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Peter Hotez, M.D., Ph.D - Publications

Affiliations: 
Molecular Virology and Microbiology Baylor College of Medicine, Houston, TX 
Area:
Hookworm, Neglected Tropical Diseases
Website:
https://www.bcm.edu/people-search/peter-hotez-23229
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Year Citation  Score
2023 Puchner KP, Bottazzi ME, Periago V, Grobusch M, Maizels R, McCarthy J, Lee B, Gaspari E, Diemert D, Hotez P. Vaccine value profile for Hookworm. Vaccine. PMID 37863671 DOI: 10.1016/j.vaccine.2023.05.013  0.386
2023 Diemert DJ, Correa-Oliveira R, Fraga CG, Talles F, Silva MR, Patel SM, Galbiati S, Kennedy JK, Lundeen JS, Gazzinelli MF, Li G, Hoeweler L, Deye GA, Bottazzi ME, Hotez PJ, et al. A randomized, controlled Phase 1b trial of the Sm-TSP-2 Vaccine for intestinal schistosomiasis in healthy Brazilian adults living in an endemic area. Plos Neglected Tropical Diseases. 17: e0011236. PMID 36996185 DOI: 10.1371/journal.pntd.0011236  0.312
2022 Betouke Ongwe ME, Mouwenda YD, Stam KA, Kremsner PG, Lell B, Diemert D, Bethony J, Bottazzi ME, Hotez PJ, Leeuwen RV, Grobusch MP, Adegnika AA, Mayboroda OA, Yazdanbakhsh M. Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon. Plos One. 17: e0275013. PMID 36155987 DOI: 10.1371/journal.pone.0275013  0.349
2022 Diemert DJ, Zumer M, Campbell D, Grahek S, Li G, Peng J, Elena Bottazzi M, Hotez P, Bethony J. Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults. Vaccine. 40: 6084-6092. PMID 36114129 DOI: 10.1016/j.vaccine.2022.09.017  0.34
2022 Zhan B, Bottazzi ME, Hotez PJ, Lustigman S. Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With . Frontiers in Cellular and Infection Microbiology. 12: 869039. PMID 35444961 DOI: 10.3389/fcimb.2022.869039  0.375
2021 Gazzinelli-Guimarães AC, Nogueira DS, Amorim CCO, Oliveira FMS, Coqueiro-Dos-Santos A, Carvalho SAP, Kraemer L, Barbosa FS, Fraga VG, Santos FV, de Castro JC, Russo RC, Akamatsu MA, Ho PL, Bottazzi ME, ... Hotez PJ, et al. ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Infection. Frontiers in Immunology. 12: 788185. PMID 34992603 DOI: 10.3389/fimmu.2021.788185  0.332
2021 Loukas A, Maizels RM, Hotez PJ. The yin and yang of human soil-transmitted helminth infections. International Journal For Parasitology. 51: 1243-1253. PMID 34774540 DOI: 10.1016/j.ijpara.2021.11.001  0.342
2021 Mouwenda YD, Betouke Ongwe ME, Sonnet F, Stam KA, Labuda LA, De Vries S, Grobusch MP, Zinsou FJ, Honkpehedji YJ, Dejon Agobe JC, Diemert DJ, van Leeuwen R, Bottazzi ME, Hotez PJ, Kremsner PG, et al. Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon. Plos Neglected Tropical Diseases. 15: e0009732. PMID 34597297 DOI: 10.1371/journal.pntd.0009732  0.33
2020 de Castro JC, de Almeida LV, Cardoso MS, Oliveira FMS, Nogueira DS, Reis-Cunha JL, Magalhaes LMD, Zhan B, Bottazzi ME, Hotez PJ, Bueno LL, Bartholomeu DC, Fujiwara RT. Vaccination with chimeric protein induces protection in murine model against ascariasis. Vaccine. PMID 33248854 DOI: 10.1016/j.vaccine.2020.11.046  0.345
2020 Adegnika AA, de Vries SG, Zinsou FJ, Honkepehedji YJ, Dejon Agobé JC, Vodonou KG, Bikangui R, Bouyoukou Hounkpatin A, Bache EB, Massinga Loembe M, van Leeuwen R, Molemans M, Kremsner PG, Yazdanbakhsh M, Hotez PJ, et al. Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial. The Lancet. Infectious Diseases. PMID 32926834 DOI: 10.1016/S1473-3099(20)30288-7  0.392
2020 Mejia R, Hotez P, Bottazzi ME. Global COVID-19 Efforts as the Platform to Achieving the Sustainable Development Goals. Current Tropical Medicine Reports. 1-5. PMID 32844081 DOI: 10.1007/S40475-020-00209-Y  0.316
2020 Ness TE, Agrawal V, Bedard K, Ouellette L, Erickson TA, Hotez P, Weatherhead JE. Maternal Hookworm Infection and Its Effects on Maternal Health: A Systematic Review and Meta-Analysis. The American Journal of Tropical Medicine and Hygiene. PMID 32840198 DOI: 10.4269/Ajtmh.20-0503  0.306
2020 Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, ... ... Hotez P, et al. Correction: Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. Plos Neglected Tropical Diseases. 14: e0008670. PMID 32804987 DOI: 10.1371/Journal.Pntd.0008670  0.313
2020 Franco-Paredes C, Jankousky K, Schultz J, Bernfeld J, Cullen K, Quan NG, Kon S, Hotez P, Henao-Martínez AF, Krsak M. COVID-19 in jails and prisons: A neglected infection in a marginalized population. Plos Neglected Tropical Diseases. 14: e0008409. PMID 32569274 DOI: 10.1371/Journal.Pntd.0008409  0.348
2020 Versteeg L, Wei J, Liu Z, Keegan B, Fujiwara RT, Jones KM, Asojo O, Strych U, Bottazzi ME, Hotez PJ, Zhan B. Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. Plos Neglected Tropical Diseases. 14: e0008057. PMID 32053593 DOI: 10.1371/Journal.Pntd.0008057  0.387
2019 Gostin LO, Hodge JG, Bloom BR, El-Mohandes A, Fielding J, Hotez P, Kurth A, Larson HJ, Orenstein WA, Rabin K, Ratzan SC, Salmon D. The public health crisis of underimmunisation: a global plan of action. The Lancet. Infectious Diseases. PMID 31706795 DOI: 10.1016/S1473-3099(19)30558-4  0.352
2019 Versteeg L, Almutairi MM, Hotez PJ, Pollet J. Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections. Vaccines. 7. PMID 31547081 DOI: 10.3390/vaccines7040122  0.339
2019 P JG, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. Plos Neglected Tropical Diseases. 13: e0007730. PMID 31525197 DOI: 10.1371/Journal.Pntd.0007730  0.32
2019 Ratzan SC, Bloom BR, El-Mohandes A, Fielding J, Gostin LO, Hodge JG, Hotez P, Kurth A, Larson HJ, Nurse J, Omer SB, Orenstein WA, Salmon D, Rabin K. The Salzburg Statement on Vaccination Acceptance. Journal of Health Communication. 1-3. PMID 31262227 DOI: 10.1080/10810730.2019.1622611  0.33
2019 Barry MA, Versteeg L, Wang Q, Pollet J, Zhan B, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. Plos Neglected Tropical Diseases. 13: e0007413. PMID 31145733 DOI: 10.1371/journal.pntd.0007413  0.305
2019 Hotez P. The physician-scientist: defending vaccines and combating antiscience. The Journal of Clinical Investigation. 130. PMID 31033486 DOI: 10.1172/Jci129121  0.33
2019 Hotez P. America and Europe's new normal: the return of vaccine-preventable diseases. Pediatric Research. PMID 30812027 DOI: 10.1038/S41390-019-0354-3  0.335
2019 Zinsou JF, Honpkehedji J, Agobe Jean Claude D, Adegbite BR, Ronald Edoa J, Van Leeuwen R, Diemert D, Elena Botazzi M, Kremsner PG, Yazdanbakhsh M, Hotez P, P Grobusch M, Akim Adegnika A, De Vries S. OC 8521 PRELIMINARY REPORT ON SAFETY OF CO-ADMINISTERED HUMAN HOOKWORM VACCINE CANDIDATES NA-APR-1 (M74)/ALHYDROGEL® AND NA-GST-1/ALHYDROGEL® IN GABONESE CHILDREN Bmj Global Health. 4: A12.1-A12. DOI: 10.1136/Bmjgh-2019-Edc.28  0.343
2018 Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. Plos Neglected Tropical Diseases. 12: e0006772. PMID 30296268 DOI: 10.1371/Journal.Pntd.0006772  0.32
2018 Briggs N, Wei J, Versteeg L, Zhan B, Keegan B, Damania A, Pollet J, Hayes KS, Beaumier C, Seid CA, Leong J, Grencis RK, Bottazzi ME, Sastry KJ, Hotez PJ. Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. Plos Pathogens. 14: e1007273. PMID 30153307 DOI: 10.1371/journal.ppat.1007273  0.323
2018 Bouchery T, Filbey K, Shepherd A, Chandler J, Patel D, Schmidt A, Camberis M, Peignier A, Smith AAT, Johnston K, Painter G, Pearson M, Giacomin P, Loukas A, Bottazzi ME, ... Hotez P, et al. A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. Plos Pathogens. 14: e1006931. PMID 29566094 DOI: 10.1371/Journal.Ppat.1006931  0.391
2018 Villanueva-Lizama LE, Cruz-Chan JV, Aguilar-Cetina ADC, Herrera-Sanchez LF, Rodriguez-Perez JM, Rosado-Vallado ME, Ramirez-Sierra MJ, Ortega-Lopez J, Jones K, Hotez P, Bottazzi ME, Dumonteil E. Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. Plos Neglected Tropical Diseases. 12: e0006240. PMID 29377898 DOI: 10.1371/Journal.Pntd.0006240  0.335
2017 Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Onchocerca volvulus: The Road from Basic Biology to a Vaccine. Trends in Parasitology. PMID 28958602 DOI: 10.1016/J.Pt.2017.08.011  0.351
2017 Wei J, Versteeg L, Liu Z, Keegan B, Gazzinelli-Guimarães AC, Fujiwara RT, Briggs N, Jones KM, Strych U, Beaumier CM, Bottazzi ME, Hotez PJ, Zhan B. Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. Plos Neglected Tropical Diseases. 11: e0005769. PMID 28708895 DOI: 10.1371/journal.pntd.0005769  0.33
2017 Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, ... ... Hotez P, et al. Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. Plos Neglected Tropical Diseases. 11: e0005574. PMID 28464026 DOI: 10.1371/Journal.Pntd.0005574  0.313
2017 Asojo OA, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, Abdeladhim M, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, ... Hotez PJ, et al. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. Plos Neglected Tropical Diseases. 11: e0005374. PMID 28278244 DOI: 10.1371/Journal.Pntd.0005374  0.318
2017 Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine. Plos Neglected Tropical Diseases. 11: e0005385. PMID 28192438 DOI: 10.1371/Journal.Pntd.0005385  0.383
2017 Eppes C, Rac M, Dunn J, Versalovic J, Murray KO, Suter MA, Sanz Cortes M, Espinoza J, Seferovic MD, Lee W, Hotez P, Mastrobattista J, Clark SL, Belfort MA, Aagaard KM. Testing for Zika Virus (ZIKV) Infection in Pregnancy: Key Concepts to Deal with an Emerging Epidemic. American Journal of Obstetrics and Gynecology. PMID 28126366 DOI: 10.1016/J.Ajog.2017.01.020  0.356
2017 Adegnika A, Vries SD, Zinsou FJ, Honkpehedji J, Dejon JC, Loembe MM, Bache B, Pakker N, Leeuwen RV, Hounkpatin AB, Kremsner P, Yazdanbakhsh M, Lell B, Bethony J, Hotez P, et al. SAFETY AND IMMUNOGENICITY OF CO-ADMINISTERED HOOKWORM VACCINE CANDIDATES NA-GST-1 AND NA-APR-1 WITH ALHYDROGEL® AND GLUCOPYRANOSYL-LIPID A IN GABONESE ADULTS: INTERIM RESULTS Bmj Global Health. 2: A12.3-A13. DOI: 10.1136/Bmjgh-2016-000260.29  0.359
2016 Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Hookworm infection. Nature Reviews. Disease Primers. 2: 16088. PMID 27929101 DOI: 10.1038/nrdp.2016.88  0.322
2016 Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, et al. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine. 8: 362ra143. PMID 27797959 DOI: 10.1126/Scitranslmed.Aaf8807  0.331
2016 Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B. The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates. Parasites & Vectors. 9: 518. PMID 27677574 DOI: 10.1186/s13071-016-1795-8  0.394
2016 Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY. The Global Economic and Health Burden of Human Hookworm Infection. Plos Neglected Tropical Diseases. 10: e0004922. PMID 27607360 DOI: 10.1371/journal.pntd.0004922  0.322
2016 Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. PMID 27171753 DOI: 10.1016/J.Vaccine.2016.03.112  0.317
2016 Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. PMID 27040400 DOI: 10.1016/j.vaccine.2016.03.078  0.329
2016 Bartsch SM, Hotez PJ, Hertenstein DL, Diemert DJ, Zapf KM, Bottazzi ME, Bethony JM, Brown ST, Lee BY. Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting. Vaccine. PMID 27002501 DOI: 10.1016/J.Vaccine.2016.03.018  0.41
2015 Zhan B, Ajmera R, Geiger S, Gonçalves MT, Liu Z, Wei J, Wilkins PP, Fujiwara R, Gazzinelli-Guimaraes PH, Bottazzi ME, Hotez P. Identification of Immunodominant Antigens for the Laboratory Diagnosis of Toxocariasis. Tropical Medicine & International Health : Tm & Ih. PMID 26426162 DOI: 10.1111/Tmi.12607  0.384
2015 Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annual Review of Medicine. PMID 26356803 DOI: 10.1146/annurev-med-051214-024241  0.303
2015 Pearson MS, Jariwala AR, Abbenante G, Plieskatt J, Wilson D, Bottazzi ME, Hotez PJ, Keegan B, Bethony JM, Loukas A. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Human Vaccines & Immunotherapeutics. 11: 1251-7. PMID 26018444 DOI: 10.4161/21645515.2014.980199  0.338
2015 Seid CA, Curti E, Jones RM, Hudspeth E, Rezende W, Pollet J, Center L, Versteeg L, Pritchard S, Musiychuk K, Yusibov V, Hotez PJ, Bottazzi ME. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Human Vaccines & Immunotherapeutics. 11: 1474-88. PMID 25905574 DOI: 10.1080/21645515.2015.1036207  0.366
2015 Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. Plos Neglected Tropical Diseases. 9: e0003575. PMID 25880767 DOI: 10.1371/journal.pntd.0003575  0.31
2014 Hotez P. Tropical Medicine in the Horse Latitudes. Current Tropical Medicine Reports. 1: 3-5. PMID 32226713 DOI: 10.1007/S40475-013-0003-6  0.336
2014 Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Human Vaccines & Immunotherapeutics. 10: 1914-25. PMID 25424799 DOI: 10.4161/hv.28872  0.411
2014 Ndeffo Mbah ML, Skrip L, Greenhalgh S, Hotez P, Galvani AP. Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa. Plos Neglected Tropical Diseases. 8: e3234. PMID 25329403 DOI: 10.1371/Journal.Pntd.0003234  0.376
2014 Knight JM, Zingales B, Bottazzi ME, Hotez P, Zhan B. Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunology. 36: 708-12. PMID 25040249 DOI: 10.1111/Pim.12130  0.364
2014 Hotez P, Whitham M. Helminth infections: a new global women's health agenda. Obstetrics and Gynecology. 123: 155-60. PMID 24463676 DOI: 10.1097/Aog.0000000000000025  0.313
2014 Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, et al. Genome of the human hookworm Necator americanus. Nature Genetics. 46: 261-269. PMID 24441737 DOI: 10.1038/ng.2875  0.668
2014 Zhan B, Beaumier CM, Briggs N, Jones KM, Keegan BP, Bottazzi ME, Hotez PJ. Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Review of Vaccines. 13: 321-31. PMID 24392641 DOI: 10.1586/14760584.2014.872035  0.337
2013 Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, et al. The Human Hookworm Vaccine. Vaccine. 31: B227-32. PMID 23598487 DOI: 10.1016/J.Vaccine.2012.11.034  0.313
2012 Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Valerio MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. The Journal of Allergy and Clinical Immunology. 130: 13-21. PMID 22742835 DOI: 10.1016/J.Jaci.2012.05.029  0.37
2012 Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. The Journal of Allergy and Clinical Immunology. 130: 169-76.e6. PMID 22633322 DOI: 10.1016/J.Jaci.2012.04.027  0.364
2012 Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expression and Purification. 83: 145-51. PMID 22503665 DOI: 10.1016/j.pep.2012.03.013  0.375
2012 Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Human Vaccines & Immunotherapeutics. 8: 765-76. PMID 22495115 DOI: 10.4161/hv.19726  0.367
2012 Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, ... Hotez PJ, et al. Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine. Infection and Immunity. 80: 1606-14. PMID 22311924 DOI: 10.1128/Iai.06212-11  0.321
2012 Xue J, Zhan B, Guo J, He N, Qiang HQ, Hotez P, Xiao SH. Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Experimental Parasitology. 130: 6-12. PMID 22024448 DOI: 10.1016/J.Exppara.2011.10.007  0.397
2012 Hotez PJ, Gilman RH. Hookworm and Strongyloides Infections Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. 808-813. DOI: 10.1016/B978-1-4160-4390-4.00109-0  0.399
2011 Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine. 29: D104-10. PMID 22188933 DOI: 10.1016/J.Vaccine.2011.06.024  0.335
2011 Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. A history of hookworm vaccine development. Human Vaccines. 7: 1234-44. PMID 22064562 DOI: 10.4161/Hv.7.11.18443  0.371
2011 Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. Omics : a Journal of Integrative Biology. 15: 567-77. PMID 21679087 DOI: 10.1089/Omi.2010.0150  0.312
2011 Hotez P. A handful of 'antipoverty' vaccines exist for neglected diseases, but the world's poorest billion people need more. Health Affairs (Project Hope). 30: 1080-7. PMID 21653960 DOI: 10.1377/Hlthaff.2011.0317  0.39
2011 Alexander N, Cundill B, Sabatelli L, Bethony JM, Diemert D, Hotez P, Smith PG, Rodrigues LC, Brooker S. Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine. 29: 3686-94. PMID 21435404 DOI: 10.1016/J.Vaccine.2011.03.026  0.397
2011 Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P. Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 177: 42-8. PMID 21251931 DOI: 10.1016/J.Molbiopara.2011.01.008  0.326
2011 Hotez PJ. Hookworm Infections Tropical Infectious Diseases. 799-804. DOI: 10.1016/B978-0-7020-3935-5.00116-6  0.399
2010 Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A. Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Reviews. Microbiology. 8: 814-26. PMID 20948553 DOI: 10.1038/Nrmicro2438  0.346
2010 Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Review of Vaccines. 9: 1219-30. PMID 20923271 DOI: 10.1586/Erv.10.107  0.41
2010 Hotez P, Stillwaggon E, McDonald M, Todman L, DiGrazia L. National summit on neglected infections of poverty in the United States. Emerging Infectious Diseases. 16: e1. PMID 20409362 DOI: 10.3201/Eid1605.091863  0.407
2010 Pearson MS, Pickering DA, Tribolet L, Cooper L, Mulvenna J, Oliveira LM, Bethony JM, Hotez PJ, Loukas A. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. The Journal of Infectious Diseases. 201: 1561-9. PMID 20367477 DOI: 10.1086/651953  0.378
2010 Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, ... ... Hotez P, et al. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infection and Immunity. 78: 1552-63. PMID 20145100 DOI: 10.1128/Iai.00848-09  0.388
2010 Asojo OA, Goud GN, Zhan B, Ordonez K, Sedlacek M, Homma K, Deumic V, Gupta R, Brelsford J, Price MK, Ngamelue MN, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 172-6. PMID 20124715 DOI: 10.1107/S1744309109051616  0.373
2010 Basavaraju SV, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Corrigendum to “Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: Gene transcription pattern, ligand binding properties and structural characterization” [Mol. Biochem. Parasitol. 126 (1) (2003) 63–71] Molecular and Biochemical Parasitology. 173: 175. DOI: 10.1016/J.Molbiopara.2010.06.001  0.645
2009 Hotez P. Neglected diseases amid wealth in the United States and Europe. Health Affairs (Project Hope). 28: 1720-5. PMID 19887412 DOI: 10.1377/Hlthaff.28.6.1720  0.335
2009 Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P. New vaccines for developing countries: will it be feast or famine? American Journal of Law & Medicine. 35: 311-22. PMID 19697751 DOI: 10.1177/009885880903500204  0.38
2009 Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. The Journal of Infectious Diseases. 199: 904-12. PMID 19434933 DOI: 10.1086/597048  0.344
2009 Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, ... ... Hotez PJ, et al. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3007-19. PMID 19380510 DOI: 10.1096/Fj.09-131433  0.319
2008 Brooker S, Hotez PJ, Bundy DA. Hookworm-related anaemia among pregnant women: a systematic review. Plos Neglected Tropical Diseases. 2: e291. PMID 18820740 DOI: 10.1371/journal.pntd.0000291  0.278
2008 Zhan B, Gupta R, Wong SP, Bier S, Jiang D, Goud G, Hotez P. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 162: 142-8. PMID 18804124 DOI: 10.1016/J.Molbiopara.2008.08.008  0.394
2008 Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines. 7: 745-52. PMID 18665774 DOI: 10.1586/14760584.7.6.745  0.371
2008 Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Molecular and Biochemical Parasitology. 160: 90-9. PMID 18501979 DOI: 10.1016/j.molbiopara.2008.04.008  0.359
2008 Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 26: 2408-17. PMID 18396361 DOI: 10.1016/J.Vaccine.2008.02.049  0.381
2008 Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. The Journal of Clinical Investigation. 118: 1311-21. PMID 18382743 DOI: 10.1172/Jci34261  0.316
2008 Sabatelli L, Ghani AC, Rodrigues LC, Hotez PJ, Brooker S. Modelling heterogeneity and the impact of chemotherapy and vaccination against human hookworm. Journal of the Royal Society, Interface / the Royal Society. 5: 1329-41. PMID 18331978 DOI: 10.1098/rsif.2007.1255  0.409
2008 Diemert DJ, Bethony JM, Hotez PJ. Hookworm vaccines. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 46: 282-8. PMID 18171264 DOI: 10.1086/524070  0.367
2008 Mendez S, D' Samuel A, Antoine AD, Ahn S, Hotez P. Use of the air pouch model to investigate immune responses to a hookworm vaccine containing the Na-ASP-2 protein in rats. Parasite Immunology. 30: 53-6. PMID 18086017 DOI: 10.1111/J.1365-3024.2007.00994.X  0.367
2008 Hotez P. Hookworm and poverty. Annals of the New York Academy of Sciences. 1136: 38-44. PMID 17954674 DOI: 10.1196/Annals.1425.000  0.392
2008 Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Experimental Parasitology. 118: 32-40. PMID 17645877 DOI: 10.1016/J.Exppara.2007.05.010  0.435
2007 Hotez P. A new voice for the poor. Plos Neglected Tropical Diseases. 1: e77. PMID 17989790 DOI: 10.1371/Journal.Pntd.0000077  0.308
2007 Inan M, Fanders SA, Zhang W, Hotez PJ, Zhan B, Meagher MM. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods in Molecular Biology (Clifton, N.J.). 389: 65-76. PMID 17951635 DOI: 10.1007/978-1-59745-456-8_5  0.405
2007 Asojo OA, Homma K, Sedlacek M, Ngamelue M, Goud GN, Zhan B, Deumic V, Asojo O, Hotez PJ. X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. Bmc Structural Biology. 7: 42. PMID 17594497 DOI: 10.1186/1472-6807-7-42  0.365
2007 Feng J, Zhan B, Liu Y, Liu S, Williamson A, Goud G, Loukas A, Hotez P. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Molecular and Biochemical Parasitology. 152: 132-8. PMID 17280728 DOI: 10.1016/J.Molbiopara.2007.01.001  0.339
2007 Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clinical and Vaccine Immunology : Cvi. 14: 281-7. PMID 17267592 DOI: 10.1128/Cvi.00404-06  0.487
2007 Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, Hotez PJ, Correa-Oliveira R, Rodrigues LC, Bethony JM. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene. 101: 146-54. PMID 17027054 DOI: 10.1016/J.Trstmh.2006.05.012  0.318
2007 Patel J, Hotez P, Dharajiya N, Sur S. Hookworm Protein Necator Americanus-Ancyclostoma Secreted Protein 2 (Na-Asp-2) Inhibits Allergic Airway Inflammation Journal of Allergy and Clinical Immunology. 119: S133. DOI: 10.1016/j.jaci.2006.11.649  0.271
2006 Jian X, Jun-Min Y, Hai-Chou X, Hui-Qing Q, Hai-Nan R, Hotez P, Bin Z, Shu-Hua X. Protective immunity elicited by ultraviolet-irradiated third-stage infective hookworm (Necator americanus and Ancylostoma caninum) larvae in mice and hamsters. The Southeast Asian Journal of Tropical Medicine and Public Health. 37: 885-95. PMID 17333729  0.366
2006 Bethony JM, Loukas A, Hotez PJ, Knox DP. Vaccines against blood-feeding nematodes of humans and livestock. Parasitology. 133: S63-79. PMID 17274849 DOI: 10.1017/S0031182006001818  0.331
2006 Brooker S, Clements AC, Hotez PJ, Hay SI, Tatem AJ, Bundy DA, Snow RW. The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren. Malaria Journal. 5: 99. PMID 17083720 DOI: 10.1186/1475-2875-5-99  0.396
2006 Loukas A, Bethony J, Brooker S, Hotez P. Hookworm vaccines: past, present, and future. The Lancet. Infectious Diseases. 6: 733-41. PMID 17067922 DOI: 10.1016/S1473-3099(06)70630-2  0.449
2006 Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A. New technologies for the control of human hookworm infection. Trends in Parasitology. 22: 327-31. PMID 16709466 DOI: 10.1016/J.Pt.2006.05.004  0.36
2006 Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, Hotez PJ. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 367: 1521-32. PMID 16679166 DOI: 10.1016/S0140-6736(06)68653-4  0.342
2006 Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A. Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infection and Immunity. 74: 961-7. PMID 16428741 DOI: 10.1128/Iai.74.2.961-967.2006  0.397
2006 Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. The Journal of Infectious Diseases. 193: 155-62. PMID 16323144 DOI: 10.1086/498528  0.359
2005 Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S. Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Human Vaccines. 1: 123-8. PMID 17012856 DOI: 10.4161/Hv.1.3.1924  0.377
2005 Asojo OA, Loukas A, Inan M, Barent R, Huang J, Plantz B, Swanson A, Gouthro M, Meagher MM, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 391-4. PMID 16511050 DOI: 10.1107/S1744309105007748  0.31
2005 Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. Plos Medicine. 2: e295. PMID 16231975 DOI: 10.1371/Journal.Pmed.0020295  0.409
2005 Xue J, Hui-Qing Q, Jun-Ming Y, Fujiwara R, Zhan B, Hotez P, Shu-Hua X. Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Experimental Parasitology. 111: 219-23. PMID 16198341 DOI: 10.1016/J.Exppara.2005.08.002  0.363
2005 Zhan B, Liu S, Perally S, Xue J, Fujiwara R, Brophy P, Xiao S, Liu Y, Feng J, Williamson A, Wang Y, Bueno LL, Mendez S, Goud G, Bethony JM, ... ... Hotez PJ, et al. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infection and Immunity. 73: 6903-11. PMID 16177370 DOI: 10.1128/IAI.73.10.6903-6911.2005  0.731
2005 Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, ... ... Hotez PJ, et al. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 23: 4754-64. PMID 16054275 DOI: 10.1016/J.Vaccine.2005.04.040  0.401
2005 Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1743-5. PMID 16037096 DOI: 10.1096/Fj.05-3936Fje  0.366
2005 Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 23: 3123-30. PMID 15837211 DOI: 10.1016/J.Vaccine.2004.12.022  0.309
2005 Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hookworm: "the great infection of mankind". Plos Medicine. 2: e67. PMID 15783256 DOI: 10.1371/Journal.Pmed.0020067  0.413
2005 Asojo OA, Goud G, Dhar K, Loukas A, Zhan B, Deumic V, Liu S, Borgstahl GE, Hotez PJ. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. Journal of Molecular Biology. 346: 801-14. PMID 15713464 DOI: 10.1016/j.jmb.2004.12.023  0.366
2005 Brooker S, Bethony JM, Rodrigues LC, Alexander N, Geiger SM, Hotez PJ. Epidemiologic, immunologic and practical considerations in developing and evaluating a human hookworm vaccine Expert Review of Vaccines. 4: 35-50. DOI: 10.1586/14760584.4.1.35  0.403
2004 Brooker S, Bethony J, Hotez PJ. Human hookworm infection in the 21st century. Advances in Parasitology. 58: 197-288. PMID 15603764 DOI: 10.1016/S0065-308X(04)58004-1  0.333
2004 Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S. Hookworm infection. The New England Journal of Medicine. 351: 799-807. PMID 15317893 DOI: 10.1056/NEJMra032492  0.399
2004 Zhan B, Wang Y, Liu Y, Williamson A, Loukas A, Hawdon JM, Xue HC, Xiao SH, Hotez PJ. Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. International Journal For Parasitology. 34: 1037-45. PMID 15313130 DOI: 10.1016/j.ijpara.2004.04.015  0.704
2004 Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. A pore-forming haemolysin from the hookworm, Ancylostoma caninum. International Journal For Parasitology. 34: 1029-35. PMID 15313129 DOI: 10.1016/J.Ijpara.2004.04.013  0.301
2004 Hsieh GC, Loukas A, Wahl AM, Bhatia M, Wang Y, Williamson AL, Kehn KW, Maruyama H, Hotez PJ, Leitenberg D, Bethony J, Constant SL. A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 173: 2699-704. PMID 15294988 DOI: 10.4049/Jimmunol.173.4.2699  0.343
2004 Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. The Journal of Biological Chemistry. 279: 35950-7. PMID 15199048 DOI: 10.1074/Jbc.M405842200  0.352
2004 Loukas A, Bethony JM, Williamson AL, Goud GN, Mendez S, Zhan B, Hawdon JM, Elena Bottazzi M, Brindley PJ, Hotez PJ. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. The Journal of Infectious Diseases. 189: 1952-61. PMID 15122534 DOI: 10.1086/386346  0.715
2004 Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, ... ... Hotez PJ, et al. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. The Journal of Infectious Diseases. 189: 919-29. PMID 14976610 DOI: 10.1086/381901  0.715
2003 Jian X, Shu-Hua X, Hui-Qing Q, Sen L, Hotez P, Bing-Gui S, Hai-Chou X, Tie-Hua L, Bin Z. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans. Experimental Parasitology. 105: 192-200. PMID 14990312 DOI: 10.1016/J.Exppara.2003.12.016  0.418
2003 Hotez PJ, Ashcom J, Zhan B, Bethony J, Loukas A, Hawdon J, Wang Y, Jin Q, Jones KC, Dobardzic A, Dobardzic R, Bolden J, Essiet I, Brandt W, Russell PK, et al. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. The Journal of Parasitology. 89: 853-5. PMID 14533704 DOI: 10.1645/Ge-46R  0.729
2003 Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, et al. Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. International Journal For Parasitology. 33: 1245-58. PMID 13678639 DOI: 10.1016/s0020-7519(03)00158-9  0.75
2003 Jian X, Sen L, Hui-Qin Q, Hai-Nan R, Tie-Hua L, Hai-Chou X, Hotez PJ, Shu-Hua X. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Experimental Parasitology. 104: 62-6. PMID 12932761  0.315
2003 Zhan B, Liu Y, Badamchian M, Williamson A, Feng J, Loukas A, Hawdon JM, Hotez PJ. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. International Journal For Parasitology. 33: 897-907. PMID 12906874 DOI: 10.1016/s0020-7519(03)00111-5  0.683
2003 Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. International Journal For Parasitology. 33: 621-40. PMID 12782060 DOI: 10.1016/S0020-7519(03)00057-2  0.314
2003 Basavaraju SV, Basavaraju S, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Molecular and Biochemical Parasitology. 126: 63-71. PMID 12554085 DOI: 10.1016/S0166-6851(02)00253-0  0.685
2003 Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. The Journal of Infectious Diseases. 187: 484-94. PMID 12552433 DOI: 10.1086/367708  0.339
2002 Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 1336-44. PMID 12439796 DOI: 10.1086/344268  0.688
2002 Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1458-60. PMID 12205047 DOI: 10.1096/Fj.02-0181Fje  0.328
2002 Hotez PJ, Ashcom J, Bin Z, Bethony J, Williamson A, Hawdon JM, Jianjun F, Dobardzic A, Rizo I, Bolden J, Jin Q, Yan W, Dobardzic R, Chung-Debose S, Crowell M, et al. Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. The Journal of Parasitology. 88: 684-90. PMID 12197114 DOI: 10.1645/0022-3395(2002)088[0684:EOVWRF]2.0.CO;2  0.722
2002 Zhan B, Badamchian M, Meihua B, Ashcom J, Feng J, Hawdon J, Shuhua X, Hotez PJ. Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. The American Journal of Tropical Medicine and Hygiene. 66: 238-44. PMID 12139214 DOI: 10.4269/Ajtmh.2002.66.238  0.683
2002 Zhan B, Hotez PJ, Wang Y, Hawdon JM. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Molecular and Biochemical Parasitology. 120: 291-6. PMID 11897134 DOI: 10.1016/s0166-6851(01)00453-4  0.692
2002 Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Molecular and Biochemical Parasitology. 119: 107-16. PMID 11755191 DOI: 10.1016/S0166-6851(01)00409-1  0.35
2002 Hotez PJ, Bin Z, Bethony J, Jin Q, Hawdon JM, Young HA, Simmens S, Hitzelberg R, Zook BC. Natural History of Primary Canine Hookworm Infections After Three Different Oral Doses of Third-Stage Infective Larvae of Ancylostoma caninum Comparative Parasitology. 69: 72-80. DOI: 10.1654/1525-2647(2002)069[0072:NHOPCH]2.0.CO;2  0.706
2002 Hotez PJ. China's Hookworms The China Quarterly. 172: 1029-1041. DOI: 10.1017/S0009443902000608  0.359
2001 Shuhua X, Hotez PJ, Binggui S, Sen L, Huiqing Q, Haichou X, Bin Z, Zheng F. Electron and light microscopy of neutrophil responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Parasitology International. 50: 241-8. PMID 11719110  0.366
2001 Gandhi NS, Jizhang C, Khoshnood K, Fuying X, Shanwen L, Yaoruo L, Bin Z, Haechou X, Chongjin T, Yan W, Wensen W, Dungxing H, Chong C, Shuhua X, Hawdon JM, ... Hotez PJ, et al. Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. The Journal of Parasitology. 87: 739-43. PMID 11534635 DOI: 10.1645/0022-3395(2001)087[0739:Eonahi]2.0.Co;2  0.705
2000 Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Xiao SH, Li TH, Feng Z, Hotez P. Construction and analysis of cDNA library of Necator americanus third stage larvae. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 18: 26-8. PMID 12567467  0.641
2000 Lili Z, Bingxiang Z, Hong T, Shuhua X, Hotez P, Bing Z, Yangzhong L, Ying L, Haichou X, Hawdon J, Hui Y, Huizhen W, Zhen F. Epidemiology of human geohelminth infections (ascariasis, trichuriasis and necatoriasis) in Lushui and Puer Counties, Yunnan Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 448-53. PMID 11288999  0.718
2000 Qiang S, Bin Z, Shu-hua X, Zheng F, Hotez P, Hawdon JM. Variation between ASP-1 molecules from Ancylostoma caninum in China and the United States. The Journal of Parasitology. 86: 181-5. PMID 10701589 DOI: 10.1645/0022-3395(2000)086[0181:Vbamfa]2.0.Co;2  0.727
2000 Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G. A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proceedings of the National Academy of Sciences of the United States of America. 97: 460-5. PMID 10618440 DOI: 10.1073/Pnas.97.1.460  0.675
2000 Sen L, Ghosh K, Bin Z, Qiang S, Thompson MG, Hawdon JM, Koski RA, Shuhua X, Hotez PJ. Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 18: 1096-102. PMID 10590331 DOI: 10.1016/S0264-410X(99)00371-0  0.721
2000 Hotez PJ. Pediatric geohelminth infections: Trichuriasis, ascariasis, and hookworm infections Seminars in Pediatric Infectious Diseases. 11: 236-244. DOI: 10.1053/spid.2000.9637  0.398
2000 Hotez P. The other intestinal protozoa: Enteric infections caused by Blastocystis hominis, Entamoeba coli, and Dientamoeba fragilis Seminars in Pediatric Infectious Diseases. 11: 178-181. DOI: 10.1053/Pi.2000.6228  0.356
1999 Li T, Zhan B, Hawdon JM, Gong X, Xiao S, Shan Q, Feng Z, Hotez PJ. [Sequencing of cytochrome C oxidase 1 gene of Ancylostoma duodenale and Necator americanus]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 17: 81-3. PMID 12563786  0.634
1999 Yang Y, Xiao S, Ren H, Wu J, Feng Z, Hotez PJ. Cutaneous and subcutaneous mast cell and eosinophil responses after challenge in mice vaccinated with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1020-3. PMID 11721464  0.418
1999 Xiao S, Ren H, Yang Y, Liu S, Qiang H, Xue H, Feng Z, Hotez PJ. Length of protection by murine vaccination with living infective third-stage hookworm larvae. Chinese Medical Journal. 112: 1129-32. PMID 11721454  0.425
1999 Xue H, Liu S, Ren H, Qiang H, Xiao S, Feng Z, Hotez P. Enzyme-linked immunoelectrotransfer blotting analysis of human serologic responses to infective hookworm larval antigen. Chinese Medical Journal. 112: 249-50. PMID 11593560  0.396
1999 Yong W, Guangjin S, Weitu W, Shuhua X, Hotez PJ, Qiyang L, Haichou X, Xiaomei Y, Xiaoming L, Bin Z, Hawdon JM, Li C, Hong J, Chunmei H, Zheng F. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. The Southeast Asian Journal of Tropical Medicine and Public Health. 30: 692-7. PMID 10928362  0.727
1999 Yuanqing Y, Shuhua X, Hotez PJ, Jiadong W. Histochemical alterations of infective third-stage hookworm larvae (L3) in vaccinated mice. The Southeast Asian Journal of Tropical Medicine and Public Health. 30: 356-64. PMID 10774709  0.369
1999 Hotez PJ, Ghosh K, Hawdon JM, Narasimhan S, Jones B, Shuhua X, Sen L, Bin Z, Haechou X, Hainan R, Heng W, Koski RA. Experimental approaches to the development of a recombinant hookworm vaccine. Immunological Reviews. 171: 163-71. PMID 10582170 DOI: 10.1111/j.1600-065X.1999.tb01347.x  0.775
1999 Changhua L, Xiaorong Z, Dongchuan Q, Shuhua X, Hotez PJ, Defu Z, Hulian Z, Mingden L, Hainan R, Bing Z, Haichou X, Hawdon J, Zheng F. Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China. Acta Tropica. 73: 243-9. PMID 10546842 DOI: 10.1016/S0001-706X(99)00035-2  0.74
1999 Ghosh K, Hotez PJ. Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1. The Journal of Infectious Diseases. 180: 1674-81. PMID 10515831 DOI: 10.1086/315059  0.42
1999 Labiano-Abello N, Canese J, Velazquez ME, Hawdon JM, Wilson ML, Hotez PJ. Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study. Memã³Rias Do Instituto Oswaldo Cruz. 94: 583-6. PMID 10464397 DOI: 10.1590/S0074-02761999000500003  0.733
1999 Hawdon JM, Narasimhan S, Hotez PJ. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Molecular and Biochemical Parasitology. 99: 149-65. PMID 10340481 DOI: 10.1016/S0166-6851(99)00011-0  0.721
1999 Bin Z, Hawdon J, Qiang S, Hainan R, Huiqing Q, Wei H, Shu-Hua X, Tiehua L, Xing G, Zheng F, Hotez P. Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Molecular and Biochemical Parasitology. 98: 143-9. PMID 10029316 DOI: 10.1016/S0166-6851(98)00157-1  0.702
1998 Fenghua S, Zhongxing W, Yixing Q, Hangqun C, Haichou X, Hainan R, Shuhua X, Bin Z, Hawdon JM, Zheng F, Hotez PJ. Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. The Southeast Asian Journal of Tropical Medicine and Public Health. 29: 605-10. PMID 10437966  0.728
1998 Xiao S, Ren H, Yang Y, Xue H, Qiang H, Liu S, Feng Z, Hotez PJ. Protective immunity in mice elicited by living infective third-stage hookworm larvae (Shanghai strain of Ancylostoma caninum). Chinese Medical Journal. 111: 43-8. PMID 10322652  0.372
1998 Shuhua X, Hotez PJ, Binggui S, Sen L, Hainan R, Haichou X, Huiqing Q, Zheng F. Electron and light microscopy of peritoneal cellular immune responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Tropica. 71: 155-67. PMID 9821464  0.311
1998 Yang Y, Xiau S, Ren H, Wu J, Hotez PJ. Cutaneous and subcutaneous granulomata formation in mice immunized and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Tropica. 69: 229-38. PMID 9638275  0.324
1998 Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Gong X, Xiao S, Hotez P. Screening and sequential comparison of Ancylostoma-secreted protein 1 and 2 (ASP1, ASP2) genes from different species of hookworm Parasitology International. 47: 213. DOI: 10.1016/S1383-5769(98)80563-1  0.368
1997 Hotez PJ, Ghosh K, Hawdon J, Narasimhan S, Jones B, Bethony J. Vaccines for hookworm infection. The Pediatric Infectious Disease Journal. 16: 935-40. PMID 9380467 DOI: 10.1097/00006454-199710000-00006  0.747
1996 Ghosh K, Hawdon J, Hotez P. Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae. The Journal of Infectious Diseases. 174: 1380-3. PMID 8940240 DOI: 10.1093/Infdis/174.6.1380  0.764
1996 Hawdon JM, Hotez PJ. Hookworm: developmental biology of the infectious process. Current Opinion in Genetics & Development. 6: 618-23. PMID 8939719 DOI: 10.1016/S0959-437X(96)80092-X  0.725
1996 Hotez PJ, Hawdon JM, Cappello M, Jones BF, Ghosh K, Volvovitz F, Xiao SH. Molecular approaches to vaccinating against hookworm disease. Pediatric Research. 40: 515-21. PMID 8888276 DOI: 10.1203/00006450-199610000-00001  0.745
1996 Cappello M, Hawdon JM, Jones BF, Kennedy WP, Hotez PJ. Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli. Molecular and Biochemical Parasitology. 80: 113-7. PMID 8885227 DOI: 10.1016/0166-6851(96)02658-8  0.675
1996 Stanssens P, Bergum PW, Gansemans Y, Jespers L, Laroche Y, Huang S, Maki S, Messens J, Lauwereys M, Cappello M, Hotez PJ, Lasters I, Vlasuk GP. Anticoagulant repertoire of the hookworm Ancylostoma caninum Proceedings of the National Academy of Sciences of the United States of America. 93: 2149-2154. PMID 8700900 DOI: 10.1073/pnas.93.5.2149  0.333
1996 Hawdon JM, Jones BF, Hoffman DR, Hotez PJ. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. The Journal of Biological Chemistry. 271: 6672-8. PMID 8636085 DOI: 10.1074/Jbc.271.12.6672  0.734
1996 HOFFMAN D, HAWDON J, JONES B, HOTEZ P. 126 Helminth secretory proteins are related to wasp antigen 5 by both sequence and immunologic cross-reactivity Journal of Allergy and Clinical Immunology. 97: 214-214. DOI: 10.1016/S0091-6749(96)80344-7  0.668
1995 Hawdon JM, Jones BF, Perregaux MA, Hotez PJ. Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro. Experimental Parasitology. 80: 205-11. PMID 7895832 DOI: 10.1006/Expr.1995.1025  0.704
1995 Hawdon JM, Jones BF, Hotez PJ. Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae. Molecular and Biochemical Parasitology. 69: 127-30. PMID 7723782 DOI: 10.1016/0166-6851(94)00203-Y  0.699
1995 Hotez PJ, Hawdon JM, Cappello M, Jones BF, Pritchard DI. Molecular pathobiology of hookworm infection. Infectious Agents and Disease. 4: 71-5. PMID 7613730  0.732
1995 Cappello M, Vlasuk GP, Bergum PW, Huang S, Hotez PJ. Ancylostoma caninum anticoagulant peptide: A hookworm-derived inhibitor of human coagulation factor Xa Proceedings of the National Academy of Sciences of the United States of America. 92: 6152-6156. PMID 7597095 DOI: 10.1073/pnas.92.13.6152  0.313
1994 Hotez P, Cappello M, Hawdon J, Beckers C, Sakanari J. Hyaluronidases of the gastrointestinal invasive nematodes Ancylostoma caninum and Anisakis simplex: Possible functions in the pathogenesis of human zoonoses Journal of Infectious Diseases. 170: 918-926. PMID 7930737 DOI: 10.1093/Infdis/170.4.918  0.69
1993 Hotez P, Hawdon J, Schad GA. Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans Daf-c paradigm. Parasitology Today (Personal Ed.). 9: 23-6. PMID 15463660 DOI: 10.1016/0169-4758(93)90159-D  0.785
1993 Cappello M, Clyne LP, McPhedran P, Hotez PJ. Ancylostoma Factor Xa Inhibitor: Partial Purification and Its Identification as a Major Hookworm-Derived Anticoagulant In Vitro Journal of Infectious Diseases. 167: 1474-1477. PMID 8501344 DOI: 10.1093/infdis/167.6.1474  0.267
1992 Hotez PJ, Narasimhan S, Haggerty J, Milstone L, Bhopale V, Schad GA, Richards FF. Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans. Infection and Immunity. 60: 1018-23. PMID 1541516 DOI: 10.1128/Iai.60.3.1018-1023.1992  0.608
1990 Hotez P, Haggerty J, Hawdon J, Milstone L, Gamble HR, Schad G, Richards F. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis Infection and Immunity. 58: 3883-3892. PMID 2254016 DOI: 10.1128/Iai.58.12.3883-3892.1990  0.773
1990 Hotez P, Haggerty J, Hawdon J, Milstone L, Gamble HR, Schad G, Richards F. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis. Infection and Immunity. 58: 3883-3892. DOI: 10.1128/iai.58.12.3883-3892.1990  0.766
1987 Hotez PJ, Le Trang N, Cerami A. Hookworm antigens: the potential for vaccination. Parasitology Today (Personal Ed.). 3: 247-9. PMID 15462967 DOI: 10.1016/0169-4758(87)90148-7  0.613
1985 Cerami A, Ikeda Y, Le Trang N, Hotez PJ, Beutler B. Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor). Immunology Letters. 11: 173-7. PMID 3910566 DOI: 10.1016/0165-2478(85)90165-8  0.562
1985 Hotez PJ, Trang NL, McKerrow JH, Cerami A. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum. The Journal of Biological Chemistry. 260: 7343-8. PMID 3888998  0.517
1984 Hotez PJ, Le Trang N, Fairlamb AH, Cerami A. Lipoprotein lipase suppression in 3T3-L1 cells by a haematoprotozoan-induced mediator from peritoneal exudate cells. Parasite Immunology. 6: 203-9. PMID 6377200 DOI: 10.1111/J.1365-3024.1984.Tb00793.X  0.492
1983 Hotez PJ, Cerami A. Secretion of a proteolytic anticoagulant by Ancylostoma hookworms. The Journal of Experimental Medicine. 157: 1594-603. PMID 6343546 DOI: 10.1084/Jem.157.5.1594  0.478
Low-probability matches (unlikely to be authored by this person)
2015 Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. The Onchocerciasis Vaccine for Africa--TOVA--Initiative. Plos Neglected Tropical Diseases. 9: e0003422. PMID 25634641 DOI: 10.1371/Journal.Pntd.0003422  0.299
2018 Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ. Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen. Vaccine. PMID 29496347 DOI: 10.1016/J.Vaccine.2018.02.065  0.299
2020 Chen WH, Nyon MP, Poongavanam MV, Liu Z, Biter AB, Kundu RT, Strych U, Hotez PJ, Bottazzi ME. Process Characterization and Biophysical Analysis for a Yeast-expressed Phlebotomus papatasi Salivary Protein (PpSP15) as a Leishmania vaccine candidate. Journal of Pharmaceutical Sciences. PMID 32070701 DOI: 10.1016/j.xphs.2020.02.004  0.298
2020 Dumonteil E, Herrera C, Tu W, Goff K, Fahlberg M, Haupt E, Kaur A, Marx PA, Ortega-Lopez J, Hotez PJ, Bottazzi ME. Safety and immunogenicity of a recombinant vaccine against Trypanosoma cruzi in Rhesus macaques. Vaccine. PMID 32417142 DOI: 10.1016/J.Vaccine.2020.05.010  0.297
2023 Jones KM, Mangin EN, Reynolds CL, Villanueva LE, Cruz JV, Versteeg L, Keegan B, Kendricks A, Pollet J, Gusovsky F, Bottazzi ME, Hotez PJ. Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease. Frontiers in Cellular and Infection Microbiology. 13: 1106315. PMID 36844399 DOI: 10.3389/fcimb.2023.1106315  0.297
2011 Bethony JM, Cole RN, Guo X, Kamhawi S, Lightowlers MW, Loukas A, Petri W, Reed S, Valenzuela JG, Hotez PJ. Vaccines to combat the neglected tropical diseases. Immunological Reviews. 239: 237-70. PMID 21198676 DOI: 10.1111/J.1600-065X.2010.00976.X  0.296
2020 Haynes BF, Corey L, Fernandes P, Gilbert PB, Hotez PJ, Rao S, Santos MR, Schuitemaker H, Watson M, Arvin A. Prospects for a safe COVID-19 vaccine. Science Translational Medicine. PMID 33077678 DOI: 10.1126/scitranslmed.abe0948  0.296
2012 Zhan B, Santiago H, Keegan B, Gillespie P, Xue J, Bethony J, de Oliveira LM, Jiang D, Diemert D, Xiao SH, Jones K, Feng X, Hotez PJ, Bottazzi ME. Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE. Parasite Immunology. 34: 404-11. PMID 22651670 DOI: 10.1111/J.1365-3024.2012.01371.X  0.296
2016 Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. Plos Neglected Tropical Diseases. 10: e0004586. PMID 27045170 DOI: 10.1371/Journal.Pntd.0004586  0.295
2002 Shuhua X, Jiqing Y, Mingjie W, Pieying J, Fanghua G, Junjie C, Wei J, Hotez P. Augmented bioavailability and cysticidal activity of albendazole reformulated in soybean emulsion in mice infected with Echinococcus granulosus or Echinococcus multilocularis. Acta Tropica. 82: 77-84. PMID 11904106 DOI: 10.1016/S0001-706X(02)00027-X  0.294
2020 Hotez PJ. Toxocariasis: A neglected infection for the Anthropocene epoch. Advances in Parasitology. 109: 879-883. PMID 32381232 DOI: 10.1016/bs.apar.2020.03.004  0.293
2015 Martinez-Campos V, Martinez-Vega P, Ramirez-Sierra MJ, Rosado-Vallado M, Seid CA, Hudspeth EM, Wei J, Liu Z, Kwityn C, Hammond M, Ortega-López J, Zhan B, Hotez PJ, Bottazzi ME, Dumonteil E. Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice. Vaccine. PMID 26192358 DOI: 10.1016/j.vaccine.2015.07.017  0.29
2009 Hotez PJ, Brown AS. Neglected tropical disease vaccines. Biologicals : Journal of the International Association of Biological Standardization. 37: 160-4. PMID 19278869 DOI: 10.1016/j.biologicals.2009.02.008  0.289
2012 Pearson MS, Pickering DA, McSorley HJ, Bethony JM, Tribolet L, Dougall AM, Hotez PJ, Loukas A. Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. Plos Neglected Tropical Diseases. 6: e1564. PMID 22428079 DOI: 10.1371/Journal.Pntd.0001564  0.288
2009 Hotez PJ. Mass drug administration and integrated control for the world's high-prevalence neglected tropical diseases. Clinical Pharmacology and Therapeutics. 85: 659-64. PMID 19322166 DOI: 10.1038/Clpt.2009.16  0.288
2023 Clímaco MC, de Figueiredo LA, Lucas RC, Pinheiro GRG, Dias Magalhães LM, Oliveira ALG, Almeida RM, Barbosa FS, Castanheira Bartholomeu D, Bueno LL, Mendes TA, Zhan B, Jones KM, Hotez P, Bottazzi ME, et al. Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis. Vaccine. 41: 5400-5411. PMID 37479612 DOI: 10.1016/j.vaccine.2023.07.020  0.287
2014 Mejia R, Vargas P, Jeun R, Krolewiecki A, Juarez M, Cajal P, Nasser J, Hotez P, Cimino R. 1789Multi-parallel quantitative real-time PCR surveillance of gastrointestinal parasites in a symptomatic rural Argentinian population: initial results of the Latin American Multicenter Parasite Study (LAMPS) Open Forum Infectious Diseases. 1: S59-S59. DOI: 10.1093/Ofid/Ofu051.161  0.287
2006 Hotez P, Ottesen E, Fenwick A, Molyneux D. The neglected tropical diseases: the ancient afflictions of stigma and poverty and the prospects for their control and elimination. Advances in Experimental Medicine and Biology. 582: 23-33. PMID 16802616 DOI: 10.1007/0-387-33026-7_3  0.287
2000 Cowden J, Hotez P. Mebendazole and albendazole treatment of geohelminth infections in children and pregnant women. The Pediatric Infectious Disease Journal. 19: 659-60. PMID 10917227 DOI: 10.1097/00006454-200007000-00017  0.285
2013 Hotez PJ, Dumonteil E, Heffernan MJ, Bottazzi ME. Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas. Advances in Experimental Medicine and Biology. 764: 1-12. PMID 23654053 DOI: 10.1007/978-1-4614-4726-9_1  0.284
2023 Hotez PJ, Bottazzi ME. Human Schistosomiasis Vaccines as Next Generation Control Tools. Tropical Medicine and Infectious Disease. 8. PMID 36977171 DOI: 10.3390/tropicalmed8030170  0.284
2023 Hotez PJ. Vaccine Preventable Disease and Vaccine Hesitancy. The Medical Clinics of North America. 107: 979-987. PMID 37806729 DOI: 10.1016/j.mcna.2023.05.012  0.283
2020 Kendricks AL, Gray SB, Wilkerson GK, Sands CM, Abee CR, Bernacky BJ, Hotez PJ, Bottazzi ME, Craig SL, Jones KM. Reproductive Outcomes in Rhesus Macaques (Macaca mulatta) with Naturally-acquired Trypanosoma cruzi Infection. Comparative Medicine. PMID 32183928 DOI: 10.30802/AALAS-CM-19-000077  0.283
2007 Brooker S, Akhwale W, Pullan R, Estambale B, Clarke SE, Snow RW, Hotez PJ. Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. The American Journal of Tropical Medicine and Hygiene. 77: 88-98. PMID 18165479  0.283
2021 Rostami A, Sepidarkish M, Fazlzadeh A, Mokdad AH, Sattarnezhad A, Esfandyari S, Riahi SM, Mollalo A, Dooki ME, Bayani M, Nazemipour M, Mansournia MA, Hotez PJ, Gasser RB. Update on SARS-CoV-2 seroprevalence: regional and worldwide. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 27: 1762-1771. PMID 34582980 DOI: 10.1016/j.cmi.2021.09.019  0.282
1997 Hotez PJ, Zheng F, Long-qi X, Ming-gang C, Shu-hua X, Shu-xian L, Blair D, McManus DP, Davis GM. Emerging and reemerging helminthiases and the public health of China. Emerging Infectious Diseases. 3: 303-10. PMID 9284374 DOI: 10.3201/eid0303.970306  0.282
2021 Chen WH, Wei J, Kundu RT, Adhikari R, Liu Z, Lee J, Versteeg L, Poveda C, Keegan B, Villar MJ, de Araujo Leao AC, Rivera JA, Gillespie PM, Pollet J, Strych U, ... ... Hotez PJ, et al. Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate. Biochimica Et Biophysica Acta. General Subjects. 129893. PMID 33731300 DOI: 10.1016/j.bbagen.2021.129893  0.282
2022 Dzul-Huchim VM, Ramirez-Sierra MJ, Martinez-Vega PP, Rosado-Vallado ME, Arana-Argaez VE, Ortega-Lopez J, Gusovsky F, Dumonteil E, Cruz-Chan JV, Hotez P, Bottazzi ME, Villanueva-Lizama LE. Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice. Plos Neglected Tropical Diseases. 16: e0010258. PMID 36095001 DOI: 10.1371/journal.pntd.0010258  0.282
2018 de la Cruz JJ, Villanueva-Lizama L, Dzul-Huchim V, Ramírez-Sierra MJ, Martinez-Vega P, Rosado-Vallado M, Ortega-Lopez J, Flores-Pucheta CI, Gillespie P, Zhan B, Bottazzi ME, Hotez PJ, Dumonteil E. Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Human Vaccines & Immunotherapeutics. PMID 30192702 DOI: 10.1080/21645515.2018.1520581  0.282
2016 Briggs N, Weatherhead J, Sastry KJ, Hotez PJ. The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections. Plos Neglected Tropical Diseases. 10: e0004944. PMID 27632204 DOI: 10.1371/journal.pntd.0004944  0.278
2012 Lee BY, Bacon KM, Wateska AR, Bottazzi ME, Dumonteil E, Hotez PJ. Modeling the economic value of a Chagas' disease therapeutic vaccine. Human Vaccines & Immunotherapeutics. 8: 1293-301. PMID 22894964 DOI: 10.4161/hv.20966  0.277
2017 Bailey F, Mondragon-Shem K, Hotez P, Ruiz-Postigo JA, Al-Salem W, Acosta-Serrano Á, Molyneux DH. A new perspective on cutaneous leishmaniasis-Implications for global prevalence and burden of disease estimates. Plos Neglected Tropical Diseases. 11: e0005739. PMID 28796782 DOI: 10.1371/Journal.Pntd.0005739  0.275
2014 Hess JA, Zhan B, Bonne-Année S, Deckman JM, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. International Journal For Parasitology. 44: 637-46. PMID 24907553 DOI: 10.1016/J.Ijpara.2014.04.006  0.274
2020 Liu Z, Kundu R, Damena S, Biter AB, Nyon MP, Chen WH, Zhan B, Strych U, Hotez PJ, Bottazzi ME. A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis. Protein Expression and Purification. 105750. PMID 32920041 DOI: 10.1016/j.pep.2020.105750  0.273
2009 Stoever K, Molyneux D, Hotez P, Fenwick A. HIV/AIDS, schistosomiasis, and girls. Lancet. 373: 2025-6. PMID 19524778 DOI: 10.1016/S0140-6736(09)61111-9  0.273
2005 Mendez S, Valenzuela JG, Wu W, Hotez PJ. Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster. Infection and Immunity. 73: 3402-7. PMID 15908367 DOI: 10.1128/Iai.73.6.3402-3407.2005  0.273
2016 Merrifield M, Hotez PJ, Beaumier CM, Gillespie P, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent human schistosomiasis. Vaccine. PMID 27036511 DOI: 10.1016/j.vaccine.2016.03.079  0.273
2016 Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, ... Hotez PJ, et al. Cysteine Mutagenesis Improves the Production without Abrogating Antigenicity of a Recombinant Protein Vaccine Candidate for Human Chagas Disease. Human Vaccines & Immunotherapeutics. 0. PMID 27737611 DOI: 10.1080/21645515.2016.1242540  0.273
2011 Hotez PJ, Alibek K. Central Asia's hidden burden of neglected tropical diseases. Plos Neglected Tropical Diseases. 5: e1224. PMID 21980541 DOI: 10.1371/Journal.Pntd.0001224  0.271
2019 Bailey F, Mondragon-Shem K, Haines LR, Olabi A, Alorfi A, Ruiz-Postigo JA, Alvar J, Hotez P, Adams ER, Vélez ID, Al-Salem W, Eaton J, Acosta-Serrano Á, Molyneux DH. Cutaneous leishmaniasis and co-morbid major depressive disorder: A systematic review with burden estimates. Plos Neglected Tropical Diseases. 13: e0007092. PMID 30802261 DOI: 10.1371/Journal.Pntd.0007092  0.271
2019 Hoffman KA, Reynolds C, Bottazzi ME, Hotez P, Jones K. Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. Journal of the American Heart Association. 8: e013365. PMID 31718442 DOI: 10.1161/Jaha.119.013365  0.27
2023 Shoham S, Batista C, Ben Amor Y, Ergonul O, Hassanain M, Hotez P, Kang G, Kim JH, Lall B, Larson HJ, Naniche D, Sheahan T, Strub-Wourgaft N, Sow SO, Wilder-Smith A, et al. Vaccines and therapeutics for immunocompromised patients with COVID-19. Eclinicalmedicine. 59: 101965. PMID 37070102 DOI: 10.1016/j.eclinm.2023.101965  0.269
2017 Konduri V, Halpert MM, Liang D, Levitt JM, Cruz JVC, Zhan B, Bottazzi ME, Hotez PJ, Jones KM, Decker WK. Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy. Infection and Immunity. PMID 28674032 DOI: 10.1128/IAI.00127-17  0.269
2006 Hotez PJ, Ferris MT. The antipoverty vaccines. Vaccine. 24: 5787-99. PMID 16759763 DOI: 10.1016/j.vaccine.2006.05.008  0.268
2006 Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM. Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine. 24: 501-9. PMID 16140437 DOI: 10.1016/J.Vaccine.2005.07.091  0.268
2023 Poveda C, Leão AC, Mancino C, Taraballi F, Chen YL, Adhikari R, Villar MJ, Kundu R, Nguyen DM, Versteeg L, Strych U, Hotez PJ, Bottazzi ME, Pollet J, Jones KM. Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against , characterized by an increased level of polyfunctional CD8 T-cells. Current Research in Immunology. 4: 100066. PMID 37534309 DOI: 10.1016/j.crimmu.2023.100066  0.266
2015 Gunter SM, Jones KM, Zhan B, Essigmann HT, Murray KO, Garcia MN, Gorchakov R, Bottazzi ME, Hotez PJ, Brown EL. Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24. The American Journal of Tropical Medicine and Hygiene. PMID 26598565 DOI: 10.4269/Ajtmh.15-0438  0.266
2010 Hotez P. A national school of tropical medicine and neglected infections of poverty for North America. Plos Neglected Tropical Diseases. 4: e735. PMID 20614018 DOI: 10.1371/Journal.Pntd.0000735  0.266
2016 Gillespie PM, Beaumier CM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for leishmaniasis. Vaccine. PMID 26973063 DOI: 10.1016/j.vaccine.2015.12.071  0.266
2012 Dumonteil E, Bottazzi ME, Zhan B, Heffernan MJ, Jones K, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Lee BY, Bacon KM, Fleischer B, Slingsby BT, Cravioto MB, Tapia-Conyer R, ... Hotez PJ, et al. Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Review of Vaccines. 11: 1043-55. PMID 23151163 DOI: 10.1586/Erv.12.85  0.266
2013 Curti E, Kwityn C, Zhan B, Gillespie P, Brelsford J, Deumic V, Plieskatt J, Rezende WC, Tsao E, Kalampanayil B, Hotez PJ, Bottazzi ME. Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Human Vaccines & Immunotherapeutics. 9: 2342-50. PMID 23899507 DOI: 10.4161/hv.25787  0.265
2018 Diemert DJ, Bottazzi ME, Plieskatt J, Hotez PJ, Bethony JM. Lessons along the Critical Path: Developing Vaccines against Human Helminths. Trends in Parasitology. PMID 30064902 DOI: 10.1016/J.Pt.2018.07.005  0.264
2018 Diemert DJ, Bottazzi ME, Plieskatt J, Hotez PJ, Bethony JM. Lessons along the Critical Path: Developing Vaccines against Human Helminths. Trends in Parasitology. PMID 30064902 DOI: 10.1016/j.pt.2018.07.005  0.264
2013 Cheng W, Curti E, Rezende WC, Kwityn C, Zhan B, Gillespie P, Plieskatt J, Joshi SB, Volkin DB, Hotez PJ, Middaugh CR, Bottazzi ME. Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Human Vaccines & Immunotherapeutics. 9: 2351-61. PMID 23880663 DOI: 10.4161/Hv.25788  0.264
2022 Chen WH, Pollet J, Strych U, Lee J, Liu Z, Kundu RT, Versteeg L, Villar MJ, Adhikari R, Wei J, Poveda C, Keegan B, Bailey AO, Chen YL, Gillespie PM, ... ... Hotez PJ, et al. Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate. Protein Expression and Purification. 190: 106003. PMID 34688919 DOI: 10.1016/j.pep.2021.106003  0.264
2022 González-López C, Chen WH, Alfaro-Chacón A, Villanueva-Lizama LE, Rosado-Vallado M, Ramirez-Sierra MJ, Teh-Poot CF, Pollet J, Asojo O, Jones KM, Hotez PJ, Elena Bottazzi M, Cruz-Chan JV. A novel multi-epitope recombinant protein elicits an antigen-specific CD8+ T cells response in Trypanosoma cruzi-infected mice. Vaccine. 40: 6445-6449. PMID 36184402 DOI: 10.1016/j.vaccine.2022.09.068  0.263
2019 Hotez PJ. Immunizations and vaccines: a decade of successes and reversals, and a call for 'vaccine diplomacy'. International Health. PMID 31034023 DOI: 10.1093/inthealth/ihz024  0.262
2020 Pollet J, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Mondragon MV, de Araujo Leao AC, Rivera JA, Gillespie PM, ... ... Hotez PJ, et al. SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice. Biorxiv : the Preprint Server For Biology. PMID 33173864 DOI: 10.1101/2020.11.04.367359  0.262
2021 Pollet J, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, de Araujo Leao AC, Altieri Rivera J, Momin Z, ... ... Hotez PJ, et al. SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice. Human Vaccines & Immunotherapeutics. 1-11. PMID 33847226 DOI: 10.1080/21645515.2021.1901545  0.262
2013 Barry MA, Weatherhead JE, Hotez PJ, Woc-Colburn L. Childhood parasitic infections endemic to the United States. Pediatric Clinics of North America. 60: 471-85. PMID 23481112 DOI: 10.1016/j.pcl.2012.12.011  0.26
2015 Anderson JP, Rascoe LN, Levert K, Chastain HM, Reed MS, Rivera HN, McAuliffe I, Zhan B, Wiegand RE, Hotez PJ, Wilkins PP, Pohl J, Handali S. Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26. Plos Neglected Tropical Diseases. 9: e0004168. PMID 26485145 DOI: 10.1371/journal.pntd.0004168  0.26
2021 Hotez P. Preventing the next pandemic and tackling antiscience: an interview with Peter Hotez. Future Microbiology. 16: 539-541. PMID 33998265 DOI: 10.2217/fmb-2021-0088  0.26
2009 Hotez PJ, Kamath A. Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden. Plos Neglected Tropical Diseases. 3: e412. PMID 19707588 DOI: 10.1371/journal.pntd.0000412  0.259
2018 Jones K, Versteeg L, Damania A, Keegan B, Kendricks A, Pollet J, Cruz-Chan JV, Gusovsky F, Hotez PJ, Bottazzi ME. Vaccine-linked chemotherapy improves benznidazole efficacy for acute Chagas disease. Infection and Immunity. PMID 29311242 DOI: 10.1128/IAI.00876-17  0.259
2020 Hotez PJ, Bottazzi ME, Corry DB. The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement. Microbes and Infection. PMID 32305501 DOI: 10.1016/j.micinf.2020.04.005  0.259
2012 Hotez PJ, Bethony JM. Parasitic disease vaccines Vaccines: Sixth Edition. 1154-1160. DOI: 10.1016/B978-1-4557-0090-5.00059-8  0.258
2010 Hotez PJ. Neglected infections of poverty among the indigenous peoples of the arctic. Plos Neglected Tropical Diseases. 4: e606. PMID 20126272 DOI: 10.1371/journal.pntd.0000606  0.258
2013 Hotez P, Singh SK, Zhou XN. Advancing Sino-Indian cooperation to combat tropical diseases. Plos Neglected Tropical Diseases. 7: e2204. PMID 24086775 DOI: 10.1371/Journal.Pntd.0002204  0.255
2009 Hotez PJ, Wilkins PP. Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance? Plos Neglected Tropical Diseases. 3: e400. PMID 19333373 DOI: 10.1371/journal.pntd.0000400  0.254
2013 Rimoin AW, Hotez PJ. NTDs in the heart of darkness: the Democratic Republic of Congo's unknown burden of neglected tropical diseases. Plos Neglected Tropical Diseases. 7: e2118. PMID 23936557 DOI: 10.1371/Journal.Pntd.0002118  0.254
2000 Haichou X, Yan W, Shuhua X, Sen L, Yong W, Guangjin S, Weituo W, Bin Z, Drake L, Zheng F, Hotez PJ. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 736-41. PMID 11414422  0.253
2006 Bottazzi ME, Miles AP, Diemert D, Hotez PJ. An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases. Expert Review of Vaccines. 5: 189-98. PMID 16608419 DOI: 10.1586/14760584.5.2.189  0.253
2016 McAtee CP, Seid CA, Hammond M, Hudspeth E, Keegan BP, Liu Z, Wei J, Zhan B, Arjona-Sabido R, Cruz-Chan V, Dumonteil E, Hotez PJ, Bottazzi ME. Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis. Protein Expression and Purification. PMID 27773761 DOI: 10.1016/j.pep.2016.10.008  0.253
2018 Gazzinelli-Guimarães AC, Gazzinelli-Guimarães PH, Nogueira DS, Oliveira FMS, Barbosa FS, Amorim CCO, Cardoso MS, Kraemer L, Caliari MV, Akamatsu MA, Ho PL, Jones KM, Weatherhead J, Bottazzi ME, Hotez PJ, et al. IgG Induced by Vaccination With Extracts Is Protective Against Infection. Frontiers in Immunology. 9: 2535. PMID 30473693 DOI: 10.3389/fimmu.2018.02535  0.253
2023 Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, et al. From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access. Expert Review of Vaccines. 22: 495-500. PMID 37252854 DOI: 10.1080/14760584.2023.2217917  0.252
1981 Rosen NL, Onodera M, Hotez PJ, Bogucki MS, Elce B, Patton C, Konigsberg WH, Cross GA, Richards FF. Trypanosoma congolense: surface glycoproteins of two early bloodstream variants. I. Production of a relapsing infection in rodents. Experimental Parasitology. 52: 210-8. PMID 6168484 DOI: 10.1016/0014-4894(81)90076-X  0.252
2013 Beaumier CM, Gillespie PM, Hotez PJ, Bottazzi ME. New vaccines for neglected parasitic diseases and dengue. Translational Research : the Journal of Laboratory and Clinical Medicine. 162: 144-55. PMID 23578479 DOI: 10.1016/j.trsl.2013.03.006  0.252
2021 Rawal K, Sinha R, Abbasi BA, Chaudhary A, Nath SK, Kumari P, Preeti P, Saraf D, Singh S, Mishra K, Gupta P, Mishra A, Sharma T, Gupta S, Singh P, ... ... Hotez PJ, et al. Identification of vaccine targets in pathogens and design of a vaccine using computational approaches. Scientific Reports. 11: 17626. PMID 34475453 DOI: 10.1038/s41598-021-96863-x  0.252
2022 Hotez PJ, Bottazzi ME. Whole Inactivated Virus and Protein-Based COVID-19 Vaccines. Annual Review of Medicine. 73: 55-64. PMID 34637324 DOI: 10.1146/annurev-med-042420-113212  0.252
2022 Jones KM, Poveda C, Versteeg L, Bottazzi ME, Hotez PJ. Preclinical advances and the immunophysiology of a new therapeutic Chagas disease vaccine. Expert Review of Vaccines. 21: 1185-1203. PMID 35735065 DOI: 10.1080/14760584.2022.2093721  0.252
2014 Parise ME, Hotez PJ, Slutsker L. Neglected parasitic infections in the United States: needs and opportunities. The American Journal of Tropical Medicine and Hygiene. 90: 783-5. PMID 24808243 DOI: 10.4269/ajtmh.13-0727  0.251
2016 Barry MA, Wang Q, Jones KM, Heffernan MJ, Buhaya MH, Beaumier CM, Keegan BP, Zhan B, Dumonteil E, Bottazzi ME, Hotez PJ. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Human Vaccines & Immunotherapeutics. 0. PMID 26890466 DOI: 10.1080/21645515.2015.1119346  0.251
2017 Weatherhead JE, Hotez PJ, Mejia R. The Global State of Helminth Control and Elimination in Children. Pediatric Clinics of North America. 64: 867-877. PMID 28734515 DOI: 10.1016/j.pcl.2017.03.005  0.251
2014 Mejia R, Arévalo A, Vicuña Y, Espinosa P, Chico M, Vaca M, Sandoval C, Hotez P, Cooper P. 1788Detection of Gastrointestinal Parasites by Multi-Parallel Quantitative Real-Time PCR and Associations with Growth Delay in Early Childhood: Findings from a Birth Cohort in Rural Ecuador Open Forum Infectious Diseases. 1: S59-S59. DOI: 10.1093/Ofid/Ofu051.160  0.25
2023 Hotez PJ, Gilbert S, Saville M, Privor-Dumm L, Abdool-Karim S, Thompson D, Excler JL, Kim JH. COVID-19 vaccines and the pandemic: lessons learnt for other neglected diseases and future threats. Bmj Global Health. 8. PMID 37277196 DOI: 10.1136/bmjgh-2023-011883  0.25
2023 Thimmiraju SR, Adhikari R, Villar MJ, Lee J, Liu Z, Kundu R, Chen YL, Sharma S, Ghei K, Keegan B, Versteeg L, Gillespie PM, Ciciriello A, Islam NY, Poveda C, ... ... Hotez PJ, et al. A Recombinant Protein XBB.1.5 RBD/Alum/CpG Vaccine Elicits High Neutralizing Antibody Titers against Omicron Subvariants of SARS-CoV-2. Vaccines. 11. PMID 37896960 DOI: 10.3390/vaccines11101557  0.25
2012 Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. Plos Neglected Tropical Diseases. 6: e1475. PMID 22389729 DOI: 10.1371/journal.pntd.0001475  0.249
2018 Hotez PJ. Human Parasitology and Parasitic Diseases: Heading Towards 2050. Advances in Parasitology. 100: 29-38. PMID 29753341 DOI: 10.1016/bs.apar.2018.03.002  0.248
2021 Bozkurt B, Kamat I, Hotez PJ. Myocarditis With COVID-19 mRNA Vaccines. Circulation. 144: 471-484. PMID 34281357 DOI: 10.1161/CIRCULATIONAHA.121.056135  0.248
2012 Barry MA, Bezek S, Serpa JA, Hotez PJ, Woc-Colburn L. Neglected infections of poverty in Texas and the rest of the United States: management and treatment options. Clinical Pharmacology and Therapeutics. 92: 170-81. PMID 22760004 DOI: 10.1038/clpt.2012.85  0.248
2016 Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. Plos Neglected Tropical Diseases. 10: e0004797. PMID 27387453 DOI: 10.1371/Journal.Pntd.0004797  0.247
2014 Hotez PJ. Neglected parasitic infections and poverty in the United States. Plos Neglected Tropical Diseases. 8: e3012. PMID 25188455 DOI: 10.1371/journal.pntd.0003012  0.247
2023 Yao L, Chemaitelly H, Goldman E, Gudina EK, Khalil A, Ahmed R, James AB, Roca A, Fallah MP, Macnab A, Cho WC, Eikelboom J, Qamar FN, Kremsner P, Oliu-Barton M, ... ... Hotez PJ, et al. Time to establish an international vaccine candidate pool for potential highly infectious respiratory disease: a community's view. Eclinicalmedicine. 64: 102222. PMID 37811488 DOI: 10.1016/j.eclinm.2023.102222  0.247
2017 Hotez P, Aksoy S. PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less. Plos Neglected Tropical Diseases. 11: e0005355. PMID 28426662 DOI: 10.1371/Journal.Pntd.0005355  0.246
2011 Hotez PJ, Gurwith M. Europe's neglected infections of poverty. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 15: e611-9. PMID 21763173 DOI: 10.1016/j.ijid.2011.05.006  0.246
2019 Coelho CH, Rappuoli R, Hotez PJ, Duffy PE. Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction. Trends in Parasitology. PMID 31153722 DOI: 10.1016/J.Pt.2019.04.008  0.244
2021 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, ... ... Hotez PJ, et al. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. Biorxiv : the Preprint Server For Biology. PMID 34031655 DOI: 10.1101/2021.05.20.444848  0.244
2012 Jiang S, Bottazzi ME, Du L, Lustigman S, Tseng CT, Curti E, Jones K, Zhan B, Hotez PJ. Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome. Expert Review of Vaccines. 11: 1405-13. PMID 23252385 DOI: 10.1586/Erv.12.126  0.244
2022 Wei J, Hegde VL, Yanamandra AV, O'Hara MP, Keegan B, Jones KM, Strych U, Bottazzi ME, Zhan B, Sastry KJ, Hotez PJ. Mucosal Vaccination With Recombinant WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice. Frontiers in Immunology. 13: 800295. PMID 35197976 DOI: 10.3389/fimmu.2022.800295  0.243
2003 Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Digestive proteases of blood-feeding nematodes. Trends in Parasitology. 19: 417-23. PMID 12957519 DOI: 10.1016/S1471-4922(03)00189-2  0.242
2013 Barry MA, Simon GG, Mistry N, Hotez PJ. Global trends in neglected tropical disease control and elimination: impact on child health. Archives of Disease in Childhood. 98: 635-41. PMID 23793132 DOI: 10.1136/archdischild-2012-302338  0.242
2022 Pollet J, Strych U, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Jose Villar M, Rani Thimmiraju S, Lopez B, ... ... Hotez PJ, et al. Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern. Vaccine. 40: 3655-3663. PMID 35568591 DOI: 10.1016/j.vaccine.2022.05.007  0.241
2019 Keitel WA, Potter GE, Diemert D, Bethony J, El Sahly HM, Kennedy JK, Patel SM, Plieskatt JL, Jones W, Deye G, Bottazzi ME, Hotez PJ, Atmar RL. A phase 1 study of the safety, reactogenicity, and immunogenicity of a Schistosoma mansoni vaccine with or without glucopyranosyl lipid A aqueous formulation (GLA-AF) in healthy adults from a non-endemic area. Vaccine. PMID 31515141 DOI: 10.1016/J.Vaccine.2019.08.075  0.239
2020 Rostami A, Sepidarkish M, Ma G, Wang T, Ebrahimi M, Fakhri Y, Mirjalali H, Hofmann A, Macpherson CNL, Hotez PJ, Gasser RB. Global prevalence of Toxocara infection in cats. Advances in Parasitology. 109: 615-639. PMID 32381220 DOI: 10.1016/Bs.Apar.2020.01.025  0.239
2020 Rostami A, Riahi SM, Hofmann A, Ma G, Wang T, Behniafar H, Taghipour A, Fakhri Y, Spotin A, Chang BCH, Macpherson CNL, Hotez PJ, Gasser RB. Global prevalence of Toxocara infection in dogs. Advances in Parasitology. 109: 561-583. PMID 32381218 DOI: 10.1016/bs.apar.2020.01.017  0.239
2007 Hotez P, Raff S, Fenwick A, Richards F, Molyneux DH. Recent progress in integrated neglected tropical disease control. Trends in Parasitology. 23: 511-4. PMID 17951109 DOI: 10.1016/J.Pt.2007.08.015  0.239
2008 Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. Plos Neglected Tropical Diseases. 2: e300. PMID 18820747 DOI: 10.1371/journal.pntd.0000300  0.239
2014 Chen WH, Du L, Chag SM, Ma C, Tricoche N, Tao X, Seid CA, Hudspeth EM, Lustigman S, Tseng CT, Bottazzi ME, Hotez PJ, Zhan B, Jiang S. Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate. Human Vaccines & Immunotherapeutics. 10: 648-58. PMID 24355931 DOI: 10.4161/Hv.27464  0.238
2021 Cruz-Chan JV, Villanueva-Lizama LE, Versteeg L, Damania A, Villar MJ, González-López C, Keegan B, Pollet J, Gusovsky F, Hotez PJ, Bottazzi ME, Jones KM. Vaccine-linked chemotherapy induces IL-17 production and reduces cardiac pathology during acute Trypanosoma cruzi infection. Scientific Reports. 11: 3222. PMID 33547365 DOI: 10.1038/s41598-021-82930-w  0.238
2017 Biter AB, Weltje S, Hudspeth EM, Seid CA, McAtee CP, Chen WH, Pollet JB, Strych U, Hotez PJ, Bottazzi ME. Characterization and stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a candidate antigen for a therapeutic vaccine against Chagas disease. Journal of Pharmaceutical Sciences. PMID 29274820 DOI: 10.1016/j.xphs.2017.12.014  0.236
2023 Preeti P, Nath SK, Arambam N, Sharma T, Choudhury PR, Choudhury A, Khanna V, Strych U, Hotez PJ, Bottazzi ME, Rawal K. Vaxi-DL: An Artificial Intelligence-Enabled Platform for Vaccine Development. Methods in Molecular Biology (Clifton, N.J.). 2673: 305-316. PMID 37258923 DOI: 10.1007/978-1-0716-3239-0_21  0.236
2023 Cable J, Graham BS, Koup RA, Seder RA, Karikó K, Pardi N, Barouch DH, Sharma B, Rauch S, Nachbagauer R, Forsell MNE, Schotsaert M, Ellebedy AH, Loré K, Irvine DJ, ... ... Hotez PJ, et al. Progress in vaccine development for infectious diseases-a Keystone Symposia report. Annals of the New York Academy of Sciences. 1524: 65-86. PMID 37020354 DOI: 10.1111/nyas.14975  0.236
2021 Li G, Hoeweler L, Keegan B, Peng J, Scholte L, Hotez P, Bottazzi ME, Diemert D, Bethony J. Potency testing for a recombinant protein vaccine early in clinical development: Lessons from the Tetraspanin 2 vaccine. Vaccine: X. 8: 100100. PMID 34169270 DOI: 10.1016/j.jvacx.2021.100100  0.236
2005 Hotez PJ, Arora S, Bethony J, Bottazzi ME, Loukas A, Correa-Oliveira R, Brooker S. Helminth infections of children: prospects for control. Advances in Experimental Medicine and Biology. 568: 135-44. PMID 16108129 DOI: 10.1007/0-387-25342-4_9  0.235
2017 Akinyemiju T, Abera S, Ahmed M, Alam N, Alemayohu MA, Allen C, Al-Raddadi R, Alvis-Guzman N, Amoako Y, Artaman A, Ayele TA, Barac A, Bensenor I, Berhane A, ... ... Hotez P, et al. The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015. Jama Oncology. PMID 28983565 DOI: 10.1001/Jamaoncol.2017.3055  0.235
2017 Liu Z, Kelleher A, Tabb S, Wei J, Pollet J, Hotez PJ, Bottazzi ME, Zhan B, Asojo OA. Identification, Characterization, and Structure of Tm16 from Trichuris muris. Journal of Parasitology Research. 2017: 4342789. PMID 28884022 DOI: 10.1155/2017/4342789  0.234
2017 Ma G, Holland CV, Wang T, Hofmann A, Fan CK, Maizels RM, Hotez PJ, Gasser RB. Human toxocariasis. The Lancet. Infectious Diseases. PMID 28781085 DOI: 10.1016/S1473-3099(17)30331-6  0.234
2021 Versteeg L, Adhikari R, Poveda C, Villar-Mondragon MJ, Jones KM, Hotez PJ, Bottazzi ME, Tijhaar E, Pollet J. Location and expression kinetics of Tc24 in different life stages of Trypanosoma cruzi. Plos Neglected Tropical Diseases. 15: e0009689. PMID 34478444 DOI: 10.1371/journal.pntd.0009689  0.233
2021 Omer SB, Benjamin RM, Brewer NT, Buttenheim AM, Callaghan T, Caplan A, Carpiano RM, Clinton C, DiResta R, Elharake JA, Flowers LC, Galvani AP, Lakshmanan R, Maldonado YA, McFadden SM, ... ... Hotez PJ, et al. Promoting COVID-19 vaccine acceptance: recommendations from the Lancet Commission on Vaccine Refusal, Acceptance, and Demand in the USA. Lancet (London, England). 398: 2186-2192. PMID 34793741 DOI: 10.1016/S0140-6736(21)02507-1  0.233
2014 McCarty TR, Turkeltaub JA, Hotez PJ. Global progress towards eliminating gastrointestinal helminth infections. Current Opinion in Gastroenterology. 30: 18-24. PMID 24241244 DOI: 10.1097/MOG.0000000000000025  0.232
2018 Hotez PJ, Bottazzi ME, Bethony J, Diemert DD. Advancing the Development of a Human Schistosomiasis Vaccine. Trends in Parasitology. PMID 30455112 DOI: 10.1016/J.Pt.2018.10.005  0.232
2022 Hotez PJ, Matshaba M. Promise of new malaria vaccines. Bmj (Clinical Research Ed.). 379: o2462. PMID 36241198 DOI: 10.1136/bmj.o2462  0.231
2021 Hayon J, Weatherhead J, Hotez PJ, Bottazzi ME, Zhan B. Advances in vaccine development for human trichuriasis. Parasitology. 1-40. PMID 33757603 DOI: 10.1017/S0031182021000500  0.231
2020 Villanueva-Lizama LE, Cruz-Chan JV, Versteeg L, Teh-Poot CF, Hoffman K, Kendricks A, Keegan B, Pollet J, Gusovsky F, Hotez PJ, Bottazzi ME, Jones KM. TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens. Parasite Immunology. e12769. PMID 32592180 DOI: 10.1111/pim.12769  0.231
2005 Hotez P, Bethony J, Brooker S, Albonico M. Eliminating neglected diseases in Africa. Lancet. 365: 2089. PMID 15964442 DOI: 10.1016/S0140-6736(05)66730-X  0.23
2016 Hotez PJ. Neglected Tropical Diseases in the Anthropocene: The Cases of Zika, Ebola, and Other Infections. Plos Neglected Tropical Diseases. 10: e0004648. PMID 27058728 DOI: 10.1371/journal.pntd.0004648  0.23
2023 Hotez PJ. Global Vaccine Access Demands Combating Both Inequity And Hesitancy. Health Affairs (Project Hope). 42: 1681-1688. PMID 38048497 DOI: 10.1377/hlthaff.2023.00775  0.23
2017 Briggs N, Versteeg L, Zhan B, Mejia R, Keegan B, Beaumier C, Sastry J, Elena Bottazzi M, Hotez P. 2257 Journal of Clinical and Translational Science. 1: 60-60. DOI: 10.1017/cts.2017.215  0.229
2014 Hotez PJ, Bottazzi ME, Tseng CT, Zhan B, Lustigman S, Du L, Jiang S. Calling for rapid development of a safe and effective MERS vaccine. Microbes and Infection / Institut Pasteur. 16: 529-31. PMID 24931059 DOI: 10.1016/J.Micinf.2014.05.002  0.228
2022 Kaplan J, Centeno FH, Hayon J, Bottazzi ME, Hotez PJ, Weatherhead JE, Clark E, Woc-Colburn L. Reviewing a Decade of Outpatient Tropical Medicine in Houston, Texas. The American Journal of Tropical Medicine and Hygiene. 106: 1049-1056. PMID 35226869 DOI: 10.4269/ajtmh.21-1059  0.228
2023 Hotez PJ, Bottazzi ME, Kaye PM, Lee BY, Puchner KP. Neglected tropical disease vaccines: hookworm, leishmaniasis, and schistosomiasis. Vaccine. S176-S179. PMID 38407985 DOI: 10.1016/j.vaccine.2023.04.025  0.228
2023 Mahoney R, Hotez PJ, Bottazzi ME. Global regulatory reforms to promote equitable vaccine access in the next pandemic. Plos Global Public Health. 3: e0002482. PMID 37851688 DOI: 10.1371/journal.pgph.0002482  0.228
2022 Rawal K, Sinha R, Nath SK, Preeti P, Kumari P, Gupta S, Sharma T, Strych U, Hotez P, Bottazzi ME. Vaxi-DL: A web-based deep learning server to identify potential vaccine candidates. Computers in Biology and Medicine. 145: 105401. PMID 35381451 DOI: 10.1016/j.compbiomed.2022.105401  0.227
2016 Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, et al. Expression and Purification of an Engineered, Yeast-expressed Leishmania donovani Nucleoside Hydrolase with Immunogenic Properties. Human Vaccines & Immunotherapeutics. 0. PMID 26839079 DOI: 10.1080/21645515.2016.1139254  0.227
2023 Castañeda S, Muñoz M, Hotez PJ, Bottazzi ME, Paniz-Mondolfi AE, Jones KM, Mejia R, Poveda C, Ramírez JD. Microbiome Alterations Driven by Infection in Two Disjunctive Murine Models. Microbiology Spectrum. 11: e0019923. PMID 37140369 DOI: 10.1128/spectrum.00199-23  0.227
2015 Garcia MN, Aguilar D, Gorchakov R, Rossmann SN, Montgomery SP, Rivera H, Woc-Colburn L, Hotez PJ, Murray KO. Evidence of autochthonous Chagas disease in southeastern Texas. The American Journal of Tropical Medicine and Hygiene. 92: 325-30. PMID 25371187 DOI: 10.4269/Ajtmh.14-0238  0.227
2021 Hotez PJ, Nuzhath T, Callaghan T, Colwell B. COVID-19 Vaccine Decisions: Considering the Choices and Opportunities. Microbes and Infection. 104811. PMID 33744495 DOI: 10.1016/j.micinf.2021.104811  0.226
2007 Yamey G, Hotez P. Neglected tropical diseases. Bmj (Clinical Research Ed.). 335: 269-70. PMID 17690342 DOI: 10.1136/Bmj.39281.645035.80  0.226
2019 Wang L, Zou Y, Zhu X, Bottazzi ME, Hotez PJ, Zhan B. China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative. Plos Neglected Tropical Diseases. 13: e0006946. PMID 30677027 DOI: 10.1371/journal.pntd.0006946  0.226
2016 Hotez PJ, Damania A, Naghavi M. Paying for Worms. Plos Neglected Tropical Diseases. 10: e0005092. PMID 28033369 DOI: 10.1371/journal.pntd.0005092  0.226
2016 Harding S, Bird G, Losos E, Aderolili R, Hotez P. International Day of the Tropics: Towards a Better Global Future Etropic: Electronic Journal of Studies in the Tropics. 15. DOI: 10.25120/Etropic.15.2.2016.3538  0.226
2020 Weatherhead JE, Gazzinelli-Guimaraes P, Knight JM, Fujiwara R, Hotez PJ, Bottazzi ME, Corry DB. Host Immunity and Inflammation to Pulmonary Helminth Infections. Frontiers in Immunology. 11: 594520. PMID 33193446 DOI: 10.3389/fimmu.2020.594520  0.225
2022 Nuzhath T, Hotez PJ, Damania A, Liu PS, Colwell B. Creation of a Global Vaccine Risk Index. Plos One. 17: e0272784. PMID 36001622 DOI: 10.1371/journal.pone.0272784  0.225
2023 Excler JL, Saville M, Privor-Dumm L, Gilbert S, Hotez PJ, Thompson D, Abdool-Karim S, Kim JH. Factors, enablers and challenges for COVID-19 vaccine development. Bmj Global Health. 8. PMID 37277195 DOI: 10.1136/bmjgh-2023-011879  0.225
2019 Bottazzi ME, Hotez PJ. "Running the Gauntlet": Formidable challenges in advancing neglected tropical diseases vaccines from development through licensure, and a "Call to Action". Human Vaccines & Immunotherapeutics. PMID 31180271 DOI: 10.1080/21645515.2019.1629254  0.225
2021 Pino M, Abid T, Pereira Ribeiro S, Edara VV, Floyd K, Smith JC, Latif MB, Pacheco-Sanchez G, Dutta D, Wang S, Gumber S, Kirejczyk S, Cohen J, Stammen RL, Jean SM, ... ... Hotez PJ, et al. A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates. Science Immunology. 6. PMID 34266981 DOI: 10.1126/sciimmunol.abh3634  0.224
2020 Chen WH, Strych U, Hotez PJ, Bottazzi ME. The SARS-CoV-2 Vaccine Pipeline: an Overview. Current Tropical Medicine Reports. 1-4. PMID 32219057 DOI: 10.1007/s40475-020-00201-6  0.223
2018 Hotez PJ. The Global Fight to Develop Antipoverty Vaccines in the Antivax Era. Human Vaccines & Immunotherapeutics. 0. PMID 29393710 DOI: 10.1080/21645515.2018.1430542  0.223
1998 Shuxian L, Guangchen S, Yuxin X, McManus DP, Hotez PJ. Progress in the development of a vaccine against schistosomiasis in China. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. 2: 176-80. PMID 9625614  0.223
2021 Sah P, Vilches TN, Moghadas SM, Fitzpatrick MC, Singer BH, Hotez PJ, Galvani AP. Accelerated vaccine rollout is imperative to mitigate highly transmissible COVID-19 variants. Eclinicalmedicine. 35: 100865. PMID 33937735 DOI: 10.1016/j.eclinm.2021.100865  0.223
2017 Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ. Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate. Journal of Pharmaceutical Sciences. PMID 28456726 DOI: 10.1016/j.xphs.2017.04.037  0.222
2020 Chen WH, Hotez PJ, Bottazzi ME. Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19. Human Vaccines & Immunotherapeutics. 1-4. PMID 32298218 DOI: 10.1080/21645515.2020.1740560  0.222
2024 Bartsch SM, O'Shea KJ, Weatherwax C, Strych U, Velmurugan K, John DC, Bottazzi ME, Hussein M, Martinez MF, Chin KL, Ciciriello A, Heneghan J, Dibbs A, Scannell SA, Hotez PJ, et al. What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective? The Journal of Infectious Diseases. PMID 38581432 DOI: 10.1093/infdis/jiae179  0.221
2000 Shuhua X, Hotez PJ, Tanner M. Artemether, an effective new agent for chemoprophylaxis against shistosomiasis in China: its in vivo effect on the biochemical metabolism of the Asian schistosome. The Southeast Asian Journal of Tropical Medicine and Public Health. 31: 724-32. PMID 11414420  0.221
2015 Garcia MN, Hernandez D, Gorchakov R, Murray KO, Hotez PJ. The 1899 United States Kissing Bug Epidemic. Plos Neglected Tropical Diseases. 9: e0004117. PMID 26719888 DOI: 10.1371/Journal.Pntd.0004117  0.221
2018 Hotez PJ, Wolf JE. Vaccines Hesitancy and the Dermatologist. Skinmed. 16: 219-221. PMID 30207522  0.221
2021 Lee J, Liu Z, Chen WH, Wei J, Kundu R, Adhikari R, Rivera JA, Gillespie PM, Strych U, Zhan B, Hotez PJ, Bottazzi ME. Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain-based vaccine candidate, RBD219-N1C1. Applied Microbiology and Biotechnology. PMID 33959781 DOI: 10.1007/s00253-021-11281-3  0.22
2017 Hotez P, Bundy DAP. The PLOS Neglected Tropical Diseases decade. Plos Neglected Tropical Diseases. 11: e0005479. PMID 28426658 DOI: 10.1371/Journal.Pntd.0005479  0.22
2016 Beaumier CM, Gillespie PM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. PMID 27026146 DOI: 10.1016/j.vaccine.2016.03.074  0.22
2002 Mingjie W, Shuhua X, Junjie C, Bin L, Cheng F, Weixia S, Hotez P. Albendazole-soybean oil emulsion for the treatment of human cystic echinococcosis: evaluation of bioavailability and bioequivalence. Acta Tropica. 83: 177-81. PMID 12088859 DOI: 10.1016/S0001-706X(02)00096-7  0.218
2020 Hotez PJ, Nuzhath T, Colwell B. Combating vaccine hesitancy and other 21st century social determinants in the global fight against measles. Current Opinion in Virology. 41: 1-7. PMID 32113136 DOI: 10.1016/j.coviro.2020.01.001  0.218
2021 Nolan MS, Murray KO, Mejia R, Hotez PJ, Villar Mondragon MJ, Rodriguez S, Palacios JR, Murcia Contreras WE, Lynn MK, Torres ME, Monroy Escobar MC. Elevated Pediatric Chagas Disease Burden Complicated by Concomitant Intestinal Parasites and Malnutrition in El Salvador. Tropical Medicine and Infectious Disease. 6. PMID 34067079 DOI: 10.3390/tropicalmed6020072  0.218
2023 Nguyen DM, Poveda C, Pollet J, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection. Plos Neglected Tropical Diseases. 17: e0011519. PMID 37988389 DOI: 10.1371/journal.pntd.0011519  0.218
2022 Hotez PJ. COVID-19 vaccines: the imperfect instruments of vaccine diplomacy. Journal of Travel Medicine. 29. PMID 35608393 DOI: 10.1093/jtm/taac063  0.217
2013 Bacon KM, Hotez PJ, Kruchten SD, Kamhawi S, Bottazzi ME, Valenzuela JG, Lee BY. The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas. Vaccine. 31: 480-6. PMID 23176979 DOI: 10.1016/J.Vaccine.2012.11.032  0.217
2023 Hotez PJ. SARS-CoV-2 variants offer a second chance to fix vaccine inequities. Nature Reviews. Microbiology. 21: 127-128. PMID 36324031 DOI: 10.1038/s41579-022-00824-8  0.217
2014 Hotez PJ, Woc-Colburn L, Bottazzi ME. Neglected tropical diseases in Central America and Panama: review of their prevalence, populations at risk and impact on regional development. International Journal For Parasitology. 44: 597-603. PMID 24846528 DOI: 10.1016/j.ijpara.2014.04.001  0.217
2023 Privor-Dumm L, Excler JL, Gilbert S, Abdool Karim SS, Hotez PJ, Thompson D, Kim JH. Vaccine access, equity and justice: COVID-19 vaccines and vaccination. Bmj Global Health. 8. PMID 37290896 DOI: 10.1136/bmjgh-2023-011881  0.217
2010 Hotez PJ, Ehrenberg JP. Escalating the global fight against neglected tropical diseases through interventions in the Asia Pacific region. Advances in Parasitology. 72: 31-53. PMID 20624527 DOI: 10.1016/S0065-308X(10)72002-9  0.217
2024 Bartsch SM, O'Shea KJ, John DC, Strych U, Bottazzi ME, Martinez MF, Ciciriello A, Chin KL, Weatherwax C, Velmurugan K, Heneghan J, Scannell SA, Hotez PJ, Lee BY. The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study. Eclinicalmedicine. 68: 102369. PMID 38545093 DOI: 10.1016/j.eclinm.2023.102369  0.216
2021 Bartsch SM, O'Shea KJ, Wedlock PT, Strych U, Ferguson MC, Bottazzi ME, Randall SL, Siegmund SS, Cox SN, Hotez PJ, Lee BY. The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine. American Journal of Preventive Medicine. PMID 33632650 DOI: 10.1016/j.amepre.2021.01.001  0.215
2019 Hotez P. DR Congo and Nigeria: New neglected tropical disease threats and solutions for the bottom 40. Plos Neglected Tropical Diseases. 13: e0007145. PMID 31393879 DOI: 10.1371/Journal.Pntd.0007145  0.215
2013 Kline K, McCarthy JS, Pearson M, Loukas A, Hotez PJ. Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. Plos Neglected Tropical Diseases. 7: e1755. PMID 23383349 DOI: 10.1371/journal.pntd.0001755  0.214
2021 Figueroa JP, Hotez PJ, Batista C, Ben Amor Y, Ergonul O, Gilbert S, Gursel M, Hassanain M, Kang G, Kaslow DC, Kim JH, Lall B, Larson H, Naniche D, Sheahan T, et al. Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed. Plos Medicine. 18: e1003772. PMID 34516558 DOI: 10.1371/journal.pmed.1003772  0.214
2023 Nguyen DM, Poveda C, Pollet J, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic infection. Biorxiv : the Preprint Server For Biology. PMID 37503013 DOI: 10.1101/2023.07.11.548497  0.214
2018 Bartsch SM, Asti L, Cox S, Durham DP, Randall S, Hotez PJ, Galvani AP, Lee BY. What is the Value of Different Zika Vaccination Strategies to Prevent and Mitigate Zika Outbreaks. The Journal of Infectious Diseases. PMID 30544164 DOI: 10.1093/Infdis/Jiy688  0.214
2017 Lo NC, Hotez PJ. Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States. Jama Pediatrics. PMID 28738137 DOI: 10.1001/jamapediatrics.2017.1695  0.213
2021 Nuzhath T, Ajayi KV, Fan Q, Hotez P, Colwell B, Callaghan T, Regan AK. Childhood immunization during the COVID-19 pandemic in Texas. Vaccine. PMID 34020814 DOI: 10.1016/j.vaccine.2021.04.050  0.213
2022 Hotez PJ. Malnutrition vaccines for an imminent global food catastrophe. Trends in Pharmacological Sciences. 43: 994-997. PMID 36100482 DOI: 10.1016/j.tips.2022.08.007  0.212
2012 Molyneux D, Malecela M, Savioli L, Fenwick A, Hotez P. Will increased funding for neglected tropical diseases really make poverty history? - Authors' reply The Lancet. 379: 1098-1100. DOI: 10.1016/S0140-6736(12)60454-1  0.212
2008 Hotez PJ. Neglected infections of poverty in the United States of America. Plos Neglected Tropical Diseases. 2: e256. PMID 18575621 DOI: 10.1371/journal.pntd.0000256  0.211
2021 Bartsch SM, Wedlock PT, O'Shea KJ, Cox SN, Strych U, Nuzzo JB, Ferguson MC, Bottazzi ME, Siegmund SS, Hotez PJ, Lee BY. Lives and Costs Saved by Expanding and Expediting COVID-19 Vaccination. The Journal of Infectious Diseases. PMID 33954775 DOI: 10.1093/infdis/jiab233  0.211
2023 Hotez PJ. Global Vaccinations: New Urgency to Surmount a Triple Threat of Illness, Antiscience, and Anti-Semitism. Rambam Maimonides Medical Journal. 14. PMID 36719666 DOI: 10.5041/RMMJ.10491  0.211
2019 Bartsch SM, Bottazzi ME, Asti L, Strych U, Meymandi S, Falcón-Lezama JA, Randall S, Hotez PJ, Lee BY. Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients. Vaccine. PMID 31104883 DOI: 10.1016/j.vaccine.2019.05.028  0.211
2014 Hotez PJ. "Vaccine diplomacy": historical perspectives and future directions. Plos Neglected Tropical Diseases. 8: e2808. PMID 24968231 DOI: 10.1371/journal.pntd.0002808  0.21
2021 Sah P, Moghadas SM, Vilches TN, Shoukat A, Singer BH, Hotez PJ, Schneider EC, Galvani AP. Implications of suboptimal COVID-19 vaccination coverage in Florida and Texas. The Lancet. Infectious Diseases. 21: 1493-1494. PMID 34627498 DOI: 10.1016/S1473-3099(21)00620-4  0.21
2010 Hotez PJ. Peace through vaccine diplomacy. Science (New York, N.Y.). 327: 1301. PMID 20223952 DOI: 10.1126/science.1189028  0.21
2021 Hotez PJ, Narayan KMV. Restoring Vaccine Diplomacy. Jama. 325: 2337-2338. PMID 34047758 DOI: 10.1001/jama.2021.7439  0.209
2021 Hotez PJ. Vaccinating cassandra. Eclinicalmedicine. 100711. PMID 33426513 DOI: 10.1016/j.eclinm.2020.100711  0.209
2022 Hotez PJ. Will anti-vaccine activism in the USA reverse global goals? Nature Reviews. Immunology. 22: 525-526. PMID 35915141 DOI: 10.1038/s41577-022-00770-9  0.209
2006 Hotez P, Stoever K, Fenwick A, Molyneux D, Savioli L. The Lancet's chronic diseases series. Lancet. 367: 563-4; author reply . PMID 16488790 DOI: 10.1016/S0140-6736(06)68213-5  0.208
2001 Hotez PJ. Vaccines as instruments of foreign policy. The new vaccines for tropical infectious diseases may have unanticipated uses beyond fighting diseases. Embo Reports. 2: 862-8. PMID 11600443 DOI: 10.1093/embo-reports/kve215  0.208
2022 Mello MM, Opel DJ, Benjamin RM, Callaghan T, DiResta R, Elharake JA, Flowers LC, Galvani AP, Salmon DA, Schwartz JL, Brewer NT, Buttenheim AM, Carpiano RM, Clinton C, Hotez PJ, et al. Effectiveness of vaccination mandates in improving uptake of COVID-19 vaccines in the USA. Lancet (London, England). 400: 535-538. PMID 35817078 DOI: 10.1016/S0140-6736(22)00875-3  0.208
2021 Naniche D, Hotez P, Bottazzi ME, Ergonul O, Figueroa JP, Gilbert S, Gursel M, Hassanain M, Kang G, Kaslow D, Kim JH, Lall B, Larson H, Sheahan T, Shoham S, et al. Beyond the jab: A need for global coordination of pharmacovigilance for COVID-19 vaccine deployment. Eclinicalmedicine. 36: 100925. PMID 34099998 DOI: 10.1016/j.eclinm.2021.100925  0.208
2020 Hotez PJ, Corry DB, Strych U, Bottazzi ME. COVID-19 vaccines: neutralizing antibodies and the alum advantage. Nature Reviews. Immunology. 20: 399-400. PMID 32499636 DOI: 10.1038/s41577-020-0358-6  0.208
2011 Hotez PJ, Aksoy S. An interfaith dialogue on the neglected tropical diseases. Plos Neglected Tropical Diseases. 5: e1240. PMID 22206020 DOI: 10.1371/Journal.Pntd.0001240  0.208
2018 Hotez PJ. Minutes to midnight: Turning back the Doomsday Clock through neglected disease vaccine diplomacy. Plos Neglected Tropical Diseases. 12: e0006676. PMID 30235204 DOI: 10.1371/journal.pntd.0006676  0.207
2022 Brewer NT, Buttenheim AM, Clinton CV, Mello MM, Benjamin RM, Callaghan T, Caplan A, Carpiano RM, DiResta R, Elharake JA, Flowers LC, Galvani AP, Hotez PJ, Lakshmanan R, Maldonado YA, et al. Incentives for COVID-19 vaccination. Lancet Regional Health. Americas. 8: 100205. PMID 35229080 DOI: 10.1016/j.lana.2022.100205  0.207
2023 Opel DJ, Brewer NT, Buttenheim AM, Callaghan T, Carpiano RM, Clinton C, Elharake JA, Flowers LC, Galvani AP, Hotez PJ, Schwartz JL, Benjamin RM, Caplan A, DiResta R, Lakshmanan R, et al. The legacy of the COVID-19 pandemic for childhood vaccination in the USA. Lancet (London, England). 401: 75-78. PMID 36309017 DOI: 10.1016/S0140-6736(22)01693-2  0.207
2019 Hotez PJ. The rise or fall of Neglected Tropical Diseases in East Asia Pacific. Acta Tropica. 105182. PMID 31550453 DOI: 10.1016/j.actatropica.2019.105182  0.207
2010 Brooker S, Hotez PJ, Bundy DA. The global atlas of helminth infection: mapping the way forward in neglected tropical disease control. Plos Neglected Tropical Diseases. 4: e779. PMID 20668545 DOI: 10.1371/journal.pntd.0000779  0.207
2021 Pandey A, Sah P, Moghadas SM, Mandal S, Banerjee S, Hotez PJ, Galvani AP. Challenges facing COVID-19 vaccination in India: Lessons from the initial vaccine rollout. Journal of Global Health. 11: 03083. PMID 34221355 DOI: 10.7189/jogh.11.03083  0.207
2023 Carpiano RM, Callaghan T, DiResta R, Brewer NT, Clinton C, Galvani AP, Lakshmanan R, Parmet WE, Omer SB, Buttenheim AM, Benjamin RM, Caplan A, Elharake JA, Flowers LC, Maldonado YA, ... ... Hotez PJ, et al. Confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era. Lancet (London, England). 401: 967-970. PMID 36871571 DOI: 10.1016/S0140-6736(23)00136-8  0.207
2012 Hotez P. Foreword to Parasitic Helminths: Targets, Screens, Drugs and Vaccines Parasitic Helminths: Targets, Screens, Drugs and Vaccines. v-vi. DOI: 10.1002/9783527652969  0.206
2019 Paniz-Mondolfi AE, Tami A, Grillet ME, Márquez M, Hernández-Villena J, Escalona-Rodríguez MA, Blohm GM, Mejías I, Urbina-Medina H, Rísquez A, Castro J, Carvajal A, Walter C, López MG, Schwabl P, ... ... Hotez PJ, et al. Resurgence of Vaccine-Preventable Diseases in Venezuela as a Regional Public Health Threat in the Americas. Emerging Infectious Diseases. 25. PMID 30698523 DOI: 10.3201/eid2504.181305  0.206
2011 Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica. 120: S158-68. PMID 20655862 DOI: 10.1016/J.Actatropica.2010.07.006  0.205
2016 Hotez PJ. Texas and Its Measles Epidemics. Plos Medicine. 13: e1002153. PMID 27780206 DOI: 10.1371/journal.pmed.1002153  0.204
2020 Chen WH, Tao X, Agrawal A, Algaissi A, Peng BH, Pollet J, Strych U, Bottazzi ME, Hotez PJ, Lustigman S, Du L, Jiang S, Tseng CK. Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Alum Induces Protective Immunity and Reduces Immune Enhancement. Biorxiv : the Preprint Server For Biology. PMID 32511385 DOI: 10.1101/2020.05.15.098079  0.204
2019 Nyathi S, Karpel HC, Sainani KL, Maldonado Y, Hotez PJ, Bendavid E, Lo NC. The 2016 California policy to eliminate nonmedical vaccine exemptions and changes in vaccine coverage: An empirical policy analysis. Plos Medicine. 16: e1002994. PMID 31869328 DOI: 10.1371/Journal.Pmed.1002994  0.204
2021 Hotez E, Hotez PJ, Rosenau KA, Kuo AA. Prioritizing COVID-19 vaccinations for individuals with intellectual and developmental disabilities. Eclinicalmedicine. 100749. PMID 33585807 DOI: 10.1016/j.eclinm.2021.100749  0.204
2010 Bourhy H, Dautry-Varsat A, Hotez PJ, Salomon J. Rabies, still neglected after 125 years of vaccination. Plos Neglected Tropical Diseases. 4: e839. PMID 21152052 DOI: 10.1371/journal.pntd.0000839  0.203
2022 Pollet J, Strych U, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, Thimmiraju SR, Lopez B, ... ... Hotez P, et al. Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern. Biorxiv : the Preprint Server For Biology. PMID 34268512 DOI: 10.1101/2021.07.06.451353  0.202
2024 Carpiano RM, Callahan T, Elharake JA, Hotez P. Vaccination and the defence of democracy - Authors' reply. Lancet (London, England). 403: 529-530. PMID 38341249 DOI: 10.1016/S0140-6736(23)01895-0  0.202
2021 Hotez PJ, Batista C, Amor YB, Ergonul O, Figueroa JP, Gilbert S, Gursel M, Hassanain M, Kang G, Kaslow DC, Kim JH, Lall B, Larson H, Naniche D, Sheahan T, et al. Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic. Eclinicalmedicine. 39: 101053. PMID 34368661 DOI: 10.1016/j.eclinm.2021.101053  0.202
2017 McKenna ML, McAtee S, Bryan PE, Jeun R, Ward T, Kraus J, Bottazzi ME, Hotez PJ, Flowers CC, Mejia R. Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. The American Journal of Tropical Medicine and Hygiene. PMID 29016326 DOI: 10.4269/ajtmh.17-0396  0.201
2012 Hotez PJ, Bottazzi ME, Dumonteil E, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Cravioto MB, Tapia-Conyer R. Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases. Plos Neglected Tropical Diseases. 6: e1497. PMID 22479656 DOI: 10.1371/Journal.Pntd.0001497  0.201
2015 Weatherhead JE, Hotez PJ. Worm Infections in Children. Pediatrics in Review / American Academy of Pediatrics. 36: 341-52; quiz 353-4. PMID 26232464 DOI: 10.1542/pir.36-8-341  0.201
2007 Alexander N, Bethony J, Corrêa-Oliveira R, Rodrigues LC, Hotez P, Brooker S. Repeatability of paired counts. Statistics in Medicine. 26: 3566-77. PMID 17091531 DOI: 10.1002/Sim.2724  0.201
2020 Chen WH, Tao X, Agrawal AS, Algaissi A, Peng BH, Pollet J, Strych U, Bottazzi ME, Hotez PJ, Lustigman S, Du L, Jiang S, Tseng CK. Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement. Vaccine. PMID 33039209 DOI: 10.1016/j.vaccine.2020.09.061  0.201
2020 Singer R, Xu H, Herrera LN, Villar MJ, Faust K, Hotez PJ, Aiken A, Mejia R. Prevalence of Intestinal Parasites in a Low-Income Texas Community. The American Journal of Tropical Medicine and Hygiene. PMID 32207401 DOI: 10.4269/ajtmh.19-0915  0.201
2017 Hotez PJ. Developing and financing neglected disease vaccines in our new era of "blue marble health" and the anthropocene epoch. Vaccine. PMID 28262333 DOI: 10.1016/j.vaccine.2017.02.002  0.2
2020 Callaghan T, Moghtaderi A, Lueck JA, Hotez P, Strych U, Dor A, Fowler EF, Motta M. Correlates and disparities of intention to vaccinate against COVID-19. Social Science & Medicine (1982). 113638. PMID 33414032 DOI: 10.1016/j.socscimed.2020.113638  0.2
2020 Ma G, Rostami A, Wang T, Hofmann A, Hotez PJ, Gasser RB. Global and regional seroprevalence estimates for human toxocariasis: A call for action. Advances in Parasitology. 109: 275-290. PMID 32381202 DOI: 10.1016/Bs.Apar.2020.01.011  0.199
2015 Hotez PJ. Vaccine Science Diplomacy: Expanding Capacity to Prevent Emerging and Neglected Tropical Diseases Arising from Islamic State (IS)--Held Territories. Plos Neglected Tropical Diseases. 9: e0003852. PMID 26402466 DOI: 10.1371/journal.pntd.0003852  0.197
2018 Mokdad AH, Ballestros K, Echko M, Glenn S, Olsen HE, Mullany E, Lee A, Khan AR, Ahmadi A, Ferrari AJ, Kasaeian A, Werdecker A, Carter A, Zipkin B, ... ... Hotez P, et al. The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. Jama. 319: 1444-1472. PMID 29634829 DOI: 10.1001/Jama.2018.0158  0.196
2021 Hotez P. COVID vaccines: time to confront anti-vax aggression. Nature. 592: 661. PMID 33907330 DOI: 10.1038/d41586-021-01084-x  0.196
2011 Hotez PJ. America's most distressed areas and their neglected infections: the United States Gulf Coast and the District of Columbia. Plos Neglected Tropical Diseases. 5: e843. PMID 21468312 DOI: 10.1371/journal.pntd.0000843  0.195
2020 Bartsch SM, Stokes-Cawley OJ, Buekens P, Asti L, Bottazzi ME, Strych U, Wedlock PT, Mitgang EA, Meymandi S, Falcon-Lezama JA, Hotez PJ, Lee BY. The potential economic value of a therapeutic Chagas disease vaccine for pregnant women to prevent congenital transmission. Vaccine. PMID 32171575 DOI: 10.1016/j.vaccine.2020.02.078  0.194
2011 Nair SS, Bommana A, Bethony JM, Lyon AJ, Ohshiro K, Pakala SB, Rinaldi G, Keegan B, Suttiprapa S, Periago MV, Hotez PJ, Brindley PJ, Kumar R. The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology (Baltimore, Md.). 54: 285-95. PMID 21488078 DOI: 10.1002/Hep.24354  0.194
2019 Mondolfi AEP, Grillet ME, Tami A, Oliveira-Miranda MA, Noguera LD, Hotez P, Oletta JF. Venezuela's upheaval threatens Yanomami. Science (New York, N.Y.). 365: 766-767. PMID 31439788 DOI: 10.1126/Science.Aay6003  0.194
2020 Bartsch SM, Asti L, Stokes-Cawley OJ, Sim SY, Bottazzi ME, Hotez PJ, Lee BY. The Potential Economic Value of a Zika Vaccine for a Woman of Childbearing Age. American Journal of Preventive Medicine. PMID 31980305 DOI: 10.1016/j.amepre.2019.10.023  0.194
2020 Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Wedlock PT, Strych U, McKinnell JA, Siegmund SS, Cox SN, Hotez PJ, Lee BY. Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention. American Journal of Preventive Medicine. PMID 32778354 DOI: 10.1016/j.amepre.2020.06.011  0.193
2022 Maldonado YA, O'Leary S, Hotez P. Vaccine Exemptions and the Risk of Continued Disease Outbreaks. Pediatrics. 149. PMID 34866155 DOI: 10.1542/peds.2021-054369  0.193
2010 Waldor MK, Hotez PJ, Clemens JD. A national cholera vaccine stockpile--a new humanitarian and diplomatic resource. The New England Journal of Medicine. 363: 2279-82. PMID 21105832 DOI: 10.1056/Nejmp1012300  0.193
2006 Brooker S, Alexander N, Geiger S, Moyeed RA, Stander J, Fleming F, Hotez PJ, Correa-Oliveira R, Bethony J. Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. International Journal For Parasitology. 36: 1143-51. PMID 16814294 DOI: 10.1016/J.Ijpara.2006.05.009  0.191
2014 Rajagopal S, Hotez PJ, Bundy DA. Micronutrient supplementation and deworming in children with geohelminth infections. Plos Neglected Tropical Diseases. 8: e2920. PMID 25101963 DOI: 10.1371/journal.pntd.0002920  0.19
2021 Sharfstein JM, Callaghan T, Carpiano RM, Sgaier SK, Brewer NT, Galvani AP, Lakshmanan R, McFadden SM, Reiss DR, Salmon DA, Hotez PJ. Uncoupling vaccination from politics: a call to action. Lancet (London, England). 398: 1211-1212. PMID 34537104 DOI: 10.1016/S0140-6736(21)02099-7  0.189
2021 Hotez P, Batista C, Ergonul O, Figueroa JP, Gilbert S, Gursel M, Hassanain M, Kang G, Kim JH, Lall B, Larson H, Naniche D, Sheahan T, Shoham S, Wilder-Smith A, et al. Correcting COVID-19 vaccine misinformation: Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force Members. Eclinicalmedicine. 33: 100780. PMID 33718854 DOI: 10.1016/j.eclinm.2021.100780  0.189
2001 HOTEZ P. BOOK REVIEW: Manual of Tropical Pediatrics Journal of Parasitology. 87: 638-638. DOI: 10.1645/0022-3395(2001)087[0638:Br]2.0.Co;2  0.189
2015 Garcia MN, Murray KO, Hotez PJ, Rossmann SN, Gorchakov R, Ontiveros A, Woc-Colburn L, Bottazzi ME, Rhodes CE, Ballantyne CM, Aguilar D. Development of chagas cardiac manifestations among Texas blood donors. The American Journal of Cardiology. 115: 113-7. PMID 25456877 DOI: 10.1016/J.Amjcard.2014.09.050  0.189
2003 de Silva NR, Brooker S, Hotez PJ, Montresor A, Engels D, Savioli L. Soil-transmitted helminth infections: updating the global picture. Trends in Parasitology. 19: 547-51. PMID 14642761  0.188
2021 Hotez PJ. Anti-science kills: From Soviet embrace of pseudoscience to accelerated attacks on US biomedicine. Plos Biology. 19: e3001068. PMID 33507935 DOI: 10.1371/journal.pbio.3001068  0.188
2020 Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Cox SN, Strych U, McKinnell JA, Wedlock PT, Siegmund SS, Hotez PJ, Lee BY. How Efficacious Must a COVID-19 Coronavirus Vaccine be to Prevent or Stop an Epidemic by Itself. Medrxiv : the Preprint Server For Health Sciences. PMID 32511569 DOI: 10.1101/2020.05.29.20117184  0.187
2020 Hotez PJ, Corry DB, Bottazzi ME. COVID-19 vaccine design: the Janus face of immune enhancement. Nature Reviews. Immunology. PMID 32346094 DOI: 10.1038/s41577-020-0323-4  0.186
2019 Hotez PJ. Whatever happened to China's neglected tropical diseases? Infectious Diseases of Poverty. 8: 85. PMID 31578156 DOI: 10.1186/s40249-019-0598-5  0.186
2016 Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, Tapia-Conyer R, Reeder JC. Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. Plos Neglected Tropical Diseases. 10: e0003895. PMID 26934395 DOI: 10.1371/Journal.Pntd.0003895  0.185
2022 Bartsch SM, O'Shea KJ, Chin KL, Strych U, Ferguson MC, Bottazzi ME, Wedlock PT, Cox SN, Siegmund SS, Hotez PJ, Lee BY. Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study. The Lancet. Public Health. 7: e356-e365. PMID 35276093 DOI: 10.1016/S2468-2667(22)00040-8  0.184
2011 Nair SS, Bommana A, Pakala SB, Ohshiro K, Lyon AJ, Suttiprapa S, Periago MV, Laha T, Hotez PJ, Bethony JM, Sripa B, Brindley PJ, Kumar R. Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology (Baltimore, Md.). 54: 1388-97. PMID 21725997 DOI: 10.1002/Hep.24518  0.184
2023 Nath SK, Pankajakshan P, Sharma T, Kumari P, Shinde S, Garg N, Mathur K, Arambam N, Harjani D, Raj M, Kwatra G, Venkatesh S, Choudhoury A, Bano S, Tayal P, ... ... Hotez PJ, et al. A Data-Driven Approach to Construct a Molecular Map of to Identify Drugs and Vaccine Targets. Vaccines. 11. PMID 36851145 DOI: 10.3390/vaccines11020267  0.182
2017 Hotez PJ. Russian-United States vaccine science diplomacy: Preserving the legacy. Plos Neglected Tropical Diseases. 11: e0005320. PMID 28542186 DOI: 10.1371/journal.pntd.0005320  0.182
2022 Hotez P. Communicating science and protecting scientists in a time of political instability. Trends in Molecular Medicine. 28: 173-175. PMID 35063364 DOI: 10.1016/j.molmed.2022.01.001  0.181
2006 Hotez P, Gupta R, Mahoney R, Poste G. Incorporating appropriate technology into North American schools of public health. Revista Panamericana De Salud PãºBlica = Pan American Journal of Public Health. 19: 118-23. PMID 16551386 DOI: 10.1590/S1020-49892006000200007  0.181
2018 Blum AJ, Hotez PJ. Global "worming": Climate change and its projected general impact on human helminth infections. Plos Neglected Tropical Diseases. 12: e0006370. PMID 30024871 DOI: 10.1371/journal.pntd.0006370  0.181
2012 Hotez PJ, Asojo OA, Adesina AM. Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. Plos Neglected Tropical Diseases. 6: e1600. PMID 22860138 DOI: 10.1371/Journal.Pntd.0001600  0.179
1981 Onodera M, Rosen NL, Lifter J, Hotez PJ, Bogucki MS, Davis G, Patton CL, Konigsberg WH, Richards FF. Trypanosoma congolense: surface glycoproteins of two early bloodstream variants. II. Purification and partial chemical characterization. Experimental Parasitology. 52: 427-39. PMID 7318988 DOI: 10.1016/0014-4894(81)90102-8  0.178
2020 Hotez PJ, Bottazzi ME. Developing a low-cost and accessible COVID-19 vaccine for global health. Plos Neglected Tropical Diseases. 14: e0008548. PMID 32726304 DOI: 10.1371/journal.pntd.0008548  0.175
2018 Gunter SM, Versteeg L, Jones KM, Brian KP, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production. Parasite Immunology. e12585. PMID 30132929 DOI: 10.1111/pim.12585  0.174
2013 Brindley PJ, Hotez PJ. Break Out: urogenital schistosomiasis and Schistosoma haematobium infection in the post-genomic era. Plos Neglected Tropical Diseases. 7: e1961. PMID 23556007 DOI: 10.1371/Journal.Pntd.0001961  0.174
2014 Hotez PJ. Neglected infections of poverty in the United States and their effects on the brain. Jama Psychiatry. 71: 1099-100. PMID 25103827 DOI: 10.1001/jamapsychiatry.2014.1045  0.173
2022 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, ... ... Hotez PJ, et al. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Science Translational Medicine. 14: eabj5305. PMID 34783582 DOI: 10.1126/scitranslmed.abj5305  0.172
2011 Jex AR, Lim YA, Bethony JM, Hotez PJ, Young ND, Gasser RB. Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Advances in Parasitology. 74: 231-65. PMID 21295679 DOI: 10.1016/B978-0-12-385897-9.00004-5  0.171
2020 Ruscio BA, Hotez P. Expanding global and national influenza vaccine systems to match the COVID-19 pandemic response. Vaccine. PMID 33121842 DOI: 10.1016/j.vaccine.2020.10.055  0.171
2020 Hotez P. COVID19 in America: An October Plan. Microbes and Infection. PMID 32712199 DOI: 10.1016/J.Micinf.2020.07.003  0.171
2019 Engelman D, Cantey PT, Marks M, Solomon AW, Chang AY, Chosidow O, Enbiale W, Engels D, Hay RJ, Hendrickx D, Hotez PJ, Kaldor JM, Kama M, Mackenzie CD, McCarthy JS, et al. The public health control of scabies: priorities for research and action. Lancet (London, England). PMID 31178154 DOI: 10.1016/S0140-6736(19)31136-5  0.17
2020 Bottazzi ME, Strych U, Hotez PJ, Corry DB. Coronavirus vaccine-associated lung immunopathology-what is the significance? Microbes and Infection. PMID 32599077 DOI: 10.1016/j.micinf.2020.06.007  0.17
2017 Hotez PJ. The poverty-related neglected diseases: Why basic research matters. Plos Biology. 15: e2004186. PMID 29121043 DOI: 10.1371/journal.pbio.2004186  0.17
2014 Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, et al. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3952-64. PMID 24891519 DOI: 10.1096/Fj.14-251967  0.17
2022 Pierce CA, Herold KC, Herold BC, Chou J, Randolph A, Kane B, McFarland S, Gurdasani D, Pagel C, Hotez P, Cobey S, Hensley SE. COVID-19 and children. Science (New York, N.Y.). 377: 1144-1149. PMID 36074833 DOI: 10.1126/science.ade1675  0.169
2002 Hotez PJ. Reducing the Global Burden of Human Parasitic Diseases Comparative Parasitology. 69: 140-145. DOI: 10.1654/1525-2647(2002)069[0140:RTGBOH]2.0.CO;2  0.169
2020 Rostami A, Riahi SM, Gamble HR, Fakhri Y, Shiadeh MN, Danesh M, Behniafar H, Paktinat S, Foroutan M, Mokdad AH, Hotez PJ, Gasser RB. Global prevalence of latent toxoplasmosis in pregnant women: a systematic review and meta-analysis. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 31972316 DOI: 10.1016/J.Cmi.2020.01.008  0.168
2018 Weatherhead JE, Porter P, Coffey A, Haydel D, Versteeg L, Zhan B, Gazzinelli Guimarães AC, Fujiwara R, Jaramillo AM, Bottazzi ME, Hotez PJ, Corry DB, Beaumier CM. Larval Infection and Lung Invasion Directly Induces Severe Allergic Airway Disease in Mice. Infection and Immunity. PMID 30249744 DOI: 10.1128/IAI.00533-18  0.168
2014 Garcia MN, Hotez PJ, Murray KO. Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasites & Vectors. 7: 311. PMID 24996479 DOI: 10.1186/1756-3305-7-311  0.168
2020 Tyungu DL, McCormick D, Lau CL, Chang M, Murphy JR, Hotez PJ, Mejia R, Pollack H. Toxocara species environmental contamination of public spaces in New York City. Plos Neglected Tropical Diseases. 14: e0008249. PMID 32369482 DOI: 10.1371/journal.pntd.0008249  0.168
2014 Hotez PJ. The NTDs and vaccine diplomacy in latin America: opportunities for united states foreign policy. Plos Neglected Tropical Diseases. 8: e2922. PMID 25255437 DOI: 10.1371/journal.pntd.0002922  0.167
2023 McKim S, Kopystynsky K, Wolf N, Akbar FA, Bottazzi ME, Hotez PJ, Mejia R. Environmental detection of parasites in the marginalized Paiute reservations compared to a nearby area. Medrxiv : the Preprint Server For Health Sciences. PMID 37961205 DOI: 10.1101/2023.10.24.23297407  0.167
2024 McKim S, Kopystynsky K, Wolf N, Akbar FA, Bottazzi ME, Hotez PJ, Mejia R. Environmental Detection of Parasites in the Marginalized Paiute Reservations Compared to a Nearby Area. The American Journal of Tropical Medicine and Hygiene. 110: 457-459. PMID 38350146 DOI: 10.4269/ajtmh.23-0712  0.164
2014 Garcia MN, Woc-Colburn L, Rossmann SN, Townsend RL, Stramer SL, Bravo M, Kamel H, Beddard R, Townsend M, Oldham R, Bottazzi ME, Hotez PJ, Murray KO. Trypanosoma cruzi screening in Texas blood donors, 2008-2012. Epidemiology and Infection. 1-4. PMID 25170765 DOI: 10.1017/S0950268814002234  0.164
2011 Hotez PJ. New antipoverty drugs, vaccines, and diagnostics: a research agenda for the US President's Global Health Initiative (GHI). Plos Neglected Tropical Diseases. 5: e1133. PMID 21655348 DOI: 10.1371/journal.pntd.0001133  0.164
2021 Rostami A, Riahi SM, Abdollahzadeh Sagha S, Taghipour A, Sepidarkish M, Mohammadnia-Afrouzi M, Ebrahimpour S, Hotez PJ, Gamble R, Gasser RB. Seroprevalence Estimates of Latent and Acute Infections in HIV People-Call for Action in Underprivileged Communities. Microorganisms. 9. PMID 34683355 DOI: 10.3390/microorganisms9102034  0.163
2017 Pollet J, Versteeg L, Rezende W, Strych U, Gusovsky F, Hotez PJ, Bottazzi ME. A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations. Vaccine. PMID 28190745 DOI: 10.1016/j.vaccine.2017.01.077  0.16
2022 Vilches TN, Sah P, Moghadas SM, Shoukat A, Fitzpatrick MC, Hotez PJ, Schneider EC, Galvani AP. COVID-19 hospitalizations and deaths averted under an accelerated vaccination program in northeastern and southern regions of the USA. Lancet Regional Health. Americas. 6: 100147. PMID 34977848 DOI: 10.1016/j.lana.2021.100147  0.16
2020 Hotez PJ. Anti-science extremism in America: escalating and globalizing. Microbes and Infection. PMID 32961275 DOI: 10.1016/j.micinf.2020.09.005  0.16
2015 Garcia MN, Woc-Colburn L, Aguilar D, Hotez PJ, Murray KO. Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States. Plos Neglected Tropical Diseases. 9: e0003981. PMID 26540273 DOI: 10.1371/Journal.Pntd.0003981  0.159
2023 Liu Z, Ulrich vonBargen R, Kendricks AL, Wheeler K, Leão AC, Sankaranarayanan K, Dean DA, Kane SS, Hossain E, Pollet J, Bottazzi ME, Hotez PJ, Jones KM, McCall LI. Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease. Nature Communications. 14: 6769. PMID 37880260 DOI: 10.1038/s41467-023-42247-w  0.159
2021 Blake A, Hotez PJ, Israeli A, Chinitz D. Lessons from an Ally: Learning from Israel to Vaccinate the American People. Microbes and Infection. 104796. PMID 33577990 DOI: 10.1016/j.micinf.2021.104796  0.157
2017 Brown EL, Gunter S, Jones KM, Seid C, Essigmann HT, Bottazzi ME, Hotez PJ, Zhan B, Strych U. Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis. The Journal of Parasitology. PMID 28581897 DOI: 10.1645/17-7  0.157
2014 Hotez PJ, Alvarado M, Basáñez MG, Bolliger I, Bourne R, Boussinesq M, Brooker SJ, Brown AS, Buckle G, Budke CM, Carabin H, Coffeng LE, Fèvre EM, Fürst T, Halasa YA, et al. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. Plos Neglected Tropical Diseases. 8: e2865. PMID 25058013 DOI: 10.1371/Journal.Pntd.0002865  0.153
2019 Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America. Expert Review of Anti-Infective Therapy. 1-13. PMID 30712412 DOI: 10.1080/14787210.2019.1577731  0.152
2013 Hotez PJ. NTDs V.2.0: "blue marble health"--neglected tropical disease control and elimination in a shifting health policy landscape. Plos Neglected Tropical Diseases. 7: e2570. PMID 24278496 DOI: 10.1371/journal.pntd.0002570  0.152
2009 Musgrove P, Hotez PJ. Turning neglected tropical diseases into forgotten maladies. Health Affairs (Project Hope). 28: 1691-706. PMID 19887410 DOI: 10.1377/hlthaff.28.6.1691  0.152
2018 Cromwell EA, Roy S, Sankara DP, Weiss A, Stanaway J, Goldberg E, Pigott DM, Larson H, Vollset SE, Krohn K, Foreman K, Hotez P, Bhutta Z, Bekele BB, Edessa D, et al. Slaying little dragons: the impact of the Guinea Worm Eradication Program on dracunculiasis disability averted from 1990 to 2016. Gates Open Research. 2: 30. PMID 30234196 DOI: 10.12688/gatesopenres.12827.1  0.148
2023 Liu Z, Ulrich R, Kendricks AL, Wheeler K, Leão AC, Pollet J, Bottazzi ME, Hotez P, Gusovsky F, Jones KM, McCall LI. Localized cardiac metabolic trajectories and post-infectious metabolic sequelae in experimental Chagas disease. Research Square. PMID 36711878 DOI: 10.21203/rs.3.rs-2497474/v1  0.147
2013 Sanghvi MM, Hotez PJ, Fenwick A. Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 165-8. PMID 23295048 DOI: 10.1111/liv.12052  0.147
2019 Parra-Henao G, Oliveros H, Hotez PJ, Motoa G, Franco-Paredes C, Henao-Martínez AF. In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia. The American Journal of Tropical Medicine and Hygiene. PMID 31264558 DOI: 10.4269/ajtmh.19-0110  0.142
2015 Murray KO, Fischer RS, Chavarria D, Duttmann C, Garcia MN, Gorchakov R, Hotez PJ, Jiron W, Leibler JH, Lopez JE, Mandayam S, Marin A, Sheleby J. Mesoamerican nephropathy: A neglected tropical disease with an infectious etiology? Microbes and Infection / Institut Pasteur. PMID 26320026 DOI: 10.1016/J.Micinf.2015.08.005  0.142
1982 Bogucki MS, Onodera M, Rosen NL, Lifter J, Hotez PJ, Konigsberg WH, Richards FF. Trypanosoma congolense: surface glycoproteins of two early bloodstream variants. III. Immunochemical characterization. Experimental Parasitology. 53: 1-10. PMID 7056338 DOI: 10.1016/0014-4894(82)90086-8  0.14
2024 Rasmussen AL, Gronvall GK, Lowen AC, Goodrum F, Alwine J, Andersen KG, Anthony SJ, Baines J, Banerjee A, Broadbent AJ, Brooke CB, Campos SK, Caposio P, Casadevall A, Chan GC, ... ... Hotez PJ, et al. Virology-the path forward. Journal of Virology. 98: e0179123. PMID 38168672 DOI: 10.1128/jvi.01791-23  0.139
2019 Hotez PJ. Linking Tropical Infections to Hypertension: New Comorbid Disease Paradigms in Our Era of "Blue Marble Health". Journal of the American Heart Association. 8: e03984. PMID 30879371 DOI: 10.1161/JAHA.119.012313  0.139
2003 Zhu XP, Yang J, Yang YP, Boireau P, Zhan B, Feng JJ, Hotez P. [Prokaryotic expression and characterization of an antigenic gene of adult Trichinella spiralis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 21: 16-9. PMID 12884582  0.139
2013 Keenan JD, Hotez PJ, Amza A, Stoller NE, Gaynor BD, Porco TC, Lietman TM. Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. Plos Neglected Tropical Diseases. 7: e2562. PMID 24340111 DOI: 10.1371/journal.pntd.0002562  0.137
2015 Turkeltaub JA, McCarty TR, Hotez PJ. The intestinal protozoa: emerging impact on global health and development. Current Opinion in Gastroenterology. 31: 38-44. PMID 25394233 DOI: 10.1097/MOG.0000000000000135  0.136
2014 Lee RM, Moore LB, Bottazzi ME, Hotez PJ. Toxocariasis in North America: a systematic review. Plos Neglected Tropical Diseases. 8: e3116. PMID 25166906 DOI: 10.1371/journal.pntd.0003116  0.136
2008 Hotez PJ, Molyneux DH. Tropical anemia: one of Africa's great killers and a rationale for linking malaria and neglected tropical disease control to achieve a common goal. Plos Neglected Tropical Diseases. 2: e270. PMID 18665256 DOI: 10.1371/journal.pntd.0000270  0.136
2004 Hotez PJ, Remme JH, Buss P, Alleyne G, Morel C, Breman JG. Combating tropical infectious diseases: report of the Disease Control Priorities in Developing Countries Project. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 38: 871-8. PMID 14999633 DOI: 10.1086/382077  0.133
2021 Hoffman KA, Villar MJ, Poveda C, Bottazzi ME, Hotez PJ, Tweardy DJ, Jones KM. Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Frontiers in Cellular and Infection Microbiology. 11: 708325. PMID 34504808 DOI: 10.3389/fcimb.2021.708325  0.132
2012 Hotez PJ, Aksoy S. Now we are six. Plos Neglected Tropical Diseases. 6: e1862. PMID 23145194 DOI: 10.1371/Journal.Pntd.0001862  0.131
2021 Talavera-López C, Messenger LA, Lewis MD, Yeo M, Reis-Cunha JL, Matos GM, Bartholomeu DC, Calzada JE, Saldaña A, Ramírez JD, Guhl F, Ocaña-Mayorga S, Costales JA, Gorchakov R, Jones K, ... ... Hotez PJ, et al. Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, . Frontiers in Cellular and Infection Microbiology. 11: 614665. PMID 33747978 DOI: 10.3389/fcimb.2021.614665  0.131
2014 Nguyen HM, Chhabra S, Chang SC, Huq RU, Tanner MR, Londono LM, Gindin M, Hotez PJ, Mohanty B, Iadonato SP, Gutman GA, Beeton C, Pennington MW, Norton RS, Chandy KG. Kv1.3-Blocking Peptides from Parasitic Worms Exhibit Immunomodulatory Function Biophysical Journal. 106: 739a. DOI: 10.1016/J.Bpj.2013.11.4073  0.131
2019 Armstrong PB, Selzer PM, Ahlborg N, Morehead K, Perregaux M, Komuniecki P, Komuniecki R, Srimal S, Hotez PJ. Identification and Partial Characterization of an Extracorporeal Protease Activity Secreted by the Triclad Turbellarid Worm, Bdelloura candida. The Biological Bulletin. 185: 326. PMID 27768428 DOI: 10.1086/BBLv185n2p326  0.13
2024 Cárdenas-Guerra RE, Montes-Flores O, Nava-Pintor EE, Reséndiz-Cardiel G, Flores-Pucheta CI, Rodríguez-Gavaldón YI, Arroyo R, Bottazzi ME, Hotez PJ, Ortega-López J. Chagasin from Trypanosoma cruzi as a molecular scaffold to express epitopes of TSA-1 as soluble recombinant chimeras. Protein Expression and Purification. 218: 106458. PMID 38423156 DOI: 10.1016/j.pep.2024.106458  0.129
2001 Wen LY, Hotez PJ. [Studies on immunological reaction of the antiserum of recombinant secreted protein from Ancylostoma caninum]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases. 19: 166-8. PMID 12571945  0.128
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