Bernhard Ryffel - Publications

Affiliations: 
Univ. of New Orleans, New Orleans, LA, United States 
Area:
PbA, Type I IFN, Interleukin-22, HDM, NLRP3, Caspase-1, IL-33, PIM, Tlr2, Flagellin

364 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nascimento M, Huot-Marchand S, Fanny M, Straube M, Le Bert M, Savigny F, Apetoh L, Van Snick J, Trovero F, Chamaillard M, Quesniaux VFJ, Ryffel B, Gosset P, Gombault A, Riteau N, et al. NLRP6 controls pulmonary inflammation from cigarette smoke in a gut microbiota-dependent manner. Frontiers in Immunology. 14: 1224383. PMID 38146368 DOI: 10.3389/fimmu.2023.1224383  0.8
2023 Russo RC, Quesniaux VFJ, Ryffel B. Homeostatic chemokines as putative therapeutic targets in idiopathic pulmonary fibrosis. Trends in Immunology. 44: 1014-1030. PMID 37951789 DOI: 10.1016/j.it.2023.10.003  0.578
2023 Carignon S, De Moura Rodrigues D, Gosset D, Culerier E, Huot-Marchand S, Savigny F, Kaya E, Quesniaux V, Gombault A, Couillin I, Ryffel B, Le Bert M, Riteau N. Lung inflammation and interstitial fibrosis by targeted alveolar epithelial type I cell death. Frontiers in Immunology. 14: 1261483. PMID 37841243 DOI: 10.3389/fimmu.2023.1261483  0.778
2023 de Melo BMS, Veras FP, Zwicky P, Lima D, Ingelfinger F, Varela T, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, et al. S100A9 drives the chronification of psoriasiform inflammation by inducing IL-23/type 3 immunity. The Journal of Investigative Dermatology. PMID 36921684 DOI: 10.1016/j.jid.2023.02.026  0.364
2023 Leinardi R, Pochet A, Uwambayinema F, Yakoub Y, Quesniaux V, Ryffel B, Broz P, Pavan C, Huaux F. Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure. Archives of Toxicology. 97: 1001-1015. PMID 36840754 DOI: 10.1007/s00204-023-03463-x  0.618
2022 Corrêa RO, Castro PR, Moser R, Ferreira CM, Quesniaux VFJ, Vinolo MAR, Ryffel B. Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders. Frontiers in Nutrition. 9: 1011732. PMID 36337621 DOI: 10.3389/fnut.2022.1011732  0.54
2022 Cordier-Dirikoc S, Pedretti N, Garnier J, Clarhaut-Charreau S, Ryffel B, Morel F, Bernard FX, Hamon de Almeida V, Lecron JC, Jégou JF. Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes. Frontiers in Immunology. 13: 984045. PMID 36268013 DOI: 10.3389/fimmu.2022.984045  0.389
2022 Hrdý J, Couturier-Maillard A, Boutillier D, Lapadatescu C, Blanc P, Procházka J, Pot B, Ryffel B, Grangette C, Chamaillard M. Oral supplementation with selected Lactobacillus acidophilus triggers IL-17-dependent innate defense response, activation of innate lymphoid cells type 3 and improves colitis. Scientific Reports. 12: 17591. PMID 36266398 DOI: 10.1038/s41598-022-21643-0  0.449
2022 Huot-Marchand S, Nascimento M, Culerier E, Bourenane M, Savigny F, Panek C, Serdjebi C, Le Bert M, Quesniaux VFJ, Ryffel B, Broz P, Riteau N, Gombault A, Couillin I. Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3. Frontiers in Immunology. 13: 918507. PMID 36045672 DOI: 10.3389/fimmu.2022.918507  0.822
2022 Secher T, Couturier A, Huot L, Bouscayrol H, Grandjean T, Boulard O, Hot D, Ryffel B, Chamaillard M. A protective role of NOD2 on oxazolone-induced intestinal inflammation through IL-1-mediated signaling pathway. Journal of Crohn's & Colitis. PMID 35917251 DOI: 10.1093/ecco-jcc/jjac106  0.351
2022 Roberts LB, Berkachy R, Wane M, Patel DF, Schnoeller C, Lord GM, Gounaris K, Ryffel B, Quesniaux V, Darby M, Horsnell WGC, Selkirk ME. Differential Regulation of Allergic Airway Inflammation by Acetylcholine. Frontiers in Immunology. 13: 893844. PMID 35711456 DOI: 10.3389/fimmu.2022.893844  0.635
2022 Chenuet P, Marquant Q, Fauconnier L, Youness A, Mellier M, Marchiol T, Rouxel N, Messaoud-Nacer Y, Maillet I, Ledru A, Quesniaux VFJ, Ryffel B, Horsnell W, Végran F, Apetoh L, et al. NLRP6 negatively regulates type 2 immune responses in mice. Allergy. PMID 35615773 DOI: 10.1111/all.15388  0.689
2022 Lima C, Andrade-Barros AI, Bernardo JTG, Balogh E, Quesniaux VF, Ryffel B, Lopes-Ferreira M. Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway. International Journal of Molecular Sciences. 23. PMID 35408954 DOI: 10.3390/ijms23073600  0.622
2022 Messaoud-Nacer Y, Culerier E, Rose S, Maillet I, Rouxel N, Briault S, Ryffel B, Quesniaux VFJ, Togbe D. STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS). Cell Death & Disease. 13: 269. PMID 35338116 DOI: 10.1038/s41419-022-04664-5  0.633
2021 Sedda D, Mackowiak C, Pailloux J, Culerier E, Dudas A, Rontani P, Erard N, Lefevre A, Mavel S, Emond P, Foucher F, Le Bert M, Quesniaux VFJ, Mihatsch MJ, Ryffel B, et al. Deletion of Induces Xanthinuria with Obstructive Nephropathy and Major Metabolic Disorders in Mice. Kidney360. 2: 1793-1806. PMID 35372998 DOI: 10.34067/KID.0001732021  0.465
2021 Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, ... ... Ryffel B, et al. Sepsis expands a CD39 plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. Immunity. PMID 34473957 DOI: 10.1016/j.immuni.2021.08.005  0.582
2021 Mackowiak C, Marchiol T, Paljetak HC, Fauconnier L, Palomo J, Secher T, Panek C, Sedda D, Savigny F, Erard F, Bragonzi A, Huaux F, Stoeger T, Schiller HB, Sirard JC, ... ... Ryffel B, et al. Chronic Lung Infection Is IL-1R Independent, but Relies on MyD88 Signaling. Immunohorizons. 5: 273-283. PMID 33958388 DOI: 10.4049/immunohorizons.2000095  0.847
2021 Chetty A, Darby MG, Vornewald PM, Martín-Alonso M, Filz A, Ritter M, McSorley HJ, Masson L, Smith K, Brombacher F, O'Shea MK, Cunningham AF, Ryffel B, Oudhoff MJ, Dewals BG, et al. Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection. Cell Host & Microbe. 29: 579-593.e5. PMID 33857419 DOI: 10.1016/j.chom.2021.02.004  0.404
2021 Nehmar R, Fauconnier L, Alves-Filho J, Togbe D, DeCauwer A, Bahram S, Le Bert M, Ryffel B, Georgel P. Aryl hydrocarbon receptor (Ahr)-dependent Il-22 expression by type 3 innate lymphoid cells control of acute joint inflammation. Journal of Cellular and Molecular Medicine. PMID 33734594 DOI: 10.1111/jcmm.16433  0.435
2021 Roberts LB, Schnoeller C, Berkachy R, Darby M, Pillaye J, Oudhoff MJ, Parmar N, Mackowiak C, Sedda D, Quesniaux V, Ryffel B, Vaux R, Gounaris K, Berrard S, Withers DR, et al. Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths. Science Immunology. 6. PMID 33674321 DOI: 10.1126/sciimmunol.abd0359  0.664
2020 Savigny F, Schricke C, Lacerda-Queiroz N, Meda M, Nascimento M, Huot-Marchand S, Da Gama Monteiro F, Ryffel B, Gombault A, Le Bert M, Couillin I, Riteau N. Protective Role of the Nucleic Acid Sensor STING in Pulmonary Fibrosis. Frontiers in Immunology. 11: 588799. PMID 33488589 DOI: 10.3389/fimmu.2020.588799  0.748
2020 Darby M, Roberts LB, Mackowiak C, Chetty A, Tinelli S, Schnoeller C, Quesniaux V, Berrard S, Togbe D, Selkirk ME, Ryffel B, Horsnell WGC. ILC3-derived acetylcholine promotes protease-driven allergic lung pathology. The Journal of Allergy and Clinical Immunology. PMID 33461747 DOI: 10.1016/j.jaci.2020.10.038  0.522
2020 Lima C, Falcao MAP, Andrade-Barros AI, Seni-Silva AC, Grund LZ, Balogh E, Conceiçao K, Queniaux VF, Ryffel B, Lopes-Ferreira M. Natterin an aerolysin-like fish toxin drives IL-1β-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6. International Immunopharmacology. 91: 107287. PMID 33378723 DOI: 10.1016/j.intimp.2020.107287  0.427
2020 Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG. Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression. Frontiers in Immunology. 11: 592865. PMID 33193440 DOI: 10.3389/fimmu.2020.592865  0.55
2020 Togbe D, Benmerzoug S, Jacobs M, Ryffel B, Quesniaux VFJ. Silica-related diseases in the modern world: A role for self-DNA sensing in lung inflammatory diseases. Allergy. 75: 3009-3010. PMID 33155702 DOI: 10.1111/all.14463  0.504
2020 Wiegman CH, Li F, Ryffel B, Togbe D, Chung KF. Oxidative Stress in Ozone-Induced Chronic Lung Inflammation and Emphysema: A Facet of Chronic Obstructive Pulmonary Disease. Frontiers in Immunology. 11: 1957. PMID 32983127 DOI: 10.3389/Fimmu.2020.01957  0.355
2020 Reverchon F, de Concini V, Larrigaldie V, Benmerzoug S, Briault S, Togbé D, Ryffel B, Quesniaux VFJ, Menuet A. Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments. Journal of Neuroinflammation. 17: 268. PMID 32917228 DOI: 10.1186/S12974-020-01939-6  0.621
2020 Duez C, Gross B, Marquillies P, Ledroit V, Ryffel B, Glineur C. Regulation of IL (Interleukin)-33 Production in Endothelial Cells via Kinase Activation and Fas/CD95 Upregulation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314832. PMID 32907372 DOI: 10.1161/Atvbaha.120.314832  0.509
2020 Lopes AH, Silva RL, Fonseca MD, Gomes FI, Maganin AG, Ribeiro LS, Marques LMM, Cunha FQ, Alves-Filho JC, Zamboni DS, Lopes NP, Franklin BS, Gombault A, Ramalho FS, Quesniaux VFJ, ... ... Ryffel B, et al. Molecular basis of carrageenan-induced cytokines production in macrophages. Cell Communication and Signaling : Ccs. 18: 141. PMID 32894139 DOI: 10.1186/S12964-020-00621-X  0.589
2020 Nascimento M, Huot-Marchand S, Gombault A, Panek C, Bourinet M, Fanny M, Savigny F, Schneider P, Le Bert M, Ryffel B, Riteau N, Quesniaux VFJ, Couillin I. B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure. Frontiers in Immunology. 11: 1622. PMID 32849550 DOI: 10.3389/Fimmu.2020.01622  0.812
2020 Liu Y, Qi G, Bellanti JA, Moser R, Ryffel B, Zheng SG. Regulatory T cells: A potential weapon to combat COVID-19? Medcomm. PMID 32838397 DOI: 10.1002/Mco2.12  0.56
2020 Segueni N, Jacobs M, Ryffel B. Innate type 1 immune response, but not IL-17 cells control tuberculosis infection. Biomedical Journal. PMID 32798210 DOI: 10.1016/J.Bj.2020.06.011  0.507
2020 Luiz JPM, Toller-Kawahisa JE, Viacava PR, Nascimento DC, Pereira PT, Saraiva AL, Prado DS, LeBert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology. PMID 32745297 DOI: 10.1002/Jlb.1Ma0520-016R  0.652
2020 Di Domizio J, Belkhodja C, Chenuet P, Fries A, Murray T, Mondéjar PM, Demaria O, Conrad C, Homey B, Werner S, Speiser DE, Ryffel B, Gilliet M. The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin. Nature Immunology. PMID 32661363 DOI: 10.1038/S41590-020-0721-6  0.301
2020 Wollin L, Togbe D, Ryffel B. Effects of Nintedanib in an Animal Model of Liver Fibrosis. Biomed Research International. 2020: 3867198. PMID 32337244 DOI: 10.1155/2020/3867198  0.382
2020 Hrdý J, Alard J, Couturier-Maillard A, Boulard O, Boutillier D, Delacre M, Lapadatescu C, Cesaro A, Blanc P, Pot B, Ryffel B, Chamaillard M, Grangette C. Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses. Scientific Reports. 10: 5345. PMID 32210304 DOI: 10.1038/S41598-020-62161-1  0.411
2020 Michaudel C, Bataille F, Maillet I, Fauconnier L, Colas C, Sokol H, Straube M, Couturier-Maillard A, Dumoutier L, van Snick J, Quesniaux VF, Togbe D, Ryffel B. Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation. Frontiers in Immunology. 11: 144. PMID 32161582 DOI: 10.3389/Fimmu.2020.00144  0.707
2020 Jiang X, Chen Y, Liu D, Shi T, Cheng X, He W, Li Y, Ryffel B, Zheng SG, Zheng Y. Secoeudesma sesquiterpenes lactone A alleviates inflammation and offers adjuvant protection in severe infection of carbapenem-resistant Klebsiella pneumoniae. Journal of Ethnopharmacology. 112605. PMID 31981749 DOI: 10.1016/J.Jep.2020.112605  0.541
2019 Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert L, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. The alternative cap-binding complex is required for antiviral defense in vivo. Plos Pathogens. 15: e1008155. PMID 31856218 DOI: 10.1371/Journal.Ppat.1008155  0.332
2019 Rodriguez-Cruz A, Vesin D, Ramon-Luing L, Zuñiga J, Quesniaux VFJ, Ryffel B, Lascurain R, Garcia I, Chávez-Galán L. CD3 Macrophages Deliver Proinflammatory Cytokines by a CD3- and Transmembrane TNF-Dependent Pathway and Are Increased at the BCG-Infection Site. Frontiers in Immunology. 10: 2550. PMID 31787969 DOI: 10.3389/Fimmu.2019.02550  0.659
2019 Valque H, Gouyer V, Duez C, Leboeuf C, Marquillies P, Le Bert M, Plet S, Ryffel B, Janin A, Gottrand F, Desseyn JL. Muc5b-deficient mice develop early histological lung abnormalities. Biology Open. 8. PMID 31699684 DOI: 10.1242/Bio.046359  0.386
2019 Nascimento M, Gombault A, Lacerda-Queiroz N, Panek C, Savigny F, Sbeity M, Bourinet M, Le Bert M, Riteau N, Ryffel B, Quesniaux VFJ, Couillin I. Self-DNA release and STING-dependent sensing drives inflammation to cigarette smoke in mice. Scientific Reports. 9: 14848. PMID 31619733 DOI: 10.1038/S41598-019-51427-Y  0.782
2019 Sokolowska M, Quesniaux VFJ, Akdis CA, Chung KF, Ryffel B, Togbe D. Acute Respiratory Barrier Disruption by Ozone Exposure in Mice. Frontiers in Immunology. 10: 2169. PMID 31608051 DOI: 10.3389/Fimmu.2019.02169  0.635
2019 Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 31603987 DOI: 10.1093/Gerona/Glz239  0.315
2019 Ryffel B, Alves-Filho JC. ILC2s and Basophils Team Up to Orchestrate IL-33-Induced Atopic Dermatitis. The Journal of Investigative Dermatology. 139: 2077-2079. PMID 31543211 DOI: 10.1016/J.Jid.2019.06.118  0.45
2019 Legoux F, Bellet D, Daviaud C, El Morr Y, Darbois A, Niort K, Procopio E, Salou M, Gilet J, Ryffel B, Balvay A, Foussier A, Sarkis M, El Marjou A, Schmidt F, et al. Microbial metabolites control the thymic development of mucosal-associated invariant T cells. Science (New York, N.Y.). PMID 31467190 DOI: 10.1126/Science.Aaw2719  0.347
2019 Benmerzoug S, Ryffel B, Togbe D, Quesniaux VFJ. Self-DNA Sensing in Lung Inflammatory Diseases. Trends in Immunology. PMID 31262653 DOI: 10.1016/J.It.2019.06.001  0.578
2019 Darby MG, Chetty A, Mrjden D, Rolot M, Smith K, Mackowiak C, Sedda D, Nyangahu D, Jaspan H, Toellner KM, Waisman A, Quesniaux V, Ryffel B, Cunningham AF, Dewals BG, et al. Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring. Science Advances. 5: eaav3058. PMID 31236458 DOI: 10.1126/Sciadv.Aav3058  0.575
2019 Benmerzoug S, Bounab B, Rose S, Gosset D, Biet F, Cochard T, Xavier A, Rouxel N, Fauconnier L, Horsnell WGC, Ryffel B, Togbe D, Quesniaux VFJ. Sterile Lung Inflammation Induced by Silica Exacerbates Mycobacterium tuberculosis Infection via STING-Dependent Type 2 Immunity. Cell Reports. 27: 2649-2664.e5. PMID 31141689 DOI: 10.1016/J.Celrep.2019.04.110  0.62
2019 Ryffel B, Huang F, Robinet P, Panek C, Couillin I, Erard F, Piotet J, Le Bert M, Mackowiak C, Torres Arias M, Dimier-Poisson I, Zheng SG. Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression. Frontiers in Immunology. 10: 702. PMID 31057534 DOI: 10.3389/Fimmu.2019.00702  0.658
2019 Chavez-Galan L, Vesin D, Blaser G, Uysal H, Benmerzoug S, Rose S, Ryffel B, Quesniaux VFJ, Garcia I. Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection. Scientific Reports. 9: 5297. PMID 30923339 DOI: 10.1038/S41598-019-41629-9  0.611
2019 Palomo J, Quesniaux VFJ, Togbe D, Reverchon F, Ryffel B. Unravelling the roles of innate lymphoid cells in cerebral malaria pathogenesis. Parasite Immunology. 40. PMID 29117626 DOI: 10.1111/Pim.12502  0.808
2018 Mauras A, Chain F, Faucheux A, Ruffié P, Gontier S, Ryffel B, Butel MJ, Langella P, Bermúdez-Humarán LG, Waligora-Dupriet AJ. A New Bifidobacteria Expression SysTem (BEST) to Produce and Deliver Interleukin-10 in . Frontiers in Microbiology. 9: 3075. PMID 30622516 DOI: 10.3389/Fmicb.2018.03075  0.439
2018 Normand S, Waldschmitt N, Neerincx A, Martinez-Torres RJ, Chauvin C, Couturier-Maillard A, Boulard O, Cobret L, Awad F, Huot L, Ribeiro-Ribeiro A, Lautz K, Ruez R, Delacre M, Bondu C, ... ... Ryffel B, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nature Communications. 9: 5338. PMID 30559449 DOI: 10.1038/S41467-018-07750-5  0.375
2018 Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, ... ... Ryffel B, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nature Communications. 9: 5226. PMID 30523277 DOI: 10.1038/S41467-018-07425-1  0.614
2018 Pérez MM, Martins LMS, Dias MS, Pereira CA, Leite JA, Gonçalves ECS, de Almeida PZ, de Freitas EN, Tostes RC, Ramos SG, de Zoete MR, Ryffel B, Silva JS, Carlos D. Interleukin-17/interleukin-17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high-fat diet-induced metabolic syndrome model. Immunology. PMID 30472727 DOI: 10.1111/Imm.13028  0.513
2018 Oldenhove G, Boucquey E, Taquin A, Acolty V, Bonetti L, Ryffel B, Le Bert M, Englebert K, Boon L, Moser M. PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity. Cell Reports. 25: 2053-2060.e4. PMID 30463004 DOI: 10.1016/J.Celrep.2018.10.091  0.326
2018 Nyakundi BB, Tóth A, Balogh E, Nagy B, Erdei J, Ryffel B, Paragh G, Cordero MD, Jeney V. Oxidized hemoglobin forms contribute to NLRP3 inflammasome-driven IL-1β production upon intravascular hemolysis. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30389578 DOI: 10.1016/J.Bbadis.2018.10.030  0.507
2018 Müller MB, Hoppe JM, Bideak A, Lux M, Lindenmeyer MT, Müller S, Eltrich N, Ryffel B, Vielhauer V. Exclusive expression of transmembrane TNF aggravates acute glomerulonephritis despite reduced leukocyte infiltration and inflammation. Kidney International. PMID 30389199 DOI: 10.1016/J.Kint.2018.08.012  0.411
2018 Waldschmitt N, Kitamoto S, Secher T, Zacharioudaki V, Boulard O, Floquet E, Delacre M, Lamas B, Pham HP, Six A, Richard ML, Dagorn JC, Eberl G, Langella P, Chatel JM, ... Ryffel B, et al. The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure. Gut. PMID 30279238 DOI: 10.1136/Gutjnl-2018-316757  0.376
2018 Marques RE, Besnard AG, Maillet I, Fagundes CT, Souza DG, Ryffel B, Teixeira MM, Liew FY, Guabiraba R. IL-33 contributes to disease severity in Dengue virus infection in mice. Immunology. PMID 30098206 DOI: 10.1111/Imm.12988  0.834
2018 Araujo AM, Antunes MM, Mattos MS, Diniz AB, Alvarenga DM, Nakagaki BN, Carvalho É, Lacerda VAS, Carvalho-Gontijo R, Goulart J, Mafra K, Freitas-Lopes MA, Oliveira HMC, Dutra CM, David BA, ... ... Ryffel B, et al. Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose. Cells. 7. PMID 30060463 DOI: 10.3390/Cells7080088  0.576
2018 Secher T, Maillet I, Mackowiak C, Le Bérichel J, Philippeau A, Panek C, Boury M, Oswald E, Saoudi A, Erard F, Le Bert M, Quesniaux V, Couturier-Maillard A, Ryffel B. The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice. Scientific Reports. 8: 11245. PMID 30050168 DOI: 10.1038/S41598-018-29689-9  0.64
2018 Miani M, Le Naour J, Waeckel-Enée E, Verma SC, Straube M, Emond P, Ryffel B, van Endert P, Sokol H, Diana J. Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes. Cell Metabolism. PMID 30017352 DOI: 10.1016/J.Cmet.2018.06.012  0.423
2018 Michaudel C, Fauconnier L, Julé Y, Ryffel B. Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice. Scientific Reports. 8: 10611. PMID 30006538 DOI: 10.1038/S41598-018-28261-9  0.328
2018 Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I. The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin. Frontiers in Immunology. 9: 1476. PMID 29988569 DOI: 10.3389/Fimmu.2018.01476  0.843
2018 Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I. Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy. International Journal of Molecular Sciences. 19. PMID 29973541 DOI: 10.3390/Ijms19071959  0.66
2018 Dalloul Z, Chenuet P, Dalloul I, Boyer F, Aldigier JC, Laffleur B, El Makhour Y, Ryffel B, Quesniaux VF, Togbé D, Mergny JL, Cook-Moreau J, Cogné M. G-quadruplex DNA targeting alters class switch recombination in B cells and attenuates allergic inflammation. The Journal of Allergy and Clinical Immunology. PMID 29935221 DOI: 10.1016/J.Jaci.2018.06.011  0.518
2018 Saraiva AL, Veras FP, Peres RS, Talbot J, de Lima KA, Luiz JP, Carballido JM, Cunha TM, Cunha FQ, Ryffel B, Alves-Filho JC. Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T17 cells in the lymph nodes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800285. PMID 29894669 DOI: 10.1096/Fj.201800285  0.374
2018 Benmerzoug S, Marinho FV, Rose S, Mackowiak C, Gosset D, Sedda D, Poisson E, Uyttenhove C, Van Snick J, Jacobs M, Garcia I, Ryffel B, Quesniaux VFJ. GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection. Scientific Reports. 8: 8652. PMID 29872095 DOI: 10.1038/S41598-018-26984-3  0.61
2018 Michaudel C, Maillet I, Fauconnier L, Quesniaux V, Chung KF, Wiegman C, Peter D, Ryffel B. Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation. Frontiers in Immunology. 9: 916. PMID 29867931 DOI: 10.3389/Fimmu.2018.00916  0.699
2018 Marinho FV, Benmerzoug S, Rose S, Campos PC, Marques JT, Báfica A, Barber G, Ryffel B, Oliveira SC, Quesniaux VFJ. The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection. Journal of Innate Immunity. 1-14. PMID 29791904 DOI: 10.1159/000488952  0.679
2018 Erdei J, Tóth A, Balogh E, Nyakundi BB, Bányai E, Ryffel B, Paragh G, Cordero MD, Jeney V. Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells. Oxidative Medicine and Cellular Longevity. 2018: 4310816. PMID 29743981 DOI: 10.1016/J.Atherosclerosis.2018.06.090  0.486
2018 Couturier-Maillard A, Froux N, Piotet-Morin J, Michaudel C, Brault L, Le Bérichel J, Sénéchal A, Robinet P, Chenuet P, Jejou S, Dumoutier L, Renauld JC, Iovanna J, Huber S, Quesniaux V, ... ... Ryffel B, et al. Interleukin-22-deficiency and microbiota contribute to the exacerbation of Toxoplasma gondii-induced intestinal inflammation. Mucosal Immunology. PMID 29728643 DOI: 10.1038/s41385-018-0005-8  0.428
2018 Martins LMS, Perez MM, Pereira CA, Costa FRC, Dias MS, Tostes RC, Ramos SG, de Zoete MR, Ryffel B, Silva JS, Carlos D. IL-23 promotes intestinal Th17 immunity and ameliorates obesity associated metabolic syndrome in a murine high-fat diet model. Immunology. PMID 29722014 DOI: 10.1111/Imm.12946  0.464
2018 Di Padova F, Quesniaux VFJ, Ryffel B. MyD88 as a therapeutic target for inflammatory lung diseases. Expert Opinion On Therapeutic Targets. 1-8. PMID 29658361 DOI: 10.1080/14728222.2018.1464139  0.676
2018 Cordero MD, Alcocer-Gómez E, Ryffel B. Gain of function mutation and inflammasome driven diseases in human and mouse models. Journal of Autoimmunity. PMID 29610014 DOI: 10.1016/J.Jaut.2018.03.002  0.433
2018 Anchim A, Raddi N, Zig L, Perrieau P, Le Goffic R, Ryffel B, Benihoud K. Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway. Frontiers in Immunology. 9: 124. PMID 29459860 DOI: 10.3389/Fimmu.2018.00124  0.315
2018 Michaudel C, Mackowiak C, Maillet I, Fauconnier L, Akdis C, Sokolowska M, Dreher A, Tan HT, Quesniaux VF, Ryffel B, Togbe D. Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by Interleukin-33. The Journal of Allergy and Clinical Immunology. PMID 29331644 DOI: 10.1016/j.jaci.2017.11.044  0.609
2017 Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, et al. Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nature Immunology. PMID 29255269 DOI: 10.1038/S41590-017-0013-Y  0.374
2017 Roy C, Tabiasco J, Caillon A, Delneste Y, Merot J, Favre J, Guihot AL, Martin L, Nascimento DC, Ryffel B, Robson SC, Sévigny J, Henrion D, Kauffenstein G. Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension. Purinergic Signalling. PMID 29236227 DOI: 10.1007/S11302-017-9597-9  0.369
2017 Belmellat N, Semerano L, Segueni N, Damotte D, Decker P, Ryffel B, Quesniaux V, Boissier MC, Assier E. Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection. Frontiers in Immunology. 8: 1533. PMID 29184553 DOI: 10.3389/Fimmu.2017.01533  0.613
2017 Radulovic K, Normand S, Rehman A, Delanoye-Crespin A, Chatagnon J, Delacre M, Waldschmitt N, Poulin LF, Iovanna J, Ryffel B, Rosenstiel P, Chamaillard M. A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation. Mucosal Immunology. 11: 811-819. PMID 29139477 DOI: 10.1038/Mi.2017.87  0.371
2017 Kang H, Yang K, Xiao L, Guo L, Guo C, Yan Y, Qi J, Wang F, Ryffel B, Li C, Deng L. Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway. Frontiers in Immunology. 8: 1312. PMID 29085370 DOI: 10.3389/Fimmu.2017.01312  0.381
2017 Antunes MM, Araújo AM, Diniz AB, Pereira RVS, Alvarenga DM, David BA, Rocha RM, Lopes MAF, Marchesi SC, Nakagaki BN, Carvalho É, Marques PE, Ryffel B, Quesniaux V, Brito RG, et al. IL-33 signalling in liver immune cells enhances drug-induced liver injury and inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 29032512 DOI: 10.1007/S00011-017-1098-3  0.612
2017 Chenuet P, Fauconnier L, Madouri F, Marchiol T, Rouxel N, Ledru A, Mauny P, Lory R, Uttenhove C, van Snick J, Iwakura Y, di Padova F, Quesniaux V, Togbe D, Ryffel B. Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice. Clinical Science (London, England : 1979). 131: 2533-2548. PMID 29026003 DOI: 10.1042/Cs20171034  0.834
2017 Agoro R, Benmerzoug S, Rose S, Bouyer M, Gozzelino R, Garcia I, Ryffel B, Quesniaux VFJ, Mura C. Iron-rich diet decreases mycobacterial burden and correlates with hepcidin upregulation, lower pro-inflammatory mediators and higher T cell recruitment in a model of M. bovis BCG infection. The Journal of Infectious Diseases. PMID 28973651 DOI: 10.1093/Infdis/Jix366  0.561
2017 Chavez-Galan L, Vesin D, Uysal H, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I. Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy. Frontiers in Immunology. 8: 999. PMID 28890718 DOI: 10.3389/Fimmu.2017.00999  0.65
2017 Dos Santos JC, Grund LZ, Seibert CS, Marques EE, Soares AB, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Stingray venom activates IL-33 producing cardiomyocytes, but not mast cell, to promote acute neutrophil-mediated injury. Scientific Reports. 7: 7912. PMID 28801624 DOI: 10.1038/S41598-017-08395-Y  0.711
2017 Jiang Z, Liu Y, Li C, Chang L, Wang W, Wang Z, Gao X, Ryffel B, Wu Y, Lai Y. Interleukin-36γ induced by the TLR3-SLUG-VDR axis promotes wound healing via REG3A. The Journal of Investigative Dermatology. PMID 28774595 DOI: 10.1016/J.Jid.2017.07.820  0.466
2017 Marinho FV, Benmerzoug S, Oliveira SC, Ryffel B, Quesniaux VFJ. The Emerging Roles of STING in Bacterial Infections. Trends in Microbiology. PMID 28625530 DOI: 10.1016/J.Tim.2017.05.008  0.588
2017 Kaestle M, Bartel S, Geillinger-Kästle K, Irmler M, Beckers J, Ryffel B, Eickelberg O, Krauss-Etschmann S. microRNA cluster 106a~363 is involved in T-Helper 17 (Th17) cell differentiation. Immunology. PMID 28617945 DOI: 10.1111/Imm.12775  0.303
2017 Reverchon F, Mortaud S, Sivoyon M, Maillet I, Laugeray A, Palomo J, Montécot C, Herzine A, Meme S, Meme W, Erard F, Ryffel B, Menuet A, Quesniaux VFJ. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. Plos Pathogens. 13: e1006322. PMID 28448579 DOI: 10.1371/Journal.Ppat.1006322  0.839
2017 Li C, Maillet I, Mackowiak C, Viala C, Di Padova F, Li M, Togbe D, Quesniaux V, Lai Y, Ryffel B. Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells. Cell Death & Disease. 8: e2735. PMID 28383552 DOI: 10.1038/Cddis.2017.90  0.68
2017 Carlos D, Costa FR, Pereira CA, Rocha FA, Yaochite JN, Oliveira GG, Carneiro FS, Tostes RC, Ramos SG, Zamboni DS, Camara NO, Ryffel B, Silva JS. Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model. Frontiers in Immunology. 8: 164. PMID 28289409 DOI: 10.3389/Fimmu.2017.00164  0.475
2017 Hsu NJ, Francisco NM, Keeton R, Allie N, Quesniaux VF, Ryffel B, Jacobs M. Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis. Frontiers in Immunology. 8: 180. PMID 28280495 DOI: 10.3389/Fimmu.2017.00180  0.651
2017 Tan Z, Liu Q, Jiang R, Lv L, Shoto SS, Maillet I, Quesniaux V, Tang J, Zhang W, Sun B, Ryffel B. Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells. Cellular & Molecular Immunology. PMID 28194023 DOI: 10.1038/Cmi.2016.63  0.658
2017 Hassane M, Demon D, Soulard D, Fontaine J, Keller LE, Patin EC, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening JW, Sirard JC, Faveeuw C, Lamkanfi M, Trottein F, et al. Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections. Mucosal Immunology. PMID 28051086 DOI: 10.1038/Mi.2016.113  0.531
2017 Assier E, Belmellat N, Semerano L, Ryffel B, Decker P, Quesniaux V, Boissier M. 06.11 Anti-tnf-α vaccination protects from experimental arthritis without negatively affecting resistance to mycobacterium tuberculosis infection Annals of the Rheumatic Diseases. 76. DOI: 10.1136/Annrheumdis-2016-211053.11  0.619
2016 Grund LZ, Novaski I, Quesniaux VF, Ryffel B, Lopes-Ferreira M, Lima C. Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R. Autoimmunity. 1-16. PMID 28010135 DOI: 10.1080/08916934.2016.1261834  0.675
2016 Dambuza IM, Keeton R, Hsu NJ, Allie N, Quesniaux VF, Ryffel B, Jacobs M. Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation. Scientific Reports. 6: 39499. PMID 27995986 DOI: 10.1038/Srep39499  0.654
2016 Segueni N, Tritto E, Bourigault ML, Rose S, Erard F, Le Bert M, Jacobs M, Di Padova F, Stiehl DP, Moulin P, Brees D, Chibout SD, Ryffel B, Kammüller M, Quesniaux VF. Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization. Scientific Reports. 6: 36923. PMID 27853279 DOI: 10.1038/Srep36923  0.694
2016 Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, ... ... Ryffel B, et al. PKC theta controls ILC2 and Th2 responses to house dust mite allergen. The Journal of Allergy and Clinical Immunology. PMID 27746240 DOI: 10.1016/J.Jaci.2016.08.044  0.83
2016 Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, Bellier B, Togbe D, Ryffel B, Klatzmann D, Baron-Bodo V, Moingeon P. The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation. Mucosal Immunology. PMID 27731323 DOI: 10.1038/Mi.2016.87  0.497
2016 Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, Chenuet P, Guillou N, Le Bérichel J, Kisielow M, Flodby P, Borok Z, Crandall ED, Le Bert M, Quesniaux V, ... ... Ryffel B, et al. IL-1R1-MyD88 axis elicits papain-induced lung inflammation. European Journal of Immunology. PMID 27569535 DOI: 10.1002/Eji.201646366  0.851
2016 Maillet I, Perche O, Pâris A, Richard O, Gombault A, Herzine A, Pichon J, Huaux F, Mortaud S, Ryffel B, Quesniaux V, Montecot-Dubourg C. Glufosinate aerogenic exposure induces glutamate and IL-1 receptors dependent lung inflammation. Clinical Science (London, England : 1979). PMID 27549113 DOI: 10.1042/Cs20160530  0.676
2016 Chavez-Galan L, Vesin D, Segueni N, Prasad P, Buser-Llinares R, Blaser G, Pache JC, Ryffel B, Quesniaux VF, Garcia I. Tumor Necrosis Factor and Its Receptors Are Crucial to Control Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection in a Murine Model. The American Journal of Pathology. PMID 27456129 DOI: 10.1016/J.Ajpath.2016.05.015  0.661
2016 Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S. Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension. The European Respiratory Journal. 48: 470-83. PMID 27418552 DOI: 10.1183/13993003.01448-2015  0.498
2016 Pietrocola F, Pol J, Vacchelli E, Rao S, Enot DP, Baracco EE, Levesque S, Castoldi F, Jacquelot N, Yamazaki T, Senovilla L, Marino G, Aranda F, Durand S, Sica V, ... ... Ryffel B, et al. Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell. 30: 147-60. PMID 27411589 DOI: 10.1016/J.Ccell.2016.05.016  0.321
2016 Michaudel C, Couturier-Maillard A, Chenuet P, Maillet I, Mura C, Couillin I, Gombault A, Quesniaux VF, Huaux F, Ryffel B. Inflammasome, IL-1 and inflammation in ozone-induced lung injury. American Journal of Clinical and Experimental Immunology. 5: 33-40. PMID 27168953  0.616
2016 Lamas B, Richard ML, Leducq V, Pham HP, Michel ML, Da Costa G, Bridonneau C, Jegou S, Hoffmann TW, Natividad JM, Brot L, Taleb S, Couturier-Maillard A, Nion-Larmurier I, Merabtene F, ... ... Ryffel B, et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nature Medicine. PMID 27158904 DOI: 10.1038/Nm.4102  0.383
2016 Savers A, Rasid O, Parlato M, Brock M, Jouvion G, Ryffel B, Cavaillon JM, Eberl G, Ibrahim-Granet O. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge. Plos One. 11: e0153829. PMID 27078879 DOI: 10.1371/Journal.Pone.0153829  0.449
2016 Hanot Mambres D, Machelart A, Potemberg G, De Trez C, Ryffel B, Letesson JJ, Muraille E. Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice. Journal of Immunology (Baltimore, Md. : 1950). 196: 3780-93. PMID 27036913 DOI: 10.4049/Jimmunol.1502265  0.541
2016 Cochez PM, Michiels C, Hendrickx E, Van Belle AB, Lemaire MM, Dauguet N, Warnier G, de Heusch M, Togbe D, Ryffel B, Coulie PG, Renauld JC, Dumoutier L. AhR modulates the IL-22-producing cell proliferation/recruitment in imiquimod-induced psoriasis mouse model. European Journal of Immunology. 46: 1449-59. PMID 27000947 DOI: 10.1002/Eji.201546070  0.48
2016 Segueni N, Benmerzoug S, Rose S, Gauthier A, Bourigault ML, Reverchon F, Philippeau A, Erard F, Le Bert M, Bouscayrol H, Wachter T, Garcia I, Kollias G, Jacobs M, Ryffel B, et al. Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection. Scientific Reports. 6: 22454. PMID 26931771 DOI: 10.1038/Srep22454  0.65
2016 Assier E, Belmellat N, Semerano L, Ryffel B, Decker P, Quesniaux V, Boissier M. La vaccination anti-TNF-alpha protège les souris des arthrites mais ne favorise pas les infections dans les modèles à Mycobacterium tuberculosis et Listeria monocytogenes Revue Du Rhumatisme. 83: A300-A301. DOI: 10.1016/S1169-8330(16)30695-0  0.53
2016 Kammueller M, DiPadova F, Chibout S, Wright T, Bourigault M, Segueni N, Rose S, Ryffel B, Quesniaux V. Comparison of anti-IL-17A, IL-17F and TNF-α antibodies on host resistance to acute Mycobacterium tuberculosis infection in mice Journal of Dermatological Science. 84: e64. DOI: 10.1016/J.Jdermsci.2016.08.198  0.664
2015 Amaral FA, Bastos LF, Oliveira TH, Dias AC, Oliveira VL, Tavares LD, Costa VV, Galvão I, Soriani FM, Szymkowski DE, Ryffel B, Souza DG, Teixeira MM. Transmembrane TNF-α is sufficient for articular inflammation and hypernociception in a mouse model of gout. European Journal of Immunology. PMID 26449770 DOI: 10.1002/Eji.201545798  0.462
2015 Hanot Mambres D, Machelart A, Vanderwinden JM, De Trez C, Ryffel B, Letesson JJ, Muraille E. In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice. Plos One. 10: e0137835. PMID 26376185 DOI: 10.1371/Journal.Pone.0137835  0.51
2015 Pinto LG, Talbot J, Peres RS, Franca RF, Ferreira SH, Ryffel B, Aves-Filho JC, Figueiredo F, Cunha TM, Cunha FQ. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy. 17: 235. PMID 26330334 DOI: 10.1186/S13075-015-0759-2  0.448
2015 Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26310268 DOI: 10.1096/Fj.14-267146  0.675
2015 Rabeony H, Pohin M, Vasseur P, Petit-Paris I, Jégou JF, Favot L, Frouin E, Boutet MA, Blanchard F, Togbe D, Ryffel B, Bernard FX, Lecron JC, Morel F. IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome. European Journal of Immunology. 45: 2847-57. PMID 26147228 DOI: 10.1002/Eji.201445215  0.505
2015 Olleros ML, Chavez-Galan L, Segueni N, Bourigault ML, Vesin D, Kruglov AA, Drutskaya MS, Bisig R, Ehlers S, Aly S, Walter K, Kuprash DV, Chouchkova M, Kozlov SV, Erard F, ... Ryffel B, et al. Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF. Infection and Immunity. 83: 3612-23. PMID 26123801 DOI: 10.1128/IAI.00743-15  0.561
2015 Francisco NM, Hsu NJ, Keeton R, Randall P, Sebesho B, Allie N, Govender D, Quesniaux V, Ryffel B, Kellaway L, Jacobs M. TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis. Journal of Neuroinflammation. 12: 125. PMID 26112704 DOI: 10.1186/S12974-015-0345-1  0.603
2015 Bruchard M, Rebé C, Derangère V, Togbé D, Ryffel B, Boidot R, Humblin E, Hamman A, Chalmin F, Berger H, Chevriaux A, Limagne E, Apetoh L, Végran F, Ghiringhelli F. The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. Nature Immunology. 16: 859-70. PMID 26098997 DOI: 10.1038/Ni.3202  0.456
2015 Hernández PP, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, Gronke K, Ryffel B, Hölscher C, Dumoutier L, Renauld JC, Suerbaum S, Staeheli P, Diefenbach A. Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nature Immunology. 16: 698-707. PMID 26006013 DOI: 10.1038/Ni.3180  0.458
2015 Segueni N, Vigne S, Palmer G, Bourigault ML, Olleros ML, Vesin D, Garcia I, Ryffel B, Quesniaux VF, Gabay C. Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection. Plos One. 10: e0126058. PMID 25950182 DOI: 10.1371/Journal.Pone.0126058  0.711
2015 Randall PJ, Hsu NJ, Quesniaux V, Ryffel B, Jacobs M. Mycobacterium tuberculosis infection of the 'non-classical immune cell'. Immunology and Cell Biology. PMID 25801479 DOI: 10.1038/Icb.2015.43  0.594
2015 Madouri F, Guillou N, Fauconnier L, Marchiol T, Rouxel N, Chenuet P, Ledru A, Apetoh L, Ghiringhelli F, Chamaillard M, Zheng SG, Trovero F, Quesniaux VF, Ryffel B, Togbe D. Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation. Journal of Molecular Cell Biology. 7: 351-65. PMID 25714839 DOI: 10.1093/Jmcb/Mjv012  0.848
2015 Lopes AH, Talbot J, Silva RL, Lima JB, França RO, Verri WA, Mascarenhas DP, Ryffel B, Cunha FQ, Zamboni DS, Cunha TM. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain. 156: 451-9. PMID 25687541 DOI: 10.1097/01.J.Pain.0000460322.72396.53  0.456
2015 Palomo J, Reverchon F, Piotet J, Besnard AG, Couturier-Maillard A, Maillet I, Tefit M, Erard F, Mazier D, Ryffel B, Quesniaux VF. Critical role of IL-33 receptor ST2 in experimental cerebral malaria development. European Journal of Immunology. 45: 1354-65. PMID 25682948 DOI: 10.1002/Eji.201445206  0.839
2015 Besnard AG, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw TN, Couper KN, Ryffel B, Liew FY. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. Plos Pathogens. 11: e1004607. PMID 25659095 DOI: 10.1371/Journal.Ppat.1004607  0.853
2015 Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE. In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria. Plos Pathogens. 11: e1004598. PMID 25658925 DOI: 10.1371/Journal.Ppat.1004598  0.359
2015 François A, Gombault A, Villeret B, Alsaleh G, Fanny M, Gasse P, Adam SM, Crestani B, Sibilia J, Schneider P, Bahram S, Quesniaux V, Ryffel B, Wachsmann D, Gottenberg JE, et al. B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis. Journal of Autoimmunity. 56: 1-11. PMID 25441030 DOI: 10.1016/J.Jaut.2014.08.003  0.684
2015 Huaux F, Lo Re S, Giordano G, Uwambayinema F, Devosse R, Yakoub Y, Panin N, Palmai-Pallag M, Rabolli V, Delos M, Marbaix E, Dauguet N, Couillin I, Ryffel B, Renauld JC, et al. IL-1α induces CD11b(low) alveolar macrophage proliferation and maturation during granuloma formation. The Journal of Pathology. 235: 698-709. PMID 25421226 DOI: 10.1002/Path.4487  0.537
2015 Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS. Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection. The Journal of Infectious Diseases. 211: 1015-26. PMID 25274569 DOI: 10.1093/Infdis/Jiu531  0.535
2015 Segueni N, Vigne S, Palmer G, Bourigault ML, Olleros ML, Vesin D, Garcia I, Ryffel B, Quesniaux VFJ, Gabay C. Limited contribution of IL-36 versus IL-1 and TNF pathways in host response to mycobacterial infection Plos One. 10. DOI: 10.1371/journal.pone.0126058  0.637
2015 Belmellat N, Faunonnier L, Ryffel B, Boissier M, Assier E. A5.11 Vaccination against TNF and side effects inlisteriainfection model Annals of the Rheumatic Diseases. 74: A51.2-A51. DOI: 10.1136/Annrheumdis-2015-207259.117  0.372
2015 Parpaleix A, Houssaini A, Latiri M, Abid S, Wan F, Amsellem V, Ryffel B, Marcos E, Couillin I, Adnot S. Involvement of interleukin-1 receptor (IL1R1) and myeloid differentiation primary response gene 88 (MyD88) signaling in pulmonary hypertension (PH) Revue Des Maladies Respiratoires. 32: 326-327. DOI: 10.1016/J.Rmr.2015.02.056  0.513
2015 Fanny M, Gombault A, Francois F, Villeret B, Ryffel B, Wachhsmann D, Gottenberg J-, Couillin I. B-cell activating factor regulates IL-1β- and IL-17A-mediated pulmonary fibrosis in mice Revue Des Maladies Respiratoires. 32: 311. DOI: 10.1016/J.Rmr.2015.02.021  0.514
2015 François A, Gombault A, Villeret B, Alsaleh G, Fanny M, Gasse P, Adam SM, Crestani B, Sibilia J, Schneider P, Bahram S, Quesniaux V, Ryffel B, Wachsmann D, Gottenberg JE, et al. B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis Journal of Autoimmunity. 56: 1-11. DOI: 10.1016/j.jaut.2014.08.003  0.612
2014 Palomo J, Marchiol T, Piotet J, Fauconnier L, Robinet M, Reverchon F, Le Bert M, Togbe D, Buijs-Offerman R, Stolarczyk M, Quesniaux VF, Scholte BJ, Ryffel B. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection. Plos One. 9: e114884. PMID 25500839 DOI: 10.1371/Journal.Pone.0114884  0.827
2014 Niedbala W, Besnard AG, Nascimento DC, Donate PB, Sonego F, Yip E, Guabiraba R, Chang HD, Fukada SY, Salmond RJ, Schmitt E, Bopp T, Ryffel B, Liew FY. Nitric oxide enhances Th9 cell differentiation and airway inflammation. Nature Communications. 5: 4575. PMID 25099390 DOI: 10.1038/Ncomms5575  0.825
2014 Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, et al. Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proceedings of the National Academy of Sciences of the United States of America. 111: E3432-40. PMID 25099355 DOI: 10.1073/Pnas.1408780111  0.653
2014 Végran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, Chalmin F, Rébé C, Dérangère V, Ryffel B, Kato M, Prévost-Blondel A, Ghiringhelli F, Apetoh L. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nature Immunology. 15: 758-66. PMID 24973819 DOI: 10.1038/Ni.2925  0.479
2014 Arifa RD, Madeira MF, de Paula TP, Lima RL, Tavares LD, Menezes-Garcia Z, Fagundes CT, Rachid MA, Ryffel B, Zamboni DS, Teixeira MM, Souza DG. Inflammasome activation is reactive oxygen species dependent and mediates irinotecan-induced mucositis through IL-1β and IL-18 in mice. The American Journal of Pathology. 184: 2023-34. PMID 24952429 DOI: 10.1016/J.Ajpath.2014.03.012  0.502
2014 Vitry MA, Hanot Mambres D, De Trez C, Akira S, Ryffel B, Letesson JJ, Muraille E. Humoral immunity and CD4+ Th1 cells are both necessary for a fully protective immune response upon secondary infection with Brucella melitensis. Journal of Immunology (Baltimore, Md. : 1950). 192: 3740-52. PMID 24646742 DOI: 10.4049/Jimmunol.1302561  0.426
2014 Geisler K, Reischer A, Kroeger I, Jacobs B, Meinhardt K, Bauer R, Ryffel B, Mackensen A, Ullrich E. Nilotinib combined with interleukin-2 mediates antitumor and immunological effects in a B16 melanoma model. Oncology Reports. 31: 2015-20. PMID 24626639 DOI: 10.3892/Or.2014.3070  0.5
2014 Olekhnovitch R, Ryffel B, Müller AJ, Bousso P. Collective nitric oxide production provides tissue-wide immunity during Leishmania infection. The Journal of Clinical Investigation. 124: 1711-22. PMID 24614106 DOI: 10.1172/Jci72058  0.354
2014 Li C, Li H, Jiang Z, Zhang T, Wang Y, Li Z, Wu Y, Ji S, Xiao S, Ryffel B, Radek KA, Xia Z, Lai Y. Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin. Plos Pathogens. 10: e1003918. PMID 24586149 DOI: 10.1371/Journal.Ppat.1003918  0.504
2014 Keeton R, Allie N, Dambuza I, Abel B, Hsu NJ, Sebesho B, Randall P, Burger P, Fick E, Quesniaux VF, Ryffel B, Jacobs M. Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis. The Journal of Clinical Investigation. 124: 1537-51. PMID 24569452 DOI: 10.1172/Jci45005  0.699
2014 Randall PJ, Hsu NJ, Lang D, Cooper S, Sebesho B, Allie N, Keeton R, Francisco NM, Salie S, Labuschagné A, Quesniaux V, Ryffel B, Kellaway L, Jacobs M. Neurons are host cells for Mycobacterium tuberculosis. Infection and Immunity. 82: 1880-90. PMID 24566619 DOI: 10.1128/Iai.00474-13  0.55
2014 Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. The Journal of Pharmacology and Experimental Therapeutics. 349: 209-20. PMID 24556663 DOI: 10.1124/Jpet.113.208223  0.618
2014 Faure E, Mear JB, Faure K, Normand S, Couturier-Maillard A, Grandjean T, Balloy V, Ryffel B, Dessein R, Chignard M, Uyttenhove C, Guery B, Gosset P, Chamaillard M, Kipnis E. Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome. American Journal of Respiratory and Critical Care Medicine. 189: 799-811. PMID 24555512 DOI: 10.1164/Rccm.201307-1358Oc  0.343
2014 Chen M, Lin X, Liu Y, Li Q, Deng Y, Liu Z, Brand D, Guo Z, He X, Ryffel B, Zheng SG. The function of BAFF on T helper cells in autoimmunity. Cytokine & Growth Factor Reviews. 25: 301-5. PMID 24411564 DOI: 10.1016/J.Cytogfr.2013.12.011  0.523
2014 Guabiraba R, Ryffel B. Dengue virus infection: current concepts in immune mechanisms and lessons from murine models. Immunology. 141: 143-56. PMID 24182427 DOI: 10.1111/Imm.12188  0.45
2014 Almeida PE, Roque NR, Magalhães KG, Mattos KA, Teixeira L, Maya-Monteiro C, Almeida CJ, Castro-Faria-Neto HC, Ryffel B, Quesniaux VF, Bozza PT. Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection. Biochimica Et Biophysica Acta. 1841: 97-107. PMID 24120921 DOI: 10.1016/J.Bbalip.2013.10.008  0.612
2014 Ma J, Liu Y, Li Y, Gu J, Liu J, Tang J, Wang J, Ryffel B, Shen Y, Brand D, Liu Z, Zheng SG. Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells. Journal of Leukocyte Biology. 95: 275-83. PMID 24082012 DOI: 10.1189/Jlb.0513297  0.511
2014 Van Maele L, Fougeron D, Janot L, Didierlaurent A, Cayet D, Tabareau J, Rumbo M, Corvo-Chamaillard S, Boulenouar S, Jeffs S, Vande Walle L, Lamkanfi M, Lemoine Y, Erard F, Hot D, ... ... Ryffel B, et al. Airway structural cells regulate TLR5-mediated mucosal adjuvant activity. Mucosal Immunology. 7: 489-500. PMID 24064672 DOI: 10.1038/Mi.2013.66  0.806
2014 Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, Wang J, Fan H, Shen Y, Ryffel B, Brand D, Quismorio F, Liu Z, Horwitz DA, Xu A, et al. Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. Journal of Molecular Cell Biology. 6: 81-92. PMID 23861553 DOI: 10.1093/Jmcb/Mjt026  0.537
2014 Togbe D, Besnard A, Madouri F, Couillin I, Gombault A, Baron L, Froux N, Maillard A, Erard F, Snick J, Uyttenhove C, Quesniaux V, Ryffel B. NLRP3 Inflammasome Activation Leading to IL-1 – IL-17 Dependent Lung Inflammation and Fibrosis Current Respiratory Medicine Reviews. 10: 64-70. DOI: 10.2174/1573398X10666140617001526  0.83
2013 Bourigault ML, Segueni N, Rose S, Court N, Vacher R, Vasseur V, Erard F, Le Bert M, Garcia I, Iwakura Y, Jacobs M, Ryffel B, Quesniaux VF. Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG. Immunity, Inflammation and Disease. 1: 47-62. PMID 25400917 DOI: 10.1002/Iid3.9  0.695
2013 Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, ... ... Ryffel B, et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science (New York, N.Y.). 342: 971-6. PMID 24264990 DOI: 10.1126/Science.1240537  0.324
2013 Secher T, Fas S, Fauconnier L, Mathieu M, Rutschi O, Ryffel B, Rudolf M. The anti-Pseudomonas aeruginosa antibody Panobacumab is efficacious on acute pneumonia in neutropenic mice and has additive effects with meropenem. Plos One. 8: e73396. PMID 24023870 DOI: 10.1371/Journal.Pone.0073396  0.351
2013 Besnard AG, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B. CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model. Journal of Leukocyte Biology. 94: 1317-23. PMID 23975892 DOI: 10.1189/Jlb.0313140  0.8
2013 Madeira MF, Queiroz-Junior CM, Cisalpino D, Werneck SM, Kikuchi H, Fujise O, Ryffel B, Silva TA, Teixeira MM, Souza DG. MyD88 is essential for alveolar bone loss induced by Aggregatibacter actinomycetemcomitans lipopolysaccharide in mice. Molecular Oral Microbiology. 28: 415-24. PMID 23906379 DOI: 10.1111/Omi.12034  0.385
2013 Villeret B, Brault L, Couturier-Maillard A, Robinet P, Vasseur V, Secher T, Dimier-Poisson I, Jacobs M, Zheng SG, Quesniaux VF, Ryffel B. Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice. American Journal of Clinical and Experimental Immunology. 2: 107-16. PMID 23885328  0.688
2013 Tan Z, Qian X, Jiang R, Liu Q, Wang Y, Chen C, Wang X, Ryffel B, Sun B. IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. Journal of Immunology (Baltimore, Md. : 1950). 191: 1835-44. PMID 23842754 DOI: 10.4049/Jimmunol.1203013  0.445
2013 Carlos D, Spiller F, Souto FO, Trevelin SC, Borges VF, de Freitas A, Alves-Filho JC, Silva JS, Ryffel B, Cunha FQ. Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model. Journal of Immunology (Baltimore, Md. : 1950). 191: 1373-82. PMID 23817413 DOI: 10.4049/Jimmunol.1202907  0.345
2013 Palomo J, Fauconnier M, Coquard L, Gilles M, Meme S, Szeremeta F, Fick L, Franetich JF, Jacobs M, Togbe D, Beloeil JC, Mazier D, Ryffel B, Quesniaux VF. Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA. European Journal of Immunology. 43: 2683-95. PMID 23780878 DOI: 10.1002/Eji.201343327  0.819
2013 Togbe D, Fauconnier L, Madouri F, Marchiol T, Chenuet P, Rouxel N, Ledru A, Erard F, Quesniaux V, Ryffel B. Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation. Isrn Allergy. 2013: 971036. PMID 23738146 DOI: 10.1155/2013/971036  0.851
2013 Garcia CC, Weston-Davies W, Russo RC, Tavares LP, Rachid MA, Alves-Filho JC, Machado AV, Ryffel B, Nunn MA, Teixeira MM. Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury. Plos One. 8: e64443. PMID 23696894 DOI: 10.1371/Journal.Pone.0064443  0.376
2013 Allie N, Grivennikov SI, Keeton R, Hsu NJ, Bourigault ML, Court N, Fremond C, Yeremeev V, Shebzukhov Y, Ryffel B, Nedospasov SA, Quesniaux VF, Jacobs M. Prominent role for T cell-derived tumour necrosis factor for sustained control of Mycobacterium tuberculosis infection. Scientific Reports. 3: 1809. PMID 23657146 DOI: 10.1038/Srep01809  0.654
2013 Berger H, Végran F, Chikh M, Gilardi F, Ladoire S, Bugaut H, Mignot G, Chalmin F, Bruchard M, Derangère V, Chevriaux A, Rébé C, Ryffel B, Pot C, Hichami A, et al. SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth. Cancer Research. 73: 3578-90. PMID 23619236 DOI: 10.1158/0008-5472.Can-12-4018  0.476
2013 Guabiraba R, Besnard AG, Marques RE, Maillet I, Fagundes CT, Conceição TM, Rust NM, Charreau S, Paris I, Lecron JC, Renauld JC, Quesniaux V, Da Poian AT, Arruda LB, Souza DG, ... Ryffel B, et al. IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection. European Journal of Immunology. 43: 1529-44. PMID 23505056 DOI: 10.1002/Eji.201243229  0.841
2013 Deroide N, Li X, Lerouet D, Van Vré E, Baker L, Harrison J, Poittevin M, Masters L, Nih L, Margaill I, Iwakura Y, Ryffel B, Pocard M, Tedgui A, Kubis N, et al. MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury. The Journal of Clinical Investigation. 123: 1176-81. PMID 23454767 DOI: 10.1172/Jci65167  0.494
2013 Chen M, Su W, Lin X, Guo Z, Wang J, Zhang Q, Brand D, Ryffel B, Huang J, Liu Z, He X, Le AD, Zheng SG. Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation. Arthritis and Rheumatism. 65: 1181-93. PMID 23400582 DOI: 10.1002/Art.37894  0.508
2013 Torres M, Guiton R, Lacroix-Lamandé S, Ryffel B, Leman S, Dimier-Poisson I. MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection. Journal of Neuroinflammation. 10: 19. PMID 23374751 DOI: 10.1186/1742-2094-10-19  0.446
2013 Tan Z, Jiang R, Wang X, Wang Y, Lu L, Liu Q, Zheng SG, Sun B, Ryffel B. RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia-reperfusion injury. Journal of Molecular Cell Biology. 5: 143-6. PMID 23362310 DOI: 10.1093/Jmcb/Mjs065  0.572
2013 Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, et al. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. The Journal of Clinical Investigation. 123: 700-11. PMID 23281400 DOI: 10.1172/Jci62236  0.327
2013 Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nature Medicine. 19: 57-64. PMID 23202296 DOI: 10.1038/Nm.2999  0.473
2013 Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, ... ... Ryffel B, et al. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 62: 1714-23. PMID 23172891 DOI: 10.1136/Gutjnl-2011-301785  0.663
2013 Madeira MFM, Queiroz-Junior CM, Cisalpino D, Werneck SMC, Kikuchi H, Fujise O, Ryffel B, Silva TA, Teixeira MM, Souza DG. MyD88 is essential for alveolar bone loss induced byAggregatibacter actinomycetemcomitansLPS in mice Molecular Oral Microbiology. DOI: 10.1111/J.2041-1014.2013.12034.X  0.303
2012 Schnyder-Candrian S, Maillet I, Le Bert M, Brault L, Jacobs M, Ryffel B, Schnyder B, Moser R. Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation. Journal of Allergy. 2012: 245909. PMID 23304174 DOI: 10.1155/2012/245909  0.45
2012 Riteau N, Baron L, Villeret B, Guillou N, Savigny F, Ryffel B, Rassendren F, Le Bert M, Gombault A, Couillin I. ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation. Cell Death & Disease. 3: e403. PMID 23059822 DOI: 10.1038/Cddis.2012.144  0.757
2012 Vitry MA, De Trez C, Goriely S, Dumoutier L, Akira S, Ryffel B, Carlier Y, Letesson JJ, Muraille E. Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice. Infection and Immunity. 80: 4271-80. PMID 23006848 DOI: 10.1128/Iai.00761-12  0.421
2012 Su D, Musaji A, Legrain S, Detalle L, van der Kaa J, Verbeek JS, Ryffel B, Coutelier JP. Antibody-independent thrombocytopenia in lactate dehydrogenase-elevating virus-infected mice. Journal of Virology. 86: 12414-6. PMID 22933286 DOI: 10.1128/Jvi.00745-12  0.347
2012 Sorgi CA, Rose S, Court N, Carlos D, Paula-Silva FW, Assis PA, Frantz FG, Ryffel B, Quesniaux V, Faccioli LH. GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands. Plos One. 7: e40523. PMID 22808181 DOI: 10.1371/Journal.Pone.0040523  0.623
2012 Xu W, Lan Q, Chen M, Chen H, Zhu N, Zhou X, Wang J, Fan H, Yan CS, Kuang JL, Warburton D, Togbe D, Ryffel B, Zheng SG, Shi W. Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. Plos One. 7: e40314. PMID 22792275 DOI: 10.1371/Journal.Pone.0040314  0.58
2012 Lan Q, Zhou X, Fan H, Chen M, Wang J, Ryffel B, Brand D, Ramalingam R, Kiela PR, Horwitz DA, Liu Z, Zheng SG. Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome. Journal of Molecular Cell Biology. 4: 409-19. PMID 22773728 DOI: 10.1093/Jmcb/Mjs040  0.557
2012 Su W, Fan H, Chen M, Wang J, Brand D, He X, Quesniaux V, Ryffel B, Zhu L, Liang D, Zheng SG. Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1. The Journal of Allergy and Clinical Immunology. 130: 444-52.e7. PMID 22738679 DOI: 10.1016/J.Jaci.2012.05.011  0.669
2012 Ivanov S, Fontaine J, Paget C, Macho Fernandez E, Van Maele L, Renneson J, Maillet I, Wolf NM, Rial A, Léger H, Ryffel B, Frisch B, Chabalgoity JA, Sirard JC, Benecke A, et al. Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide. The Journal of Infectious Diseases. 206: 723-34. PMID 22723642 DOI: 10.1093/infdis/jis413  0.311
2012 Chen M, Guo Z, Ju W, Ryffel B, He X, Zheng SG. The development and function of follicular helper T cells in immune responses. Cellular & Molecular Immunology. 9: 375-9. PMID 22659733 DOI: 10.1038/Cmi.2012.18  0.559
2012 Kong N, Lan Q, Chen M, Wang J, Shi W, Horwitz DA, Quesniaux V, Ryffel B, Liu Z, Brand D, Zou H, Zheng SG. Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance. Arthritis and Rheumatism. 64: 2548-58. PMID 22605463 DOI: 10.1002/Art.34513  0.704
2012 Secher T, Rodrigues Coelho F, Noulin N, Lino Dos Santos Franco A, Quesniaux V, Lignon J, Mitchell J, Moser R, Gomes E, Mirotti L, Tavares-de-Lima W, Ryffel B, Vargaftig BB, Russo M. Enhancement of methacholine-evoked tracheal contraction induced by bacterial lipopolysaccharides depends on epithelium and tumor necrosis factor. Journal of Allergy. 2012: 494085. PMID 22481960 DOI: 10.1155/2012/494085  0.625
2012 Chapman R, Shephard E, Stutz H, Douglass N, Sambandamurthy V, Garcia I, Ryffel B, Jacobs W, Williamson AL. Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells. Plos One. 7: e32769. PMID 22479338 DOI: 10.1371/Journal.Pone.0032769  0.3
2012 Copin R, Vitry MA, Hanot Mambres D, Machelart A, De Trez C, Vanderwinden JM, Magez S, Akira S, Ryffel B, Carlier Y, Letesson JJ, Muraille E. In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice. Plos Pathogens. 8: e1002575. PMID 22479178 DOI: 10.1371/Journal.Ppat.1002575  0.457
2012 Chalmin F, Mignot G, Bruchard M, Chevriaux A, Végran F, Hichami A, Ladoire S, Derangère V, Vincent J, Masson D, Robson SC, Eberl G, Pallandre JR, Borg C, Ryffel B, et al. Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity. 36: 362-73. PMID 22406269 DOI: 10.1016/J.Immuni.2011.12.019  0.438
2012 Paget C, Ivanov S, Fontaine J, Renneson J, Blanc F, Pichavant M, Dumoutier L, Ryffel B, Renauld JC, Gosset P, Gosset P, Si-Tahar M, Faveeuw C, Trottein F. Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages. The Journal of Biological Chemistry. 287: 8816-29. PMID 22294696 DOI: 10.1074/Jbc.M111.304758  0.529
2012 Fauconnier M, Palomo J, Bourigault ML, Meme S, Szeremeta F, Beloeil JC, Danneels A, Charron S, Rihet P, Ryffel B, Quesniaux VF. IL-12Rβ2 is essential for the development of experimental cerebral malaria. Journal of Immunology (Baltimore, Md. : 1950). 188: 1905-14. PMID 22238458 DOI: 10.4049/Jimmunol.1101978  0.841
2012 Besnard AG, Togbe D, Couillin I, Tan Z, Zheng SG, Erard F, Le Bert M, Quesniaux V, Ryffel B. Inflammasome-IL-1-Th17 response in allergic lung inflammation. Journal of Molecular Cell Biology. 4: 3-10. PMID 22147847 DOI: 10.1093/Jmcb/Mjr042  0.843
2012 Lan Q, Fan H, Quesniaux V, Ryffel B, Liu Z, Zheng SG. Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? Journal of Molecular Cell Biology. 4: 22-8. PMID 22107826 DOI: 10.1093/Jmcb/Mjr039  0.682
2012 Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis and Rheumatism. 64: 474-84. PMID 21952942 DOI: 10.1002/Art.33355  0.569
2012 Olleros M, Vesin D, Bisig R, Drutskaya M, Kruglov A, Quesniaux V, Ryffel B, Nedospasov S, Garcia I. P012 Control of mycobacterial infection in “humanized” TNF knock-in mice Cytokine. 59: 522. DOI: 10.1016/J.Cyto.2012.06.095  0.672
2012 Bourigault M, Vacher R, Rose S, Olleros M, Ryffel B, Quesniaux V, Garcia I. P011 TNF inhibition combined with chemotherapy for experimental tuberculosis improves pulmonary bacterial clearance and reduces pathology Cytokine. 59: 522. DOI: 10.1016/J.Cyto.2012.06.094  0.599
2011 Fagundes CT, Costa VV, Cisalpino D, Amaral FA, Souza PR, Souza RS, Ryffel B, Vieira LQ, Silva TA, Atrasheuskaya A, Ignatyev G, Sousa LP, Souza DG, Teixeira MM. IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner. Plos Neglected Tropical Diseases. 5: e1449. PMID 22206036 DOI: 10.1371/Journal.Pntd.0001449  0.499
2011 Conforti-Andreoni C, Spreafico R, Qian HL, Riteau N, Ryffel B, Ricciardi-Castagnoli P, Mortellaro A. Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18. Journal of Immunology (Baltimore, Md. : 1950). 187: 5842-50. PMID 22058415 DOI: 10.4049/Jimmunol.1101408  0.792
2011 Olagnier D, Lavergne RA, Meunier E, Lefèvre L, Dardenne C, Aubouy A, Benoit-Vical F, Ryffel B, Coste A, Berry A, Pipy B. Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria. Plos Pathogens. 7: e1002254. PMID 21949655 DOI: 10.1371/Journal.Ppat.1002254  0.354
2011 Lu L, Ma J, Li Z, Lan Q, Chen M, Liu Y, Xia Z, Wang J, Han Y, Shi W, Quesniaux V, Ryffel B, Brand D, Li B, Liu Z, et al. All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus. Plos One. 6: e24590. PMID 21931768 DOI: 10.1371/Journal.Pone.0024590  0.65
2011 Front S, Court N, Bourigault ML, Rose S, Ryffel B, Erard F, Quesniaux VF, Martin OR. Phosphatidyl myo-inositol mannosides mimics built on an acyclic or heterocyclic core: synthesis and anti-inflammatory properties. Chemmedchem. 6: 2081-93. PMID 21901834 DOI: 10.1002/Cmdc.201100291  0.576
2011 Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, di Padova F, Fick L, Charron S, Lagente V, Eberl G, Le Bert M, Quesniaux VF, Huaux F, Leite-de-Moraes M, Ryffel B, et al. IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis. Plos One. 6: e23185. PMID 21858022 DOI: 10.1371/Journal.Pone.0023185  0.832
2011 Renneson J, Guabiraba R, Maillet I, Marques RE, Ivanov S, Fontaine J, Paget C, Quesniaux V, Faveeuw C, Ryffel B, Teixeira MM, Trottein F. A detrimental role for invariant natural killer T cells in the pathogenesis of experimental dengue virus infection. The American Journal of Pathology. 179: 1872-83. PMID 21843496 DOI: 10.1016/J.Ajpath.2011.06.023  0.634
2011 Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, Viaud S, Ryffel B, Yagita H, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, et al. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Research. 71: 5393-9. PMID 21724589 DOI: 10.1158/0008-5472.Can-11-0993  0.448
2011 Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B. IL-33-activated dendritic cells are critical for allergic airway inflammation. European Journal of Immunology. 41: 1675-86. PMID 21469105 DOI: 10.1002/Eji.201041033  0.847
2011 Besnard AG, Guillou N, Tschopp J, Erard F, Couillin I, Iwakura Y, Quesniaux V, Ryffel B, Togbe D. NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant. Allergy. 66: 1047-57. PMID 21443539 DOI: 10.1111/J.1398-9995.2011.02586.X  0.665
2011 Secher T, Fauconnier L, Szade A, Rutschi O, Fas SC, Ryffel B, Rudolf MP. Anti-Pseudomonas aeruginosa serotype O11 LPS immunoglobulin M monoclonal antibody panobacumab (KBPA101) confers protection in a murine model of acute lung infection. The Journal of Antimicrobial Chemotherapy. 66: 1100-9. PMID 21393169 DOI: 10.1093/Jac/Dkr038  0.435
2011 Maillet I, Schnyder-Candrian S, Couillin I, Quesniaux VF, Erard F, Moser R, Fleury S, Kanda A, Dombrowicz D, Szymkowski DE, Ryffel B. Allergic lung inflammation is mediated by soluble tumor necrosis factor (TNF) and attenuated by dominant-negative TNF biologics. American Journal of Respiratory Cell and Molecular Biology. 45: 731-9. PMID 21297077 DOI: 10.1165/Rcmb.2010-0512Oc  0.68
2011 Besnard AG, Sabat R, Dumoutier L, Renauld JC, Willart M, Lambrecht B, Teixeira MM, Charron S, Fick L, Erard F, Warszawska K, Wolk K, Quesniaux V, Ryffel B, Togbe D. Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. American Journal of Respiratory and Critical Care Medicine. 183: 1153-63. PMID 21297073 DOI: 10.1164/Rccm.201008-1383Oc  0.835
2011 Fauconnier M, Bourigault ML, Meme S, Szeremeta F, Palomo J, Danneels A, Charron S, Fick L, Jacobs M, Beloeil JC, Ryffel B, Quesniaux VF. Protein kinase C-theta is required for development of experimental cerebral malaria. The American Journal of Pathology. 178: 212-21. PMID 21224058 DOI: 10.1016/J.Ajpath.2010.11.008  0.801
2011 Doisne JM, Soulard V, Bécourt C, Amniai L, Henrot P, Havenar-Daughton C, Blanchet C, Zitvogel L, Ryffel B, Cavaillon JM, Marie JC, Couillin I, Benlagha K. Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. Journal of Immunology (Baltimore, Md. : 1950). 186: 662-6. PMID 21169541 DOI: 10.4049/Jimmunol.1002725  0.486
2011 Garcia I, Olleros ML, Quesniaux VF, Jacobs M, Allie N, Nedospasov SA, Szymkowski DE, Ryffel B. Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection. Advances in Experimental Medicine and Biology. 691: 187-201. PMID 21153323 DOI: 10.1007/978-1-4419-6612-4_20  0.631
2010 Guabiraba R, Marques RE, Besnard AG, Fagundes CT, Souza DG, Ryffel B, Teixeira MM. Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice. Plos One. 5: e15680. PMID 21206747 DOI: 10.1371/Journal.Pone.0015680  0.805
2010 Allie N, Keeton R, Court N, Abel B, Fick L, Vasseur V, Vacher R, Olleros ML, Drutskaya MS, Guler R, Nedospasov SA, Garcia I, Ryffel B, Quesniaux VF, Jacobs M. Limited role for lymphotoxin α in the host immune response to Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 185: 4292-301. PMID 20817877 DOI: 10.4049/Jimmunol.1000650  0.661
2010 Kirstein F, Horsnell WG, Nieuwenhuizen N, Ryffel B, Lopata AL, Brombacher F. Anisakis pegreffii-induced airway hyperresponsiveness is mediated by gamma interferon in the absence of interleukin-4 receptor alpha responsiveness. Infection and Immunity. 78: 4077-86. PMID 20605987 DOI: 10.1128/Iai.01131-09  0.528
2010 Guiton R, Vasseur V, Charron S, Arias MT, Van Langendonck N, Buzoni-Gatel D, Ryffel B, Dimier-Poisson I. Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice. The Journal of Infectious Diseases. 202: 427-35. PMID 20575661 DOI: 10.1086/653738  0.548
2010 Van Maele L, Carnoy C, Cayet D, Songhet P, Dumoutier L, Ferrero I, Janot L, Erard F, Bertout J, Leger H, Sebbane F, Benecke A, Renauld JC, Hardt WD, Ryffel B, et al. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. Journal of Immunology (Baltimore, Md. : 1950). 185: 1177-85. PMID 20566828 DOI: 10.4049/Jimmunol.1000115  0.837
2010 Riteau N, Gasse P, Fauconnier L, Gombault A, Couegnat M, Fick L, Kanellopoulos J, Quesniaux VF, Marchand-Adam S, Crestani B, Ryffel B, Couillin I. Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis. American Journal of Respiratory and Critical Care Medicine. 182: 774-83. PMID 20522787 DOI: 10.1164/Rccm.201003-0359Oc  0.784
2010 Giordano G, van den Brûle S, Lo Re S, Triqueneaux P, Uwambayinema F, Yakoub Y, Couillin I, Ryffel B, Michiels T, Renauld JC, Lison D, Huaux F. Type I interferon signaling contributes to chronic inflammation in a murine model of silicosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 682-92. PMID 20513754 DOI: 10.1093/Toxsci/Kfq158  0.433
2010 Torres D, Dieudonné A, Ryffel B, Vilain E, Si-Tahar M, Pichavant M, Lassalle P, Trottein F, Gosset P. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 451-9. PMID 20505141 DOI: 10.4049/Jimmunol.0902833  0.491
2010 Foureau DM, Mielcarz DW, Menard LC, Schulthess J, Werts C, Vasseur V, Ryffel B, Kasper LH, Buzoni-Gatel D. TLR9-dependent induction of intestinal alpha-defensins by Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 184: 7022-9. PMID 20488791 DOI: 10.4049/Jimmunol.0901642  0.424
2010 Court N, Vasseur V, Vacher R, Frémond C, Shebzukhov Y, Yeremeev VV, Maillet I, Nedospasov SA, Gordon S, Fallon PG, Suzuki H, Ryffel B, Quesniaux VF. Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 7057-70. PMID 20488784 DOI: 10.4049/Jimmunol.1000164  0.643
2010 Bsibsi M, Bajramovic JJ, Vogt MH, van Duijvenvoorden E, Baghat A, Persoon-Deen C, Tielen F, Verbeek R, Huitinga I, Ryffel B, Kros A, Gerritsen WH, Amor S, van Noort JM. The microtubule regulator stathmin is an endogenous protein agonist for TLR3. Journal of Immunology (Baltimore, Md. : 1950). 184: 6929-37. PMID 20483774 DOI: 10.4049/Jimmunol.0902419  0.344
2010 Quesniaux VF, Jacobs M, Allie N, Grivennikov S, Nedospasov SA, Garcia I, Olleros ML, Shebzukhov Y, Kuprash D, Vasseur V, Rose S, Court N, Vacher R, Ryffel B. TNF in host resistance to tuberculosis infection. Current Directions in Autoimmunity. 11: 157-79. PMID 20173394 DOI: 10.1159/000289204  0.626
2010 Soares AL, Coelho FR, Guabiraba R, Kamal M, Vargaftig BB, Li L, Li J, Tavares-de-Lima W, Ryffel B. Tumor necrosis factor is not associated with intestinal ischemia/reperfusion-induced lung inflammation. Shock (Augusta, Ga.). 34: 306-13. PMID 20160673 DOI: 10.1097/Shk.0B013E3181Cdc585  0.459
2010 Secher T, Gaillot O, Ryffel B, Chamaillard M. Remote control of intestinal tumorigenesis by innate immunity. Cancer Research. 70: 1749-52. PMID 20145153 DOI: 10.1158/0008-5472.Can-09-3401  0.347
2010 Couper KN, Barnes T, Hafalla JC, Combes V, Ryffel B, Secher T, Grau GE, Riley EM, de Souza JB. Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. Plos Pathogens. 6: e1000744. PMID 20126448 DOI: 10.1371/Journal.Ppat.1000744  0.48
2010 Quesniaux V, Erard F, Ryffel B. Adjuvant activity on murine and human macrophages. Methods in Molecular Biology (Clifton, N.J.). 626: 117-30. PMID 20099125 DOI: 10.1007/978-1-60761-585-9_9  0.624
2010 Chalmin F, Ladoire S, Mignot G, Vincent J, Bruchard M, Remy-Martin JP, Boireau W, Rouleau A, Simon B, Lanneau D, De Thonel A, Multhoff G, Hamman A, Martin F, Chauffert B, ... ... Ryffel B, et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. The Journal of Clinical Investigation. 120: 457-71. PMID 20093776 DOI: 10.1172/Jci40483  0.358
2010 Brattström A, Schapowal A, Kamal MA, Maillet I, Ryffel B, Moser R. The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 17: 551-6. PMID 20092989 DOI: 10.1016/J.Phymed.2009.11.003  0.317
2010 Victoni T, Coelho FR, Soares AL, de Freitas A, Secher T, Guabiraba R, Erard F, de Oliveira-Filho RM, Vargaftig BB, Lauvaux G, Kamal MA, Ryffel B, Moser R, Tavares-de-Lima W. Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway. Medical Microbiology and Immunology. 199: 35-42. PMID 19941004 DOI: 10.1007/S00430-009-0134-5  0.471
2010 Brattström A, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R. Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice. Phytotherapy Research : Ptr. 24: 680-5. PMID 19827027 DOI: 10.1002/Ptr.2972  0.324
2010 Secher T, Gironella M, Dessein R, Sans M, Garcia S, Tsicopoulos A, Peyrin-Biroulet L, Desreumaux P, Panes J, Dagorn J, Colombel J, Ryffel B, Iovanna JL, Chamaillard M. 847w PAP/Reg3β Triggers IL-17-Dependent Neutrophil Recruitment and Intestinal Inflammation Gastroenterology. 138: S-115. DOI: 10.1016/S0016-5085(10)60529-X  0.48
2010 Weston-Davies W, Ryffel B, Teixeira MM, Garcia CC, Russo RC, Tavares LP, Nunn M. Complement C5 inhibition attenuates lung inflammation in H1N1 influenza Molecular Immunology. 47: 2252-2252. DOI: 10.1016/J.Molimm.2010.05.164  0.438
2009 Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. Journal of Immunology (Baltimore, Md. : 1950). 183: 8195-202. PMID 20007584 DOI: 10.4049/Jimmunol.0803154  0.522
2009 Carlos D, Fremond C, Samarina A, Vasseur V, Maillet I, Ramos SG, Erard F, Quesniaux V, Ohtsu H, Silva CL, Faccioli LH, Ryffel B. Histamine plays an essential regulatory role in lung inflammation and protective immunity in the acute phase of Mycobacterium tuberculosis infection. Infection and Immunity. 77: 5359-68. PMID 19822651 DOI: 10.1128/Iai.01497-08  0.517
2009 Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Génin P, ... ... Ryffel B, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1Β-dependent adaptive immunity against tumors Nature Medicine. 15: 1170-1178. PMID 19767732 DOI: 10.1038/Nm.2028  0.459
2009 Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF. Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression. The Journal of Biological Chemistry. 284: 23187-96. PMID 19561082 DOI: 10.1074/Jbc.M109.037846  0.677
2009 De Trez C, Magez S, Akira S, Ryffel B, Carlier Y, Muraille E. iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice. Plos Pathogens. 5: e1000494. PMID 19557162 DOI: 10.1371/Journal.Ppat.1000494  0.493
2009 Ventura GM, Balloy V, Ramphal R, Khun H, Huerre M, Ryffel B, Plotkowski MC, Chignard M, Si-Tahar M. Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia. Journal of Immunology (Baltimore, Md. : 1950). 183: 670-6. PMID 19535624 DOI: 10.4049/Jimmunol.0801497  0.497
2009 Secher T, Vasseur V, Poisson DM, Mitchell JA, Cunha FQ, Alves-Filho JC, Ryffel B. Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7855-64. PMID 19494310 DOI: 10.4049/Jimmunol.0804008  0.447
2009 Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sônego F, Cunha FQ, Ryffel B. IL-17 receptor signaling is required to control polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7846-54. PMID 19494309 DOI: 10.4049/Jimmunol.0803039  0.542
2009 Carlos D, Frantz FG, Souza-Júnior DA, Jamur MC, Oliver C, Ramos SG, Quesniaux VF, Ryffel B, Silva CL, Bozza MT, Faccioli LH. TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection. Microbes and Infection / Institut Pasteur. 11: 770-8. PMID 19442756 DOI: 10.1016/J.Micinf.2009.04.025  0.696
2009 Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, Erard F. Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin European Journal of Immunology. 39: 1587-1596. PMID 19424969 DOI: 10.1002/Eji.200838907  0.825
2009 Kirson ED, Giladi M, Gurvich Z, Itzhaki A, Mordechovich D, Schneiderman RS, Wasserman Y, Ryffel B, Goldsher D, Palti Y. Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs. Clinical & Experimental Metastasis. 26: 633-40. PMID 19387848 DOI: 10.1007/S10585-009-9262-Y  0.303
2009 Olleros ML, Vesin D, Lambou AF, Janssens JP, Ryffel B, Rose S, Frémond C, Quesniaux VF, Szymkowski DE, Garcia I. Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis. The Journal of Infectious Diseases. 199: 1053-63. PMID 19222369 DOI: 10.1086/597204  0.611
2009 Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, Couillin I. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. American Journal of Respiratory and Critical Care Medicine. 179: 903-13. PMID 19218193 DOI: 10.1016/S0761-8425(08)75060-5  0.82
2009 Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, et al. Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis. Gut. 58: 771-6. PMID 19174417 DOI: 10.1136/Gut.2008.168443  0.324
2009 Paul-Clark MJ, McMaster SK, Sorrentino R, Sriskandan S, Bailey LK, Moreno L, Ryffel B, Quesniaux VF, Mitchell JA. Toll-like receptor 2 is essential for the sensing of oxidants during inflammation. American Journal of Respiratory and Critical Care Medicine. 179: 299-306. PMID 19011150 DOI: 10.1164/Rccm.200707-1019Oc  0.559
2009 Victoni T, Coelho FR, Soares AL, de Freitas A, Secher T, Guabiraba R, Erard F, de Oliveira-Filho RM, Vargaftig BB, Lauvaux G, Kamal MA, Ryffel B, Moser R, Tavares-de-Lima W. Erratum to: Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway Medical Microbiology and Immunology. 199: 43-43. DOI: 10.1007/S00430-009-0140-7  0.409
2008 Erard F, Ryffel B. Toll like receptor - potential drug targets in infectious disease. Infectious Disorders Drug Targets. 8: 221-31. PMID 19075797 DOI: 10.2174/187152608786734179  0.387
2008 Barkhuizen M, Magez S, Ryffel B, Brombacher F. Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection. The Journal of Infectious Diseases. 198: 1284-91. PMID 18816189 DOI: 10.1086/592048  0.491
2008 Pallandre JR, Krzewski K, Bedel R, Ryffel B, Caignard A, Rohrlich PS, Pivot X, Tiberghien P, Zitvogel L, Strominger JL, Borg C. Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation. Blood. 112: 4420-4. PMID 18682600 DOI: 10.1182/Blood-2007-12-126888  0.322
2008 Chaix J, Tessmer MS, Hoebe K, Fuséri N, Ryffel B, Dalod M, Alexopoulou L, Beutler B, Brossay L, Vivier E, Walzer T. Cutting edge: Priming of NK cells by IL-18. Journal of Immunology (Baltimore, Md. : 1950). 181: 1627-31. PMID 18641298 DOI: 10.4049/Jimmunol.181.3.1627  0.477
2008 Bortolatto J, Borducchi E, Rodriguez D, Keller AC, Faquim-Mauro E, Bortoluci KR, Mucida D, Gomes E, Christ A, Schnyder-Candrian S, Schnyder B, Ryffel B, Russo M. Toll-like receptor 4 agonists adsorbed to aluminium hydroxide adjuvant attenuate ovalbumin-specific allergic airway disease: role of MyD88 adaptor molecule and interleukin-12/interferon-gamma axis. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 38: 1668-79. PMID 18631348 DOI: 10.1111/J.1365-2222.2008.03036.X  0.432
2008 Togbe D, de Sousa PL, Fauconnier M, Boissay V, Fick L, Scheu S, Pfeffer K, Menard R, Grau GE, Doan BT, Beloeil JC, Renia L, Hansen AM, Ball HJ, Hunt NH, ... Ryffel B, et al. Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. Plos One. 3: e2608. PMID 18612394 DOI: 10.1371/Journal.Pone.0002608  0.744
2008 Allie N, Alexopoulou L, Quesniaux VJ, Fick L, Kranidioti K, Kollias G, Ryffel B, Jacobs M. Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection. Immunology. 125: 522-34. PMID 18544042 DOI: 10.1111/J.1365-2567.2008.02865.X  0.637
2008 Janot L, Secher T, Torres D, Maillet I, Pfeilschifter J, Quesniaux VF, Landmann R, Ryffel B, Erard F. CD14 works with toll-like receptor 2 to contribute to recognition and control of Listeria monocytogenes infection. The Journal of Infectious Diseases. 198: 115-24. PMID 18462086 DOI: 10.1086/588815  0.815
2008 Doz E, Noulin N, Boichot E, Guénon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. Journal of Immunology (Baltimore, Md. : 1950). 180: 1169-78. PMID 18178857 DOI: 10.4049/Jimmunol.180.2.1169  0.68
2008 Doz E, Ryffel B, Quesniaux VFJ, Couillin I. Response to Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent” The Journal of Immunology. 180: 5761.2-5761. DOI: 10.4049/Jimmunol.180.9.5761-A  0.649
2008 Ullrich E, Terme M, Aymeric L, Apetoh L, Chaput N, Ryffel B, Mackensen A, Schultze JL, Zitvogel L. IL-18 Elicited Suppressor NK Cells with Immunoregulatory Functions Blood. 112: 106-106. DOI: 10.1182/BLOOD.V112.11.106.106  0.324
2007 Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F. Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells. Immunology Letters. 116: 86-94. PMID 18166232 DOI: 10.1016/J.Imlet.2007.11.014  0.496
2007 Togbe D, Schnyder-Candrian S, Schnyder B, Doz E, Noulin N, Janot L, Secher T, Gasse P, Lima C, Coelho FR, Vasseur V, Erard F, Ryffel B, Couillin I, Moser R. Toll-like receptor and tumour necrosis factor dependent endotoxin-induced acute lung injury. International Journal of Experimental Pathology. 88: 387-91. PMID 18039275 DOI: 10.1111/J.1365-2613.2007.00566.X  0.843
2007 Mitchell JA, Ryffel B, Quesniaux VFJ, Cartwright N, Paul-Clark M. Role of pattern-recognition receptors in cardiovascular health and disease Biochemical Society Transactions. 35: 1449-1452. PMID 18031243 DOI: 10.1042/Bst0351449  0.361
2007 Vanhoutte F, Breuilh L, Fontaine J, Zouain CS, Mallevaey T, Vasseur V, Capron M, Goriely S, Faveeuw C, Ryffel B, Trottein F. Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology. Microbes and Infection. 9: 1606-13. PMID 18023390 DOI: 10.1016/J.Micinf.2007.09.013  0.433
2007 Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. The Journal of Clinical Investigation. 117: 3786-99. PMID 17992263 DOI: 10.1172/Jci32285  0.699
2007 Dambuza I, Allie N, Fick L, Johnston N, Fremond C, Mitchell J, Quesniaux VF, Ryffel B, Jacobs M. Efficacy of membrane TNF mediated host resistance is dependent on mycobacterial virulence. Tuberculosis (Edinburgh, Scotland). 88: 221-34. PMID 17950671 DOI: 10.1016/J.Tube.2007.08.011  0.499
2007 Paget C, Mallevaey T, Speak AO, Torres D, Fontaine J, Sheehan KC, Capron M, Ryffel B, Faveeuw C, Leite de Moraes M, Platt F, Trottein F. Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity. 27: 597-609. PMID 17950005 DOI: 10.1016/J.Immuni.2007.08.017  0.448
2007 Le Buanec H, Paturance S, Couillin I, Schnyder-Candrian S, Larcier P, Ryffel B, Bizzini B, Bensussan A, Burny A, Gallo R, Zagury D, Peltre G. Control of allergic reactions in mice by an active anti-murine IL-4 immunization. Vaccine. 25: 7206-16. PMID 17719148 DOI: 10.1016/J.VACCINE.2007.07.029  0.432
2007 Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1872-83. PMID 17641054 DOI: 10.4049/Jimmunol.179.3.1872  0.827
2007 Doz E, Rose S, Nigou J, Gilleron M, Puzo G, Erard F, Ryffel B, Quesniaux VF. Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan. The Journal of Biological Chemistry. 282: 26014-25. PMID 17617634 DOI: 10.1074/Jbc.M702690200  0.629
2007 Fremond CM, Togbe D, Doz E, Rose S, Vasseur V, Maillet I, Jacobs M, Ryffel B, Quesniaux VF. IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1178-89. PMID 17617611 DOI: 10.4049/Jimmunol.179.2.1178  0.713
2007 Mockey M, Bourseau E, Chandrashekhar V, Chaudhuri A, Lafosse S, Le Cam E, Quesniaux VF, Ryffel B, Pichon C, Midoux P. mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes. Cancer Gene Therapy. 14: 802-14. PMID 17589432 DOI: 10.1038/Sj.Cgt.7701072  0.535
2007 Togbe D, Schofield L, Grau GE, Schnyder B, Boissay V, Charron S, Rose S, Beutler B, Quesniaux VF, Ryffel B. Murine cerebral malaria development is independent of toll-like receptor signaling. The American Journal of Pathology. 170: 1640-8. PMID 17456769 DOI: 10.2353/Ajpath.2007.060889  0.644
2007 Jacobs M, Togbe D, Fremond C, Samarina A, Allie N, Botha T, Carlos D, Parida SK, Grivennikov S, Nedospasov S, Monteiro A, Le Bert M, Quesniaux V, Ryffel B. Tumor necrosis factor is critical to control tuberculosis infection. Microbes and Infection. 9: 623-8. PMID 17409008 DOI: 10.1016/J.Micinf.2007.02.002  0.595
2007 Jacobs M, Samarina A, Grivennikov S, Botha T, Allie N, Fremond C, Togbe D, Vasseur V, Rose S, Erard F, Monteiro A, Quesniaux V, Ryffel B. Reactivation of tuberculosis by tumor necrosis factor neutralization. European Cytokine Network. 18: 5-13. PMID 17400533 DOI: 10.1684/Ecn.2007.0083  0.616
2007 Rad FH, Le Buanec H, Paturance S, Larcier P, Genne P, Ryffel B, Bensussan A, Bizzini B, Gallo RC, Zagury D, Uzan G. VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases. Proceedings of the National Academy of Sciences of the United States of America. 104: 2837-42. PMID 17301234 DOI: 10.1073/Pnas.0611022104  0.31
2007 Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VF, Evans TW, Thiemermann C, Mitchell JA. Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. American Journal of Respiratory and Critical Care Medicine. 175: 595-603. PMID 17234906 DOI: 10.1164/Rccm.200608-1103Oc  0.559
2007 Cartwright N, McMaster SK, Sorrentino R, Paul-Clark M, Sriskandan S, Ryffel B, Quesniaux VF, Evans TW, Mitchell JA. Elucidation of toll-like receptor and adapter protein signaling in vascular dysfunction induced by gram-positive Staphylococcus aureus or gram-negative Escherichia coli. Shock (Augusta, Ga.). 27: 40-7. PMID 17172979 DOI: 10.1097/01.Shk.0000235127.59492.Db  0.603
2007 Parida SK, Huygen K, Ryffel B, Chakraborty T. Novel bacterial delivery system with attenuated Salmonella typhimurium carrying plasmid encoding Mtb antigen 85A for mucosal immunization: establishment of proof of principle in TB mouse model. Annals of the New York Academy of Sciences. 1056: 366-78. PMID 16387702 DOI: 10.1196/Annals.1352.030  0.322
2007 Weston-Davies W, Couillin I, Schnyder S, Schnyder B, Moser R, Lissina O, Paesen GC, Nuttall P, Ryffel B. Arthropod-derived protein EV131 inhibits histamine action and allergic asthma. Annals of the New York Academy of Sciences. 1056: 189-96. PMID 16387687 DOI: 10.1196/Annals.1352.009  0.393
2007 Brattström A, Maillet I, Schnyder B, Moser R, Ryffel B. The anti-inflammatory extract from leaves of Isatis tinctoria (Ze 550) inhibits dose dependently the allergen induced airway-response in sensitized mice Planta Medica. 73. DOI: 10.1055/S-2007-987272  0.349
2006 Ryffel B, Jacobs M, Parida S, Botha T, Togbe D, Quesniaux V. Toll-like receptors and control of mycobacterial infection in mice. Novartis Foundation Symposium. 279: 127-39; discussion 1. PMID 17278391 DOI: 10.1002/9780470035399.Ch11  0.633
2006 Savoy F, Nicolle DM, Rivier D, Chiavaroli C, Ryffel B, Quesniaux VF. Synthetic triacylated lipid A derivative activates antigen presenting cells via the TLR4 pathway and promotes antigen-specific responses in vivo. Immunobiology. 211: 767-77. PMID 17113914 DOI: 10.1016/J.Imbio.2006.06.001  0.59
2006 Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B. Interleukin-17 is a negative regulator of established allergic asthma. The Journal of Experimental Medicine. 203: 2715-25. PMID 17101734 DOI: 10.1084/Jem.20061401  0.689
2006 Togbe D, Aurore G, Noulin N, Quesniaux VF, Schnyder-Candrian S, Schnyder B, Vasseur V, Akira S, Hoebe K, Beutler B, Ryffel B, Couillin I. Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1126-35. PMID 16983331 DOI: 10.1038/Labinvest.3700473  0.711
2006 Togbe D, Schnyder-Candrian S, Schnyder B, Couillin I, Maillet I, Bihl F, Malo D, Ryffel B, Quesniaux VFJ. TLR4 gene dosage contributes to endotoxin-induced acute respiratory inflammation Journal of Leukocyte Biology. 80: 451-457. PMID 16809643 DOI: 10.1189/Jlb.0206099  0.644
2006 Freeman S, Post FA, Bekker LG, Harbacheuski R, Steyn LM, Ryffel B, Connell ND, Kreiswirth BN, Kaplan G. Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro Journal of Interferon and Cytokine Research. 26: 27-33. PMID 16426145 DOI: 10.1089/Jir.2006.26.27  0.481
2006 Schnyder-Candrian S, Czarniecki J, Lerondel S, Corpataux J, Ryffel B, Schnyder B. Hepatic steatosis in the absence of tumor necrosis factor in mice. Cytokine. 32: 287-95. PMID 16406654 DOI: 10.1016/J.Cyto.2005.11.004  0.331
2006 Schnyder B, Schnyder-Candrian S, Pansky A, Schmitz ML, Heim M, Ryffel B, Moser R. IL-17 reduces TNF-induced Rantes and VCAM-1 expression. Cytokine. 31: 191-202. PMID 15975820 DOI: 10.1016/J.Cyto.2005.02.012  0.494
2005 Ryffel B, Couillin I, Maillet I, Schnyder B, Paesen GC, Nuttall P, Weston-Davies W. Histamine scavenging attenuates endotoxin-induced acute lung injury. Annals of the New York Academy of Sciences. 1056: 197-205. PMID 16387688 DOI: 10.1196/Annals.1352.034  0.369
2005 Torres D, Janot L, Quesniaux VF, Grivennikov SI, Maillet I, Sedgwick JD, Ryffel B, Erard F. Membrane tumor necrosis factor confers partial protection to Listeria infection. The American Journal of Pathology. 167: 1677-87. PMID 16314479 DOI: 10.1016/S0002-9440(10)61250-3  0.82
2005 Fremond C, Allie N, Dambuza I, Grivennikov SI, Yeremeev V, Quesniaux VF, Jacobs M, Ryffel B. Membrane TNF confers protection to acute mycobacterial infection. Respiratory Research. 6: 136. PMID 16285886 DOI: 10.1186/1465-9921-6-136  0.62
2005 Noulin N, Quesniaux VF, Schnyder-Candrian S, Schnyder B, Maillet I, Robert T, Vargaftig BB, Ryffel B, Couillin I. Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin. Journal of Immunology (Baltimore, Md. : 1950). 175: 6861-9. PMID 16272344 DOI: 10.4049/Jimmunol.175.10.6861  0.719
2005 Ryffel B, Fremond C, Jacobs M, Parida S, Botha T, Schnyder B, Quesniaux V. Innate immunity to mycobacterial infection in mice: critical role for toll-like receptors. Tuberculosis (Edinburgh, Scotland). 85: 395-405. PMID 16257265 DOI: 10.1016/J.Tube.2005.08.021  0.627
2005 Chege GK, Williamson AL, Passmore JS, Bourn W, Ryffel B, Shephard EG. The immune response of the Chacma baboon to Bacille Calmette Guerin: development of a primate model for BCG-based vaccine research. Vaccine. 23: 5783-91. PMID 16214269 DOI: 10.1016/J.Vaccine.2005.07.106  0.309
2005 Baratin M, Roetynck S, Lépolard C, Falk C, Sawadogo S, Uematsu S, Akira S, Ryffel B, Tiraby JG, Alexopoulou L, Kirschning CJ, Gysin J, Vivier E, Ugolini S. Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America. 102: 14747-52. PMID 16203971 DOI: 10.1073/Pnas.0507355102  0.467
2005 Drennan MB, Stijlemans B, Van den Abbeele J, Quesniaux VJ, Barkhuizen M, Brombacher F, De Baetselier P, Ryffel B, Magez S. The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent. Journal of Immunology (Baltimore, Md. : 1950). 175: 2501-9. PMID 16081822 DOI: 10.4049/Jimmunol.175.4.2501  0.647
2005 Schnyder-Candrian S, Quesniaux VF, Di Padova F, Maillet I, Noulin N, Couillin I, Moser R, Erard F, Vargaftig BB, Ryffel B, Schnyder B. Dual effects of p38 MAPK on TNF-dependent bronchoconstriction and TNF-independent neutrophil recruitment in lipopolysaccharide-induced acute respiratory distress syndrome. Journal of Immunology (Baltimore, Md. : 1950). 175: 262-9. PMID 15972657 DOI: 10.4049/Jimmunol.175.1.262  0.611
2005 Quesniaux V, Ryffel B. [Fatal tuberculosis despite adaptive immune response in the absence of MyD88]. Medecine Sciences : M/S. 21: 349-51. PMID 15811294 DOI: 10.1051/Medsci/2005214349  0.563
2005 Weber MA, Schnyder-Candrian S, Schnyder B, Quesniaux V, Poli V, Stewart CL, Ryffel B. Endogenous leukemia inhibitory factor attenuates endotoxin response. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 276-84. PMID 15702085 DOI: 10.1038/Labinvest.3700216  0.687
2005 Grivennikov SI, Tumanov AV, Liepinsh DJ, Kruglov AA, Marakusha BI, Shakhov AN, Murakami T, Drutskaya LN, Förster I, Clausen BE, Tessarollo L, Ryffel B, Kuprash DV, Nedospasov SA. Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects. Immunity. 22: 93-104. PMID 15664162 DOI: 10.1016/J.Immuni.2004.11.016  0.42
2005 Brown N, Jacobs M, Parida SK, Botha T, Santos A, Pick L, Gicquel B, Jackson M, Quesniaux V, Ryffel B. Reduced local growth and spread but preserved pathogenicity of a ΔpurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection Infection and Immunity. 73: 666-670. PMID 15618214 DOI: 10.1128/Iai.73.1.666-670.2005  0.591
2005 Koch F, Ivarsson L, Janke K, Stoitzner P, Ryffel B, Eugster HP, Romani N. Development and maturation of Langerhans cells, spleen and bone marrow dendritic cells in TNF-alpha/lymphotoxin-alpha double-deficient mice. Immunology Letters. 96: 109-20. PMID 15585314 DOI: 10.1016/J.Imlet.2004.08.007  0.371
2004 Fremond CM, Yeremeev V, Nicolle DM, Jacobs M, Quesniaux VF, Ryffel B. Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. The Journal of Clinical Investigation. 114: 1790-9. PMID 15599404 DOI: 10.1172/Jci200421027  0.68
2004 Nicolle D, Fremond C, Pichon X, Bouchot A, Maillet I, Ryffel B, Quesniaux VJ. Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice. Infection and Immunity. 72: 6994-7004. PMID 15557622 DOI: 10.1128/Iai.72.12.6994-7004.2004  0.63
2004 Couillin I, Maillet I, Vargaftig BB, Jacobs M, Paesen GC, Nuttall PA, Lefort J, Moser R, Weston-Davies W, Ryffel B. Arthropod-derived histamine-binding protein prevents murine allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 173: 3281-6. PMID 15322190 DOI: 10.4049/Jimmunol.173.5.3281  0.376
2004 Quesniaux V, Fremond C, Jacobs M, Parida S, Nicolle D, Yeremeev V, Bihl F, Erard F, Botha T, Drennan M, Soler MN, Le Bert M, Schnyder B, Ryffel B. Toll-like receptor pathways in the immune responses to mycobacteria. Microbes and Infection. 6: 946-59. PMID 15310472 DOI: 10.1016/J.Micinf.2004.04.016  0.602
2004 Nicolle DM, Pichon X, Bouchot A, Maillet I, Erard F, Akira S, Ryffel B, Quesniaux VF. Chronic pneumonia despite adaptive immune response to Mycobacterium bovis BCG in MyD88-deficient mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 1305-21. PMID 15258598 DOI: 10.1038/Labinvest.3700149  0.684
2004 Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood. 104: 3267-75. PMID 15242871 DOI: 10.1182/Blood-2004-01-0380  0.385
2004 Torres D, Barrier M, Bihl F, Quesniaux VJ, Maillet I, Akira S, Ryffel B, Erard F. Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection. Infection and Immunity. 72: 2131-9. PMID 15039335 DOI: 10.1128/Iai.72.4.2131-2139.2004  0.651
2004 Quesniaux VJ, Nicolle DM, Torres D, Kremer L, Guérardel Y, Nigou J, Puzo G, Erard F, Ryffel B. Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans. Journal of Immunology (Baltimore, Md. : 1950). 172: 4425-34. PMID 15034058 DOI: 10.4049/Jimmunol.172.7.4425  0.659
2004 Drennan MB, Nicolle D, Quesniaux VJ, Jacobs M, Allie N, Mpagi J, Frémond C, Wagner H, Kirschning C, Ryffel B. Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. The American Journal of Pathology. 164: 49-57. PMID 14695318 DOI: 10.1016/S0002-9440(10)63095-7  0.666
2004 Quesniaux VF, Ryffel B. Toll-like receptors: emerging targets of immunomodulation Expert Opinion On Therapeutic Patents. 14: 85-100. DOI: 10.1517/13543776.14.1.85  0.386
2003 Botha T, Ryffel B. Reactivation of latent tuberculosis infection in TNF-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 3110-8. PMID 12960337 DOI: 10.4049/jimmunol.171.6.3110  0.378
2003 Bihl F, Salez L, Beaubier M, Torres D, Larivière L, Laroche L, Benedetto A, Martel D, Lapointe JM, Ryffel B, Malo D. Overexpression of toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice Journal of Immunology. 170: 6141-6150. PMID 12794144 DOI: 10.4049/Jimmunol.170.12.6141  0.419
2003 Jacobs M, Fick L, Allie N, Brown N, Ryffel B. Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice. Clinical Chemistry and Laboratory Medicine. 40: 893-902. PMID 12435106 DOI: 10.1515/Cclm.2002.158  0.551
2002 Botha T, Ryffel B. Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model. Immunology. 107: 350-7. PMID 12423311 DOI: 10.1046/J.1365-2567.2002.01511.X  0.364
2002 Abel B, Thieblemont N, Quesniaux VJ, Brown N, Mpagi J, Miyake K, Bihl F, Ryffel B. Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 3155-62. PMID 12218133 DOI: 10.4049/Jimmunol.169.6.3155  0.658
2001 Post FA, Manca C, Neyrolles O, Ryffel B, Young DB, Kaplan G. Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Mycobacterium smegmatis-Induced Cytokine Production by Human Macrophages In Vitro Infection and Immunity. 69: 1433-1439. PMID 11179309 DOI: 10.1128/Iai.69.3.1433-1439.2001  0.417
2001 Le Hir M, Ryffel B, Schatzmann U. IL-12-dependent, INF-gamma-independent experimental glomerulonephritis. Kidney & Blood Pressure Research. 24: 27-32. PMID 11174003 DOI: 10.1159/000054202  0.415
2001 Moser R, Quesniaux V, Ryffel B. Use of transgenic animals to investigate drug hypersensitivity. Toxicology. 158: 75-83. PMID 11164996 DOI: 10.1016/S0300-483X(00)00411-X  0.509
2000 Garcia I, Guler R, Vesin D, Olleros ML, Vassalli P, Chvatchko Y, Jacobs M, Ryffel B. Lethal Mycobacterium bovis Bacillus Calmette Guérin infection in nitric oxide synthase 2-deficient mice: cell-mediated immunity requires nitric oxide synthase 2. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 1385-97. PMID 11005207 DOI: 10.1038/Labinvest.3780146  0.504
2000 Jacobs M, Brown N, Allie N, Gulert R, Ryffel B. Increased resistance to mycobacterial infection in the absence of interleukin-10. Immunology. 100: 494-501. PMID 10929077 DOI: 10.1046/J.1365-2567.2000.00053.X  0.481
2000 Jacobs M, Marino MW, Brown N, Abel B, Bekker LG, Quesniaux VJ, Fick L, Ryffel B. Correction of defective host response to Mycobacterium bovis BCG infection in TNF-deficient mice by bone marrow transplantation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 901-14. PMID 10879741 DOI: 10.1038/Labinvest.3780094  0.663
2000 Jacobs M, Brown N, Allie N, Chetty K, Ryffel B. Tumor necrosis factor receptor 2 plays a minor role for mycobacterial immunity. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 68: 68-75. PMID 10878503 DOI: 10.1159/000028116  0.427
2000 Hölscher C, Mohrs M, Dai WJ, Köhler G, Ryffel B, Schaub GA, Mossmann H, Brombacher F. Tumor necrosis factor alpha-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient mice. Infection and Immunity. 68: 4075-4083. PMID 10858224 DOI: 10.1128/Iai.68.7.4075-4083.2000  0.509
2000 Jacobs M, Brown N, Allie N, Ryffel B. Fatal Mycobacterium bovis BCG infection in TNF-LT-α-deficient mice Clinical Immunology. 94: 192-199. PMID 10692238 DOI: 10.1006/Clim.2000.4835  0.428
1999 Favre N, Da Laperousaz C, Ryffel B, Weiss NA, Imhof BA, Rudin W, Lucas R, Piguet PF. Role of ICAM-1 (CD54) in the development of murine cerebral malaria. Microbes and Infection / Institut Pasteur. 1: 961-8. PMID 10617927 DOI: 10.1016/S1286-4579(99)80513-9  0.435
1999 Ryffel B, Eugster H, Haas C, Le Hir M. Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice. International Journal of Experimental Pathology. 79: 453-60. PMID 10319026 DOI: 10.1046/J.1365-2613.1998.00080.X  0.393
1999 Favre N, Ryffel B, Rudin W. Parasite killing in murine malaria does not require nitric oxide production. Parasitology. 118: 139-43. PMID 10028527 DOI: 10.1017/S0031182098003618  0.347
1999 Favre N, Ryffel B, Rudin W. The development of murine cerebral malaria does not require nitric oxide production. Parasitology. 118: 135-8. PMID 10028526 DOI: 10.1017/S0031182098003606  0.315
1999 Watanabe N, Akikusa B, Park SY, Ohno H, Fossati L, Vecchietti G, Gessner JE, Schmidt RE, Verbeek JS, Ryffel B, Iwamoto I, Izui S, Saito T. Mast Cells Induce Autoantibody-Mediated Vasculitis Syndrome Through Tumor Necrosis Factor Production Upon Triggering Fcγ Receptors Blood. 94: 3855-3863. DOI: 10.1182/Blood.V94.11.3855.423K36_3855_3863  0.431
1999 Stoitzner P, Zanella M, Ortner U, Lukas M, Tagwerker A, Janke K, Lutz MB, Schuler G, Echtenacher B, Ryffel B, Koch F, Romani N. Migration of Langerhans cells and dermal dendritic cells in skin organ cultures: augmentation by TNF-α and IL-1 β Journal of Leukocyte Biology. 66: 462-470. DOI: 10.1002/Jlb.66.3.462  0.468
1998 Mencacci A, Cenci E, Del Sero G, Fè d'Ostiani C, Mosci P, Montagnoli C, Bacci A, Bistoni F, Quesniaux VF, Ryffel B, Romani L. Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. International Immunology. 10: 37-48. PMID 9488154 DOI: 10.1093/INTIMM/10.1.37  0.338
1998 Tkachuk M, Bolliger S, Ryffel B, Pluschke G, Banks TA, Herren S, Gisler RH, Kosco-Vilbois MH. Crucial role of tumor necrosis factor receptor 1 expression on nonhematopoietic cells for B cell localization within the splenic white pulp. The Journal of Experimental Medicine. 187: 469-77. PMID 9463397 DOI: 10.1084/Jem.187.4.469  0.349
1997 Favre N, Ryffel B, Bordmann G, Rudin W. The course of Plasmodium chabaudi chabaudi infections in interferon-gamma receptor deficient mice. Parasite Immunology. 19: 375-83. PMID 9292896 DOI: 10.1046/J.1365-3024.1997.D01-227.X  0.377
1997 Piguet PF, Kaufman S, Barazzone C, Muller M, Ryffel B, Eugster HP. Resistance of TNF/LT alpha double deficient mice to bleomycin-induced fibrosis. International Journal of Experimental Pathology. 78: 43-8. PMID 9166104 DOI: 10.1046/J.1365-2613.1997.D01-240.X  0.356
1997 Ryffel B. Impact of knockout mice in toxicology. Critical Reviews in Toxicology. 27: 135-54. PMID 9099516 DOI: 10.3109/10408449709021616  0.335
1997 Ryffel B. Interleukin-12: role of interferon-gamma in IL-12 adverse effects. Clinical Immunology and Immunopathology. 83: 18-20. PMID 9073529 DOI: 10.1006/clin.1996.4306  0.393
1997 Erb KJ, Rüger B, von Brevern M, Ryffel B, Schimpl A, Rivett K. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. The Journal of Experimental Medicine. 185: 329-39. PMID 9016881 DOI: 10.1084/Jem.185.2.329  0.505
1996 Eugster HP, Muller M, Karrer U, Car BD, Schnyder B, Eng VM, Woerly G, Le Hir M, di Padova F, Aguet M, Zinkernagel R, Bluethmann H, Ryffel B. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. International Immunology. 8: 23-36. PMID 8671586 DOI: 10.1093/Intimm/8.1.23  0.307
1996 Haas C, Ryffel B, Aguet M, Le Hir M. MHC antigens in interferon gamma (IFN gamma) receptor deficient mice: IFN gamma-dependent up-regulation of MHC class II in renal tubules. Kidney International. 48: 1721-7. PMID 8587232 DOI: 10.1038/Ki.1995.470  0.338
1994 Besemer J, Schnitzel W, Monschein U, Ryffel B. Cross-linking of human neutrophil surface proteins to iodinated interleukin 8 or neutrophil activating peptide-2 results in at least four separable proteins. Cytokine. 5: 512-9. PMID 8142608 DOI: 10.1016/1043-4666(93)90043-5  0.311
1994 Lahm H, Schnyder B, Wyniger J, Borbenyi Z, Yilmaz A, Car BD, Fischer JR, Givel JC, Ryffel B. Growth inhibition of human colorectal-carcinoma cells by interleukin-4 and expression of functional interleukin-4 receptors. International Journal of Cancer. 59: 440-7. PMID 7927955 DOI: 10.1002/ijc.2910590325  0.344
1994 Kovarik J, Kuntz L, Ryffel B, Borel JF. The viable motheaten (me(v)) mouse - A new model for arthritis Journal of Autoimmunity. 7: 575-588. PMID 7840851 DOI: 10.1006/Jaut.1994.1042  0.342
1994 Ryffel B, Car B, Woerly G, Weber M, DiPadova F, Kammuller M, Klug S, Neubert R, Neubert D. Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate-- the marmoset Blood. 83: 2093-2102. DOI: 10.1182/blood.V83.8.2093.bloodjournal8382093  0.331
1993 Foxwell BMJ, Willcocks JL, Taylor-Fishwick DA, Kulig K, Ryffel B, Londei M. Inhibition of activation-induced changes in the structure of the T cell interleukin-7 receptor by cyclosporin A and FK506 European Journal of Immunology. 23: 85-89. PMID 7678231 DOI: 10.1002/Eji.1830230114  0.456
1992 Ryffel B, Woerly G, Quesniaux VF, Husi H, Foxwell BM. Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation. Biochemical Pharmacology. 43: 953-60. PMID 1554393 DOI: 10.1016/0006-2952(92)90598-D  0.607
1992 Foxwell BM, Woerly G, Husi H, Mackie A, Quesniaux VF, Hiestand PC, Wenger RM, Ryffel B. Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo. Biochimica Et Biophysica Acta. 1138: 115-21. PMID 1540657 DOI: 10.1016/0925-4439(92)90050-W  0.543
1990 Foxwell BMJ, Woerly G, Ryffel B. Inhibition of interleukin 4 receptor expression on human lymphoid cells by cyclosporin European Journal of Immunology. 20: 1185-1188. PMID 2141571 DOI: 10.1002/Eji.1830200536  0.46
1989 Foxwell BMJ, Woerly G, Ryffel B. Identification of interleukin 4 receptor-associated proteins and expression of both high- and low-affinity binding on human lymphoid cells. European Journal of Immunology. 19: 1637-1641. PMID 2529125 DOI: 10.1002/Eji.1830190918  0.445
1989 Foxwell BMJ, Taylor D, Greiner B, Mihatsch MJ, Olivieri V, Ryffel B. CorrigendumBiotinylated recombinant interleukin-2 a tool for research on the interleukin-2 receptor Journal of Immunological Methods. 117. DOI: 10.1016/0022-1759(89)90130-0  0.306
1988 Foxwell BM, Taylor D, Greiner B, Mihatsch MJ, Olivieri V, Ryffel B. Biotinylated recombinant interleukin-2. A tool for research on the interleukin-2 receptor. Journal of Immunological Methods. 113: 221-9. PMID 3262688 DOI: 10.1016/0022-1759(88)90335-3  0.377
1988 Foxwell B, Taylor D, Ryffel B. Comparison Of The Structure Of The Murine Interleukin 2 (Il 2) Receptor On Cytotoxic And Helper T Cell Lines By Chemical Cross-Linking Of 125I-Labeled Il 2 European Journal of Immunology. 18: 1515-1519. PMID 2973414 DOI: 10.1002/Eji.1830181007  0.417
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