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James M. Wilson, MD PhD - Publications

Affiliations: 
Pathology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Gene Therapy, Liver Disease, Immunology
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Year Citation  Score
2023 Greig JA, Martins KM, Breton C, Lamontagne RJ, Zhu Y, He Z, White J, Zhu JX, Chichester JA, Zheng Q, Zhang Z, Bell P, Wang L, Wilson JM. Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration. Nature Biotechnology. PMID 37932420 DOI: 10.1038/s41587-023-01974-7  0.326
2023 Kistner A, Chichester JA, Wang L, Calcedo R, Greig JA, Cardwell LN, Wright MC, Couthouis J, Sethi S, McIntosh BE, McKeever K, Wadsworth S, Wilson JM, Kakkis E, Sullivan BA. Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques. Gene Therapy. PMID 37833563 DOI: 10.1038/s41434-023-00423-z  0.342
2023 Hordeaux J, Ramezani A, Tuske S, Mehta N, Song C, Lynch A, Lupino K, Chichester JA, Buza EL, Dyer C, Yu H, Bell P, Weimer JM, Do H, Wilson JM. Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase. Frontiers in Immunology. 14: 1094279. PMID 37033976 DOI: 10.3389/fimmu.2023.1094279  0.348
2022 Greig JA, Breton C, Ashley SN, Martins KM, Gorsuch C, Chorazeczewski JK, Furmanak T, Smith MK, Zhu Y, Bell P, Shoop W, Li H, Smith J, Tomberlin G, Clark P, ... ... Wilson JM, et al. Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases. Human Gene Therapy. 33: 1174-1186. PMID 36375122 DOI: 10.1089/hum.2022.061  0.352
2022 Horiuchi M, Hinderer CJ, Greig JA, Dyer C, Buza EL, Bell P, Chichester JA, Hayashi PM, Yan H, Goode T, Wilson JM. Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors. Molecular Therapy. Methods & Clinical Development. 27: 272-280. PMID 36320416 DOI: 10.1016/j.omtm.2022.09.017  0.383
2022 Zabaleta N, Bhatt U, Hérate C, Maisonnasse P, Sanmiguel J, Diop C, Castore S, Estelien R, Li D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Pascal Q, Naninck T, Kahlaoui N, ... ... Wilson JM, et al. Durable immunogenicity, adaptation to emerging variants and low dose efficacy of AAV-based COVID19 platform in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35546782 DOI: 10.1016/j.ymthe.2022.05.007  0.777
2021 Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, ... ... Wilson JM, et al. An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates. Cell Host & Microbe. PMID 34428428 DOI: 10.1016/j.chom.2021.08.002  0.804
2021 Wang L, Muthuramu I, Somanathan S, Zhang H, Bell P, He Z, Yu H, Zhu Y, Tretiakova AP, Wilson JM. Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia. Molecular Therapy. Methods & Clinical Development. 22: 1-10. PMID 34258325 DOI: 10.1016/j.omtm.2021.04.017  0.325
2021 Wang L, Breton C, Warzecha CC, Bell P, Yan H, He Z, White J, Zhu Y, Li M, Buza EL, Jantz D, Wilson JM. Long-term Stable Reduction of Low-density Lipoprotein in Nonhuman Primates Following In Vivo Genome Editing of PCSK9. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33609733 DOI: 10.1016/j.ymthe.2021.02.020  0.312
2021 Zabaleta N, Dai W, Bhatt U, Chichester JA, Estelien R, Sanmiguel J, Michalson KT, Diop C, Maciorowski D, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, ... ... Wilson JM, et al. Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates. Biorxiv : the Preprint Server For Biology. PMID 33442684 DOI: 10.1101/2021.01.05.422952  0.783
2020 Hinderer C, Miller R, Dyer C, Johansson J, Bell P, Buza E, Wilson JM. Adeno-associated virus serotype 1-based gene therapy for FTD caused by GRN mutations. Annals of Clinical and Translational Neurology. PMID 32937039 DOI: 10.1002/Acn3.51165  0.393
2020 Hordeaux J, Buza EL, Dyer C, Goode T, Mitchell TW, Richman L, Denton N, Hinderer C, Katz N, Schmid R, Miller R, Choudhury GR, Horiuchi M, Nambiar K, Yan H, ... ... Wilson JM, et al. Adeno-Associated Virus-Induced Dorsal Root Ganglion Pathology. Human Gene Therapy. 31: 808-818. PMID 32845779 DOI: 10.1089/Hum.2020.167  0.354
2020 Giles AR, Calcedo R, Tretiakova AP, Wilson JM. Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity. Frontiers in Immunology. 11: 1135. PMID 32733434 DOI: 10.3389/Fimmu.2020.01135  0.358
2020 Wilson JM, Flotte TR. Moving forward after two deaths in a gene therapy trial of myotubular myopathy. Human Gene Therapy. PMID 32605399 DOI: 10.1089/Hum.2020.182  0.313
2020 Hinderer C, Katz N, Dyer C, Goode T, Johansson J, Bell P, Richman L, Buza E, Wilson JM. Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration. Molecular Therapy. Methods & Clinical Development. 17: 969-974. PMID 32420410 DOI: 10.1016/J.Omtm.2020.04.012  0.318
2020 Lock M, Wilson J, Sena-Esteves M, Gao G. Sensitive Determination of Infectious Titer of Recombinant Adeno-Associated Viruses (rAAVs) Using TCID End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2020: pdb.prot095653. PMID 32358050 DOI: 10.1101/Pdb.Prot095653  0.534
2020 Wang L, Yang Y, Breton C, Bell P, Li M, Zhang J, Che Y, Saveliev A, He Z, White J, Latshaw C, Xu C, McMenamin D, Yu H, Morizono H, ... ... Wilson JM, et al. A mutation-independent CRISPR-Cas9-mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency. Science Advances. 6: eaax5701. PMID 32095520 DOI: 10.1126/Sciadv.Aax5701  0.381
2020 Somanathan S, Calcedo R, Wilson JM. Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32035027 DOI: 10.1016/J.Ymthe.2020.01.006  0.346
2019 Lock M, Alvira M, Wilson J, Sena-Esteves M, Gao G. Detection Assay for Replication-Competent Adenovirus by Concentration Passage and Real-Time Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095588. PMID 31792138 DOI: 10.1101/Pdb.Prot095588  0.503
2019 Gupta V, Cadieux CL, McMenamin D, Medina-Jaszek CA, Arif M, Ahonkhai O, Wielechowski E, Taheri M, Che Y, Goode T, Limberis MP, Li M, Cerasoli DM, Tretiakova AP, Wilson JM. Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning. Plos One. 14: e0225188. PMID 31765413 DOI: 10.1371/Journal.Pone.0225188  0.469
2019 Ashley SN, Somanathan S, Giles AR, Wilson JM. TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy. Cellular Immunology. 346: 103997. PMID 31703913 DOI: 10.1016/J.Cellimm.2019.103997  0.41
2019 Mendell JR, Wilson JM. Breakthrough to Bedside: Bringing Gene Therapy to Neuromuscular Diseases. Human Gene Therapy. Clinical Development. PMID 31486676 DOI: 10.1089/Humc.2019.29049.Int  0.355
2019 Lock M, Korn M, Wilson J, Sena-Esteves M, Gao G. Preparation of a DNA Standard for Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095570. PMID 31371468 DOI: 10.1101/Pdb.Prot095570  0.378
2019 Lock M, Korn M, Wilson J, Sena-Esteves M, Gao G. Measuring the Infectious Titer of Recombinant Adenovirus Using Tissue Culture Infection Dose 50% (TCID) End-Point Dilution and Quantitative Polymerase Chain Reaction (qPCR). Cold Spring Harbor Protocols. 2019: pdb.prot095562. PMID 31371467 DOI: 10.1101/Pdb.Prot095562  0.457
2019 Wilson JM. Cycling at the Frontiers of Gene Therapy. Human Gene Therapy. Clinical Development. 30: 47-49. PMID 31215809 DOI: 10.1089/Humc.2019.29046.Int  0.343
2019 Hordeaux J, Hinderer C, Buza EL, Louboutin JP, Jahan T, Bell P, Chichester JA, Tarantal AF, Wilson JM. Safe and sustained expression of human iduronidase after adeno-associated virus 9 intrathecal administration in infant rhesus monkeys. Human Gene Therapy. PMID 31017018 DOI: 10.1089/Hum.2019.012  0.423
2019 Wang L, Yang Y, Breton CA, White J, Zhang J, Che Y, Saveliev A, McMenamin D, He Z, Latshaw C, Li M, Wilson JM. CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX knockout mice. Blood. PMID 30975639 DOI: 10.1182/Blood.2019000790  0.439
2019 Hordeaux J, Yuan Y, Clark PM, Wang Q, Martino RA, Sims JJ, Bell P, Raymond A, Stanford WL, Wilson JM. The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30819613 DOI: 10.1016/J.Ymthe.2019.02.013  0.4
2019 Greig J, Nordin J, Smith M, Ashley SN, Draper C, Zhu Y, Bell P, Buza EL, Wilson JM. A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease. Human Gene Therapy. Clinical Development. PMID 30693797 DOI: 10.1089/Humc.2018.219  0.363
2018 Wilson JM. Gene Therapy Entering the Land of Oz. Human Gene Therapy. Clinical Development. 29: 171. PMID 30576251 DOI: 10.1089/Humc.2018.29040.Wil  0.357
2018 Greig JA, Calcedo R, Kuri-Cervantes L, Nordin JML, Albrecht J, Bote E, Goode T, Chroscinski EA, Bell P, Richman LK, Betts MR, Wilson JM. AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver. Molecular Therapy. Methods & Clinical Development. 11: 191-201. PMID 30547050 DOI: 10.1016/J.Omtm.2018.10.012  0.433
2018 Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, ... ... Wilson JM, et al. Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science (New York, N.Y.). 362: 598-602. PMID 30385580 DOI: 10.1126/Science.Aaq0620  0.335
2018 Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, Wilson JM. Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30343890 DOI: 10.1016/J.Ymthe.2018.09.013  0.404
2018 Ashley SN, Nordin JML, Buza EL, Greig JA, Wilson JM. Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria. Molecular Genetics and Metabolism. PMID 30253962 DOI: 10.1016/J.Ymgme.2018.08.013  0.428
2018 Greig JA, Nordin JML, Draper C, McMenamin D, Chroscinski EA, Bell P, Gray JT, Richman LK, Wilson JM. Determining the Minimally Effective Dose of a Clinical Candidate AAV Vector in a Mouse Model of Crigler-Najjar Syndrome. Molecular Therapy. Methods & Clinical Development. 10: 237-244. PMID 30112420 DOI: 10.1016/J.Omtm.2018.07.008  0.364
2018 Giles AR, Govindasamy L, Somanathan S, Wilson JM. Mapping an adeno-associated virus 9-specific neutralizing epitope to develop next-generation gene delivery vectors. Journal of Virology. PMID 30089698 DOI: 10.1128/Jvi.01011-18  0.421
2018 Hordeaux J, Hinderer C, Goode T, Katz N, Buza EL, Bell P, Calcedo R, Richman LK, Wilson JM. Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Human Alpha-L-Iduronidase in Rhesus Macaques. Molecular Therapy. Methods & Clinical Development. 10: 79-88. PMID 30073179 DOI: 10.1016/J.Omtm.2018.06.003  0.383
2018 Hordeaux J, Hinderer C, Goode T, Buza EL, Bell P, Calcedo R, Richman LK, Wilson JM. Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Iduronate-2-Sulfatase in Rhesus Macaques. Molecular Therapy. Methods & Clinical Development. 10: 68-78. PMID 30073178 DOI: 10.1016/J.Omtm.2018.06.004  0.397
2018 Katz N, Goode T, Hinderer C, Hordeaux J, Wilson JM. Standardized method for intra-cisterna magna delivery under fluoroscopic guidance in nonhuman primates. Human Gene Therapy Methods. PMID 30032644 DOI: 10.1089/Hgtb.2018.041  0.302
2018 Wang L, Smith J, Breton C, Clark P, Zhang J, Ying L, Che Y, Lape J, Bell P, Calcedo R, Buza EL, Saveliev A, Bartsevich VV, He Z, White J, ... ... Wilson JM, et al. Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol. Nature Biotechnology. PMID 29985478 DOI: 10.1038/Nbt.4182  0.394
2018 Greig J, Nordin J, White J, Wang Q, Bote E, Goode T, Calcedo R, Wadsworth S, Wang L, Wilson JM. Optimized Adeno-Associated Virus-Mediated Human Factor VIII Gene Therapy in Cynomolgus Macaques. Human Gene Therapy. PMID 29890905 DOI: 10.1089/Hum.2018.080  0.463
2018 Calcedo R, Chichester JA, Wilson JM. Assessment of Humoral, Innate, and T-Cell Immune Responses to Adeno-Associated Virus Vectors. Human Gene Therapy Methods. 29: 86-95. PMID 29668327 DOI: 10.1089/Hum.2018.038  0.375
2018 Greig JA, Nordin JML, Draper C, Bell P, Wilson JM. AAV8 Gene Therapy Rescues the Newborn Phenotype of a Mouse Model of Crigler-Najjar. Human Gene Therapy. PMID 29448836 DOI: 10.1089/Hum.2017.185  0.384
2018 Hordeaux J, Wang Q, Katz N, Buza EL, Bell P, Wilson JM. The Neurotropic Properties of AAV-PHP.B Are Limited to C57BL/6J Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29428298 DOI: 10.1016/J.Ymthe.2018.01.018  0.37
2018 Hinderer C, Katz N, Buza EL, Dyer C, Goode T, Bell P, Richman L, Wilson JM. Severe toxicity in nonhuman primates and piglets following high-dose intravenous administration of an AAV vector expressing human SMN. Human Gene Therapy. PMID 29378426 DOI: 10.1089/Hum.2018.015  0.339
2017 Liu Y, Fortmann SD, Shen J, Wielechowski E, Tretiakova A, Yoo S, Kozarsky K, Wang J, Wilson JM, Campochiaro PA. AAV8-antiVEGFfab Ocular Gene Transfer for Neovascular Age-Related Macular Degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29292162 DOI: 10.1016/J.Ymthe.2017.12.002  0.36
2017 Flotte TR, Daniels E, Benson J, Bevett-Rose JM, Cornetta K, Diggins M, Johnston J, Sepelak S, Van Der Loo J, Wilson JM, McDonald CL. The Gene Therapy Resource Program: A Decade of Dedication to Translational Research by the National Heart, Lung, and Blood Institute. Human Gene Therapy. Clinical Development. PMID 29130351 DOI: 10.1089/Humc.2017.170  0.321
2017 Malherbe DC, Mendy J, Vang L, Barnette PT, Reed J, Lakhashe SK, Owuor J, Gach JS, Legasse AW, Axthelm MK, LaBranche CC, Montefiori D, Forthal DN, Park B, Wilson JM, et al. Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C SHIV Mucosal Challenge. Journal of Virology. PMID 29093095 DOI: 10.1128/Jvi.01092-17  0.32
2017 Hinderer C, Katz N, Louboutin JP, Bell P, Tolar J, Orchard PJ, Lund TC, Nayal M, Weng L, Mesaros C, de Souza CFM, Dalla Corte A, Giugliani R, Wilson JM. Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis. Human Molecular Genetics. 26: 3837-3849. PMID 28934395 DOI: 10.1093/Hmg/Ddx277  0.319
2017 Kapoor R, Klueter T, Wilson JM. Challenges in the gene therapy commercial ecosystem. Nature Biotechnology. 35: 813-815. PMID 28898227 DOI: 10.1038/Nbt.3931  0.363
2017 Hinderer C, Bell P, Katz N, Vite C, Louboutin JP, Bote E, Yu H, Zhu Y, Casal ML, Bagel J, O'Donnell P, Wang P, Haskins ME, Goode T, Wilson JM. Evaluation of intrathecal routes of administration for adeno-associated virus vectors in large animals. Human Gene Therapy. PMID 28806897 DOI: 10.1089/Hum.2017.026  0.402
2017 Wilson JM. The Past, Present, and Future of Gene Therapy from Nobel Laureate David Baltimore. Human Gene Therapy. Clinical Development. PMID 28530842 DOI: 10.1089/Humc.2017.29024.Int  0.359
2017 Ashley SN, Somanathan S, Hinderer C, Arias M, McMenamin D, Draper C, Wilson JM. Alternative Start Sites Downstream of Nonsense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28500077 DOI: 10.4049/Jimmunol.1601131  0.377
2017 Mueller C, Gernoux G, Gruntman AM, Borel F, Reeves EP, Calcedo R, Rouhani FN, Yachnis A, Humphries M, Campbell-Thompson M, Messina L, Chulay JD, Trapnell B, Wilson JM, McElvaney NG, et al. 5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28408179 DOI: 10.1016/J.Ymthe.2017.03.029  0.339
2017 Gernoux G, Wilson JM, Mueller C. Regulatory and exhausted T cell responses to AAV capsid. Human Gene Therapy. PMID 28323492 DOI: 10.1089/Hum.2017.022  0.416
2017 Greig JA, Limberis MP, Bell P, Chen SJ, Calcedo R, Rader DJ, Wilson JM. Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR(+/-) Rhesus Macaques. Human Gene Therapy. Clinical Development. 28: 39-50. PMID 28319449 DOI: 10.1089/Humc.2017.014  0.434
2017 Wang L, Bell P, Morizono H, He Z, Pumbo E, Yu H, White J, Batshaw ML, Wilson JM. AAV gene therapy corrects OTC deficiency and prevents liver fibrosis in aged OTC-knock out heterozygous mice. Molecular Genetics and Metabolism. PMID 28283349 DOI: 10.1016/J.Ymgme.2017.02.011  0.389
2017 Wilson JM. Jurassic Park, Gene Therapy, and Neuroscience. Human Gene Therapy. Clinical Development. PMID 28263671 DOI: 10.1089/Humc.2017.29022.Int  0.362
2017 Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM. Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137880 DOI: 10.1073/Pnas.1617726114  0.395
2017 Greig JA, Wang Q, Reicherter AL, Chen SJ, Hanlon AL, Tipper CH, Clark KR, Wadsworth S, Wang L, Wilson JM. Characterization of AAV-mediated human factor VIII gene therapy in hemophilia A mice. Human Gene Therapy. PMID 28056565 DOI: 10.1089/Hum.2016.128  0.407
2016 Greig JA, Nordin JM, Bote E, Makaron L, Garnett ME, Kattenhorn LM, Bell P, Goode T, Wilson JM. Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques. Molecular Therapy. Methods & Clinical Development. 3: 16079. PMID 27933307 DOI: 10.1038/Mtm.2016.79  0.39
2016 Bell P, Wang L, Chen SJ, Yu H, Zhu Y, Nayal M, He Z, White J, Lebel-Hagan D, Wilson JM. Effects of self-complementarity, codon optimization, transgene, and dose on liver transduction with AAV8. Human Gene Therapy Methods. PMID 27903094 DOI: 10.1089/Hgtb.2016.039  0.39
2016 Greig JA, Calcedo R, Grant RL, Peng H, Medina-Jaszek CA, Ahonkhai O, Qin Q, Roy S, Tretiakova AP, Wilson JM. Intramuscular administration of AAV overcomes pre-existing neutralizing antibodies in rhesus macaques. Vaccine. PMID 27817961 DOI: 10.1016/J.Vaccine.2016.10.053  0.463
2016 Limberis MP, Tretiakova A, Nambiar K, Wong G, Racine T, Crosariol M, Xiangguo Q, Kobinger G, Wilson JM. AAV9-expressed ZMapp in mice confers protection against systemic and airway-acquired Ebola virus infection. The Journal of Infectious Diseases. PMID 27683818 DOI: 10.1093/Infdis/Jiw460  0.386
2016 Hinderer C, Bell P, Louboutin JP, Katz N, Zhu Y, Lin G, Choa R, Bagel J, O'Donnell P, Fitzgerald CA, Langan T, Wang P, Casal ML, Haskins ME, Wilson JM. Neonatal tolerance induction enables accurate evaluation of gene therapy for MPS I in a canine model. Molecular Genetics and Metabolism. PMID 27386755 DOI: 10.1016/J.Ymgme.2016.06.006  0.424
2016 Calcedo R, Wilson JM. AAV Natural Infection Induces Broad Cross-Neutralizing Antibody Responses to Multiple AAV Serotypes in Chimpanzees. Human Gene Therapy. Clinical Development. 27: 79-82. PMID 27314914 DOI: 10.1089/Humc.2016.048  0.316
2016 Wilson JM. Recollections from a Pioneer Who Provided the Foundation for the Success of Gene Therapy in Treating Severe Combined Immune Deficiencies. Human Gene Therapy. Clinical Development. 27: 53-56. PMID 27314911 DOI: 10.1089/Humc.2016.29013.Int  0.369
2016 Yang Y, Wang L, Bell P, McMenamin D, He Z, White J, Yu H, Xu C, Morizono H, Musunuru K, Batshaw ML, Wilson JM. A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice. Nature Biotechnology. PMID 26829317 DOI: 10.1038/Nbt.3469  0.412
2016 Harrington EA, Sloan JL, Manoli I, Chandler RJ, Schneider M, McGuire PJ, Calcedo R, Wilson JM, Venditti CP. Neutralizing Antibodies against AAV Capsids in Patients with mut Methylmalonic Acidemia (MMA). Human Gene Therapy. PMID 26790480 DOI: 10.1089/Hum.2015.092  0.319
2016 Ibrahim S, Somanathan S, Billheimer J, Wilson JM, Rader DJ. Stable Liver-specific Expression of Human IDOL in Humanized Mice Raises Plasma Cholesterol. Cardiovascular Research. PMID 26786161 DOI: 10.1093/Cvr/Cvw010  0.343
2016 Wang L, Wilson JM, Calcedo R, Bell P, He Z, White J, Hewitt M, Makaron L, Kattenhorn L, Wadsworth S, Goode T. Strategies for Selection of AAV Vectors for Administration to Liver: Studies in Nonhuman Primates Blood. 128: 2316-2316. DOI: 10.1182/Blood.V128.22.2316.2316  0.322
2016 Wang L, Yang Y, White J, Deirdre M, Bell P, Wilson JM. Crispr/Cas9-Mediated In Vivo Gene Targeting Corrects Haemostasis in Newborn and Adult FIX-KO Mice Blood. 128: 1174-1174. DOI: 10.1182/Blood.V128.22.1174.1174  0.427
2016 Greig JA, Wang Q, Reicherter AL, Bote E, McMenamin D, Draper C, Chen S, Hanlon AL, Goode T, Clark KR, Wadsworth S, Wang L, Wilson JM. 760. Optimized AAV-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice and Cynomolgus Macaques Molecular Therapy. 24: S300. DOI: 10.1016/S1525-0016(16)33568-7  0.411
2016 Crosariol M, Stity G, Ahonkhai O, Wielechowski E, Medina-Jaszek AC, Sandhu A, Johnston J, Lock M, Tretiakova A, Wilson JM, Limberis MP. 699. Effective AAV9 Vector Delivery to Nasal Mucosa for Protection Against Airborne Challenge with Influenza A and B Molecular Therapy. 24: S276. DOI: 10.1016/S1525-0016(16)33507-9  0.389
2016 Ashley S, McMenamin D, Draper C, Wilson JM. 696. TLR9 Signaling Mediates Transgene Antibody Formation Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33504-3  0.412
2016 Wang Q, Bell P, Yu H, Draper C, McMenamin D, Limberis MP, Wilson JM. 695. An AAV8 Mutant with Better Transduction in Murine Muscle and Nasal Airway Than AAV8 Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33503-1  0.403
2016 Wang L, Yang Y, Bell P, McMenamin D, He Z, White J, Yu H, Xu C, Morizono H, Musunuru K, Batshaw ML, Wilson JM. 481. CRISPR/Cas9-Mediated In Vivo Genome Editing to Correct the OTC spfash Mutation in Newborn Mice Molecular Therapy. 24: S190-S191. DOI: 10.1016/S1525-0016(16)33290-7  0.44
2016 Hinderer C, Katz N, Louboutin J, Bell P, Yu H, Naval M, Kozarsky K, O'Brien T, Goode T, Wilson JM. 346. AAV9 Delivery into Cerebrospinal Fluid Corrects CNS Disease in a Murine Model of Mucopolysaccharidosis Type II Molecular Therapy. 24: S138-S139. DOI: 10.1016/S1525-0016(16)33155-0  0.372
2016 Wang L, White J, He Z, Goode T, McMenamin D, Draper C, Brown C, Chroscinski EA, Kattenhorn L, Wilmes G, Clark R, Wadsworth S, Wilson JM. 227. A Dose-Escalating Preclinical Study to Determine the Efficacy, MED, and Safety of a Clinical Candidate Vector in a Mouse Model of Hemophilia B Molecular Therapy. 24: S89. DOI: 10.1016/S1525-0016(16)33036-2  0.377
2016 Wielechowski E, Medina-Jaszek A, Ahonkhai O, Arif M, Bennett J, Maguire A, Tretiakova A, Wilson JM. 189. Therapeutic Gene Transfer as a Treatment Option for Age-Related Macular Degeneration Molecular Therapy. 24: S74. DOI: 10.1016/S1525-0016(16)32998-7  0.51
2016 Giles AR, Govindasamy L, Calcedo R, Tretiakova A, Boyd S, Qin Q, Schneider M, Wilson JM. 82. Mapping the Humoral Immune Response to AAV by Molecular Docking and Cryo-Electron Microscopy for the Design of Next-Generation AAV Vectors Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32891-X  0.341
2016 Medina-Jaszek A, Ahokhai O, Taheri M, Arif M, Tretiakova A, Wilson JM. 60. Engineering AAV Vector for the Delivery of Human BuChE to Protect Against Exposure to Organophosphates Molecular Therapy. 24: S26. DOI: 10.1016/S1525-0016(16)32869-6  0.418
2016 Mueller C, Chulay JD, McElvaney NG, Gernoux G, Reeves EP, Rouhani FN, Humphries M, Gruntman AM, Campbell-Thompson M, Wilson JM, Flotte TR. 24. Sustained Expression with Partial Correction of Neutrophil Defects 5 Years After Intramuscular rAAV1 Gene Therapy for Alpha-1 Antitrypsin Deficiency Molecular Therapy. 24: S11-S12. DOI: 10.1016/S1525-0016(16)32833-7  0.393
2016 Casal ML, Wang P, ODonnell PA, Sikora T, Langan T, O'Malley T, Ferla R, Auricchio A, Wilson JM, Gao G, Ponder K, Haskins ME. Urinary glycosaminoglycan concentration as a biomarker for effectiveness of enzyme replacement and gene therapy in large animal models of mucopolysaccharidoses Molecular Genetics and Metabolism. 117: S32. DOI: 10.1016/J.Ymgme.2015.12.214  0.622
2015 Mason JB, Gurda BL, Van Wettere A, Engiles JB, Wilson JM, Richardson DW. Delivery and evaluation of recombinant adeno-associated viral vectors in the equine distal extremity for the treatment of laminitis. Equine Veterinary Journal. PMID 26663470 DOI: 10.1111/Evj.12547  0.36
2015 Wang Q, Lock M, Prongay AJ, Alvira MR, Petkov B, Wilson JM. Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin. Molecular Therapy. Methods & Clinical Development. 2: 15040. PMID 26605372 DOI: 10.1038/Mtm.2015.40  0.354
2015 Gurda BL, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, Bagel J, Vite CH, Sikora T, Hinderer C, Calcedo R, Yox AD, Steet RA, Ruane T, O'Donnell P, ... ... Wilson JM, et al. Evaluation of AAV-mediated gene therapy for central nervous system disease in canine mucopolysaccharidosis VII. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26447927 DOI: 10.1038/Mt.2015.189  0.486
2015 Wang L, Bell P, Somanathan S, Wang Q, He Z, Yu H, McMenamin D, Goode T, Calcedo R, Wilson JM. Comparative Study of Liver Gene Transfer with AAV Vectors Based on Natural and Engineered AAV Capsids. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26412589 DOI: 10.1038/Mt.2015.179  0.471
2015 Huang J, Li X, Coelho-Dos-Reis JG, Zhang M, Mitchell R, Nogueira RT, Tsao T, Noe AR, Ayala R, Sahi V, Gutierrez GM, Nussenzweig V, Wilson JM, Nardin EH, Nussenzweig RS, et al. Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria. Journal of Immunological Methods. PMID 26410104 DOI: 10.1016/J.Jim.2015.09.005  0.335
2015 Wilson JM. Human Gene Therapy Clinical Development: Where the Academy and Industry Meet. Human Gene Therapy. Clinical Development. 26: 139. PMID 26390087 DOI: 10.1089/Humc.2015.29002.Wil  0.354
2015 Halder S, Van Vliet K, Smith JK, Duong TT, McKenna R, Wilson JM, Agbandje-McKenna M. Structure of neurotropic adeno-associated virus AAVrh.8. Journal of Structural Biology. PMID 26334681 DOI: 10.1016/J.Jsb.2015.08.017  0.351
2015 Alton EW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DD, Cunningham S, ... ... Wilson JM, et al. Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial. The Lancet. Respiratory Medicine. PMID 26149841 DOI: 10.1016/S2213-2600(15)00245-3  0.349
2015 Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Leyton CK, Leung HC, Kruse RL, Himes RW, Goss JA, Wilson JM, et al. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. Nature Communications. 6: 7339. PMID 26081744 DOI: 10.1038/Ncomms8339  0.386
2015 Calcedo R, Franco J, Qin Q, Richardson DW, Mason JB, Boyd S, Wilson JM. Preexisting Neutralizing Antibodies to Adeno-Associated Virus Capsids in Large Animals Other Than Monkeys May Confound In Vivo Gene Therapy Studies. Human Gene Therapy Methods. 26: 103-5. PMID 26067568 DOI: 10.1089/Hgtb.2015.082  0.427
2015 Hinderer C, Bell P, Louboutin JP, Zhu Y, Yu H, Lin G, Choa R, Gurda BL, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Tarantal AF, Casal ML, ... ... Wilson JM, et al. Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26022732 DOI: 10.1038/Mt.2015.99  0.474
2015 Ortved K, Wagner B, Calcedo R, Wilson J, Schaefer D, Nixon A. Humoral and cell-mediated immune response, and growth factor synthesis after direct intraarticular injection of rAAV2-IGF-I and rAAV5-IGF-I in the equine middle carpal joint. Human Gene Therapy. 26: 161-71. PMID 25705927 DOI: 10.1089/Hum.2014.050  0.377
2015 Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, ... ... Wilson JM, et al. Perspectives on best practices for gene therapy programs. Human Gene Therapy. 26: 127-33. PMID 25654329 DOI: 10.1089/Hum.2014.147  0.622
2015 Tomalka J, Azodi E, Narra HP, Patel K, O'Neill S, Cardwell C, Hall BA, Wilson JM, Hise AG. β-Defensin 1 plays a role in acute mucosal defense against Candida albicans. Journal of Immunology (Baltimore, Md. : 1950). 194: 1788-95. PMID 25595775 DOI: 10.4049/Jimmunol.1203239  0.301
2015 Giles AR, Calcedo R, Boyd S, Qin Q, Schneider M, Tretiakova A, Wilson JM. 646. Isolation and Evaluation of Novel Anti-AAV2 and AAV3B Antibody Clones from a Human Donor Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34255-1  0.342
2015 Ashley S, McMenamin D, Draper C, Somanathan S, Wilson JM. 525. CD8+ T Cell Tolerance To Epitopes Downstream of Non-Sense Mutations Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34134-X  0.388
2015 Wang L, Bell P, Morizono H, He Z, Pumbo E, White J, Batshaw ML, Wilson JM. 174. Liver Fibrosis in Aged OTC-KO Heterozygotes and Successful Correction by AAV8-Mediated Gene Therapy Molecular Therapy. 23: S69. DOI: 10.1016/S1525-0016(16)33779-0  0.353
2015 Wang Q, Lock M, Prongay A, Alvira MR, Petkov B, Wilson JM. 90. Identification of an Adeno-Associated Virus Binding Epitope for AVB Sepharose Affinity Resin Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33695-4  0.303
2015 Christopher DM, Billheimer J, Marchadier D, Susztak K, Remaley A, Wilson J, Rader DJ. 9. AAV-Mediated Gene Transfer as a Therapeutic Approach for Familial LCAT Deficiency Molecular Therapy. 23: S4. DOI: 10.1016/S1525-0016(16)33613-9  0.378
2015 Wilson JM, Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin J, Zhu Y, Choa R, Lin G, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME. Adeno-associated virus vector-mediated gene therapy can effectively treat CNS and cardiac lesions and induce immune tolerance to the therapeutic enzyme in large animal models of mucopolysaccharidosis type I Molecular Genetics and Metabolism. 114: S126-S127. DOI: 10.1016/J.Ymgme.2014.12.290  0.401
2015 Ponder K, Kobayashi H, Ohashi T, Izuka S, Bell P, Gurda B, Wilson J, Casal M, Haskins M. Intrathecal injection of lentiviral vector results in high expression in the brain of mucopolysaccharidosis VII dogs but the pattern of expression is different than for AAV9 or AAV-rh10 Molecular Genetics and Metabolism. 114. DOI: 10.1016/J.Ymgme.2014.12.213  0.324
2014 Hinderer C, Bell P, Vite CH, Louboutin JP, Grant R, Bote E, Yu H, Pukenas B, Hurst R, Wilson JM. Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna. Molecular Therapy. Methods & Clinical Development. 1: 14051. PMID 26052519 DOI: 10.1038/Mtm.2014.51  0.448
2014 Greig JA, Peng H, Ohlstein J, Medina-Jaszek CA, Ahonkhai O, Mentzinger A, Grant RL, Roy S, Chen SJ, Bell P, Tretiakova AP, Wilson JM. Intramuscular injection of AAV8 in mice and macaques is associated with substantial hepatic targeting and transgene expression. Plos One. 9: e112268. PMID 25393537 DOI: 10.1371/Journal.Pone.0112268  0.446
2014 Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM. Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I. Proceedings of the National Academy of Sciences of the United States of America. 111: 14894-9. PMID 25267637 DOI: 10.1073/Pnas.1413645111  0.389
2014 Adam VS, Crosariol M, Kumar S, Ge MQ, Czack SE, Roy S, Haczku A, Tretiakova A, Wilson JM, Limberis MP. Adeno-associated virus 9-mediated airway expression of antibody protects old and immunodeficient mice against influenza virus. Clinical and Vaccine Immunology : Cvi. 21: 1528-33. PMID 25209558 DOI: 10.1128/Cvi.00572-14  0.344
2014 Brennan TA, Wilson JM. The special case of gene therapy pricing. Nature Biotechnology. 32: 874-6. PMID 25203033 DOI: 10.1038/Nbt.3003  0.334
2014 Myint M, Limberis MP, Bell P, Somanathan S, Haczku A, Wilson JM, Diamond SL. In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection. Human Gene Therapy. 25: 966-76. PMID 25144316 DOI: 10.1089/Hum.2014.002  0.398
2014 Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM. Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis I. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2018-27. PMID 25027660 DOI: 10.1038/Mt.2014.135  0.413
2014 Somanathan S, Jacobs F, Wang Q, Hanlon AL, Wilson JM, Rader DJ. AAV vectors expressing LDLR gain-of-function variants demonstrate increased efficacy in mouse models of familial hypercholesterolemia. Circulation Research. 115: 591-9. PMID 25023731 DOI: 10.1161/Circresaha.115.304008  0.39
2014 Bell P, Vandenberghe LH, Wilson JM. Formation of newly synthesized adeno-associated virus capsids in the cell nucleus. Human Gene Therapy Methods. 25: 179-80. PMID 24933465 DOI: 10.1089/hgtb.2014.054  0.558
2014 Bukh I, Calcedo R, Roy S, Carnathan DG, Grant R, Qin Q, Boyd S, Ratcliffe SJ, Veeder CL, Bellamy SL, Betts MR, Wilson JM. Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector. Journal of Virology. 88: 8468-78. PMID 24829340 DOI: 10.1128/Jvi.03850-13  0.334
2014 Wilson JM. Genetic diseases, immunology, viruses, and gene therapy. Human Gene Therapy. 25: 257-61. PMID 24754432 DOI: 10.1089/Hum.2014.2511  0.36
2014 Tenney RM, Bell CL, Wilson JM. AAV8 capsid variable regions at the two-fold symmetry axis contribute to high liver transduction by mediating nuclear entry and capsid uncoating. Virology. 454: 227-36. PMID 24725949 DOI: 10.1016/J.Virol.2014.02.017  0.785
2014 Mikals K, Nam HJ, Van Vliet K, Vandenberghe LH, Mays LE, McKenna R, Wilson JM, Agbandje-McKenna M. The structure of AAVrh32.33, a novel gene delivery vector. Journal of Structural Biology. 186: 308-17. PMID 24704217 DOI: 10.1016/J.Jsb.2014.03.020  0.79
2014 Huang J, Li X, Coelho-dos-Reis JG, Wilson JM, Tsuji M. An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice. Plos One. 9: e88205. PMID 24516613 DOI: 10.1371/Journal.Pone.0088205  0.406
2014 Wilson JM. The first journal on human gene therapy celebrates its 25th anniversary. Human Gene Therapy. 25: 1-2. PMID 24444178 DOI: 10.1089/Hum.2013.2528  0.389
2014 Lock M, Alvira MR, Chen SJ, Wilson JM. Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR. Human Gene Therapy Methods. 25: 115-25. PMID 24328707 DOI: 10.1089/Hgtb.2013.131  0.303
2014 Mays LE, Wang L, Lin J, Bell P, Crawford A, Wherry EJ, Wilson JM. AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 28-41. PMID 23778424 DOI: 10.1038/Mt.2013.134  0.705
2014 Griesenbach U, Boyd A, Calcedo R, Cheng S, Cunningham S, Davies J, Dewar M, Gill, Doherty A, Higgins T, Hyde S, Manvell M, Meng C, Innes J, Limberis M, ... ... Wilson J, et al. P204 Immune Responses To Single And Repeated Administration Of Pgm169/gl67a: The Uk Cf Gene Therapy Consortium Clinical Trials Thorax. 69. DOI: 10.1136/Thoraxjnl-2014-206260.333  0.345
2014 Gurda B, Wang P, Bell P, Bagel J, Sikora T, O'Donnell P, Zhu Y, Ruane T, Calcedo R, Yu H, Casal M, Vite C, Ponder K, Wilson J, Haskins M. Gene therapy for mucopolysaccharidosis VII: evaluation of intrathecal rAAV vectors in the canine model Molecular Genetics and Metabolism. 111. DOI: 10.1016/J.Ymgme.2013.12.107  0.394
2013 Mueller C, Chulay JD, Trapnell BC, Humphries M, Carey B, Sandhaus RA, McElvaney NG, Messina L, Tang Q, Rouhani FN, Campbell-Thompson M, Fu AD, Yachnis A, Knop DR, Ye GJ, ... ... Wilson JM, et al. Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression. The Journal of Clinical Investigation. 123: 5310-8. PMID 24231351 DOI: 10.1172/Jci70314  0.406
2013 Calcedo R, Wilson JM. Humoral Immune Response to AAV. Frontiers in Immunology. 4: 341. PMID 24151496 DOI: 10.3389/Fimmu.2013.00341  0.442
2013 Limberis MP, Racine T, Kobasa D, Li Y, Gao GF, Kobinger G, Wilson JM. Vectored expression of the broadly neutralizing antibody FI6 in mouse airway provides partial protection against a new avian influenza A virus, H7N9. Clinical and Vaccine Immunology : Cvi. 20: 1836-7. PMID 24132603 DOI: 10.1128/Cvi.00545-13  0.468
2013 Faust SM, Bell P, Zhu Y, Sanmiguel J, Wilson JM. The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2227-35. PMID 24126962 DOI: 10.1038/Mt.2013.94  0.431
2013 Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM. Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia. Human Gene Therapy. Clinical Development. 24: 154-60. PMID 24070336 DOI: 10.1089/Humc.2013.082  0.76
2013 Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Büning H, Schwartz O, Knops E, Kaiser R, Seaman MS, ... Wilson JM, et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 16538-43. PMID 24043801 DOI: 10.1073/Pnas.1315295110  0.31
2013 Zhong L, Li S, Li M, Xie J, Zhang Y, Lee B, Batshaw ML, Wilson JM, Gao G. Vector sequences are not detected in tumor tissue from research subjects with ornithine transcarbamylase deficiency who previously received adenovirus gene transfer. Human Gene Therapy. 24: 814-9. PMID 24010702 DOI: 10.1089/Hum.2013.118  0.51
2013 Wilson JM. Bulls, bubbles, and biotech. Human Gene Therapy. 24: 715-6. PMID 23944718 DOI: 10.1089/Hum.2013.2509  0.327
2013 Chen SJ, Johnston J, Sandhu A, Bish LT, Hovhannisyan R, Jno-Charles O, Sweeney HL, Wilson JM. Enhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression. Human Gene Therapy Methods. 24: 270-8. PMID 23895325 DOI: 10.1089/Hgtb.2012.129  0.462
2013 Bryant LM, Christopher DM, Giles AR, Hinderer C, Rodriguez JL, Smith JB, Traxler EA, Tycko J, Wojno AP, Wilson JM. Lessons learned from the clinical development and market authorization of Glybera. Human Gene Therapy. Clinical Development. 24: 55-64. PMID 23808604 DOI: 10.1089/Humc.2013.087  0.328
2013 Calcedo R, Griesenbach U, Dorgan DJ, Soussi S, Boyd AC, Davies JC, Higgins TE, Hyde SC, Gill DR, Innes JA, Porteous DJ, Alton EW, Wilson JM, Limberis MP. Self-reactive CFTR T cells in humans: implications for gene therapy. Human Gene Therapy. Clinical Development. 24: 108-15. PMID 23790242 DOI: 10.1089/Humc.2012.249  0.354
2013 Faust SM, Bell P, Cutler BJ, Ashley SN, Zhu Y, Rabinowitz JE, Wilson JM. CpG-depleted adeno-associated virus vectors evade immune detection. The Journal of Clinical Investigation. 123: 2994-3001. PMID 23778142 DOI: 10.1172/Jci68205  0.43
2013 Mays LE, Wang L, Tenney R, Bell P, Nam HJ, Lin J, Gurda B, Van Vliet K, Mikals K, Agbandje-McKenna M, Wilson JM. Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33. Journal of Virology. 87: 9473-85. PMID 23720715 DOI: 10.1128/Jvi.00596-13  0.785
2013 Limberis MP, Adam VS, Wong G, Gren J, Kobasa D, Ross TM, Kobinger GP, Tretiakova A, Wilson JM. Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza. Science Translational Medicine. 5: 187ra72. PMID 23720583 DOI: 10.1126/Scitranslmed.3006299  0.347
2013 McDonald CL, Benson J, Cornetta K, Diggins M, Johnston JC, Sepelak S, Wang G, Wilson JM, Wright JF, Skarlatos SI. Advancing translational research through the NHLBI Gene Therapy Resource Program (GTRP). Human Gene Therapy. Clinical Development. 24: 5-10. PMID 23692378 DOI: 10.1089/Humc.2013.036  0.314
2013 Mason JB, Gurda BL, Engiles JB, Hankenson KD, Wilson JM, Richardson DW. Multiple recombinant adeno-associated viral vector serotypes display persistent in vivo gene expression in vector-transduced rat stifle joints. Human Gene Therapy Methods. 24: 185-94. PMID 23659250 DOI: 10.1089/Hgtb.2012.199  0.386
2013 Zhong L, Malani N, Li M, Brady T, Xie J, Bell P, Li S, Jones H, Wilson JM, Flotte TR, Bushman FD, Gao G. Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction. Human Gene Therapy. 24: 520-5. PMID 23621841 DOI: 10.1089/Hum.2012.112  0.505
2013 O'Reilly M, Kohn DB, Bartlett J, Benson J, Brooks PJ, Byrne BJ, Camozzi C, Cornetta K, Crystal RG, Fong Y, Gargiulo L, Gopal-Srivastava R, High KA, Jacobson SG, Jambou RC, ... ... Wilson JM, et al. Gene therapy for rare diseases: summary of a National Institutes of Health workshop, September 13, 2012. Human Gene Therapy. 24: 355-62. PMID 23517518 DOI: 10.1089/Hum.2013.064  0.344
2013 Vandenberghe LH, Bell P, Maguire AM, Xiao R, Hopkins TB, Grant R, Bennett J, Wilson JM. AAV9 targets cone photoreceptors in the nonhuman primate retina. Plos One. 8: e53463. PMID 23382846 DOI: 10.1371/Journal.Pone.0053463  0.687
2013 Raper SE, Wilson JM, Nunes FA. Flushing out antibodies to make AAV gene therapy available to more patients. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 269-71. PMID 23369966 DOI: 10.1038/Mt.2013.5  0.462
2013 Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, ... ... Wilson JM, et al. Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 266-8. PMID 23369965 DOI: 10.1038/Mt.2013.4  0.806
2013 Ferla R, O'Malley T, Calcedo R, O'Donnell P, Wang P, Cotugno G, Claudiani P, Wilson JM, Haskins M, Auricchio A. Gene therapy for mucopolysaccharidosis type VI is effective in cats without pre-existing immunity to AAV8. Human Gene Therapy. 24: 163-9. PMID 23194248 DOI: 10.1089/Hum.2012.179  0.623
2013 Kassim SH, Li H, Bell P, Somanathan S, Lagor W, Jacobs F, Billheimer J, Wilson JM, Rader DJ. Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia. Human Gene Therapy. 24: 19-26. PMID 22985273 DOI: 10.1089/Hum.2012.108  0.751
2013 Vandenberghe LH, Bell P, Maguire AM, Xiao R, Hopkins TB, Grant R, Bennett J, Wilson JM. Correction: AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina Plos One. 8. DOI: 10.1371/Annotation/64B90996-4634-4C63-B737-634397B0B445  0.627
2013 Wilson JM. Is this gene therapy's breakout moment?: Flurry of activity in sector driven by investment from venture capital community Genetic Engineering and Biotechnology News. 33: 62. DOI: 10.1089/Gen.33.7.25  0.31
2013 Wilson JM. AAV Vectors for Infectious Diseases Genetic Engineering & Biotechnology News. 33: 50-51. DOI: 10.1089/Gen.33.15.21  0.318
2013 Wilson JM. Glybera's story mirrors that of gene therapy Genetic Engineering and Biotechnology News. 33: 40. DOI: 10.1089/Gen.33.01.25  0.346
2013 Mason JB, Gurda BL, Engiles JB, Wilson JM, Richardson DW. In vivo gene therapy of the equine distal extremity with recombinant adeno-associated viral vectors for the treatment of laminitis Journal of Equine Veterinary Science. 33: 867. DOI: 10.1016/J.Jevs.2013.08.048  0.43
2012 Wilson JM. Moving to the clinic with gene therapy through our new journal expansion, human gene therapy clinical development. Human Gene Therapy. 23: 1029-30. PMID 23030253 DOI: 10.1089/Hum.2012.2520  0.364
2012 Keswani SG, Balaji S, Le L, Leung A, Katz AB, Lim FY, Habli M, Jones HN, Wilson JM, Crombleholme TM. Pseudotyped AAV vector-mediated gene transfer in a human fetal trachea xenograft model: implications for in utero gene therapy for cystic fibrosis. Plos One. 7: e43633. PMID 22937069 DOI: 10.1371/Journal.Pone.0043633  0.464
2012 Mason JB, Vandenberghe LH, Xiao R, Wilson JM, Richardson DW. Influence of serotype, cell type, tissue composition, and time after inoculation on gene expression in recombinant adeno-associated viral vector-transduced equine joint tissues. American Journal of Veterinary Research. 73: 1178-85. PMID 22849678 DOI: 10.2460/Ajvr.73.8.1178  0.627
2012 Keswani SG, Balaji S, Le L, Leung A, Lim FY, Habli M, Jones HN, Wilson JM, Crombleholme TM. Pseudotyped adeno-associated viral vector tropism and transduction efficiencies in murine wound healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 20: 592-600. PMID 22713157 DOI: 10.1111/J.1524-475X.2012.00810.X  0.46
2012 Bell CL, Gurda BL, Van Vliet K, Agbandje-McKenna M, Wilson JM. Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid. Journal of Virology. 86: 7326-33. PMID 22514350 DOI: 10.1128/Jvi.00448-12  0.65
2012 Lock M, Alvira MR, Wilson JM. Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography. Human Gene Therapy Methods. 23: 56-64. PMID 22428980 DOI: 10.1089/Hgtb.2011.217  0.388
2012 Wilson JM. It's time for gene therapy to get disruptive! Human Gene Therapy. 23: 1-3. PMID 22247960 DOI: 10.1089/Hum.2011.2530  0.339
2012 Bish LT, Sleeper MM, Forbes SC, Wang B, Reynolds C, Singletary GE, Trafny D, Morine KJ, Sanmiguel J, Cecchini S, Virag T, Vulin A, Beley C, Bogan J, Wilson JM, et al. Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 580-9. PMID 22146342 DOI: 10.1038/Mt.2011.264  0.311
2012 Wang L, Morizono H, Lin J, Bell P, Jones D, McMenamin D, Yu H, Batshaw ML, Wilson JM. Preclinical evaluation of a clinical candidate AAV8 vector for ornithine transcarbamylase (OTC) deficiency reveals functional enzyme from each persisting vector genome. Molecular Genetics and Metabolism. 105: 203-11. PMID 22133298 DOI: 10.1016/J.Ymgme.2011.10.020  0.46
2012 Wang L, Wang H, Bell P, McMenamin D, Wilson JM. Hepatic gene transfer in neonatal mice by adeno-associated virus serotype 8 vector. Human Gene Therapy. 23: 533-9. PMID 22098408 DOI: 10.1089/Hum.2011.183  0.448
2012 Wang L, Wang H, Morizono H, Bell P, Jones D, Lin J, McMenamin D, Yu H, Batshaw ML, Wilson JM. Sustained correction of OTC deficiency in spf( ash) mice using optimized self-complementary AAV2/8 vectors. Gene Therapy. 19: 404-10. PMID 21850052 DOI: 10.1038/Gt.2011.111  0.456
2012 Kozarsky KF, Wilson JM. Gene therapy of hypercholesterolemic disorders. Trends in Cardiovascular Medicine. 5: 205-9. PMID 21232261 DOI: 10.1016/1050-1738(95)00078-N  0.381
2012 Bukh I, Calcedo R, Roy S, Carnathan D, Grant R, Ratcliffe S, Wilson J, Betts M. Increased mucosal CD4+ T-cell activation following vaccination with an adenoviral vector in rhesus macaques Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P267  0.354
2012 Haskins M, Sleeper M, Aguirre G, Walkley SU, Knox V, Vite C, Steet R, Gurda B, Wilson J, Auricchio A, Smith L, Simonaro L, Ponder K. Large Animal Models of Lysosomal Storage Diseases: Lessons on the Limits of Gene/Enzyme Therapy Molecular Genetics and Metabolism. 105: S33-S34. DOI: 10.1016/J.Ymgme.2011.11.071  0.562
2012 Gurda B, Bell P, Zhu Y, Wang P, O'Donnell P, Sanmiguel J, Vandenberghe L, Haskins M, Wilson J. Liver-Directed Gene Therapy for Mucopolysaccharidosis Type I (MPS I) Molecular Genetics and Metabolism. 105: S32. DOI: 10.1016/J.Ymgme.2011.11.067  0.622
2011 Wang L, Louboutin JP, Bell P, Greig JA, Li Y, Wu D, Wilson JM. Muscle-directed gene therapy for hemophilia B with more efficient and less immunogenic AAV vectors. Journal of Thrombosis and Haemostasis : Jth. 9: 2009-19. PMID 21883883 DOI: 10.1111/J.1538-7836.2011.04491.X  0.473
2011 Wang L, Bell P, Lin J, Calcedo R, Tarantal AF, Wilson JM. AAV8-mediated hepatic gene transfer in infant rhesus monkeys (Macaca mulatta). Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2012-20. PMID 21811248 DOI: 10.1038/Mt.2011.151  0.386
2011 Bell P, Wang L, Gao G, Haskins ME, Tarantal AF, McCarter RJ, Zhu Y, Yu H, Wilson JM. Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates. Molecular Genetics and Metabolism. 104: 395-403. PMID 21778099 DOI: 10.1016/J.Ymgme.2011.06.002  0.551
2011 Calcedo R, Morizono H, Wang L, McCarter R, He J, Jones D, Batshaw ML, Wilson JM. Adeno-associated virus antibody profiles in newborns, children, and adolescents. Clinical and Vaccine Immunology : Cvi. 18: 1586-8. PMID 21775517 DOI: 10.1128/Cvi.05107-11  0.359
2011 Aleman TS, Cideciyan AV, Aguirre GK, Huang WC, Mullins CL, Roman AJ, Sumaroka A, Olivares MB, Tsai FF, Schwartz SB, Vandenberghe LH, Limberis MP, Stone EM, Bell P, Wilson JM, et al. Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model. Investigative Ophthalmology & Visual Science. 52: 6898-910. PMID 21757580 DOI: 10.1167/Iovs.11-7701  0.584
2011 Vandenberghe LH, Bell P, Maguire AM, Cearley CN, Xiao R, Calcedo R, Wang L, Castle MJ, Maguire AC, Grant R, Wolfe JH, Wilson JM, Bennett J. Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey. Science Translational Medicine. 3: 88ra54. PMID 21697530 DOI: 10.1126/Scitranslmed.3002103  0.726
2011 Breous E, Somanathan S, Bell P, Wilson JM. Inflammation promotes the loss of adeno-associated virus-mediated transgene expression in mouse liver. Gastroenterology. 141: 348-57, 357.e1-3. PMID 21640112 DOI: 10.1053/J.Gastro.2011.04.002  0.412
2011 Kassim SH, Vandenberghe LH, Hovhannisyan R, Wilson JM, Rader DJ. Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques. Physiological Genomics. 43: 911-6. PMID 21628398 DOI: 10.1152/Physiolgenomics.00006.2011  0.786
2011 Flotte TR, Trapnell BC, Humphries M, Carey B, Calcedo R, Rouhani F, Campbell-Thompson M, Yachnis AT, Sandhaus RA, McElvaney NG, Mueller C, Messina LM, Wilson JM, Brantly M, Knop DR, et al. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results. Human Gene Therapy. 22: 1239-47. PMID 21609134 DOI: 10.1089/Hum.2011.053  0.43
2011 Bell CL, Vandenberghe LH, Bell P, Limberis MP, Gao GP, Van Vliet K, Agbandje-McKenna M, Wilson JM. The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice. The Journal of Clinical Investigation. 121: 2427-35. PMID 21576824 DOI: 10.1172/Jci57367  0.786
2011 Roy S, Clawson DS, Adam VS, Medina A, Wilson JM. Construction of gene transfer vectors based on simian adenovirus 7. The Journal of General Virology. 92: 1749-53. PMID 21562118 DOI: 10.1099/Vir.0.032300-0  0.414
2011 Bish LT, Sleeper MM, Reynolds C, Gazzara J, Withnall E, Singletary GE, Buchlis G, Hui D, High KA, Gao G, Wilson JM, Sweeney HL. Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines. Human Gene Therapy. 22: 969-77. PMID 21542669 DOI: 10.1089/Hum.2011.035  0.504
2011 Wang L, Calcedo R, Bell P, Lin J, Grant RL, Siegel DL, Wilson JM. Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors. Human Gene Therapy. 22: 1389-401. PMID 21476868 DOI: 10.1089/Hum.2011.031  0.482
2011 Wilson JM. The technology of gene therapy. Human Gene Therapy. 22: 117. PMID 21329434 DOI: 10.1089/Hum.2011.1092  0.328
2011 Van der Perren A, Toelen J, Carlon M, Van den Haute C, Coun F, Heeman B, Reumers V, Vandenberghe LH, Wilson JM, Debyser Z, Baekelandt V. Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9. Gene Therapy. 18: 517-27. PMID 21326331 DOI: 10.1038/Gt.2010.179  0.722
2011 Roy S, Medina-Jaszek A, Wilson MJ, Sandhu A, Calcedo R, Lin J, Wilson JM. Creation of a panel of vectors based on ape adenovirus isolates. The Journal of Gene Medicine. 13: 17-25. PMID 21259405 DOI: 10.1002/Jgm.1530  0.365
2011 Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM. Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs. Human Gene Therapy. 22: 985-97. PMID 21204705 DOI: 10.1089/Hum.2010.194  0.714
2011 Mays LE, Wilson JM. The complex and evolving story of T cell activation to AAV vector-encoded transgene products. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 16-27. PMID 21119617 DOI: 10.1038/Mt.2010.250  0.75
2011 Wilson JM. The birth of human gene therapy methods Human Gene Therapy. 22: 1039-1040. DOI: 10.1089/Hum.2011.2516  0.362
2010 Wilson JM. In the Beginning: Reflections on the Genesis of Molecular Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 9-10. PMID 28178553 DOI: 10.1038/Mt.2009.284  0.308
2010 Kassim SH, Wilson JM, Rader DJ. Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies. Clinical Lipidology. 5: 793-809. PMID 22505953 DOI: 10.2217/Clp.10.73  0.726
2010 Wilson JM. Autoimmunity, recessive diseases, and gene replacement therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2045-7. PMID 21119692 DOI: 10.1038/Mt.2010.253  0.42
2010 Kassim SH, Li H, Vandenberghe LH, Hinderer C, Bell P, Marchadier D, Wilson A, Cromley D, Redon V, Yu H, Wilson JM, Rader DJ. Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis. Plos One. 5: e13424. PMID 20976059 DOI: 10.1371/Journal.Pone.0013424  0.796
2010 Zhang L, Limberis MP, Thompson C, Antunes MB, Luongo C, Wilson JM, Collins PL, Pickles RJ. α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors. Human Gene Therapy. 21: 1657-64. PMID 20735256 DOI: 10.1089/Hum.2010.065  0.465
2010 Goodman AL, Epp C, Moss D, Holder AA, Wilson JM, Gao GP, Long CA, Remarque EJ, Thomas AW, Ammendola V, Colloca S, Dicks MD, Biswas S, Seibel D, van Duivenvoorde LM, et al. New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1. Infection and Immunity. 78: 4601-12. PMID 20713623 DOI: 10.1128/Iai.00315-10  0.49
2010 Carlon M, Toelen J, Van der Perren A, Vandenberghe LH, Reumers V, Sbragia L, Gijsbers R, Baekelandt V, Himmelreich U, Wilson JM, Deprest J, Debyser Z. Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 2130-8. PMID 20664525 DOI: 10.1038/Mt.2010.153  0.724
2010 Vandenberghe LH, Xiao R, Lock M, Lin J, Korn M, Wilson JM. Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing. Human Gene Therapy. 21: 1251-7. PMID 20649475 DOI: 10.1089/Hum.2010.107  0.659
2010 Lin J, Somanathan S, Roy S, Calcedo R, Wilson JM. Lung homing CTLs and their proliferation ability are important correlates of vaccine protection against influenza. Vaccine. 28: 5669-75. PMID 20600493 DOI: 10.1016/J.Vaccine.2010.06.053  0.367
2010 Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM. Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale. Human Gene Therapy. 21: 1259-71. PMID 20497038 DOI: 10.1089/Hum.2010.055  0.717
2010 Somanathan S, Breous E, Bell P, Wilson JM. AAV vectors avoid inflammatory signals necessary to render transduced hepatocyte targets for destructive T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 977-82. PMID 20234342 DOI: 10.1038/Mt.2010.40  0.401
2010 Sun X, Lu Y, Bish LT, Calcedo R, Wilson JM, Gao G. Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate models. Human Gene Therapy. 21: 750-61. PMID 20113166 DOI: 10.1089/Hum.2009.214  0.531
2010 Breous E, Somanathan S, Wilson JM. BALB/c mice show impaired hepatic tolerogenic response following AAV gene transfer to the liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 766-74. PMID 20068550 DOI: 10.1038/Mt.2009.301  0.395
2010 Wang L, Calcedo R, Wang H, Bell P, Grant R, Vandenberghe LH, Sanmiguel J, Morizono H, Batshaw ML, Wilson JM. The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 126-34. PMID 19888196 DOI: 10.1038/Mt.2009.245  0.692
2010 Wang L, Wang H, Bell P, McCarter RJ, He J, Calcedo R, Vandenberghe LH, Morizono H, Batshaw ML, Wilson JM. Systematic evaluation of AAV vectors for liver directed gene transfer in murine models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 118-25. PMID 19861950 DOI: 10.1038/Mt.2009.246  0.681
2010 Flotte TR, Fischer AC, Goetzmann J, Mueller C, Cebotaru L, Yan Z, Wang L, Wilson JM, Guggino WB, Engelhardt JF. Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 594-600. PMID 19826405 DOI: 10.1038/Mt.2009.230  0.44
2010 Limberis MP, Bell CL, Heath J, Wilson JM. Activation of transgene-specific T cells following lentivirus-mediated gene delivery to mouse lung. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 143-50. PMID 19724265 DOI: 10.1038/Mt.2009.190  0.681
2009 Wilson JM. Progress in the commercial-scale production of adeno-associated viral vectors Human Gene Therapy. 20: 695. PMID 19848589 DOI: 10.1089/Hum.2009.1615  0.308
2009 Lin J, Calcedo R, Vandenberghe LH, Bell P, Somanathan S, Wilson JM. A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque. Journal of Virology. 83: 12738-50. PMID 19812149 DOI: 10.1128/Jvi.01441-09  0.661
2009 Mays LE, Wilson JM. Identification of the murine AAVrh32.33 capsid-specific CD8+ T cell epitopes. The Journal of Gene Medicine. 11: 1095-102. PMID 19777488 DOI: 10.1002/Jgm.1402  0.736
2009 Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A, Johnston J, Debyser Z, Agbandje-McKenna M, Wilson JM. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. Gene Therapy. 16: 1416-28. PMID 19727141 DOI: 10.1038/Gt.2009.101  0.759
2009 Brantly ML, Chulay JD, Wang L, Mueller C, Humphries M, Spencer LT, Rouhani F, Conlon TJ, Calcedo R, Betts MR, Spencer C, Byrne BJ, Wilson JM, Flotte TR. Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 16363-8. PMID 19706466 DOI: 10.1073/Pnas.0904514106  0.421
2009 Fein DE, Limberis MP, Maloney SF, Heath JM, Wilson JM, Diamond SL. Cationic lipid formulations alter the in vivo tropism of AAV2/9 vector in lung. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2078-87. PMID 19638960 DOI: 10.1038/Mt.2009.173  0.407
2009 Zhang H, Xie J, Xie Q, Wilson JM, Gao G. Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production. Human Gene Therapy. 20: 922-9. PMID 19618999 DOI: 10.1089/Hum.2009.125  0.53
2009 Roy S, Vandenberghe LH, Kryazhimskiy S, Grant R, Calcedo R, Yuan X, Keough M, Sandhu A, Wang Q, Medina-Jaszek CA, Plotkin JB, Wilson JM. Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates. Plos Pathogens. 5: e1000503. PMID 19578438 DOI: 10.1371/Journal.Ppat.1000503  0.622
2009 Breous E, Somanathan S, Vandenberghe LH, Wilson JM. Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver. Hepatology (Baltimore, Md.). 50: 612-21. PMID 19575456 DOI: 10.1002/Hep.23043  0.613
2009 Gao G, Wang Q, Calcedo R, Mays L, Bell P, Wang L, Vandenberghe LH, Grant R, Sanmiguel J, Furth EE, Wilson JM. Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses. Human Gene Therapy. 20: 930-42. PMID 19441963 DOI: 10.1089/Hum.2009.060  0.814
2009 Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM. Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins. Journal of Immunology (Baltimore, Md. : 1950). 182: 6051-60. PMID 19414756 DOI: 10.4049/Jimmunol.0803965  0.769
2009 Pichla-Gollon SL, Lin SW, Hensley SE, Lasaro MO, Herkenhoff-Haut L, Drinker M, Tatsis N, Gao GP, Wilson JM, Ertl HC, Bergelson JM. Effect of preexisting immunity on an adenovirus vaccine vector: in vitro neutralization assays fail to predict inhibition by antiviral antibody in vivo. Journal of Virology. 83: 5567-73. PMID 19279092 DOI: 10.1128/Jvi.00405-09  0.533
2009 Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG. Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing. Human Gene Therapy. 20: 267-81. PMID 19257851 DOI: 10.1089/Hum.2008.173  0.608
2009 Wilson JM. Lessons learned from the gene therapy trial for ornithine transcarbamylase deficiency. Molecular Genetics and Metabolism. 96: 151-7. PMID 19211285 DOI: 10.1016/J.Ymgme.2008.12.016  0.352
2009 Calcedo R, Vandenberghe LH, Gao G, Lin J, Wilson JM. Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses. The Journal of Infectious Diseases. 199: 381-90. PMID 19133809 DOI: 10.1086/595830  0.679
2009 Limberis MP, Bell CL, Wilson JM. Identification of the murine firefly luciferase-specific CD8 T-cell epitopes. Gene Therapy. 16: 441-7. PMID 19129859 DOI: 10.1038/Gt.2008.177  0.653
2009 Calcedo R, Vandenberghe LH, Roy S, Somanathan S, Wang L, Wilson JM. Host immune responses to chronic adenovirus infections in human and nonhuman primates. Journal of Virology. 83: 2623-31. PMID 19116257 DOI: 10.1128/Jvi.02160-08  0.645
2009 Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM. Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 294-301. PMID 19066597 DOI: 10.1038/Mt.2008.261  0.659
2009 Vandenberghe LH, Wilson JM, Gao G. Tailoring the AAV vector capsid for gene therapy. Gene Therapy. 16: 311-9. PMID 19052631 DOI: 10.1038/Gt.2008.170  0.724
2009 Song Y, Lou H, Boyer J, Limberis M, Vandenberghe L, Hackett N, Leopold P, Wilson J, Crystal R. Functional CFTR Expression in Cystic Fibrosis Airway Epithelial Cells by AAV6.2-mediated Segmental Trans-splicing Human Gene Therapy. 90205172040003. DOI: 10.1089/Hgt.2008.173  0.577
2009 Wilson JM, Wivel NA. CHAPTER 53 – Gene Therapy Genomic and Personalized Medicinevolumes I & Ii. 610-619. DOI: 10.1016/B978-0-12-369420-1.00053-6  0.348
2008 Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Lee Sweeney H. Percutaneous Transendocardial Delivery of Self-complementary Adeno-associated Virus 6 Achieves Global Cardiac Gene Transfer in Canines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1953-1959. PMID 28189009 DOI: 10.1038/Mt.2008.202  0.545
2008 Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL. Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1953-9. PMID 18813281 DOI: 10.1038/mt.2008.202  0.479
2008 Cideciyan AV, Aleman TS, Boye SL, Schwartz SB, Kaushal S, Roman AJ, Pang JJ, Sumaroka A, Windsor EA, Wilson JM, Flotte TR, Fishman GA, Heon E, Stone EM, Byrne BJ, et al. Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics. Proceedings of the National Academy of Sciences of the United States of America. 105: 15112-7. PMID 18809924 DOI: 10.1073/Pnas.0807027105  0.364
2008 Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL. Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Human Gene Therapy. 19: 1359-68. PMID 18795839 DOI: 10.1089/Hum.2008.123  0.502
2008 Gao G, Wang Q, Dai Z, Calcedo R, Sun X, Li G, Wilson JM. Adenovirus-based vaccines generate cytotoxic T lymphocytes to epitopes of NS1 from dengue virus that are present in all major serotypes. Human Gene Therapy. 19: 927-36. PMID 18788905 DOI: 10.1089/Hum.2008.011  0.489
2008 Cearley CN, Vandenberghe LH, Parente MK, Carnish ER, Wilson JM, Wolfe JH. Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1710-8. PMID 18714307 DOI: 10.1038/Mt.2008.166  0.651
2008 Lin J, Calcedo R, Vandenberghe LH, Figueredo JM, Wilson JM. Impact of preexisting vector immunity on the efficacy of adeno-associated virus-based HIV-1 Gag vaccines. Human Gene Therapy. 19: 663-9. PMID 18549307 DOI: 10.1089/Hum.2008.033  0.64
2008 Wilson JM, Gansbacher B, Berns KI, Bosch F, Kay MA, Naldini L, Wei YQ. Good news on the clinical gene transfer front. Human Gene Therapy. 19: 429-30. PMID 18507511 DOI: 10.1089/Hum.2008.0519  0.327
2008 Wilson JM. Adverse events in gene transfer trials and an agenda for the new year Human Gene Therapy. 19: 1-2. PMID 18370863 DOI: 10.1089/Hum.2008.0104  0.301
2008 Lebherz C, Maguire A, Tang W, Bennett J, Wilson JM. Novel AAV serotypes for improved ocular gene transfer. The Journal of Gene Medicine. 10: 375-82. PMID 18278824 DOI: 10.1002/Jgm.1126  0.608
2008 Sridhar S, Reyes-Sandoval A, Draper SJ, Moore AC, Gilbert SC, Gao GP, Wilson JM, Hill AV. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. Journal of Virology. 82: 3822-33. PMID 18256155 DOI: 10.1128/Jvi.02568-07  0.559
2008 Royo NC, Vandenberghe LH, Ma JY, Hauspurg A, Yu L, Maronski M, Johnston J, Dichter MA, Wilson JM, Watson DJ. Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicity. Brain Research. 1190: 15-22. PMID 18054899 DOI: 10.1016/J.Brainres.2007.11.015  0.61
2008 Patel A, Zhang Y, Croyle M, Tran K, Gray M, Strong J, Feldmann H, Wilson JM, Kobinger GP. Mucosal delivery of adenovirus-based vaccine protects against Ebola virus infection in mice. The Journal of Infectious Diseases. S413-20. PMID 17940978 DOI: 10.1086/520603  0.319
2008 Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney L. AAV9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat Human Gene Therapy. 81015093227032. DOI: 10.1089/Hgt.2008.123  0.502
2007 Limberis M, Bell P, Wilson JM. Detection of reporter gene expression in murine airways Methods of Molecular Biology. 411: 25-34. PMID 18287636 DOI: 10.1007/978-1-59745-549-7_3  0.333
2007 Alton E, Ferrari S, Griesenbach U, Aiuti A, Bachoud-Lévi AC, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, ... ... Wilson JM, et al. Progress and prospects: gene therapy clinical trials (part 2). Gene Therapy. 14: 1555-63. PMID 17984995 DOI: 10.1038/sj.gt.3303033  0.388
2007 Vandenberghe LH, Wilson JM. AAV as an immunogen. Current Gene Therapy. 7: 325-33. PMID 17979679 DOI: 10.2174/156652307782151416  0.686
2007 Zhang Z, Reenstra W, Weiner DJ, Louboutin JP, Wilson JM. The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells. Infection and Immunity. 75: 5985-92. PMID 17908812 DOI: 10.1128/Iai.00678-07  0.301
2007 Price AR, Limberis MP, Wilson JM, Diamond SL. Pulmonary delivery of adenovirus vector formulated with dexamethasone-spermine facilitates homologous vector re-administration. Gene Therapy. 14: 1594-604. PMID 17898795 DOI: 10.1038/Sj.Gt.3303031  0.376
2007 Roy S, Kobinger GP, Lin J, Figueredo J, Calcedo R, Kobasa D, Wilson JM. Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein. Vaccine. 25: 6845-51. PMID 17728024 DOI: 10.1016/J.Vaccine.2007.07.035  0.317
2007 Lin J, Zhi Y, Mays L, Wilson JM. Vaccines based on novel adeno-associated virus vectors elicit aberrant CD8+ T-cell responses in mice. Journal of Virology. 81: 11840-9. PMID 17715240 DOI: 10.1128/Jvi.01253-07  0.714
2007 Allocca M, Mussolino C, Garcia-Hoyos M, Sanges D, Iodice C, Petrillo M, Vandenberghe LH, Wilson JM, Marigo V, Surace EM, Auricchio A. Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors. Journal of Virology. 81: 11372-80. PMID 17699581 DOI: 10.1128/Jvi.01327-07  0.722
2007 Limberis MP, Figueredo J, Calcedo R, Wilson JM. Activation of CFTR-specific T Cells in cystic fibrosis mice following gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1694-700. PMID 17579582 DOI: 10.1038/Sj.Mt.6300210  0.425
2007 Kobinger GP, Figueredo JM, Rowe T, Zhi Y, Gao G, Sanmiguel JC, Bell P, Wivel NA, Zitzow LA, Flieder DB, Hogan RJ, Wilson JM. Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques. Vaccine. 25: 5220-31. PMID 17559989 DOI: 10.1016/J.Vaccine.2007.04.065  0.479
2007 Kobinger GP, Limberis MP, Somanathan S, Schumer G, Bell P, Wilson JM. Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells. Human Gene Therapy. 18: 413-22. PMID 17518614 DOI: 10.1089/Hum.2006.194  0.368
2007 Bell P, Vandenberghe LH, Wu D, Johnston J, Limberis M, Wilson JM. A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 931-9. PMID 17510373 DOI: 10.1369/Jhc.7A7180.2007  0.647
2007 Lebherz C, Sanmiguel J, Wilson JM, Rader DJ. Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent. Cardiovascular Diabetology. 6: 15. PMID 17475009 DOI: 10.1186/1475-2840-6-15  0.384
2007 Taymans JM, Vandenberghe LH, Haute CV, Thiry I, Deroose CM, Mortelmans L, Wilson JM, Debyser Z, Baekelandt V. Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Human Gene Therapy. 18: 195-206. PMID 17343566 DOI: 10.1089/Hum.2006.178  0.719
2007 Wang L, Figueredo J, Calcedo R, Lin J, Wilson JM. Cross-presentation of adeno-associated virus serotype 2 capsids activates cytotoxic T cells but does not render hepatocytes effective cytolytic targets. Human Gene Therapy. 18: 185-94. PMID 17324107 DOI: 10.1089/Hum.2007.001  0.392
2007 Hachiya A, Sriwiriyanont P, Patel A, Saito N, Ohuchi A, Kitahara T, Takema Y, Tsuboi R, Boissy RE, Visscher MO, Wilson JM, James WM, Kobinger GP. Gene transfer in human skin with different pseudotyped HIV-based vectors. Gene Therapy. 14: 648-56. PMID 17268532 DOI: 10.1038/Sj.Gt.3302915  0.383
2007 Tatsis N, Blejer A, Lasaro MO, Hensley SE, Cun A, Tesema L, Li Y, Gao GP, Xiang ZQ, Zhou D, Wilson JM, Ertl HC. A CD46-binding chimpanzee adenovirus vector as a vaccine carrier. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 608-17. PMID 17228314 DOI: 10.1038/Sj.Mt.6300078  0.542
2007 Figueredo J, Limberis MP, Wilson JM. Prediction of cellular immune responses against CFTR in patients with cystic fibrosis after gene therapy. American Journal of Respiratory Cell and Molecular Biology. 36: 529-33. PMID 17218617 DOI: 10.1165/Rcmb.2006-0313Cb  0.36
2007 Roy S, Clawson DS, Lavrukhin O, Sandhu A, Miller J, Wilson JM. Rescue of chimeric adenoviral vectors to expand the serotype repertoire. Journal of Virological Methods. 141: 14-21. PMID 17197043 DOI: 10.1016/J.Jviromet.2006.11.022  0.409
2007 Sondhi D, Hackett NR, Peterson DA, Stratton J, Baad M, Travis KM, Wilson JM, Crystal RG. Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 481-91. PMID 17180118 DOI: 10.1038/Sj.Mt.6300049  0.417
2007 Pichla-Gollon SL, Drinker M, Zhou X, Xue F, Rux JJ, Gao GP, Wilson JM, Ertl HC, Burnett RM, Bergelson JM. Structure-based identification of a major neutralizing site in an adenovirus hexon. Journal of Virology. 81: 1680-9. PMID 17108028 DOI: 10.1128/Jvi.02023-06  0.467
2007 Vandendriessche T, Thorrez L, Acosta-Sanchez A, Petrus I, Wang L, Ma L, Waele LD, Iwasaki Y, Gillijns V, Wilson JM, Collen D, Chuah MKL. Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy. Journal of Thrombosis and Haemostasis. 5: 16-24. PMID 17002653 DOI: 10.1111/J.1538-7836.2006.02220.X  0.48
2006 Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates". Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 150. PMID 28192691 DOI: 10.1016/J.Ymthe.2006.04.002  0.536
2006 Wilson JM. Regulation of gene therapy in China Human Gene Therapy. 17: 969. PMID 17032154 DOI: 10.1089/Hum.2006.17.969  0.349
2006 Limberis MP, Wilson JM. Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered. Proceedings of the National Academy of Sciences of the United States of America. 103: 12993-12998. PMID 16938846 DOI: 10.1073/Pnas.0601433103  0.444
2006 Roy S, Zhi Y, Kobinger GP, Figueredo J, Calcedo R, Miller JR, Feldmann H, Wilson JM. Generation of an adenoviral vaccine vector based on simian adenovirus 21. The Journal of General Virology. 87: 2477-85. PMID 16894185 DOI: 10.1099/Vir.0.81989-0  0.388
2006 Vandenberghe LH, Wang L, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, Wilson JM. Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid. Nature Medicine. 12: 967-71. PMID 16845388 DOI: 10.1038/Nm1445  0.714
2006 Kelkar S, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL. A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes. Journal of Virology. 80: 7781-5. PMID 16840360 DOI: 10.1128/Jvi.00481-06  0.437
2006 Kitajima K, Marchadier DH, Miller GC, Gao GP, Wilson JM, Rader DJ. Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1852-7. PMID 16763161 DOI: 10.1161/01.Atv.0000231520.26490.54  0.538
2006 Gao GP, Lu Y, Sun X, Johnston J, Calcedo R, Grant R, Wilson JM. High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes. Journal of Virology. 80: 6192-4. PMID 16731960 DOI: 10.1128/Jvi.00526-06  0.557
2006 Zhi Y, Figueredo J, Kobinger GP, Hagan H, Calcedo R, Miller JR, Gao G, Wilson JM. Efficacy of severe acute respiratory syndrome vaccine based on a nonhuman primate adenovirus in the presence of immunity against human adenovirus. Human Gene Therapy. 17: 500-6. PMID 16716107 DOI: 10.1089/Hum.2006.17.500  0.499
2006 Bell P, Moscioni AD, McCarter RJ, Wu D, Gao G, Hoang A, Sanmiguel JC, Sun X, Wivel NA, Raper SE, Furth EE, Batshaw ML, Wilson JM. Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 34-44. PMID 16682254 DOI: 10.1016/J.Ymthe.2006.03.008  0.517
2006 Moscioni D, Morizono H, McCarter RJ, Stern A, Cabrera-Luque J, Hoang A, Sanmiguel J, Wu D, Bell P, Gao GP, Raper SE, Wilson JM, Batshaw ML. Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 25-33. PMID 16677864 DOI: 10.1016/J.Ymthe.2006.03.009  0.543
2006 Kobinger GP, Feldmann H, Zhi Y, Schumer G, Gao G, Feldmann F, Jones S, Wilson JM. Chimpanzee adenovirus vaccine protects against Zaire Ebola virus. Virology. 346: 394-401. PMID 16356525 DOI: 10.1016/J.Virol.2005.10.042  0.473
2006 Tatsis N, Tesema L, Robinson ER, Giles-Davis W, McCoy K, Gao GP, Wilson JM, Ertl HC. Chimpanzee-origin adenovirus vectors as vaccine carriers. Gene Therapy. 13: 421-9. PMID 16319951 DOI: 10.1038/Sj.Gt.3302675  0.485
2006 De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG. High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 67-76. PMID 16260185 DOI: 10.1016/J.Ymthe.2005.09.003  0.554
2006 Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Biology of AAV serotype vectors in liver-directed gene transfer to nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 77-87. PMID 16219492 DOI: 10.1016/J.Ymthe.2005.08.017  0.58
2006 Shifrin AL, Chirmule N, Gao GP, Wilson JM, Raper SE. Innate immune responses to adenoviral vector-mediated acute pancreatitis. Pancreas. 30: 122-9. PMID 15714134 DOI: 10.1097/01.Mpa.0000151578.99413.88  0.466
2006 Royo NC, Vandenberghe LH, Johnston J, Maronski M, Dichter MA, Wilson JM, Watson DJ. 900. Specific AAV Serotypes Stably Transduce Hippocampal and Cortical Cultures with High Efficiency and Low Toxicity Molecular Therapy. 13: S347. DOI: 10.1016/J.Ymthe.2006.08.989  0.607
2006 Limberis M, Calcedo R, SanMiguel J, Johnston JC, McMenamin D, Bell PL, Wilson JM. 785. A Novel Adeno Associated Virus Vector That Efficiently Transduces Airway Epithelium In Vivo and Can Be Re-Administered Molecular Therapy. 13: S304. DOI: 10.1016/J.Ymthe.2006.08.872  0.447
2006 Traube C, Heguy A, De B, Krause A, Wilson JM, Crystal RG, Worgall S. 779. Genetic Delivery of an Anti-RSV Antibody Protects Against Pulmonary Infection with RSV in Mice Molecular Therapy. 13: S301-S302. DOI: 10.1016/J.Ymthe.2006.08.866  0.388
2006 Vandenberge LH, Breous K, Gao G, McMenamin D, Munden RL, Duc TN, Wilson JM. 744. Novel Vectors for Gene Therapy: Covering the Spectrum of Primate AAV Diversity Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.826  0.587
2006 Limberis M, Vandenberghe LH, Johnston JC, Wu D, McMenamin D, Munden RL, Wilson JM. 684. Improved Performance of AAV6 in Airways In Vivo Molecular Therapy. 13: S264-S265. DOI: 10.1016/J.Ymthe.2006.08.762  0.635
2006 De BP, Hackett NR, Qiu JP, Boyer JL, Wilson JM, Crystal RG. 611. Induction of Persistent Passive Immunity Against Anthrax Toxin by an Adeno-Associated Virus Type rh10 Vector Expressing Anti-Protective Antigen Antibody Molecular Therapy. 13: S236. DOI: 10.1016/J.Ymthe.2006.08.685  0.337
2006 Somanthan S, Zhang Z, Gao G, Lock MW, Bell PL, Roy S, Sandhi AK, Wilson JM. 609. Acute-Phase Toxicity Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Mice Molecular Therapy. 13: S235. DOI: 10.1016/J.Ymthe.2006.08.683  0.503
2006 Calcedo R, Zhi Y, Figueredo JM, Franco JI, Johnston JC, Grant RL, Wilson JM. 607. Novel Adeno-Associated Viruses as Vaccine Carriers for HIV-1: Evaluation in Non-Human Primates Molecular Therapy. 13: S234-S235. DOI: 10.1016/J.Ymthe.2006.08.681  0.404
2006 Ebihara H, Qiu X, Theriault S, Klassen M, Stroeher U, Strong J, Jones S, Wilson JM, Feldmann H, Kobinger G. 604. Comparative Analysis of Different Methods for Quantitative Evaluation of Neutralizing Antibody to Ebola Virus in a Biosafety Level 2 or 4 Environment Molecular Therapy. 13: S233-S234. DOI: 10.1016/J.Ymthe.2006.08.678  0.381
2006 Croyle M, Feldmann H, Jones S, Wilson JM, Kobinger GP. 595. Nasal Delivery of Adenovirus Expressing the Ebola Glycoprotein Protects Mice Against Ebola Virus in the Presence of Preexisting Immunity to the Vaccine Carrier Molecular Therapy. 13: S230. DOI: 10.1016/J.Ymthe.2006.08.669  0.366
2006 Sun X, Lu Y, Gao G, Korn MT, SanMiguel J, Lock MW, Wilson JM. 484. Murine Liver as a Model for AAV Replication, Recombination and Evolution Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.554  0.386
2006 Bell PL, Moscioni AD, McCarter RJ, Wu D, Gao G, Hoang A, San Miguel J, Sun X, Wivel N, Raper SE, Furth EE, Batshaw ML, Wilson JM. 206. Frequency and Analysis of Liver Tumors in AAV-Treated B6C3F1 Hybrid Mice Molecular Therapy. 13: S80. DOI: 10.1016/J.Ymthe.2006.08.231  0.514
2006 Vandenberghe LH, Miller JR, Gao G, Calcedo R, Wilson JM. 116. The Proposed AAV Serotypes 10 and 11 Serologically Cross-React with AAV8 and AAV4 Molecular Therapy. 13: S47-S48. DOI: 10.1016/J.Ymthe.2006.08.136  0.675
2006 Lu Y, Sun X, Bish LT, Johnston JC, Calcedo R, Grant RL, Gao G, Wilson JM. 101. Molecular Mechanism Responsible for High Level Transgene Expression in Murine and Nonhuman Primate Liver with the Second Generation of Novel AAV Serotype Vectors Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.121  0.386
2006 Boyer JL, Kasuya K, Howard J, Hackett NR, Wilson JM, Crystal RG. 1101. Rapid and Long-Term Protection Against Anthrax Lethal Toxin Molecular Therapy. 13: S423. DOI: 10.1016/J.Ymthe.2006.08.1205  0.343
2006 Price A, Limberis M, Wilson JM, Diamond SL. 978. Reduced Immune Response to Adenovirus Vector Formulated with the Anti-Inflammatory Liposome DS/DOPE Molecular Therapy. 13: S376. DOI: 10.1016/J.Ymthe.2006.08.1071  0.396
2006 Wang L, Calcedo R, Grant R, Figueredo JM, Wilson JM. 977. Differential Host T Cell Response to the Capsid of AAV2 and 8 in Muscle-Directed Gene Transfer in Murine and Non-Human Primate Models Molecular Therapy. 13: S376. DOI: 10.1016/J.Ymthe.2006.08.1070  0.403
2006 Zhang Z, Gao G, Wetzler LM, Bell PL, Wu D, Lin J, Wilson JM. 976. TLR and MyD88 Signaling Mediates Innate Immune Responses to Adenoviral Vectors in Mouse Molecular Therapy. 13: S375-S376. DOI: 10.1016/J.Ymthe.2006.08.1069  0.348
2006 Zhang Z, Zhi Y, Figueredo JM, Calcedo R, Miller JR, Gao G, Wilson JM. 77. TLR and Myd88 Signaling Pathway Is Required for the Full Induction of Host Adaptive Immune Responses to Adenoviral Vectors and Transgenes Molecular Therapy. 13: S33. DOI: 10.1016/J.Ymthe.2006.08.094  0.5
2006 VandenDriessche T, Thorrez L, Acosta-Sanchez A, Wang L, Gillijns V, Ling M, Vandenburgh H, Mertens N, Callewaert N, Wilson J, Collen D, Chuah M. 24. Widespread and Efficient Gene Delivery to the Heart and Liver Using AAV Serotype 9: Implications for Cardiovascular Disease and Hemophilia Molecular Therapy. 13: S10-S11. DOI: 10.1016/J.Ymthe.2006.08.036  0.448
2006 Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates" (DOI:10.1016/j.ymthe.2005.08.017) Molecular Therapy. 14: 150. DOI: 10.1016/j.ymthe.2006.04.002  0.469
2005 Li Z, Qiao H, Lebherz C, Choi SR, Zhou X, Gao G, Kung HF, Rader DJ, Wilson JM, Glickson JD, Zhou R. Creatine kinase, a magnetic resonance-detectable marker gene for quantification of liver-directed gene transfer. Human Gene Therapy. 16: 1429-38. PMID 16390274 DOI: 10.1089/Hum.2005.16.1429  0.42
2005 Sterman DH, Recio A, Vachani A, Sun J, Cheung L, DeLong P, Amin KM, Litzky LA, Wilson JM, Kaiser LR, Albelda SM. Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7444-53. PMID 16243818 DOI: 10.1158/1078-0432.Ccr-05-0405  0.367
2005 Hashimoto M, Boyer JL, Hackett NR, Wilson JM, Crystal RG. Induction of protective immunity to anthrax lethal toxin with a nonhuman primate adenovirus-based vaccine in the presence of preexisting anti-human adenovirus immunity. Infection and Immunity. 73: 6885-91. PMID 16177368 DOI: 10.1128/Iai.73.10.6885-6891.2005  0.348
2005 Wilson JM. Gendicine: The First Commercial Gene Therapy Product; Chinese Translation of Editorial Human Gene Therapy. 16: 1014-1015. PMID 16149899 DOI: 10.1089/Hum.2005.16.1014  0.342
2005 Le HT, Yu QC, Wilson JM, Croyle MA. Utility of PEGylated recombinant adeno-associated viruses for gene transfer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 108: 161-77. PMID 16125817 DOI: 10.1016/J.Jconrel.2005.07.019  0.469
2005 Price A, Limberis M, Gruneich JA, Wilson JM, Diamond SL. Targeting viral-mediated transduction to the lung airway epithelium with the anti-inflammatory cationic lipid dexamethasone-spermine. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 502-9. PMID 16099413 DOI: 10.1016/J.Ymthe.2005.03.033  0.396
2005 Bell P, Wang L, Lebherz C, Flieder DB, Bove MS, Wu D, Gao GP, Wilson JM, Wivel NA. No evidence for tumorigenesis of AAV vectors in a large-scale study in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 299-306. PMID 16043099 DOI: 10.1016/J.Ymthe.2005.03.020  0.486
2005 Gao G, Vandenberghe LH, Wilson JM. New recombinant serotypes of AAV vectors. Current Gene Therapy. 5: 285-97. PMID 15975006 DOI: 10.2174/1566523054065057  0.731
2005 Bell P, Limberis M, Gao G, Wu D, Bove MS, Sanmiguel JC, Wilson JM. An optimized protocol for detection of E. coli beta-galactosidase in lung tissue following gene transfer. Histochemistry and Cell Biology. 124: 77-85. PMID 15947941 DOI: 10.1007/S00418-005-0793-2  0.482
2005 Zhi Y, Kobinger GP, Jordan H, Suchma K, Weiss SR, Shen H, Schumer G, Gao G, Boyer JL, Crystal RG, Wilson JM. Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein. Virology. 335: 34-45. PMID 15823604 DOI: 10.1016/J.Virol.2005.01.050  0.496
2005 Huszthy PC, Svendsen A, Wilson JM, Kotin RM, Lønning PE, Bjerkvig R, Hoover F. Widespread dispersion of adeno-associated virus serotype 1 and adeno-associated virus serotype 6 vectors in the rat central nervous system and in human glioblastoma multiforme xenografts. Human Gene Therapy. 16: 381-92. PMID 15812233 DOI: 10.1089/Hum.2005.16.381  0.435
2005 Lebherz C, Maguire AM, Auricchio A, Tang W, Aleman TS, Wei Z, Grant R, Cideciyan AV, Jacobson SG, Wilson JM, Bennett J. Nonhuman primate models for diabetic ocular neovascularization using AAV2-mediated overexpression of vascular endothelial growth factor. Diabetes. 54: 1141-9. PMID 15793254 DOI: 10.2337/Diabetes.54.4.1141  0.609
2005 Jennings K, Miyamae T, Traister R, Marinov A, Katakura S, Sowders D, Trapnell B, Wilson JM, Gao G, Hirsch R. Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 600-7. PMID 15771962 DOI: 10.1016/J.Ymthe.2004.10.020  0.491
2005 Lebherz C, Auricchio A, Maguire AM, Rivera VM, Tang W, Grant RL, Clackson T, Bennett J, Wilson JM. Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates. Human Gene Therapy. 16: 178-86. PMID 15761258 DOI: 10.1089/Hum.2005.16.178  0.692
2005 Boyer JL, Kobinger G, Wilson JM, Crystal RG. Adenovirus-based genetic vaccines for biodefense. Human Gene Therapy. 16: 157-68. PMID 15761256 DOI: 10.1089/Hum.2005.16.157  0.312
2005 Roy S, Clawson DS, Calcedo R, Lebherz C, Sanmiguel J, Wu D, Wilson JM. Use of chimeric adenoviral vectors to assess capsid neutralization determinants Virology. 333: 207-214. PMID 15721355 DOI: 10.1016/J.Virol.2004.12.029  0.307
2005 Varnavski AN, Calcedo R, Bove M, Gao G, Wilson JM. Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice. Gene Therapy. 12: 427-436. PMID 15647774 DOI: 10.1038/Sj.Gt.3302347  0.506
2005 Wang L, Calcedo R, Nichols TC, Bellinger DA, Dillow A, Verma IM, Wilson JM. Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy. Blood. 105: 3079-86. PMID 15637142 DOI: 10.1182/Blood-2004-10-3867  0.456
2005 Louboutin JP, Wang L, Wilson JM. Gene transfer into skeletal muscle using novel AAV serotypes. The Journal of Gene Medicine. 7: 442-51. PMID 15517544 DOI: 10.1002/Jgm.686  0.354
2005 MacKenzie TC, Kobinger GP, Louboutin JP, Radu A, Javazon EH, Sena-Esteves M, Wilson JM, Flake AW. Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors Journal of Gene Medicine. 7: 50-58. PMID 15515139 DOI: 10.1002/Jgm.649  0.322
2005 Rivera VM, Gao GP, Grant RL, Schnell MA, Zoltick PW, Rozamus LW, Clackson T, Wilson JM. Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood. 105: 1424-30. PMID 15507527 DOI: 10.1182/Blood-2004-06-2501  0.569
2005 Reyes-Sandoval A, Sridhar S, Moore AC, Gilbert SC, Gao G, Wilson JM, Hill AV. Immunogenicity of a pre-erythrocytic-stage malaria insert ME-trap encoded by novel simian adenoviral vectors Immunology. 116: 46-46. DOI: 10.1111/J.1365-2567.2005.02287.X  0.3
2005 Kobinger GP, Rowe T, Gao G, Figueredo JM, Sanmiguel J, Bell P, Hogan RJ, Wilson JM. 1092. Adenovirus-Based Vaccine Prevents Pneumonia in Ferrets Challenged with the SARS Coronavirus Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.639  0.502
2005 Zhi Y, Wu D, Jordan H, Gao G, Wilson JM. 1089. Examine the Cross-Reactivity of Vector-Specific T Cells between Human Adenoviral H5 and Simian Adenoviral C7 Vector in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.636  0.554
2005 Wang L, Calcedo R, Nichols TC, Verma IM, Wilson JM. 1081. Sustained Correction of Disease in Na|[iuml]|ve and AAV2-Pretreated Hemophilia B Dogs Using Pseudotyped AAV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.628  0.432
2005 Somanathan S, Roy S, Gao G, Sandhu A, Wilson JM. 872. Chimpanzee Derived Adenoviral Vectors Transduce and Activate Human Dendritic Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.415  0.535
2005 Boyer JL, Howard J, Hackett NR, Pergolizzi RG, Wilson JM, Crystal RG. 853. Persistent Expression of Single Chain Antibodies Mediated by AAV5 and AAVrh.10 Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.396  0.406
2005 Kelkar SA, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL. 847. Adeno-Associated Virus Capsids from Divergent AAV Clades and Subgroup C Adenovirus Capsids Share a Common Microtubule-Binding Mechanism Relevant to Virus Trafficking Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.390  0.478
2005 De BP, Heguy A, Hackett NR, Lee J, Gao G, Wilson JM, Crystal RG. 812. Non-Human Primate Serotype rh.10 AAV Directed Therapeutic Serum Levels of |[alpha]|1-antitrypsin Following Intrapleural Administration in Mice with Pre-Existing Immunity to AAV Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.349  0.431
2005 Sondhi D, Peterson DA, Vassallo E, Sanders CT, Stratton JA, Hackett NR, Gao G, Wilson JM, Crystal RG. 660. Quantitative Comparison of AAV Serotypes AAV2, AAV5, and AAVrh.10 Efficiency for CNS Gene Therapy Following Intracranial Gene Delivery Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.200  0.572
2005 De BP, Heguy A, Hackett NR, Gao G, Wilson JM, Crystal RG. 508. Impact of Sex on Serum |[alpha]|1-Antitrypsin Levels Following Intrapleural and Intravenous Administration of AAVrh.10 Vectors to Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.048  0.472
2005 Lu Y, Gao G, Sanmiguel J, Calcedo R, Bell P, Wivel N, Wilson JM. 506. Transductional and Genome Biodistribution of Novel AAV Serotype Vectors after Systemic Delivery and Their Liver Specific Dose Response Profiles in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.046  0.523
2005 Vandenberghe LH, Yang MH, Johnston J, Gao G, Wilson JM. 503. Mutational Strategy To Enhance or Rescue Functionality of Existing AAV Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.043  0.712
2005 Gao G, Lu Y, Calcedo R, Grant R, Sanmiguel J, Wang L, Johnston J, Figueredo J, Lock M, Wilson JM. 500. Biology of Novel AAV Serotype Vectors in the Liver Directed Gene Transfer to Nonhuman Primates Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.040  0.594
2005 Zhang Z, Gao GP, Wetzler LM, Zhi Y, Wilson JM. 406. Role of MyD88 Signaling Pathway in the Host Immune Responses in Adenoviral Vector-Mediated Gene Therapy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.409  0.388
2005 Zhou X, Gao G, Owens RA, Lu Y, Calcedo R, Miller J, Wilson JM. 404. Roles of Inverted Terminal Repeats (ITRs) and Capsid Proteins from Novel NHP AAVs in rAAV Mediated Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.407  0.563
2005 Limberis M, Figueredo J, Wilson JM. 146. T Cell Response Against the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.151  0.421
2005 Kobinger GP, Feldmann H, Zhi Y, Schumer G, Gao G, Feldmann F, Jones S, Wilson JM. 141. Adenovirus Vaccine to Ebola Virus: Mechanism of Protection and Impact of Pre-Existing Immunity to the Vaccine Carrier Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.146  0.502
2005 Figueredo J, Calcedo R, Miller J, Kobinger G, Grant R, Gao G, Wilson JM. 139. Priming and Boosting Efficiency of Chimp and Human Adenoviral Vectors in the Setting of Pre-Existing Immunity in Non-Human Primates Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.144  0.505
2005 Zhi Y, Johnston J, Wu D, Figueredo J, Lock M, Bell P, Gao G, Wilson JM. 112. Strong Transgene-Specific Immune Responses Can Be Elicited with Novel Adeno-Associated Virus Vectors in Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.117  0.555
2005 Wang L, Louboutin J, Li Y, Wilson JM. 111. AAV7, 8, and 9 Are More Efficient and Less Immunogenic Vectors for Muscle-Directed Gene Therapy for Hemophilia B Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.116  0.449
2004 Katakura S, Jennings K, Watanabe S, Adachi E, Thornton S, Gao GP, Wilson JM, Burstein H, Trapnell B, Hirsch R. Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy. Modern Rheumatology / the Japan Rheumatism Association. 14: 18-24. PMID 17028800 DOI: 10.1007/S10165-003-0260-7  0.536
2004 Vais H, Gao GP, Yang M, Tran P, Louboutin JP, Somanathan S, Wilson JM, Reenstra WW. Novel adenoviral vectors coding for GFP-tagged wtCFTR and ΔF508-CFTR: Characterization of expression and electrophysiological properties in A549 cells Pflugers Archiv European Journal of Physiology. 449: 278-287. PMID 15452712 DOI: 10.1007/S00424-004-1331-0  0.481
2004 Hogan RJ, Gao G, Rowe T, Bell P, Flieder D, Paragas J, Kobinger GP, Wivel NA, Crystal RG, Boyer J, Feldmann H, Voss TG, Wilson JM. Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1. Journal of Virology. 78: 11416-21. PMID 15452265 DOI: 10.1128/Jvi.78.20.11416-11421.2004  0.467
2004 Rowe T, Gao G, Hogan RJ, Crystal RG, Voss TG, Grant RL, Bell P, Kobinger GP, Wivel NA, Wilson JM. Macaque model for severe acute respiratory syndrome. Journal of Virology. 78: 11401-4. PMID 15452262 DOI: 10.1128/Jvi.78.20.11401-11404.2004  0.438
2004 Phaneuf D, Moscioni AD, LeClair C, Raper SE, Wilson JM. Generation of a mouse expressing a conditional knockout of the hepatocyte growth factor gene: demonstration of impaired liver regeneration. Dna and Cell Biology. 23: 592-603. PMID 15383179 DOI: 10.1089/Dna.2004.23.592  0.395
2004 Reyes-Sandoval A, Fitzgerald JC, Grant R, Roy S, Xiang ZQ, Li Y, Gao GP, Wilson JM, Ertl HC. Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes. Journal of Virology. 78: 7392-9. PMID 15220412 DOI: 10.1128/Jvi.78.14.7392-7399.2004  0.368
2004 Roy S, Gao G, Clawson DS, Vandenberghe LH, Farina SF, Wilson JM. Complete nucleotide sequences and genome organization of four chimpanzee adenoviruses. Virology. 324: 361-72. PMID 15207622 DOI: 10.1016/J.Virol.2004.03.047  0.659
2004 Lebherz C, Gao G, Louboutin JP, Millar J, Rader D, Wilson JM. Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia. The Journal of Gene Medicine. 6: 663-72. PMID 15170737 DOI: 10.1002/Jgm.554  0.571
2004 Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X, Wilson JM. Clades of Adeno-associated viruses are widely disseminated in human tissues. Journal of Virology. 78: 6381-8. PMID 15163731 DOI: 10.1128/Jvi.78.12.6381-6388.2004  0.705
2004 Roy S, Gao G, Lu Y, Zhou X, Lock M, Calcedo R, Wilson JM. Characterization of a family of chimpanzee adenoviruses and development of molecular clones for gene transfer vectors. Human Gene Therapy. 15: 519-30. PMID 15144581 DOI: 10.1089/10430340460745838  0.575
2004 Choi EA, Lei H, Maron DJ, Mick R, Barsoum J, Yu QC, Fraker DL, Wilson JM, Spitz FR. Combined 5-fluorouracil/systemic interferon-beta gene therapy results in long-term survival in mice with established colorectal liver metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1535-44. PMID 14977858 DOI: 10.1158/1078-0432.Ccr-0040-03  0.4
2004 Kobinger GP, Deng S, Louboutin JP, Vatamaniuk M, Matschinsky F, Markmann JF, Raper SE, Wilson JM. Transduction of human islets with pseudotyped lentiviral vectors. Human Gene Therapy. 15: 211-9. PMID 14975193 DOI: 10.1089/104303404772680010  0.406
2004 Ziegler RJ, Lonning SM, Armentano D, Li C, Souza DW, Cherry M, Ford C, Barbon CM, Desnick RJ, Gao G, Wilson JM, Peluso R, Godwin S, Carter BJ, Gregory RJ, et al. AAV2 vector harboring a liver-restricted promoter facilitates sustained expression of therapeutic levels of alpha-galactosidase A and the induction of immune tolerance in Fabry mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 231-40. PMID 14759807 DOI: 10.1016/J.Ymthe.2003.11.015  0.543
2004 Pinto AR, Fitzgerald JC, Gao GP, Wilson JM, Ertl HC. Induction of CD8+ T cells to an HIV-1 antigen upon oral immunization of mice with a simian E1-deleted adenoviral vector. Vaccine. 22: 697-703. PMID 14741162 DOI: 10.1016/J.Vaccine.2003.08.029  0.37
2004 Gao G, Lebherz C, Weiner DJ, Grant R, Calcedo R, McCullough B, Bagg A, Zhang Y, Wilson JM. Erythropoietin gene therapy leads to autoimmune anemia in macaques. Blood. 103: 3300-2. PMID 14695227 DOI: 10.1182/Blood-2003-11-3852  0.573
2004 Croyle MA, Callahan SM, Auricchio A, Schumer G, Linse KD, Wilson JM, Brunner LJ, Kobinger GP. PEGylation of a vesicular stomatitis virus G pseudotyped lentivirus vector prevents inactivation in serum. Journal of Virology. 78: 912-21. PMID 14694122 DOI: 10.1128/Jvi.78.2.912-921.2004  0.588
2004 Sarkar R, Tetreault R, Gao G, Wang L, Bell P, Chandler R, Wilson JM, Kazazian HH. Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype. Blood. 103: 1253-60. PMID 14551134 DOI: 10.1182/Blood-2003-08-2954  0.583
2004 Rivera VM, Berk L, Wardwell S, Tang H, Gao G, Grant RL, Wilson JM, Clackson T. 1048. Long-Term Regulated Gene Expression in Non-Human Primates Using a Single Non-Recombinogenic AAV Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.993  0.549
2004 Roy S, Zhi Y, Clawson D, Gao G, Kobinger GP, Wilson JM. 1016. Novel Chimeric Adenovirus Vaccine Vectors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.961  0.577
2004 Hashimoto M, Boyer JL, Hackett NR, Wilson JM, Crystal RG. 1015. Induction of Protective Immunity to Anthrax Lethal Toxin with a Chimpanzee Adenovirus-Based Vaccine Carrier in the Presence of Pre-Existing Anti-Human Adenovirus Immunity Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.960  0.33
2004 Chai N, Kobinger G, Tanzi G, Wilson J, Bates P. 732. A Novel Double-Pseudotyped Viral Vector for Gene Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.673  0.391
2004 Limberis M, Gao G, Weiner DJ, Wang L, Bell P, Wilson JM. 692. A novel AAV vector for the treatment of cystic fibrosis airway disease Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.598  0.548
2004 Zhi Y, Wang L, Gao G, Wilson JM. 569. Increased Antigen-Specific Humoral Response by Adenoviral Vector Prime and Adeno-Associated Viral Vector Boost Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.492  0.531
2004 Zhi Y, Kobinger GP, Jordan H, Gao G, Wilson JM. 568. Comparison of Antigen-Specific Immune Responses Elicited by Recombinant Simian Adenoviral Vectors with Deletions in Either E1, or E1/E3, or E1/E4 Regions Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.491  0.506
2004 Boyer J, Krause A, Qiu J, Hackett N, Kobinger G, Zhi Y, Wilson JM, Crystal RG. 558. Anti-SARS Humoral and Cellular Immunity Evoked by an Adenovirus Vector Expressing Spike Glycoprotein from SARS Coronavirus Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.485  0.375
2004 Price A, Limberis M, Gruneich J, Wilson JM, Diamond SL. 498. Targeted Gene Transfer to Lung Airway Epithelium Using Plasmid or Adenoviral Vectors Formulated with an Anti-Inflammatory Dexamethasone-Spermine Conjugate Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.427  0.383
2004 Schumer GP, Kobinger GP, Medina MF, Weiner DJ, Wilson JM. 490. Long Term Expression and Biodistribution of HIV Vector Pseudotyped with Deletion Mutant of the Ebola Envelope Glycoprotein Following Instillation in Airway of Nonhuman Primates Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.403  0.325
2004 Kobinger GP, Feldmann H, Zhi Y, Schumer GP, Gao G, Feldmann F, Jones S, Wilson JM. 373. Simian Adenoviral Vector Based-Vaccine Fully Protect Against Ebola Virus Even in the Presence of Pre-Existing Immunity to Human Adenovirus Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.317  0.508
2004 Kobinger GP, Feldmann H, Schumer GP, Wilson JM. 368. Pseudotyping HIV Vector with the Spike Envelope Protein of SARS-CoV for Studying Viral Tropism, Immunology and Gene Therapy Applications Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.305  0.318
2004 De BP, Wasif N, Hackett NR, Gao G, Wilson JM, Crystal RG. 338. Therapeutic Levels for |[alpha]|1-Antitrypsin Following Intrapleural Administration of a Non-Human Primate Serotype rh10 AAV Vector Expressing |[alpha]|1-Antitrypsin Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.280  0.517
2004 Lebherz C, Maguire AM, Auricchio A, Tang W, Aleman TS, Wei Z, Grant RL, Cideciyan AV, Jacobson SG, Wilson JM, Bennett J. 218. Nonhuman Primate Models for Retinal and Choroidal Neovascularization Using AAV2-Mediated Overexpression of Vascular Endothelial Growth Factor Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.160  0.613
2004 Wang L, Louboutin J, Nichols TC, Wilson JM. 161. Novel pseudotyped AAV vectors for hemophilia B gene therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.121  0.421
2004 Roy S, Clawson D, Lebherz C, Calcedo R, Sanmiguel J, Wu D, Wilson JM. 128. Use of chimeric adenoviral vectors to assess capsid neutralization determinants Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.084  0.409
2004 Zhou X, Gao G, Owens RA, Calcedo R, Wilson JM. 90. Evaluation of Novel Gene Transfer Vectors Derived from Infectious Molecular Clones of Primate AAVs Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.025  0.579
2004 Vandenberghe LH, Gao G, Alvira MR, Calcedo R, Wilson JM. 88. AAV clades: Their Ability To Recombine and Cross Species-Barriers Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.024  0.697
2003 Pinto AR, Fitzgerald JC, Giles-Davis W, Gao GP, Wilson JM, Ertl HC. Induction of CD8+ T cells to an HIV-1 antigen through a prime boost regimen with heterologous E1-deleted adenoviral vaccine carriers. Journal of Immunology (Baltimore, Md. : 1950). 171: 6774-9. PMID 14662882 DOI: 10.4049/Jimmunol.171.12.6774  0.372
2003 Medina MF, Kobinger GP, Rux J, Gasmi M, Looney DJ, Bates P, Wilson JM. Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 777-89. PMID 14599811 DOI: 10.1016/J.Ymthe.2003.07.003  0.414
2003 Kobinger GP, Louboutin JP, Barton ER, Sweeney HL, Wilson JM. Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells. Human Gene Therapy. 14: 1441-9. PMID 14577924 DOI: 10.1089/104303403769211655  0.356
2003 Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP, Wilson JM, Batshaw ML. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Molecular Genetics and Metabolism. 80: 148-58. PMID 14567964 DOI: 10.1016/J.Ymgme.2003.08.016  0.54
2003 Xiang Z, Li Y, Gao G, Wilson JM, Ertl HC. Mucosally delivered E1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 4287-93. PMID 14530353 DOI: 10.4049/Jimmunol.171.8.4287  0.522
2003 Xiang ZQ, Gao GP, Reyes-Sandoval A, Li Y, Wilson JM, Ertl HC. Oral vaccination of mice with adenoviral vectors is not impaired by preexisting immunity to the vaccine carrier. Journal of Virology. 77: 10780-9. PMID 14512528 DOI: 10.1128/Jvi.77.20.10780-10789.2003  0.379
2003 Gao G, Zhou X, Alvira MR, Tran P, Marsh J, Lynd K, Xiao W, Wilson JM. High throughput creation of recombinant adenovirus vectors by direct cloning, green-white selection and I-Sce I-mediated rescue of circular adenovirus plasmids in 293 cells. Gene Therapy. 10: 1926-30. PMID 14502222 DOI: 10.1038/Sj.Gt.3302088  0.66
2003 Wang X, Zhang Z, Louboutin JP, Moser C, Weiner DJ, Wilson JM. Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1727-9. PMID 12958190 DOI: 10.1096/Fj.02-0616Fje  0.489
2003 Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN, Maguire AM, Wilson JM, Bennett J. Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. Journal of Virology. 77: 7957-63. PMID 12829835 DOI: 10.1128/Jvi.77.14.7957-7963.2003  0.665
2003 Lim FY, Kobinger GP, Weiner DJ, Radu A, Wilson JM, Crombleholme TM. Human fetal trachea-SCID mouse xenografts: efficacy of vesicular stomatitis virus-G pseudotyped lentiviral-mediated gene transfer. Journal of Pediatric Surgery. 38: 834-9. PMID 12778376 DOI: 10.1016/S0022-3468(03)00106-4  0.432
2003 Johnston J, Tazelaar J, Rivera VM, Clackson T, Gao GP, Wilson JM. Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 493-7. PMID 12727112 DOI: 10.1016/S1525-0016(03)00043-1  0.559
2003 Varnavski AN, Schlienger K, Bergelson JM, Gao GP, Wilson JM. Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector. Human Gene Therapy. 14: 533-44. PMID 12718764 DOI: 10.1089/104303403764539323  0.511
2003 Gao G, Alvira MR, Somanathan S, Lu Y, Vandenberghe LH, Rux JJ, Calcedo R, Sanmiguel J, Abbas Z, Wilson JM. Adeno-associated viruses undergo substantial evolution in primates during natural infections. Proceedings of the National Academy of Sciences of the United States of America. 100: 6081-6. PMID 12716974 DOI: 10.1073/Pnas.0937739100  0.69
2003 Gruss CJ, Satyamoorthy K, Berking C, Lininger J, Nesbit M, Schaider H, Liu ZJ, Oka M, Hsu MY, Shirakawa T, Li G, Bogenrieder T, Carmeliet P, El-Deiry WS, Eck SL, ... ... Wilson JM, et al. Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. The Journal of Investigative Dermatology. 120: 683-92. PMID 12648235 DOI: 10.1046/J.1523-1747.2003.12112.X  0.311
2003 Auricchio A, Acton PD, Hildinger M, Louboutin JP, Plössl K, O'Connor E, Kung HF, Wilson JM. In vivo quantitative noninvasive imaging of gene transfer by single-photon emission computerized tomography. Human Gene Therapy. 14: 255-61. PMID 12639305 DOI: 10.1089/10430340360535805  0.588
2003 Xiang ZQ, Gao GP, Li Y, Wilson JM, Ertl HC. T helper cell-independent antibody responses to the transgene product of an e1-deleted adenoviral vaccine require NK1.1 T cells. Virology. 305: 397-405. PMID 12573585 DOI: 10.1006/Viro.2002.1700  0.335
2003 Reich SJ, Auricchio A, Hildinger M, Glover E, Maguire AM, Wilson JM, Bennett J. Efficient trans-splicing in the retina expands the utility of adeno-associated virus as a vector for gene therapy. Human Gene Therapy. 14: 37-44. PMID 12573057 DOI: 10.1089/10430340360464697  0.709
2003 Fitzgerald JC, Gao GP, Reyes-Sandoval A, Pavlakis GN, Xiang ZQ, Wlazlo AP, Giles-Davis W, Wilson JM, Ertl HC. A simian replication-defective adenoviral recombinant vaccine to HIV-1 gag. Journal of Immunology (Baltimore, Md. : 1950). 170: 1416-22. PMID 12538702 DOI: 10.4049/Jimmunol.170.3.1416  0.496
2003 Vinner L, Wee EG, Patel S, Corbet S, Gao GP, Nielsen C, Wilson JM, Ertl HC, Hanke T, Fomsgaard A. Immunogenicity in Mamu-A*01 rhesus macaques of a CCR5-tropic human immunodeficiency virus type 1 envelope from the primary isolate (Bx08) after synthetic DNA prime and recombinant adenovirus 5 boost. The Journal of General Virology. 84: 203-13. PMID 12533717 DOI: 10.1099/Vir.0.18589-0  0.319
2003 Keswani S, Katz A, Lim F, Zoltick P, Kobinger G, Radu A, Wilson J, Weiner D, Crombleholme T. Human fetal trachea xenografts recapitulate normal development: implications for fetal gene therapy using pseudotyped AAV vectors Journal of Surgical Research. 114: 261. DOI: 10.1016/J.Jss.2003.08.197  0.336
2002 Green AP, Huang JJ, Scott MO, Kierstead TD, Beaupré I, Gao GP, Wilson JM. A new scalable method for the purification of recombinant adenovirus vectors. Human Gene Therapy. 13: 1921-34. PMID 12427304 DOI: 10.1089/10430340260355338  0.498
2002 Croyle MA, Chirmule N, Zhang Y, Wilson JM. PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver. Human Gene Therapy. 13: 1887-900. PMID 12396620 DOI: 10.1089/104303402760372972  0.464
2002 Auricchio A, Behling KC, Maguire AM, O'Connor EM, Bennett J, Wilson JM, Tolentino MJ. Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 490-4. PMID 12377190 DOI: 10.1006/Mthe.2002.0702  0.658
2002 MacKenzie TC, Kobinger GP, Kootstra NA, Radu A, Sena-Esteves M, Bouchard S, Wilson JM, Verma IM, Flake AW. Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes Molecular Therapy. 6: 349-358. PMID 12231171 DOI: 10.1006/Mthe.2002.0681  0.418
2002 Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 99: 11854-9. PMID 12192090 DOI: 10.1073/Pnas.182412299  0.598
2002 Auricchio A, O'Connor E, Weiner D, Gao GP, Hildinger M, Wang L, Calcedo R, Wilson JM. Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins. The Journal of Clinical Investigation. 110: 499-504. PMID 12189244 DOI: 10.1172/Jci15780  0.681
2002 Auricchio A, Rivera VM, Clackson T, O'Connor EE, Maguire AM, Tolentino MJ, Bennett J, Wilson JM. Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 238-42. PMID 12161190 DOI: 10.1006/Mthe.2002.0660  0.664
2002 Hoshijima M, Ikeda Y, Iwanaga Y, Minamisawa S, Date MO, Gu Y, Iwatate M, Li M, Wang L, Wilson JM, Wang Y, Ross J, Chien KR. Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nature Medicine. 8: 864-71. PMID 12134142 DOI: 10.1038/Nm739  0.336
2002 Auricchio A, Gao GP, Yu QC, Raper S, Rivera VM, Clackson T, Wilson JM. Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer. Gene Therapy. 9: 963-71. PMID 12085245 DOI: 10.1038/sj.gt.3301746  0.487
2002 Varnavski AN, Zhang Y, Schnell M, Tazelaar J, Louboutin JP, Yu QC, Bagg A, Gao GP, Wilson JM. Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity. Journal of Virology. 76: 5711-9. PMID 11991999 DOI: 10.1128/Jvi.76.11.5711-5719.2002  0.535
2002 Gao GP, Lu F, Sanmiguel JC, Tran PT, Abbas Z, Lynd KS, Marsh J, Spinner NB, Wilson JM. Rep/Cap gene amplification and high-yield production of AAV in an A549 cell line expressing Rep/Cap. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 644-9. PMID 11991756 DOI: 10.1006/Mthe.2001.0591  0.516
2002 Watson DJ, Kobinger GP, Passini MA, Wilson JM, Wolfe JH. Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 528-37. PMID 11991743 DOI: 10.1006/Mthe.2002.0584  0.387
2002 Gonzalez-Aseguinolaza G, Van Kaer L, Bergmann CC, Wilson JM, Schmieg J, Kronenberg M, Nakayama T, Taniguchi M, Koezuka Y, Tsuji M. Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines. The Journal of Experimental Medicine. 195: 617-24. PMID 11877484 DOI: 10.1084/Jem.20011889  0.31
2002 Xiang Z, Gao G, Reyes-Sandoval A, Cohen CJ, Li Y, Bergelson JM, Wilson JM, Ertl HC. Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. Journal of Virology. 76: 2667-75. PMID 11861833 DOI: 10.1128/Jvi.76.6.2667-2675.2002  0.499
2002 Zoltick PW, Wilson JM. Regulated gene expression in gene therapy. Annals of the New York Academy of Sciences. 953: 53-63. PMID 11795423 DOI: 10.1111/J.1749-6632.2001.Tb11360.X  0.409
2002 Raper SE, Yudkoff M, Chirmule N, Gao GP, Nunes F, Haskal ZJ, Furth EE, Propert KJ, Robinson MB, Magosin S, Simoes H, Speicher L, Hughes J, Tazelaar J, Wivel NA, ... Wilson JM, et al. A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency. Human Gene Therapy. 13: 163-75. PMID 11779420 DOI: 10.1089/10430340152712719  0.528
2002 Wang X, Moser C, Louboutin JP, Lysenko ES, Weiner DJ, Weiser JN, Wilson JM. Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung. Journal of Immunology (Baltimore, Md. : 1950). 168: 810-5. PMID 11777976 DOI: 10.4049/Jimmunol.168.2.810  0.465
2002 Cohen CJ, Xiang ZQ, Gao GP, Ertl HC, Wilson JM, Bergelson JM. Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor. The Journal of General Virology. 83: 151-5. PMID 11752711 DOI: 10.1099/0022-1317-83-1-151  0.523
2001 Auricchio A, Kobinger G, Anand V, Hildinger M, O'Connor E, Maguire AM, Wilson JM, Bennett J. Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. Human Molecular Genetics. 10: 3075-81. PMID 11751689 DOI: 10.1093/Hmg/10.26.3075  0.702
2001 Farina SF, Gao GP, Xiang ZQ, Rux JJ, Burnett RM, Alvira MR, Marsh J, Ertl HC, Wilson JM. Replication-defective vector based on a chimpanzee adenovirus. Journal of Virology. 75: 11603-13. PMID 11689642 DOI: 10.1128/Jvi.75.23.11603-11613.2001  0.519
2001 Auricchio A, O'Connor E, Hildinger M, Wilson JM. A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 372-4. PMID 11592841 DOI: 10.1006/Mthe.2001.0462  0.57
2001 Croyle MA, Cheng X, Wilson JM. Development of formulations that enhance physical stability of viral vectors for gene therapy Gene Therapy. 8: 1281-1290. PMID 11571564 DOI: 10.1038/Sj.Gt.3301527  0.376
2001 Maron DJ, Tada H, Moscioni AD, Tazelaar J, Fraker DL, Wilson JM, Spitz FR. Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 29-35. PMID 11472103 DOI: 10.1006/Mthe.2001.0417  0.327
2001 Croyle MA, Cheng X, Sandhu A, Wilson JM. Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 22-8. PMID 11472102 DOI: 10.1006/Mthe.2001.0411  0.451
2001 Davis AR, Wivel NA, Palladino JL, Tao L, Wilson JM. Construction of adenoviral vectors. Molecular Biotechnology. 18: 63-70. PMID 11439700 DOI: 10.1385/Mb:18:1:63  0.373
2001 Tada H, Maron DJ, Choi EA, Barsoum J, Lei H, Xie Q, Liu W, Ellis L, Moscioni AD, Tazelaar J, Fawell S, Qin X, Propert KJ, Davis A, Fraker DL, ... Wilson JM, et al. Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases. The Journal of Clinical Investigation. 108: 83-95. PMID 11435460 DOI: 10.1172/Jci9841  0.357
2001 Ye X, Zimmer KP, Brown R, Pabin C, Batshaw ML, Wilson JM, Robinson MB. Differences in the human and mouse amino-terminal leader peptides of ornithine transcarbamylase affect mitochondrial import and efficacy of adenoviral vectors. Human Gene Therapy. 12: 1035-46. PMID 11399226 DOI: 10.1089/104303401750214267  0.4
2001 Hildinger M, Auricchio A, Gao G, Wang L, Chirmule N, Wilson JM. Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer. Journal of Virology. 75: 6199-203. PMID 11390622 DOI: 10.1128/Jvi.75.13.6199-6203.2001  0.676
2001 Schnell MA, Zhang Y, Tazelaar J, Gao GP, Yu QC, Qian R, Chen SJ, Varnavski AN, LeClair C, Raper SE, Wilson JM. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 708-22. PMID 11356076 DOI: 10.1006/Mthe.2001.0330  0.538
2001 Zoltick PW, Chirmule N, Schnell MA, Gao G, Hughes JV, Wilson JM. Biology of E1-Deleted Adenovirus Vectors in Nonhuman Primate Muscle Journal of Virology. 75: 5222-5229. PMID 11333904 DOI: 10.1128/Jvi.75.11.5222-5229.2001  0.575
2001 Dejneka NS, Auricchio A, Maguire AM, Ye X, Gao GP, Wilson JM, Bennett J. Pharmacologically regulated gene expression in the retina following transduction with viral vectors. Gene Therapy. 8: 442-6. PMID 11313822 DOI: 10.1038/sj.gt.3301413  0.546
2001 Croyle MA, Chirmule N, Zhang Y, Wilson JM. "Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung. Journal of Virology. 75: 4792-801. PMID 11312351 DOI: 10.1128/Jvi.75.10.4792-4801.2001  0.489
2001 Auricchio A, Zhou R, Wilson JM, Glickson JD. In vivo detection of gene expression in liver by 31P nuclear magnetic resonance spectroscopy employing creatine kinase as a marker gene. Proceedings of the National Academy of Sciences of the United States of America. 98: 5205-10. PMID 11296261 DOI: 10.1073/Pnas.081508598  0.598
2001 Wilson JM. Adenovirus-mediated gene transfer to liver11The article was originally published in Advanced Drug Delivery Reviews 17 (1995) 303–307. Advanced Drug Delivery Reviews. 46: 205-209. PMID 11259841 DOI: 10.1016/S0169-409X(00)00125-3  0.307
2001 Kobinger GP, Weiner DJ, Yu QC, Wilson JM. Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo. Nature Biotechnology. 19: 225-30. PMID 11231554 DOI: 10.1038/85664  0.396
2001 Cordier L, Gao GP, Hack AA, McNally EM, Wilson JM, Chirmule N, Sweeney HL. Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies. Human Gene Therapy. 12: 205-15. PMID 11177557 DOI: 10.1089/104303401750061267  0.558
2001 Auricchio A, Hildinger M, O'Connor E, Gao GP, Wilson JM. Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. Human Gene Therapy. 12: 71-6. PMID 11177544 DOI: 10.1089/104303401450988  0.661
2001 Chen SJ, Tazelaar J, Wilson JM. Selective repopulation of normal mouse liver by hepatocytes transduced in vivo with recombinant adeno-associated virus. Human Gene Therapy. 12: 45-50. PMID 11177541 DOI: 10.1089/104303401450951  0.432
2001 Tao N, Gao GP, Parr M, Johnston J, Baradet T, Wilson JM, Barsoum J, Fawell SE. Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 28-35. PMID 11162308 DOI: 10.1006/Mthe.2000.0227  0.508
2001 Zoltick PW, Wilson JM. A quantitative nonimmunogenic transgene product for evaluating vectors in nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 657-9. PMID 11124068 DOI: 10.1006/Mthe.2000.0204  0.366
2001 Gao GP, Wilson JM, Wivel NA. Production of recombinant adeno-associated virus. Advances in Virus Research. 55: 529-43. PMID 11050955 DOI: 10.1016/S0065-3527(00)55016-7  0.585
2001 Jennings K, Katakura S, Burstein H, Gao G, Wilson J, Hirsch R. Adeno-associated virus preferentially transduces human compared to mouse synovium Arthritis Research & Therapy. 3: 1-14. DOI: 10.1186/Ar334  0.557
2000 Sterman DH, Molnar-Kimber K, Iyengar T, Chang M, Lanuti M, Amin KM, Pierce BK, Kang E, Treat J, Recio A, Litzky L, Wilson JM, Kaiser LR, Albelda SM. A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma. Cancer Gene Therapy. 7: 1511-8. PMID 11228529 DOI: 10.1038/Sj.Cgt.7700269  0.379
2000 Zhou T, Guo JT, Nunes FA, Molnar-Kimber KL, Wilson JM, Aldrich CE, Saputelli J, Litwin S, Condreay LD, Seeger C, Mason WS. Combination therapy with lamivudine and adenovirus causes transient suppression of chronic woodchuck hepatitis virus infections. Journal of Virology. 74: 11754-63. PMID 11090175 DOI: 10.1128/Jvi.74.24.11754-11763.2000  0.341
2000 Ye X, Robinson MB, Pabin C, Batshaw ML, Wilson JM. Transient depletion of CD4 lymphocyte improves efficacy of repeated administration of recombinant adenovirus in the ornithine transcarbamylase deficient sparse fur mouse. Gene Therapy. 7: 1761-7. PMID 11083498 DOI: 10.1038/Sj.Gt.3301299  0.409
2000 Gao G, Qu G, Burnham MS, Huang J, Chirmule N, Joshi B, Yu QC, Marsh JA, Conceicao CM, Wilson JM. Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo Human Gene Therapy. 11: 2079-2091. PMID 11044910 DOI: 10.1089/104303400750001390  0.557
2000 Chen SJ, Rader DJ, Tazelaar J, Kawashiri M, Gao G, Wilson JM. Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 256-61. PMID 10985956 DOI: 10.1006/Mthe.2000.0122  0.521
2000 Croyle MA, Yu QC, Wilson JM. Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions. Human Gene Therapy. 11: 1713-22. PMID 10954905 DOI: 10.1089/10430340050111368  0.347
2000 Watanabe S, Imagawa T, Boivin GP, Gao G, Wilson JM, Hirsch R. Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 147-52. PMID 10947942 DOI: 10.1006/Mthe.2000.0111  0.542
2000 Chen SJ, Tazelaar J, Moscioni AD, Wilson JM. In vivo selection of hepatocytes transduced with adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 414-22. PMID 10933962 DOI: 10.1006/Mthe.2000.0065  0.43
2000 Xiao W, Chirmule N, Schnell MA, Tazelaar J, Hughes JV, Wilson JM. Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 323-9. PMID 10933950 DOI: 10.1006/Mthe.2000.0045  0.553
2000 Cordier L, Hack AA, Scott MO, Barton-Davis ER, Gao G, Wilson JM, McNally EM, Sweeney HL. Rescue of skeletal muscles of gamma-sarcoglycan-deficient mice with adeno-associated virus-mediated gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 119-29. PMID 10933922 DOI: 10.1006/Mthe.1999.0019  0.355
2000 Zhang Y, Chirmule N, Gao G, Wilson J. CD40 Ligand-Dependent Activation of Cytotoxic T Lymphocytes by Adeno-Associated Virus Vectors In Vivo: Role of Immature Dendritic Cells Journal of Virology. 74: 8003-8010. PMID 10933709 DOI: 10.1128/Jvi.74.17.8003-8010.2000  0.571
2000 Davis AR, Wivel NA, Palladino JL, Tao L, Wilson JM. Construction of adenoviral vectors. Methods of Molecular Biology. 135: 515-523. PMID 10791346 DOI: 10.1385/1-59259-685-1:515  0.373
2000 Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Brenner M, Oldfield E, Gansbacher B, et al. Human gene marker/therapy clinical protocols. Human Gene Therapy. 11: 919-79. PMID 10779168 DOI: 10.1089/10430340050015536  0.361
2000 Chirmule N, Raper SE, Burkly L, Thomas D, Tazelaar J, Hughes JV, Wilson JM. Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions. Journal of Virology. 74: 3345-3352. PMID 10708452 DOI: 10.1128/Jvi.74.7.3345-3352.2000  0.353
2000 Chirmule N, Xiao W, Truneh A, Schnell MA, Hughes JV, Zoltick P, Wilson JM. Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle. Journal of Virology. 74: 2420-5. PMID 10666273 DOI: 10.1128/Jvi.74.5.2420-2425.2000  0.568
2000 Caplan AL, Wilson JM. The ethical challenges of in utero gene therapy. Nature Genetics. 24: 107-107. PMID 10655050 DOI: 10.1038/72747  0.374
2000 Gao GP, Engdahl RK, Wilson JM. A cell line for high-yield production of E1-deleted adenovirus vectors without the emergence of replication-competent virus. Human Gene Therapy. 11: 213-9. PMID 10646652 DOI: 10.1089/10430340050016283  0.528
2000 Yu Q, Ma X, Croyle M, Qu G, Huang J, Gao G, Hughes J, Wilson J. Electron Microscopic Evaluation of Vector Quality for Gene Therapy Microscopy and Microanalysis. 6: 858-859. DOI: 10.1017/S1431927600036783  0.49
2000 Shifrin AL, Auricchio A, Wilson J, Raper SE. Correction of hyperglycemia by adenoviral vector-mediated insulin gene expression in the murine pancreas Journal of the American College of Surgeons. 191: S31. DOI: 10.1016/S1072-7515(00)00463-4  0.546
2000 Phaneuf D, Chen S, Wilson JM. Intravenous injection of an adenovirus encoding hepatocyte growth factor results in liver growth and has a protective effect against apoptosis. Molecular Medicine. 6: 96-103. DOI: 10.1007/Bf03401777  0.331
1999 Skorupa AF, Fisher KJ, Wilson JM, Parente MK, Wolfe JH. Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice. Experimental Neurology. 160: 17-27. PMID 10630187 DOI: 10.1006/Exnr.1999.7176  0.385
1999 Zuckerman JB, Robinson CB, McCoy KS, Shell R, Sferra TJ, Chirmule N, Magosin SA, Propert KJ, Brown-Parr EC, Hughes JV, Tazelaar J, Baker C, Goldman MJ, Wilson JM. A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis. Human Gene Therapy. 10: 2973-85. PMID 10609658 DOI: 10.1089/10430349950016384  0.449
1999 Chirmule N, Moffett J, Dhagat P, Tazelaar J, Wilson JM. Adenoviral vector-mediated gene therapy in the mouse lung: no role of Fas-Fas ligand interactions for elimination of transgene expression in bronchioepithelial cells. Human Gene Therapy. 10: 2839-46. PMID 10584929 DOI: 10.1089/10430349950016564  0.399
1999 Grifman M, Chen NN, Gao GP, Cathomen T, Wilson JM, Weitzman MD. Overexpression of cyclin A inhibits augmentation of recombinant adeno-associated virus transduction by the adenovirus E4orf6 protein. Journal of Virology. 73: 10010-9. PMID 10559315 DOI: 10.1128/Jvi.73.12.10010-10019.1999  0.66
1999 Nunes FA, Furth EE, Wilson JM, Raper SE. Gene transfer into the liver of nonhuman primates with E1-deleted recombinant adenoviral vectors: safety of readministration. Human Gene Therapy. 10: 2515-26. PMID 10543616 DOI: 10.1089/10430349950016852  0.425
1999 Batshaw ML, Robinson MB, Ye X, Pabin C, Daikhin Y, Burton BK, Wilson JM, Yudkoff M. Correction of ureagenesis after gene transfer in an animal model and after liver transplantation in humans with ornithine transcarbamylase deficiency. Pediatric Research. 46: 588-93. PMID 10541323 DOI: 10.1203/00006450-199911000-00016  0.341
1999 Bals R, Weiner DJ, Moscioni AD, Meegalla RL, Wilson JM. Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide. Infection and Immunity. 67: 6084-9. PMID 10531270 DOI: 10.1128/Iai.67.11.6084-6089.1999  0.316
1999 Batshaw ML, Wilson JM, Raper S, Yudkoff M, Robinson MB. Recombinant adenovirus gene transfer in adults with partial ornithine transcarbamylase deficiency (OTCD). Human Gene Therapy. 10: 2419-37. PMID 10515461 DOI: 10.1089/10430349950017068  0.348
1999 Chirmule N, Propert KJ, Magosin SA, Qian Y, Qian R, Wilson JM. Immune responses to adenovirus and adeno-associated virus in humans Gene Therapy. 6: 1574-1583. PMID 10490767 DOI: 10.1038/Sj.Gt.3300994  0.404
1999 Bennett J, Maguire AM, Cideciyan AV, Schnell M, Glover E, Anand V, Aleman TS, Chirmule N, Gupta AR, Huang Y, Gao GP, Nyberg WC, Tazelaar J, Hughes J, Wilson JM, et al. Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proceedings of the National Academy of Sciences of the United States of America. 96: 9920-5. PMID 10449795 DOI: 10.1073/Pnas.96.17.9920  0.66
1999 Simon PD, Vorwerk CK, Mansukani SS, Chen SJ, Wilson JM, Zurakowski D, Bennett J, Dreyer EB. bcl-2 gene therapy exacerbates excitotoxicity. Human Gene Therapy. 10: 1715-20. PMID 10428216 DOI: 10.1089/10430349950017716  0.501
1999 Rivera VM, Ye X, Courage NL, Sachar J, Cerasoli F, Wilson JM, Gilman M. Long-term regulated expression of growth hormone in mice after intramuscular gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 96: 8657-62. PMID 10411931 DOI: 10.1073/Pnas.96.15.8657  0.442
1999 Dudus L, Anand V, Acland GM, Chen SJ, Wilson JM, Fisher KJ, Maguire AM, Bennett J. Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV. Vision Research. 39: 2545-53. PMID 10396623 DOI: 10.1016/S0042-6989(98)00308-3  0.525
1999 Bals R, Wang X, Meegalla RL, Wattler S, Weiner DJ, Nehls MC, Wilson JM. Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infection and Immunity. 67: 3542-7. PMID 10377137 DOI: 10.1128/Iai.67.7.3542-3547.1999  0.503
1999 Bals R, Xiao W, Sang N, Weiner DJ, Meegalla RL, Wilson JM. Transduction of well-differentiated airway epithelium by recombinant adeno-associated virus is limited by vector entry. Journal of Virology. 73: 6085-8. PMID 10364362 DOI: 10.1128/Jvi.73.7.6085-6088.1999  0.546
1999 Bals R, Weiner DJ, Meegalla RL, Wilson JM. Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. The Journal of Clinical Investigation. 103: 1113-7. PMID 10207162 DOI: 10.1172/Jci6570  0.339
1999 Greelish JP, Su LT, Lankford EB, Burkman JM, Chen H, Konig SK, Mercier IM, Desjardins PR, Mitchell MA, Zheng XG, Leferovich J, Gao GP, Balice-Gordon RJ, Wilson JM, Stedman HH. Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vector. Nature Medicine. 5: 439-43. PMID 10202936 DOI: 10.1038/7439  0.386
1999 Xiao W, Chirmule N, Berta SC, McCullough B, Gao G, Wilson JM. Gene therapy vectors based on adeno-associated virus type 1. Journal of Virology. 73: 3994-4003. PMID 10196295 DOI: 10.1128/Jvi.73.5.3994-4003.1999  0.681
1999 Yang EY, Cass DL, Sylvester KG, Wilson JM, Adzick NS. BAPS Prize--1997. Fetal gene therapy: efficacy, toxicity, and immunologic effects of early gestation recombinant adenovirus. British Association of Paediatric Surgeons. Journal of Pediatric Surgery. 34: 235-41. PMID 10052795 DOI: 10.1016/S0022-3468(99)90181-1  0.406
1999 Lanuti M, Gao GP, Force SD, Chang MY, El Kouri C, Amin KM, Hughes JV, Wilson JM, Kaiser LR, Albelda SM. Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy. Human Gene Therapy. 10: 463-75. PMID 10048398 DOI: 10.1089/10430349950018904  0.575
1999 Chirmule N, Moscioni AD, Qian Y, Qian R, Chen Y, Wilson JM. Fas-Fas ligand interactions play a major role in effector functions of cytotoxic T lymphocytes after adenovirus vector-mediated gene transfer. Human Gene Therapy. 10: 259-69. PMID 10022550 DOI: 10.1089/10430349950019048  0.411
1999 Bals R, Weiner DJ, Wilson JM. The innate immune system in cystic fibrosis lung disease. The Journal of Clinical Investigation. 103: 303-7. PMID 9927489 DOI: 10.1172/Jci6277  0.348
1999 Ye X, Rivera VM, Zoltick P, Cerasoli F, Schnell MA, Gao G, Hughes JV, Gilman M, Wilson JM. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer. Science (New York, N.Y.). 283: 88-91. PMID 9872748 DOI: 10.1126/Science.283.5398.88  0.554
1999 Rodrigues EG, Zavala F, Nussenzweig RS, Wilson JM, Tsuji M. Efficient induction of protective anti-malaria immunity by recombinant adenovirus. Vaccine. 16: 1812-7. PMID 9795385 DOI: 10.1016/S0264-410X(98)00181-9  0.345
1999 Ye X, Sachar J, Lisska E, Xiao W, Robinson MB, Wilson JM, Batshaw ML. Adeno-Associated Virus(AAV)-Mediated Expression of Ornithine Transcarbamylase (OTC) in OTC Deficient spf-ash mMice Pediatric Research. 45: 142A-142A. DOI: 10.1203/00006450-199904020-00845  0.513
1999 Wivel NA, Gao G, Wilson JM. 5 Adenovirus Vectors Cold Spring Harbor Monograph Archive. 36: 87-110. DOI: 10.1101/087969528.36.87  0.577
1999 Wilson JM. Constitutive and Regulated Expression in the Systemic Delivery of Erythropoietin Following Skeletal Muscle Transduction with DNA Viral Vectors Nature Biotechnology. 17: 13-13. DOI: 10.1038/70127  0.311
1999 Zimmer KP, Bendiks M, Mori M, Kominami E, Robinson MB, Ye X, Wilson JM. Efficient Mitochondrial Import of Newly Synthesized Ornithine Transcarbamylase (OTC) and Correction of Secondary Metabolic Alterations in spfash Mice following Gene Therapy of OTC Deficiency Molecular Medicine. 5: 244-253. DOI: 10.1007/Bf03402122  0.359
1998 Davis AR, Meyers K, Wilson JM. High throughput method for creating and screening recombinant adenoviruses Gene Therapy. 5: 1148-1152. PMID 10326039 DOI: 10.1038/Sj.Gt.3300705  0.418
1998 Gao GP, Qu G, Faust LZ, Engdahl RK, Xiao W, Hughes JV, Zoltick PW, Wilson JM. High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus. Human Gene Therapy. 9: 2353-62. PMID 9829534 DOI: 10.1089/Hum.1998.9.16-2353  0.661
1998 Qin X, Tao N, Dergay A, Moy P, Fawell S, Davis A, Wilson JM, Barsoum J. Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 14411-14416. PMID 9826714 DOI: 10.1073/Pnas.95.24.14411  0.317
1998 Xiao W, Berta SC, Lu MM, Moscioni AD, Tazelaar J, Wilson JM. Adeno-associated virus as a vector for liver-directed gene therapy. Journal of Virology. 72: 10222-6. PMID 9811765 DOI: 10.1128/Jvi.72.12.10222-10226.1998  0.567
1998 Ye X, Gao GP, Pabin C, Raper SE, Wilson JM. Evaluating the potential of germ line transmission after intravenous administration of recombinant adenovirus in the C3H mouse. Human Gene Therapy. 9: 2135-42. PMID 9759939 DOI: 10.1089/Hum.1998.9.14-2135  0.338
1998 Molnar-Kimber KL, Sterman DH, Chang M, Kang EH, ElBash M, Lanuti M, Elshami A, Gelfand K, Wilson JM, Kaiser LR, Albelda SM. Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. Human Gene Therapy. 9: 2121-33. PMID 9759938 DOI: 10.1089/Hum.1998.9.14-2121  0.383
1998 Bals R, Wang X, Zasloff M, Wilson JM. The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proceedings of the National Academy of Sciences of the United States of America. 95: 9541-6. PMID 9689116 DOI: 10.1073/Pnas.95.16.9541  0.454
1998 Raper SE, Wilson JM, Yudkoff M, Robinson MB, Ye X, Batshaw ML. Developing adenoviral-mediated in vivo gene therapy for ornithine transcarbamylase deficiency. Journal of Inherited Metabolic Disease. 21: 119-37. PMID 9686350 DOI: 10.1023/A:1005369926784  0.466
1998 Wivel NA, Wilson JM. Methods of gene delivery. Hematology/Oncology Clinics of North America. 12: 483-501. PMID 9684094 DOI: 10.1016/S0889-8588(05)70004-6  0.408
1998 Chirmule N, Hughes JV, Gao G, Raper SE, Wilson JM. Role of E4 in Eliciting CD4 T-Cell and B-Cell Responses to Adenovirus Vectors Delivered to Murine and Nonhuman Primate Lungs Journal of Virology. 72: 6138-6145. PMID 9621078 DOI: 10.1128/Jvi.72.7.6138-6145.1998  0.508
1998 Jooss K, Turka L, Wilson J. Blunting of immune responses to adenoviral vectors in mouse liver and lung with CTLA4Ig Gene Therapy. 5: 309-319. PMID 9614550 DOI: 10.1038/Sj.Gt.3300595  0.445
1998 Sterman DH, Treat J, Litzky LA, Amin KM, Coonrod L, Molnar-Kimber K, Recio A, Knox L, Wilson JM, Albelda SM, Kaiser LR. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Human Gene Therapy. 9: 1083-92. PMID 9607419 DOI: 10.1089/Hum.1998.9.7-1083  0.405
1998 Jooss K, Yang Y, Fisher KJ, Wilson JM. Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers. Journal of Virology. 72: 4212-23. PMID 9557710 DOI: 10.1128/Jvi.72.5.4212-4223.1998  0.447
1998 Raper SE, Haskal ZJ, Ye X, Pugh C, Furth EE, Gao GP, Wilson JM. Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses. Human Gene Therapy. 9: 671-9. PMID 9551615 DOI: 10.1089/Hum.1998.9.5-671  0.528
1998 Jooss K, Ertl HCJ, Wilson JM. Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver Journal of Virology. 72: 2945-2954. PMID 9525615 DOI: 10.1128/Jvi.72.4.2945-2954.1998  0.444
1998 Bals R, Goldman MJ, Wilson JM. Mouse β-Defensin 1 Is a Salt-Sensitive Antimicrobial Peptide Present in Epithelia of the Lung and Urogenital Tract Infection and Immunity. 66: 1225-1232. PMID 9488417 DOI: 10.1128/Iai.66.3.1225-1232.1998  0.305
1998 Goldman MJ, Lee PS, Yang JS, Wilson JM. Lentiviral vectors for gene therapy of cystic fibrosis. Human Gene Therapy. 8: 2261-8. PMID 9449379 DOI: 10.1089/Hum.1997.8.18-2261  0.41
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