Donald Howard Rubin, M.D. - Publications

Affiliations: 
1992-2017 Medicine, Microbiology & Immunology Vanderbilt University Medical Center, Nashville, TN, United States 
Area:
virus, bacterial toxin, genomics, genetics

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cheng F, Murray JL, Rubin DH. Drug Repurposing: New Treatments for Zika Virus Infection? Trends in Molecular Medicine. PMID 27692879 DOI: 10.1016/J.Molmed.2016.09.006  0.392
2016 Cheng F, Murray JL, Zhao J, Sheng J, Zhao Z, Rubin DH. Systems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional Mutagenesis. Plos Computational Biology. 12: e1005074. PMID 27632082 DOI: 10.1371/Journal.Pcbi.1005074  0.366
2015 LaFrance ME, Farrow MA, Chandrasekaran R, Sheng J, Rubin DH, Lacy DB. Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 112: 7073-8. PMID 26038560 DOI: 10.1073/Pnas.1500791112  0.417
2014 Murray JL, Sheng J, Rubin DH. A role for H/ACA and C/D small nucleolar RNAs in viral replication. Molecular Biotechnology. 56: 429-37. PMID 24477674 DOI: 10.1007/S12033-013-9730-0  0.439
2014 Radin JN, González-Rivera C, Frick-Cheng AE, Sheng J, Gaddy JA, Rubin DH, Algood HM, McClain MS, Cover TL. Role of connexin 43 in Helicobacter pylori VacA-induced cell death. Infection and Immunity. 82: 423-32. PMID 24191302 DOI: 10.1128/Iai.00827-13  0.377
2012 Fennessey CM, Sheng J, Rubin DH, McClain MS. Oligomerization of Clostridium perfringens epsilon toxin is dependent upon caveolins 1 and 2. Plos One. 7: e46866. PMID 23056496 DOI: 10.1371/Journal.Pone.0046866  0.372
2012 Dziuba N, Ferguson MR, O'Brien WA, Sanchez A, Prussia AJ, McDonald NJ, Friedrich BM, Li G, Shaw MW, Sheng J, Hodge TW, Rubin DH, Murray JL. Identification of cellular proteins required for replication of human immunodeficiency virus type 1. Aids Research and Human Retroviruses. 28: 1329-39. PMID 22404213 DOI: 10.1089/Aid.2011.0358  0.401
2012 Murray JL, McDonald NJ, Sheng J, Shaw MW, Hodge TW, Rubin DH, O'Brien WA, Smee DF. Inhibition of influenza a virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis Antiviral Chemistry and Chemotherapy. 22: 205-215. PMID 22374988 DOI: 10.3851/Imp2080  0.362
2011 Friedrich BM, Murray JL, Li G, Sheng J, Hodge TW, Rubin DH, O'Brien WA, Ferguson MR. A functional role for ADAM10 in human immunodeficiency virus type-1 replication. Retrovirology. 8: 32. PMID 21569301 DOI: 10.1186/1742-4690-8-32  0.461
2011 Ivie SE, Fennessey CM, Sheng J, Rubin DH, McClain MS. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin. Plos One. 6: e17787. PMID 21412435 DOI: 10.1371/Journal.Pone.0017787  0.388
2006 Rubin DH, Ruley HE. Cellular genetics of host susceptibility and resistance to virus infection. Critical Reviews in Eukaryotic Gene Expression. 16: 155-70. PMID 16749895 DOI: 10.1615/Critreveukargeneexpr.V16.I2.40  0.413
2005 Murray JL, Mavrakis M, McDonald NJ, Yilla M, Sheng J, Bellini WJ, Zhao L, Le Doux JM, Shaw MW, Luo CC, Lippincott-Schwartz J, Sanchez A, Rubin DH, Hodge TW. Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus Journal of Virology. 79: 11742-11751. PMID 16140752 DOI: 10.1128/Jvi.79.18.11742-11751.2005  0.373
2004 Organ EL, Sheng J, Ruley HE, Rubin DH. Discovery of mammalian genes that participate in virus infection. Bmc Cell Biology. 5: 41. PMID 15522117 DOI: 10.1186/1471-2121-5-41  0.458
2004 Sheng J, Organ EL, Hao C, Wells KS, Ruley HE, Rubin DH. Mutations in the IGF-II pathway that confer resistance to lytic reovirus infection. Bmc Cell Biology. 5: 32. PMID 15333144 DOI: 10.1186/1471-2121-5-32  0.441
2004 Organ EL, Nalbantyan CD, Nanney LB, Woodward SC, Sheng J, Dubois RN, Price J, Sutcliffe M, Coffey RJ, Rubin DH. Effects of transforming growth factor-alpha (TGF-alpha) in vitro and in vivo on reovirus replication. Dna and Cell Biology. 23: 430-41. PMID 15294092 DOI: 10.1089/1044549041474751  0.411
2001 Rubin DH. Mucosal T cell response to reovirus Immunologic Research. 23: 229-234. PMID 11444387 DOI: 10.1385/Ir:23:2-3:229  0.427
1999 Saragovi HU, Rebai N, Di Guglielmo GM, Macleod R, Sheng J, Rubin DH, Greene MI. A G1 cell cycle arrest induced by ligands of the reovirus type 3 receptor is secondary to inactivation of p21ras and mitogen-activated protein kinase. Dna and Cell Biology. 18: 763-70. PMID 10541435 DOI: 10.1089/104454999314908  0.337
1999 Mora AL, Chen D, Boothby M, Rubin DH. Lineage-specific differences among CD8+ T cells in their dependence of NF-kappa B/Rel signaling. European Journal of Immunology. 29: 2968-80. PMID 10508271 DOI: 10.1002/(Sici)1521-4141(199909)29:09<2968::Aid-Immu2968>3.0.Co;2-X  0.306
1998 Major AS, Rubin DH, Cuff CF. Mucosal immunity to reovirus infection Current Topics in Microbiology and Immunology. 233: 163-177. PMID 9599937 DOI: 10.1007/978-3-642-72095-6_9  0.389
1998 Organ EL, Rubin DH. Pathogenesis of reovirus gastrointestinal and hepatobiliary disease. Current Topics in Microbiology and Immunology. 233: 67-83. PMID 9599932 DOI: 10.1007/978-3-642-72095-6_4  0.39
1997 Chen D, Lee F, Cebra JJ, Rubin DH. Predominant T-cell receptor Vbeta usage of intraepithelial lymphocytes during the immune response to enteric reovirus infection. Journal of Virology. 71: 3431-6. PMID 9094613 DOI: 10.1128/Jvi.71.5.3431-3436.1997  0.385
1995 Taterka J, Cebra JJ, Rubin DH. Characterization of cytotoxic cells from reovirus-infected SCID mice: activated cells express natural killer- and lymphokine-activated killer-like activity but fail to clear infection. Journal of Virology. 69: 3910-4. PMID 7745745 DOI: 10.1128/Jvi.69.6.3910-3914.1995  0.479
1994 Hooper DC, Rubin DH, Cebra JJ. Spontaneous proliferation of Peyer's patch cells in vitro. International Immunology. 6: 873-80. PMID 8086375 DOI: 10.1093/Intimm/6.6.873  0.39
1994 Taterka J, Sutcliffe M, Rubin DH. Selective reovirus infection of murine hepatocarcinoma cells during cell division. A model of viral liver infection. The Journal of Clinical Investigation. 94: 353-60. PMID 8040276 DOI: 10.1172/Jci117329  0.505
1993 Cuff CF, Cebra CK, Rubin DH, Cebra JJ. Developmental relationship between cytotoxic alpha/beta T cell receptor-positive intraepithelial lymphocytes and Peyer's patch lymphocytes. European Journal of Immunology. 23: 1333-9. PMID 8388798 DOI: 10.1002/Eji.1830230622  0.42
1992 Rubin DH, Weiner DB, Dworkin C, Greene MI, Maul GG, Williams WV. Receptor utilization by reovirus type 3: distinct binding sites on thymoma and fibroblast cell lines result in differential compartmentalization of virions. Microbial Pathogenesis. 12: 351-65. PMID 1501574 DOI: 10.1016/0882-4010(92)90098-9  0.452
1992 Taterka JA, Cuff CF, Rubin DH. Viral gastrointestinal infections Gastroenterology Clinics of North America. 21: 303-330. PMID 1324891  0.328
1992 Rubin DH, Wetzel JD, Williams WV, Cohen JA, Dworkin C, Dermody TS. Binding of type 3 reovirus by a domain of the σ1 protein important for hemagglutination leads to infection of murine erythroleukemia cells Journal of Clinical Investigation. 90: 2536-2542. PMID 1281838 DOI: 10.1172/Jci116147  0.611
1991 Cuff CF, Cebra CK, Lavi E, Molowitz EH, Rubin DH, Cebra JJ. Protection of neonatal mice from fatal reovirus infection by immune serum and gut derived lymphocytes. Advances in Experimental Medicine and Biology. 310: 307-15. PMID 1667070 DOI: 10.1007/978-1-4615-3838-7_40  0.38
1991 Cebra JJ, Cuff CF, Rubin DH. Relationship between alpha/beta T cell receptor/CD8+ precursors for cytotoxic T lymphocytes in the murine Peyer's patches and the intraepithelial compartment probed by oral infection with reovirus. Immunologic Research. 10: 321-3. PMID 1659604 DOI: 10.1007/Bf02919715  0.343
1990 Piccoli DA, Witzleben CL, Guico CJ, Morrison A, Rubin DH. Synergism between hepatic injuries and a nonhepatotropic reovirus in mice. Enhanced hepatic infection and death. The Journal of Clinical Investigation. 86: 1038-45. PMID 2170443 DOI: 10.1172/Jci114806  0.431
1990 Rubin DH, Morrison AH, Witzleben CL, Guico CJ, Piccoli DA. Site of reovirus replication in liver is determined by the type of hepatocellular insult. Journal of Virology. 64: 4593-7. PMID 2166834 DOI: 10.1128/Jvi.64.9.4593-4597.1990  0.338
1990 London SD, Cebra-Thomas JA, Rubin DH, Cebra JJ. CD8 lymphocyte subpopulations in Peyer's patches induced by reovirus serotype 1 infection. Journal of Immunology (Baltimore, Md. : 1950). 144: 3187-94. PMID 2157763  0.31
1990 George A, Kost SI, Witzleben CL, Cebra JJ, Rubin DH. Reovirus-induced liver disease in severe combined immunodeficient (SCID) mice. A model for the study of viral infection, pathogenesis, and clearance. The Journal of Experimental Medicine. 171: 929-34. PMID 2155280 DOI: 10.1084/Jem.171.3.929  0.437
1990 Cuff CF, Lavi E, Cebra CK, Cebra JJ, Rubin DH. Passive immunity to fatal reovirus serotype 3-induced meningoencephalitis mediated by both secretory and transplacental factors in neonatal mice. Journal of Virology. 64: 1256-63. PMID 2154608 DOI: 10.1128/Jvi.64.3.1256-1263.1990  0.412
1989 London SD, Cebra JJ, Rubin DH. Intraepithelial lymphocytes contain virus-specific, MHC-restricted cytotoxic cell precursors after gut mucosal immunization with reovirus serotype 1/Lang. Regional Immunology. 2: 98-102. PMID 2577122  0.379
1989 Cebra JJ, Cebra-Thomas JA, Cuff CF, George A, Kost SI, London SD, Rubin DH. Reoviruses as probes of the gut mucosal T cell population. Immunological Investigations. 18: 545-58. PMID 2543626 DOI: 10.3109/08820138909112262  0.465
1989 London SD, Cebra JJ, Rubin DH. The reovirus-specific cytotoxic T cell response is not restricted to serotypically unique epitopes associated with the virus hemagglutinin. Microbial Pathogenesis. 6: 43-50. PMID 2471913 DOI: 10.1016/0882-4010(89)90006-5  0.492
1988 Weiner DB, Girard K, Williams WV, McPhillips T, Rubin DH. Reovirus type 1 and type 3 differ in their binding to isolated intestinal epithelial cells. Microbial Pathogenesis. 5: 29-40. PMID 3072462 DOI: 10.1016/0882-4010(88)90078-2  0.408
1988 Kaljot KT, Shaw RD, Rubin DH, Greenberg HB. Infectious rotavirus enters cells by direct cell membrane penetration, not by endocytosis. Journal of Virology. 62: 1136-44. PMID 2831376 DOI: 10.1128/Jvi.62.4.1136-1144.1988  0.471
1988 Williams WV, Guy HR, Rubin DH, Robey F, Myers JN, Kieber-Emmons T, Weiner DB, Greene MI. Sequences of the cell-attachment sites of reovirus type 3 and its anti-idiotypic/antireceptor antibody: modeling of their three-dimensional structures. Proceedings of the National Academy of Sciences of the United States of America. 85: 6488-92. PMID 2457914 DOI: 10.1073/Pnas.85.17.6488  0.325
1987 Rubin DH. Reovirus serotype 1 binds to the basolateral membrane of intestinal epithelial cells Microbial Pathogenesis. 3: 215-219. PMID 3504220 DOI: 10.1016/0882-4010(87)90098-2  0.314
1987 Rubin DH, Costello T, Witzleben CL, Greene MI. Transport of infectious reovirus into bile: class II major histocompatibility antigen-bearing cells determine reovirus transport. Journal of Virology. 61: 3222-6. PMID 3476756 DOI: 10.1128/Jvi.61.10.3222-3226.1987  0.394
1987 London SD, Rubin DH, Cebra JJ. Gut mucosal immunization with reovirus serotype 1/L stimulates virus-specific cytotoxic T cell precursors as well as IgA memory cells in Peyer's patches. The Journal of Experimental Medicine. 165: 830-47. PMID 2950199 DOI: 10.1084/Jem.165.3.830  0.432
1987 London SD, Rubin DH, Cebra JJ. Murine Peyer's patches are capable of generating a cytotoxic T cell (CTL) response to nominal antigens. Advances in Experimental Medicine and Biology. 216: 267-78. PMID 2891243 DOI: 10.1007/978-1-4684-5344-7_31  0.39
1986 Rubin DH, Eaton MA, Costello T. Reovirus type 1 is secreted into the bile. Journal of Virology. 60: 726-8. PMID 3022004 DOI: 10.1128/Jvi.60.2.726-728.1986  0.413
1986 Rubin DH, Eaton MA, Anderson AO. Reovirus infection in adult mice: the virus hemagglutinin determines the site of intestinal disease Microbial Pathogenesis. 1: 79-87. PMID 2854595 DOI: 10.1016/0882-4010(86)90034-3  0.419
1985 Anderson AO, Rubin DH. Effect of Avridine on enteric antigen uptake and mucosal immunity to reovirus (1/Lang). Advances in Experimental Medicine and Biology. 186: 579-90. PMID 4050592 DOI: 10.1007/978-1-4613-2463-8_71  0.333
1985 Rubin DH, Kornstein MJ, Anderson AO. Reovirus serotype 1 intestinal infection: a novel replicative cycle with ileal disease. Journal of Virology. 53: 391-8. PMID 2982027 DOI: 10.1128/Jvi.53.2.391-398.1985  0.481
1983 Abramczuk J, Vorbrodt A, Rubin DH, Fields BN, Koprowski H. Interactions of preimplantation mouse embryos with reovirus serotypes 1 and 3. Infection and Immunity. 42: 301-7. PMID 6311748 DOI: 10.1128/Iai.42.1.301-307.1983  0.579
1982 Hrdy DB, Rubin DH, Fields BN. Molecular basis of reovirus neurovirulence: role of the M2 gene in avirulence. Proceedings of the National Academy of Sciences of the United States of America. 79: 1298-302. PMID 6951176 DOI: 10.1073/Pnas.79.4.1298  0.59
1981 Wolf JL, Rubin DH, Finberg R, Kauffman RS, Sharpe AH, Trier JS, Fields BN. Intestinal M cells: A pathway for entry of reovirus into the host Science. 212: 471-472. PMID 6259737 DOI: 10.1126/Science.6259737  0.584
1980 Rubin DH, Fields BN. Molecular basis of reovirus virulence. Role of the M2 gene Journal of Experimental Medicine. 152: 853-868. PMID 7420022 DOI: 10.1084/Jem.152.4.853  0.57
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