| Year |
Citation |
Score |
| 2021 |
Dimond ZE, Suchland RJ, Baid S, Labrie SD, Soules KR, Stanley J, Carrell S, Kwong F, Wang Y, Rockey DD, Hybiske K, Hefty PS. Inter-species lateral gene transfer focused on the Chlamydia plasticity zone identifies loci associated with immediate cytotoxicity and inclusion stability. Molecular Microbiology. PMID 34738268 DOI: 10.1111/mmi.14832 |
0.722 |
|
| 2020 |
Dimond ZE, Hefty PS. Comprehensive genome analysis and comparisons of the swine pathogen, Chlamydia suis reveals unique ORFs and candidate host-specificity factors. Pathogens and Disease. PMID 32639528 DOI: 10.1093/femspd/ftaa035 |
0.711 |
|
| 2019 |
Soules KR, Dmitriev A, LaBrie SD, Dimond ZE, May BH, Johnson DK, Zhang Y, Battaile KP, Lovell S, Hefty PS. Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis supports role in TCA cycle regulation. Molecular Microbiology. PMID 31637787 DOI: 10.1111/Mmi.14401 |
0.733 |
|
| 2019 |
Suchland RJ, Carrell SJ, Wang Y, Hybiske K, Kim DB, Dimond ZE, Hefty PS, Rockey DD. Chromosomal recombination targets in interspecies lateral gene transfer. Journal of Bacteriology. PMID 31501285 DOI: 10.1128/Jb.00365-19 |
0.776 |
|
| 2019 |
Wang Y, LaBrie SD, Carrell SJ, Suchland RJ, Dimond ZE, Kwong F, Rockey DD, Hefty PS, Hybiske K. Development of transposon mutagenesis for . Journal of Bacteriology. PMID 31501283 DOI: 10.1128/Jb.00366-19 |
0.796 |
|
| 2019 |
LaBrie SD, Dimond ZE, Harrison KS, Baid S, Wickstrum J, Suchland RJ, Hefty PS. Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer. Mbio. 10. PMID 31387908 DOI: 10.1128/Mbio.01343-19 |
0.799 |
|
| 2018 |
Cossé MM, Barta ML, Fisher DJ, Oesterlin LK, Niragire B, Perrinet S, Millot GA, Hefty PS, Subtil A. The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces Infectivity and Growth. Frontiers in Cellular and Infection Microbiology. 8: 145. PMID 29868501 DOI: 10.3389/Fcimb.2018.00145 |
0.832 |
|
| 2016 |
Brothwell JA, Muramatsu MK, Toh E, Rockey DD, Putman TE, Barta ML, Hefty PS, Suchland RJ, Nelson DE. Interrogating genes that mediate Chlamydia trachomatis survival in cell culture using conditional mutants and recombination. Journal of Bacteriology. PMID 27246568 DOI: 10.1128/Jb.00161-16 |
0.797 |
|
| 2015 |
Tifrea DF, Barta ML, Pal S, Hefty PS, de la Maza LM. Computational modeling of TC0583 as a putative component of the C. muridarum V-type ATP Synthase Complex and assessment of its protective capabilities as a vaccine antigen. Microbes and Infection / Institut Pasteur. PMID 26706820 DOI: 10.1016/J.Micinf.2015.12.002 |
0.787 |
|
| 2015 |
Barta ML, Battaile KP, Lovell S, Hefty PS. Hypothetical protein CT398 (CdsZ) interacts with σ(54) (RpoN)-holoenzyme and the type III secretion export apparatus in Chlamydia trachomatis. Protein Science : a Publication of the Protein Society. 24: 1617-32. PMID 26173998 DOI: 10.1002/Pro.2746 |
0.837 |
|
| 2015 |
Kemege KE, Hickey JM, Barta ML, Wickstrum J, Balwalli N, Lovell S, Battaile KP, Hefty PS. Chlamydia trachomatis protein CT009 is a structural and functional homolog to the key morphogenesis component RodZ and interacts with division septal plane localized MreB. Molecular Microbiology. 95: 365-82. PMID 25382739 DOI: 10.1111/Mmi.12855 |
0.718 |
|
| 2014 |
Barta ML, Thomas K, Yuan H, Lovell S, Battaile KP, Schramm VL, Hefty PS. Structural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway. The Journal of Biological Chemistry. 289: 32214-29. PMID 25253688 DOI: 10.1074/Jbc.M114.594325 |
0.819 |
|
| 2014 |
Osaka I, Hefty PS. Lipopolysaccharide-binding alkylpolyamine DS-96 inhibits Chlamydia trachomatis infection by blocking attachment and entry. Antimicrobial Agents and Chemotherapy. 58: 3245-54. PMID 24663021 DOI: 10.1128/Aac.02391-14 |
0.775 |
|
| 2014 |
Barta ML, Hickey JM, Anbanandam A, Dyer K, Hammel M, Hefty PS. Atypical response regulator ChxR from Chlamydia trachomatis is structurally poised for DNA binding. Plos One. 9: e91760. PMID 24646934 DOI: 10.1371/Journal.Pone.0091760 |
0.785 |
|
| 2014 |
Barta ML, Lovell S, Sinclair AN, Battaile KP, Hefty PS. Chlamydia trachomatis CT771 (nudH) is an asymmetric Ap4A hydrolase. Biochemistry. 53: 214-24. PMID 24354275 DOI: 10.1021/Bi401473E |
0.816 |
|
| 2013 |
Barta ML, Hickey J, Kemege KE, Lovell S, Battaile KP, Hefty PS. Structure of CT584 from Chlamydia trachomatis refined to 3.05 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1196-201. PMID 24192348 DOI: 10.1107/S1744309113027371 |
0.789 |
|
| 2013 |
Wickstrum J, Sammons LR, Restivo KN, Hefty PS. Conditional gene expression in Chlamydia trachomatis using the tet system. Plos One. 8: e76743. PMID 24116144 DOI: 10.1371/Journal.Pone.0076743 |
0.76 |
|
| 2013 |
Koppolu V, Osaka I, Skredenske JM, Kettle B, Hefty PS, Li J, Egan SM. Small-molecule inhibitor of the Shigella flexneri master virulence regulator VirF. Infection and Immunity. 81: 4220-31. PMID 24002059 DOI: 10.1128/Iai.00919-13 |
0.794 |
|
| 2013 |
Osaka I, Hefty PS. Simple resazurin-based microplate assay for measuring Chlamydia infections. Antimicrobial Agents and Chemotherapy. 57: 2838-40. PMID 23507273 DOI: 10.1128/Aac.00056-13 |
0.758 |
|
| 2012 |
Osaka I, Hills JM, Kieweg SL, Shinogle HE, Moore DS, Hefty PS. An automated image-based method for rapid analysis of Chlamydia infection as a tool for screening antichlamydial agents. Antimicrobial Agents and Chemotherapy. 56: 4184-8. PMID 22615279 DOI: 10.1128/Aac.00427-12 |
0.756 |
|
| 2011 |
Kemege KE, Hickey JM, Lovell S, Battaile KP, Zhang Y, Hefty PS. Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes. Journal of Bacteriology. 193: 6517-28. PMID 21965559 DOI: 10.1128/Jb.05488-11 |
0.799 |
|
| 2011 |
Hickey JM, Lovell S, Battaile KP, Hu L, Middaugh CR, Hefty PS. The atypical response regulator protein ChxR has structural characteristics and dimer interface interactions that are unique within the OmpR/PhoB subfamily. The Journal of Biological Chemistry. 286: 32606-16. PMID 21775428 DOI: 10.1074/jbc.M111.220574 |
0.758 |
|
| 2011 |
Hickey JM, Weldon L, Hefty PS. The atypical OmpR/PhoB response regulator ChxR from Chlamydia trachomatis forms homodimers in vivo and binds a direct repeat of nucleotide sequences. Journal of Bacteriology. 193: 389-98. PMID 21057008 DOI: 10.1128/JB.00833-10 |
0.757 |
|
| 2009 |
Markham AP, Jaafar ZA, Kemege KE, Middaugh CR, Hefty PS. Biophysical characterization of Chlamydia trachomatis CT584 supports its potential role as a type III secretion needle tip protein. Biochemistry. 48: 10353-61. PMID 19769366 DOI: 10.1021/Bi901200Y |
0.805 |
|
| 2009 |
Hickey JM, Hefty PS, Lamb AL. Expression, purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of a Chlamydia trachomatis OmpR/PhoB-subfamily response regulator homolog, ChxR Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 791-794. PMID 19652341 DOI: 10.1107/S1744309109025184 |
0.755 |
|
| 2009 |
Abromaitis S, Hefty PS, Stephens RS. Chlamydia pneumoniae encodes a functional aromatic amino acid hydroxylase. Fems Immunology and Medical Microbiology. 55: 196-205. PMID 19141112 DOI: 10.1111/J.1574-695X.2008.00511.X |
0.781 |
|
| 2008 |
Alitalo A, Meri T, Lankinen H, Cheng Z, Jokiranta S, Seppälä I, Lahdenne P, Brooks C, Hefty PS, Akins DR, Meri S. Lysine-Dependent Binding of OspE to the C-terminus of Factor H Mediates Complement Resistance in Borrelia burgdorferi Scandinavian Journal of Immunology. 59: 624-625. DOI: 10.1111/J.0300-9475.2004.01423Aj.X |
0.769 |
|
| 2007 |
Hefty PS, Stephens RS. Chlamydial type III secretion system is encoded on ten operons preceded by sigma 70-like promoter elements. Journal of Bacteriology. 189: 198-206. PMID 17056752 DOI: 10.1128/Jb.01034-06 |
0.763 |
|
| 2006 |
Koo IC, Walthers D, Hefty PS, Kenney LJ, Stephens RS. ChxR is a transcriptional activator in Chlamydia. Proceedings of the National Academy of Sciences of the United States of America. 103: 750-5. PMID 16407127 DOI: 10.1073/Pnas.0509690103 |
0.774 |
|
| 2006 |
Hua L, Hefty PS, Lee YJ, Lee YM, Stephens RS, Price CW. Core of the partner switching signalling mechanism is conserved in the obligate intracellular pathogen Chlamydia trachomatis. Molecular Microbiology. 59: 623-36. PMID 16390455 DOI: 10.1111/J.1365-2958.2005.04962.X |
0.772 |
|
| 2004 |
Alitalo A, Meri T, Chen T, Lankinen H, Cheng ZZ, Jokiranta TS, Seppälä IJ, Lahdenne P, Hefty PS, Akins DR, Meri S. Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H. Journal of Immunology (Baltimore, Md. : 1950). 172: 6195-201. PMID 15128807 |
0.758 |
|
| 2003 |
Brooks CS, Hefty PS, Jolliff SE, Akins DR. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infection and Immunity. 71: 3371-83. PMID 12761121 DOI: 10.1128/Iai.71.6.3371-3383.2003 |
0.795 |
|
| 2002 |
Hefty PS, Brooks CS, Jett AM, White GL, Wikel SK, Kennedy RC, Akins DR. OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human lyme disease patients. Journal of Clinical Microbiology. 40: 4256-65. PMID 12409407 DOI: 10.1128/Jcm.40.11.4256-4265.2002 |
0.766 |
|
| 2002 |
Alitalo A, Meri T, Lankinen H, Seppälä I, Lahdenne P, Hefty PS, Akins D, Meri S. Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. Journal of Immunology (Baltimore, Md. : 1950). 169: 3847-53. PMID 12244181 DOI: 10.4049/Jimmunol.169.7.3847 |
0.771 |
|
| 2002 |
Hefty PS, Jolliff SE, Caimano MJ, Wikel SK, Akins DR. Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi. Infection and Immunity. 70: 3468-78. PMID 12065486 DOI: 10.1128/IAI.70.7.3468-3478.2002 |
0.764 |
|
| 2001 |
Hefty PS, Jolliff SE, Caimano MJ, Wikel SK, Radolf JD, Akins DR. Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signals. Infection and Immunity. 69: 3618-27. PMID 11349022 DOI: 10.1128/IAI.69.6.3618-3627.2001 |
0.808 |
|
| 1999 |
Watts AM, Stanley JR, Shearer MH, Hefty PS, Kennedy RC. Fetal immunization of baboons induces a fetal-specific antibody response. Nature Medicine. 5: 427-30. PMID 10202933 DOI: 10.1038/7426 |
0.651 |
|
| 1999 |
Hefty PS, Kennedy RC. Immunoglobulin variable regions as idiotype vaccines. Infectious Disease Clinics of North America. 13: 27-37, vi. PMID 10198790 DOI: 10.1016/S0891-5520(05)70041-6 |
0.65 |
|
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