Year |
Citation |
Score |
2022 |
Milton ME, Cavanagh J. The Biofilm Regulatory Network from Bacillus subtilis: A Structure-Function Analysis. Journal of Molecular Biology. 435: 167923. PMID 36535428 DOI: 10.1016/j.jmb.2022.167923 |
0.582 |
|
2022 |
Zeczycki TN, Milton ME, Jung D, Thompson RJ, Jaimes FE, Hondros AD, Palethorpe S, Melander C, Cavanagh J. 2-Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria. Biochemistry. PMID 36454711 DOI: 10.1021/acs.biochem.2c00560 |
0.579 |
|
2021 |
Palethorpe S, Farrow JM, Wells G, Milton ME, Actis LA, Cavanagh J, Pesci EC. regulates its stress responses via the BfmRS two-component regulatory system. Journal of Bacteriology. JB0049421. PMID 34871031 DOI: 10.1128/JB.00494-21 |
0.574 |
|
2021 |
Palethorpe S, Milton ME, Pesci EC, Cavanagh J. Structure of the Acinetobacter baumannii PmrA receiver domain and insights into clinical mutants affecting DNA-binding and promoting colistin resistance. Journal of Biochemistry. PMID 34585233 DOI: 10.1093/jb/mvab102 |
0.643 |
|
2020 |
Dean SN, Milton ME, Cavanagh J, van Hoek ML. Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production. Frontiers in Cellular and Infection Microbiology. 10: 82. PMID 32232010 DOI: 10.3389/fcimb.2020.00082 |
0.653 |
|
2019 |
Milton ME, Draughn GL, Bobay BG, Stowe SD, Olson AL, Feldmann EA, Thompson RJ, Myers KH, Santoro MT, Kearns DB, Cavanagh J. The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis. Journal of Molecular Biology. PMID 31493408 DOI: 10.1016/J.Jmb.2019.08.019 |
0.645 |
|
2018 |
Milton ME, Minrovic BM, Harris DL, Kang B, Jung D, Lewis CP, Thompson RJ, Melander RJ, Zeng D, Melander C, Cavanagh J. Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR fromand QseB fromspp. Frontiers in Molecular Biosciences. 5: 15. PMID 29487854 DOI: 10.3389/Fmolb.2018.00015 |
0.69 |
|
2018 |
Logan Draughn G, Milton ME, Feldmann EA, Bobay BG, Roth BM, Olson AL, Thompson RJ, Actis LA, Davies C, Cavanagh J. The structure of the biofilm-controlling response regulator BfmR from Acinetobacter baumannii reveals details of its DNA-binding mechanism. Journal of Molecular Biology. PMID 29438671 DOI: 10.1016/J.Jmb.2018.02.002 |
0.74 |
|
2018 |
Milton ME, Minrovic BM, Harris DL, Draughn GL, Kang B, Jung D, Lewis CP, Thompson RJ, Melander RJ, Zeng D, Melander C, Cavanagh J. Resensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators. F1000research. 7. DOI: 10.7490/F1000Research.1115407.1 |
0.665 |
|
2018 |
Milton ME, Minrovic BM, Harris DL, Kang B, Jung D, Lewis CP, Thompson RJ, Melander RJ, Zeng D, Melander C, and Cavanagh J. Re-sensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators: characterization and comparison of interactions between 2-aminoimidazoles and the response regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp. Frontiers in Molecular Biosciences. DOI: 10.3389/fmolb.2018.00015 |
0.432 |
|
2018 |
Draughn GL, Milton ME, Feldmann EA, Bobay BG, Roth BM, Olson AL, Thompson RJ, Actis LA, Davies C, and Cavanagh, J. The structure of the biofilm-controlling response regulator BfmR from Acinetobacter baumannii reveals details of its DNA-binding mechanism. Journal of Molecular Biology. DOI: 10.1016/j.jmb.2018.02.002 |
0.435 |
|
2017 |
Milton ME, Leigh Allen C, Feldmann EA, Bobay BG, Jung DK, Stephens MD, Melander RJ, Theisen KE, Zeng D, Thompson RJ, Melander C, Cavanagh J. Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds. Molecular Microbiology. PMID 28755524 DOI: 10.1111/Mmi.13759 |
0.731 |
|
2017 |
Cavanagh J, Melander CC, Lucas JL, Zeng D, Theisen KE, Kang B, Jung D, Thompson RJ, Feldmann EA, Draughn GL, Milton ME. Inhibition and dispersion of biofilms: targeting bacterial response regulators to resensitize multidrug resistant bacteria to antibiotics F1000research. 7. DOI: 10.7490/F1000Research.1115380.1 |
0.677 |
|
2016 |
Milton ME, Choe JY, Honzatko RB, Nelson SW. Crystal structure of the apicoplast DNA polymerase from Plasmodium falciparum: the first look at a plastidic A-family DNA polymerase. Journal of Molecular Biology. PMID 27487482 DOI: 10.1016/J.Jmb.2016.07.016 |
0.576 |
|
2016 |
Milton ME, Nelson SW. Replication and Maintenance of the Plasmodium falciparum Apicoplast Genome. Molecular and Biochemical Parasitology. PMID 27338018 DOI: 10.1016/J.Molbiopara.2016.06.006 |
0.539 |
|
2016 |
Milton M, Honzatko R, Nelson S. Crystal structure of the Plasmodium falciparum apicoplast DNA polymerase F1000research. 5. DOI: 10.7490/F1000Research.1111479.1 |
0.547 |
|
2016 |
Milton M, Nelson S. X-ray crystallography and high-throughput assay to identify inhibitors of the Plasmodium falciparum apicoplast DNA polymerase F1000research. 5. DOI: 10.7490/F1000Research.1111476.1 |
0.53 |
|
2016 |
Milton M, Parrot E, Singh R, Nelson S. Anti-malaria drug discovery: high-throughput assay to identify inhibitors of the Plasmodium falciparum apicoplast DNA polymerase F1000research. 5. DOI: 10.7490/F1000Research.1111468.1 |
0.524 |
|
2015 |
Milton ME, Choe JY, Honzatko RB, Nelson SW. Crystallization and preliminary X-ray analysis of the Plasmodium falciparum apicoplast DNA polymerase. Acta Crystallographica. Section F, Structural Biology Communications. 71: 333-7. PMID 25760711 DOI: 10.1107/S2053230X15002423 |
0.545 |
|
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