| Year |
Citation |
Score |
| 2024 |
Somé AF, Conrad MD, Kabré Z, Fofana A, Yerbanga RS, Bazié T, Neya C, Somé M, Kagambega TJ, Legac J, Garg S, Bailey JA, Ouédraogo J-B, Rosenthal PJ, Cooper RA. drug susceptibility and resistance mediating genetic polymorphisms of in Bobo-Dioulasso, Burkina Faso. Antimicrobial Agents and Chemotherapy. e0153423. PMID 38411062 DOI: 10.1128/aac.01534-23 |
0.345 |
|
| 2023 |
Kreutzfeld O, Tumwebaze PK, Okitwi M, Orena S, Byaruhanga O, Katairo T, Conrad MD, Rasmussen SA, Legac J, Aydemir O, Giesbrecht D, Forte B, Campbell P, Smith A, Kano H, ... ... Cooper RA, et al. Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiology Spectrum. e0523622. PMID 37158739 DOI: 10.1128/spectrum.05236-22 |
0.365 |
|
| 2022 |
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, ... ... Cooper RA, et al. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications. 13: 2158. PMID 35444200 DOI: 10.1038/s41467-022-29688-5 |
0.301 |
|
| 2021 |
Cooper RA, Kirkman L. Can repurposing drugs play a role in malaria control? The Journal of Experimental Medicine. 218. PMID 34807244 DOI: 10.1084/jem.20211512 |
0.301 |
|
| 2021 |
Kreutzfeld O, Tumwebaze PK, Byaruhanga O, Katairo T, Okitwi M, Orena S, Rasmussen SA, Legac J, Conrad MD, Nsobya SL, Aydemir O, Bailey JA, Duffey M, Cooper RA, Rosenthal PJ. Decreased susceptibility to dihydrofolate reductase inhibitors associated with genetic polymorphisms in Ugandan Plasmodium falciparum isolates. The Journal of Infectious Diseases. PMID 34460932 DOI: 10.1093/infdis/jiab435 |
0.33 |
|
| 2021 |
Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, ... ... Cooper RA, et al. The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to parasite resistance. Science Translational Medicine. 13. PMID 34290058 DOI: 10.1126/scitranslmed.abg6013 |
0.312 |
|
| 2021 |
Duvalsaint M, Conrad MD, Tukwasibwe S, Tumwebaze PK, Legac J, Cooper RA, Rosenthal PJ. Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum. Malaria Journal. 20: 292. PMID 34193148 DOI: 10.1186/s12936-021-03823-x |
0.328 |
|
| 2020 |
Butler JH, Baptista RP, Valenciano AL, Zhou B, Kissinger JC, Tumwebaze PK, Rosenthal PJ, Cooper R, Yue JM, Cassera MB. Resistance to some, but not other dimeric lindenane sesquiterpenoid esters is mediated by mutations in a Plasmodium falciparum esterase. Acs Infectious Diseases. PMID 32970404 DOI: 10.1021/acsinfecdis.0c00487 |
0.302 |
|
| 2020 |
Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, ... ... Cooper R, et al. Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry. PMID 32390431 DOI: 10.1021/Acs.Jmedchem.0C00539 |
0.398 |
|
| 2020 |
Sindhe KMV, Wu W, Legac J, Zhang YK, Easom EE, Cooper RA, Plattner JJ, Freund YR, DeRisi JL, Rosenthal PJ. Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation. Mbio. 11. PMID 31992618 DOI: 10.1128/Mbio.02640-19 |
0.45 |
|
| 2019 |
Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick GD, Wong TT, Okoro JI, Scales RM, Tumwebaze PT, Rosenthal PJ, Kafsack BFC, ... Cooper R, et al. Improvement of asparagine ethylenediamines as anti-malarial Plasmodium-selective proteasome inhibitors. Journal of Medicinal Chemistry. PMID 31177777 DOI: 10.1021/Acs.Jmedchem.9B00363 |
0.369 |
|
| 2019 |
Dodean RA, Kancharla P, Li Y, Melendez V, Read L, Bane C, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, ... ... Cooper R, et al. Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of Medicinal Chemistry. PMID 30852885 DOI: 10.1021/Acs.Jmedchem.8B01961 |
0.389 |
|
| 2017 |
Rasmussen SA, Ceja FG, Conrad MD, Tumwebaze PK, Byaruhanga O, Katairo T, Nsobya SL, Rosenthal PJ, Cooper RA. Changing antimalarial drug sensitivities in Uganda. Antimicrobial Agents and Chemotherapy. PMID 28923866 DOI: 10.1128/Aac.01516-17 |
0.4 |
|
| 2017 |
Dhingra SK, Redhi D, Combrinck JM, Yeo T, Okombo J, Henrich PP, Cowell AN, Gupta P, Stegman ML, Hoke JM, Cooper RA, Winzeler E, Mok S, Egan TJ, Fidock DA. A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine. Mbio. 8. PMID 28487425 DOI: 10.1128/Mbio.00303-17 |
0.468 |
|
| 2017 |
Sonoiki E, Ng CL, Lee MC, Guo D, Zhang YK, Zhou Y, Alley MR, Ahyong V, Sanz LM, Lafuente-Monasterio MJ, Dong C, Schupp PG, Gut J, Legac J, Cooper RA, et al. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Nature Communications. 8: 14574. PMID 28262680 DOI: 10.1038/Ncomms14574 |
0.393 |
|
| 2016 |
Sonoiki E, Palencia A, Guo D, Ahyong V, Dong C, Li X, Hernandez VS, Zhang YK, Choi W, Gut J, Legac J, Cooper R, Alley MR, Freund YR, DeRisi J, et al. Anti-malarial benzoxaboroles target P. falciparum leucyl-tRNA synthetase. Antimicrobial Agents and Chemotherapy. PMID 27270277 DOI: 10.1128/Aac.00820-16 |
0.466 |
|
| 2015 |
Pulcini S, Staines HM, Lee AH, Shafik SH, Bouyer G, Moore CM, Daley DA, Hoke MJ, Altenhofen LM, Painter HJ, Mu J, Ferguson DJ, Llinás M, Martin RE, Fidock DA, ... Cooper RA, et al. Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities. Scientific Reports. 5: 14552. PMID 26420308 DOI: 10.1038/Srep14552 |
0.435 |
|
| 2015 |
Cooper RA, Conrad MD, Watson QD, Huezo SJ, Ninsiima H, Tumwebaze P, Nsobya SL, Rosenthal PJ. Lack of artemisinin resistance in Plasmodium falciparum in Uganda based on parasitological and molecular assays. Antimicrobial Agents and Chemotherapy. PMID 26033725 DOI: 10.1128/Aac.00921-15 |
0.38 |
|
| 2015 |
Tumwebaze P, Conrad MD, Walakira A, LeClair N, Byaruhanga O, Nakazibwe C, Kozak B, Bloome J, Okiring J, Kakuru A, Bigira V, Kapisi J, Legac J, Gut J, Cooper RA, et al. Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children. Antimicrobial Agents and Chemotherapy. 59: 3018-30. PMID 25753626 DOI: 10.1128/Aac.05141-14 |
0.405 |
|
| 2012 |
Griffin CE, Hoke JM, Samarakoon U, Duan J, Mu J, Ferdig MT, Warhurst DC, Cooper RA. Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids. Antimicrobial Agents and Chemotherapy. 56: 5356-64. PMID 22869567 DOI: 10.1128/Aac.05667-11 |
0.402 |
|
| 2011 |
Hartwig CL, Lauterwasser EM, Mahajan SS, Hoke JM, Cooper RA, Renslo AR. Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes. Journal of Medicinal Chemistry. 54: 8207-13. PMID 22023506 DOI: 10.1021/Jm2012003 |
0.667 |
|
| 2010 |
Patel JJ, Thacker D, Tan JC, Pleeter P, Checkley L, Gonzales JM, Deng B, Roepe PD, Cooper RA, Ferdig MT. Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross. Molecular Microbiology. 78: 770-87. PMID 20807203 DOI: 10.1111/J.1365-2958.2010.07366.X |
0.417 |
|
| 2009 |
Kelly JX, Smilkstein MJ, Brun R, Wittlin S, Cooper RA, Lane KD, Janowsky A, Johnson RA, Dodean RA, Winter R, Hinrichs DJ, Riscoe MK. Discovery of dual function acridones as a new antimalarial chemotype. Nature. 459: 270-3. PMID 19357645 DOI: 10.1038/Nature07937 |
0.447 |
|
| 2009 |
Hartwig CL, Rosenthal AS, D'Angelo J, Griffin CE, Posner GH, Cooper RA. Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent Biochemical Pharmacology. 77: 322-336. PMID 19022224 DOI: 10.1016/J.Bcp.2008.10.015 |
0.671 |
|
| 2008 |
Jiang H, Patel JJ, Yi M, Mu J, Ding J, Stephens R, Cooper RA, Ferdig MT, Su XZ. Genome-wide compensatory changes accompany drug- selected mutations in the Plasmodium falciparum crt gene. Plos One. 3: e2484. PMID 18575593 DOI: 10.1371/Journal.Pone.0002484 |
0.437 |
|
| 2008 |
Gligorijevic B, Purdy K, Elliott DA, Cooper RA, Roepe PD. Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy. Molecular and Biochemical Parasitology. 159: 7-23. PMID 18281110 DOI: 10.1016/J.Molbiopara.2007.12.014 |
0.394 |
|
| 2007 |
Kelly JX, Smilkstein MJ, Cooper RA, Lane KD, Johnson RA, Janowsky A, Dodean RA, Hinrichs DJ, Winter R, Riscoe M. Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 51: 4133-40. PMID 17846138 DOI: 10.1128/Aac.00669-07 |
0.44 |
|
| 2007 |
Montgomery-Fullerton MM, Cooper RA, Kauffman KM, Shields JD, Ratzlaff RE. Detection of Panulirus argus Virus 1 in Caribbean spiny lobsters. Diseases of Aquatic Organisms. 76: 1-6. PMID 17718159 DOI: 10.3354/Dao076001 |
0.335 |
|
| 2007 |
Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, Wellems TE, Su X, Ferdig MT. Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine. Molecular Microbiology. 63: 270-82. PMID 17163969 DOI: 10.1111/J.1365-2958.2006.05511.X |
0.401 |
|
| 2006 |
Li C, Shields JD, Small HJ, Reece KS, Hartwig CL, Cooper RA, Ratzlaff RE. Detection of Panulirus argus Virus 1 (PaVI) in the Caribbean spiny lobster using fluorescence in situ hybridization (FISH). Diseases of Aquatic Organisms. 72: 185-92. PMID 17190197 DOI: 10.3354/Dao072185 |
0.644 |
|
| 2005 |
Cooper RA, Papakrivos J, Lane KD, Fujioka H, Lingelbach K, Wellems TE. PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites. Molecular and Biochemical Parasitology. 144: 167-76. PMID 16183150 DOI: 10.1016/J.Molbiopara.2005.07.009 |
0.313 |
|
| 2005 |
Cooper RA, Hartwig CL, Ferdig MT. pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective. Acta Tropica. 94: 170-80. PMID 15866507 DOI: 10.1016/J.Actatropica.2005.04.004 |
0.658 |
|
| 2004 |
Cooper RA, Carucci DJ. Proteomic approaches to studying drug targets and resistance in Plasmodium. Current Drug Targets. Infectious Disorders. 4: 41-51. PMID 15032633 DOI: 10.2174/1568005043480989 |
0.314 |
|
| 2003 |
Mu J, Ferdig MT, Feng X, Joy DA, Duan J, Furuya T, Subramanian G, Aravind L, Cooper RA, Wootton JC, Xiong M, Su XZ. Multiple transporters associated with malaria parasite responses to chloroquine and quinine. Molecular Microbiology. 49: 977-89. PMID 12890022 DOI: 10.1046/J.1365-2958.2003.03627.X |
0.445 |
|
| 2002 |
Wootton JC, Feng X, Ferdig MT, Cooper RA, Mu J, Baruch DI, Magill AJ, Su XZ. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature. 418: 320-3. PMID 12124623 DOI: 10.1038/Nature00813 |
0.335 |
|
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