Bernhard Ryffel - Publications

Affiliations: 
Univ. of New Orleans, New Orleans, LA, United States 
Area:
PbA, Type I IFN, Interleukin-22, HDM, NLRP3, Caspase-1, IL-33, PIM, Tlr2, Flagellin

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nascimento M, Gombault A, Lacerda-Queiroz N, Panek C, Savigny F, Sbeity M, Bourinet M, Le Bert M, Riteau N, Ryffel B, Quesniaux VFJ, Couillin I. Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice. Scientific Reports. 9: 14848. PMID 31619733 DOI: 10.1038/s41598-019-51427-y  0.56
2019 Sokolowska M, Quesniaux VFJ, Akdis CA, Chung KF, Ryffel B, Togbe D. Acute Respiratory Barrier Disruption by Ozone Exposure in Mice. Frontiers in Immunology. 10: 2169. PMID 31608051 DOI: 10.3389/fimmu.2019.02169  0.56
2019 Benmerzoug S, Ryffel B, Togbe D, Quesniaux VFJ. Self-DNA Sensing in Lung Inflammatory Diseases. Trends in Immunology. PMID 31262653 DOI: 10.1016/j.it.2019.06.001  0.56
2019 Darby MG, Chetty A, Mrjden D, Rolot M, Smith K, Mackowiak C, Sedda D, Nyangahu D, Jaspan H, Toellner KM, Waisman A, Quesniaux V, Ryffel B, Cunningham AF, Dewals BG, et al. Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring. Science Advances. 5: eaav3058. PMID 31236458 DOI: 10.1126/sciadv.aav3058  0.56
2019 Benmerzoug S, Bounab B, Rose S, Gosset D, Biet F, Cochard T, Xavier A, Rouxel N, Fauconnier L, Horsnell WGC, Ryffel B, Togbe D, Quesniaux VFJ. Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity. Cell Reports. 27: 2649-2664.e5. PMID 31141689 DOI: 10.1016/j.celrep.2019.04.110  0.56
2019 Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG. Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression. Frontiers in Immunology. 10: 702. PMID 31057534 DOI: 10.3389/fimmu.2019.00702  0.56
2019 Chavez-Galan L, Vesin D, Blaser G, Uysal H, Benmerzoug S, Rose S, Ryffel B, Quesniaux VFJ, Garcia I. Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection. Scientific Reports. 9: 5297. PMID 30923339 DOI: 10.1038/s41598-019-41629-9  0.56
2018 Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, ... ... Ryffel B, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nature Communications. 9: 5338. PMID 30559449 DOI: 10.1038/s41467-018-07750-5  0.56
2018 Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, ... ... Ryffel B, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nature Communications. 9: 5226. PMID 30523277 DOI: 10.1038/s41467-018-07425-1  0.56
2018 Oldenhove G, Boucquey E, Taquin A, Acolty V, Bonetti L, Ryffel B, Le Bert M, Englebert K, Boon L, Moser M. PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity. Cell Reports. 25: 2053-2060.e4. PMID 30463004 DOI: 10.1016/j.celrep.2018.10.091  0.44
2018 Marques RE, Besnard AG, Maillet I, Fagundes CT, Souza DG, Ryffel B, Teixeira MM, Liew FY, Guabiraba R. IL-33 contributes to disease severity in Dengue virus infection in mice. Immunology. PMID 30098206 DOI: 10.1111/imm.12988  0.56
2018 Araujo AM, Antunes MM, Mattos MS, Diniz AB, Alvarenga DM, Nakagaki BN, Carvalho É, Lacerda VAS, Carvalho-Gontijo R, Goulart J, Mafra K, Freitas-Lopes MA, Oliveira HMC, Dutra CM, David BA, ... ... Ryffel B, et al. Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose. Cells. 7. PMID 30060463 DOI: 10.3390/cells7080088  0.56
2018 Secher T, Maillet I, Mackowiak C, Le Bérichel J, Philippeau A, Panek C, Boury M, Oswald E, Saoudi A, Erard F, Le Bert M, Quesniaux V, Couturier-Maillard A, Ryffel B. The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice. Scientific Reports. 8: 11245. PMID 30050168 DOI: 10.1038/s41598-018-29689-9  0.56
2018 Michaudel C, Fauconnier L, Julé Y, Ryffel B. Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice. Scientific Reports. 8: 10611. PMID 30006538 DOI: 10.1038/s41598-018-28261-9  0.56
2018 Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I. The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Frontiers in Immunology. 9: 1476. PMID 29988569 DOI: 10.3389/fimmu.2018.01476  0.56
2018 Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VF, Togbé D, Mergny JL, Cook-Moreau J, Cogné M. G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation. The Journal of Allergy and Clinical Immunology. PMID 29935221 DOI: 10.1016/j.jaci.2018.06.011  0.56
2018 Dosset M, Vargas TR, Lagrange A, Boidot R, Végran F, Roussey A, Chalmin F, Dondaine L, Paul C, Marie-Joseph EL, Martin F, Ryffel B, Borg C, Adotévi O, Ghiringhelli F, et al. PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer. Oncoimmunology. 7: e1433981. PMID 29872568 DOI: 10.1080/2162402X.2018.1433981  0.44
2018 Benmerzoug S, Marinho FV, Rose S, Mackowiak C, Gosset D, Sedda D, Poisson E, Uyttenhove C, Van Snick J, Jacobs M, Garcia I, Ryffel B, Quesniaux VFJ. GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection. Scientific Reports. 8: 8652. PMID 29872095 DOI: 10.1038/s41598-018-26984-3  0.56
2018 Michaudel C, Maillet I, Fauconnier L, Quesniaux V, Chung KF, Wiegman C, Peter D, Ryffel B. Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation. Frontiers in Immunology. 9: 916. PMID 29867931 DOI: 10.3389/fimmu.2018.00916  0.56
2018 Marinho FV, Benmerzoug S, Rose S, Campos PC, Marques JT, Báfica A, Barber G, Ryffel B, Oliveira SC, Quesniaux VFJ. The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection. Journal of Innate Immunity. 1-14. PMID 29791904 DOI: 10.1159/000488952  0.56
2018 Di Padova F, Quesniaux VFJ, Ryffel B. MyD88 as a therapeutic target for inflammatory lung diseases. Expert Opinion On Therapeutic Targets. 1-8. PMID 29658361 DOI: 10.1080/14728222.2018.1464139  0.56
2018 Michaudel C, Mackowiak C, Maillet I, Fauconnier L, Akdis C, Sokolowska M, Dreher A, Tan HT, Quesniaux VF, Ryffel B, Togbe D. Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by Interleukin-33. The Journal of Allergy and Clinical Immunology. PMID 29331644 DOI: 10.1016/j.jaci.2017.11.044  0.56
2017 Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, et al. Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nature Immunology. PMID 29255269 DOI: 10.1038/s41590-017-0013-y  0.56
2017 Belmellat N, Semerano L, Segueni N, Damotte D, Decker P, Ryffel B, Quesniaux V, Boissier MC, Assier E. Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection. Frontiers in Immunology. 8: 1533. PMID 29184553 DOI: 10.3389/fimmu.2017.01533  0.56
2017 Routy B, Le Chatelier E, Derosa L, Duong CPM, Alou MT, Daillère R, Fluckiger A, Messaoudene M, Rauber C, Roberti MP, Fidelle M, Flament C, Poirier-Colame V, Opolon P, Klein C, ... ... Ryffel B, et al. Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science (New York, N.Y.). PMID 29097494 DOI: 10.1126/science.aan3706  0.56
2017 Antunes MM, Araújo AM, Diniz AB, Pereira RVS, Alvarenga DM, David BA, Rocha RM, Lopes MAF, Marchesi SC, Nakagaki BN, Carvalho É, Marques PE, Ryffel B, Quesniaux V, Brito RG, et al. IL-33 signalling in liver immune cells enhances drug-induced liver injury and inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 29032512 DOI: 10.1007/s00011-017-1098-3  0.56
2017 Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, Mauny P, Lory R, Uttenhove C, van Snick J, Iwakura Y, di Padova F, Quesniaux V, Togbe D, Ryffel B. Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice. Clinical Science (London, England : 1979). 131: 2533-2548. PMID 29026003 DOI: 10.1042/CS20171034  0.56
2017 Francisco NM, Fang YM, Ding L, Feng S, Yang Y, Wu M, Jacobs M, Ryffel B, Huang X. Diagnostic accuracy of a selected signature gene set that discriminates active pulmonary tuberculosis and other pulmonary diseases. The Journal of Infection. PMID 28941629 DOI: 10.1016/j.jinf.2017.09.012  0.44
2017 Chavez-Galan L, Vesin D, Uysal H, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I. Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy. Frontiers in Immunology. 8: 999. PMID 28890718 DOI: 10.3389/fimmu.2017.00999  0.56
2017 Dos Santos JC, Grund LZ, Seibert CS, Marques EE, Soares AB, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Stingray venom activates IL-33 producing cardiomyocytes, but not mast cell, to promote acute neutrophil-mediated injury. Scientific Reports. 7: 7912. PMID 28801624 DOI: 10.1038/s41598-017-08395-y  0.56
2017 Marinho FV, Benmerzoug S, Oliveira SC, Ryffel B, Quesniaux VFJ. The Emerging Roles of STING in Bacterial Infections. Trends in Microbiology. PMID 28625530 DOI: 10.1016/j.tim.2017.05.008  0.4
2017 Reverchon F, Mortaud S, Sivoyon M, Maillet I, Laugeray A, Palomo J, Montécot C, Herzine A, Meme S, Meme W, Erard F, Ryffel B, Menuet A, Quesniaux VFJ. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. Plos Pathogens. 13: e1006322. PMID 28448579 DOI: 10.1371/journal.ppat.1006322  0.56
2017 Li C, Maillet I, Mackowiak C, Viala C, Di Padova F, Li M, Togbe D, Quesniaux V, Lai Y, Ryffel B. Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells. Cell Death & Disease. 8: e2735. PMID 28383552 DOI: 10.1038/cddis.2017.90  0.56
2017 Hsu NJ, Francisco NM, Keeton R, Allie N, Quesniaux VF, Ryffel B, Jacobs M. Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis. Frontiers in Immunology. 8: 180. PMID 28280495 DOI: 10.3389/fimmu.2017.00180  0.56
2017 Tan Z, Liu Q, Jiang R, Lv L, Shoto SS, Maillet I, Quesniaux V, Tang J, Zhang W, Sun B, Ryffel B. Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells. Cellular & Molecular Immunology. PMID 28194023 DOI: 10.1038/cmi.2016.63  0.56
2016 Grund LZ, Novaski I, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R. Autoimmunity. 1-16. PMID 28010135 DOI: 10.1080/08916934.2016.1261834  0.56
2016 Dambuza IM, Keeton R, Hsu NJ, Allie N, Quesniaux VF, Ryffel B, Jacobs M. Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation. Scientific Reports. 6: 39499. PMID 27995986 DOI: 10.1038/srep39499  0.56
2016 Segueni N, Tritto E, Bourigault ML, Rose S, Erard F, Le Bert M, Jacobs M, Di Padova F, Stiehl DP, Moulin P, Brees D, Chibout SD, Ryffel B, Kammüller M, Quesniaux VF. Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization. Scientific Reports. 6: 36923. PMID 27853279 DOI: 10.1038/srep36923  0.56
2016 Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, ... ... Ryffel B, et al. PKC theta controls ILC2 and Th2 responses to house dust mite allergen. The Journal of Allergy and Clinical Immunology. PMID 27746240 DOI: 10.1016/j.jaci.2016.08.044  0.56
2016 Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, Chenuet P, Guillou N, Le Bérichel J, Kisielow M, Flodby P, Borok Z, Crandall ED, Le Bert M, Quesniaux V, ... ... Ryffel B, et al. IL-1R1-MyD88 axis elicits papain-induced lung inflammation. European Journal of Immunology. PMID 27569535 DOI: 10.1002/eji.201646366  0.56
2016 Maillet I, Perche O, Pâris A, Richard O, Gombault A, Herzine A, Pichon J, Huaux F, Mortaud S, Ryffel B, Quesniaux V, Montecot-Dubourg C. Glufosinate aerogenic exposure induces glutamate and IL-1 receptors dependent lung inflammation. Clinical Science (London, England : 1979). PMID 27549113 DOI: 10.1042/CS20160530  0.56
2016 Chavez-Galan L, Vesin D, Segueni N, Prasad P, Buser-Llinares R, Blaser G, Pache JC, Ryffel B, Quesniaux VF, Garcia I. Tumor Necrosis Factor and Its Receptors Are Crucial to Control Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection in a Murine Model. The American Journal of Pathology. PMID 27456129 DOI: 10.1016/j.ajpath.2016.05.015  0.56
2016 Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S. Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension. The European Respiratory Journal. 48: 470-83. PMID 27418552 DOI: 10.1183/13993003.01448-2015  0.56
2016 Pietrocola F, Pol J, Vacchelli E, Rao S, Enot DP, Baracco EE, Levesque S, Castoldi F, Jacquelot N, Yamazaki T, Senovilla L, Marino G, Aranda F, Durand S, Sica V, ... ... Ryffel B, et al. Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell. 30: 147-60. PMID 27411589 DOI: 10.1016/j.ccell.2016.05.016  0.44
2016 Desoubeaux G, Reichert JM, Sleeman M, Reckamp KL, Ryffel B, Adamczewski JP, Sweeney TD, Vanbever R, Diot P, Owen CA, Page C, Lerondel S, Le Pape A, Heuze-Vourc'h N. Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France. Mabs. 0. PMID 27266390 DOI: 10.1080/19420862.2016.1196521  0.44
2016 Michaudel C, Couturier-Maillard A, Chenuet P, Maillet I, Mura C, Couillin I, Gombault A, Quesniaux VF, Huaux F, Ryffel B. Inflammasome, IL-1 and inflammation in ozone-induced lung injury. American Journal of Clinical and Experimental Immunology. 5: 33-40. PMID 27168953  0.56
2016 Lamas B, Richard ML, Leducq V, Pham HP, Michel ML, Da Costa G, Bridonneau C, Jegou S, Hoffmann TW, Natividad JM, Brot L, Taleb S, Couturier-Maillard A, Nion-Larmurier I, Merabtene F, ... ... Ryffel B, et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nature Medicine. PMID 27158904 DOI: 10.1038/nm.4102  0.56
2016 Cochez PM, Michiels C, Hendrickx E, Van Belle AB, Lemaire MM, Dauguet N, Warnier G, de Heusch M, Togbe D, Ryffel B, Coulie PG, Renauld JC, Dumoutier L. AhR modulates the IL-22-producing cell proliferation/recruitment in imiquimod-induced psoriasis mouse model. European Journal of Immunology. 46: 1449-59. PMID 27000947 DOI: 10.1002/eji.201546070  0.52
2016 Segueni N, Benmerzoug S, Rose S, Gauthier A, Bourigault ML, Reverchon F, Philippeau A, Erard F, Le Bert M, Bouscayrol H, Wachter T, Garcia I, Kollias G, Jacobs M, Ryffel B, et al. Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection. Scientific Reports. 6: 22454. PMID 26931771 DOI: 10.1038/srep22454  0.44
2016 Alcocer-Gómez E, Ulecia-Morón C, Marín-Aguilar F, Rybkina T, Casas-Barquero N, Ruiz-Cabello J, Ryffel B, Apetoh L, Ghiringhelli F, Bullón P, Sánchez-Alcazar JA, Carrión AM, Cordero MD. Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome. Molecular Neurobiology. 53: 4874-82. PMID 26362308 DOI: 10.1007/s12035-015-9408-7  0.44
2016 Bullón P, Alcocer-Gómez E, Carrión AM, Marín-Aguilar F, Garrido-Maraver J, Román-Malo L, Ruiz-Cabello J, Culic O, Ryffel B, Apetoh L, Ghiringhelli F, Battino M, Sánchez-Alcazar JA, Cordero MD. AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome. Antioxidants & Redox Signaling. 24: 157-70. PMID 26132721 DOI: 10.1089/ars.2014.6120  0.44
2015 Bruchard M, Rebé C, Derangère V, Togbé D, Ryffel B, Boidot R, Humblin E, Hamman A, Chalmin F, Berger H, Chevriaux A, Limagne E, Apetoh L, Végran F, Ghiringhelli F. Corrigendum: The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. Nature Immunology. 16: 1292. PMID 26580508 DOI: 10.1038/ni1215-1292a  0.44
2015 Amaral FA, Bastos LF, Oliveira TH, Dias AC, Oliveira VL, Tavares LD, Costa VV, Galvão I, Soriani FM, Szymkowski DE, Ryffel B, Souza DG, Teixeira MM. Transmembrane TNF-α is sufficient for articular inflammation and hypernociception in a mouse model of gout. European Journal of Immunology. PMID 26449770 DOI: 10.1002/eji.201545798  0.44
2015 Pinto LG, Talbot J, Peres RS, Franca RF, Ferreira SH, Ryffel B, Aves-Filho JC, Figueiredo F, Cunha TM, Cunha FQ. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy. 17: 235. PMID 26330334 DOI: 10.1186/s13075-015-0759-2  0.44
2015 Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26310268 DOI: 10.1096/fj.14-267146  0.44
2015 Rabeony H, Pohin M, Vasseur P, Petit-Paris I, Jégou JF, Favot L, Frouin E, Boutet MA, Blanchard F, Togbe D, Ryffel B, Bernard FX, Lecron JC, Morel F. IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome. European Journal of Immunology. 45: 2847-57. PMID 26147228 DOI: 10.1002/eji.201445215  0.44
2015 Francisco NM, Hsu NJ, Keeton R, Randall P, Sebesho B, Allie N, Govender D, Quesniaux V, Ryffel B, Kellaway L, Jacobs M. TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis. Journal of Neuroinflammation. 12: 125. PMID 26112704 DOI: 10.1186/s12974-015-0345-1  0.44
2015 Bruchard M, Rebé C, Derangère V, Togbé D, Ryffel B, Boidot R, Humblin E, Hamman A, Chalmin F, Berger H, Chevriaux A, Limagne E, Apetoh L, Végran F, Ghiringhelli F. The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. Nature Immunology. 16: 859-70. PMID 26098997 DOI: 10.1038/ni.3202  0.44
2015 Segueni N, Vigne S, Palmer G, Bourigault ML, Olleros ML, Vesin D, Garcia I, Ryffel B, Quesniaux VF, Gabay C. Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection. Plos One. 10: e0126058. PMID 25950182 DOI: 10.1371/journal.pone.0126058  0.56
2015 Randall PJ, Hsu NJ, Quesniaux V, Ryffel B, Jacobs M. Mycobacterium tuberculosis infection of the 'non-classical immune cell'. Immunology and Cell Biology. PMID 25801479 DOI: 10.1038/icb.2015.43  0.44
2015 Madouri F, Guillou N, Fauconnier L, Marchiol T, Rouxel N, Chenuet P, Ledru A, Apetoh L, Ghiringhelli F, Chamaillard M, Zheng SG, Trovero F, Quesniaux VF, Ryffel B, Togbe D. Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. Journal of Molecular Cell Biology. 7: 351-65. PMID 25714839 DOI: 10.1093/jmcb/mjv012  0.56
2015 Lopes AH, Talbot J, Silva RL, Lima JB, França RO, Verri WA, Mascarenhas DP, Ryffel B, Cunha FQ, Zamboni DS, Cunha TM. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain. 156: 451-9. PMID 25687541 DOI: 10.1097/01.j.pain.0000460322.72396.53  0.44
2015 Palomo J, Reverchon F, Piotet J, Besnard AG, Couturier-Maillard A, Maillet I, Tefit M, Erard F, Mazier D, Ryffel B, Quesniaux VF. Critical role of IL-33 receptor ST2 in experimental cerebral malaria development. European Journal of Immunology. 45: 1354-65. PMID 25682948 DOI: 10.1002/eji.201445206  0.56
2015 Besnard AG, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw TN, Couper KN, Ryffel B, Liew FY. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. Plos Pathogens. 11: e1004607. PMID 25659095 DOI: 10.1371/journal.ppat.1004607  0.52
2015 Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE. In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria. Plos Pathogens. 11: e1004598. PMID 25658925 DOI: 10.1371/journal.ppat.1004598  0.44
2015 François A, Gombault A, Villeret B, Alsaleh G, Fanny M, Gasse P, Adam SM, Crestani B, Sibilia J, Schneider P, Bahram S, Quesniaux V, Ryffel B, Wachsmann D, Gottenberg JE, et al. B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis. Journal of Autoimmunity. 56: 1-11. PMID 25441030 DOI: 10.1016/j.jaut.2014.08.003  0.56
2015 Huaux F, Lo Re S, Giordano G, Uwambayinema F, Devosse R, Yakoub Y, Panin N, Palmai-Pallag M, Rabolli V, Delos M, Marbaix E, Dauguet N, Couillin I, Ryffel B, Renauld JC, et al. IL-1α induces CD11b(low) alveolar macrophage proliferation and maturation during granuloma formation. The Journal of Pathology. 235: 698-709. PMID 25421226 DOI: 10.1002/path.4487  0.56
2015 Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS. Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection. The Journal of Infectious Diseases. 211: 1015-26. PMID 25274569 DOI: 10.1093/infdis/jiu531  0.44
2014 Palomo J, Marchiol T, Piotet J, Fauconnier L, Robinet M, Reverchon F, Le Bert M, Togbe D, Buijs-Offerman R, Stolarczyk M, Quesniaux VF, Scholte BJ, Ryffel B. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection. Plos One. 9: e114884. PMID 25500839 DOI: 10.1371/journal.pone.0114884  0.56
2014 Niedbala W, Besnard AG, Nascimento DC, Donate PB, Sonego F, Yip E, Guabiraba R, Chang HD, Fukada SY, Salmond RJ, Schmitt E, Bopp T, Ryffel B, Liew FY. Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nature Communications. 5: 4575. PMID 25099390 DOI: 10.1038/ncomms5575  0.44
2014 Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, et al. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proceedings of the National Academy of Sciences of the United States of America. 111: E3432-40. PMID 25099355 DOI: 10.1073/pnas.1408780111  0.44
2014 Végran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, Chalmin F, Rébé C, Dérangère V, Ryffel B, Kato M, Prévost-Blondel A, Ghiringhelli F, Apetoh L. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nature Immunology. 15: 758-66. PMID 24973819 DOI: 10.1038/ni.2925  0.44
2014 Arifa RD, Madeira MF, de Paula TP, Lima RL, Tavares LD, Menezes-Garcia Z, Fagundes CT, Rachid MA, Ryffel B, Zamboni DS, Teixeira MM, Souza DG. Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1β and IL-18 in mice. The American Journal of Pathology. 184: 2023-34. PMID 24952429 DOI: 10.1016/j.ajpath.2014.03.012  0.44
2014 Keeton R, Allie N, Dambuza I, Abel B, Hsu NJ, Sebesho B, Randall P, Burger P, Fick E, Quesniaux VF, Ryffel B, Jacobs M. Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis. The Journal of Clinical Investigation. 124: 1537-51. PMID 24569452 DOI: 10.1172/JCI45005  0.44
2014 Randall PJ, Hsu NJ, Lang D, Cooper S, Sebesho B, Allie N, Keeton R, Francisco NM, Salie S, Labuschagné A, Quesniaux V, Ryffel B, Kellaway L, Jacobs M. Neurons are host cells for Mycobacterium tuberculosis. Infection and Immunity. 82: 1880-90. PMID 24566619 DOI: 10.1128/IAI.00474-13  0.44
2014 Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. The Journal of Pharmacology and Experimental Therapeutics. 349: 209-20. PMID 24556663 DOI: 10.1124/jpet.113.208223  0.56
2014 Faure E, Mear JB, Faure K, Normand S, Couturier-Maillard A, Grandjean T, Balloy V, Ryffel B, Dessein R, Chignard M, Uyttenhove C, Guery B, Gosset P, Chamaillard M, Kipnis E. Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome. American Journal of Respiratory and Critical Care Medicine. 189: 799-811. PMID 24555512 DOI: 10.1164/rccm.201307-1358OC  0.56
2014 Chen M, Lin X, Liu Y, Li Q, Deng Y, Liu Z, Brand D, Guo Z, He X, Ryffel B, Zheng SG. The function of BAFF on T helper cells in autoimmunity. Cytokine & Growth Factor Reviews. 25: 301-5. PMID 24411564 DOI: 10.1016/j.cytogfr.2013.12.011  0.44
2014 Guabiraba R, Ryffel B. Dengue virus infection: current concepts in immune mechanisms and lessons from murine models. Immunology. 141: 143-56. PMID 24182427 DOI: 10.1111/imm.12188  0.32
2014 Almeida PE, Roque NR, Magalhães KG, Mattos KA, Teixeira L, Maya-Monteiro C, Almeida CJ, Castro-Faria-Neto HC, Ryffel B, Quesniaux VF, Bozza PT. Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection. Biochimica Et Biophysica Acta. 1841: 97-107. PMID 24120921 DOI: 10.1016/j.bbalip.2013.10.008  0.56
2014 Ma J, Liu Y, Li Y, Gu J, Liu J, Tang J, Wang J, Ryffel B, Shen Y, Brand D, Liu Z, Zheng SG. Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells. Journal of Leukocyte Biology. 95: 275-83. PMID 24082012 DOI: 10.1189/jlb.0513297  0.44
2014 Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, Wang J, Fan H, Shen Y, Ryffel B, Brand D, Quismorio F, Liu Z, Horwitz DA, Xu A, et al. Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. Journal of Molecular Cell Biology. 6: 81-92. PMID 23861553 DOI: 10.1093/jmcb/mjt026  0.44
2013 Bourigault ML, Segueni N, Rose S, Court N, Vacher R, Vasseur V, Erard F, Le Bert M, Garcia I, Iwakura Y, Jacobs M, Ryffel B, Quesniaux VF. Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG. Immunity, Inflammation and Disease. 1: 47-62. PMID 25400917 DOI: 10.1002/iid3.9  0.56
2013 Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, ... ... Ryffel B, et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (New York, N.Y.). 342: 971-6. PMID 24264990 DOI: 10.1126/science.1240537  0.44
2013 Secher T, Fas S, Fauconnier L, Mathieu M, Rutschi O, Ryffel B, Rudolf M. The anti-Pseudomonas aeruginosa antibody Panobacumab is efficacious on acute pneumonia in neutropenic mice and has additive effects with meropenem. Plos One. 8: e73396. PMID 24023870 DOI: 10.1371/journal.pone.0073396  0.44
2013 Besnard AG, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B. CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model. Journal of Leukocyte Biology. 94: 1317-23. PMID 23975892 DOI: 10.1189/jlb.0313140  0.56
2013 Villeret B, Brault L, Couturier-Maillard A, Robinet P, Vasseur V, Secher T, Dimier-Poisson I, Jacobs M, Zheng SG, Quesniaux VF, Ryffel B. Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice. American Journal of Clinical and Experimental Immunology. 2: 107-16. PMID 23885328  0.56
2013 Tan Z, Qian X, Jiang R, Liu Q, Wang Y, Chen C, Wang X, Ryffel B, Sun B. IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. Journal of Immunology (Baltimore, Md. : 1950). 191: 1835-44. PMID 23842754 DOI: 10.4049/jimmunol.1203013  0.44
2013 Palomo J, Fauconnier M, Coquard L, Gilles M, Meme S, Szeremeta F, Fick L, Franetich JF, Jacobs M, Togbe D, Beloeil JC, Mazier D, Ryffel B, Quesniaux VF. Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA. European Journal of Immunology. 43: 2683-95. PMID 23780878 DOI: 10.1002/eji.201343327  0.56
2013 Togbe D, Fauconnier L, Madouri F, Marchiol T, Chenuet P, Rouxel N, Ledru A, Erard F, Quesniaux V, Ryffel B. Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation. Isrn Allergy. 2013: 971036. PMID 23738146 DOI: 10.1155/2013/971036  0.56
2013 Garcia CC, Weston-Davies W, Russo RC, Tavares LP, Rachid MA, Alves-Filho JC, Machado AV, Ryffel B, Nunn MA, Teixeira MM. Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury. Plos One. 8: e64443. PMID 23696894 DOI: 10.1371/journal.pone.0064443  0.44
2013 Allie N, Grivennikov SI, Keeton R, Hsu NJ, Bourigault ML, Court N, Fremond C, Yeremeev V, Shebzukhov Y, Ryffel B, Nedospasov SA, Quesniaux VF, Jacobs M. Prominent role for T cell-derived tumour necrosis factor for sustained control of Mycobacterium tuberculosis infection. Scientific Reports. 3: 1809. PMID 23657146 DOI: 10.1038/srep01809  0.56
2013 Roversi P, Ryffel B, Togbe D, Maillet I, Teixeira M, Ahmat N, Paesen GC, Lissina O, Boland W, Ploss K, Caesar JJ, Leonhartsberger S, Lea SM, Nunn MA. Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury. The Journal of Biological Chemistry. 288: 18789-802. PMID 23625922 DOI: 10.1074/jbc.M112.420331  0.56
2013 Berger H, Végran F, Chikh M, Gilardi F, Ladoire S, Bugaut H, Mignot G, Chalmin F, Bruchard M, Derangère V, Chevriaux A, Rébé C, Ryffel B, Pot C, Hichami A, et al. SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth. Cancer Research. 73: 3578-90. PMID 23619236 DOI: 10.1158/0008-5472.CAN-12-4018  0.44
2013 Guabiraba R, Besnard AG, Marques RE, Maillet I, Fagundes CT, Conceição TM, Rust NM, Charreau S, Paris I, Lecron JC, Renauld JC, Quesniaux V, Da Poian AT, Arruda LB, Souza DG, ... Ryffel B, et al. IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection. European Journal of Immunology. 43: 1529-44. PMID 23505056 DOI: 10.1002/eji.201243229  0.56
2013 Chen M, Su W, Lin X, Guo Z, Wang J, Zhang Q, Brand D, Ryffel B, Huang J, Liu Z, He X, Le AD, Zheng SG. Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. Arthritis and Rheumatism. 65: 1181-93. PMID 23400582 DOI: 10.1002/art.37894  0.44
2013 Tan Z, Jiang R, Wang X, Wang Y, Lu L, Liu Q, Zheng SG, Sun B, Ryffel B. RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. Journal of Molecular Cell Biology. 5: 143-6. PMID 23362310 DOI: 10.1093/jmcb/mjs065  0.44
2013 Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, et al. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. The Journal of Clinical Investigation. 123: 700-11. PMID 23281400 DOI: 10.1172/JCI62236  0.56
2013 Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nature Medicine. 19: 57-64. PMID 23202296 DOI: 10.1038/nm.2999  0.44
2013 Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, ... ... Ryffel B, et al. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 62: 1714-23. PMID 23172891 DOI: 10.1136/gutjnl-2011-301785  0.44
2012 Schnyder-Candrian S, Maillet I, Le Bert M, Brault L, Jacobs M, Ryffel B, Schnyder B, Moser R. Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation. Journal of Allergy. 2012: 245909. PMID 23304174 DOI: 10.1155/2012/245909  0.56
2012 Sorgi CA, Rose S, Court N, Carlos D, Paula-Silva FW, Assis PA, Frantz FG, Ryffel B, Quesniaux V, Faccioli LH. GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands. Plos One. 7: e40523. PMID 22808181 DOI: 10.1371/journal.pone.0040523  0.44
2012 Xu W, Lan Q, Chen M, Chen H, Zhu N, Zhou X, Wang J, Fan H, Yan CS, Kuang JL, Warburton D, Togbe D, Ryffel B, Zheng SG, Shi W. Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. Plos One. 7: e40314. PMID 22792275 DOI: 10.1371/journal.pone.0040314  0.52
2012 Lan Q, Zhou X, Fan H, Chen M, Wang J, Ryffel B, Brand D, Ramalingam R, Kiela PR, Horwitz DA, Liu Z, Zheng SG. Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome. Journal of Molecular Cell Biology. 4: 409-19. PMID 22773728 DOI: 10.1093/jmcb/mjs040  0.44
2012 Su W, Fan H, Chen M, Wang J, Brand D, He X, Quesniaux V, Ryffel B, Zhu L, Liang D, Zheng SG. Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1. The Journal of Allergy and Clinical Immunology. 130: 444-52.e7. PMID 22738679 DOI: 10.1016/j.jaci.2012.05.011  0.56
2012 Chen M, Guo Z, Ju W, Ryffel B, He X, Zheng SG. The development and function of follicular helper T cells in immune responses. Cellular & Molecular Immunology. 9: 375-9. PMID 22659733 DOI: 10.1038/cmi.2012.18  0.44
2012 Kong N, Lan Q, Chen M, Wang J, Shi W, Horwitz DA, Quesniaux V, Ryffel B, Liu Z, Brand D, Zou H, Zheng SG. Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis and Rheumatism. 64: 2548-58. PMID 22605463 DOI: 10.1002/art.34513  0.44
2012 Chapman R, Shephard E, Stutz H, Douglass N, Sambandamurthy V, Garcia I, Ryffel B, Jacobs W, Williamson AL. Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells. Plos One. 7: e32769. PMID 22479338 DOI: 10.1371/journal.pone.0032769  0.44
2012 Chalmin F, Mignot G, Bruchard M, Chevriaux A, Végran F, Hichami A, Ladoire S, Derangère V, Vincent J, Masson D, Robson SC, Eberl G, Pallandre JR, Borg C, Ryffel B, et al. Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity. 36: 362-73. PMID 22406269 DOI: 10.1016/j.immuni.2011.12.019  0.44
2012 Fauconnier M, Palomo J, Bourigault ML, Meme S, Szeremeta F, Beloeil JC, Danneels A, Charron S, Rihet P, Ryffel B, Quesniaux VF. IL-12Rβ2 is essential for the development of experimental cerebral malaria. Journal of Immunology (Baltimore, Md. : 1950). 188: 1905-14. PMID 22238458 DOI: 10.4049/jimmunol.1101978  0.56
2012 Besnard AG, Togbe D, Couillin I, Tan Z, Zheng SG, Erard F, Le Bert M, Quesniaux V, Ryffel B. Inflammasome-IL-1-Th17 response in allergic lung inflammation. Journal of Molecular Cell Biology. 4: 3-10. PMID 22147847 DOI: 10.1093/jmcb/mjr042  0.56
2012 Lan Q, Fan H, Quesniaux V, Ryffel B, Liu Z, Zheng SG. Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? Journal of Molecular Cell Biology. 4: 22-8. PMID 22107826 DOI: 10.1093/jmcb/mjr039  0.56
2012 Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis and Rheumatism. 64: 474-84. PMID 21952942 DOI: 10.1002/art.33355  0.44
2011 Conforti-Andreoni C, Spreafico R, Qian HL, Riteau N, Ryffel B, Ricciardi-Castagnoli P, Mortellaro A. Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18. Journal of Immunology (Baltimore, Md. : 1950). 187: 5842-50. PMID 22058415 DOI: 10.4049/jimmunol.1101408  0.44
2011 Olagnier D, Lavergne RA, Meunier E, Lefèvre L, Dardenne C, Aubouy A, Benoit-Vical F, Ryffel B, Coste A, Berry A, Pipy B. Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria. Plos Pathogens. 7: e1002254. PMID 21949655 DOI: 10.1371/journal.ppat.1002254  0.44
2011 Lu L, Ma J, Li Z, Lan Q, Chen M, Liu Y, Xia Z, Wang J, Han Y, Shi W, Quesniaux V, Ryffel B, Brand D, Li B, Liu Z, et al. All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus. Plos One. 6: e24590. PMID 21931768 DOI: 10.1371/journal.pone.0024590  0.56
2011 Front S, Court N, Bourigault ML, Rose S, Ryffel B, Erard F, Quesniaux VF, Martin OR. Phosphatidyl myo-inositol mannosides mimics built on an acyclic or heterocyclic core: synthesis and anti-inflammatory properties. Chemmedchem. 6: 2081-93. PMID 21901834 DOI: 10.1002/cmdc.201100291  0.44
2011 Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, di Padova F, Fick L, Charron S, Lagente V, Eberl G, Le Bert M, Quesniaux VF, Huaux F, Leite-de-Moraes M, Ryffel B, et al. IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis. Plos One. 6: e23185. PMID 21858022 DOI: 10.1371/journal.pone.0023185  0.56
2011 Renneson J, Guabiraba R, Maillet I, Marques RE, Ivanov S, Fontaine J, Paget C, Quesniaux V, Faveeuw C, Ryffel B, Teixeira MM, Trottein F. A detrimental role for invariant natural killer T cells in the pathogenesis of experimental dengue virus infection. The American Journal of Pathology. 179: 1872-83. PMID 21843496 DOI: 10.1016/j.ajpath.2011.06.023  0.56
2011 Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B. IL-33-activated dendritic cells are critical for allergic airway inflammation. European Journal of Immunology. 41: 1675-86. PMID 21469105 DOI: 10.1002/eji.201041033  0.56
2011 Maillet I, Schnyder-Candrian S, Couillin I, Quesniaux VF, Erard F, Moser R, Fleury S, Kanda A, Dombrowicz D, Szymkowski DE, Ryffel B. Allergic lung inflammation is mediated by soluble tumor necrosis factor (TNF) and attenuated by dominant-negative TNF biologics. American Journal of Respiratory Cell and Molecular Biology. 45: 731-9. PMID 21297077 DOI: 10.1165/rcmb.2010-0512OC  0.56
2011 Besnard AG, Sabat R, Dumoutier L, Renauld JC, Willart M, Lambrecht B, Teixeira MM, Charron S, Fick L, Erard F, Warszawska K, Wolk K, Quesniaux V, Ryffel B, Togbe D. Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. American Journal of Respiratory and Critical Care Medicine. 183: 1153-63. PMID 21297073 DOI: 10.1164/rccm.201008-1383OC  0.56
2011 Fauconnier M, Bourigault ML, Meme S, Szeremeta F, Palomo J, Danneels A, Charron S, Fick L, Jacobs M, Beloeil JC, Ryffel B, Quesniaux VF. Protein kinase C-theta is required for development of experimental cerebral malaria. The American Journal of Pathology. 178: 212-21. PMID 21224058 DOI: 10.1016/j.ajpath.2010.11.008  0.56
2011 Doisne JM, Soulard V, Bécourt C, Amniai L, Henrot P, Havenar-Daughton C, Blanchet C, Zitvogel L, Ryffel B, Cavaillon JM, Marie JC, Couillin I, Benlagha K. Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. Journal of Immunology (Baltimore, Md. : 1950). 186: 662-6. PMID 21169541 DOI: 10.4049/jimmunol.1002725  0.44
2011 Garcia I, Olleros ML, Quesniaux VF, Jacobs M, Allie N, Nedospasov SA, Szymkowski DE, Ryffel B. Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection. Advances in Experimental Medicine and Biology. 691: 187-201. PMID 21153323 DOI: 10.1007/978-1-4419-6612-4_20  0.56
2010 Guabiraba R, Marques RE, Besnard AG, Fagundes CT, Souza DG, Ryffel B, Teixeira MM. Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice. Plos One. 5: e15680. PMID 21206747 DOI: 10.1371/journal.pone.0015680  0.44
2010 Allie N, Keeton R, Court N, Abel B, Fick L, Vasseur V, Vacher R, Olleros ML, Drutskaya MS, Guler R, Nedospasov SA, Garcia I, Ryffel B, Quesniaux VF, Jacobs M. Limited role for lymphotoxin α in the host immune response to Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 185: 4292-301. PMID 20817877 DOI: 10.4049/jimmunol.1000650  0.56
2010 Guiton R, Vasseur V, Charron S, Arias MT, Van Langendonck N, Buzoni-Gatel D, Ryffel B, Dimier-Poisson I. Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice. The Journal of Infectious Diseases. 202: 427-35. PMID 20575661 DOI: 10.1086/653738  0.36
2010 Van Maele L, Carnoy C, Cayet D, Songhet P, Dumoutier L, Ferrero I, Janot L, Erard F, Bertout J, Leger H, Sebbane F, Benecke A, Renauld JC, Hardt WD, Ryffel B, et al. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. Journal of Immunology (Baltimore, Md. : 1950). 185: 1177-85. PMID 20566828 DOI: 10.4049/jimmunol.1000115  0.52
2010 Riteau N, Gasse P, Fauconnier L, Gombault A, Couegnat M, Fick L, Kanellopoulos J, Quesniaux VF, Marchand-Adam S, Crestani B, Ryffel B, Couillin I. Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. American Journal of Respiratory and Critical Care Medicine. 182: 774-83. PMID 20522787 DOI: 10.1164/rccm.201003-0359OC  0.56
2010 Giordano G, van den Brûle S, Lo Re S, Triqueneaux P, Uwambayinema F, Yakoub Y, Couillin I, Ryffel B, Michiels T, Renauld JC, Lison D, Huaux F. Type I interferon signaling contributes to chronic inflammation in a murine model of silicosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 682-92. PMID 20513754 DOI: 10.1093/toxsci/kfq158  0.56
2010 Torres D, Dieudonné A, Ryffel B, Vilain E, Si-Tahar M, Pichavant M, Lassalle P, Trottein F, Gosset P. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 451-9. PMID 20505141 DOI: 10.4049/jimmunol.0902833  0.44
2010 Court N, Vasseur V, Vacher R, Frémond C, Shebzukhov Y, Yeremeev VV, Maillet I, Nedospasov SA, Gordon S, Fallon PG, Suzuki H, Ryffel B, Quesniaux VF. Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 7057-70. PMID 20488784 DOI: 10.4049/jimmunol.1000164  0.44
2010 Quesniaux VF, Jacobs M, Allie N, Grivennikov S, Nedospasov SA, Garcia I, Olleros ML, Shebzukhov Y, Kuprash D, Vasseur V, Rose S, Court N, Vacher R, Ryffel B. TNF in host resistance to tuberculosis infection. Current Directions in Autoimmunity. 11: 157-79. PMID 20173394 DOI: 10.1159/000289204  0.56
2010 Soares AL, Coelho FR, Guabiraba R, Kamal M, Vargaftig BB, Li L, Li J, Tavares-de-Lima W, Ryffel B. Tumor necrosis factor is not associated with intestinal ischemia/reperfusion-induced lung inflammation. Shock (Augusta, Ga.). 34: 306-13. PMID 20160673 DOI: 10.1097/SHK.0b013e3181cdc585  0.32
2010 Couper KN, Barnes T, Hafalla JC, Combes V, Ryffel B, Secher T, Grau GE, Riley EM, de Souza JB. Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. Plos Pathogens. 6: e1000744. PMID 20126448 DOI: 10.1371/journal.ppat.1000744  0.44
2010 Quesniaux V, Erard F, Ryffel B. Adjuvant activity on murine and human macrophages. Methods in Molecular Biology (Clifton, N.J.). 626: 117-30. PMID 20099125 DOI: 10.1007/978-1-60761-585-9_9  0.56
2010 Chalmin F, Ladoire S, Mignot G, Vincent J, Bruchard M, Remy-Martin JP, Boireau W, Rouleau A, Simon B, Lanneau D, De Thonel A, Multhoff G, Hamman A, Martin F, Chauffert B, ... ... Ryffel B, et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. The Journal of Clinical Investigation. 120: 457-71. PMID 20093776 DOI: 10.1172/JCI40483  0.44
2010 Victoni T, Coelho FR, Soares AL, de Freitas A, Secher T, Guabiraba R, Erard F, de Oliveira-Filho RM, Vargaftig BB, Lauvaux G, Kamal MA, Ryffel B, Moser R, Tavares-de-Lima W. Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway. Medical Microbiology and Immunology. 199: 35-42. PMID 19941004 DOI: 10.1007/s00430-009-0134-5  0.52
2009 Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. Journal of Immunology (Baltimore, Md. : 1950). 183: 8195-202. PMID 20007584 DOI: 10.4049/jimmunol.0803154  0.56
2009 Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Génin P, ... ... Ryffel B, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1Β-dependent adaptive immunity against tumors Nature Medicine. 15: 1170-1178. PMID 19767732 DOI: 10.1038/nm.2028  0.44
2009 Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF. Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression. The Journal of Biological Chemistry. 284: 23187-96. PMID 19561082 DOI: 10.1074/jbc.M109.037846  0.44
2009 Secher T, Vasseur V, Poisson DM, Mitchell JA, Cunha FQ, Alves-Filho JC, Ryffel B. Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7855-64. PMID 19494310 DOI: 10.4049/jimmunol.0804008  0.36
2009 Carlos D, Frantz FG, Souza-Júnior DA, Jamur MC, Oliver C, Ramos SG, Quesniaux VF, Ryffel B, Silva CL, Bozza MT, Faccioli LH. TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection. Microbes and Infection / Institut Pasteur. 11: 770-8. PMID 19442756 DOI: 10.1016/j.micinf.2009.04.025  0.44
2009 Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, Erard F. Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin European Journal of Immunology. 39: 1587-1596. PMID 19424969 DOI: 10.1002/eji.200838907  0.44
2009 Kirson ED, Giladi M, Gurvich Z, Itzhaki A, Mordechovich D, Schneiderman RS, Wasserman Y, Ryffel B, Goldsher D, Palti Y. Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs. Clinical & Experimental Metastasis. 26: 633-40. PMID 19387848 DOI: 10.1007/s10585-009-9262-y  0.44
2009 Olleros ML, Vesin D, Lambou AF, Janssens JP, Ryffel B, Rose S, Frémond C, Quesniaux VF, Szymkowski DE, Garcia I. Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis. The Journal of Infectious Diseases. 199: 1053-63. PMID 19222369 DOI: 10.1086/597204  0.56
2009 Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, Couillin I. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. American Journal of Respiratory and Critical Care Medicine. 179: 903-13. PMID 19218193 DOI: 10.1164/rccm.200808-1274OC  0.56
2008 Togbe D, de Sousa PL, Fauconnier M, Boissay V, Fick L, Scheu S, Pfeffer K, Menard R, Grau GE, Doan BT, Beloeil JC, Renia L, Hansen AM, Ball HJ, Hunt NH, ... Ryffel B, et al. Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. Plos One. 3: e2608. PMID 18612394 DOI: 10.1371/journal.pone.0002608  0.56
2008 Janot L, Secher T, Torres D, Maillet I, Pfeilschifter J, Quesniaux VF, Landmann R, Ryffel B, Erard F. CD14 works with toll-like receptor 2 to contribute to recognition and control of Listeria monocytogenes infection. The Journal of Infectious Diseases. 198: 115-24. PMID 18462086 DOI: 10.1086/588815  0.56
2007 Togbe D, Schnyder-Candrian S, Schnyder B, Doz E, Noulin N, Janot L, Secher T, Gasse P, Lima C, Coelho FR, Vasseur V, Erard F, Ryffel B, Couillin I, Moser R. Toll-like receptor and tumour necrosis factor dependent endotoxin-induced acute lung injury. International Journal of Experimental Pathology. 88: 387-91. PMID 18039275 DOI: 10.1111/j.1365-2613.2007.00566.x  0.56
2007 Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1872-83. PMID 17641054  0.44
2005 Torres D, Janot L, Quesniaux VF, Grivennikov SI, Maillet I, Sedgwick JD, Ryffel B, Erard F. Membrane tumor necrosis factor confers partial protection to Listeria infection. The American Journal of Pathology. 167: 1677-87. PMID 16314479 DOI: 10.1016/S0002-9440(10)61250-3  0.44
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