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Lawrence N. Tumey, Ph.D. - Publications

Affiliations: 
2001 Duke University, Durham, NC 
 2010-2017 Pfizer 
 2017- Pharmacy and Pharmaceutical Science State University of New York, Binghamton, Vestal, NY, United States 
Area:
Antibody Drug Conjugates
Website:
https://www.binghamton.edu/pharmacy-and-pharmaceutical-sciences/departments/pharmacy-practice/profile.html?id=ltumey
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Tumey LN, Li F, Rago B, Han X, Loganzo F, Musto S, Graziani EI, Puthenveetil S, Casavant J, Marquette K, Clark T, Bikker J, Bennett EM, Barletta F, Piche-Nicholas N, et al. Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates. The Aaps Journal. PMID 28439809 DOI: 10.1208/S12248-017-0083-7  0.314
2006 Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK. Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 50: 2178-84. PMID 16723580 DOI: 10.1128/Aac.00140-06  0.447
2003 Pirrung MC, Tumey LN, McClerren AL, Raetz CR. High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties. Journal of the American Chemical Society. 125: 1575-86. PMID 12568618 DOI: 10.1021/Ja0209114  0.467
2002 Pirrung MC, Tumey LN, Raetz CR, Jackman JE, Snehalatha K, McClerren AL, Fierke CA, Gantt SL, Rusche KM. Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. Journal of Medicinal Chemistry. 45: 4359-70. PMID 12213077 DOI: 10.1021/Jm020183V  0.479
2002 Pirrung MC, Park K, Tumey LN. (19)F-encoded combinatorial libraries: discovery of selective metal binding and catalytic peptoids. Journal of Combinatorial Chemistry. 4: 329-44. PMID 12099851 DOI: 10.1021/Cc010083V  0.452
2000 Pirrung MC, Tumey LN. Oxazoline synthesis from hydroxyamides by resin capture and ring-forming release. Journal of Combinatorial Chemistry. 2: 675-80. PMID 11126295  0.416
2000 Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O, Raetz CR. Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs. The Journal of Biological Chemistry. 275: 11002-9. PMID 10753902 DOI: 10.1074/Jbc.275.15.11002  0.473
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