Peter Hotez, M.D., Ph.D - Publications

Affiliations: 
Molecular Virology and Microbiology Baylor College of Medicine, Houston, TX 
Area:
Hookworm, Neglected Tropical Diseases
Website:
http://www.bcm.edu/tropicalmedicine/peter-hotez

336 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Biter AB, Pollet J, Chen WH, Strych U, Hotez PJ, Bottazzi ME. A method to probe protein structure from UV absorbance spectra. Analytical Biochemistry. 113450. PMID 31550438 DOI: 10.1016/j.ab.2019.113450  0.32
2019 P JG, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. Plos Neglected Tropical Diseases. 13: e0007730. PMID 31525197 DOI: 10.1371/journal.pntd.0007730  0.32
2019 Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Response to `letter to the editor: 'Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America'´. Expert Review of Anti-Infective Therapy. 1-3. PMID 31361163 DOI: 10.1080/14787210.2019.1649139  0.32
2019 Bottazzi ME, Hotez PJ. "Running the Gauntlet": Formidable challenges in advancing neglected tropical diseases vaccines from development through licensure, and a "Call to Action". Human Vaccines & Immunotherapeutics. PMID 31180271 DOI: 10.1080/21645515.2019.1629254  0.32
2019 Barry MA, Versteeg L, Wang Q, Pollet J, Zhan B, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. Plos Neglected Tropical Diseases. 13: e0007413. PMID 31145733 DOI: 10.1371/journal.pntd.0007413  0.32
2019 Bartsch SM, Bottazzi ME, Asti L, Strych U, Meymandi S, Falcón-Lezama JA, Randall S, Hotez PJ, Lee BY. Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients. Vaccine. PMID 31104883 DOI: 10.1016/j.vaccine.2019.05.028  0.32
2019 Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America. Expert Review of Anti-Infective Therapy. 1-13. PMID 30712412 DOI: 10.1080/14787210.2019.1577731  0.32
2019 Wang L, Zou Y, Zhu X, Bottazzi ME, Hotez PJ, Zhan B. China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative. Plos Neglected Tropical Diseases. 13: e0006946. PMID 30677027 DOI: 10.1371/journal.pntd.0006946  0.32
2018 Gazzinelli-Guimarães AC, Gazzinelli-Guimarães PH, Nogueira DS, Oliveira FMS, Barbosa FS, Amorim CCO, Cardoso MS, Kraemer L, Caliari MV, Akamatsu MA, Ho PL, Jones KM, Weatherhead J, Bottazzi ME, Hotez PJ, et al. IgG Induced by Vaccination With Extracts Is Protective Against Infection. Frontiers in Immunology. 9: 2535. PMID 30473693 DOI: 10.3389/fimmu.2018.02535  0.32
2018 Hotez PJ, Bottazzi ME, Bethony J, Diemert DD. Advancing the Development of a Human Schistosomiasis Vaccine. Trends in Parasitology. PMID 30455112 DOI: 10.1016/j.pt.2018.10.005  0.32
2018 Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. Plos Neglected Tropical Diseases. 12: e0006772. PMID 30296268 DOI: 10.1371/journal.pntd.0006772  0.32
2018 Weatherhead JE, Porter P, Coffey A, Haydel D, Versteeg L, Zhan B, Gazzinelli Guimarães AC, Fujiwara R, Jaramillo AM, Bottazzi ME, Hotez PJ, Corry DB, Beaumier CM. Larval Infection and Lung Invasion Directly Induces Severe Allergic Airway Disease in Mice. Infection and Immunity. PMID 30249744 DOI: 10.1128/IAI.00533-18  0.32
2018 de la Cruz JJ, Villanueva-Lizama L, Dzul-Huchim V, Ramírez-Sierra MJ, Martinez-Vega P, Rosado-Vallado M, Ortega-Lopez J, Flores-Pucheta CI, Gillespie P, Zhan B, Bottazzi ME, Hotez PJ, Dumonteil E. Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Human Vaccines & Immunotherapeutics. PMID 30192702 DOI: 10.1080/21645515.2018.1520581  0.32
2018 Briggs N, Wei J, Versteeg L, Zhan B, Keegan B, Damania A, Pollet J, Hayes KS, Beaumier C, Seid CA, Leong J, Grencis RK, Bottazzi ME, Sastry KJ, Hotez PJ. Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. Plos Pathogens. 14: e1007273. PMID 30153307 DOI: 10.1371/journal.ppat.1007273  0.32
2018 Gunter SM, Versteeg L, Jones KM, Brian KP, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production. Parasite Immunology. e12585. PMID 30132929 DOI: 10.1111/pim.12585  0.32
2018 Diemert DJ, Bottazzi ME, Plieskatt J, Hotez PJ, Bethony JM. Lessons along the Critical Path: Developing Vaccines against Human Helminths. Trends in Parasitology. PMID 30064902 DOI: 10.1016/j.pt.2018.07.005  0.32
2018 Bouchery T, Filbey K, Shepherd A, Chandler J, Patel D, Schmidt A, Camberis M, Peignier A, Smith AAT, Johnston K, Painter G, Pearson M, Giacomin P, Loukas A, Bottazzi ME, ... Hotez P, et al. A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. Plos Pathogens. 14: e1006931. PMID 29566094 DOI: 10.1371/journal.ppat.1006931  0.32
2018 Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ. Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen. Vaccine. PMID 29496347 DOI: 10.1016/j.vaccine.2018.02.065  0.32
2018 Villanueva-Lizama LE, Cruz-Chan JV, Aguilar-Cetina ADC, Herrera-Sanchez LF, Rodriguez-Perez JM, Rosado-Vallado ME, Ramirez-Sierra MJ, Ortega-Lopez J, Jones K, Hotez P, Bottazzi ME, Dumonteil E. Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. Plos Neglected Tropical Diseases. 12: e0006240. PMID 29377898 DOI: 10.1371/journal.pntd.0006240  0.32
2018 Jones K, Versteeg L, Damania A, Keegan B, Kendricks A, Pollet J, Cruz-Chan JV, Gusovsky F, Hotez PJ, Bottazzi ME. Vaccine-linked chemotherapy improves benznidazole efficacy for acute Chagas disease. Infection and Immunity. PMID 29311242 DOI: 10.1128/IAI.00876-17  0.32
2017 Biter AB, Weltje S, Hudspeth EM, Seid CA, McAtee CP, Chen WH, Pollet JB, Strych U, Hotez PJ, Bottazzi ME. Characterization and stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a candidate antigen for a therapeutic vaccine against Chagas disease. Journal of Pharmaceutical Sciences. PMID 29274820 DOI: 10.1016/j.xphs.2017.12.014  0.32
2017 McKenna ML, McAtee S, Bryan PE, Jeun R, Ward T, Kraus J, Bottazzi ME, Hotez PJ, Flowers CC, Mejia R. Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. The American Journal of Tropical Medicine and Hygiene. PMID 29016326 DOI: 10.4269/ajtmh.17-0396  0.32
2017 Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Onchocerca volvulus: The Road from Basic Biology to a Vaccine. Trends in Parasitology. PMID 28958602 DOI: 10.1016/j.pt.2017.08.011  0.32
2017 Liu Z, Kelleher A, Tabb S, Wei J, Pollet J, Hotez PJ, Bottazzi ME, Zhan B, Asojo OA. Identification, Characterization, and Structure of Tm16 from Trichuris muris. Journal of Parasitology Research. 2017: 4342789. PMID 28884022 DOI: 10.1155/2017/4342789  0.32
2017 Wei J, Versteeg L, Liu Z, Keegan B, Gazzinelli-Guimarães AC, Fujiwara RT, Briggs N, Jones KM, Strych U, Beaumier CM, Bottazzi ME, Hotez PJ, Zhan B. Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. Plos Neglected Tropical Diseases. 11: e0005769. PMID 28708895 DOI: 10.1371/journal.pntd.0005769  0.32
2017 Konduri V, Halpert MM, Liang D, Levitt JM, Cruz JVC, Zhan B, Bottazzi ME, Hotez PJ, Jones KM, Decker WK. Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy. Infection and Immunity. PMID 28674032 DOI: 10.1128/IAI.00127-17  0.32
2017 Brown EL, Gunter S, Jones KM, Seid C, Essigmann HT, Bottazzi ME, Hotez PJ, Zhan B, Strych U. Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis. The Journal of Parasitology. PMID 28581897 DOI: 10.1645/17-7  0.32
2017 Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, ... ... Hotez P, et al. Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. Plos Neglected Tropical Diseases. 11: e0005574. PMID 28464026 DOI: 10.1371/journal.pntd.0005574  0.32
2017 Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ. Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate. Journal of Pharmaceutical Sciences. PMID 28456726 DOI: 10.1016/j.xphs.2017.04.037  0.32
2017 Asojo OA, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, Abdeladhim M, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, ... Hotez PJ, et al. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. Plos Neglected Tropical Diseases. 11: e0005374. PMID 28278244 DOI: 10.1371/journal.pntd.0005374  0.32
2017 Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine. Plos Neglected Tropical Diseases. 11: e0005385. PMID 28192438 DOI: 10.1371/journal.pntd.0005385  0.32
2017 Pollet J, Versteeg L, Rezende W, Strych U, Gusovsky F, Hotez PJ, Bottazzi ME. A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations. Vaccine. PMID 28190745 DOI: 10.1016/j.vaccine.2017.01.077  0.32
2016 Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Hookworm infection. Nature Reviews. Disease Primers. 2: 16088. PMID 27929101 DOI: 10.1038/nrdp.2016.88  0.32
2016 Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, et al. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine. 8: 362ra143. PMID 27797959 DOI: 10.1126/scitranslmed.aaf8807  0.32
2016 McAtee CP, Seid CA, Hammond M, Hudspeth E, Keegan BP, Liu Z, Wei J, Zhan B, Arjona-Sabido R, Cruz-Chan V, Dumonteil E, Hotez PJ, Bottazzi ME. Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis. Protein Expression and Purification. PMID 27773761 DOI: 10.1016/j.pep.2016.10.008  0.32
2016 Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, ... Hotez PJ, et al. Cysteine Mutagenesis Improves the Production without Abrogating Antigenicity of a Recombinant Protein Vaccine Candidate for Human Chagas Disease. Human Vaccines & Immunotherapeutics. 0. PMID 27737611 DOI: 10.1080/21645515.2016.1242540  0.32
2016 Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B. The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates. Parasites & Vectors. 9: 518. PMID 27677574 DOI: 10.1186/s13071-016-1795-8  0.68
2016 Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY. The Global Economic and Health Burden of Human Hookworm Infection. Plos Neglected Tropical Diseases. 10: e0004922. PMID 27607360 DOI: 10.1371/journal.pntd.0004922  0.32
2016 Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. Plos Neglected Tropical Diseases. 10: e0004797. PMID 27387453 DOI: 10.1371/journal.pntd.0004797  0.68
2016 Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. PMID 27171753 DOI: 10.1016/j.vaccine.2016.03.112  0.68
2016 Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. Plos Neglected Tropical Diseases. 10: e0004586. PMID 27045170 DOI: 10.1371/journal.pntd.0004586  0.68
2016 Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. PMID 27040400 DOI: 10.1016/j.vaccine.2016.03.078  0.32
2016 Merrifield M, Hotez PJ, Beaumier CM, Gillespie P, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent human schistosomiasis. Vaccine. PMID 27036511 DOI: 10.1016/j.vaccine.2016.03.079  0.32
2016 Beaumier CM, Gillespie PM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. PMID 27026146 DOI: 10.1016/j.vaccine.2016.03.074  0.32
2016 Bartsch SM, Hotez PJ, Hertenstein DL, Diemert DJ, Zapf KM, Bottazzi ME, Bethony JM, Brown ST, Lee BY. Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting. Vaccine. PMID 27002501 DOI: 10.1016/j.vaccine.2016.03.018  0.68
2016 Gillespie PM, Beaumier CM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for leishmaniasis. Vaccine. PMID 26973063 DOI: 10.1016/j.vaccine.2015.12.071  0.32
2016 Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, Tapia-Conyer R, Reeder JC. Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. Plos Neglected Tropical Diseases. 10: e0003895. PMID 26934395 DOI: 10.1371/journal.pntd.0003895  0.68
2016 Barry MA, Murray KO, Hotez PJ, Jones KM. Impact of vectorborne parasitic neglected tropical diseases on child health. Archives of Disease in Childhood. PMID 26921274 DOI: 10.1136/archdischild-2015-308266  0.68
2016 Pecoul B, Batista C, Stobbaerts E, Ribeiro I, Vilasanjuan R, Gascon J, Pinazo MJ, Moriana S, Gold S, Pereiro A, Navarro M, Torrico F, Bottazzi ME, Hotez PJ. The BENEFIT Trial: Where Do We Go from Here? Plos Neglected Tropical Diseases. 10: e0004343. PMID 26913759 DOI: 10.1371/journal.pntd.0004343  0.68
2016 Barry MA, Wang Q, Jones KM, Heffernan MJ, Buhaya MH, Beaumier CM, Keegan BP, Zhan B, Dumonteil E, Bottazzi ME, Hotez PJ. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Human Vaccines & Immunotherapeutics. 0. PMID 26890466 DOI: 10.1080/21645515.2015.1119346  0.68
2016 Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, et al. Expression and Purification of an Engineered, Yeast-expressed Leishmania donovani Nucleoside Hydrolase with Immunogenic Properties. Human Vaccines & Immunotherapeutics. 0. PMID 26839079 DOI: 10.1080/21645515.2016.1139254  0.68
2015 Garcia MN, Hernandez D, Gorchakov R, Murray KO, Hotez PJ. The 1899 United States Kissing Bug Epidemic. Plos Neglected Tropical Diseases. 9: e0004117. PMID 26719888 DOI: 10.1371/journal.pntd.0004117  0.68
2015 Hotez PJ, Herricks JR. Impact of the Neglected Tropical Diseases on Human Development in the Organisation of Islamic Cooperation Nations. Plos Neglected Tropical Diseases. 9: e0003782. PMID 26606509 DOI: 10.1371/journal.pntd.0003782  0.68
2015 Gunter SM, Jones KM, Zhan B, Essigmann HT, Murray KO, Garcia MN, Gorchakov R, Bottazzi ME, Hotez PJ, Brown EL. Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24. The American Journal of Tropical Medicine and Hygiene. PMID 26598565 DOI: 10.4269/ajtmh.15-0438  0.68
2015 Garcia MN, Woc-Colburn L, Aguilar D, Hotez PJ, Murray KO. Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States. Plos Neglected Tropical Diseases. 9: e0003981. PMID 26540273 DOI: 10.1371/journal.pntd.0003981  0.68
2015 Anderson JP, Rascoe LN, Levert K, Chastain HM, Reed MS, Rivera HN, McAuliffe I, Zhan B, Wiegand RE, Hotez PJ, Wilkins PP, Pohl J, Handali S. Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26. Plos Neglected Tropical Diseases. 9: e0004168. PMID 26485145 DOI: 10.1371/journal.pntd.0004168  0.68
2015 Zhan B, Ajmera R, Geiger S, Gonçalves MT, Liu Z, Wei J, Wilkins PP, Fujiwara R, Gazzinelli-Guimaraes PH, Bottazzi ME, Hotez P. Identification of Immunodominant Antigens for the Laboratory Diagnosis of Toxocariasis. Tropical Medicine & International Health : Tm & Ih. PMID 26426162 DOI: 10.1111/tmi.12607  0.68
2015 Hotez PJ. Vaccine Science Diplomacy: Expanding Capacity to Prevent Emerging and Neglected Tropical Diseases Arising from Islamic State (IS)--Held Territories. Plos Neglected Tropical Diseases. 9: e0003852. PMID 26402466 DOI: 10.1371/journal.pntd.0003852  0.68
2015 Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annual Review of Medicine. PMID 26356803 DOI: 10.1146/annurev-med-051214-024241  0.68
2015 Murray KO, Fischer RS, Chavarria D, Duttmann C, Garcia MN, Gorchakov R, Hotez PJ, Jiron W, Leibler JH, Lopez JE, Mandayam S, Marin A, Sheleby J. Mesoamerican nephropathy: A neglected tropical disease with an infectious etiology? Microbes and Infection / Institut Pasteur. PMID 26320026 DOI: 10.1016/j.micinf.2015.08.005  0.68
2015 Hotez PJ. Correction: Blue Marble Health Redux: Neglected Tropical Diseases and Human Development in the Group of 20 (G20) Nations and Nigeria. Plos Neglected Tropical Diseases. 9: e0004035. PMID 26288381 DOI: 10.1371/journal.pntd.0004035  0.68
2015 Weatherhead JE, Hotez PJ. Worm Infections in Children. Pediatrics in Review / American Academy of Pediatrics. 36: 341-52; quiz 353-4. PMID 26232464 DOI: 10.1542/pir.36-8-341  0.68
2015 Hotez PJ. Blue Marble Health Redux: Neglected Tropical Diseases and Human Development in the Group of 20 (G20) Nations and Nigeria. Plos Neglected Tropical Diseases. 9: e0003672. PMID 26218831 DOI: 10.1371/journal.pntd.0003672  0.68
2015 Hotez PJ, Peiperl L. Noncommunicable Diseases: A Globalization of Disparity? Plos Medicine. 12: e1001859. PMID 26218734 DOI: 10.1371/journal.pmed.1001859  0.68
2015 Martinez-Campos V, Martinez-Vega P, Ramirez-Sierra MJ, Rosado-Vallado M, Seid CA, Hudspeth EM, Wei J, Liu Z, Kwityn C, Hammond M, Ortega-López J, Zhan B, Hotez PJ, Bottazzi ME, Dumonteil E. Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice. Vaccine. PMID 26192358 DOI: 10.1016/j.vaccine.2015.07.017  0.68
2015 Hotez PJ. Neglected Tropical Diseases in the Ebola-Affected Countries of West Africa. Plos Neglected Tropical Diseases. 9: e0003671. PMID 26110778 DOI: 10.1371/journal.pntd.0003671  0.68
2015 Pearson MS, Jariwala AR, Abbenante G, Plieskatt J, Wilson D, Bottazzi ME, Hotez PJ, Keegan B, Bethony JM, Loukas A. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics. 11: 1251-7. PMID 26018444 DOI: 10.4161/21645515.2014.980199  0.68
2015 Hotez PJ. Blue marble health and "the big three diseases": HIV/AIDS, tuberculosis, and malaria. Microbes and Infection / Institut Pasteur. 17: 539-41. PMID 26003523 DOI: 10.1016/j.micinf.2015.05.004  0.68
2015 Hotez PJ, Herricks JR. Helminth elimination in the pursuit of sustainable development goals: a "worm index" for human development. Plos Neglected Tropical Diseases. 9: e0003618. PMID 25928617 DOI: 10.1371/journal.pntd.0003618  0.68
2015 Seid CA, Curti E, Jones RM, Hudspeth E, Rezende W, Pollet J, Center L, Versteeg L, Pritchard S, Musiychuk K, Yusibov V, Hotez PJ, Bottazzi ME. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Human Vaccines & Immunotherapeutics. 11: 1474-88. PMID 25905574 DOI: 10.1080/21645515.2015.1036207  0.68
2015 Hotez PJ. Combating the next lethal epidemic. Science (New York, N.Y.). 348: 296-7. PMID 25883348 DOI: 10.1126/science.348.6232.296-b  0.68
2015 Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. Plos Neglected Tropical Diseases. 9: e0003575. PMID 25880767 DOI: 10.1371/journal.pntd.0003575  0.68
2015 Li MG, Hotez PJ, Vrabec JT, Donovan DT. Is chronic suppurative otitis media a neglected tropical disease? Plos Neglected Tropical Diseases. 9: e0003485. PMID 25811602 DOI: 10.1371/journal.pntd.0003485  0.68
2015 Hotez PJ, Bottazzi ME, Dumonteil E, Buekens P. The Gulf of Mexico: a "hot zone" for neglected tropical diseases? Plos Neglected Tropical Diseases. 9: e0003481. PMID 25719411 DOI: 10.1371/journal.pntd.0003481  0.68
2015 Preidis GA, Hotez PJ. The newest "omics"--metagenomics and metabolomics--enter the battle against the neglected tropical diseases. Plos Neglected Tropical Diseases. 9: e0003382. PMID 25675250 DOI: 10.1371/journal.pntd.0003382  0.68
2015 Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. The Onchocerciasis Vaccine for Africa--TOVA--Initiative. Plos Neglected Tropical Diseases. 9: e0003422. PMID 25634641 DOI: 10.1371/journal.pntd.0003422  0.68
2015 Jiang S, Hotez PJ. Combating the emerging viral infectious diseases. Microbes and Infection / Institut Pasteur. 17: 83. PMID 25529754 DOI: 10.1016/j.micinf.2014.12.005  0.68
2015 Garcia MN, Murray KO, Hotez PJ, Rossmann SN, Gorchakov R, Ontiveros A, Woc-Colburn L, Bottazzi ME, Rhodes CE, Ballantyne CM, Aguilar D. Development of chagas cardiac manifestations among Texas blood donors. The American Journal of Cardiology. 115: 113-7. PMID 25456877 DOI: 10.1016/j.amjcard.2014.09.050  0.68
2015 Turkeltaub JA, McCarty TR, Hotez PJ. The intestinal protozoa: emerging impact on global health and development. Current Opinion in Gastroenterology. 31: 38-44. PMID 25394233 DOI: 10.1097/MOG.0000000000000135  0.68
2015 Garcia MN, Aguilar D, Gorchakov R, Rossmann SN, Montgomery SP, Rivera H, Woc-Colburn L, Hotez PJ, Murray KO. Evidence of autochthonous Chagas disease in southeastern Texas. The American Journal of Tropical Medicine and Hygiene. 92: 325-30. PMID 25371187 DOI: 10.4269/ajtmh.14-0238  0.68
2014 Hotez PJ. The medical biochemistry of poverty and neglect. Molecular Medicine (Cambridge, Mass.). 20: S31-6. PMID 25549231 DOI: 10.2119/molmed.2014.00169  0.68
2014 Baring E, Hotez PJ. Yemen: fighting neglected tropical diseases against all odds. Plos Neglected Tropical Diseases. 8: e3292. PMID 25521710 DOI: 10.1371/journal.pntd.0003292  0.68
2014 Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Human Vaccines & Immunotherapeutics. 10: 1914-25. PMID 25424799 DOI: 10.4161/hv.28872  0.68
2014 Hotez PJ. Global christianity and the control of its neglected tropical diseases. Plos Neglected Tropical Diseases. 8: e3135. PMID 25412254 DOI: 10.1371/journal.pntd.0003135  0.68
2014 Ndeffo Mbah ML, Skrip L, Greenhalgh S, Hotez P, Galvani AP. Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa. Plos Neglected Tropical Diseases. 8: e3234. PMID 25329403 DOI: 10.1371/journal.pntd.0003234  0.68
2014 Hotez PJ. The NTDs and vaccine diplomacy in latin America: opportunities for united states foreign policy. Plos Neglected Tropical Diseases. 8: e2922. PMID 25255437 DOI: 10.1371/journal.pntd.0002922  0.68
2014 Hotez PJ. Neglected parasitic infections and poverty in the United States. Plos Neglected Tropical Diseases. 8: e3012. PMID 25188455 DOI: 10.1371/journal.pntd.0003012  0.68
2014 Garcia MN, Woc-Colburn L, Rossmann SN, Townsend RL, Stramer SL, Bravo M, Kamel H, Beddard R, Townsend M, Oldham R, Bottazzi ME, Hotez PJ, Murray KO. Trypanosoma cruzi screening in Texas blood donors, 2008-2012. Epidemiology and Infection. 1-4. PMID 25170765 DOI: 10.1017/S0950268814002234  0.68
2014 Lee RM, Moore LB, Bottazzi ME, Hotez PJ. Toxocariasis in North America: a systematic review. Plos Neglected Tropical Diseases. 8: e3116. PMID 25166906 DOI: 10.1371/journal.pntd.0003116  0.68
2014 Hotez PJ. Neglected infections of poverty in the United States and their effects on the brain. Jama Psychiatry. 71: 1099-100. PMID 25103827 DOI: 10.1001/jamapsychiatry.2014.1045  0.68
2014 Rajagopal S, Hotez PJ, Bundy DA. Micronutrient supplementation and deworming in children with geohelminth infections. Plos Neglected Tropical Diseases. 8: e2920. PMID 25101963 DOI: 10.1371/journal.pntd.0002920  0.68
2014 Hotez PJ, Fujiwara RT. Brazil's neglected tropical diseases: an overview and a report card. Microbes and Infection / Institut Pasteur. 16: 601-6. PMID 25088506 DOI: 10.1016/j.micinf.2014.07.006  0.68
2014 Hotez PJ, Peiperl L. Blue marble health: a call for papers. Plos Medicine. 11: e1001682. PMID 25072140 DOI: 10.1371/journal.pmed.1001682  0.68
2014 Hotez PJ, Alvarado M, Basáñez MG, Bolliger I, Bourne R, Boussinesq M, Brooker SJ, Brown AS, Buckle G, Budke CM, Carabin H, Coffeng LE, Fèvre EM, Fürst T, Halasa YA, et al. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. Plos Neglected Tropical Diseases. 8: e2865. PMID 25058013 DOI: 10.1371/journal.pntd.0002865  0.68
2014 Knight JM, Zingales B, Bottazzi ME, Hotez P, Zhan B. Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunology. 36: 708-12. PMID 25040249 DOI: 10.1111/pim.12130  0.68
2014 Garcia MN, Hotez PJ, Murray KO. Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasites & Vectors. 7: 311. PMID 24996479 DOI: 10.1186/1756-3305-7-311  0.68
2014 Hotez PJ. "Vaccine diplomacy": historical perspectives and future directions. Plos Neglected Tropical Diseases. 8: e2808. PMID 24968231 DOI: 10.1371/journal.pntd.0002808  0.68
2014 Hotez PJ, Bottazzi ME, Tseng CT, Zhan B, Lustigman S, Du L, Jiang S. Calling for rapid development of a safe and effective MERS vaccine. Microbes and Infection / Institut Pasteur. 16: 529-31. PMID 24931059 DOI: 10.1016/j.micinf.2014.05.002  0.68
2014 Hess JA, Zhan B, Bonne-Année S, Deckman JM, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. International Journal For Parasitology. 44: 637-46. PMID 24907553 DOI: 10.1016/j.ijpara.2014.04.006  0.68
2014 Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, et al. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3952-64. PMID 24891519 DOI: 10.1096/fj.14-251967  0.68
2014 Hotez PJ. Ten global "hotspots" for the neglected tropical diseases. Plos Neglected Tropical Diseases. 8: e2496. PMID 24873825 DOI: 10.1371/journal.pntd.0002496  0.68
2014 Whitham M, Hotez P. In reply. Obstetrics and Gynecology. 123: 1354. PMID 24848902 DOI: 10.1097/AOG.0000000000000305  0.68
2014 Hotez PJ, Woc-Colburn L, Bottazzi ME. Neglected tropical diseases in Central America and Panama: review of their prevalence, populations at risk and impact on regional development. International Journal For Parasitology. 44: 597-603. PMID 24846528 DOI: 10.1016/j.ijpara.2014.04.001  0.68
2014 Hotez PJ, Murray KO, Buekens P. The Gulf Coast: a new American underbelly of tropical diseases and poverty. Plos Neglected Tropical Diseases. 8: e2760. PMID 24830815 DOI: 10.1371/journal.pntd.0002760  0.68
2014 Webster JP, Molyneux DH, Hotez PJ, Fenwick A. The contribution of mass drug administration to global health: past, present and future. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130434. PMID 24821920 DOI: 10.1098/rstb.2013.0434  0.68
2014 Parise ME, Hotez PJ, Slutsker L. Neglected parasitic infections in the United States: needs and opportunities. The American Journal of Tropical Medicine and Hygiene. 90: 783-5. PMID 24808243 DOI: 10.4269/ajtmh.13-0727  0.68
2014 Güngör K, Hotez PJ, Özdemir V, AynacıoÄŸlu Åž. Glaucomics: a call for systems diagnostics for 21(st) century ophthalmology and personalized visual health. Omics : a Journal of Integrative Biology. 18: 275-9. PMID 24730382 DOI: 10.1089/omi.2014.0040  0.68
2014 Hotez PJ. Could nitazoxanide be added to other essential medicines for integrated neglected tropical disease control and elimination? Plos Neglected Tropical Diseases. 8: e2758. PMID 24675990 DOI: 10.1371/journal.pntd.0002758  0.68
2014 Hotez PJ, Velasquez RM, Wolf JE. Neglected tropical skin diseases: their global elimination through integrated mass drug administration? Jama Dermatology. 150: 481-2. PMID 24671756 DOI: 10.1001/jamadermatol.2013.8759  0.68
2014 Tan M, Kusriastuti R, Savioli L, Hotez PJ. Indonesia: an emerging market economy beset by neglected tropical diseases (NTDs). Plos Neglected Tropical Diseases. 8: e2449. PMID 24587452 DOI: 10.1371/journal.pntd.0002449  0.68
2014 Hotez PJ. Aboriginal populations and their neglected tropical diseases. Plos Neglected Tropical Diseases. 8: e2286. PMID 24498442 DOI: 10.1371/journal.pntd.0002286  0.68
2014 Hotez P, Whitham M. Helminth infections: a new global women's health agenda. Obstetrics and Gynecology. 123: 155-60. PMID 24463676 DOI: 10.1097/AOG.0000000000000025  0.68
2014 Özdemir V, Kolker E, Hotez PJ, Mohin S, Prainsack B, Wynne B, Vayena E, CoÅŸkun Y, Dereli T, Huzair F, Borda-Rodriguez A, Bragazzi NL, Faris J, Ramesar R, Wonkam A, et al. Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy. Omics : a Journal of Integrative Biology. 18: 1-9. PMID 24456464 DOI: 10.1089/omi.2013.0170  0.68
2014 Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, et al. Genome of the human hookworm Necator americanus. Nature Genetics. 46: 261-269. PMID 24441737 DOI: 10.1038/ng.2875  0.6
2014 Zhan B, Beaumier CM, Briggs N, Jones KM, Keegan BP, Bottazzi ME, Hotez PJ. Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Review of Vaccines. 13: 321-31. PMID 24392641 DOI: 10.1586/14760584.2014.872035  0.68
2014 Preidis GA, Keaton MA, Campeau PM, Bessard BC, Conner ME, Hotez PJ. The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress. The Journal of Nutrition. 144: 273-81. PMID 24381221 DOI: 10.3945/jn.113.183731  0.68
2014 Chen WH, Du L, Chag SM, Ma C, Tricoche N, Tao X, Seid CA, Hudspeth EM, Lustigman S, Tseng CT, Bottazzi ME, Hotez PJ, Zhan B, Jiang S. Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate. Human Vaccines & Immunotherapeutics. 10: 648-58. PMID 24355931 DOI: 10.4161/hv.27464  0.68
2014 McCarty TR, Turkeltaub JA, Hotez PJ. Global progress towards eliminating gastrointestinal helminth infections. Current Opinion in Gastroenterology. 30: 18-24. PMID 24241244 DOI: 10.1097/MOG.0000000000000025  0.68
2014 Hotez P. Foreword Clinical Cases in Tropical Medicine. x-xi. DOI: 10.1016/B978-0-7020-5824-0.00083-X  0.68
2013 Beaumier CM, Gomez-Rubio AM, Hotez PJ, Weina PJ. United States military tropical medicine: extraordinary legacy, uncertain future. Plos Neglected Tropical Diseases. 7: e2448. PMID 24386494 DOI: 10.1371/journal.pntd.0002448  0.68
2013 Keenan JD, Hotez PJ, Amza A, Stoller NE, Gaynor BD, Porco TC, Lietman TM. Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. Plos Neglected Tropical Diseases. 7: e2562. PMID 24340111 DOI: 10.1371/journal.pntd.0002562  0.68
2013 Hotez PJ. NTDs V.2.0: "blue marble health"--neglected tropical disease control and elimination in a shifting health policy landscape. Plos Neglected Tropical Diseases. 7: e2570. PMID 24278496 DOI: 10.1371/journal.pntd.0002570  0.68
2013 Hotez PJ, Dumonteil E, Betancourt Cravioto M, Bottazzi ME, Tapia-Conyer R, Meymandi S, Karunakara U, Ribeiro I, Cohen RM, Pecoul B. An unfolding tragedy of Chagas disease in North America. Plos Neglected Tropical Diseases. 7: e2300. PMID 24205411 DOI: 10.1371/journal.pntd.0002300  0.68
2013 Hotez P, Singh SK, Zhou XN. Advancing Sino-Indian cooperation to combat tropical diseases. Plos Neglected Tropical Diseases. 7: e2204. PMID 24086775 DOI: 10.1371/journal.pntd.0002204  0.68
2013 Rimoin AW, Hotez PJ. NTDs in the heart of darkness: the Democratic Republic of Congo's unknown burden of neglected tropical diseases. Plos Neglected Tropical Diseases. 7: e2118. PMID 23936557 DOI: 10.1371/journal.pntd.0002118  0.68
2013 Curti E, Kwityn C, Zhan B, Gillespie P, Brelsford J, Deumic V, Plieskatt J, Rezende WC, Tsao E, Kalampanayil B, Hotez PJ, Bottazzi ME. Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Human Vaccines & Immunotherapeutics. 9: 2342-50. PMID 23899507 DOI: 10.4161/hv.25787  0.68
2013 Cheng W, Curti E, Rezende WC, Kwityn C, Zhan B, Gillespie P, Plieskatt J, Joshi SB, Volkin DB, Hotez PJ, Middaugh CR, Bottazzi ME. Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Human Vaccines & Immunotherapeutics. 9: 2351-61. PMID 23880663 DOI: 10.4161/hv.25788  0.68
2013 Andrus J, Bottazzi ME, Chow J, Goraleski KA, Fisher-Hoch SP, Lambuth JK, Lee BY, Margolis HS, McCormick JB, Melby P, Murray KO, Rico-Hesse R, Valenzuela JG, Hotez PJ. Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas. Plos Neglected Tropical Diseases. 7: e2021. PMID 23826397 DOI: 10.1371/journal.pntd.0002021  0.68
2013 Barry MA, Simon GG, Mistry N, Hotez PJ. Global trends in neglected tropical disease control and elimination: impact on child health. Archives of Disease in Childhood. 98: 635-41. PMID 23793132 DOI: 10.1136/archdischild-2012-302338  0.68
2013 Hotez PJ, Dumonteil E, Heffernan MJ, Bottazzi ME. Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas. Advances in Experimental Medicine and Biology. 764: 1-12. PMID 23654053 DOI: 10.1007/978-1-4614-4726-9-1  0.68
2013 Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, et al. The Human Hookworm Vaccine. Vaccine. 31: B227-32. PMID 23598487 DOI: 10.1016/j.vaccine.2012.11.034  0.68
2013 Beaumier CM, Gillespie PM, Hotez PJ, Bottazzi ME. New vaccines for neglected parasitic diseases and dengue. Translational Research : the Journal of Laboratory and Clinical Medicine. 162: 144-55. PMID 23578479 DOI: 10.1016/j.trsl.2013.03.006  0.68
2013 Özdemir V, Badr KF, Dove ES, Endrenyi L, Geraci CJ, Hotez PJ, Milius D, Neves-Pereira M, Pang T, Rotimi CN, Sabra R, Sarkissian CN, Srivastava S, Tims H, Zgheib NK, et al. Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy. Omics : a Journal of Integrative Biology. 17: 161-72. PMID 23574338 DOI: 10.1089/omi.2013.0034  0.68
2013 Brindley PJ, Hotez PJ. Break Out: urogenital schistosomiasis and Schistosoma haematobium infection in the post-genomic era. Plos Neglected Tropical Diseases. 7: e1961. PMID 23556007 DOI: 10.1371/journal.pntd.0001961  0.68
2013 Barry MA, Weatherhead JE, Hotez PJ, Woc-Colburn L. Childhood parasitic infections endemic to the United States. Pediatric Clinics of North America. 60: 471-85. PMID 23481112 DOI: 10.1016/j.pcl.2012.12.011  0.68
2013 Hotez PJ, Papageorgiou TD. A new European neglected diseases center for Greece? Plos Neglected Tropical Diseases. 7: e1757. PMID 23469292 DOI: 10.1371/journal.pntd.0001757  0.68
2013 Lee BY, Bacon KM, Bottazzi ME, Hotez PJ. Global economic burden of Chagas disease: a computational simulation model. The Lancet. Infectious Diseases. 13: 342-8. PMID 23395248 DOI: 10.1016/S1473-3099(13)70002-1  0.68
2013 Kline K, McCarthy JS, Pearson M, Loukas A, Hotez PJ. Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. Plos Neglected Tropical Diseases. 7: e1755. PMID 23383349 DOI: 10.1371/journal.pntd.0001755  0.68
2013 Sanghvi MM, Hotez PJ, Fenwick A. Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 165-8. PMID 23295048 DOI: 10.1111/liv.12052  0.68
2013 Bacon KM, Hotez PJ, Kruchten SD, Kamhawi S, Bottazzi ME, Valenzuela JG, Lee BY. The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas. Vaccine. 31: 480-6. PMID 23176979 DOI: 10.1016/j.vaccine.2012.11.032  0.68
2013 Farrar J, Hotez PJ, Junghanss T, Kang G, Lalloo D, White NJ. Preface to the Twenty-Third Edition Manson's Tropical Diseases: Twenty-Third Edition. xi-xi. DOI: 10.1016/B978-0-7020-5101-2.00094-7  0.68
2013 Farrar J, Hotez PJ, Junghanss T, Kang G, Lalloo D, White NJ. Manson's Tropical Diseases: Twenty-Third Edition Manson's Tropical Diseases: Twenty-Third Edition. 1-1337.  0.68
2012 Jiang S, Bottazzi ME, Du L, Lustigman S, Tseng CT, Curti E, Jones K, Zhan B, Hotez PJ. Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome. Expert Review of Vaccines. 11: 1405-13. PMID 23252385 DOI: 10.1586/erv.12.126  0.68
2012 Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, ... ... Hotez PJ, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (London, England). 380: 2095-128. PMID 23245604 DOI: 10.1016/S0140-6736(12)61728-0  0.68
2012 Hotez PJ. Engaging a rising China through neglected tropical diseases. Plos Neglected Tropical Diseases. 6: e1599. PMID 23209845 DOI: 10.1371/journal.pntd.0001599  0.68
2012 Dumonteil E, Bottazzi ME, Zhan B, Heffernan MJ, Jones K, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Lee BY, Bacon KM, Fleischer B, Slingsby BT, Cravioto MB, Tapia-Conyer R, ... Hotez PJ, et al. Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Review of Vaccines. 11: 1043-55. PMID 23151163 DOI: 10.1586/erv.12.85  0.68
2012 Hotez PJ, Aksoy S. Now we are six. Plos Neglected Tropical Diseases. 6: e1862. PMID 23145194 DOI: 10.1371/journal.pntd.0001862  0.68
2012 Hotez PJ. Fighting neglected tropical diseases in the southern United States. Bmj (Clinical Research Ed.). 345: e6112. PMID 22977143 DOI: 10.1136/bmj.e6112  0.68
2012 Lee BY, Bacon KM, Wateska AR, Bottazzi ME, Dumonteil E, Hotez PJ. Modeling the economic value of a Chagas' disease therapeutic vaccine. Human Vaccines & Immunotherapeutics. 8: 1293-301. PMID 22894964 DOI: 10.4161/hv.20966  0.68
2012 Hotez PJ, Asojo OA, Adesina AM. Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. Plos Neglected Tropical Diseases. 6: e1600. PMID 22860138 DOI: 10.1371/journal.pntd.0001600  0.68
2012 Hotez PJ. The Four Horsemen of the Apocalypse: Tropical Medicine in the Fight against Plague, Death, Famine, and War. The American Journal of Tropical Medicine and Hygiene. 87: 3-10. PMID 22764283 DOI: 10.4269/ajtmh.2012.11-0814  0.68
2012 Barry MA, Bezek S, Serpa JA, Hotez PJ, Woc-Colburn L. Neglected infections of poverty in Texas and the rest of the United States: management and treatment options. Clinical Pharmacology and Therapeutics. 92: 170-81. PMID 22760004 DOI: 10.1038/clpt.2012.85  0.68
2012 Moolani Y, Bukhman G, Hotez PJ. Neglected tropical diseases as hidden causes of cardiovascular disease. Plos Neglected Tropical Diseases. 6: e1499. PMID 22745835 DOI: 10.1371/journal.pntd.0001499  0.68
2012 Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Valerio MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. The Journal of Allergy and Clinical Immunology. 130: 13-21. PMID 22742835 DOI: 10.1016/j.jaci.2012.05.029  0.68
2012 Hotez PJ, Dumonteil E, Woc-Colburn L, Serpa JA, Bezek S, Edwards MS, Hallmark CJ, Musselwhite LW, Flink BJ, Bottazzi ME. Chagas disease: "the new HIV/AIDS of the Americas". Plos Neglected Tropical Diseases. 6: e1498. PMID 22666504 DOI: 10.1371/journal.pntd.0001498  0.68
2012 Zhan B, Santiago H, Keegan B, Gillespie P, Xue J, Bethony J, de Oliveira LM, Jiang D, Diemert D, Xiao SH, Jones K, Feng X, Hotez PJ, Bottazzi ME. Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE. Parasite Immunology. 34: 404-11. PMID 22651670 DOI: 10.1111/j.1365-3024.2012.01371.x  0.68
2012 Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. The Journal of Allergy and Clinical Immunology. 130: 169-76.e6. PMID 22633322 DOI: 10.1016/j.jaci.2012.04.027  0.68
2012 Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expression and Purification. 83: 145-51. PMID 22503665 DOI: 10.1016/j.pep.2012.03.013  0.68
2012 Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Human Vaccines & Immunotherapeutics. 8: 765-76. PMID 22495115 DOI: 10.4161/hv.19726  0.68
2012 Hotez PJ, Bottazzi ME, Dumonteil E, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Cravioto MB, Tapia-Conyer R. Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases. Plos Neglected Tropical Diseases. 6: e1497. PMID 22479656 DOI: 10.1371/journal.pntd.0001497  0.68
2012 Pearson MS, Pickering DA, McSorley HJ, Bethony JM, Tribolet L, Dougall AM, Hotez PJ, Loukas A. Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. Plos Neglected Tropical Diseases. 6: e1564. PMID 22428079 DOI: 10.1371/journal.pntd.0001564  0.68
2012 Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. Plos Neglected Tropical Diseases. 6: e1475. PMID 22389729 DOI: 10.1371/journal.pntd.0001475  0.68
2012 Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, ... Hotez PJ, et al. Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine. Infection and Immunity. 80: 1606-14. PMID 22311924 DOI: 10.1128/IAI.06212-11  0.68
2012 Xue J, Zhan B, Guo J, He N, Qiang HQ, Hotez P, Xiao SH. Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Experimental Parasitology. 130: 6-12. PMID 22024448 DOI: 10.1016/j.exppara.2011.10.007  0.68
2012 Molyneux D, Malecela M, Savioli L, Fenwick A, Hotez P. Will increased funding for neglected tropical diseases really make poverty history? - Authors' reply The Lancet. 379: 1098-1100. DOI: 10.1016/S0140-6736(12)60454-1  0.68
2012 Hotez PJ, Bethony JM. Parasitic disease vaccines Vaccines: Sixth Edition. 1154-1160. DOI: 10.1016/B978-1-4557-0090-5.00059-8  0.68
2012 Hotez PJ, Gilman RH. Hookworm and Strongyloides Infections Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. 808-813. DOI: 10.1016/B978-1-4160-4390-4.00109-0  0.68
2012 Hotez P. Foreword to Parasitic Helminths: Targets, Screens, Drugs and Vaccines Parasitic Helminths: Targets, Screens, Drugs and Vaccines. v-vi. DOI: 10.1002/9783527652969  0.68
2012 Dandara C, Adebamowo C, de Vries J, Dove ES, Fisher E, Gibbs RA, Hotez PJ, Kickbusch I, Knoppers BM, Masellis M, Oestergaard MZ, Pang T, Rotimi CN. An idea whose time has come? An African foresight observatory on genomics medicine and data-intensive global science Current Pharmacogenomics and Personalized Medicine. 10: 7-15.  0.68
2011 Hotez PJ, Aksoy S. An interfaith dialogue on the neglected tropical diseases. Plos Neglected Tropical Diseases. 5: e1240. PMID 22206020 DOI: 10.1371/journal.pntd.0001240  0.68
2011 Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine. 29: D104-10. PMID 22188933 DOI: 10.1016/j.vaccine.2011.06.024  0.68
2011 Hotez PJ, Goraleski KA. Neglected tropical diseases and the 2012 US presidential election. Plos Neglected Tropical Diseases. 5: e1431. PMID 22140593 DOI: 10.1371/journal.pntd.0001431  0.68
2011 Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. A history of hookworm vaccine development. Human Vaccines. 7: 1234-44. PMID 22064562 DOI: 10.4161/hv.7.11.18443  0.68
2011 Lobo DA, Velayudhan R, Chatterjee P, Kohli H, Hotez PJ. The neglected tropical diseases of India and South Asia: review of their prevalence, distribution, and control or elimination. Plos Neglected Tropical Diseases. 5: e1222. PMID 22039553 DOI: 10.1371/journal.pntd.0001222  0.68
2011 Hotez PJ, Alibek K. Central Asia's hidden burden of neglected tropical diseases. Plos Neglected Tropical Diseases. 5: e1224. PMID 21980541 DOI: 10.1371/journal.pntd.0001224  0.68
2011 Noblick J, Skolnik R, Hotez PJ. Linking global HIV/AIDS treatments with national programs for the control and elimination of the neglected tropical diseases. Plos Neglected Tropical Diseases. 5: e1022. PMID 21814582 DOI: 10.1371/journal.pntd.0001022  0.68
2011 Hotez PJ, Gurwith M. Europe's neglected infections of poverty. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 15: e611-9. PMID 21763173 DOI: 10.1016/j.ijid.2011.05.006  0.68
2011 Hotez PJ. Unleashing "civilian power": a new American diplomacy through neglected tropical disease control, elimination, research, and development. Plos Neglected Tropical Diseases. 5: e1134. PMID 21738802 DOI: 10.1371/journal.pntd.0001134  0.68
2011 Nair SS, Bommana A, Pakala SB, Ohshiro K, Lyon AJ, Suttiprapa S, Periago MV, Laha T, Hotez PJ, Bethony JM, Sripa B, Brindley PJ, Kumar R. Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology (Baltimore, Md.). 54: 1388-97. PMID 21725997 DOI: 10.1002/hep.24518  0.68
2011 Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. Omics : a Journal of Integrative Biology. 15: 567-77. PMID 21679087 DOI: 10.1089/omi.2010.0150  0.68
2011 Farmer P, Almazor CP, Bahnsen ET, Barry D, Bazile J, Bloom BR, Bose N, Brewer T, Calderwood SB, Clemens JD, Cravioto A, Eustache E, Jérôme G, Gupta N, Harris JB, ... ... Hotez PJ, et al. Meeting cholera's challenge to Haiti and the world: a joint statement on cholera prevention and care. Plos Neglected Tropical Diseases. 5: e1145. PMID 21655350 DOI: 10.1371/journal.pntd.0001145  0.68
2011 Hotez PJ. New antipoverty drugs, vaccines, and diagnostics: a research agenda for the US President's Global Health Initiative (GHI). Plos Neglected Tropical Diseases. 5: e1133. PMID 21655348 DOI: 10.1371/journal.pntd.0001133  0.68
2011 Hotez P. Targeting hookworm, chagas, and other neglected diseases Health Affairs. 30: 1088. PMID 21653961 DOI: 10.1377/hlthaff.2011.0513  0.68
2011 Hotez P. A handful of 'antipoverty' vaccines exist for neglected diseases, but the world's poorest billion people need more. Health Affairs (Project Hope). 30: 1080-7. PMID 21653960 DOI: 10.1377/hlthaff.2011.0317  0.68
2011 Hotez PJ, Mistry N, Rubinstein J, Sachs JD. Integrating neglected tropical diseases into AIDS, tuberculosis, and malaria control. The New England Journal of Medicine. 364: 2086-9. PMID 21631320 DOI: 10.1056/NEJMp1014637  0.68
2011 Hotez PJ. Neglected tropical diseases in the Catholic world. Plos Neglected Tropical Diseases. 5: e1132. PMID 21541361 DOI: 10.1371/journal.pntd.0001132  0.68
2011 Nair SS, Bommana A, Bethony JM, Lyon AJ, Ohshiro K, Pakala SB, Rinaldi G, Keegan B, Suttiprapa S, Periago MV, Hotez PJ, Brindley PJ, Kumar R. The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology (Baltimore, Md.). 54: 285-95. PMID 21488078 DOI: 10.1002/hep.24354  0.68
2011 Hotez PJ. America's most distressed areas and their neglected infections: the United States Gulf Coast and the District of Columbia. Plos Neglected Tropical Diseases. 5: e843. PMID 21468312 DOI: 10.1371/journal.pntd.0000843  0.68
2011 Alexander N, Cundill B, Sabatelli L, Bethony JM, Diemert D, Hotez P, Smith PG, Rodrigues LC, Brooker S. Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine. 29: 3686-94. PMID 21435404 DOI: 10.1016/j.vaccine.2011.03.026  0.68
2011 Jex AR, Lim YA, Bethony JM, Hotez PJ, Young ND, Gasser RB. Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Advances in Parasitology. 74: 231-65. PMID 21295679 DOI: 10.1016/B978-0-12-385897-9.00004-5  0.68
2011 Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P. Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 177: 42-8. PMID 21251931 DOI: 10.1016/j.molbiopara.2011.01.008  0.68
2011 Bethony JM, Cole RN, Guo X, Kamhawi S, Lightowlers MW, Loukas A, Petri W, Reed S, Valenzuela JG, Hotez PJ. Vaccines to combat the neglected tropical diseases. Immunological Reviews. 239: 237-70. PMID 21198676 DOI: 10.1111/j.1600-065X.2010.00976.x  0.68
2011 Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica. 120: S158-68. PMID 20655862 DOI: 10.1016/j.actatropica.2010.07.006  0.68
2011 Hotez PJ. Hookworm Infections Tropical Infectious Diseases. 799-804. DOI: 10.1016/B978-0-7020-3935-5.00116-6  0.68
2010 Bourhy H, Dautry-Varsat A, Hotez PJ, Salomon J. Rabies, still neglected after 125 years of vaccination. Plos Neglected Tropical Diseases. 4: e839. PMID 21152052 DOI: 10.1371/journal.pntd.0000839  0.68
2010 Waldor MK, Hotez PJ, Clemens JD. A national cholera vaccine stockpile--a new humanitarian and diplomatic resource. The New England Journal of Medicine. 363: 2279-82. PMID 21105832 DOI: 10.1056/NEJMp1012300  0.68
2010 Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A. Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews. Microbiology. 8: 814-26. PMID 20948553 DOI: 10.1038/nrmicro2438  0.68
2010 Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Review of Vaccines. 9: 1219-30. PMID 20923271 DOI: 10.1586/erv.10.107  0.68
2010 Hotez PJ. Neglected tropical disease control in the "post-American world". Plos Neglected Tropical Diseases. 4. PMID 20824178 DOI: 10.1371/journal.pntd.0000812  0.68
2010 Hotez PJ, Engels D, Fenwick A, Savioli L. Africa is desperate for praziquantel. Lancet. 376: 496-8. PMID 20709217 DOI: 10.1016/S0140-6736(10)60879-3  0.68
2010 Brooker S, Hotez PJ, Bundy DA. The global atlas of helminth infection: mapping the way forward in neglected tropical disease control. Plos Neglected Tropical Diseases. 4: e779. PMID 20668545 DOI: 10.1371/journal.pntd.0000779  0.68
2010 Hotez PJ, Ehrenberg JP. Escalating the global fight against neglected tropical diseases through interventions in the Asia Pacific region. Advances in Parasitology. 72: 31-53. PMID 20624527 DOI: 10.1016/S0065-308X(10)72002-9  0.68
2010 Hotez P. A national school of tropical medicine and neglected infections of poverty for North America. Plos Neglected Tropical Diseases. 4: e735. PMID 20614018 DOI: 10.1371/journal.pntd.0000735  0.68
2010 Hotez PJ, Pecoul B. "Manifesto" for advancing the control and elimination of neglected tropical diseases. Plos Neglected Tropical Diseases. 4: e718. PMID 20520793 DOI: 10.1371/journal.pntd.0000718  0.68
2010 Spiegel JM, Dharamsi S, Wasan KM, Yassi A, Singer B, Hotez PJ, Hanson C, Bundy DA. Which new approaches to tackling neglected tropical diseases show promise? Plos Medicine. 7: e1000255. PMID 20502599 DOI: 10.1371/journal.pmed.1000255  0.68
2010 Hotez PJ. Nuclear weapons and neglected diseases: the "ten-thousand-to-one gap". Plos Neglected Tropical Diseases. 4: e680. PMID 20436916 DOI: 10.1371/journal.pntd.0000680  0.68
2010 Hotez P, Stillwaggon E, McDonald M, Todman L, DiGrazia L. National summit on neglected infections of poverty in the United States. Emerging Infectious Diseases. 16: e1. PMID 20409362 DOI: 10.3201/eid1605.091863  0.68
2010 Pearson MS, Pickering DA, Tribolet L, Cooper L, Mulvenna J, Oliveira LM, Bethony JM, Hotez PJ, Loukas A. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. The Journal of Infectious Diseases. 201: 1561-9. PMID 20367477 DOI: 10.1086/651953  0.68
2010 Hotez PJ. Peace through vaccine diplomacy. Science (New York, N.Y.). 327: 1301. PMID 20223952 DOI: 10.1126/science.1189028  0.68
2010 Kishore SP, Tavera G, Hotez PJ. The global health crisis and our nation's research universities. Plos Neglected Tropical Diseases. 4: e635. PMID 20186327 DOI: 10.1371/journal.pntd.0000635  0.68
2010 Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, ... ... Hotez P, et al. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infection and Immunity. 78: 1552-63. PMID 20145100 DOI: 10.1128/IAI.00848-09  0.68
2010 Hotez PJ. Neglected infections of poverty among the indigenous peoples of the arctic. Plos Neglected Tropical Diseases. 4: e606. PMID 20126272 DOI: 10.1371/journal.pntd.0000606  0.68
2010 Asojo OA, Goud GN, Zhan B, Ordonez K, Sedlacek M, Homma K, Deumic V, Gupta R, Brelsford J, Price MK, Ngamelue MN, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 172-6. PMID 20124715 DOI: 10.1107/S1744309109051616  0.68
2010 Hotez PJ. A plan to defeat neglected tropical diseases. Scientific American. 302: 90-4, 96. PMID 20063641 DOI: 10.1038/scientificamerican0110-74  0.68
2010 Franco-Paredes C, Ko AI, Aksoy S, Hotez PJ. A new clinical section in PLoS Neglected Tropical Diseases Plos Neglected Tropical Diseases. 4. DOI: 10.1371/journal.pntd.0000760  0.68
2009 Hotez PJ. Empowering women and improving female reproductive health through control of neglected tropical diseases. Plos Neglected Tropical Diseases. 3: e559. PMID 19936248 DOI: 10.1371/journal.pntd.0000559  0.68
2009 Hotez P. Neglected diseases amid wealth in the United States and Europe. Health Affairs (Project Hope). 28: 1720-5. PMID 19887412 DOI: 10.1377/hlthaff.28.6.1720  0.68
2009 Musgrove P, Hotez PJ. Turning neglected tropical diseases into forgotten maladies. Health Affairs (Project Hope). 28: 1691-706. PMID 19887410 DOI: 10.1377/hlthaff.28.6.1691  0.68
2009 Hotez PJ. The neglected tropical diseases and their devastating health and economic impact on the member nations of the Organisation of the Islamic Conference. Plos Neglected Tropical Diseases. 3: e539. PMID 19859530 DOI: 10.1371/journal.pntd.0000539  0.68
2009 Hotez PJ, Fenwick A. Schistosomiasis in Africa: an emerging tragedy in our new global health decade. Plos Neglected Tropical Diseases. 3: e485. PMID 19787054 DOI: 10.1371/journal.pntd.0000485  0.68
2009 Hotez PJ, Kamath A. Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden. Plos Neglected Tropical Diseases. 3: e412. PMID 19707588 DOI: 10.1371/journal.pntd.0000412  0.68
2009 Hotez PJ. A constitutional amendment for deworming. Plos Neglected Tropical Diseases. 3: e454. PMID 19707577 DOI: 10.1371/journal.pntd.0000454  0.68
2009 Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P. New vaccines for developing countries: will it be feast or famine? American Journal of Law & Medicine. 35: 311-22. PMID 19697751  0.68
2009 Franco-Paredes C, Bottazzi ME, Hotez PJ. The unfinished public health agenda of chagas disease in the era of globalization. Plos Neglected Tropical Diseases. 3: e470. PMID 19582139 DOI: 10.1371/journal.pntd.0000470  0.68
2009 Stoever K, Molyneux D, Hotez P, Fenwick A. HIV/AIDS, schistosomiasis, and girls. Lancet. 373: 2025-6. PMID 19524778 DOI: 10.1016/S0140-6736(09)61111-9  0.68
2009 Hotez PJ, Fenwick A, Kjetland EF. Africa's 32 cents solution for HIV/AIDS. Plos Neglected Tropical Diseases. 3: e430. PMID 19479041 DOI: 10.1371/journal.pntd.0000430  0.68
2009 Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. The Journal of Infectious Diseases. 199: 904-12. PMID 19434933 DOI: 10.1086/597048  0.68
2009 Hotez PJ, Fenwick A, Savioli L, Molyneux DH. Rescuing the bottom billion through control of neglected tropical diseases. Lancet. 373: 1570-5. PMID 19410718 DOI: 10.1016/S0140-6736(09)60233-6  0.68
2009 Hotez PJ. One world health: neglected tropical diseases in a flat world. Plos Neglected Tropical Diseases. 3: e405. PMID 19399165 DOI: 10.1371/journal.pntd.0000405  0.68
2009 Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, ... ... Hotez PJ, et al. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3007-19. PMID 19380510 DOI: 10.1096/fj.09-131433  0.68
2009 Hotez PJ, Wilkins PP. Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance? Plos Neglected Tropical Diseases. 3: e400. PMID 19333373 DOI: 10.1371/journal.pntd.0000400  0.68
2009 Hotez PJ. Mass drug administration and integrated control for the world's high-prevalence neglected tropical diseases. Clinical Pharmacology and Therapeutics. 85: 659-64. PMID 19322166 DOI: 10.1038/clpt.2009.16  0.68
2009 Hotez PJ, Brown AS. Neglected tropical disease vaccines. Biologicals : Journal of the International Association of Biological Standardization. 37: 160-4. PMID 19278869 DOI: 10.1016/j.biologicals.2009.02.008  0.68
2009 Hotez PJ, Thompson TG. Waging peace through neglected tropical disease control: a US foreign policy for the bottom billion. Plos Neglected Tropical Diseases. 3: e346. PMID 19172176 DOI: 10.1371/journal.pntd.0000346  0.68
2009 Molyneux DH, Hotez PJ, Fenwick A, Newman RD, Greenwood B, Sachs J. Neglected tropical diseases and the Global Fund. Lancet. 373: 296-7. PMID 19167564 DOI: 10.1016/S0140-6736(09)60089-1  0.68
2009 Hotez PJ, Aksoy S. PLoS neglected tropical diseases: Two years of providing access to innovation for the world's poor... and counting Plos Neglected Tropical Diseases. 3. DOI: 10.1371/journal.pntd.0000494  0.68
2009 Hotez PJ, Yamey G. The evolving scope of PLoS Neglected Tropical Diseases Plos Neglected Tropical Diseases. 3. DOI: 10.1371/journal.pntd.0000379  0.68
2009 Hotez P. Devastating global impact of neglected tropical diseases Microbe. 4.  0.68
2008 Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. Plos Neglected Tropical Diseases. 2: e300. PMID 18820747 DOI: 10.1371/journal.pntd.0000300  0.32
2008 Zhan B, Gupta R, Wong SP, Bier S, Jiang D, Goud G, Hotez P. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 162: 142-8. PMID 18804124 DOI: 10.1016/j.molbiopara.2008.08.008  0.32
2008 Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines. 7: 745-52. PMID 18665774 DOI: 10.1586/14760584.7.6.745  0.68
2008 Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Molecular and Biochemical Parasitology. 160: 90-9. PMID 18501979 DOI: 10.1016/j.molbiopara.2008.04.008  0.32
2008 Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 26: 2408-17. PMID 18396361 DOI: 10.1016/j.vaccine.2008.02.049  0.68
2008 Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. The Journal of Clinical Investigation. 118: 1311-21. PMID 18382743 DOI: 10.1172/JCI34261  0.68
2008 Diemert DJ, Bethony JM, Hotez PJ. Hookworm vaccines. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 46: 282-8. PMID 18171264 DOI: 10.1086/524070  0.32
2008 Mendez S, D' Samuel A, Antoine AD, Ahn S, Hotez P. Use of the air pouch model to investigate immune responses to a hookworm vaccine containing the Na-ASP-2 protein in rats. Parasite Immunology. 30: 53-6. PMID 18086017 DOI: 10.1111/j.1365-3024.2007.00994.x  0.68
2008 Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Experimental Parasitology. 118: 32-40. PMID 17645877 DOI: 10.1016/j.exppara.2007.05.010  0.48
2007 Brooker S, Akhwale W, Pullan R, Estambale B, Clarke SE, Snow RW, Hotez PJ. Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. The American Journal of Tropical Medicine and Hygiene. 77: 88-98. PMID 18165479  0.68
2007 Inan M, Fanders SA, Zhang W, Hotez PJ, Zhan B, Meagher MM. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods in Molecular Biology (Clifton, N.J.). 389: 65-76. PMID 17951635 DOI: 10.1007/978-1-59745-456-8_5  0.68
2007 Asojo OA, Homma K, Sedlacek M, Ngamelue M, Goud GN, Zhan B, Deumic V, Asojo O, Hotez PJ. X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. Bmc Structural Biology. 7: 42. PMID 17594497 DOI: 10.1186/1472-6807-7-42  0.32
2007 Feng J, Zhan B, Liu Y, Liu S, Williamson A, Goud G, Loukas A, Hotez P. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 152: 132-8. PMID 17280728 DOI: 10.1016/j.molbiopara.2007.01.001  0.32
2007 Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clinical and Vaccine Immunology : Cvi. 14: 281-7. PMID 17267592 DOI: 10.1128/CVI.00404-06  0.68
2007 Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, Hotez PJ, Correa-Oliveira R, Rodrigues LC, Bethony JM. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 146-54. PMID 17027054 DOI: 10.1016/j.trstmh.2006.05.012  0.32
2006 Bethony JM, Loukas A, Hotez PJ, Knox DP. Vaccines against blood-feeding nematodes of humans and livestock. Parasitology. 133: S63-79. PMID 17274849 DOI: 10.1017/S0031182006001818  0.32
2006 Loukas A, Bethony J, Brooker S, Hotez P. Hookworm vaccines: past, present, and future. The Lancet. Infectious Diseases. 6: 733-41. PMID 17067922 DOI: 10.1016/S1473-3099(06)70630-2  0.32
2006 Hotez PJ, Ferris MT. The antipoverty vaccines. Vaccine. 24: 5787-99. PMID 16759763 DOI: 10.1016/j.vaccine.2006.05.008  0.68
2006 Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A. New technologies for the control of human hookworm infection. Trends in Parasitology. 22: 327-31. PMID 16709466 DOI: 10.1016/j.pt.2006.05.004  0.32
2006 Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, Hotez PJ. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 367: 1521-32. PMID 16679166 DOI: 10.1016/S0140-6736(06)68653-4  0.32
2006 Bottazzi ME, Miles AP, Diemert D, Hotez PJ. An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases. Expert Review of Vaccines. 5: 189-98. PMID 16608419 DOI: 10.1586/14760584.5.2.189  0.32
2006 Hotez P, Gupta R, Mahoney R, Poste G. Incorporating appropriate technology into North American schools of public health. Revista Panamericana De Salud PúBlica = Pan American Journal of Public Health. 19: 118-23. PMID 16551386  0.68
2006 Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A. Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infection and Immunity. 74: 961-7. PMID 16428741 DOI: 10.1128/IAI.74.2.961-967.2006  0.68
2006 Fleming FM, Brooker S, Geiger SM, Caldas IR, Correa-Oliveira R, Hotez PJ, Bethony JM. Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Tropical Medicine & International Health : Tm & Ih. 11: 56-64. PMID 16398756 DOI: 10.1111/j.1365-3156.2005.01541.x  0.32
2006 Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. The Journal of Infectious Diseases. 193: 155-62. PMID 16323144 DOI: 10.1086/498528  0.32
2006 Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM. Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine. 24: 501-9. PMID 16140437 DOI: 10.1016/j.vaccine.2005.07.091  0.68
2005 Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S. Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Human Vaccines. 1: 123-8. PMID 17012856  0.32
2005 Asojo OA, Loukas A, Inan M, Barent R, Huang J, Plantz B, Swanson A, Gouthro M, Meagher MM, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 391-4. PMID 16511050 DOI: 10.1107/S1744309105007748  0.68
2005 Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. Plos Medicine. 2: e295. PMID 16231975 DOI: 10.1371/journal.pmed.0020295  0.32
2005 Xue J, Hui-Qing Q, Jun-Ming Y, Fujiwara R, Zhan B, Hotez P, Shu-Hua X. Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Experimental Parasitology. 111: 219-23. PMID 16198341 DOI: 10.1016/j.exppara.2005.08.002  0.32
2005 Zhan B, Liu S, Perally S, Xue J, Fujiwara R, Brophy P, Xiao S, Liu Y, Feng J, Williamson A, Wang Y, Bueno LL, Mendez S, Goud G, Bethony JM, ... ... Hotez PJ, et al. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infection and Immunity. 73: 6903-11. PMID 16177370 DOI: 10.1128/IAI.73.10.6903-6911.2005  0.68
2005 Hotez PJ, Arora S, Bethony J, Bottazzi ME, Loukas A, Correa-Oliveira R, Brooker S. Helminth infections of children: prospects for control. Advances in Experimental Medicine and Biology. 568: 135-44. PMID 16108129 DOI: 10.1007/0-387-25342-4_9  0.32
2005 Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, ... ... Hotez PJ, et al. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 23: 4754-64. PMID 16054275 DOI: 10.1016/j.vaccine.2005.04.040  0.48
2005 Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1743-5. PMID 16037096 DOI: 10.1096/fj.05-3936fje  0.68
2005 Morel CM, Acharya T, Broun D, Dangi A, Elias C, Ganguly NK, Gardner CA, Gupta RK, Haycock J, Heher AD, Hotez PJ, Kettler HE, Keusch GT, Krattiger AF, Kreutz FT, et al. Health innovation networks to help developing countries address neglected diseases. Science (New York, N.Y.). 309: 401-4. PMID 16020723 DOI: 10.1126/science.1115538  0.68
2005 Mendez S, Valenzuela JG, Wu W, Hotez PJ. Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster. Infection and Immunity. 73: 3402-7. PMID 15908367 DOI: 10.1128/IAI.73.6.3402-3407.2005  0.68
2005 Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 23: 3123-30. PMID 15837211 DOI: 10.1016/j.vaccine.2004.12.022  0.48
2005 Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hookworm: "the great infection of mankind". Plos Medicine. 2: e67. PMID 15783256 DOI: 10.1371/journal.pmed.0020067  0.32
2005 Asojo OA, Goud G, Dhar K, Loukas A, Zhan B, Deumic V, Liu S, Borgstahl GE, Hotez PJ. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. Journal of Molecular Biology. 346: 801-14. PMID 15713464 DOI: 10.1016/j.jmb.2004.12.023  0.32
2004 Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S. Hookworm infection. The New England Journal of Medicine. 351: 799-807. PMID 15317893 DOI: 10.1056/NEJMra032492  0.68
2004 Zhan B, Wang Y, Liu Y, Williamson A, Loukas A, Hawdon JM, Xue HC, Xiao SH, Hotez PJ. Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. International Journal For Parasitology. 34: 1037-45. PMID 15313130 DOI: 10.1016/j.ijpara.2004.04.015  0.68
2004 Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. A pore-forming haemolysin from the hookworm, Ancylostoma caninum. International Journal For Parasitology. 34: 1029-35. PMID 15313129 DOI: 10.1016/j.ijpara.2004.04.013  0.32
2004 Hsieh GC, Loukas A, Wahl AM, Bhatia M, Wang Y, Williamson AL, Kehn KW, Maruyama H, Hotez PJ, Leitenberg D, Bethony J, Constant SL. A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 173: 2699-704. PMID 15294988  0.68
2004 Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. The Journal of Biological Chemistry. 279: 35950-7. PMID 15199048 DOI: 10.1074/jbc.M405842200  0.68
2004 Loukas A, Bethony JM, Williamson AL, Goud GN, Mendez S, Zhan B, Hawdon JM, Elena Bottazzi M, Brindley PJ, Hotez PJ. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. The Journal of Infectious Diseases. 189: 1952-61. PMID 15122534 DOI: 10.1086/386346  0.68
2004 Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, ... ... Hotez PJ, et al. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. The Journal of Infectious Diseases. 189: 919-29. PMID 14976610 DOI: 10.1086/381901  0.68
2003 Hotez PJ, Ashcom J, Zhan B, Bethony J, Loukas A, Hawdon J, Wang Y, Jin Q, Jones KC, Dobardzic A, Dobardzic R, Bolden J, Essiet I, Brandt W, Russell PK, et al. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. The Journal of Parasitology. 89: 853-5. PMID 14533704 DOI: 10.1645/GE-46R  0.68
2003 Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, et al. Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. International Journal For Parasitology. 33: 1245-58. PMID 13678639 DOI: 10.1016/S0020-7519(03)00158-9  0.68
2003 Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Digestive proteases of blood-feeding nematodes. Trends in Parasitology. 19: 417-23. PMID 12957519 DOI: 10.1016/S1471-4922(03)00189-2  0.68
2003 Zhan B, Liu Y, Badamchian M, Williamson A, Feng J, Loukas A, Hawdon JM, Hotez PJ. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. International Journal For Parasitology. 33: 897-907. PMID 12906874 DOI: 10.1016/S0020-7519(03)00111-5  0.68
2003 Zhu XP, Yang J, Yang YP, Boireau P, Zhan B, Feng JJ, Hotez P. [Prokaryotic expression and characterization of an antigenic gene of adult Trichinella spiralis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 21: 16-9. PMID 12884582  0.32
2003 Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. International Journal For Parasitology. 33: 621-40. PMID 12782060 DOI: 10.1016/S0020-7519(03)00057-2  0.68
2003 Basavaraju SV, Basavaraju S, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Molecular and Biochemical Parasitology. 126: 63-71. PMID 12554085 DOI: 10.1016/S0166-6851(02)00253-0  0.68
2003 Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. The Journal of Infectious Diseases. 187: 484-94. PMID 12552433 DOI: 10.1086/367708  0.68
2002 Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 1336-44. PMID 12439796 DOI: 10.1086/344268  0.68
2002 Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1458-60. PMID 12205047 DOI: 10.1096/fj.02-0181fje  0.68
2002 Hotez PJ, Ashcom J, Bin Z, Bethony J, Williamson A, Hawdon JM, Jianjun F, Dobardzic A, Rizo I, Bolden J, Jin Q, Yan W, Dobardzic R, Chung-Debose S, Crowell M, et al. Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. The Journal of Parasitology. 88: 684-90. PMID 12197114 DOI: 10.1645/0022-3395(2002)088[0684:EOVWRF]2.0.CO;2  0.68
2002 Zhan B, Badamchian M, Meihua B, Ashcom J, Feng J, Hawdon J, Shuhua X, Hotez PJ. Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. The American Journal of Tropical Medicine and Hygiene. 66: 238-44. PMID 12139214  0.68
2002 Zhan B, Hotez PJ, Wang Y, Hawdon JM. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Molecular and Biochemical Parasitology. 120: 291-6. PMID 11897134  0.68
2002 Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Molecular and Biochemical Parasitology. 119: 107-16. PMID 11755191 DOI: 10.1016/S0166-6851(01)00409-1  0.68
2001 Shuhua X, Hotez PJ, Binggui S, Sen L, Huiqing Q, Haichou X, Bin Z, Zheng F. Electron and light microscopy of neutrophil responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Parasitology International. 50: 241-8. PMID 11719110  0.68
2001 Gandhi NS, Jizhang C, Khoshnood K, Fuying X, Shanwen L, Yaoruo L, Bin Z, Haechou X, Chongjin T, Yan W, Wensen W, Dungxing H, Chong C, Shuhua X, Hawdon JM, ... Hotez PJ, et al. Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. The Journal of Parasitology. 87: 739-43. PMID 11534635 DOI: 10.1645/0022-3395(2001)087[0739:EONAHI]2.0.CO;2  0.68
2000 Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Xiao SH, Li TH, Feng Z, Hotez P. Construction and analysis of cDNA library of Necator americanus third stage larvae. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 18: 26-8. PMID 12567467  0.68
2000 Haichou X, Yan W, Shuhua X, Sen L, Yong W, Guangjin S, Weituo W, Bin Z, Drake L, Zheng F, Hotez PJ. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 736-41. PMID 11414422  0.68
2000 Lili Z, Bingxiang Z, Hong T, Shuhua X, Hotez P, Bing Z, Yangzhong L, Ying L, Haichou X, Hawdon J, Hui Y, Huizhen W, Zhen F. Epidemiology of human geohelminth infections (ascariasis, trichuriasis and necatoriasis) in Lushui and Puer Counties, Yunnan Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 448-53. PMID 11288999  0.68
2000 Qiang S, Bin Z, Shu-hua X, Zheng F, Hotez P, Hawdon JM. Variation between ASP-1 molecules from Ancylostoma caninum in China and the United States. The Journal of Parasitology. 86: 181-5. PMID 10701589 DOI: 10.1645/0022-3395(2000)086[0181:VBAMFA]2.0.CO;2  0.68
2000 Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G. A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proceedings of the National Academy of Sciences of the United States of America. 97: 460-5. PMID 10618440 DOI: 10.1073/pnas.97.1.460  0.68
2000 Sen L, Ghosh K, Bin Z, Qiang S, Thompson MG, Hawdon JM, Koski RA, Shuhua X, Hotez PJ. Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 18: 1096-102. PMID 10590331 DOI: 10.1016/S0264-410X(99)00371-0  0.68
1999 Li T, Zhan B, Hawdon JM, Gong X, Xiao S, Shan Q, Feng Z, Hotez PJ. [Sequencing of cytochrome C oxidase 1 gene of Ancylostoma duodenale and Necator americanus]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 17: 81-3. PMID 12563786  0.68
1999 Yang Y, Xiao S, Ren H, Wu J, Feng Z, Hotez PJ. Cutaneous and subcutaneous mast cell and eosinophil responses after challenge in mice vaccinated with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1020-3. PMID 11721464  0.48
1999 Xiao S, Ren H, Yang Y, Liu S, Qiang H, Xue H, Feng Z, Hotez PJ. Length of protection by murine vaccination with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1129-32. PMID 11721454  0.48
1999 Xue H, Liu S, Ren H, Qiang H, Xiao S, Feng Z, Hotez P. Enzyme-linked immunoelectrotransfer blotting analysis of human serologic responses to infective hookworm larval antigen. Chinese Medical Journal. 112: 249-50. PMID 11593560  0.48
1999 Yong W, Guangjin S, Weitu W, Shuhua X, Hotez PJ, Qiyang L, Haichou X, Xiaomei Y, Xiaoming L, Bin Z, Hawdon JM, Li C, Hong J, Chunmei H, Zheng F. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. The Southeast Asian Journal of Tropical Medicine and Public Health. 30: 692-7. PMID 10928362  0.68
1999 Hotez PJ, Ghosh K, Hawdon JM, Narasimhan S, Jones B, Shuhua X, Sen L, Bin Z, Haechou X, Hainan R, Heng W, Koski RA. Experimental approaches to the development of a recombinant hookworm vaccine. Immunological Reviews. 171: 163-71. PMID 10582170 DOI: 10.1111/j.1600-065X.1999.tb01347.x  0.68
1999 Changhua L, Xiaorong Z, Dongchuan Q, Shuhua X, Hotez PJ, Defu Z, Hulian Z, Mingden L, Hainan R, Bing Z, Haichou X, Hawdon J, Zheng F. Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China. Acta Tropica. 73: 243-9. PMID 10546842 DOI: 10.1016/S0001-706X(99)00035-2  0.68
1999 Labiano-Abello N, Canese J, Velazquez ME, Hawdon JM, Wilson ML, Hotez PJ. Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study. MemóRias Do Instituto Oswaldo Cruz. 94: 583-6. PMID 10464397  0.68
1999 Hawdon JM, Narasimhan S, Hotez PJ. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Molecular and Biochemical Parasitology. 99: 149-65. PMID 10340481 DOI: 10.1016/S0166-6851(99)00011-0  0.68
1999 Bin Z, Hawdon J, Qiang S, Hainan R, Huiqing Q, Wei H, Shu-Hua X, Tiehua L, Xing G, Zheng F, Hotez P. Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Molecular and Biochemical Parasitology. 98: 143-9. PMID 10029316 DOI: 10.1016/S0166-6851(98)00157-1  0.68
1998 Fenghua S, Zhongxing W, Yixing Q, Hangqun C, Haichou X, Hainan R, Shuhua X, Bin Z, Hawdon JM, Zheng F, Hotez PJ. Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 29: 605-10. PMID 10437966  0.68
1998 Xiao S, Ren H, Yang Y, Xue H, Qiang H, Liu S, Feng Z, Hotez PJ. Protective immunity in mice elicited by living infective third-stage hookworm larvae (Shanghai strain of Ancylostoma caninum). Chinese Medical Journal. 111: 43-8. PMID 10322652  0.48
1998 Shuhua X, Hotez PJ, Binggui S, Sen L, Hainan R, Haichou X, Huiqing Q, Zheng F. Electron and light microscopy of peritoneal cellular immune responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Tropica. 71: 155-67. PMID 9821464  0.68
1998 Pao W, Duncan KO, Bolognia JL, Carroll CB, Hotez PJ, Bessen DE. Numerous eruptive lesions of panniculitis associated with group A streptococcus bacteremia in an immunocompetent child. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 27: 430-3. PMID 9770136  0.68
1997 Hotez PJ, Ghosh K, Hawdon J, Narasimhan S, Jones B, Bethony J. Vaccines for hookworm infection. The Pediatric Infectious Disease Journal. 16: 935-40. PMID 9380467 DOI: 10.1097/00006454-199710000-00006  0.68
1996 Ghosh K, Hawdon J, Hotez P. Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae. The Journal of Infectious Diseases. 174: 1380-3. PMID 8940240  0.68
1996 Hawdon JM, Hotez PJ. Hookworm: developmental biology of the infectious process. Current Opinion in Genetics & Development. 6: 618-23. PMID 8939719 DOI: 10.1016/S0959-437X(96)80092-X  0.68
1996 Hotez PJ, Hawdon JM, Cappello M, Jones BF, Ghosh K, Volvovitz F, Xiao SH. Molecular approaches to vaccinating against hookworm disease. Pediatric Research. 40: 515-21. PMID 8888276 DOI: 10.1203/00006450-199610000-00001  0.68
1996 Cappello M, Hawdon JM, Jones BF, Kennedy WP, Hotez PJ. Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli. Molecular and Biochemical Parasitology. 80: 113-7. PMID 8885227 DOI: 10.1016/0166-6851(96)02658-8  0.68
1996 Hawdon JM, Jones BF, Hoffman DR, Hotez PJ. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. The Journal of Biological Chemistry. 271: 6672-8. PMID 8636085  0.68
1995 Hawdon JM, Jones BF, Perregaux MA, Hotez PJ. Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro. Experimental Parasitology. 80: 205-11. PMID 7895832 DOI: 10.1006/expr.1995.1025  0.68
1995 Hawdon JM, Jones BF, Hotez PJ. Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae. Molecular and Biochemical Parasitology. 69: 127-30. PMID 7723782 DOI: 10.1016/0166-6851(94)00203-Y  0.68
1995 Hotez PJ, Hawdon JM, Cappello M, Jones BF, Pritchard DI. Molecular pathobiology of hookworm infection. Infectious Agents and Disease. 4: 71-5. PMID 7613730  0.68
1993 Hotez P, Hawdon J, Schad GA. Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans Daf-c paradigm. Parasitology Today (Personal Ed.). 9: 23-6. PMID 15463660 DOI: 10.1016/0169-4758(93)90159-D  0.68
1992 Hotez PJ, Narasimhan S, Haggerty J, Milstone L, Bhopale V, Schad GA, Richards FF. Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans. Infection and Immunity. 60: 1018-23. PMID 1541516  0.68
1987 Hotez PJ, Le Trang N, Cerami A. Hookworm antigens: the potential for vaccination. Parasitology Today (Personal Ed.). 3: 247-9. PMID 15462967  1
1985 Cerami A, Ikeda Y, Le Trang N, Hotez PJ, Beutler B. Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor). Immunology Letters. 11: 173-7. PMID 3910566  1
1985 Hotez PJ, Trang NL, McKerrow JH, Cerami A. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum. The Journal of Biological Chemistry. 260: 7343-8. PMID 3888998  1
1984 Hotez PJ, Le Trang N, Fairlamb AH, Cerami A. Lipoprotein lipase suppression in 3T3-L1 cells by a haematoprotozoan-induced mediator from peritoneal exudate cells. Parasite Immunology. 6: 203-9. PMID 6377200  1
1983 Hotez PJ, Cerami A. Secretion of a proteolytic anticoagulant by Ancylostoma hookworms. The Journal of Experimental Medicine. 157: 1594-603. PMID 6343546  1
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