |
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| 2011 |
Celli BR, Tashkin DP, Rennard SI, McElhattan J, Martin UJ. Bronchodilator responsiveness and onset of effect with budesonide/formoterol pMDI in COPD. Respiratory Medicine. 105: 1176-88. PMID 21531124 DOI: 10.1016/J.Rmed.2011.02.020 |
0.395 |
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| 2011 |
Jones PW, Rennard SI, Agusti A, Chanez P, Magnussen H, Fabbri L, Donohue JF, Bateman ED, Gross NJ, Lamarca R, Caracta C, Gil EG. Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. Respiratory Research. 12: 55. PMID 21518460 DOI: 10.1186/1465-9921-12-55 |
0.374 |
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| 2011 |
Sato T, Liu X, Basma H, Togo S, Sugiura H, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Michalski J, Farid M, Sharp JG, Rennard SI. IL-4 induces differentiation of human embryonic stem cells into fibrogenic fibroblast-like cells. The Journal of Allergy and Clinical Immunology. 127: 1595-603.e9. PMID 21388667 DOI: 10.1016/J.Jaci.2011.01.049 |
0.589 |
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| 2011 |
Rennard SI, Vestbo J. Hypothesis: in COPD, a pound of cure may be better than an ounce of prevention. Thorax. 66: 643-5. PMID 21386104 DOI: 10.1136/Thx.2010.151498 |
0.406 |
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| 2011 |
MacNee W, Rennard SI, Hunt JF, Edwards LD, Miller BE, Locantore NW, Tal-Singer R. Evaluation of exhaled breath condensate pH as a biomarker for COPD Respiratory Medicine. 105: 1037-1045. PMID 21377342 DOI: 10.1016/J.Rmed.2011.02.009 |
0.329 |
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| 2011 |
Rennard SI, Calverley PM, Goehring UM, Bredenbröker D, Martinez FJ. Reduction of exacerbations by the PDE4 inhibitor roflumilast--the importance of defining different subsets of patients with COPD. Respiratory Research. 12: 18. PMID 21272339 DOI: 10.1186/1465-9921-12-18 |
0.314 |
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| 2011 |
Castaldi PJ, Demeo DL, Hersh CP, Lomas DA, Soerheim IC, Gulsvik A, Bakke P, Rennard S, Pare P, Vestbo J, Silverman EK. Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. Thorax. 66: 903-9. PMID 21163806 DOI: 10.1136/Thx.2010.146118 |
0.371 |
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| 2011 |
Hanania NA, Müllerova H, Locantore NW, Vestbo J, Watkins ML, Wouters EF, Rennard SI, Sharafkhaneh A. Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort. American Journal of Respiratory and Critical Care Medicine. 183: 604-11. PMID 20889909 DOI: 10.1164/Rccm.201003-0472Oc |
0.375 |
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| 2011 |
Tashkin DP, Rennard S, Hays JT, Ma W, Lawrence D, Lee TC. Effects of varenicline on smoking cessation in patients with mild to moderate COPD: a randomized controlled trial. Chest. 139: 591-9. PMID 20864613 DOI: 10.1378/Chest.10-0865 |
0.341 |
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| 2011 |
Yentes JM, Sayles H, Meza J, Mannino DM, Rennard SI, Stergiou N. Walking abnormalities are associated with COPD: An investigation of the NHANES III dataset. Respiratory Medicine. 105: 80-7. PMID 20615681 DOI: 10.1016/J.Rmed.2010.06.007 |
0.366 |
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| 2011 |
Li YJ, Wang XQ, Sato T, Kanaji N, Nakanishi M, Kim M, Michalski J, Nelson AJ, Sun JH, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI. Prostaglandin Eâ‚‚ inhibits human lung fibroblast chemotaxis through disparate actions on different E-prostanoid receptors. American Journal of Respiratory Cell and Molecular Biology. 44: 99-107. PMID 20203295 DOI: 10.1165/Rcmb.2009-0163Oc |
0.59 |
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| 2011 |
Tashkin D, Celli B, Rennard S, McElhattan J, Martin U. Bronchodilator Responsiveness to Formoterol (FM)-Containing Treatments Based on Measures of Pulmonary Function and Lung Volume in Patients with Chronic Obstructive Pulmonary Disease (COPD) Journal of Allergy and Clinical Immunology. 127: AB223-AB223. DOI: 10.1016/J.Jaci.2010.12.888 |
0.419 |
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| 2010 |
Vestbo J, Rennard S. Chronic Obstructive Pulmonary Disease Biomarker(s) for Disease Activity Needed—Urgently American Journal of Respiratory and Critical Care Medicine. 182: 863-864. PMID 20884938 DOI: 10.1164/Rccm.201004-0602Ed |
0.372 |
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| 2010 |
Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA. Susceptibility to exacerbation in chronic obstructive pulmonary disease. The New England Journal of Medicine. 363: 1128-38. PMID 20843247 DOI: 10.1056/Nejmoa0909883 |
0.405 |
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| 2010 |
Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Agustà A, Calverley PM, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EF, Paré PD, et al. αâ‚-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest. 138: 1125-32. PMID 20595457 DOI: 10.1378/Chest.10-0746 |
0.305 |
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| 2010 |
Singh D, Edwards L, Tal-Singer R, Rennard S. Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study. Respiratory Research. 11: 77. PMID 20550701 DOI: 10.1186/1465-9921-11-77 |
0.353 |
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| 2010 |
Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, MacNee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, et al. Chronic obstructive pulmonary disease phenotypes: The future of COPD American Journal of Respiratory and Critical Care Medicine. 182: 598-604. PMID 20522794 DOI: 10.1164/Rccm.200912-1843Cc |
0.374 |
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| 2010 |
Sato T, Liu X, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Sun J, Michalski J, Patil A, Basma H, Holz O, Magnussen H, Rennard SI. Reduced miR-146a increases prostaglandin E₂in chronic obstructive pulmonary disease fibroblasts. American Journal of Respiratory and Critical Care Medicine. 182: 1020-9. PMID 20522791 DOI: 10.1164/Rccm.201001-0055Oc |
0.399 |
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| 2010 |
Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, ... ... Rennard SI, et al. Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. American Journal of Respiratory and Critical Care Medicine. 182: 605-13. PMID 20463177 DOI: 10.1164/Rccm.200910-1586Oc |
0.307 |
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| 2010 |
Gross NJ, Giembycz MA, Rennard SI. Treatment of chronic obstructive pulmonary disease with roflumilast, a new phosphodiesterase 4 inhibitor. Copd. 7: 141-53. PMID 20397815 DOI: 10.3109/15412551003758304 |
0.397 |
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| 2010 |
Chandler MA, Rennard SI. Smoking cessation. Chest. 137: 428-35. PMID 20133289 DOI: 10.1378/Chest.09-0124 |
0.334 |
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| 2010 |
Nicholas BL, Skipp P, Barton S, Singh D, Bagmane D, Mould R, Angco G, Ward J, Guha-Niyogi B, Wilson S, Howarth P, Davies DE, Rennard S, O'Connor CD, Djukanovic R. Identification of lipocalin and apolipoprotein A1 as biomarkers of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 181: 1049-60. PMID 20110559 DOI: 10.1164/Rccm.200906-0857Oc |
0.394 |
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| 2010 |
Simet SM, Sisson JH, Pavlik JA, Devasure JM, Boyer C, Liu X, Kawasaki S, Sharp JG, Rennard SI, Wyatt TA. Long-term cigarette smoke exposure in a mouse model of ciliated epithelial cell function. American Journal of Respiratory Cell and Molecular Biology. 43: 635-40. PMID 20042711 DOI: 10.1165/Rcmb.2009-0297Oc |
0.324 |
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| 2010 |
Tashkin D, Celli B, Rennard S, McElhattan J, Martin U. Bronchodilator Responsiveness to Formoterol (FM)-Containing Treatments by Chronic Obstructive Pulmonary Disease (COPD) Severity Classification Journal of Allergy and Clinical Immunology. 125: AB66. DOI: 10.1016/J.Jaci.2009.12.259 |
0.398 |
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| 2009 |
Bateman ED, Rennard S, Barnes PJ, Dicpinigaitis PV, Gosens R, Gross NJ, Nadel JA, Pfeifer M, Racké K, Rabe KF, Rubin BK, Welte T, Wessler I. Alternative mechanisms for tiotropium. Pulmonary Pharmacology & Therapeutics. 22: 533-42. PMID 19635581 DOI: 10.1016/J.Pupt.2009.06.002 |
0.366 |
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| 2009 |
Sugiura H, Liu X, Ichikawa T, Ichinose M, Rennard SI. 3-Nitrotyrosine inhibits fibroblast-mediated collagen gel contraction and chemotaxis. The European Respiratory Journal. 34: 1452-60. PMID 19443526 DOI: 10.1183/09031936.00195808 |
0.306 |
|
| 2009 |
Sugiura H, Ichikawa T, Liu X, Kobayashi T, Wang XQ, Kawasaki S, Togo S, Kamio K, Mao L, Ann Y, Ichinose M, Rennard SI. N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts. Pulmonary Pharmacology & Therapeutics. 22: 487-91. PMID 19393328 DOI: 10.1016/J.Pupt.2009.04.002 |
0.351 |
|
| 2009 |
Rennard SI, Tashkin DP, McElhattan J, Goldman M, Ramachandran S, Martin UJ, Silkoff PE. Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial. Drugs. 69: 549-65. PMID 19368417 DOI: 10.2165/00003495-200969050-00004 |
0.385 |
|
| 2009 |
Barr RG, Celli BR, Mannino DM, Petty T, Rennard SI, Sciurba FC, Stoller JK, Thomashow BM, Turino GM. Comorbidities, patient knowledge, and disease management in a national sample of patients with COPD. The American Journal of Medicine. 122: 348-55. PMID 19332230 DOI: 10.1016/J.Amjmed.2008.09.042 |
0.351 |
|
| 2009 |
Togo S, Liu X, Wang X, Sugiura H, Kamio K, Kawasaki S, Kobayashi T, Ertl RF, Ahn Y, Holz O, Magnussen H, Fredriksson K, Skold CM, Rennard SI. PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L959-69. PMID 19304913 DOI: 10.1152/Ajplung.00508.2007 |
0.302 |
|
| 2009 |
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, et al. A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. Plos Genetics. 5: e1000421. PMID 19300482 DOI: 10.1371/Journal.Pgen.1000421 |
0.352 |
|
| 2009 |
Kikuchi K, Kohyama T, Yamauchi Y, Kato J, Takami K, Okazaki H, Desaki M, Nagase T, Rennard SI, Takizawa H. C-reactive protein modulates human lung fibroblast migration. Experimental Lung Research. 35: 48-58. PMID 19191104 DOI: 10.1080/01902140802404138 |
0.34 |
|
| 2009 |
DeMeo DL, Campbell EJ, Brantly ML, Barker AF, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Silverman EK. Heritability of lung function in severe alpha-1 antitrypsin deficiency. Human Heredity. 67: 38-45. PMID 18931508 DOI: 10.1159/000164397 |
0.302 |
|
| 2009 |
Rennard SI, Tashkin DP, McElhattan J, Martin UJ. EFFECT OF BUDESONIDE/FORMOTEROL PRESSURIZED METERED-DOSE INHALER BY AGE GROUP ON FORCED EXPIRATORY VOLUME IN 1 SECOND IN PATIENTS WITH MODERATE TO VERY SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE Chest. 136: 95S. DOI: 10.1378/Chest.136.4_Meetingabstracts.95S |
0.361 |
|
| 2008 |
Rennard S, Knobil K, Rabe KF, Morris A, Schachter N, Locantore N, Canonica WG, Zhu Y, Barnhart F. The Efficacy and Safety of Cilomilast in COPD Drugs. 68: 3-57. PMID 19105585 DOI: 10.2165/0003495-200868002-00002 |
0.363 |
|
| 2008 |
Calverley PM, Rennard S, Nelson HS, Karpel JP, Abbate EH, Stryszak P, Staudinger H. One-year treatment with mometasone furoate in chronic obstructive pulmonary disease. Respiratory Research. 9: 73. PMID 19014549 DOI: 10.1186/1465-9921-9-73 |
0.373 |
|
| 2008 |
Liu X, Togo S, Al-Mugotir M, Kim H, Fang Q, Kobayashi T, Wang X, Mao L, Bitterman P, Rennard S. NF-kappaB mediates the survival of human bronchial epithelial cells exposed to cigarette smoke extract. Respiratory Research. 9: 66. PMID 18811964 DOI: 10.1186/1465-9921-9-66 |
0.312 |
|
| 2008 |
Rennard SI, Vestbo J. The many "small COPDs": COPD should be an orphan disease. Chest. 134: 623-627. PMID 18779197 DOI: 10.1378/Chest.07-3059 |
0.386 |
|
| 2008 |
Tashkin DP, Rennard SI, Martin P, Ramachandran S, Martin UJ, Silkoff PE, Goldman M. Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial. Drugs. 68: 1975-2000. PMID 18778120 DOI: 10.2165/00003495-200868140-00004 |
0.33 |
|
| 2008 |
Decramer M, Rennard S, Troosters T, Mapel DW, Giardino N, Mannino D, Wouters E, Sethi S, Cooper CB. COPD as a lung disease with systemic consequences--clinical impact, mechanisms, and potential for early intervention. Copd. 5: 235-56. PMID 18671149 DOI: 10.1080/15412550802237531 |
0.398 |
|
| 2008 |
Cazzola M, Hanania NA, Jones PW, Mahler DA, Make B, Ohar J, Rennard S. It's about time: directing our attention toward modifying the course of COPD Respiratory Medicine. 102: 37-48. PMID 18582796 DOI: 10.1016/S0954-6111(08)70006-4 |
0.386 |
|
| 2008 |
Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, et al. Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 178: 500-5. PMID 18565956 DOI: 10.1164/Rccm.200801-059Oc |
0.403 |
|
| 2008 |
Togo S, Holz O, Liu X, Sugiura H, Kamio K, Wang X, Kawasaki S, Ahn Y, Fredriksson K, Skold CM, Mueller KC, Branscheid D, Welker L, Watz H, Magnussen H, ... Rennard SI, et al. Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms. American Journal of Respiratory and Critical Care Medicine. 178: 248-60. PMID 18467512 DOI: 10.1164/Rccm.200706-929Oc |
0.418 |
|
| 2008 |
Kamio K, Sato T, Liu X, Sugiura H, Togo S, Kobayashi T, Kawasaki S, Wang X, Mao L, Ahn Y, Holz O, Magnussen H, Rennard SI. Prostacyclin analogs stimulate VEGF production from human lung fibroblasts in culture. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1226-32. PMID 18424619 DOI: 10.1152/Ajplung.00129.2007 |
0.345 |
|
| 2008 |
Fang Q, Mao L, Kobayashi T, Wang X, Wyatt TA, Kim H, Liu X, Rennard SI. PKCdelta mediates thrombin-augmented fibroblast-mediated collagen gel contraction. Biochemical and Biophysical Research Communications. 369: 1199-203. PMID 18342628 DOI: 10.1016/J.Bbrc.2008.03.016 |
0.314 |
|
| 2008 |
Demeo DL, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Silverman EK. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. American Journal of Respiratory Cell and Molecular Biology. 38: 114-20. PMID 17690329 DOI: 10.1165/Rcmb.2007-0107Oc |
0.34 |
|
| 2008 |
Nelson HS, Tashkin DP, Rennard SI, Martin P, Goldman M, Silkoff PE. ONSET OF BRONCHODILATION WITH BUDESONIDE AND FORMOTEROL ADMINISTERED IN ONE PRESSURIZED METERED-DOSE INHALER IN PATIENTS WITH MODERATE TO VERY SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE Chest. 134: 105P. DOI: 10.1378/Chest.134.4_Meetingabstracts.P105002 |
0.373 |
|
| 2008 |
Rennard SI, Tashkin DP, McElhattan J, Goldman M, Silkoff PE. LONG-TERM TOLERABILITY OF BUDESONIDE AND FORMOTEROL ADMINISTERED IN ONE PRESSURIZED METERED-DOSE INHALER IN PATIENTS WITH MODERATE TO VERY SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE Chest. 134: 103P. DOI: 10.1378/Chest.134.4_Meetingabstracts.P103003 |
0.36 |
|
| 2008 |
Rennard SI, Tashkin DP, McElhattan J, Goldman M, Silkoff PE. LONG-TERM EFFICACY OF BUDESONIDE/FORMOTEROL ADMINISTERED VIA ONE PRESSURIZED METERED-DOSE INHALER IN PATIENTS WITH MODERATE TO VERY SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE Chest. 134: 103P. DOI: 10.1378/Chest.134.4_Meetingabstracts.P103001 |
0.361 |
|
| 2008 |
Wyatt TA, Schmidt SC, Rennard SI, Tuma DJ, Sisson JH. Acetaldehyde-Stimulated PKC Activity in Airway Epithelial Cells Treated with Smoke Extract from Normal and Smokeless Cigarettes Proceedings of the Society For Experimental Biology and Medicine. 225: 91-97. DOI: 10.1111/J.1525-1373.2000.22511.X |
0.32 |
|
| 2008 |
BERRO A, BOYER C, ANDERSON D, KAWASAKI S, PERRY G, SWANSON P, RENNARD S, CASALE T. Effects of Prenatal Smoke and Nicotine Exposure on Airway Responsiveness and Inflammation in a Murine Model of Allergic Asthma Journal of Allergy and Clinical Immunology. 121: S235-S235. DOI: 10.1016/J.Jaci.2007.12.928 |
0.312 |
|
| 2007 |
Ohnishi T, Arnold LL, He J, Clark NM, Kawasaki S, Rennard SI, Boyer CW, Cohen SM. Inhalation of tobacco smoke induces increased proliferation of urinary bladder epithelium and endothelium in female C57BL/6 mice. Toxicology. 241: 58-65. PMID 17897767 DOI: 10.1016/J.Tox.2007.08.088 |
0.31 |
|
| 2007 |
Calverley PMA, Rennard SI. What have we learned from large drug treatment trials in COPD The Lancet. 370: 774-785. PMID 17765527 DOI: 10.1016/S0140-6736(07)61381-6 |
0.359 |
|
| 2007 |
Sugiura H, Liu X, Duan F, Kawasaki S, Togo S, Kamio K, Wang XQ, Mao L, Ahn Y, Ertl RF, Bargar TW, Berro A, Casale TB, Rennard SI. Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal. American Journal of Respiratory Cell and Molecular Biology. 37: 424-30. PMID 17575074 DOI: 10.1165/Rcmb.2007-0089Oc |
0.331 |
|
| 2007 |
Demeo DL, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard S, Burchard E, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Silverman EK. Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax. 62: 806-13. PMID 17389752 DOI: 10.1136/Thx.2006.075846 |
0.364 |
|
| 2007 |
Liu X, Das AM, Seideman J, Griswold D, Afuh CN, Kobayashi T, Abe S, Fang Q, Hashimoto M, Kim H, Wang X, Shen L, Kawasaki S, Rennard SI. The CC chemokine ligand 2 (CCL2) mediates fibroblast survival through IL-6. American Journal of Respiratory Cell and Molecular Biology. 37: 121-8. PMID 17379849 DOI: 10.1165/Rcmb.2005-0253Oc |
0.311 |
|
| 2007 |
Kamio K, Liu X, Sugiura H, Togo S, Kobayashi T, Kawasaki S, Wang X, Mao L, Ahn Y, Hogaboam C, Toews ML, Rennard SI. Prostacyclin analogs inhibit fibroblast contraction of collagen gels through the cAMP-PKA pathway. American Journal of Respiratory Cell and Molecular Biology. 37: 113-20. PMID 17363776 DOI: 10.1165/Rcmb.2007-0009Oc |
0.304 |
|
| 2007 |
Rennard SI, Fogarty C, Kelsen S, Long W, Ramsdell J, Allison J, Mahler D, Saadeh C, Siler T, Snell P, Korenblat P, Smith W, Kaye M, Mandel M, Andrews C, et al. The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 175: 926-34. PMID 17290043 DOI: 10.1164/Rccm.200607-995Oc |
0.403 |
|
| 2007 |
Sugiura H, Liu X, Togo S, Kobayashi T, Shen L, Kawasaki S, Kamio K, Wang XQ, Mao LJ, Rennard SI. Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation. Journal of Cellular Physiology. 210: 99-110. PMID 16998801 DOI: 10.1002/Jcp.20825 |
0.315 |
|
| 2006 |
Kim H, Liu X, Kohyama T, Kobayashi T, Conner H, Abe S, Fang Q, Wen FQ, Rennard SI. Cigarette smoke stimulates MMP-1 production by human lung fibroblasts through the ERK1/2 pathway. Copd. 1: 13-23. PMID 16997735 DOI: 10.1081/Copd-120030164 |
0.317 |
|
| 2006 |
Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 8: 600-22. PMID 16920658 DOI: 10.1080/14622200600858166 |
0.324 |
|
| 2006 |
Rennard SI, Glover ED, Leischow S, Daughton DM, Glover PN, Muramoto M, Franzon M, Danielsson T, Landfeldt B, Westin A. Efficacy of the nicotine inhaler in smoking reduction: A double-blind, randomized trial. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 8: 555-64. PMID 16920653 DOI: 10.1080/14622200600789916 |
0.31 |
|
| 2006 |
Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 8: 169-91. PMID 16766411 DOI: 10.1080/14622200600576628 |
0.324 |
|
| 2006 |
Kapoun AM, Gaspar NJ, Wang Y, Damm D, Liu YW, O'young G, Quon D, Lam A, Munson K, Tran TT, Ma JY, Murphy A, Dugar S, Chakravarty S, Protter AA, ... ... Rennard SI, et al. Transforming growth factor-beta receptor type 1 (TGFbetaRI) kinase activity but not p38 activation is required for TGFbetaRI-induced myofibroblast differentiation and profibrotic gene expression. Molecular Pharmacology. 70: 518-31. PMID 16707625 DOI: 10.1124/Mol.105.021600 |
0.386 |
|
| 2006 |
Rennard SI. Chronic obstructive pulmonary disease: linking outcomes and pathobiology of disease modification. Proceedings of the American Thoracic Society. 3: 276-80. PMID 16636098 DOI: 10.1513/PATS.200512-129SF |
0.333 |
|
| 2006 |
Rennard SI, Vestbo J. COPD: the dangerous underestimate of 15% The Lancet. 367: 1216-1219. PMID 16631861 DOI: 10.1016/S0140-6736(06)68516-4 |
0.389 |
|
| 2006 |
Rennard SI, Schachter N, Strek M, Rickard K, Amit O. Cilomilast for COPD: results of a 6-month, placebo-controlled study of a potent, selective inhibitor of phosphodiesterase 4. Chest. 129: 56-66. PMID 16424413 DOI: 10.1378/Chest.129.1.56 |
0.34 |
|
| 2006 |
Sugiura H, Liu X, Kobayashi T, Togo S, Ertl RF, Kawasaki S, Kamio K, Wang XQ, Mao L, Shen L, Hogaboam CM, Rennard SI. Reactive nitrogen species augment fibroblast-mediated collagen gel contraction, mediator production, and chemotaxis. American Journal of Respiratory Cell and Molecular Biology. 34: 592-9. PMID 16399954 DOI: 10.1165/Rcmb.2005-0339Oc |
0.312 |
|
| 2006 |
Barr RG, Celli BR, Martinez FJ, Ries AL, Rennard SI, Reilly JJ, Sciurba FC, Thomashow BM, Wise RA. Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey. The American Journal of Medicine. 118: 1415. PMID 16378794 DOI: 10.1016/J.Amjmed.2005.07.059 |
0.36 |
|
| 2005 |
Celli BR, Calverley PM, Rennard SI, Wouters EF, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Proposal for a multidimensional staging system for chronic obstructive pulmonary disease. Respiratory Medicine. 99: 1546-54. PMID 16291077 DOI: 10.1016/J.Rmed.2005.03.019 |
0.37 |
|
| 2005 |
Kato J, Kohyama T, Okazaki H, Desaki M, Nagase T, Rennard SI, Takizawa H. Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts. Clinical Immunology (Orlando, Fla.). 117: 177-81. PMID 16109507 DOI: 10.1016/J.Clim.2005.07.003 |
0.346 |
|
| 2005 |
Spurzem JR, Rennard SI. Pathogenesis of COPD. Seminars in Respiratory and Critical Care Medicine. 26: 142-53. PMID 16088433 DOI: 10.1055/S-2005-869535 |
0.439 |
|
| 2004 |
Reid J, Price D, van der Molen T, Housset B, Jardim J, Jones P, Kardos P, Muir JF, Paggiaro P, Rennard S, Wouters E. Development of a primary-care tool to assess treatment success in COPD: consensus report from a closed meeting of respiratory and primary-care specialists. Primary Care Respiratory Journal : Journal of the General Practice Airways Group. 13: 99-104. PMID 16701649 DOI: 10.1016/J.Pcrj.2004.03.002 |
0.349 |
|
| 2004 |
Watson L, Vestbo J, Postma DS, Decramer M, Rennard S, Kiri VA, Vermeire PA, Soriano JB. Gender differences in the management and experience of Chronic Obstructive Pulmonary Disease. Respiratory Medicine. 98: 1207-1213. PMID 15588042 DOI: 10.1016/J.Rmed.2004.05.004 |
0.312 |
|
| 2004 |
Rennard SI. Cigarette smoke in research. American Journal of Respiratory Cell and Molecular Biology. 31: 479-80. PMID 15494467 DOI: 10.1165/Rcmb.F284 |
0.309 |
|
| 2004 |
Ohta K, Fukuchi Y, Grouse L, Mizutani R, Rabe KF, Rennard SI, Zhong NS. A prospective clinical study of theophylline safety in 3810 elderly with asthma or COPD. Respiratory Medicine. 98: 1016-24. PMID 15481279 DOI: 10.1016/J.Rmed.2004.02.020 |
0.33 |
|
| 2004 |
Rennard SI. Treatment of stable chronic obstructive pulmonary disease The Lancet. 364: 791-802. PMID 15337408 DOI: 10.1016/S0140-6736(04)16941-9 |
0.409 |
|
| 2004 |
Rennard SI. Looking at the patient--approaching the problem of COPD. The New England Journal of Medicine. 350: 965-6. PMID 14999106 DOI: 10.1056/Nejmp048022 |
0.385 |
|
| 2004 |
Leidy NK, Rennard SI, Schmier J, Jones MK, Goldman M. The breathlessness, cough, and sputum scale: the development of empirically based guidelines for interpretation. Chest. 124: 2182-91. PMID 14665499 DOI: 10.1378/Chest.124.6.2182 |
0.314 |
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| 2003 |
Gamble E, Grootendorst DC, Brightling CE, Troy S, Qiu Y, Zhu J, Parker D, Matin D, Majumdar S, Vignola AM, Kroegel C, Morell F, Hansel TT, Rennard SI, Compton C, et al. Antiinflammatory Effects of the Phosphodiesterase-4 Inhibitor Cilomilast (Ariflo) in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. 168: 976-982. PMID 12816740 DOI: 10.1164/Rccm.200212-1490Oc |
0.351 |
|
| 2003 |
Rennard SI. Pathogenesis of COPD. Clinical Cornerstone. 5: 11-6. PMID 12739307 DOI: 10.1016/S1098-3597(03)90004-4 |
0.375 |
|
| 2003 |
Liu X, Kohyama T, Kobayashi T, Abe S, Kim HJ, Reed EC, Rennard SI. Cigarette smoke extract inhibits chemotaxis and collagen gel contraction mediated by human bone marrow osteoprogenitor cells and osteoblast-like cells. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 14: 235-42. PMID 12730796 DOI: 10.1007/S00198-002-1350-7 |
0.327 |
|
| 2003 |
Rennard SI. COPD: treatments benefit patients. The Lancet. 361: 444-445. PMID 12583937 DOI: 10.1016/S0140-6736(03)12467-1 |
0.308 |
|
| 2003 |
Kim H, Liu X, Kobayashi T, Kohyama T, Wen FQ, Romberger DJ, Conner H, Gilmour PS, Donaldson K, MacNee W, Rennard SI. Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction. American Journal of Respiratory Cell and Molecular Biology. 28: 111-21. PMID 12495939 DOI: 10.1165/Rcmb.4796 |
0.318 |
|
| 2003 |
Rennard S, Decramer M, Calverley PM, Pride NB, Soriano JB, Vermeire PA, Vestbo J. Impact of COPD in North America and Europe in 2000: subjects' perspective of Confronting COPD International Survey. The European Respiratory Journal. 20: 799-805. PMID 12412667 DOI: 10.1183/09031936.02.03242002 |
0.355 |
|
| 2003 |
Wang H, Liu X, Umino T, Kohyama T, Zhu YK, Wen FQ, Spurzem JR, Romberger DJ, Kim HJ, Rennard SI. Effect of cigarette smoke on fibroblast-mediated gel contraction is dependent on cell density. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L205-13. PMID 12388358 DOI: 10.1152/Ajplung.00042.2002 |
0.311 |
|
| 2002 |
Rennard SI, Umino T, Millatmal T, Daughton DM, Manouilova LS, Ullrich FA, Patil KD, Romberger DJ, Floreani AA, Anderson JR. Evaluation of subclinical respiratory tract inflammation in heavy smokers who switch to a cigarette-like nicotine delivery device that primarily heats tobacco Nicotine and Tobacco Research. 4: 467-476. PMID 12521406 DOI: 10.1080/1462220021000018407 |
0.309 |
|
| 2002 |
Kohyama T, Wyatt TA, Liu X, Wen FQ, Kobayashi T, Fang Q, Kim HJ, Rennard SI. PGD(2) modulates fibroblast-mediated native collagen gel contraction. American Journal of Respiratory Cell and Molecular Biology. 27: 375-81. PMID 12204901 DOI: 10.1165/Rcmb.4830 |
0.304 |
|
| 2002 |
Kim HJ, Liu X, Wang H, Kohyama T, Kobayashi T, Wen FQ, Romberger DJ, Abe S, MacNee W, Rahman I, Rennard SI. Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L409-17. PMID 12114203 DOI: 10.1152/Ajplung.00059.2002 |
0.331 |
|
| 2002 |
Rennard SI. Overview of causes of COPD. New understanding of pathogenesis and mechanisms can guide future therapy. Postgraduate Medicine. 111: 28-30, 33-4, 37-8. PMID 12082919 DOI: 10.3810/Pgm.2002.06.1223 |
0.351 |
|
| 2002 |
Toews ML, Ediger TL, Romberger DJ, Rennard SI. Lysophosphatidic acid in airway function and disease. Biochimica Et Biophysica Acta. 1582: 240-50. PMID 12069834 DOI: 10.1016/S1388-1981(02)00177-4 |
0.368 |
|
| 2002 |
Kohyama T, Liu X, Wen FQ, Zhu YK, Wang H, Kim HJ, Takizawa H, Cieslinski LB, Barnette MS, Rennard SI. PDE4 inhibitors attenuate fibroblast chemotaxis and contraction of native collagen gels. American Journal of Respiratory Cell and Molecular Biology. 26: 694-701. PMID 12034568 DOI: 10.1165/Ajrcmb.26.6.4743 |
0.313 |
|
| 2002 |
Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1049-56. PMID 11943670 DOI: 10.1152/Ajplung.00321.2001 |
0.332 |
|
| 2002 |
Rennard SI. New therapeutic drugs in the management of chronic obstructive pulmonary disease. Current Opinion in Pulmonary Medicine. 8: 106-11. PMID 11845005 DOI: 10.1097/00063198-200203000-00005 |
0.39 |
|
| 2002 |
Wang H, Liu X, Umino T, Sköld CM, Zhu Y, Kohyama T, Spurzem JR, Romberger DJ, Rennard SI. Cigarette smoke inhibits human bronchial epithelial cell repair processes. American Journal of Respiratory Cell and Molecular Biology. 25: 772-9. PMID 11726404 DOI: 10.1165/Ajrcmb.25.6.4458 |
0.393 |
|
| 2001 |
Zhu YK, Liu X, Wang H, Kohyama T, Wen FQ, Sköld CM, Rennard SI. Interactions between monocytes and smooth-muscle cells can lead to extracellular matrix degradation. The Journal of Allergy and Clinical Immunology. 108: 989-96. PMID 11742278 DOI: 10.1067/Mai.2001.120193 |
0.348 |
|
| 2001 |
Kohyama T, Ertl RF, Valenti V, Spurzem J, Kawamoto M, Nakamura Y, Veys T, Allegra L, Romberger D, Rennard SI. Prostaglandin E(2) inhibits fibroblast chemotaxis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L1257-63. PMID 11597918 DOI: 10.1152/Ajplung.2001.281.5.L1257 |
0.314 |
|
| 2001 |
Johnson M, Rennard S. Alternative mechanisms for long-acting beta(2)-adrenergic agonists in COPD. Chest. 120: 258-70. PMID 11451847 DOI: 10.1378/Chest.120.1.258 |
0.324 |
|
| 2001 |
Mio T, Liu X, Toews ML, Adachi Y, Romberger DJ, Spurzem JR, Rennard SI. Bradykinin augments fibroblast-mediated contraction of released collagen gels American Journal of Physiology - Lung Cellular and Molecular Physiology. 281. PMID 11404259 DOI: 10.1152/Ajplung.2001.281.1.L164 |
0.33 |
|
| 2001 |
Rennard SI, Anderson W, ZuWallack R, Broughton J, Bailey W, Friedman M, Wisniewski M, Rickard K. Use of a long-acting inhaled beta2-adrenergic agonist, salmeterol xinafoate, in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 163: 1087-92. PMID 11316640 DOI: 10.1164/Ajrccm.163.5.9903053 |
0.381 |
|
| 2001 |
Polosukhin VV, Manouilova LS, Romberger DJ, Matthews KI, Pirruccello SJ, West W, Daughton DM, Millatmal T, Umino T, Rennard SI. Ultrastructural heterogeneity of the alveolar macrophages from tobacco smokers with chronic bronchitis. Ultrastructural Pathology. 25: 5-11. PMID 11297319 DOI: 10.1080/019131201300004636 |
0.334 |
|
| 2001 |
Rennard S, Carrera M, Agustí AG. Management of chronic obstructive pulmonary disease: are we going anywhere? The European Respiratory Journal. 16: 1035-6. PMID 11292101 DOI: 10.1034/J.1399-3003.2000.16F02.X |
0.369 |
|
| 2001 |
Rennard SI. Epithelial cells and fibroblasts. Novartis Foundation Symposium. 234: 104-119. DOI: 10.1002/0470868678.Ch7 |
0.39 |
|
| 2000 |
Pineda R, Rennard SI. Anticholinergic bronchodilators in combination. Expert Opinion On Pharmacotherapy. 1: 1281-1287. PMID 11249465 DOI: 10.1517/14656566.1.7.1281 |
0.382 |
|
| 2000 |
Liu Xd, Umino T, Zhu YK, Wang H, Spurzem JR, Romberger DJ, Rennard SI. A study on the effect of cadmium on human lung fibroblasts Chest. 117: 247S. PMID 10843933 DOI: 10.1016/S0012-3692(15)51014-3 |
0.322 |
|
| 2000 |
Rennard SI, Romberger DJ. Host defenses and pathogenesis. Seminars in Respiratory Infections. 15: 7-13. PMID 10749545 DOI: 10.1053/Srin.2000.0150007 |
0.304 |
|
| 1999 |
Floreani AA, Rennard SI. The role of cigarette smoke in the pathogenesis of asthma and as a trigger for acute symptoms. Current Opinion in Pulmonary Medicine. 5: 38-46. PMID 10813248 DOI: 10.1097/00063198-199901000-00007 |
0.303 |
|
| 1999 |
Rennard SI. Inflammation and repair processes in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 160: S12-6. PMID 10556162 DOI: 10.1164/Ajrccm.160.Supplement_1.5 |
0.395 |
|
| 1999 |
Fujita J, Sköld CM, Daughton DM, Ertl RF, Takahara J, Rennard SI. Modulation of elastase binding to elastin by human alveolar macrophage-derived lipids. American Journal of Respiratory and Critical Care Medicine. 160: 802-7. PMID 10471600 DOI: 10.1164/Ajrccm.160.3.9806047 |
0.318 |
|
| 1999 |
Sköld CM, Liu X, Umino T, Zhu Y, Ohkuni Y, Romberger DJ, Spurzem JR, Heires AJ, Rennard SI. Human neutrophil elastase augments fibroblast-mediated contraction of released collagen gels. American Journal of Respiratory and Critical Care Medicine. 159: 1138-46. PMID 10194158 DOI: 10.1164/Ajrccm.159.4.9805033 |
0.325 |
|
| 1998 |
Mio T, Liu XD, Adachi Y, Striz I, Sköld CM, Romberger DJ, Spurzem JR, Illig MG, Ertl R, Rennard SI. Human bronchial epithelial cells modulate collagen gel contraction by fibroblasts. American Journal of Physiology. Lung Cellular and Molecular Physiology. 274: L119-L126. PMID 29586258 DOI: 10.1152/Ajplung.1998.274.1.L119 |
0.331 |
|
| 1998 |
Rennard SI. COPD: overview of definitions, epidemiology, and factors influencing its development. Chest. 113: 235S-241S. PMID 9552012 DOI: 10.1378/Chest.113.4_Supplement.235S |
0.351 |
|
| 1998 |
Rennard SI. Repair of the airway epithelium: Potential opportunities for therapeutic intervention in airway disease Allergology International. 47: 91-97. DOI: 10.2332/Allergolint.47.91 |
0.321 |
|
| 1998 |
ANZUETO A, JUBRAN A, OHAR JA, PIQUETTE CA, RENNARD SI, COLICE G, PATTISHALL EN, BARRETT J, ENGLE M, PERRET KA, RUBIN BK. Effects of Aerosolized Surfactant in Patients with Stable Chronic Bronchitis Survey of Anesthesiology. 42: 304. DOI: 10.1097/00132586-199810000-00058 |
0.309 |
|
| 1997 |
Robbins RA, Millatmal T, Lassi K, Rennard S, Daughton D. Smoking Cessation Is Associated With an Increase in Exhaled Nitric Oxide Chest. 112: 313-318. PMID 9266863 DOI: 10.1378/Chest.112.2.313 |
0.306 |
|
| 1997 |
Mio T, Romberger DJ, Thompson AB, Robbins RA, Heires A, Rennard SI. Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine. 155: 1770-6. PMID 9154890 DOI: 10.1164/Ajrccm.155.5.9154890 |
0.336 |
|
| 1997 |
Floreani AA, Rennard SI. Experimental treatments for asthma. Current Opinion in Pulmonary Medicine. 3: 30-41. PMID 9139770 DOI: 10.1097/00063198-199701000-00006 |
0.307 |
|
| 1997 |
Spurzem JR, Rennard SI, Romberger DJ. Bombesin-like peptides and airway repair: a recapitulation of lung development? American Journal of Respiratory Cell and Molecular Biology. 16: 209-11. PMID 9070603 DOI: 10.1165/Ajrcmb.16.3.9070603 |
0.341 |
|
| 1997 |
Rennard SI. Repair mechanisms in asthma. The Journal of Allergy and Clinical Immunology. 98: S278-86. PMID 8977537 DOI: 10.1016/S0091-6749(96)70076-3 |
0.307 |
|
| 1996 |
Hill GE, Pohorecki R, Alonso A, Rennard SI, Robbins RA. Aprotinin reduces interleukin-8 production and lung neutrophil accumulation after cardiopulmonary bypass Anesthesia & Analgesia. 83: 696-700. PMID 8831305 DOI: 10.1097/00000539-199610000-00006 |
0.332 |
|
| 1996 |
Rennard SI, Serby CW, Ghafouri M, Johnson PA, Friedman M. Extended therapy with ipratropium is associated with improved lung function in patients with COPD. A retrospective analysis of data from seven clinical trials. Chest. 110: 62-70. PMID 8681667 DOI: 10.1378/Chest.110.1.62 |
0.307 |
|
| 1996 |
Ito H, Rennard SI, Spurzem JR. Mononuclear cell conditioned medium enhances bronchial epithelial cell migration but inhibits attachment to fibronectin. The Journal of Laboratory and Clinical Medicine. 127: 494-503. PMID 8621987 DOI: 10.1016/S0022-2143(96)90067-0 |
0.309 |
|
| 1996 |
Levin DC, Little KS, Laughlin KR, Galbraith JM, Gustman PM, Murphy D, Kram JA, Hardie G, Reuter C, Ostransky D, McFarland K, Petty TL, Silvers W, Rennard SI, Mueller M, et al. Addition of anticholinergic solution prolongs bronchodilator effect of β2 agonists in patients with chronic obstructive pulmonary disease American Journal of Medicine. 100. PMID 8610716 DOI: 10.1016/S0002-9343(96)80073-8 |
0.362 |
|
| 1995 |
Shoji S, Ertl RF, Koyama S, Robbins R, Leikauf G, Von Essen S, Rennard SI. Cigarette smoke stimulates release of neutrophil chemotactic activity from cultured bovine bronchial epithelial cells. Clinical Science (London, England : 1979). 88: 337-44. PMID 7736704 DOI: 10.1042/Cs0880337 |
0.343 |
|
| 1995 |
Berkowitz RB, Tinkelman DG, Marcoux JP, Rooklin AR, Zeitz HJ, Rennard SI, Moss BA, Hubbard RC, Lorber RR. Conversion from twice- to once-daily extended-release theophylline treatment in patients with reversible airway obstruction. The Journal of Asthma : Official Journal of the Association For the Care of Asthma. 32: 275-84. PMID 7629003 DOI: 10.3109/02770909509044835 |
0.312 |
|
| 1994 |
Bone R, Boyars M, Braun SR, Buist AS, Campbell S, Chick T, Cohen BM, Conway W, Cugell DW, DeGraff A, Friedman M, George RB, Gershwin E, Kram JA, Levin DC, ... ... Rennard SI, et al. In chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone: An 85-day multicenter trial Chest. 105: 1411-1419. PMID 8181328 DOI: 10.1378/Chest.105.5.1411 |
0.365 |
|
| 1994 |
Sisson JH, Papi A, Beckmann JD, Leise KL, Wisecarver J, Brodersen BW, Kelling CL, Spurzem JR, Rennard SI. Smoke and viral infection cause cilia loss detectable by bronchoalveolar lavage cytology and dynein ELISA. American Journal of Respiratory and Critical Care Medicine. 149: 205-13. PMID 8111584 DOI: 10.1164/Ajrccm.149.1.8111584 |
0.337 |
|
| 1994 |
Rennard SI, Romberger DJ, Sisson JH, Von Essen SG, Rubinstein I, Robbins RA, Spurzem JR. Airway epithelial cells: functional roles in airway disease. American Journal of Respiratory and Critical Care Medicine. 150: S27-30. PMID 7952587 DOI: 10.1164/Ajrccm/150.5_Pt_2.S27 |
0.321 |
|
| 1992 |
Robbins RA, Koyama S, Spurzem JR, Rickard KA, Nelson KJ, Gossman GL, Thiele GM, Rennard SI. Modulation of neutrophil and mononuclear cell adherence to bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 7: 19-29. PMID 1627334 DOI: 10.1165/Ajrcmb/7.1.19 |
0.309 |
|
| 1992 |
Rickard KA, Taylor J, Rennard SI. Observations of development of resistance to detachment of cultured bovine bronchial epithelial cells in response to protease treatment. American Journal of Respiratory Cell and Molecular Biology. 6: 414-20. PMID 1550686 DOI: 10.1165/Ajrcmb/6.4.414 |
0.348 |
|
| 1991 |
Rennard SI, Rickard K, Beckmann JD, Huerta G, Koyama S, Robbins RA, Romberger D, Spurzem J, Thompson AB. Protease injury in airways disease. Annals of the New York Academy of Sciences. 624: 278-85. PMID 2064228 DOI: 10.1111/J.1749-6632.1991.Tb17026.X |
0.345 |
|
| 1991 |
Rickard KA, Shoji S, Spurzem JR, Rennard SI. Attachment characteristics of bovine bronchial epithelial cells to extracellular matrix components. American Journal of Respiratory Cell and Molecular Biology. 4: 440-8. PMID 2021481 DOI: 10.1165/Ajrcmb/4.5.440 |
0.305 |
|
| 1991 |
Metcalf JP, Thompson AB, Gossman GL, Nelson KJ, Koyama S, Rennard SI, Robbins RA. Gcglobulin functions as a cochemotaxin in the lower respiratory tract. A potential mechanism for lung neutrophil recruitment in cigarette smokers. The American Review of Respiratory Disease. 143: 844-9. PMID 2008995 DOI: 10.1164/Ajrccm/143.4_Pt_1.844 |
0.385 |
|
| 1991 |
Vaughan WP, Linder J, Robbins R, Arneson M, Rennard SI. Pulmonary surveillance using bronchoscopy and bronchoalveolar lavage during high-dose antineoplastic therapy. Chest. 99: 105-11. PMID 1984939 DOI: 10.1378/Chest.99.1.105 |
0.354 |
|
| 1991 |
Spurzem JR, Thompson AB, Daughton DM, Mueller M, Linder J, Rennard SI. Chronic inflammation is associated with an increased proportion of goblet cells recovered by bronchial lavage. Chest. 100: 389-93. PMID 1864112 DOI: 10.1378/Chest.100.2.389 |
0.332 |
|
| 1991 |
Sisson JH, Tuma DJ, Rennard SI. Acetaldehyde-mediated cilia dysfunction in bovine bronchial epithelial cells. The American Journal of Physiology. 260: L29-36. PMID 1825452 DOI: 10.1152/Ajplung.1991.260.2.L29 |
0.319 |
|
| 1990 |
Shoji S, Rickard KA, Ertl RF, Robbins RA, Linder J, Rennard SI. Bronchial epithelial cells produce lung fibroblast chemotactic factor: fibronectin. American Journal of Respiratory Cell and Molecular Biology. 1: 13-20. PMID 2624756 DOI: 10.1165/Ajrcmb/1.1.13 |
0.355 |
|
| 1990 |
Fujita J, Nelson NL, Daughton DM, Dobry CA, Spurzem JR, Irino S, Rennard SI. Evaluation of elastase and antielastase balance in patients with chronic bronchitis and pulmonary emphysema. The American Review of Respiratory Disease. 142: 57-62. PMID 2368980 DOI: 10.1164/Ajrccm/142.1.57 |
0.34 |
|
| 1990 |
Takizawa H, Beckmann JD, Shoji S, Claassen LR, Ertl RF, Linder J, Rennard SI. Pulmonary macrophages can stimulate cell growth of bovine bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 2: 245-55. PMID 2310583 DOI: 10.1165/Ajrcmb/2.3.245 |
0.339 |
|
| 1990 |
Shoji S, Rickard KA, Takizawa H, Ertl RF, Linder J, Rennard SI. Lung fibroblasts produce growth stimulatory activity for bronchial epithelial cells. The American Review of Respiratory Disease. 141: 433-9. PMID 2301859 DOI: 10.1164/Ajrccm/141.2.433 |
0.341 |
|
| 1990 |
Robbins RA, Gossman GL, Nelson KJ, Koyama S, Thompson AB, Rennard SI. Inactivation of chemotactic factor inactivator by cigarette smoke. A potential mechanism of modulating neutrophil recruitment to the lung. The American Review of Respiratory Disease. 142: 763-8. PMID 2221580 DOI: 10.1164/Ajrccm/142.4.763 |
0.319 |
|
| 1990 |
Rennard SI, Daughton DM, Robbins RA, Thompson AB, Von Essen S. In vivo and in vitro methods for evaluating airways inflammation: implications for respiratory toxicology. Toxicology. 60: 5-14. PMID 2180133 DOI: 10.1016/0300-483X(90)90158-D |
0.349 |
|
| 1990 |
Driscoll KE, Maurer JK, Lindenschmidt RC, Romberger D, Rennard SI, Crosby L. Respiratory tract responses to dust: relationships between dust burden, lung injury, alveolar macrophage fibronectin release, and the development of pulmonary fibrosis. Toxicology and Applied Pharmacology. 106: 88-101. PMID 2174581 DOI: 10.1016/0041-008X(90)90109-8 |
0.327 |
|
| 1990 |
Rennard SI. Future directions for bronchoalveolar lavage. Lung. 1050-6. PMID 2117106 DOI: 10.1007/Bf02718243 |
0.353 |
|
| 1989 |
Shoji S, Rickard KA, Ertl RF, Linder J, Rennard SI. Lung fibroblasts produce chemotactic factors for bronchial epithelial cells. The American Journal of Physiology. 257: L71-9. PMID 2764118 DOI: 10.1152/Ajplung.1989.257.2.L71 |
0.346 |
|
| 1989 |
Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters. The American Review of Respiratory Disease. 140: 1527-37. PMID 2604284 DOI: 10.1164/Ajrccm/140.6.1527 |
0.372 |
|
| 1987 |
Linder J, Vaughan WP, Armitage JO, Ghafouri A, Hurkman D, Mroczek EC, Miller NG, Rennard SI. Cytopathology of opportunistic infection in bronchoalveolar lavage American Journal of Clinical Pathology. 88: 421-428. PMID 2821792 DOI: 10.1093/Ajcp/88.4.421 |
0.325 |
|
| 1986 |
Daughton DM, Kass I, Fix AJ, Ahrens K, Rennard SI. Smoking intervention: combination therapy using nicotine chewing gum and the American Lung Association's "Freedom from Smoking" manuals. Preventive Medicine. 15: 432-435. PMID 3763565 DOI: 10.1016/0091-7435(86)90010-1 |
0.308 |
|
| 1984 |
Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Keogh BA. Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts). The New England Journal of Medicine. 310: 154-66. PMID 6361560 DOI: 10.1056/Nejm198401193100304 |
0.36 |
|
| 1984 |
DAVIS WB, RENNARD SI, BITTERMAN PB, CRYSTAL RG. Pulmonary Oxygen Toxicity Survey of Anesthesiology. 28: 270???271. DOI: 10.1097/00132586-198408000-00003 |
0.301 |
|
| 1983 |
Davis WB, Rennard SI, Bitterman PB, Crystal RG. Pulmonary oxygen toxicity. Early reversible changes in human alveolar structures induced by hyperoxia. The New England Journal of Medicine. 309: 878-83. PMID 6888481 DOI: 10.1056/Nejm198310133091502 |
0.329 |
|
| 1982 |
Rennard SI, Crystal RG. Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung disease. Journal of Clinical Investigation. 69: 113-122. PMID 7054232 DOI: 10.1172/Jci110421 |
0.386 |
|
| 1982 |
Rennard SI, Hunninghake GW, Bitterman PB, Crystal RG. Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Proceedings of the National Academy of Sciences of the United States of America. 78: 7147-51. PMID 6947279 DOI: 10.1073/Pnas.78.11.7147 |
0.372 |
|
| 1981 |
Crystal RG, Rennard SI. Pulmonary Connective Tissue and Environmental Lung Disease Chest. 80: 33. PMID 7249734 DOI: 10.1378/Chest.80.1_Supplement.33S-A |
0.376 |
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